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product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Methyl 4-hydroxybenzoate
catalog :
M8911
citations: 78
Reference
Sadeghi Goughari M, Jeon S, Kwon H. Enhancing Thermal Effect of Focused Ultrasound Therapy Using Gold Nanoparticles. IEEE Trans Nanobioscience. 2019;18:661-668 pubmed publisher
Cortéjade A, Kiss A, Cren C, Vulliet E, Buleté A. Development of an analytical method for the targeted screening and multi-residue quantification of environmental contaminants in urine by liquid chromatography coupled to high resolution mass spectrometry for evaluation of human exposures. Talanta. 2016;146:694-706 pubmed publisher
Cacho J, Campillo N, Viñas P, Hernández Córdoba M. Improved sensitivity gas chromatography-mass spectrometry determination of parabens in waters using ionic liquids. Talanta. 2016;146:568-74 pubmed publisher
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Han C, Xia B, Chen X, Shen J, Miao Q, Shen Y. Determination of four paraben-type preservatives and three benzophenone-type ultraviolet light filters in seafoods by LC-QqLIT-MS/MS. Food Chem. 2016;194:1199-207 pubmed publisher
Bennis Y, Savry A, Correard F, Montana M, Sauzet C, Gauthier Villano L, et al. Stability of a highly concentrated solution of epirubicin for conventional transcatheter arterial chemoembolization. Int J Pharm. 2015;495:956-62 pubmed publisher
Li W, Gao L, Shi Y, Wang Y, Liu J, Cai Y. Spatial distribution, temporal variation and risks of parabens and their chlorinated derivatives in urban surface water in Beijing, China. Sci Total Environ. 2016;539:262-270 pubmed publisher
Wróbel A, Gregoraszczuk E. Action of methyl-, propyl- and butylparaben on GPR30 gene and protein expression, cAMP levels and activation of ERK1/2 and PI3K/Akt signaling pathways in MCF-7 breast cancer cells and MCF-10A non-transformed breast epithelial cells. Toxicol Lett. 2015;238:110-6 pubmed publisher
Bai H, Post S, Kang P, Tatar M. Drosophila Longevity Assurance Conferred by Reduced Insulin Receptor Substrate Chico Partially Requires d4eBP. PLoS ONE. 2015;10:e0134415 pubmed publisher
Bou Sleiman M, Osman D, Massouras A, Hoffmann A, Lemaitre B, Deplancke B. Genetic, molecular and physiological basis of variation in Drosophila gut immunocompetence. Nat Commun. 2015;6:7829 pubmed publisher
Hatanaka T, Yoshida S, Kadhum W, Todo H, Sugibayashi K. In Silico Estimation of Skin Concentration Following the Dermal Exposure to Chemicals. Pharm Res. 2015;32:3965-74 pubmed publisher
Li W, Shi Y, Gao L, Liu J, Cai Y. Occurrence and human exposure of parabens and their chlorinated derivatives in swimming pools. Environ Sci Pollut Res Int. 2015;22:17987-97 pubmed publisher
Sola M, Dahners L, Weinhold P, Svetkey van der Horst A, Kallianos S, Flood D. The viability of chondrocytes after an in vivo injection of local anaesthetic and/or corticosteroid: a laboratory study using a rat model. Bone Joint J. 2015;97-B:933-8 pubmed publisher
Rodas M, Portugal L, Avivar J, Estela J, Cerdà V. Parabens determination in cosmetic and personal care products exploiting a multi-syringe chromatographic (MSC) system and chemiluminescent detection. Talanta. 2015;143:254-262 pubmed publisher
Kosova M, Hradkova I, Mátlová V, Kadlec D, Smidrkal J, Filip V. Antimicrobial effect of 4-hydroxybenzoic acid ester with glycerol. J Clin Pharm Ther. 2015;40:436-40 pubmed publisher
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Myridakis A, Balaska E, Gkaitatzi C, Kouvarakis A, Stephanou E. Determination and separation of bisphenol A, phthalate metabolites and structural isomers of parabens in human urine with conventional high-pressure liquid chromatography combined with electrospray ionisation tandem mass spectrometry. Anal Bioanal Chem. 2015;407:2509-18 pubmed publisher
Figueiredo K, Medeiros S, Neves J, da Silva J, da Rocha Tomé A, Carvalho A, et al. In vivo evaluation of anticonvulsant and antioxidant effects of phenobarbital microemulsion for transdermal administration in pilocarpine seizure rat model. Pharmacol Biochem Behav. 2015;131:6-12 pubmed publisher
Kapalavavi B, Marple R, Gamsky C, Yang Y. Studies on the stability of preservatives under subcritical water conditions. Int J Cosmet Sci. 2015;37:306-11 pubmed publisher
Manservisi F, Gopalakrishnan K, Tibaldi E, Hysi A, Iezzi M, Lambertini L, et al. Effect of maternal exposure to endocrine disrupting chemicals on reproduction and mammary gland development in female Sprague-Dawley rats. Reprod Toxicol. 2015;54:110-9 pubmed publisher
Kim T, Seok S, Kim K, Shin B, Lee J, Choi Y, et al. LC-APCI-MS/MS Quantification and Topical Bioavailability of Chloroacetamide in Rats. J Chromatogr Sci. 2015;53:1100-6 pubmed publisher
Lauterbach A, Müller Goymann C. Comparison of rheological properties, follicular penetration, drug release, and permeation behavior of a novel topical drug delivery system and a conventional cream. Eur J Pharm Biopharm. 2014;88:614-24 pubmed
Connell J, Sugihara Y, Torok S, Dome B, Tovari J, Fehniger T, et al. Localization of sunitinib in in vivo animal and in vitro experimental models by MALDI mass spectrometry imaging. Anal Bioanal Chem. 2015;407:2245-53 pubmed publisher
Hou Y, Zhao J, Li X, Cui J, Ding J, Wang Y, et al. Smart Soup, a traditional Chinese medicine formula, ameliorates amyloid pathology and related cognitive deficits. PLoS ONE. 2014;9:e111215 pubmed publisher
Carlucci G, Selvaggi F, Sulpizio S, Bassi C, Carlucci M, Cotellese R, et al. Combined derivatization and high-performance liquid chromatography with fluorescence and ultraviolet detection for simultaneous analysis of octreotide and gabexate mesylate metabolite in human pancreatic juice samples. Biomed Chromatogr. 2015;29:911-7 pubmed publisher
Fadel M, Tawfik A. New topical photodynamic therapy for treatment of hidradenitis suppurativa using methylene blue niosomal gel: a single-blind, randomized, comparative study. Clin Exp Dermatol. 2015;40:116-22 pubmed publisher
Aggarwal P, Lawson J, Tolley H, Lee M. High efficiency polyethylene glycol diacrylate monoliths for reversed-phase capillary liquid chromatography of small molecules. J Chromatogr A. 2014;1364:96-106 pubmed publisher
Kolšek K, Gobec M, Mlinarič Raščan I, Sollner Dolenc M. Screening of bisphenol A, triclosan and paraben analogues as modulators of the glucocorticoid and androgen receptor activities. Toxicol In Vitro. 2015;29:8-15 pubmed publisher
Shankar G, Alt C. Prophylactic treatment with a novel bioadhesive gel formulation containing aciclovir and tenofovir protects from HSV-2 infection. J Antimicrob Chemother. 2014;69:3282-93 pubmed publisher
Wróbel A, Gregoraszczuk E. Actions of methyl-, propyl- and butylparaben on estrogen receptor-? and -? and the progesterone receptor in MCF-7 cancer cells and non-cancerous MCF-10A cells. Toxicol Lett. 2014;230:375-81 pubmed publisher
Sonawane R, Harde H, Katariya M, Agrawal S, Jain S. Solid lipid nanoparticles-loaded topical gel containing combination drugs: an approach to offset psoriasis. Expert Opin Drug Deliv. 2014;11:1833-47 pubmed publisher
Fekete S, Fekete J, Guillarme D. Estimation of the effects of longitudinal temperature gradients caused by frictional heating on the solute retention using fully porous and superficially porous sub-2μm materials. J Chromatogr A. 2014;1359:124-30 pubmed publisher
Asakawa Y, Yamamoto E, Asakawa N. Selective retention of basic compounds by metal aquo-ion affinity chromatography. J Sep Sci. 2014;37:2641-51 pubmed publisher
Kaylor A, Dwivedi P, Pittman J, Monge M, Cheng G, Li S, et al. Plasma-spray ionization (PLASI): a multimodal atmospheric pressure ion source for liquid stream analysis. J Am Soc Mass Spectrom. 2014;25:1788-93 pubmed publisher
Celano R, Piccinelli A, Campone L, Rastrelli L. Ultra-preconcentration and determination of selected pharmaceutical and personal care products in different water matrices by solid-phase extraction combined with dispersive liquid-liquid microextraction prior to ultra high pressure liquid chromatogr. J Chromatogr A. 2014;1355:26-35 pubmed publisher
Rodriguez A, Kleinbeck K, Mizenina O, Kizima L, Levendosky K, Jean Pierre N, et al. In vitro and in vivo evaluation of two carrageenan-based formulations to prevent HPV acquisition. Antiviral Res. 2014;108:88-93 pubmed publisher
Gorga M, Insa S, Petrovic M, Barcelo D. Analysis of endocrine disrupters and related compounds in sediments and sewage sludge using on-line turbulent flow chromatography-liquid chromatography-tandem mass spectrometry. J Chromatogr A. 2014;1352:29-37 pubmed publisher
Canavesi R, Aprile S, Varese E, Grosa G. Development and validation of a stability-indicating LC-UV method for the determination of pantethine and its degradation product based on a forced degradation study. J Pharm Biomed Anal. 2014;97:141-50 pubmed publisher
Li Y, Piao D, Zhang H, Kim T, Lee S, Chang H, et al. Quality evaluation of Carthami Flos by HPLC-UV. Arch Pharm Res. 2015;38:776-84 pubmed publisher
Kalat S, Khamesipour A, Bavarsad N, Fallah M, Khashayarmanesh Z, Feizi E, et al. Use of topical liposomes containing meglumine antimoniate (Glucantime) for the treatment of L. major lesion in BALB/c mice. Exp Parasitol. 2014;143:5-10 pubmed publisher
Tustin A, Kim S, Chomsky A, Hubbard G, Sheng J. Antibacterial properties of 2% lidocaine and reduced rate of endophthalmitis after intravitreal injection. Retina. 2014;34:935-42 pubmed publisher
Orton F, Ermler S, Kugathas S, Rosivatz E, Scholze M, Kortenkamp A. Mixture effects at very low doses with combinations of anti-androgenic pesticides, antioxidants, industrial pollutant and chemicals used in personal care products. Toxicol Appl Pharmacol. 2014;278:201-8 pubmed publisher
San Segundo L, Martini F, Pablos M. Gene expression responses for detecting sublethal effects of xenobiotics and whole effluents on a Xenopus laevis embryo assay. Environ Toxicol Chem. 2013;32:2018-25 pubmed publisher
Naik K, Nandibewoor S. Spectral characterization of the binding and conformational changes of bovine serum albumin upon interaction with an anti-fungal drug, methylparaben. Spectrochim Acta A Mol Biomol Spectrosc. 2013;105:418-23 pubmed publisher
Baranowska I, Wojciechowska I, Solarz N, Krutysza E. Determination of preservatives in cosmetics, cleaning agents and pharmaceuticals using fast liquid chromatography. J Chromatogr Sci. 2014;52:88-94 pubmed publisher
Dolan L, Wheeler J, Burdock G. Safety studies conducted on a sanitizing agent containing benzalkonium chloride. J Food Sci. 2013;78:T119-27 pubmed publisher
Khimani M, Ganguly R, Aswal V, Nath S, Bahadur P. Solubilization of parabens in aqueous Pluronic solutions: investigating the micellar growth and interaction as a function of paraben composition. J Phys Chem B. 2012;116:14943-50 pubmed publisher
Kessler R. Superbug hideout: finding MRSA in U.S.wastewater treatment plants. Environ Health Perspect. 2012;120:A437 pubmed publisher
Kopalli S, Noh S, Koppula S, Suh Y. Methylparaben protects 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells and improved behavioral impairments in mouse model of Parkinson's disease. Neurotoxicology. 2013;34:25-32 pubmed publisher
Silva G, Bottoli C, Groppo F, Volpato M, Ranali J, Ramacciato J, et al. Methylparaben concentration in commercial Brazilian local anesthetics solutions. J Appl Oral Sci. 2012;20:444-8 pubmed
Oluremi B, Bamiro O, Idowu A, Oduneye O. Effect of compression pressure, preservative, and storage with potassium chloride on the microbiological quality of tablets formulated with Terminalia randii Gum (Combretaceae). Pak J Pharm Sci. 2012;25:773-6 pubmed
Oliveira G, Hadgraft J, Lane M. The role of vehicle interactions on permeation of an active through model membranes and human skin. Int J Cosmet Sci. 2012;34:536-45 pubmed publisher
Dagher Z, Borgie M, Magdalou J, Chahine R, Greige Gerges H. p-Hydroxybenzoate esters metabolism in MCF7 breast cancer cells. Food Chem Toxicol. 2012;50:4109-14 pubmed publisher
Yu K, Li B, Zhang T. Direct rapid analysis of multiple PPCPs in municipal wastewater using ultrahigh performance liquid chromatography-tandem mass spectrometry without SPE pre-concentration. Anal Chim Acta. 2012;738:59-68 pubmed publisher
Santos I, Ramos C, Ramos J, Oliveira R, Cunha I. Efficient association between PGF2α and methyl 4-hydroxybenzoate sex pheromone prior to electroejaculation in dogs. Reprod Domest Anim. 2013;48:160-4 pubmed publisher
Smith K, Braun J, Williams P, Ehrlich S, Correia K, Calafat A, et al. Predictors and variability of urinary paraben concentrations in men and women, including before and during pregnancy. Environ Health Perspect. 2012;120:1538-43 pubmed publisher
Al Za abi M, Ali B, Al Toubi M. HPLC-fluorescence method for measurement of the uremic toxin indoxyl sulfate in plasma. J Chromatogr Sci. 2013;51:40-3 pubmed publisher
Wattanasatcha A, Rengpipat S, Wanichwecharungruang S. Thymol nanospheres as an effective anti-bacterial agent. Int J Pharm. 2012;434:360-5 pubmed publisher
Oliveira G, Hadgraft J, Lane M. The influence of volatile solvents on transport across model membranes and human skin. Int J Pharm. 2012;435:38-49 pubmed publisher
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Hewala I, El Fatatry H, Emam E, Mabrouk M. Development and application of a validated stability-indicating high-performance liquid chromatographic method using photodiode array detection for simultaneous determination of granisetron, methylparaben, propylparaben, sodium benzoate, and their ma. J AOAC Int. 2011;94:1447-60 pubmed
Miceli M, Bernardo S, Ku T, Walraven C, Lee S. In vitro analyses of the effects of heparin and parabens on Candida albicans biofilms and planktonic cells. Antimicrob Agents Chemother. 2012;56:148-53 pubmed publisher
Oliveira G, Beezer A, Hadgraft J, Lane M. Alcohol enhanced permeation in model membranes. Part II. Thermodynamic analysis of membrane partitioning. Int J Pharm. 2011;420:216-22 pubmed publisher
Tappeiner C, Garweg J. Retinal vascular occlusion after vitrectomy with retrobulbar anesthesia-observational case series and survey of literature. Graefes Arch Clin Exp Ophthalmol. 2011;249:1831-5 pubmed publisher
Kulik A, Szczotkowska A, Białecka W, Podolska M, Kwiatkowska Puchniarz B, Mazurek A. Determination of active substances in binary mixture antiparasitic veterinary formulations by HPLC. Acta Pol Pharm. 2011;68:467-72 pubmed
Kannathasan K, Senthilkumar A, Venkatesalu V. Mosquito larvicidal activity of methyl-p-hydroxybenzoate isolated from the leaves of Vitex trifolia Linn. Acta Trop. 2011;120:115-8 pubmed publisher
Makaji E, Raha S, Wade M, Holloway A. Effect of environmental contaminants on Beta cell function. Int J Toxicol. 2011;30:410-8 pubmed publisher
Kruhlak N, Choi S, Contrera J, Weaver J, Willard J, Hastings K, et al. Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicol Mech Methods. 2008;18:217-27 pubmed publisher
McNamara P, Syverson R, Milligan Myhre K, Frolova O, Schroeder S, Kidder J, et al. Surfactants, aromatic and isoprenoid compounds, and fatty acid biosynthesis inhibitors suppress Staphylococcus aureus production of toxic shock syndrome toxin 1. Antimicrob Agents Chemother. 2009;53:1898-906 pubmed publisher
Lv P, Xiao Z, Fang R, Li H, Zhu H, Liu C. Synthesis, characterization and structure-activity relationship analysis of novel depsides as potential antibacterials. Eur J Med Chem. 2009;44:1779-87 pubmed publisher
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Lill M, Winiger F, Vedani A, Ernst B. Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. J Med Chem. 2005;48:5666-74 pubmed
Soni M, Taylor S, Greenberg N, Burdock G. Evaluation of the health aspects of methyl paraben: a review of the published literature. Food Chem Toxicol. 2002;40:1335-73 pubmed
product information
Catalog Number :
M8911
Product Name :
Methyl 4-hydroxybenzoate
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
analytical standard
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA