This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Naltrexone hydrochloride
catalog :
N3136
citations: 24
Reference
Katner S, Bredhold K, Steagall K, Bell R, Neal Beliveau B, Cheong M, et al. Caenorhabditis elegans as a model system to identify therapeutics for alcohol use disorders. Behav Brain Res. 2019;365:7-16 pubmed publisher
Floettmann E, Bui K, Sostek M, Payza K, Eldon M. Pharmacologic Profile of Naloxegol, a Peripherally Acting µ-Opioid Receptor Antagonist, for the Treatment of Opioid-Induced Constipation. J Pharmacol Exp Ther. 2017;361:280-291 pubmed publisher
Cai Y, Yang L, Hu G, Chen X, Niu F, Yuan L, et al. Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy. J Cell Biol. 2016;215:245-258 pubmed
Kaufling J, Aston Jones G. Persistent Adaptations in Afferents to Ventral Tegmental Dopamine Neurons after Opiate Withdrawal. J Neurosci. 2015;35:10290-303 pubmed publisher
Moreno Vicente R, Fernández Nieva Z, Navarro A, Gascón Crespí I, Farré Albaladejo M, Igartua M, et al. Development and validation of a bioanalytical method for the simultaneous determination of heroin, its main metabolites, naloxone and naltrexone by LC-MS/MS in human plasma samples: Application to a clinical trial of oral administration of a heroin/n. J Pharm Biomed Anal. 2015;114:105-12 pubmed publisher
Verplaetse T, Czachowski C. Low-dose prazosin alone and in combination with propranolol or naltrexone: effects on ethanol and sucrose seeking and self-administration in the P rat. Psychopharmacology (Berl). 2015;232:2647-57 pubmed publisher
Miranda H, Sierralta F, Lux S, Troncoso R, Ciudad N, Zepeda R, et al. Involvement of nitridergic and opioidergic pathways in the antinociception of gabapentin in the orofacial formalin test in mice. Pharmacol Rep. 2015;67:399-403 pubmed publisher
Xu J, Zhao Q, Wei L, Yang Y, Xu R, Yu N, et al. Phytochemical composition and antinociceptive activity of Bauhinia glauca subsp. hupehana in rats. PLoS ONE. 2015;10:e0117801 pubmed publisher
Chumakov I, Milet A, Cholet N, Primas G, Boucard A, Pereira Y, et al. Polytherapy with a combination of three repurposed drugs (PXT3003) down-regulates Pmp22 over-expression and improves myelination, axonal and functional parameters in models of CMT1A neuropathy. Orphanet J Rare Dis. 2014;9:201 pubmed publisher
Abdelkader H, Pierscionek B, Alany R. Novel in situ gelling ocular films for the opioid growth factor-receptor antagonist-naltrexone hydrochloride: fabrication, mechanical properties, mucoadhesion, tolerability and stability studies. Int J Pharm. 2014;477:631-42 pubmed publisher
Sanchez Roige S, Ripley T, Stephens D. Alleviating waiting impulsivity and perseverative responding by μ-opioid receptor antagonism in two inbred mouse strains. Psychopharmacology (Berl). 2015;232:1483-92 pubmed publisher
Qiu Y, He X, Zhang Y, Li J. Discriminative stimulus effects of the novel imidazoline Iâ‚‚ receptor ligand CR4056 in rats. Sci Rep. 2014;4:6605 pubmed publisher
Avena N, Bocarsly M, Murray S, Gold M. Effects of baclofen and naltrexone, alone and in combination, on the consumption of palatable food in male rats. Exp Clin Psychopharmacol. 2014;22:460-7 pubmed publisher
Gassaway M, Rives M, Kruegel A, Javitch J, Sames D. The atypical antidepressant and neurorestorative agent tianeptine is a μ-opioid receptor agonist. Transl Psychiatry. 2014;4:e411 pubmed publisher
Ciccocioppo R, Stopponi S, Economidou D, Kuriyama M, Kinoshita H, Heilig M, et al. Chronic treatment with novel brain-penetrating selective NOP receptor agonist MT-7716 reduces alcohol drinking and seeking in the rat. Neuropsychopharmacology. 2014;39:2601-10 pubmed publisher
Norwood A, Al Chaer E, Fantegrossi W. Predisposing effects of neonatal visceral pain on abuse-related effects of morphine in adult male Sprague Dawley rats. Psychopharmacology (Berl). 2014;231:4281-9 pubmed publisher
Wright F, Rodgers R. Behavioural profile of exendin-4/naltrexone dose combinations in male rats during tests of palatable food consumption. Psychopharmacology (Berl). 2014;231:3729-44 pubmed publisher
Hofmann T, Schafer S, Linseisen M, Sytik L, Gudermann T, Chubanov V. Activation of TRPM7 channels by small molecules under physiological conditions. Pflugers Arch. 2014;466:2177-89 pubmed publisher
Cordery S, Taverner A, Ridzwan I, Guy R, Delgado Charro M, Husbands S, et al. A non-rewarding, non-aversive buprenorphine/naltrexone combination attenuates drug-primed reinstatement to cocaine and morphine in rats in a conditioned place preference paradigm. Addict Biol. 2014;19:575-86 pubmed publisher
Zagon I, Klocek M, Sassani J, McLaughlin P. Dry eye reversal and corneal sensation restoration with topical naltrexone in diabetes mellitus. Arch Ophthalmol. 2009;127:1468-73 pubmed publisher
Yuan J, Johnson R, Huang R, Wichterman J, Jiang H, Hayton K, et al. Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nat Chem Biol. 2009;5:765-71 pubmed publisher
Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed
Powell K, Holtzman S. Differential antagonism of the rate-decreasing effects of kappa-opioid receptor agonists by naltrexone and norbinaltorphimine. Eur J Pharmacol. 1999;377:21-8 pubmed
Bienkowski P, Kostowski W, Koros E. Ethanol-reinforced behaviour in the rat: effects of naltrexone. Eur J Pharmacol. 1999;374:321-7 pubmed
product information
Catalog Number :
N3136
Product Name :
Naltrexone hydrochloride
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA