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product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Oxazepam
catalog :
O5254
citations: 67
Reference
Klaminder J, Brodin T, Sundelin A, Anderson N, Fahlman J, Jonsson M, et al. Long-Term Persistence of an Anxiolytic Drug (Oxazepam) in a Large Freshwater Lake. Environ Sci Technol. 2015;49:10406-12 pubmed publisher
Battal D, Barnes A, Castaneto M, Martin T, Klette K, Huestis M. Urine Mescaline Screening With a Biochip Array Immunoassay and Quantification by Gas Chromatography-Mass Spectrometry. Ther Drug Monit. 2015;37:805-11 pubmed publisher
Xiong L, Wang R, Liang C, Teng X, Jiang F, Zeng L, et al. Determination of co-administrated opioids and benzodiazepines in urine using column-switching solid-phase extraction and liquid chromatography-tandem mass spectrometry. J Chromatogr A. 2015;1395:99-108 pubmed publisher
Thompson T, Grabowski Boase L, Tarantino L. Prototypical anxiolytics do not reduce anxiety-like behavior in the open field in C57BL/6J mice. Pharmacol Biochem Behav. 2015;133:7-17 pubmed publisher
Mimura H, Kobayashi K, Xu L, Hashimoto M, Ejiri Y, Hosoda M, et al. Effects of cytokines on CYP3A4 expression and reversal of the effects by anti-cytokine agents in the three-dimensionally cultured human hepatoma cell line FLC-4. Drug Metab Pharmacokinet. 2015;30:105-10 pubmed publisher
Stephanson N, Sandqvist S, Lambert M, Beck O. Method validation and application of a liquid chromatography-tandem mass spectrometry method for drugs of abuse testing in exhaled breath. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;985:189-96 pubmed publisher
Shayesteh T, Radmehr M, Khajavi F, Mahjub R. Application of chemometrics in determination of the acid dissociation constants (pKa) of several benzodiazepine derivatives as poorly soluble drugs in the presence of ionic surfactants. Eur J Pharm Sci. 2015;69:44-50 pubmed publisher
Sempio C, Morini L, Vignali C, Groppi A. Simple and sensitive screening and quantitative determination of 88 psychoactive drugs and their metabolites in blood through LC-MS/MS: application on postmortem samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;970:1-7 pubmed publisher
Bertol E, Mari F, Boscolo Berto R, Mannaioni G, Vaiano F, Favretto D. A mixed MDPV and benzodiazepine intoxication in a chronic drug abuser: determination of MDPV metabolites by LC-HRMS and discussion of the case. Forensic Sci Int. 2014;243:149-55 pubmed publisher
De Vrieze M, Verzele D, Szucs R, Sandra P, Lynen F. Evaluation of sphingomyelin, cholester, and phosphatidylcholine-based immobilized artificial membrane liquid chromatography to predict drug penetration across the blood-brain barrier. Anal Bioanal Chem. 2014;406:6179-88 pubmed publisher
Beck O, Carlsson S, Tusic M, Olsson R, Franzen L, Hultén P. Laboratory and clinical evaluation of on-site urine drug testing. Scand J Clin Lab Invest. 2014;74:681-6 pubmed publisher
Carlier J, Romeuf L, Guitton J, Priez Barallon C, Bevalot F, Fanton L, et al. A validated method for quantifying atractyloside and carboxyatractyloside in blood by HPLC-HRMS/MS, a non-fatal case of intoxication with Atractylis gummifera L. J Anal Toxicol. 2014;38:619-27 pubmed publisher
Maublanc J, Dulaurent S, Morichon J, Lachâtre G, Gaulier J. Identification and quantification of 35 psychotropic drugs and metabolites in hair by LC-MS/MS: application in forensic toxicology. Int J Legal Med. 2015;129:259-68 pubmed publisher
Fisher J, Taori G, Braitberg G, Graudins A. Methylene blue used in the treatment of refractory shock resulting from drug poisoning. Clin Toxicol (Phila). 2014;52:63-5 pubmed publisher
Brodin T, Fick J, Jonsson M, Klaminder J. Dilute concentrations of a psychiatric drug alter behavior of fish from natural populations. Science. 2013;339:814-5 pubmed publisher
Ganji M, Nashtahosseini M, Yeganegi S, Rezvani M. First-principles vdW-DF investigation on the interaction between the oxazepam molecule and C₆₀ fullerene. J Mol Model. 2013;19:1929-36 pubmed publisher
Sarris J, Laporte E, Scholey A, King R, Pipingas A, Schweitzer I, et al. Does a medicinal dose of kava impair driving? A randomized, placebo-controlled, double-blind study. Traffic Inj Prev. 2013;14:13-7 pubmed publisher
Flodin P, Gospic K, Petrovic P, Fransson P. Effects of L-dopa and oxazepam on resting-state functional magnetic resonance imaging connectivity: a randomized, cross-sectional placebo study. Brain Connect. 2012;2:246-53 pubmed publisher
Marin S, Roberts M, Wood M, McMillin G. Sensitive UPLC-MS-MS assay for 21 benzodiazepine drugs and metabolites, zolpidem and zopiclone in serum or plasma. J Anal Toxicol. 2012;36:472-6 pubmed publisher
Bailes J, Mayoss S, Teale P, Soloviev M. Gold nanoparticle antibody conjugates for use in competitive lateral flow assays. Methods Mol Biol. 2012;906:45-55 pubmed publisher
Goeders N, Cohen A, Fox B, Azar M, George O, Koob G. Effects of the combination of metyrapone and oxazepam on intravenous nicotine self-administration in rats. Psychopharmacology (Berl). 2012;223:17-25 pubmed publisher
Chang Q, Ma H, Wang F, Ou H, Zou M. [Determination of 10 sedative-hypnotics in human plasma using pulse splitless injection technique and gas chromatography-mass spectrometry]. Se Pu. 2011;29:1082-6 pubmed
Sarris J, Scholey A, Schweitzer I, Bousman C, Laporte E, Ng C, et al. The acute effects of kava and oxazepam on anxiety, mood, neurocognition; and genetic correlates: a randomized, placebo-controlled, double-blind study. Hum Psychopharmacol. 2012;27:262-9 pubmed publisher
Naggar A, ElKaoutit M, Naranjo Rodriguez I, El Sayed A, de Cisneros J. Use of a Sonogel-Carbon electrode modified with bentonite for the determination of diazepam and chlordiazepoxide hydrochloride in tablets and their metabolite oxazepam in urine. Talanta. 2012;89:448-54 pubmed publisher
Kablinger A, Lindner M, Casso S, Hefti F, Demuth G, Fox B, et al. Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study. J Psychopharmacol. 2012;26:973-81 pubmed publisher
Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W. Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS Comput Biol. 2011;7:e1002310 pubmed publisher
Kosjek T, Perko S, Zupanc M, Zanoški Hren M, Landeka Dragicević T, Zigon D, et al. Environmental occurrence, fate and transformation of benzodiazepines in water treatment. Water Res. 2012;46:355-68 pubmed publisher
Kukanich B, Nauss J. Pharmacokinetics of the cytochrome P-450 substrates phenytoin, theophylline, and diazepam in healthy Greyhound dogs. J Vet Pharmacol Ther. 2012;35:275-81 pubmed publisher
Chin P, Jensen B, Larsen H, Begg E. Adult age and ex vivo protein binding of lorazepam, oxazepam and temazepam in healthy subjects. Br J Clin Pharmacol. 2011;72:985-9 pubmed publisher
Franck M, Foulon V, Van Vaerenbergh L. ABOP, the automatic patient information leaflet optimizer: evaluation of a tool in development. Patient Educ Couns. 2011;83:411-6 pubmed publisher
Gospic K, Mohlin E, Fransson P, Petrovic P, Johannesson M, Ingvar M. Limbic justice--amygdala involvement in immediate rejection in the Ultimatum Game. PLoS Biol. 2011;9:e1001054 pubmed publisher
Larsen H, Chin P, Begg E, Jensen B. Quantification of total and unbound concentrations of lorazepam, oxazepam and temazepam in human plasma by ultrafiltration and LC-MS/MS. Bioanalysis. 2011;3:843-52 pubmed publisher
Gozalbes R, Jacewicz M, Annand R, Tsaioun K, Pineda Lucena A. QSAR-based permeability model for drug-like compounds. Bioorg Med Chem. 2011;19:2615-24 pubmed publisher
Uzun S, Kozumplik O. Reinforcement of irritability during therapy with benzodiazepines. Psychiatr Danub. 2011;23:129-30 pubmed
Sabljić V, Rakun R, Ružić K, Grahovac T. Duloxetine-related panic attacks. Psychiatr Danub. 2011;23:114-6 pubmed
Tabrizi A, Harasi M. Applying cloud point extraction technique for the extraction of oxazepam from human urine as a colour or fluorescent derivative prior to spectroscopic analysis methods. Drug Test Anal. 2012;4:145-50 pubmed publisher
Hellrup J, Mahlin D. Pharmaceutical micro-particles give amorphous sucrose higher physical stability. Int J Pharm. 2011;409:96-103 pubmed publisher
Lusthof K, Oosting R, Maes A, Verschraagen M, Dijkhuizen A, Sprong A. A case of extreme agitation and death after the use of mephedrone in The Netherlands. Forensic Sci Int. 2011;206:e93-5 pubmed publisher
Musulin S, Mariani C, Papich M. Diazepam pharmacokinetics after nasal drop and atomized nasal administration in dogs. J Vet Pharmacol Ther. 2011;34:17-24 pubmed publisher
Olofsson J, Gospic K, Petrovic P, Ingvar M, Wiens S. Effects of oxazepam on affective perception, recognition, and event-related potentials. Psychopharmacology (Berl). 2011;215:301-9 pubmed publisher
Lahousse S, Hoenerhoff M, Collins J, Ton T, Masinde T, Olson D, et al. Gene expression and mutation assessment provide clues of genetic and epigenetic mechanisms in liver tumors of oxazepam-exposed mice. Vet Pathol. 2011;48:875-84 pubmed publisher
Prado Prado F, Garcia Mera X, González Díaz H. Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorg Med Chem. 2010;18:2225-2231 pubmed publisher
Varma M, Obach R, Rotter C, Miller H, Chang G, Steyn S, et al. Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. J Med Chem. 2010;53:1098-108 pubmed publisher
Guerra A, Campillo N, Paez J. Neural computational prediction of oral drug absorption based on CODES 2D descriptors. Eur J Med Chem. 2010;45:930-40 pubmed publisher
Fourches D, Barnes J, Day N, Bradley P, Reed J, Tropsha A. Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chem Res Toxicol. 2010;23:171-83 pubmed publisher
Sui X, Sun J, Li H, Wang Y, Liu J, Liu X, et al. Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. Eur J Med Chem. 2009;44:4455-60 pubmed publisher
Varma M, Feng B, Obach R, Troutman M, Chupka J, Miller H, et al. Physicochemical determinants of human renal clearance. J Med Chem. 2009;52:4844-52 pubmed publisher
Li H, Sun J, Sui X, Liu J, Yan Z, Liu X, et al. First-principle, structure-based prediction of hepatic metabolic clearance values in human. Eur J Med Chem. 2009;44:1600-6 pubmed publisher
Pedersen J, Matsson P, Bergström C, Norinder U, Hoogstraate J, Artursson P. Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). J Med Chem. 2008;51:3275-87 pubmed publisher
Obach R, Lombardo F, Waters N. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug Metab Dispos. 2008;36:1385-405 pubmed publisher
Wassvik C, Holmén A, Draheim R, Artursson P, Bergström C. Molecular characteristics for solid-state limited solubility. J Med Chem. 2008;51:3035-9 pubmed publisher
Lazaro E, Lowe P, Briand X, Faller B. New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin. J Med Chem. 2008;51:2009-17 pubmed publisher
Du Cuny L, Huwyler J, Wiese M, Kansy M. Computational aqueous solubility prediction for drug-like compounds in congeneric series. Eur J Med Chem. 2008;43:501-12 pubmed
Ottaviani G, Martel S, Carrupt P. In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities. J Med Chem. 2007;50:742-8 pubmed
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Kiang T, Ensom M, Chang T. UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacol Ther. 2005;106:97-132 pubmed
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Laviola G. On mouse pups and their lactating dams: behavioral consequences of early exposure to oxazepam and interacting factors. Pharmacol Biochem Behav. 1996;55:459-74 pubmed
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product information
Catalog Number :
O5254
Product Name :
Oxazepam
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA