This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
PYR-41
catalog :
N2915
citations: 29
Reference
Franklin T, Pruneda J. A High-Throughput Assay for Monitoring Ubiquitination in Real Time. Front Chem. 2019;7:816 pubmed publisher
Engström P, Burke T, Mitchell G, Ingabire N, Mark K, Golovkine G, et al. Evasion of autophagy mediated by Rickettsia surface protein OmpB is critical for virulence. Nat Microbiol. 2019;4:2538-2551 pubmed publisher
Wu Y, Doepner M, Hojnacki T, Feng Z, Katona B, He X, et al. Disruption of the menin-MLL interaction triggers menin protein degradation via ubiquitin-proteasome pathway. Am J Cancer Res. 2019;9:1682-1694 pubmed
Manohar S, Jacob S, WANG J, Wiechecki K, Koh H, Simões V, et al. Polyubiquitin Chains Linked by Lysine Residue 48 (K48) Selectively Target Oxidized Proteins In Vivo. Antioxid Redox Signal. 2019;31:1133-1149 pubmed publisher
Piersma S, Pak Wittel M, Lin A, Plougastel Douglas B, Yokoyama W. Activation Receptor-Dependent IFN-γ Production by NK Cells Is Controlled by Transcription, Translation, and the Proteasome. J Immunol. 2019;203:1981-1988 pubmed publisher
Madigan V, Yuziuk J, Chiarella A, Tyson T, Meganck R, Elmore Z, et al. Ring finger protein 121 is a potent regulator of adeno-associated viral genome transcription. PLoS Pathog. 2019;15:e1007988 pubmed publisher
Zachari M, Gudmundsson S, Li Z, Manifava M, Shah R, Smith M, et al. Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform. Dev Cell. 2019;50:627-643.e5 pubmed publisher
Arashiki N, Niitsuma K, Seki M, Takakuwa Y, Nakamura F. ATP11C T418N, a gene mutation causing congenital hemolytic anemia, reduces flippase activity due to improper membrane trafficking. Biochem Biophys Res Commun. 2019;516:705-712 pubmed publisher
Chitiprolu M, Jagow C, Tremblay V, Bondy Chorney E, Paris G, Savard A, et al. A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy. Nat Commun. 2018;9:2794 pubmed publisher
Surve M, Bhutda S, Datey A, Anil A, Rawat S, Pushpakaran A, et al. Heterogeneity in pneumolysin expression governs the fate of Streptococcus pneumoniae during blood-brain barrier trafficking. PLoS Pathog. 2018;14:e1007168 pubmed publisher
Matsuo S, Chaung A, Liou D, Wang P, Yang W. Inhibition of ubiquitin-activating enzyme protects against organ injury after intestinal ischemia-reperfusion. Am J Physiol Gastrointest Liver Physiol. 2018;315:G283-G292 pubmed publisher
Carrier M, Lutzing R, Gaouar S, Rochette Egly C. TRIM24 mediates the interaction of the retinoic acid receptor alpha with the proteasome. FEBS Lett. 2018;592:1426-1433 pubmed publisher
Li P, Jiang W, Yu Q, Liu W, Zhou P, Li J, et al. Ubiquitination and degradation of GBPs by a Shigella effector to suppress host defence. Nature. 2017;551:378-383 pubmed publisher
Sahu S, Tiwari N, Pataskar A, Zhuang Y, Borisova M, Diken M, et al. FBXO32 promotes microenvironment underlying epithelial-mesenchymal transition via CtBP1 during tumour metastasis and brain development. Nat Commun. 2017;8:1523 pubmed publisher
Huang C, Guo X, Zhao H, An R, Lian K, Zhang X, et al. Nicotine induces H9C2 cell apoptosis via Akt protein degradation. Mol Med Rep. 2017;16:6269-6275 pubmed publisher
Santarino I, Viegas M, Domingues N, Ribeiro A, Soares M, Vieira O. Involvement of the p62/NRF2 signal transduction pathway on erythrophagocytosis. Sci Rep. 2017;7:5812 pubmed publisher
Lei C, Wei Y, Tang H, Wen Q, Ye C, Zhang C, et al. PKC-α Triggers EGFR Ubiquitination, Endocytosis and ERK Activation in Podocytes Stimulated with High Glucose. Cell Physiol Biochem. 2017;42:281-294 pubmed publisher
Gulia R, Sharma R, Bhattacharyya S. A Critical Role for Ubiquitination in the Endocytosis of Glutamate Receptors. J Biol Chem. 2017;292:1426-1437 pubmed publisher
Gao M, Huang Z, Tao K, Xiao Q, Wang X, Cao W, et al. Depression of oncogenecity by dephosphorylating and degrading BCR-ABL. Oncotarget. 2017;8:3304-3314 pubmed publisher
Guo X, Yin H, Chen Y, Li L, Li J, Liu Q. TAK1 regulates caspase 8 activation and necroptotic signaling via multiple cell death checkpoints. Cell Death Dis. 2016;7:e2381 pubmed publisher
Hartz A, Zhong Y, Wolf A, LeVine H, Miller D, Bauer B. Aβ40 Reduces P-Glycoprotein at the Blood-Brain Barrier through the Ubiquitin-Proteasome Pathway. J Neurosci. 2016;36:1930-41 pubmed publisher
Qiu X, Fu Q, Meng C, Yu S, Zhan Y, Dong L, et al. Newcastle Disease Virus V Protein Targets Phosphorylated STAT1 to Block IFN-I Signaling. PLoS ONE. 2016;11:e0148560 pubmed publisher
Park J, Juhnn Y. cAMP signaling increases histone deacetylase 8 expression by inhibiting JNK-dependent degradation via autophagy and the proteasome system in H1299 lung cancer cells. Biochem Biophys Res Commun. 2016;470:336-342 pubmed publisher
Berry G, Asokan A. Chemical Modulation of Endocytic Sorting Augments Adeno-associated Viral Transduction. J Biol Chem. 2016;291:939-47 pubmed publisher
Ren J, Wu X, Jiang R, Hao D, Liu Y. Molecular hydrogen inhibits lipopolysaccharide-triggered NLRP3 inflammasome activation in macrophages by targeting the mitochondrial reactive oxygen species. Biochim Biophys Acta. 2016;1863:50-5 pubmed publisher
Asuthkar S, Velpula K, Elustondo P, Demirkhanyan L, Zakharian E. TRPM8 channel as a novel molecular target in androgen-regulated prostate cancer cells. Oncotarget. 2015;6:17221-36 pubmed
Ohshima K, Kanto K, Hatakeyama K, Ide T, Wakabayashi Nakao K, Watanabe Y, et al. Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Proteomics. 2014;14:2297-306 pubmed publisher
Bin B, Hojyo S, Hosaka T, Bhin J, Kano H, Miyai T, et al. Molecular pathogenesis of spondylocheirodysplastic Ehlers-Danlos syndrome caused by mutant ZIP13 proteins. EMBO Mol Med. 2014;6:1028-42 pubmed publisher
Molfetta R, Quatrini L, Capuano C, Gasparrini F, Zitti B, Zingoni A, et al. c-Cbl regulates MICA- but not ULBP2-induced NKG2D down-modulation in human NK cells. Eur J Immunol. 2014;44:2761-70 pubmed publisher
product information
Catalog Number :
N2915
Product Name :
PYR-41
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98% (HPLC), powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA