This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
N-Oleoylethanolamine
catalog :
O0383
citations: 115
Reference
Liu Y, Liu Q, Krivoruchko A, Khoomrung S, Nielsen J. Engineering yeast phospholipid metabolism for de novo oleoylethanolamide production. Nat Chem Biol. 2020;16:197-205 pubmed publisher
Cristino L, Bisogno T, Di Marzo V. Cannabinoids and the expanded endocannabinoid system in neurological disorders. Nat Rev Neurol. 2020;16:9-29 pubmed publisher
Cravens E, Kirkwood J, Wolfe L, Packer R, Whalen L, Wojda S, et al. The effects of neurectomy and hibernation on bone properties and the endocannabinoid system in marmots (Marmota flaviventris). Comp Biochem Physiol A Mol Integr Physiol. 2020;241:110621 pubmed publisher
Carta G, Murru E, Manca C, Serra A, Mele M, Banni S. Natural CLA-Enriched Lamb Meat Fat Modifies Tissue Fatty Acid Profile and Increases n-3 HUFA Score in Obese Zucker Rats. Biomolecules. 2019;9: pubmed publisher
Giacovazzo G, Bisogno T, Piscitelli F, Verde R, Oddi S, Maccarrone M, et al. Different Routes to Inhibit Fatty Acid Amide Hydrolase: Do All Roads Lead to the Same Place?. Int J Mol Sci. 2019;20: pubmed publisher
Martin G, Seeger D, McIntosh A, Milligan S, Chung S, Landrock D, et al. Sterol Carrier Protein-2/Sterol Carrier Protein-x/Fatty Acid Binding Protein-1 Ablation Impacts Response of Brain Endocannabinoid to High-Fat Diet. Lipids. 2019;54:583-601 pubmed publisher
Dempsey S, Gesseck A, Ahmad A, Daneva Z, Ritter J, Poklis J. Formation of HETE-EAs and dihydroxy derivatives in mouse kidney tissue and analysis by high-performance liquid chromatography tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2019;1126-1127:121748 pubmed publisher
De Luca L, Ferracane R, Vitaglione P. Food database of N-acyl-phosphatidylethanolamines, N-acylethanolamines and endocannabinoids and daily intake from a Western, a Mediterranean and a vegetarian diet. Food Chem. 2019;300:125218 pubmed publisher
Son B, Lee K, Kim T, Shin M, Choi S, Cho G. Purification and Nitrogen Doping of Nanothin Exfoliated Graphite Through RF Thermal Plasma Treatment. Nanomaterials (Basel). 2019;9: pubmed publisher
TuTunchi H, Ostadrahimi A, Saghafi Asl M, Maleki V. The effects of oleoylethanolamide, an endogenous PPAR-α agonist, on risk factors for NAFLD: A systematic review. Obes Rev. 2019;20:1057-1069 pubmed publisher
Zeng K, Li Y, Yang W, Ge Y, Xu L, Ren T, et al. Moringa oleifera seed extract protects against brain damage in both the acute and delayed stages of ischemic stroke. Exp Gerontol. 2019;122:99-108 pubmed publisher
Bystrowska B, Frankowska M, Smaga I, Niedzielska Andres E, Pomierny Chamioło L, Filip M. Cocaine-Induced Reinstatement of Cocaine Seeking Provokes Changes in the Endocannabinoid and N-Acylethanolamine Levels in Rat Brain Structures. Molecules. 2019;24: pubmed publisher
Yao E, Zhang G, Huang J, Yang X, Peng L, Huang X, et al. Immunomodulatory effect of oleoylethanolamide in dendritic cells via TRPV1/AMPK activation. J Cell Physiol. 2019;: pubmed publisher
Kita M, Ano Y, Inoue A, Aoki J. Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells. Sci Rep. 2019;9:3135 pubmed publisher
Rahman A, Pallichankandy S, Thayyullathil F, Galadari S. Critical role of H2O2 in mediating sanguinarine-induced apoptosis in prostate cancer cells via facilitating ceramide generation, ERK1/2 phosphorylation, and Par-4 cleavage. Free Radic Biol Med. 2019;134:527-544 pubmed publisher
Yang X, Xu L, Zhou J, Ge Y, Wu S, Huang J, et al. Integration of phospholipid-complex nanocarrier assembly with endogenous N-oleoylethanolamine for efficient stroke therapy. J Nanobiotechnology. 2019;17:8 pubmed publisher
Salaga M, Binienda A, Piscitelli F, Mokrowiecka A, Cygankiewicz A, Verde R, et al. Systemic administration of serotonin exacerbates abdominal pain and colitis via interaction with the endocannabinoid system. Biochem Pharmacol. 2019;161:37-51 pubmed publisher
Rivera P, Silva Peña D, Blanco E, Vargas A, Arrabal S, Serrano A, et al. Oleoylethanolamide restores alcohol-induced inhibition of neuronal proliferation and microglial activity in striatum. Neuropharmacology. 2019;146:184-197 pubmed publisher
Misto A, Provensi G, Vozella V, Passani M, Piomelli D. Mast Cell-Derived Histamine Regulates Liver Ketogenesis via Oleoylethanolamide Signaling. Cell Metab. 2019;29:91-102.e5 pubmed publisher
de Andrade L, Coelho F, Hassan S, Morris L, De Oliveira Camargo F. Sediment pollution in an urban water supply lake in southern Brazil. Environ Monit Assess. 2018;191:12 pubmed publisher
Chicca A, Schafroth M, Reynoso Moreno I, Erni R, Petrucci V, Carreira E, et al. Uncovering the psychoactivity of a cannabinoid from liverworts associated with a legal high. Sci Adv. 2018;4:eaat2166 pubmed publisher
Di Paola M, Bonechi E, Provensi G, Costa A, Clarke G, Ballerini C, et al. Oleoylethanolamide treatment affects gut microbiota composition and the expression of intestinal cytokines in Peyer's patches of mice. Sci Rep. 2018;8:14881 pubmed publisher
Perez P, DiPatrizio N. Impact of maternal western diet-induced obesity on offspring mortality and peripheral endocannabinoid system in mice. PLoS ONE. 2018;13:e0205021 pubmed publisher
Zhang C, Wang X, Anaya Y, Parodi L, Cheng L, Anderson M, et al. Distinct molecular pathways in ovarian endometrioid adenocarcinoma with concurrent endometriosis. Int J Cancer. 2018;143:2505-2515 pubmed publisher
Nieto A, Fernandez Vega V, Spicer T, Sturchler E, Adhikari P, Kennedy N, et al. Identification of Novel, Structurally Diverse, Small Molecule Modulators of GPR119. Assay Drug Dev Technol. 2018;16:278-288 pubmed publisher
Hegyi Z, Oláh T, Koszeghy A, Piscitelli F, Holló K, Pál B, et al. CB1 receptor activation induces intracellular Ca2+ mobilization and 2-arachidonoylglycerol release in rodent spinal cord astrocytes. Sci Rep. 2018;8:10562 pubmed publisher
Murru E, Carta G, Cordeddu L, Melis M, Desogus E, Ansar H, et al. Dietary Conjugated Linoleic Acid-Enriched Cheeses Influence the Levels of Circulating n-3 Highly Unsaturated Fatty Acids in Humans. Int J Mol Sci. 2018;19: pubmed publisher
Mulawa E, Kirkwood J, Wolfe L, Wojda S, Prenni J, Florant G, et al. Seasonal Changes in Endocannabinoid Concentrations between Active and Hibernating Marmots (Marmota flaviventris). J Biol Rhythms. 2018;33:388-401 pubmed publisher
Sihag J, Jones P. Dietary fatty acid composition impacts plasma fatty acid ethanolamide levels and body composition in golden Syrian hamsters. Food Funct. 2018;9:3351-3362 pubmed publisher
Yang Y, Zhong Q, Zhang H, Mo C, Yao J, Huang T, et al. Lipidomics study of the protective effects of isosteviol sodium on stroke rats using ultra high-performance supercritical fluid chromatography coupling with ion-trap and time-of-flight tandem mass spectrometry. J Pharm Biomed Anal. 2018;157:145-155 pubmed publisher
Martin G, Seeger D, McIntosh A, Chung S, Milligan S, Landrock D, et al. Scp-2/Scp-x ablation in Fabp1 null mice differentially impacts hepatic endocannabinoid level depending on dietary fat. Arch Biochem Biophys. 2018;650:93-102 pubmed publisher
Luque Córdoba D, Calderón Santiago M, Luque de Castro M, Priego Capote F. Study of sample preparation for determination of endocannabinoids and analogous compounds in human serum by LC-MS/MS in MRM mode. Talanta. 2018;185:602-610 pubmed publisher
Hinkovska Galcheva V, Kelly R, Manthei K, Bouley R, Yuan W, Schwendeman A, et al. Determinants of pH profile and acyl chain selectivity in lysosomal phospholipase A2. J Lipid Res. 2018;59:1205-1218 pubmed publisher
Price C, Argueta D, Medici V, Bremer A, Lee V, Nunez M, et al. Plasma fatty acid ethanolamides are associated with postprandial triglycerides, ApoCIII, and ApoE in humans consuming a high-fructose corn syrup-sweetened beverage. Am J Physiol Endocrinol Metab. 2018;315:E141-E149 pubmed publisher
Tough I, Forbes S, Herzog H, Jones R, Schwartz T, Cox H. Bidirectional GPR119 Agonism Requires Peptide YY and Glucose for Activity in Mouse and Human Colon Mucosa. Endocrinology. 2018;159:1704-1717 pubmed publisher
McIntosh A, Martin G, Huang H, Landrock D, Kier A, Schroeder F. Δ9-Tetrahydrocannabinol induces endocannabinoid accumulation in mouse hepatocytes: antagonism by Fabp1 gene ablation. J Lipid Res. 2018;59:646-657 pubmed publisher
Poddighe L, Carta G, Serra M, Melis T, Boi M, Lisai S, et al. Acute administration of beta-caryophyllene prevents endocannabinoid system activation during transient common carotid artery occlusion and reperfusion. Lipids Health Dis. 2018;17:23 pubmed publisher
Tomas Roig J, Piscitelli F, Gil V, Quintana E, Ramió Torrentà L, del Río J, et al. Effects of repeated long-term psychosocial stress and acute cannabinoid exposure on mouse corticostriatal circuitries: Implications for neuropsychiatric disorders. CNS Neurosci Ther. 2018;24:528-538 pubmed publisher
Drzazga A, Sowińska A, Krzemińska A, Okruszek A, Paneth P, Koziołkiewicz M, et al. 2-OMe-lysophosphatidylcholine analogues are GPR119 ligands and activate insulin secretion from βTC-3 pancreatic cells: Evaluation of structure-dependent biological activity. Biochim Biophys Acta Mol Cell Biol Lipids. 2018;1863:91-103 pubmed publisher
Cheng K, Sloan A, Waitt B, Vendramelli R, Godal D, Simon S, et al. Altered rPrP substrate structures and their influence on real-time quaking induced conversion reactions. Protein Expr Purif. 2018;143:20-27 pubmed publisher
Watabiki T, Tsuji N, Kiso T, Ozawa T, Narazaki F, Kakimoto S. In vitro and in vivo pharmacological characterization of ASP8477: A novel highly selective fatty acid amide hydrolase inhibitor. Eur J Pharmacol. 2017;815:42-48 pubmed publisher
Forner Piquer I, Maradonna F, Gioacchini G, Santangeli S, Allarà M, Piscitelli F, et al. Dose-Specific Effects of Di-Isononyl Phthalate on the Endocannabinoid System and on Liver of Female Zebrafish. Endocrinology. 2017;158:3462-3476 pubmed publisher
Zhou J, Ren T, Li Y, Cheng A, Xie W, Xu L, et al. Oleoylethanolamide inhibits α-melanocyte stimulating hormone-stimulated melanogenesis via ERK, Akt and CREB signaling pathways in B16 melanoma cells. Oncotarget. 2017;8:56868-56879 pubmed publisher
Karlsson J, Gouveia Figueira S, Alhouayek M, Fowler C. Effects of tumour necrosis factor ? upon the metabolism of the endocannabinoid anandamide in prostate cancer cells. PLoS ONE. 2017;12:e0185011 pubmed publisher
Yang Y, Zhong Q, Mo C, Zhang H, Zhou T, Tan W. Determination of endogenous inflammation-related lipid mediators in ischemic stroke rats using background subtracting calibration curves by liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2017;409:6537-6547 pubmed publisher
Wang Z, Bian L, Mo C, Kukula M, Schug K, Brotto M. Targeted quantification of lipid mediators in skeletal muscles using restricted access media-based trap-and-elute liquid chromatography-mass spectrometry. Anal Chim Acta. 2017;984:151-161 pubmed publisher
Kwok C, Devonshire I, Imraish A, Greenspon C, Lockwood S, Fielden C, et al. Age-dependent plasticity in endocannabinoid modulation of pain processing through postnatal development. Pain. 2017;158:2222-2232 pubmed publisher
Ding J, Luo X, Yao Y, Xiao H, Guo M. Investigation of changes in endocannabinoids and N-acylethanolamides in biofluids, and their correlations with female infertility. J Chromatogr A. 2017;1509:16-25 pubmed publisher
Miller S, Hu S, Leishman E, Morgan D, Wager Miller J, Mackie K, et al. A GPR119 Signaling System in the Murine Eye Regulates Intraocular Pressure in a Sex-Dependent Manner. Invest Ophthalmol Vis Sci. 2017;58:2930-2938 pubmed publisher
Drzazga A, Sowińska A, Krzemińska A, Rytczak P, Koziolkiewicz M, Gendaszewska Darmach E. Lysophosphatidylcholine elicits intracellular calcium signaling in a GPR55-dependent manner. Biochem Biophys Res Commun. 2017;489:242-247 pubmed publisher
Provensi G, Fabbri R, Munari L, Costa A, Baldi E, Bucherelli C, et al. Histaminergic Neurotransmission as a Gateway for the Cognitive Effect of Oleoylethanolamide in Contextual Fear Conditioning. Int J Neuropsychopharmacol. 2017;20:392-399 pubmed publisher
Gamelin F, Aucouturier J, Iannotti F, Piscitelli F, Mazzarella E, Aveta T, et al. Exercise training and high-fat diet elicit endocannabinoid system modifications in the rat hypothalamus and hippocampus. J Physiol Biochem. 2016;73:335-347 pubmed publisher
Dotsey E, Ushach I, Pone E, Nakajima R, Jasinskas A, Argueta D, et al. Transient Cannabinoid Receptor 2 Blockade during Immunization Heightens Intensity and Breadth of Antigen-specific Antibody Responses in Young and Aged mice. Sci Rep. 2017;7:42584 pubmed publisher
Cremon C, Stanghellini V, Barbaro M, Cogliandro R, Bellacosa L, Santos J, et al. Randomised clinical trial: the analgesic properties of dietary supplementation with palmitoylethanolamide and polydatin in irritable bowel syndrome. Aliment Pharmacol Ther. 2017;45:909-922 pubmed publisher
Quartu M, Poddighe L, Melis T, Serra M, Boi M, Lisai S, et al. Involvement of the endocannabinoid system in the physiological response to transient common carotid artery occlusion and reperfusion. Lipids Health Dis. 2017;16:14 pubmed publisher
Kantae V, Ogino S, Noga M, Harms A, van Dongen R, Onderwater G, et al. Quantitative profiling of endocannabinoids and related N-acylethanolamines in human CSF using nano LC-MS/MS. J Lipid Res. 2017;58:615-624 pubmed publisher
Lerner R, Post J, Loch S, Lutz B, Bindila L. Targeting brain and peripheral plasticity of the lipidome in acute kainic acid-induced epileptic seizures in mice via quantitative mass spectrometry. Biochim Biophys Acta Mol Cell Biol Lipids. 2017;1862:255-267 pubmed publisher
Prospero Garcia O, Amancio Belmont O, Becerril Meléndez A, Ruiz Contreras A, Méndez Díaz M. Endocannabinoids and sleep. Neurosci Biobehav Rev. 2016;71:671-679 pubmed publisher
Okine B, Madasu M, McGowan F, Prendergast C, Gaspar J, Harhen B, et al. N-palmitoylethanolamide in the anterior cingulate cortex attenuates inflammatory pain behaviour indirectly via a CB1 receptor-mediated mechanism. Pain. 2016;157:2687-2696 pubmed
Martella A, Sepe R, Silvestri C, Zang J, Fasano G, Carnevali O, et al. Important role of endocannabinoid signaling in the development of functional vision and locomotion in zebrafish. FASEB J. 2016;30:4275-4288 pubmed
Karwad M, Macpherson T, Wang B, Theophilidou E, Sarmad S, Barrett D, et al. Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPAR?. FASEB J. 2017;31:469-481 pubmed publisher
Tomas Roig J, Benito E, Agis Balboa R, Piscitelli F, Hoyer Fender S, Di Marzo V, et al. Chronic exposure to cannabinoids during adolescence causes long-lasting behavioral deficits in adult mice. Addict Biol. 2017;22:1778-1789 pubmed publisher
Hellström F, Gouveia Figueira S, Nording M, Björklund M, Fowler C. Association between plasma concentrations of linoleic acid-derived oxylipins and the perceived pain scores in an exploratory study in women with chronic neck pain. BMC Musculoskelet Disord. 2016;17:103 pubmed publisher
Pu S, Eck P, Jenkins D, Connelly P, Lamarche B, Kris Etherton P, et al. Interactions between dietary oil treatments and genetic variants modulate fatty acid ethanolamides in plasma and body weight composition. Br J Nutr. 2016;115:1012-23 pubmed publisher
Krott L, Piscitelli F, Heine M, Borrino S, Scheja L, Silvestri C, et al. Endocannabinoid regulation in white and brown adipose tissue following thermogenic activation. J Lipid Res. 2016;57:464-73 pubmed publisher
Roh J, Park J, Kim E, Jang H. Targeting acid ceramidase sensitises head and neck cancer to cisplatin. Eur J Cancer. 2016;52:163-72 pubmed publisher
Lowin T, Apitz M, Anders S, Straub R. Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner. Arthritis Res Ther. 2015;17:321 pubmed publisher
Staiano R, Loffredo S, Borriello F, Iannotti F, Piscitelli F, Orlando P, et al. Human lung-resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors. J Leukoc Biol. 2016;99:531-40 pubmed publisher
Kaczocha M, Glaser S, Maher T, Clavin B, Hamilton J, O Rourke J, et al. Fatty acid binding protein deletion suppresses inflammatory pain through endocannabinoid/N-acylethanolamine-dependent mechanisms. Mol Pain. 2015;11:52 pubmed publisher
Ma L, Guo X, Chen W. Inhibitory effects of oleoylethanolamide (OEA) on H₂O₂-induced human umbilical vein endothelial cell (HUVEC) injury and apolipoprotein E knockout (ApoE-/-) atherosclerotic mice. Int J Clin Exp Pathol. 2015;8:6301-11 pubmed
Guida F, Luongo L, Marmo F, Romano R, Iannotta M, Napolitano F, et al. Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice. Mol Brain. 2015;8:47 pubmed publisher
Igarashi M, DiPatrizio N, Narayanaswami V, Piomelli D. Feeding-induced oleoylethanolamide mobilization is disrupted in the gut of diet-induced obese rodents. Biochim Biophys Acta. 2015;1851:1218-26 pubmed publisher
Sospedra I, Moral R, Escrich R, Solanas M, Vela E, Escrich E. Effect of High Fat Diets on Body Mass, Oleylethanolamide Plasma Levels and Oxytocin Expression in Growing Rats. J Food Sci. 2015;80:H1425-31 pubmed publisher
Cheng Y, Ho M, Huang W, Chou Y, King K. Modulation of Glucagon-like Peptide-1 (GLP-1) Potency by Endocannabinoid-like Lipids Represents a Novel Mode of Regulating GLP-1 Receptor Signaling. J Biol Chem. 2015;290:14302-13 pubmed publisher
Bull C, Syed W, Minter S, Bowers M. Differential response of glial fibrillary acidic protein-positive astrocytes in the rat prefrontal cortex following ethanol self-administration. Alcohol Clin Exp Res. 2015;39:650-8 pubmed publisher
Khaliullina H, Bilgin M, Sampaio J, Shevchenko A, Eaton S. Endocannabinoids are conserved inhibitors of the Hedgehog pathway. Proc Natl Acad Sci U S A. 2015;112:3415-20 pubmed publisher
Petrosino S, Schiano Moriello A, Cerrato S, Fusco M, Puigdemont A, De Petrocellis L, et al. The anti-inflammatory mediator palmitoylethanolamide enhances the levels of 2-arachidonoyl-glycerol and potentiates its actions at TRPV1 cation channels. Br J Pharmacol. 2016;173:1154-62 pubmed publisher
Karlsson C, Hjorth S, Karpefors M, Hansson G, Carlsson B. Baseline anandamide levels and body weight impact the weight loss effect of CB1 receptor antagonism in male rats. Endocrinology. 2015;156:1237-41 pubmed publisher
Ivanov I, Borchert P, Hinz B. A simple method for simultaneous determination of N-arachidonoylethanolamine, N-oleoylethanolamine, N-palmitoylethanolamine and 2-arachidonoylglycerol in human cells. Anal Bioanal Chem. 2015;407:1781-7 pubmed publisher
Martinez A, Morgese M, Pisanu A, Macheda T, Paquette M, Seillier A, et al. Activation of PPAR gamma receptors reduces levodopa-induced dyskinesias in 6-OHDA-lesioned rats. Neurobiol Dis. 2015;74:295-304 pubmed publisher
Engelstoft M, Norn C, Hauge M, Holliday N, Elster L, Lehmann J, et al. Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119. Br J Pharmacol. 2014;171:5774-89 pubmed publisher
Balakrishna S, Song W, Achanta S, Doran S, Liu B, Kaelberer M, et al. TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2014;307:L158-72 pubmed publisher
Tellez L, Medina S, Han W, Ferreira J, Licona Limón P, Ren X, et al. A gut lipid messenger links excess dietary fat to dopamine deficiency. Science. 2013;341:800-2 pubmed publisher
Syed S, Bui H, Beavers L, Farb T, Ficorilli J, Chesterfield A, et al. Regulation of GPR119 receptor activity with endocannabinoid-like lipids. Am J Physiol Endocrinol Metab. 2012;303:E1469-78 pubmed publisher
Voitychuk O, Asmolkova V, Gula N, Sotkis G, Galadari S, Howarth F, et al. Modulation of excitability, membrane currents and survival of cardiac myocytes by N-acylethanolamines. Biochim Biophys Acta. 2012;1821:1167-76 pubmed publisher
Ramirez de Molina A, de la Cueva A, Machado Pinilla R, Rodriguez Fanjul V, Gomez del Pulgar T, Cebrian A, et al. Acid ceramidase as a chemotherapeutic target to overcome resistance to the antitumoral effect of choline kinase ? inhibition. Curr Cancer Drug Targets. 2012;12:617-24 pubmed
Wheal A, Alexander S, Randall M. Hydrogen peroxide as a mediator of vasorelaxation evoked by N-oleoylethanolamine and anandamide in rat small mesenteric arteries. Eur J Pharmacol. 2012;674:384-90 pubmed publisher
Hamtiaux L, Hansoulle L, Dauguet N, Muccioli G, Gallez B, Lambert D. Increasing antiproliferative properties of endocannabinoids in N1E-115 neuroblastoma cells through inhibition of their metabolism. PLoS ONE. 2011;6:e26823 pubmed publisher
Heyman E, Gamelin F, Goekint M, Piscitelli F, Roelands B, Leclair E, et al. Intense exercise increases circulating endocannabinoid and BDNF levels in humans--possible implications for reward and depression. Psychoneuroendocrinology. 2012;37:844-51 pubmed publisher
Tsuboi K, Okamoto Y, Ikematsu N, Inoue M, Shimizu Y, Uyama T, et al. Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways. Biochim Biophys Acta. 2011;1811:565-77 pubmed publisher
Gouaze Andersson V, Flowers M, Karimi R, Fabrias G, Delgado A, Casas J, et al. Inhibition of acid ceramidase by a 2-substituted aminoethanol amide synergistically sensitizes prostate cancer cells to N-(4-hydroxyphenyl) retinamide. Prostate. 2011;71:1064-73 pubmed publisher
Sarmad S, Alexander S, Barrett D, Marsden C, Kendall D. Depolarizing and calcium-mobilizing stimuli fail to enhance synthesis and release of endocannabinoids from rat brain cerebral cortex slices. J Neurochem. 2011;117:665-77 pubmed publisher
Psychogios N, Hau D, Peng J, Guo A, Mandal R, Bouatra S, et al. The human serum metabolome. PLoS ONE. 2011;6:e16957 pubmed publisher
Voĭtychuk O, Asmolkova V, Hula N, Oz M, Shuba I. [Effects of N-stearoyl- and N-oleoylethanolamine on cardiac voltage-dependent sodium channels]. Fiziol Zh. 2010;56:13-22 pubmed
Sharma K, Singh R, Kandaswamy M, Mithra C, Giri S, Rajagopal S, et al. LC-MS/MS-ESI method for simultaneous quantitation of three endocannabinoids and its application to rat pharmacokinetic studies. Bioanalysis. 2011;3:181-96 pubmed publisher
Johnston T, Huot P, Fox S, Wakefield J, Sykes K, Bartolini W, et al. Fatty acid amide hydrolase (FAAH) inhibition reduces L-3,4-dihydroxyphenylalanine-induced hyperactivity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned non-human primate model of Parkinson's disease. J Pharmacol Exp Ther. 2011;336:423-30 pubmed publisher
Wheal A, Alexander S, Randall M. Vasorelaxation to N-oleoylethanolamine in rat isolated arteries: mechanisms of action and modulation via cyclooxygenase activity. Br J Pharmacol. 2010;160:701-11 pubmed publisher
Ying Ying Y, Lin H. Endocannabinoids and non-endocannabinoid fatty acid amides in cirrhosis. Liver Int. 2010;30:780-1 pubmed publisher
Kang M, Ahn K, Kim S, Jeon H, Ji J, Choi J, et al. Hypoxia-induced neuronal apoptosis is mediated by de novo synthesis of ceramide through activation of serine palmitoyltransferase. Cell Signal. 2010;22:610-8 pubmed publisher
Caraceni P, Viola A, Piscitelli F, Giannone F, Berzigotti A, Cescon M, et al. Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. Liver Int. 2010;30:816-25 pubmed publisher
Voĭtychuk O, Asmolkova V, Hula N, Sotkis H, Oz M, Shuba I. [Regulation of the excitability of neonatal cardiomyocytes by N-stearoyl- and N-oleoyl-ethanolamines]. Fiziol Zh. 2009;55:55-66 pubmed
Izzo A, Piscitelli F, Capasso R, Marini P, Cristino L, Petrosino S, et al. Basal and fasting/refeeding-regulated tissue levels of endogenous PPAR-alpha ligands in Zucker rats. Obesity (Silver Spring). 2010;18:55-62 pubmed publisher
Thabuis C, Tissot Favre D, Bezelgues J, Martin J, Cruz Hernandez C, Dionisi F, et al. Biological functions and metabolism of oleoylethanolamide. Lipids. 2008;43:887-94 pubmed publisher
Moise A, Eisenstein S, Astarita G, Piomelli D, Hohmann A. An endocannabinoid signaling system modulates anxiety-like behavior in male Syrian hamsters. Psychopharmacology (Berl). 2008;200:333-46 pubmed publisher
Houben E, Hachem J, De Paepe K, Rogiers V. Epidermal ceramidase activity regulates epidermal desquamation via stratum corneum acidification. Skin Pharmacol Physiol. 2008;21:111-8 pubmed publisher
Wang J, Ueda N. Role of the endocannabinoid system in metabolic control. Curr Opin Nephrol Hypertens. 2008;17:1-10 pubmed
Wise L, Cannavacciulo R, Cravatt B, Martin B, Lichtman A. Evaluation of fatty acid amides in the carrageenan-induced paw edema model. Neuropharmacology. 2008;54:181-8 pubmed
Suardiaz M, Estivill Torrus G, Goicoechea C, Bilbao A, Rodriguez de Fonseca F. Analgesic properties of oleoylethanolamide (OEA) in visceral and inflammatory pain. Pain. 2007;133:99-110 pubmed
Schreiber D, Harlfinger S, Nolden B, Gerth C, Jaehde U, Schömig E, et al. Determination of anandamide and other fatty acyl ethanolamides in human serum by electrospray tandem mass spectrometry. Anal Biochem. 2007;361:162-8 pubmed
Grijalvo S, Bedia C, Triola G, Casas J, Llebaria A, Teixidó J, et al. Design, synthesis and activity as acid ceramidase inhibitors of 2-oxooctanoyl and N-oleoylethanolamine analogues. Chem Phys Lipids. 2006;144:69-84 pubmed
Llacuna L, Mari M, Garcia Ruiz C, Fernandez Checa J, Morales A. Critical role of acidic sphingomyelinase in murine hepatic ischemia-reperfusion injury. Hepatology. 2006;44:561-72 pubmed
Tripathy S, Kleppinger Sparace K, Dixon R, Chapman K. N-acylethanolamine signaling in tobacco is mediated by a membrane-associated, high-affinity binding protein. Plant Physiol. 2003;131:1781-91 pubmed
Hofmann U, Domeier E, Frantz S, Laser M, Weckler B, Kuhlencordt P, et al. Increased myocardial oxygen consumption by TNF-alpha is mediated by a sphingosine signaling pathway. Am J Physiol Heart Circ Physiol. 2003;284:H2100-5 pubmed
Lecour S, Smith R, Woodward B, Opie L, Rochette L, Sack M. Identification of a novel role for sphingolipid signaling in TNF alpha and ischemic preconditioning mediated cardioprotection. J Mol Cell Cardiol. 2002;34:509-18 pubmed
Amadou A, Nawrocki A, Best Belpomme M, Pavoine C, Pecker F. Arachidonic acid mediates dual effect of TNF-alpha on Ca2+ transients and contraction of adult rat cardiomyocytes. Am J Physiol Cell Physiol. 2002;282:C1339-47 pubmed
product information
Catalog Number :
O0383
Product Name :
N-Oleoylethanolamine
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
~98% (TLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA