This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Nuclease micrococcal from Staphylococcus aureus
catalog :
N5386
citations: 63
Reference
Murawska M, Schauer T, Matsuda A, Wilson M, Pysik T, Wojcik F, et al. The Chaperone FACT and Histone H2B Ubiquitination Maintain S. pombe Genome Architecture through Genic and Subtelomeric Functions. Mol Cell. 2020;77:501-513.e7 pubmed publisher
Fingerhut L, Ohnesorge B, von Borstel M, Schumski A, Strutzberg Minder K, Morgelin M, et al. Neutrophil Extracellular Traps in the Pathogenesis of Equine Recurrent Uveitis (ERU). Cells. 2019;8: pubmed publisher
Donovan B, Huynh A, Ball D, Patel H, Poirier M, Larson D, et al. Live-cell imaging reveals the interplay between transcription factors, nucleosomes, and bursting. EMBO J. 2019;38: pubmed publisher
Rao R, Ketkar A, Kedia N, Krishnamoorthy V, Lakshmanan V, Kumar P, et al. KMT1 family methyltransferases regulate heterochromatin-nuclear periphery tethering via histone and non-histone protein methylation. EMBO Rep. 2019;20: pubmed publisher
Saleh R, Dilg D, Abou Zeid A, Hashad D, Scambler P, Chapgier A. HIRA directly targets the enhancers of selected cardiac transcription factors during in vitro differentiation of mouse embryonic stem cells. Mol Biol Rep. 2018;45:1001-1011 pubmed publisher
Li H, Yao Q, Mariscal A, Wu X, Hulse J, Pedersen E, et al. Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation. Nat Commun. 2018;9:1420 pubmed publisher
Manterola M, Brown T, Oh M, Garyn C, Gonzalez B, Wolgemuth D. BRDT is an essential epigenetic regulator for proper chromatin organization, silencing of sex chromosomes and crossover formation in male meiosis. PLoS Genet. 2018;14:e1007209 pubmed publisher
Truong D, Boeke J. Resetting the Yeast Epigenome with Human Nucleosomes. Cell. 2017;171:1508-1519.e13 pubmed publisher
Zou B, Sun Q, Zhang W, DING Y, Yang D, Shi Z, et al. The Arabidopsis Chromatin-Remodeling Factor CHR5 Regulates Plant Immune Responses and Nucleosome Occupancy. Plant Cell Physiol. 2017;58:2202-2216 pubmed publisher
Zhao H, Zhu X, Wang K, Gent J, Zhang W, Dawe R, et al. Gene Expression and Chromatin Modifications Associated with Maize Centromeres. G3 (Bethesda). 2015;6:183-92 pubmed publisher
Kocyłowski M, Rey A, Stewart G, Halazonetis T. Ubiquitin-H2AX fusions render 53BP1 recruitment to DNA damage sites independent of RNF8 or RNF168. Cell Cycle. 2015;14:1748-58 pubmed publisher
Thomas C, Kotova E, Andrake M, Adolf Bryfogle J, Glaser R, Regnard C, et al. Kinase-mediated changes in nucleosome conformation trigger chromatin decondensation via poly(ADP-ribosyl)ation. Mol Cell. 2014;53:831-42 pubmed publisher
Hernandez F, Huang L, Olson M, Powers K, Hernandez L, Meyerholz D, et al. Noninvasive imaging of Staphylococcus aureus infections with a nuclease-activated probe. Nat Med. 2014;20:301-6 pubmed publisher
Douglas K, Wang X, Jasti M, Wolff A, Vandeberg J, Clark A, et al. Genome-wide histone state profiling of fibroblasts from the opossum, Monodelphis domestica, identifies the first marsupial-specific imprinted gene. BMC Genomics. 2014;15:89 pubmed publisher
Zhang T, Talbert P, Zhang W, Wu Y, Yang Z, Henikoff J, et al. The CentO satellite confers translational and rotational phasing on cenH3 nucleosomes in rice centromeres. Proc Natl Acad Sci U S A. 2013;110:E4875-83 pubmed publisher
Ichikawa Y, Morohashi N, Nishimura Y, Kurumizaka H, Shimizu M. Telomeric repeats act as nucleosome-disfavouring sequences in vivo. Nucleic Acids Res. 2014;42:1541-52 pubmed publisher
Krajewski W. Comparison of the Isw1a, Isw1b, and Isw2 nucleosome disrupting activities. Biochemistry. 2013;52:6940-9 pubmed publisher
Shebzukhov Y, Horn K, Brazhnik K, Drutskaya M, Kuchmiy A, Kuprash D, et al. Dynamic changes in chromatin conformation at the TNF transcription start site in T helper lymphocyte subsets. Eur J Immunol. 2014;44:251-64 pubmed publisher
Roche J, Dellarole M, Caro J, Norberto D, Garcia A, Garcia Moreno B, et al. Effect of internal cavities on folding rates and routes revealed by real-time pressure-jump NMR spectroscopy. J Am Chem Soc. 2013;135:14610-8 pubmed publisher
Mizukami T, Xu M, Cheng H, Roder H, Maki K. Nonuniform chain collapse during early stages of staphylococcal nuclease folding detected by fluorescence resonance energy transfer and ultrarapid mixing methods. Protein Sci. 2013;22:1336-48 pubmed publisher
Spencer D, Bertrand G, Stites W. The pH dependence of staphylococcal nuclease stability is incompatible with a three-state denaturation model. Biophys Chem. 2013;180-181:86-94 pubmed publisher
Tang J, Chen J, Li H, Zeng P, Li J. Characterization of adhesin genes, staphylococcal nuclease, hemolysis, and biofilm formation among Staphylococcus aureus strains isolated from different sources. Foodborne Pathog Dis. 2013;10:757-63 pubmed publisher
Dellarole M, Kobayashi K, Rouget J, Caro J, Roche J, Islam M, et al. Probing the physical determinants of thermal expansion of folded proteins. J Phys Chem B. 2013;117:12742-9 pubmed publisher
González Prieto R, Muñoz Cabello A, Cabello Lobato M, Prado F. Rad51 replication fork recruitment is required for DNA damage tolerance. EMBO J. 2013;32:1307-21 pubmed publisher
Armstrong A, Hildreth J, Amzel L. Structural and thermodynamic insights into the recognition of native proteins by anti-peptide antibodies. J Mol Biol. 2013;425:2027-2038 pubmed publisher
Nikitina T, Wang D, Gomberg M, Grigoryev S, Zhurkin V. Combined micrococcal nuclease and exonuclease III digestion reveals precise positions of the nucleosome core/linker junctions: implications for high-resolution nucleosome mapping. J Mol Biol. 2013;425:1946-1960 pubmed publisher
Xie T, Feng Y, Shan L, Wang J. Modeling of the [E43S]SNase-ssDNA-Cd(2+) complex: structural insight into the action of nuclease on ssDNA. Arch Biochem Biophys. 2013;532:103-13 pubmed publisher
Olson M, Nygaard T, Ackermann L, Watkins R, Zurek O, Pallister K, et al. Staphylococcus aureus nuclease is an SaeRS-dependent virulence factor. Infect Immun. 2013;81:1316-24 pubmed publisher
Phetrungnapha A, Panyim S, Ongvarrasopone C. Penaeus monodon Tudor staphylococcal nuclease preferentially interacts with N-terminal domain of Argonaute-1. Fish Shellfish Immunol. 2013;34:875-84 pubmed publisher
Rodriguez J, Tsukiyama T. ATR-like kinase Mec1 facilitates both chromatin accessibility at DNA replication forks and replication fork progression during replication stress. Genes Dev. 2013;27:74-86 pubmed publisher
Redel H, Gao Z, Li H, Alekseyenko A, Zhou Y, Perez Perez G, et al. Quantitation and composition of cutaneous microbiota in diabetic and nondiabetic men. J Infect Dis. 2013;207:1105-14 pubmed publisher
Hu Y, Meng J, Shi C, Hervin K, Fratamico P, Shi X. Characterization and comparative analysis of a second thermonuclease from Staphylococcus aureus. Microbiol Res. 2013;168:174-82 pubmed publisher
Tunsjø H, Follin Arbelet B, Clausen N, Ness Y, Leegaard T, Bemanian V. A rapid, high-throughput screening method for carriage of methicillin-resistant Staphylococcus aureus. APMIS. 2013;121:865-70 pubmed publisher
de Vries S, Naarmann de Vries I, Urlaub H, Lue H, Bernhagen J, Ostareck D, et al. Identification of DEAD-box RNA helicase 6 (DDX6) as a cellular modulator of vascular endothelial growth factor expression under hypoxia. J Biol Chem. 2013;288:5815-27 pubmed publisher
Kim B, Park J, Song C, Kim J, Lim H, Lee H, et al. Clarifying the transmission route of Staphylococcus aureus colonizing the skin in early childhood atopic dermatitis. Ann Allergy Asthma Immunol. 2012;109:448-53 pubmed publisher
Gaffney D, McVicker G, Pai A, Fondufe Mittendorf Y, Lewellen N, Michelini K, et al. Controls of nucleosome positioning in the human genome. PLoS Genet. 2012;8:e1003036 pubmed publisher
Lee K, Lau Z, Meredith C, Park J. Decrease of p400 ATPase complex and loss of H2A.Z within the p21 promoter occur in senescent IMR-90 human fibroblasts. Mech Ageing Dev. 2012;133:686-94 pubmed publisher
Rosenberg Goldstein R, Micallef S, Gibbs S, Davis J, He X, George A, et al. Methicillin-resistant Staphylococcus aureus (MRSA) detected at four U.S. wastewater treatment plants. Environ Health Perspect. 2012;120:1551-8 pubmed publisher
Ng D, Sarkar C. Engineering signal peptides for enhanced protein secretion from Lactococcus lactis. Appl Environ Microbiol. 2013;79:347-56 pubmed publisher
Roche J, Dellarole M, Caro J, Guca E, Norberto D, Yang Y, et al. Remodeling of the folding free energy landscape of staphylococcal nuclease by cavity-creating mutations. Biochemistry. 2012;51:9535-46 pubmed publisher
Molla B, Byrne M, Abley M, Mathews J, Jackson C, Fedorka Cray P, et al. Epidemiology and genotypic characteristics of methicillin-resistant Staphylococcus aureus strains of porcine origin. J Clin Microbiol. 2012;50:3687-93 pubmed publisher
Milla M, Daban J. Self-assembly of thin plates from micrococcal nuclease-digested chromatin of metaphase chromosomes. Biophys J. 2012;103:567-75 pubmed publisher
Pogany J, Nagy P. p33-Independent activation of a truncated p92 RNA-dependent RNA polymerase of Tomato bushy stunt virus in yeast cell-free extract. J Virol. 2012;86:12025-38 pubmed publisher
Wei G, Hu G, Cui K, Zhao K. Genome-wide mapping of nucleosome occupancy, histone modifications, and gene expression using next-generation sequencing technology. Methods Enzymol. 2012;513:297-313 pubmed publisher
Wal M, Pugh B. Genome-wide mapping of nucleosome positions in yeast using high-resolution MNase ChIP-Seq. Methods Enzymol. 2012;513:233-50 pubmed publisher
Krietenstein N, Wippo C, Lieleg C, Korber P. Genome-wide in vitro reconstitution of yeast chromatin with in vivo-like nucleosome positioning. Methods Enzymol. 2012;513:205-32 pubmed publisher
Cole H, Howard B, Clark D. Genome-wide mapping of nucleosomes in yeast using paired-end sequencing. Methods Enzymol. 2012;513:145-68 pubmed publisher
Ohmayer U, Pérez Fernández J, Hierlmeier T, Pöll G, Williams L, Griesenbeck J, et al. Local tertiary structure probing of ribonucleoprotein particles by nuclease fusion proteins. PLoS ONE. 2012;7:e42449 pubmed publisher
Chen Y, Wang L, Jiang W. Micrococcal nuclease detection based on peptide-bridged energy transfer between quantum dots and dye-labeled DNA. Talanta. 2012;97:533-8 pubmed publisher
Majumder P, Dasgupta D. Effect of DNA groove binder distamycin A upon chromatin structure. PLoS ONE. 2011;6:e26486 pubmed publisher
Celona B, Weiner A, Di Felice F, Mancuso F, Cesarini E, Rossi R, et al. Substantial histone reduction modulates genomewide nucleosomal occupancy and global transcriptional output. PLoS Biol. 2011;9:e1001086 pubmed publisher
Lorch Y, Griesenbeck J, Boeger H, Maier Davis B, Kornberg R. Selective removal of promoter nucleosomes by the RSC chromatin-remodeling complex. Nat Struct Mol Biol. 2011;18:881-5 pubmed publisher
Chung H, Dunkel I, Heise F, Linke C, Krobitsch S, Ehrenhofer Murray A, et al. The effect of micrococcal nuclease digestion on nucleosome positioning data. PLoS ONE. 2010;5:e15754 pubmed publisher
Shipp L, Lee J, Yu C, Pufall M, Zhang P, Scott D, et al. Transcriptional regulation of human dual specificity protein phosphatase 1 (DUSP1) gene by glucocorticoids. PLoS ONE. 2010;5:e13754 pubmed publisher
Bendaly J, Doll M, Millner L, Metry K, Smith N, Pierce W, et al. Differences between human slow N-acetyltransferase 2 alleles in levels of 4-aminobiphenyl-induced DNA adducts and mutations. Mutat Res. 2009;671:13-9 pubmed publisher
Zhu X, Gustafsson C. Distinct differences in chromatin structure at subtelomeric X and Y' elements in budding yeast. PLoS ONE. 2009;4:e6363 pubmed publisher
Zawadzki K, Morozov A, Broach J. Chromatin-dependent transcription factor accessibility rather than nucleosome remodeling predominates during global transcriptional restructuring in Saccharomyces cerevisiae. Mol Biol Cell. 2009;20:3503-13 pubmed publisher
Brand M, Rampalli S, Chaturvedi C, Dilworth F. Analysis of epigenetic modifications of chromatin at specific gene loci by native chromatin immunoprecipitation of nucleosomes isolated using hydroxyapatite chromatography. Nat Protoc. 2008;3:398-409 pubmed publisher
Sivasubramaniam S, Sun X, Pan Y, Wang S, Lee E. Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1. Genes Dev. 2008;22:587-600 pubmed publisher
Gilfillan S, Stelzer G, Piaia E, Hofmann M, Meisterernst M. Efficient binding of NC2.TATA-binding protein to DNA in the absence of TATA. J Biol Chem. 2005;280:6222-30 pubmed
Lee D, Hwang S, Kim J, Choe J. Functional interaction between p/CAF and human papillomavirus E2 protein. J Biol Chem. 2002;277:6483-9 pubmed
Sulkowski E, Laskowski M. Phosphatase-free crystalline micrococcal nuclease. J Biol Chem. 1966;241:4386-8 pubmed
Kacian D, Spiegelman S. Use of micrococcal nuclease to monitor hybridization reactions with DNA. Anal Biochem. 1974;58:534-40 pubmed
product information
Catalog Number :
N5386
Product Name :
Nuclease micrococcal from Staphylococcus aureus
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
100-300 units/mg protein
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA