This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Nucleoside 5′-Diphosphate Kinase from baker's yeast (S. cerevisiae)
catalog :
N0379
citations: 89
Reference
Shima T, Morikawa M, Kaneshiro J, Kambara T, Kamimura S, Yagi T, et al. Kinesin-binding-triggered conformation switching of microtubules contributes to polarized transport. J Cell Biol. 2018;217:4164-4183 pubmed publisher
Barlow S, Metcalfe J, Righton D, Berenbrink M. Life on the edge: O2 binding in Atlantic cod red blood cells near their southern distribution limit is not sensitive to temperature or haemoglobin genotype. J Exp Biol. 2017;220:414-424 pubmed publisher
Chinen T, Liu P, Shioda S, Pagel J, Cerikan B, Lin T, et al. The γ-tubulin-specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle. Nat Commun. 2015;6:8722 pubmed publisher
Chuang C, Liu C, Lu T, Hu M. Suppression of alpha-tocopherol ether-linked acetic acid in VEGF-induced angiogenesis and the possible mechanisms in human umbilical vein endothelial cells. Toxicol Appl Pharmacol. 2014;281:310-6 pubmed publisher
Taverniti V, Séraphin B. Elimination of cap structures generated by mRNA decay involves the new scavenger mRNA decapping enzyme Aph1/FHIT together with DcpS. Nucleic Acids Res. 2015;43:482-92 pubmed publisher
Auger C, Appanna V. A novel ATP-generating machinery to counter nitrosative stress is mediated by substrate-level phosphorylation. Biochim Biophys Acta. 2015;1850:43-50 pubmed publisher
Feng Y, Gross S, Wolf N, Butenschön V, Qiu Y, Devraj K, et al. Nucleoside diphosphate kinase B regulates angiogenesis through modulation of vascular endothelial growth factor receptor type 2 and endothelial adherens junction proteins. Arterioscler Thromb Vasc Biol. 2014;34:2292-300 pubmed publisher
Kim Y, Lee J, Lee Y, Jia J, Paek S, Kim H, et al. Nucleoside diphosphate kinase and flagellin from Pseudomonas aeruginosa induce interleukin 1 expression via the Akt/NF-κB signaling pathways. Infect Immun. 2014;82:3252-60 pubmed publisher
Pereira C, Reigada C, Sayé M, Digirolamo F, Miranda M. Cytosolic Trypanosoma cruzi nucleoside diphosphate kinase generates large granules that depend on its quaternary structure. Exp Parasitol. 2014;142:43-50 pubmed publisher
Kunzelmann K, Mehta A. CFTR: a hub for kinases and crosstalk of cAMP and Ca2+. FEBS J. 2013;280:4417-29 pubmed publisher
Chen S, Su L, Qiu J, Xiao N, Lin J, Tan J, et al. Mechanistic studies for the role of cellular nucleic-acid-binding protein (CNBP) in regulation of c-myc transcription. Biochim Biophys Acta. 2013;1830:4769-77 pubmed publisher
Qu L, Liang L, Su J, Yang Z. Inhibitory effect of upregulated DR-nm23 expression on invasion and metastasis in colorectal cancer. Eur J Cancer Prev. 2013;22:512-22 pubmed publisher
Gong L, Wu Z, Guo L, Li L, Zhao R, Zhu D, et al. Metastasis suppressor Nm23-H1 inhibits STAT3 signaling via a negative feedback mechanism. Biochem Biophys Res Commun. 2013;434:541-6 pubmed publisher
Markowska J, Bar J, Madry R, Słomska I, Mardas M, Grabowski J. The expression of BRCA1, P53, KAI1, and Nm23 in ovaries of BRCA1 mutation carriers after prophylactic adnexectomy. Arch Gynecol Obstet. 2013;288:839-44 pubmed publisher
Georgescauld F, Moynié L, Habersetzer J, Cervoni L, Mocan I, Borza T, et al. Intersubunit ionic interactions stabilize the nucleoside diphosphate kinase of Mycobacterium tuberculosis. PLoS ONE. 2013;8:e57867 pubmed publisher
Carotenuto M, Pedone E, Diana D, De Antonellis P, Dzeroski S, Marino N, et al. Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction. Sci Rep. 2013;3:1351 pubmed publisher
Sekiguchi T, Ito R, Hayakawa H, Sekiguchi M. Elimination and utilization of oxidized guanine nucleotides in the synthesis of RNA and its precursors. J Biol Chem. 2013;288:8128-35 pubmed publisher
Lahiri D, Maloney B, Rogers J, Ge Y. PuF, an antimetastatic and developmental signaling protein, interacts with the Alzheimer's amyloid-? precursor protein via a tissue-specific proximal regulatory element (PRE). BMC Genomics. 2013;14:68 pubmed publisher
Lin S, Chou H, Chen Y, Chan H. Redox-proteomic analysis of doxorubicin-induced altered thiol activity in cardiomyocytes. Mol Biosyst. 2013;9:447-56 pubmed publisher
Hoffmann F, Strodel B. Protein structure prediction using global optimization by basin-hopping with NMR shift restraints. J Chem Phys. 2013;138:025102 pubmed publisher
Pagaev R, Kakuev D, Pozdeev V, Kutuzov M, Rakitina T, Lipkin V. The light chain of the dynein complex DYNLRB1 interacts with NDP-kinase a from bovine retina. Dokl Biochem Biophys. 2012;447:286-8 pubmed publisher
Schaaper R, Mathews C. Mutational consequences of dNTP pool imbalances in E. coli. DNA Repair (Amst). 2013;12:73-9 pubmed publisher
Lee S, Park H, Cho N, Choi Y, Rha S, Park S, et al. Identifying genes related to radiation resistance in oral squamous cell carcinoma cell lines. Int J Oral Maxillofac Surg. 2013;42:169-76 pubmed publisher
Liu J, Yang Y, Fu X, Yu Y, Gu L. [Significance of TIMP-1 and nm-23 expressions in HER-2-positive breast cancer]. Zhonghua Zhong Liu Za Zhi. 2012;34:600-4 pubmed publisher
Schlattner U, Tokarska Schlattner M, Ramirez S, Tyurina Y, Amoscato A, Mohammadyani D, et al. Dual function of mitochondrial Nm23-H4 protein in phosphotransfer and intermembrane lipid transfer: a cardiolipin-dependent switch. J Biol Chem. 2013;288:111-21 pubmed publisher
Zhao R, Gong L, Li L, Guo L, Zhu D, Wu Z, et al. nm23-H1 is a negative regulator of TGF-β1-dependent induction of epithelial-mesenchymal transition. Exp Cell Res. 2013;319:740-9 pubmed publisher
Sinha D, Atray I, Bentur J, Nair S. Expression of Orseolia oryzae nucleoside diphosphate kinase (OoNDPK) is enhanced in rice gall midge feeding on susceptible rice hosts and its over-expression leads to salt tolerance in Escherichia coli. Insect Mol Biol. 2012;21:593-603 pubmed publisher
Prabhu V, Siddikuzzaman -, Grace V, Guruvayoorappan C. Targeting tumor metastasis by regulating Nm23 gene expression. Asian Pac J Cancer Prev. 2012;13:3539-48 pubmed
Lim J, Lu J, He B. Diva/BclB regulates differentiation by inhibiting NDPKB/Nm23H2-mediated neuronal differentiation in PC-12 cells. BMC Neurosci. 2012;13:123 pubmed publisher
Prabu G, Thirugnanasambantham K, Mandal A. Structural and docking studies of a nucleoside diphosphate kinase 1 (CsNDPK1) from tea [Camellia sinensis (L.) O. Kuntze]. Appl Biochem Biotechnol. 2012;168:1907-16 pubmed publisher
Owlanj H, Jie Yang H, Wei Feng Z. Nucleoside diphosphate kinase Nm23-M1 involves in oligodendroglial versus neuronal cell fate decision in vitro. Differentiation. 2012;84:281-93 pubmed publisher
Marioni G, Ottaviano G, Lionello M, Lora L, Lovato A, Staffieri C, et al. Nm23-H1 nuclear expression is associated with a more favourable prognosis in laryngeal carcinoma: univariate and multivariate analysis. Histopathology. 2012;61:1057-64 pubmed publisher
François Moutal L, Maniti O, Marcillat O, Granjon T. New insights into lipid-Nucleoside Diphosphate Kinase-D interaction mechanism: protein structural changes and membrane reorganisation. Biochim Biophys Acta. 2013;1828:906-15 pubmed publisher
Li A, Zhou X, Wang Z, Song Y, Gao P, Miao Y, et al. Associations of non-metastatic cells 1 gene polymorphisms with lymph node metastasis risk of gastric cancer in Northern Chinese population. Tumour Biol. 2012;33:2159-66 pubmed publisher
Wang C, Ma N, Lin Y, Wu C, Hsiao M, Lu F, et al. A shRNA functional screen reveals Nme6 and Nme7 are crucial for embryonic stem cell renewal. Stem Cells. 2012;30:2199-211 pubmed publisher
Lipskaya T, Voinova V. Activity of nucleoside diphosphate kinase ? (NDPK ?) capable of binding to outer mitochondrial membrane accounts for less than 10% of total NDPK activity present in cytoplasm of liver cells. Biochemistry (Mosc). 2012;77:593-602 pubmed publisher
Wang X, Sun R, Wu M, Li T, Zhang Y, Chen L. Differential protein expression in EC304 gastric cancer cells induced by alphastatin. Asian Pac J Cancer Prev. 2012;13:1667-74 pubmed
Leopoldino A, Squarize C, Garcia C, Almeida L, Pestana C, Sobral L, et al. SET protein accumulates in HNSCC and contributes to cell survival: antioxidant defense, Akt phosphorylation and AVOs acidification. Oral Oncol. 2012;48:1106-13 pubmed publisher
Tanaka M, Kuriyama S, Aiba N. Nm23-H1 regulates contact inhibition of locomotion, which is affected by ephrin-B1. J Cell Sci. 2012;125:4343-53 pubmed publisher
Jarrett S, Novak M, Harris N, Merlino G, Slominski A, Kaetzel D. NM23 deficiency promotes metastasis in a UV radiation-induced mouse model of human melanoma. Clin Exp Metastasis. 2013;30:25-36 pubmed publisher
Bauer H, Schindler S, Charron Y, Willert J, Kusecek B, Herrmann B. The nucleoside diphosphate kinase gene Nme3 acts as quantitative trait locus promoting non-Mendelian inheritance. PLoS Genet. 2012;8:e1002567 pubmed publisher
Burkard T, Planyavsky M, Kaupe I, Breitwieser F, Burckstummer T, Bennett K, et al. Initial characterization of the human central proteome. BMC Syst Biol. 2011;5:17 pubmed publisher
Wieland T, Hippe H, Ludwig K, Zhou X, Korth M, Klumpp S. Reversible histidine phosphorylation in mammalian cells: a teeter-totter formed by nucleoside diphosphate kinase and protein histidine phosphatase 1. Methods Enzymol. 2010;471:379-402 pubmed publisher
Choudhary C, Kumar C, Gnad F, Nielsen M, Rehman M, Walther T, et al. Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science. 2009;325:834-40 pubmed publisher
Jeudy S, Lartigue A, Claverie J, Abergel C. Dissecting the unique nucleotide specificity of mimivirus nucleoside diphosphate kinase. J Virol. 2009;83:7142-50 pubmed publisher
Gauci S, Helbig A, Slijper M, Krijgsveld J, Heck A, Mohammed S. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. Anal Chem. 2009;81:4493-501 pubmed publisher
Meierhofer D, Wang X, Huang L, Kaiser P. Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry. J Proteome Res. 2008;7:4566-76 pubmed publisher
Garzia L, D Angelo A, Amoresano A, Knauer S, Cirulli C, Campanella C, et al. Phosphorylation of nm23-H1 by CKI induces its complex formation with h-prune and promotes cell motility. Oncogene. 2008;27:1853-64 pubmed
Gregory S, Barlow K, McLay K, Kaul R, Swarbreck D, Dunham A, et al. The DNA sequence and biological annotation of human chromosome 1. Nature. 2006;441:315-21 pubmed
Muzny D, Scherer S, Kaul R, Wang J, Yu J, Sudbrak R, et al. The DNA sequence, annotation and analysis of human chromosome 3. Nature. 2006;440:1194-8 pubmed
Zody M, Garber M, Adams D, Sharpe T, Harrow J, Lupski J, et al. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. Nature. 2006;440:1045-9 pubmed
Scherer S, Muzny D, Buhay C, Chen R, Cree A, Ding Y, et al. The finished DNA sequence of human chromosome 12. Nature. 2006;440:346-51 pubmed
Valentijn L, Koster J, Versteeg R. Read-through transcript from NM23-H1 into the neighboring NM23-H2 gene encodes a novel protein, NM23-LV. Genomics. 2006;87:483-9 pubmed
Martin J, Han C, Gordon L, Terry A, Prabhakar S, She X, et al. The sequence and analysis of duplication-rich human chromosome 16. Nature. 2004;432:988-94 pubmed
Gerhard D, Wagner L, Feingold E, Shenmen C, Grouse L, Schuler G, et al. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004;14:2121-7 pubmed
Iwashita S, Fujii M, Mukai H, Ono Y, Miyamoto M. Lbc proto-oncogene product binds to and could be negatively regulated by metastasis suppressor nm23-H2. Biochem Biophys Res Commun. 2004;320:1063-8 pubmed
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, et al. Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet. 2004;36:40-5 pubmed
KIRKLAND R, Turner J. Nucleoside diphosphokinase of pea seeds. Biochem J. 1959;72:716-20 pubmed
Ratliff R, Weaver R, Lardy H, Kuby S. NUCLEOSIDE TRIPHOSPHATE-NUCLEOSIDE DIPHOSPHATE TRANSPHOSPHORYLASE (NUCLEOSIDE DIPHOSPHOKINASE). I. ISOLATION OF THE CRYSTALLINE ENZYME FROM BREWERS' YEAST. J Biol Chem. 1964;239:301-9 pubmed
AYENGAR P, Gibson D, Sanadi D. Transphosphorylations between nucleoside phosphates. Biochim Biophys Acta. 1956;21:86-91 pubmed
Berg P, Joklik W. Enzymatic phosphorylation of nucleoside diphosphates. J Biol Chem. 1954;210:657-72 pubmed
Krebs H, Hems R. Some reactions of adenosine and inosine phosphates in animal tissues. Biochim Biophys Acta. 1953;12:172-80 pubmed
Chen Y, Gallois Montbrun S, Schneider B, Veron M, Morera S, Deville Bonne D, et al. Nucleotide binding to nucleoside diphosphate kinases: X-ray structure of human NDPK-A in complex with ADP and comparison to protein kinases. J Mol Biol. 2003;332:915-26 pubmed
Fan Z, Beresford P, Oh D, Zhang D, Lieberman J. Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor. Cell. 2003;112:659-72 pubmed
Ni X, Gu S, Dai J, Cheng H, Guo L, Li L, et al. Isolation and characterization of a novel human NM23-H1B gene, a different transcript of NM23-H1. J Hum Genet. 2003;48:96-100 pubmed
Fournier H, Dupe Manet S, Bouvard D, Lacombe M, Marie C, Block M, et al. Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement. J Biol Chem. 2002;277:20895-902 pubmed
Min K, Song H, Chang C, Kim S, Lee K, Suh S. Crystal structure of human nucleoside diphosphate kinase A, a metastasis suppressor. Proteins. 2002;46:340-2 pubmed
Venter J, Adams M, Myers E, Li P, Mural R, Sutton G, et al. The sequence of the human genome. Science. 2001;291:1304-51 pubmed
Daniels R, Peden J, Lloyd C, Horsley S, Clark K, Tufarelli C, et al. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. Hum Mol Genet. 2001;10:339-52 pubmed
Milon L, Meyer P, Chiadmi M, Munier A, Johansson M, Karlsson A, et al. The human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinase. J Biol Chem. 2000;275:14264-72 pubmed
Manda R, Kohno T, Matsuno Y, Takenoshita S, Kuwano H, Yokota J. Identification of genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display. Genomics. 1999;61:5-14 pubmed
Mehus J, Deloukas P, Lambeth D. NME6: a new member of the nm23/nucleoside diphosphate kinase gene family located on human chromosome 3p21.3. Hum Genet. 1999;104:454-9 pubmed
Milon L, Rousseau Merck M, Munier A, Erent M, Lascu I, Capeau J, et al. nm23-H4, a new member of the family of human nm23/nucleoside diphosphate kinase genes localised on chromosome 16p13. Hum Genet. 1997;99:550-7 pubmed
Macdonald N, Freije J, Stracke M, Manrow R, Steeg P. Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells. J Biol Chem. 1996;271:25107-16 pubmed
Morera S, Lacombe M, Xu Y, Lebras G, Janin J. X-ray structure of human nucleoside diphosphate kinase B complexed with GDP at 2 A resolution. Structure. 1995;3:1307-14 pubmed
Postel E, Berberich S, Flint S, Ferrone C. Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis. Science. 1993;261:478-80 pubmed
Dooley S, Seib T, Engel M, Theisinger B, Janz H, Piontek K, et al. Isolation and characterization of the human genomic locus coding for the putative metastasis control gene nm23-H1. Hum Genet. 1994;93:63-6 pubmed
Chang C, Zhu X, Thoraval D, Ungar D, Rawwas J, Hora N, et al. Nm23-H1 mutation in neuroblastoma. Nature. 1994;370:335-6 pubmed
Wang L, Patel U, Ghosh L, Chen H, Banerjee S. Mutation in the nm23 gene is associated with metastasis in colorectal cancer. Cancer Res. 1993;53:717-20 pubmed
Webb P, Perisic O, Mendola C, Backer J, Williams R. The crystal structure of a human nucleoside diphosphate kinase, NM23-H2. J Mol Biol. 1995;251:574-87 pubmed
Venturelli D, Martinez R, Melotti P, Casella I, Peschle C, Cucco C, et al. Overexpression of DR-nm23, a protein encoded by a member of the nm23 gene family, inhibits granulocyte differentiation and induces apoptosis in 32Dc13 myeloid cells. Proc Natl Acad Sci U S A. 1995;92:7435-9 pubmed
Seifert M, Seib T, Engel M, Dooley S, Welter C. Characterization of the human nm23-H2 promoter region and localization of the microsatellite D17S396. Biochem Biophys Res Commun. 1995;215:910-4 pubmed
Roy R, Nasrin N, Ahmad M, Gupta N. Protein synthesis in rabbit reticulocytes: requirements for Met-tRNAf . 40S preinitiation complex formation with AUG-codon and physiological mRNAs. Biochem Biophys Res Commun. 1984;122:1418-25 pubmed
Nakamura H, Sugino Y. Metabolism of deoxyribonucleotides. 3. Purification and some properties of nucleoside diphosphokinase of calf thymus. J Biol Chem. 1966;241:4917-22 pubmed
Rosengard A, Krutzsch H, Shearn A, Biggs J, Barker E, Margulies I, et al. Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development. Nature. 1989;342:177-80 pubmed
Hailat N, Keim D, Melhem R, Zhu X, Eckerskorn C, Brodeur G, et al. High levels of p19/nm23 protein in neuroblastoma are associated with advanced stage disease and with N-myc gene amplification. J Clin Invest. 1991;88:341-5 pubmed
Stahl J, Leone A, Rosengard A, Porter L, King C, Steeg P. Identification of a second human nm23 gene, nm23-H2. Cancer Res. 1991;51:445-9 pubmed
Gilles A, Presecan E, Vonica A, Lascu I. Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme. J Biol Chem. 1991;266:8784-9 pubmed
Hemmerich S, Sijpkens D, Pecht I. A novel cell-permeable cromoglycate derivative inhibits type I Fc epsilon receptor mediated Ca2+ influx and mediator secretion in rat mucosal mast cells. Biochemistry. 1991;30:1523-32 pubmed
product information
Catalog Number :
N0379
Product Name :
Nucleoside 5′-Diphosphate Kinase from baker's yeast (S. cerevisiae)
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
lyophilized powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA