product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-Myosin (Skeletal, Slow) antibody produced in mouse
catalog :
M8421
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
NOQ7.5.4D
reactivity :
human, mouse, rat, dogs, chicken, bovine, rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, radioimmunoassay, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 213
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:500; loading ...; fig 2h
Bella P, Farini A, Banfi S, Parolini D, Tonna N, Meregalli M, et al. Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy. EMBO Mol Med. 2020;12:e11019 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:1000; loading ...; fig 1b
Nofi C, Bogatyryov Y, Dedkov E. Preservation of Functional Microvascular Bed Is Vital for Long-Term Survival of Cardiac Myocytes Within Large Transmural Post-Myocardial Infarction Scar. J Histochem Cytochem. 2017;:22155417741640 pubmed publisher
  • western blot; mouse; loading ...; fig 7a
Gopinath S. Inhibition of Stat3 signaling ameliorates atrophy of the soleus muscles in mice lacking the vitamin D receptor. Skelet Muscle. 2017;7:2 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:100; loading ...; fig 2a
Hu N, Chang H, Du B, Zhang Q, Arfat Y, Dang K, et al. Tetramethylpyrazine ameliorated disuse-induced gastrocnemius muscle atrophy in hindlimb unloading rats through suppression of Ca2+/ROS-mediated apoptosis. Appl Physiol Nutr Metab. 2017;42:117-127 pubmed publisher
  • immunohistochemistry; mouse; 2 ug/ml; loading ...; fig 2a
  • immunohistochemistry; rat; 2 ug/ml; loading ...; fig 2a
Sawano S, Komiya Y, Ichitsubo R, Ohkawa Y, Nakamura M, Tatsumi R, et al. A One-Step Immunostaining Method to Visualize Rodent Muscle Fiber Type within a Single Specimen. PLoS ONE. 2016;11:e0166080 pubmed publisher
  • immunohistochemistry; rat; 1:10,000; fig 5a
Pumberger M, Qazi T, Ehrentraut M, Textor M, Kueper J, Stoltenburg Didinger G, et al. Synthetic niche to modulate regenerative potential of MSCs and enhance skeletal muscle regeneration. Biomaterials. 2016;99:95-108 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:2000; loading ...; fig 3a, b
Jensen L, Jørgensen L, Bech R, Frandsen U, Schrøder H. Skeletal Muscle Remodelling as a Function of Disease Progression in Amyotrophic Lateral Sclerosis. Biomed Res Int. 2016;2016:5930621 pubmed publisher
  • immunohistochemistry; human; 1:1000; loading ...; tbl 2
Nyberg M, Fiorenza M, Lund A, Christensen M, Rømer T, Piil P, et al. Adaptations to Speed Endurance Training in Highly Trained Soccer Players. Med Sci Sports Exerc. 2016;48:1355-64 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:600; fig 4
Watanabe H, Nakano T, Saito R, Akasaka D, Saito K, Ogasawara H, et al. Serotonin Improves High Fat Diet Induced Obesity in Mice. PLoS ONE. 2016;11:e0147143 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:2000
Gali Ramamoorthy T, Laverny G, Schlagowski A, Zoll J, Messaddeq N, Bornert J, et al. The transcriptional coregulator PGC-1β controls mitochondrial function and anti-oxidant defence in skeletal muscles. Nat Commun. 2015;6:10210 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; fig 5
Anderson K, Russell A, Foletta V. NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide - But not palmitate-induced toxicity. FEBS Open Bio. 2015;5:668-81 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 3
Li F, Buck D, De Winter J, Kolb J, Meng H, Birch C, et al. Nebulin deficiency in adult muscle causes sarcomere defects and muscle-type-dependent changes in trophicity: novel insights in nemaline myopathy. Hum Mol Genet. 2015;24:5219-33 pubmed publisher
  • immunohistochemistry; rat; 1:100
Oishi Y, Roy R, Ogata T, Ohira Y. Heat-Stress effects on the myosin heavy chain phenotype of rat soleus fibers during the early stages of regeneration. Muscle Nerve. 2015;52:1047-56 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:2000; fig 4
Jensen L, Andersen L, Schrøder H, Frandsen U, Sjøgaard G. Neuronal nitric oxide synthase is dislocated in type I fibers of myalgic muscle but can recover with physical exercise training. Biomed Res Int. 2015;2015:265278 pubmed publisher
  • immunohistochemistry - paraffin section; human
Koutakis P, Myers S, Cluff K, Ha D, Haynatzki G, McComb R, et al. Abnormal myofiber morphology and limb dysfunction in claudication. J Surg Res. 2015;196:172-9 pubmed publisher
  • immunocytochemistry; mouse; 1:2000; fig 3
Zhang D, Wang X, Li Y, Zhao L, Lu M, Yao X, et al. Thyroid hormone regulates muscle fiber type conversion via miR-133a1. J Cell Biol. 2014;207:753-66 pubmed publisher
  • immunohistochemistry - frozen section; rhesus macaque; 1:1500; fig 3
O Connell K, Guo W, Serra C, Beck M, Wachtman L, Hoggatt A, et al. The effects of an ActRIIb receptor Fc fusion protein ligand trap in juvenile simian immunodeficiency virus-infected rhesus macaques. FASEB J. 2015;29:1165-75 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 2
Furuya N, Ikeda S, Sato S, Soma S, Ezaki J, Oliva Trejo J, et al. PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation. Autophagy. 2014;10:631-41 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; fig 1
An C, Dong Y, Hagiwara N. Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6. BMC Dev Biol. 2011;11:59 pubmed publisher
Perrin A, Metay C, Villanova M, Carlier R, Pegoraro E, Juntas Morales R, et al. A new congenital multicore titinopathy associated with fast myosin heavy chain deficiency. Ann Clin Transl Neurol. 2020;7:846-854 pubmed publisher
Wen W, Chen X, Huang Z, Chen D, Chen H, Luo Y, et al. Resveratrol regulates muscle fiber type conversion via miR-22-3p and AMPK/SIRT1/PGC-1α pathway. J Nutr Biochem. 2020;77:108297 pubmed publisher
Rhoads T, Clark J, Gustafson G, Miller K, Conklin M, DeMuth T, et al. Molecular and Functional Networks Linked to Sarcopenia Prevention by Caloric Restriction in Rhesus Monkeys. Cell Syst. 2020;10:156-168.e5 pubmed publisher
Xu M, Chen X, Huang Z, Chen D, Chen H, Luo Y, et al. Procyanidin B2 Promotes Skeletal Slow-Twitch Myofiber Gene Expression through the AMPK Signaling Pathway in C2C12 Myotubes. J Agric Food Chem. 2020;68:1306-1314 pubmed publisher
Kusić D, Connolly J, Kainulainen H, Semenova E, Borisov O, Larin A, et al. Striated muscle-specific serine/threonine-protein kinase beta segregates with high versus low responsiveness to endurance exercise training. Physiol Genomics. 2020;52:35-46 pubmed publisher
Nicolai S, Pieraccioli M, Smirnov A, Pitolli C, Anemona L, Mauriello A, et al. ZNF281/Zfp281 is a target of miR-1 and counteracts muscle differentiation. Mol Oncol. 2020;14:294-308 pubmed publisher
Guerrero M, Carmona G, Rodas G, Cadefau J, Maestro A, Cusso R. Assessment of muscle fiber adaptation in footballers using a new ELISA assay of myosin isoforms. J Sports Med Phys Fitness. 2019;59:1828-1834 pubmed publisher
Chen X, Luo X, Chen D, Yu B, He J, Huang Z. Arginine promotes porcine type I muscle fibers formation through improvement of mitochondrial biogenesis. Br J Nutr. 2019;:1-30 pubmed publisher
Ikeda S, Mukai R, Mizushima W, Zhai P, Oka S, Nakamura M, et al. Yes-Associated Protein (YAP) Facilitates Pressure Overload-Induced Dysfunction in the Diabetic Heart. JACC Basic Transl Sci. 2019;4:611-622 pubmed publisher
Bahri O, Naldaiz Gastesi N, Kennedy D, Wheatley A, Izeta A, McCullagh K. The panniculus carnosus muscle: A novel model of striated muscle regeneration that exhibits sex differences in the mdx mouse. Sci Rep. 2019;9:15964 pubmed publisher
Cannon D, Rodewohl L, Adams V, Breen E, Bowen T. Skeletal myofiber VEGF deficiency leads to mitochondrial, structural, and contractile alterations in mouse diaphragm. J Appl Physiol (1985). 2019;127:1360-1369 pubmed publisher
Grishina E, Zmijewski P, Semenova E, Cięszczyk P, Huminska Lisowska K, Michałowska Sawczyn M, et al. Three DNA Polymorphisms Previously Identified as Markers for Handgrip Strength Are Associated With Strength in Weightlifters and Muscle Fiber Hypertrophy. J Strength Cond Res. 2019;33:2602-2607 pubmed publisher
Pickering C, Suraci B, Semenova E, Boulygina E, Kostryukova E, Kulemin N, et al. A Genome-Wide Association Study of Sprint Performance in Elite Youth Football Players. J Strength Cond Res. 2019;33:2344-2351 pubmed publisher
Deisl C, Fine M, Moe O, Hilgemann D. Hypertrophy of human embryonic stem cell-derived cardiomyocytes supported by positive feedback between Ca2+ and diacylglycerol signals. Pflugers Arch. 2019;471:1143-1157 pubmed publisher
Seaborne R, Hughes D, Turner D, Owens D, Baehr L, Górski P, et al. UBR5 is a novel E3 ubiquitin ligase involved in skeletal muscle hypertrophy and recovery from atrophy. J Physiol. 2019;597:3727-3749 pubmed publisher
Oishi Y, Ogata T, Ohira Y, Roy R. Phosphorylated ERK1/2 protein levels are closely associated with the fast fiber phenotypes in rat hindlimb skeletal muscles. Pflugers Arch. 2019;471:971-982 pubmed publisher
Winkler T, Mersmann F, von Roth P, Dietrich R, Bierbaum S, Arampatzis A. Development of a Non-invasive Methodology for the Assessment of Muscle Fibre Composition. Front Physiol. 2019;10:174 pubmed publisher
Shenkman B, Zinovyeva O, Belova S, Mirzoev T, Vilchinskaya N, Vikhlyantsev I, et al. Cellular and molecular signatures of alcohol-induced myopathy in women. Am J Physiol Endocrinol Metab. 2019;316:E967-E976 pubmed publisher
Tassinari V, De Gennaro V, La Sala G, Marazziti D, Bolasco G, Aguanno S, et al. Atrophy, oxidative switching and ultrastructural defects in skeletal muscle of the ataxia telangiectasia mouse model. J Cell Sci. 2019;132: pubmed publisher
Dmitrieva R, Lelyavina T, Komarova M, Galenko V, Ivanova O, Tikanova P, et al. Skeletal Muscle Resident Progenitor Cells Coexpress Mesenchymal and Myogenic Markers and Are Not Affected by Chronic Heart Failure-Induced Dysregulations. Stem Cells Int. 2019;2019:5690345 pubmed publisher
Sukonina V, Ma H, Zhang W, Bartesaghi S, Subhash S, Heglind M, et al. FOXK1 and FOXK2 regulate aerobic glycolysis. Nature. 2019;566:279-283 pubmed publisher
Guilherme J, Egorova E, Semenova E, Kostryukova E, Kulemin N, Borisov O, et al. The A-allele of the FTO Gene rs9939609 Polymorphism Is Associated With Decreased Proportion of Slow Oxidative Muscle Fibers and Over-represented in Heavier Athletes. J Strength Cond Res. 2019;33:691-700 pubmed publisher
Satoh M, Nomura S, Harada M, Yamaguchi T, Ko T, Sumida T, et al. High-throughput single-molecule RNA imaging analysis reveals heterogeneous responses of cardiomyocytes to hemodynamic overload. J Mol Cell Cardiol. 2019;128:77-89 pubmed publisher
Li J, Huang J, Lu J, Guo Z, Li Z, Gao H, et al. Sirtuin 1 represses PKC-ζ activity through regulating interplay of acetylation and phosphorylation in cardiac hypertrophy. Br J Pharmacol. 2019;176:416-435 pubmed publisher
Beak J, Kang H, Huang W, Myers P, Bowles D, Jetten A, et al. The nuclear receptor RORα protects against angiotensin II-induced cardiac hypertrophy and heart failure. Am J Physiol Heart Circ Physiol. 2019;316:H186-H200 pubmed publisher
Cécile P, Julien A, Andrea A, Agnès C, Cécile C, Clara T, et al. UBE2E1 Is Preferentially Expressed in the Cytoplasm of Slow-Twitch Fibers and Protects Skeletal Muscles from Exacerbated Atrophy upon Dexamethasone Treatment. Cells. 2018;7: pubmed publisher
Fontes Oliveira C, M Soares Oliveira B, Körner Z, M Harandi V, Durbeej M. Effects of metformin on congenital muscular dystrophy type 1A disease progression in mice: a gender impact study. Sci Rep. 2018;8:16302 pubmed publisher
Ferlin A, De Toni L, Agoulnik A, Lunardon G, Armani A, Bortolanza S, et al. Protective Role of Testicular Hormone INSL3 From Atrophy and Weakness in Skeletal Muscle. Front Endocrinol (Lausanne). 2018;9:562 pubmed publisher
Ekhtiari Bidhendi E, Bergh J, Zetterström P, Forsberg K, Pakkenberg B, Andersen P, et al. Mutant superoxide dismutase aggregates from human spinal cord transmit amyotrophic lateral sclerosis. Acta Neuropathol. 2018;136:939-953 pubmed publisher
Zhang W, Wan H, Feng G, Qu J, Wang J, Jing Y, et al. SIRT6 deficiency results in developmental retardation in cynomolgus monkeys. Nature. 2018;560:661-665 pubmed publisher
Begam M, Roche J. Damaged muscle fibers might masquerade as hybrid fibers - a cautionary note on immunophenotyping mouse muscle with mouse monoclonal antibodies. Eur J Histochem. 2018;62: pubmed publisher
Schaller S, Nagashima M, Schönfelder M, Sasakawa T, Schulz F, Khan M, et al. GTS-21 attenuates loss of body mass, muscle mass, and function in rats having systemic inflammation with and without disuse atrophy. Pflugers Arch. 2018;470:1647-1657 pubmed publisher
Nascimento T, Silva M, Miyabara E. BGP-15 improves contractile function of regenerating soleus muscle. J Muscle Res Cell Motil. 2018;39:25-34 pubmed publisher
Archer Lahlou E, Lan C, Jagoe R. Physiological culture conditions alter myotube morphology and responses to atrophy treatments: implications for in vitro research on muscle wasting. Physiol Rep. 2018;6:e13726 pubmed publisher
Du J, Shen L, Zhang P, Tan Z, Cheng X, Luo J, et al. The regulation of skeletal muscle fiber-type composition by betaine is associated with NFATc1/MyoD. J Mol Med (Berl). 2018;96:685-700 pubmed publisher
Mayerl S, Schmidt M, Doycheva D, Darras V, Hüttner S, Boelen A, et al. Thyroid Hormone Transporters MCT8 and OATP1C1 Control Skeletal Muscle Regeneration. Stem Cell Reports. 2018;10:1959-1974 pubmed publisher
Cykowski M, Powell S, Appel J, Arumanayagam A, Rivera A, Appel S. Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis. Acta Neuropathol Commun. 2018;6:28 pubmed publisher
Anan K, Hino S, Shimizu N, Sakamoto A, Nagaoka K, Takase R, et al. LSD1 mediates metabolic reprogramming by glucocorticoids during myogenic differentiation. Nucleic Acids Res. 2018;46:5441-5454 pubmed publisher
Wüst S, Dröse S, Heidler J, Wittig I, Klockner I, Franko A, et al. Metabolic Maturation during Muscle Stem Cell Differentiation Is Achieved by miR-1/133a-Mediated Inhibition of the Dlk1-Dio3 Mega Gene Cluster. Cell Metab. 2018;27:1026-1039.e6 pubmed publisher
Kelley K, Ben Haim L, Schirmer L, Tyzack G, Tolman M, Miller J, et al. Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength. Neuron. 2018;98:306-319.e7 pubmed publisher
Uchida T, Sakashita Y, Kitahata K, Yamashita Y, Tomida C, Kimori Y, et al. Reactive oxygen species upregulate expression of muscle atrophy-associated ubiquitin ligase Cbl-b in rat L6 skeletal muscle cells. Am J Physiol Cell Physiol. 2018;314:C721-C731 pubmed publisher
Chaweewannakorn C, Tsuchiya M, Koide M, Hatakeyama H, Tanaka Y, Yoshida S, et al. Roles of IL-1α/β in regeneration of cardiotoxin-injured muscle and satellite cell function. Am J Physiol Regul Integr Comp Physiol. 2018;315:R90-R103 pubmed publisher
Friedmann Bette B, Profit F, Gwechenberger T, Weiberg N, Parstorfer M, Weber M, et al. Strength Training Effects on Muscular Regeneration after ACL Reconstruction. Med Sci Sports Exerc. 2018;50:1152-1161 pubmed publisher
Tosic M, Allen A, Willmann D, Lepper C, Kim J, Duteil D, et al. Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells. Nat Commun. 2018;9:366 pubmed publisher
Huq E, Taylor A, Su Z, Wall C. Fiber type composition of epaxial muscles is geared toward facilitating rapid spinal extension in the leaper Galago senegalensis. Am J Phys Anthropol. 2018;166:95-106 pubmed publisher
Shenkman B, Belova S, Zinovyeva O, Samkhaeva N, Mirzoev T, Vilchinskaya N, et al. Effect of Chronic Alcohol Abuse on Anabolic and Catabolic Signaling Pathways in Human Skeletal Muscle. Alcohol Clin Exp Res. 2018;42:41-52 pubmed publisher
Gatta L, Vitiello L, Gorini S, Chiandotto S, Costelli P, Giammarioli A, et al. Modulating the metabolism by trimetazidine enhances myoblast differentiation and promotes myogenesis in cachectic tumor-bearing c26 mice. Oncotarget. 2017;8:113938-113956 pubmed publisher
Lee J, Hallock P, Burden S. Abelson tyrosine-protein kinase 2 regulates myoblast proliferation and controls muscle fiber length. elife. 2017;6: pubmed publisher
Rooney M, Porter R, Katz L, Hill E. Skeletal muscle mitochondrial bioenergetics and associations with myostatin genotypes in the Thoroughbred horse. PLoS ONE. 2017;12:e0186247 pubmed publisher
Greschik H, Duteil D, Messaddeq N, Willmann D, Arrigoni L, Sum M, et al. The histone code reader Spin1 controls skeletal muscle development. Cell Death Dis. 2017;8:e3173 pubmed publisher
Molinari F, Pin F, Gorini S, Chiandotto S, Pontecorvo L, Penna F, et al. The mitochondrial metabolic reprogramming agent trimetazidine as an 'exercise mimetic' in cachectic C26-bearing mice. J Cachexia Sarcopenia Muscle. 2017;8:954-973 pubmed publisher
Bowen T, Brauer D, Rolim N, Bækkerud F, Kricke A, Ormbostad Berre A, et al. Exercise Training Reveals Inflexibility of the Diaphragm in an Animal Model of Patients With Obesity-Driven Heart Failure With a Preserved Ejection Fraction. J Am Heart Assoc. 2017;6: pubmed publisher
Hostrup M, Onslev J, Jacobson G, Wilson R, Bangsbo J. Chronic ?2 -adrenoceptor agonist treatment alters muscle proteome and functional adaptations induced by high intensity training in young men. J Physiol. 2017;: pubmed publisher
Vicinanza C, Aquila I, Scalise M, Cristiano F, Marino F, Cianflone E, et al. Adult cardiac stem cells are multipotent and robustly myogenic: c-kit expression is necessary but not sufficient for their identification. Cell Death Differ. 2017;24:2101-2116 pubmed publisher
Jensen L, Djurtoft J, Bech R, Nielsen J, Jørgensen L, Schrøder H, et al. Influence of Resistance Training on Neuromuscular Function and Physical Capacity in ALS Patients. J Neurodegener Dis. 2017;2017:1436519 pubmed publisher
Mandai S, Furukawa S, Kodaka M, Hata Y, Mori T, Nomura N, et al. Loop diuretics affect skeletal myoblast differentiation and exercise-induced muscle hypertrophy. Sci Rep. 2017;7:46369 pubmed publisher
Pryce B, Al Zahrani K, Dufresne S, Belkina N, Labrèche C, Patino Lopez G, et al. Deletion of the Ste20-like kinase SLK in skeletal muscle results in a progressive myopathy and muscle weakness. Skelet Muscle. 2017;7:3 pubmed publisher
Vilà L, Roca C, Elias I, Casellas A, Lage R, Franckhauser S, et al. AAV-mediated Sirt1 overexpression in skeletal muscle activates oxidative capacity but does not prevent insulin resistance. Mol Ther Methods Clin Dev. 2016;5:16072 pubmed
Maesner C, Almada A, Wagers A. Established cell surface markers efficiently isolate highly overlapping populations of skeletal muscle satellite cells by fluorescence-activated cell sorting. Skelet Muscle. 2016;6:35 pubmed publisher
Sakellariou G, Pearson T, Lightfoot A, Nye G, Wells N, Giakoumaki I, et al. Mitochondrial ROS regulate oxidative damage and mitophagy but not age-related muscle fiber atrophy. Sci Rep. 2016;6:33944 pubmed publisher
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Sakakibara I, Wurmser M, Dos Santos M, Santolini M, Ducommun S, Davaze R, et al. Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle. Skelet Muscle. 2016;6:30 pubmed publisher
Thomas R, Singh A, Cowley P, Myagmar B, Montgomery M, Swigart P, et al. A Myocardial Slice Culture Model Reveals Alpha-1A-Adrenergic Receptor Signaling in the Human Heart. JACC Basic Transl Sci. 2016;1:155-167 pubmed
Lou J, Zhao D, Zhang L, Song S, Li Y, Sun F, et al. Type III Transforming Growth Factor-? Receptor Drives Cardiac Hypertrophy Through ?-Arrestin2-Dependent Activation of Calmodulin-Dependent Protein Kinase II. Hypertension. 2016;68:654-66 pubmed publisher
Böhm A, Hoffmann C, Irmler M, Schneeweiss P, Schnauder G, Sailer C, et al. TGF-? Contributes to Impaired Exercise Response by Suppression of Mitochondrial Key Regulators in Skeletal Muscle. Diabetes. 2016;65:2849-61 pubmed publisher
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Ferraro E, Pin F, Gorini S, Pontecorvo L, Ferri A, Mollace V, et al. Improvement of skeletal muscle performance in ageing by the metabolic modulator Trimetazidine. J Cachexia Sarcopenia Muscle. 2016;7:449-57 pubmed publisher
Ohnuki Y, Umeki D, Mototani Y, Shiozawa K, Nariyama M, Ito A, et al. Role of phosphodiesterase 4 expression in the Epac1 signaling-dependent skeletal muscle hypertrophic action of clenbuterol. Physiol Rep. 2016;4: pubmed publisher
Suzuki J. Short-duration intermittent hypoxia enhances endurance capacity by improving muscle fatty acid metabolism in mice. Physiol Rep. 2016;4: pubmed publisher
Shin J, Nunomiya A, Kitajima Y, Dan T, Miyata T, Nagatomi R. Prolyl hydroxylase domain 2 deficiency promotes skeletal muscle fiber-type transition via a calcineurin/NFATc1-dependent pathway. Skelet Muscle. 2016;6:5 pubmed publisher
Andersen T, Schmidt J, Pedersen M, Krustrup P, Bangsbo J. The Effects of 52 Weeks of Soccer or Resistance Training on Body Composition and Muscle Function in +65-Year-Old Healthy Males--A Randomized Controlled Trial. PLoS ONE. 2016;11:e0148236 pubmed publisher
Amoasii L, Holland W, Sanchez Ortiz E, Baskin K, Pearson M, Burgess S, et al. A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism. Genes Dev. 2016;30:434-46 pubmed publisher
Xiang F, Guo M, Yutzey K. Overexpression of Tbx20 in Adult Cardiomyocytes Promotes Proliferation and Improves Cardiac Function After Myocardial Infarction. Circulation. 2016;133:1081-92 pubmed publisher
Aoyama M, Kawase H, Bando Y, Monji A, Murohara T. Dipeptidyl Peptidase 4 Inhibition Alleviates Shortage of Circulating Glucagon-Like Peptide-1 in Heart Failure and Mitigates Myocardial Remodeling and Apoptosis via the Exchange Protein Directly Activated by Cyclic AMP 1/Ras-Related Protein 1 Axis. Circ Heart Fail. 2016;9:e002081 pubmed publisher
Dearth C, Slivka P, Stewart S, Keane T, Tay J, Londono R, et al. Inhibition of COX1/2 alters the host response and reduces ECM scaffold mediated constructive tissue remodeling in a rodent model of skeletal muscle injury. Acta Biomater. 2016;31:50-60 pubmed publisher
Quattrocelli M, Swinnen M, Giacomazzi G, Camps J, Barthélemy I, Ceccarelli G, et al. Mesodermal iPSC-derived progenitor cells functionally regenerate cardiac and skeletal muscle. J Clin Invest. 2015;125:4463-82 pubmed publisher
Sierra E, Fernández A, Espinosa de los Monteros A, Díaz Delgado J, Bernaldo de Quirós Y, García Álvarez N, et al. Comparative histology of muscle in free ranging cetaceans: shallow versus deep diving species. Sci Rep. 2015;5:15909 pubmed publisher
Sebastian S, Goulding L, Kuchipudi S, Chang K. Extended 2D myotube culture recapitulates postnatal fibre type plasticity. BMC Cell Biol. 2015;16:23 pubmed publisher
Gul R, Mahmood A, Lück C, Lum Naihe K, Alfadda A, Speth R, et al. Regulation of cardiac miR-208a, an inducer of obesity, by rapamycin and nebivolol. Obesity (Silver Spring). 2015;23:2251-9 pubmed publisher
Sakuma M, Gorski G, Sheu S, Lee S, Barrett L, Singh B, et al. Lack of motor recovery after prolonged denervation of the neuromuscular junction is not due to regenerative failure. Eur J Neurosci. 2016;43:451-62 pubmed publisher
Mizunoya W, Miyahara H, Okamoto S, Akahoshi M, Suzuki T, Do M, et al. Improvement of Endurance Based on Muscle Fiber-Type Composition by Treatment with Dietary Apple Polyphenols in Rats. PLoS ONE. 2015;10:e0134303 pubmed publisher
Steinbacher P, Feichtinger R, Kedenko L, Kedenko I, Reinhardt S, Schönauer A, et al. The single nucleotide polymorphism Gly482Ser in the PGC-1α gene impairs exercise-induced slow-twitch muscle fibre transformation in humans. PLoS ONE. 2015;10:e0123881 pubmed publisher
Reeves A, Spears W, Du J, Tan K, Wagers A, Lesser C. Engineering Escherichia coli into a protein delivery system for mammalian cells. ACS Synth Biol. 2015;4:644-54 pubmed publisher
McAleer C, Rumsey J, Stancescu M, Hickman J. Functional myotube formation from adult rat satellite cells in a defined serum-free system. Biotechnol Prog. 2015;31:997-1003 pubmed publisher
Bowen T, Rolim N, Fischer T, Baekkerud F, Medeiros A, Werner S, et al. Heart failure with preserved ejection fraction induces molecular, mitochondrial, histological, and functional alterations in rat respiratory and limb skeletal muscle. Eur J Heart Fail. 2015;17:263-72 pubmed publisher
Matheny R, Riddle Kottke M, Leandry L, Lynch C, Abdalla M, Geddis A, et al. Role of phosphoinositide 3-OH kinase p110β in skeletal myogenesis. Mol Cell Biol. 2015;35:1182-96 pubmed publisher
Henagan T, Stefanska B, Fang Z, Navard A, Ye J, Lenard N, et al. Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning. Br J Pharmacol. 2015;172:2782-98 pubmed publisher
Boettger T, Wüst S, Nolte H, Braun T. The miR-206/133b cluster is dispensable for development, survival and regeneration of skeletal muscle. Skelet Muscle. 2014;4:23 pubmed publisher
Qi Y, Zhu Q, Zhang K, THOMAS C, Wu Y, Kumar R, et al. Activation of Foxo1 by insulin resistance promotes cardiac dysfunction and β-myosin heavy chain gene expression. Circ Heart Fail. 2015;8:198-208 pubmed publisher
Besser J, Malan D, Wystub K, Bachmann A, Wietelmann A, Sasse P, et al. MiRNA-1/133a clusters regulate adrenergic control of cardiac repolarization. PLoS ONE. 2014;9:e113449 pubmed publisher
Ehlers M, Celona B, Black B. NFATc1 controls skeletal muscle fiber type and is a negative regulator of MyoD activity. Cell Rep. 2014;8:1639-1648 pubmed publisher
Skovgaard C, Christensen P, Larsen S, Andersen T, Thomassen M, Bangsbo J. Concurrent speed endurance and resistance training improves performance, running economy, and muscle NHE1 in moderately trained runners. J Appl Physiol (1985). 2014;117:1097-109 pubmed publisher
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product information
Product No. :
M8421
Product Name :
Monoclonal Anti-Myosin (Skeletal, Slow) antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
NOQ7.5.4D
Applications/Description :
Suitable for electron microscopy; western blot: 1:5,000 using extract of rat or rabbit tongue; radioimmunoassay; indirect ELISA; immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:4,000 using protease-digested, sections of r
Species Reactivity :
sheep, hamster, goat, rabbit, human, canine, bovine, rat, feline, pig, guinea pig, mouse, chicken
Isotype :
IgG1
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA