This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Nomifensine maleate salt
catalog :
N1530
citations: 32
Reference
Oh Y, Heien M, Park C, Kang Y, Kim J, Boschen S, et al. Tracking tonic dopamine levels in vivo using multiple cyclic square wave voltammetry. Biosens Bioelectron. 2018;121:174-182 pubmed publisher
Benleulmi Chaachoua A, Hegron A, Le Boulch M, Karamitri A, Wierzbicka M, Wong V, et al. Melatonin receptors limit dopamine reuptake by regulating dopamine transporter cell-surface exposure. Cell Mol Life Sci. 2018;75:4357-4370 pubmed publisher
Dunn M, Henke A, Clark S, Kovalyova Y, Kempadoo K, Karpowicz R, et al. Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo. Nat Commun. 2018;9:2838 pubmed publisher
Matthews A, He O, Buhusi M, Buhusi C. Dissociation of the role of the prelimbic cortex in interval timing and resource allocation: beneficial effect of norepinephrine and dopamine reuptake inhibitor nomifensine on anxiety-inducing distraction. Front Integr Neurosci. 2012;6:111 pubmed publisher
Guzmán Ramos K, Moreno Castilla P, Castro Cruz M, McGaugh J, Martinez Coria H, LaFerla F, et al. Restoration of dopamine release deficits during object recognition memory acquisition attenuates cognitive impairment in a triple transgenic mice model of Alzheimer's disease. Learn Mem. 2012;19:453-60 pubmed publisher
Mitch Taylor I, Jaquins Gerstl A, Sesack S, Michael A. Domain-dependent effects of DAT inhibition in the rat dorsal striatum. J Neurochem. 2012;122:283-94 pubmed publisher
Ferris M, Calipari E, Mateo Y, Melchior J, Roberts D, Jones S. Cocaine self-administration produces pharmacodynamic tolerance: differential effects on the potency of dopamine transporter blockers, releasers, and methylphenidate. Neuropsychopharmacology. 2012;37:1708-16 pubmed publisher
Poth L, O Connell B, McDermott J, Dluzen D. Nomifensine alters sex differences in striatal dopaminergic function. Synapse. 2012;66:686-93 pubmed publisher
Lundblad M, Decressac M, Mattsson B, Bjorklund A. Impaired neurotransmission caused by overexpression of ?-synuclein in nigral dopamine neurons. Proc Natl Acad Sci U S A. 2012;109:3213-9 pubmed publisher
Asensi Bernardi L, Martín Biosca Y, Sagrado S, Medina Hernández M. Electrokinetic chromatographic estimation of the enantioselective binding of nomifensine to human serum albumin and total plasma proteins. Biomed Chromatogr. 2012;26:1357-63 pubmed publisher
Kitanaka J, Kitanaka N, Hall F, Uhl G, Asano H, Chatani R, et al. Pretreatment with nomifensine or nomifensine analogue 4-phenyl-1,2,3,4-tetrahydroisoquinoline augments methamphetamine-induced stereotypical behavior in mice. Brain Res. 2012;1439:15-26 pubmed publisher
Lee H, Nakayama J, Xu Y, Fan X, Karouani M, Shen Y, et al. Dopamine dysregulation in a mouse model of paroxysmal nonkinesigenic dyskinesia. J Clin Invest. 2012;122:507-18 pubmed publisher
Stouffer M, Ali S, Reith M, Patel J, Sarti F, Carr K, et al. SKF-83566, a D1-dopamine receptor antagonist, inhibits the dopamine transporter. J Neurochem. 2011;118:714-20 pubmed publisher
Ulu S. Spectrofluorimetric determination of nomifensine in human plasma and urine by derivatization with fluorescamine. Luminescence. 2012;27:80-3 pubmed publisher
Borgkvist A, Malmlöf T, Feltmann K, Lindskog M, Schilström B. Dopamine in the hippocampus is cleared by the norepinephrine transporter. Int J Neuropsychopharmacol. 2012;15:531-40 pubmed publisher
Benoit Marand M, Ballion B, Borrelli E, Boraud T, Gonon F. Inhibition of dopamine uptake by D2 antagonists: an in vivo study. J Neurochem. 2011;116:449-58 pubmed publisher
Oyama G, Yoshimi K, Natori S, Chikaoka Y, Ren Y, Funayama M, et al. Impaired in vivo dopamine release in parkin knockout mice. Brain Res. 2010;1352:214-22 pubmed publisher
Walker Q, Morris S, Arrant A, Nagel J, PARYLAK S, Zhou G, et al. Dopamine uptake inhibitors but not dopamine releasers induce greater increases in motor behavior and extracellular dopamine in adolescent rats than in adult male rats. J Pharmacol Exp Ther. 2010;335:124-32 pubmed publisher
Getachew B, Hauser S, Taylor R, Tizabi Y. Alcohol-induced depressive-like behavior is associated with cortical norepinephrine reduction. Pharmacol Biochem Behav. 2010;96:395-401 pubmed publisher
Craft R, Kostick M, Rogers J, White C, Tsutsui K. Forced swim test behavior in postpartum rats. Pharmacol Biochem Behav. 2010;96:402-12 pubmed publisher
Yu J, Brown D, Burdette D. In vitro metabolism studies of nomifensine monooxygenation pathways: metabolite identification, reaction phenotyping, and bioactivation mechanism. Drug Metab Dispos. 2010;38:1767-78 pubmed publisher
Nikiforuk A, Popik P. Long-lasting cognitive deficit induced by stress is alleviated by acute administration of antidepressants. Psychoneuroendocrinology. 2011;36:28-39 pubmed publisher
Shiotsuki H, Yoshimi K, Shimo Y, Funayama M, Takamatsu Y, Ikeda K, et al. A rotarod test for evaluation of motor skill learning. J Neurosci Methods. 2010;189:180-5 pubmed publisher
Ferreira Nunes B, Duran R, Alfonso M, de Oliveira I, Ferreira Faro L. Evaluation of the effects and mechanisms of action of glufosinate, an organophosphate insecticide, on striatal dopamine release by using in vivo microdialysis in freely moving rats. Arch Toxicol. 2010;84:777-85 pubmed publisher
Hewett J, Johanson P, Sharma N, Standaert D, Balcioglu A. Function of dopamine transporter is compromised in DYT1 transgenic animal model in vivo. J Neurochem. 2010;113:228-35 pubmed publisher
Onogi H, Hozumi M, Nakagawasai O, Arai Y, Ishigaki S, Sato A, et al. Central administration of p-hydroxyamphetamine produces a behavioral stimulant effect in rodents: evidence for the involvement of dopaminergic systems. Psychopharmacology (Berl). 2010;208:323-31 pubmed publisher
Katz N, Guiard B, El Mansari M, Blier P. Effects of acute and sustained administration of the catecholamine reuptake inhibitor nomifensine on the firing activity of monoaminergic neurons. J Psychopharmacol. 2010;24:1223-35 pubmed publisher
Gruner J, Marcy V, Lin Y, Bozyczko Coyne D, Marino M, Gasior M. The roles of dopamine transport inhibition and dopamine release facilitation in wake enhancement and rebound hypersomnolence induced by dopaminergic agents. Sleep. 2009;32:1425-38 pubmed
Yu J, Mathisen D, Burdette D, Brown D, Becker C, Aharony D. Identification of multiple glutathione conjugates of 8-amino- 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline maleate (nomifensine) in liver microsomes and hepatocyte preparations: evidence of the bioactivation of nomifensine. Drug Metab Dispos. 2010;38:46-60 pubmed publisher
McDougall S, Reichel C, Farley C, Flesher M, Der Ghazarian T, Cortez A, et al. Postnatal manganese exposure alters dopamine transporter function in adult rats: Potential impact on nonassociative and associative processes. Neuroscience. 2008;154:848-60 pubmed publisher
Meiergerd S, Schenk J. Kinetic evaluation of the commonality between the site(s) of action of cocaine and some other structurally similar and dissimilar inhibitors of the striatal transporter for dopamine. J Neurochem. 1994;63:1683-92 pubmed
Wieczorek W, Kruk Z. A quantitative comparison on the effects of benztropine, cocaine and nomifensine on electrically evoked dopamine overflow and rate of re-uptake in the caudate putamen and nucleus accumbens in the rat brain slice. Brain Res. 1994;657:42-50 pubmed
product information
Catalog Number :
N1530
Product Name :
Nomifensine maleate salt
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA