This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
19-Norethindrone
catalog :
N4128
citations: 61
Reference
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Redd A. Research on hormonal contraception and HIV. Lancet. 2014;383:305 pubmed publisher
GOLLUB E, Stein Z. Research on hormonal contraception and HIV. Lancet. 2014;383:304-5 pubmed publisher
Cates W. Research on hormonal contraception and HIV. Lancet. 2014;383:303-4 pubmed publisher
Kogan P, Wald M. Male contraception: history and development. Urol Clin North Am. 2014;41:145-61 pubmed publisher
Crean C, Tompson D, Buraglio M. The effect of ezogabine on the pharmacokinetics of an oral contraceptive agent. Int J Clin Pharmacol Ther. 2013;51:847-53 pubmed publisher
Archer D, Nakajima S, Sawyer A, Wentworth J, Trupin S, Koltun W, et al. Norethindrone acetate 1.0 milligram and ethinyl estradiol 10 micrograms as an ultra low-dose oral contraceptive. Obstet Gynecol. 2013;122:601-7 pubmed publisher
Polis C, Curtis K. Use of hormonal contraceptives and HIV acquisition in women: a systematic review of the epidemiological evidence. Lancet Infect Dis. 2013;13:797-808 pubmed publisher
Ralph L, McCoy S, Hallett T, Padian N. Next steps for research on hormonal contraception and HIV. Lancet. 2013;382:1467-9 pubmed publisher
Africander D, Louw R, Hapgood J. Investigating the anti-mineralocorticoid properties of synthetic progestins used in hormone therapy. Biochem Biophys Res Commun. 2013;433:305-10 pubmed publisher
Juvkam K, Gudim H. [Drug induced displacement of menstruation]. Tidsskr Nor Laegeforen. 2013;133:166-8 pubmed publisher
Bush M, Scott R, Watanalumlerd P, Zhi H, Lewis E. Effects of multiple doses of albiglutide on the pharmacokinetics, pharmacodynamics, and safety of digoxin, warfarin, or a low-dose oral contraceptive. Postgrad Med. 2012;124:55-72 pubmed publisher
Polisseni A, Andrade A, Ribeiro L, Castro I, Brandão M, Polisseni F, et al. Effects of a continuous-combined regimen of low-dose hormone therapy (oestradiol and norethindrone acetate) and tibolone on the quality of life in symptomatic postmenopausal women: a double-blind, randomised study. Maturitas. 2013;74:172-8 pubmed publisher
Roach R, Lijfering W, Helmerhorst F, Cannegieter S, Rosendaal F, Van Hylckama Vlieg A. The risk of venous thrombosis in women over 50 years old using oral contraception or postmenopausal hormone therapy. J Thromb Haemost. 2013;11:124-31 pubmed publisher
Demeestere I, Brice P, Peccatori F, Kentos A, Gaillard I, Zachee P, et al. Gonadotropin-releasing hormone agonist for the prevention of chemotherapy-induced ovarian failure in patients with lymphoma: 1-year follow-up of a prospective randomized trial. J Clin Oncol. 2013;31:903-9 pubmed publisher
Połać I, Borowiecka M, Wilamowska A, Nowak P. Coagulation and fibrynolitic parameters in women and the effects of hormone therapy; comparison of transdermal and oral administration. Gynecol Endocrinol. 2013;29:165-8 pubmed publisher
Schneck H, Ruan X, Seeger H, Cahill M, Fehm T, Mueck A, et al. Membrane-receptor initiated proliferative effects of dienogest in human breast cancer cells. Gynecol Endocrinol. 2013;29:160-3 pubmed publisher
Fetherston S, Geer L, Veazey R, Goldman L, Murphy D, Ketas T, et al. Partial protection against multiple RT-SHIV162P3 vaginal challenge of rhesus macaques by a silicone elastomer vaginal ring releasing the NNRTI MC1220. J Antimicrob Chemother. 2013;68:394-403 pubmed publisher
LoRusso P, Piha Paul S, Mita M, Colevas A, Malhi V, Colburn D, et al. Co-administration of vismodegib with rosiglitazone or combined oral contraceptive in patients with locally advanced or metastatic solid tumors: a pharmacokinetic assessment of drug-drug interaction potential. Cancer Chemother Pharmacol. 2013;71:193-202 pubmed publisher
Ferrero S, Leone Roberti Maggiore U, Scala C, Di Luca M, Venturini P, Remorgida V. Changes in the size of rectovaginal endometriotic nodules infiltrating the rectum during hormonal therapies. Arch Gynecol Obstet. 2013;287:447-53 pubmed publisher
Schierbeck L, Rejnmark L, Tofteng C, Stilgren L, Eiken P, Mosekilde L, et al. Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomised trial. BMJ. 2012;345:e6409 pubmed publisher
Brosnan J, Sheppard B, Kelly L, O Leary J, Norris L. Norethisterone acetate alters coagulation gene expression in vitro in human cell culture. Thromb Res. 2013;131:72-7 pubmed publisher
van den Broeck K, Janssens D, Defoort P. A forgotten founding father of the Pill: Ferdinand Peeters, MD. Eur J Contracept Reprod Health Care. 2012;17:321-8 pubmed publisher
Minami T, Kosugi K, Suganuma I, Yamanaka K, Kusuki I, Oyama T, et al. Antiproliferative and apoptotic effects of norethisterone on endometriotic stromal cells in vitro. Eur J Obstet Gynecol Reprod Biol. 2013;166:76-80 pubmed publisher
Vercellini P, Somigliana E, Consonni D, Frattaruolo M, De Giorgi O, Fedele L. Surgical versus medical treatment for endometriosis-associated severe deep dyspareunia: I. Effect on pain during intercourse and patient satisfaction. Hum Reprod. 2012;27:3450-9 pubmed publisher
Jonusiene G, Zilaitiene B, Adomaitiene V, Aniuliene R, Bancroft J. Sexual function, mood and menopause symptoms in Lithuanian postmenopausal women. Climacteric. 2013;16:185-93 pubmed publisher
Manassiev N, Godsland I, Proudler A, Whitehead M, Stevenson J. Effects of tibolone or continuous combined oestradiol/norethisterone acetate on glucose and insulin metabolism. Clin Endocrinol (Oxf). 2013;78:297-302 pubmed publisher
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Mansour D. Safer prescribing of therapeutic norethisterone for women at risk of venous thromboembolism. J Fam Plann Reprod Health Care. 2012;38:148-9 pubmed publisher
Steward R, Melamed A, Granat A, Mishell D. Comparison of cervical mucus of 24/4 vs. 21/7 combined oral contraceptives. Contraception. 2012;86:710-5 pubmed publisher
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Koskela Niska V, Lyytinen H, Riska A, Pukkala E, Ylikorkala O. Ovarian cancer risk in postmenopausal women using estradiol-progestin therapy - a nationwide study. Climacteric. 2013;16:48-53 pubmed publisher
Chwalisz K, Surrey E, Stanczyk F. The hormonal profile of norethindrone acetate: rationale for add-back therapy with gonadotropin-releasing hormone agonists in women with endometriosis. Reprod Sci. 2012;19:563-71 pubmed publisher
Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W. Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS Comput Biol. 2011;7:e1002310 pubmed publisher
Ekins S, Williams A, Xu J. A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug Metab Dispos. 2010;38:2302-8 pubmed publisher
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Fourches D, Barnes J, Day N, Bradley P, Reed J, Tropsha A. Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chem Res Toxicol. 2010;23:171-83 pubmed publisher
Paulen M, Curtis K. When can a woman have repeat progestogen-only injectables--depot medroxyprogesterone acetate or norethisterone enantate?. Contraception. 2009;80:391-408 pubmed publisher
Rajput R, Dhuan J, Agarwal S, Gahlaut P. Central venous sinus thrombosis in a young woman taking norethindrone acetate for dysfunctional uterine bleeding: case report and review of literature. J Obstet Gynaecol Can. 2008;30:680-683 pubmed publisher
Casey C, Murray C. HT update: spotlight on estradiol/norethindrone acetate combination therapy. Clin Interv Aging. 2008;3:9-16 pubmed
Cherkasov A, Ban F, Santos Filho O, Thorsteinson N, Fallahi M, Hammond G. An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin. J Med Chem. 2008;51:2047-56 pubmed publisher
Moda T, Montanari C, Andricopulo A. Hologram QSAR model for the prediction of human oral bioavailability. Bioorg Med Chem. 2007;15:7738-45 pubmed
Draper B, Morroni C, Hoffman M, Smit J, Beksinska M, Hapgood J, et al. Depot medroxyprogesterone versus norethisterone oenanthate for long-acting progestogenic contraception. Cochrane Database Syst Rev. 2006;:CD005214 pubmed
Lill M, Winiger F, Vedani A, Ernst B. Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. J Med Chem. 2005;48:5666-74 pubmed
Riis B, Lehmann H, Christiansen C. Norethisterone acetate in combination with estrogen: effects on the skeleton and other organs. A review. Am J Obstet Gynecol. 2002;187:1101-16 pubmed
Maier W, Herman J. Pharmacology and toxicology of ethinyl estradiol and norethindrone acetate in experimental animals. Regul Toxicol Pharmacol. 2001;34:53-61 pubmed
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Wiseman L, McTavish D. Transdermal estradiol/norethisterone. A review of its pharmacological properties and clinical use in postmenopausal women. Drugs Aging. 1994;4:238-56 pubmed
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Stanczyk F, Roy S. Metabolism of levonorgestrel, norethindrone, and structurally related contraceptive steroids. Contraception. 1990;42:67-96 pubmed
product information
Catalog Number :
N4128
Product Name :
19-Norethindrone
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98%, powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA