This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
α-Methyl-L-tyrosine
catalog :
M8131
citations: 28
Reference
Kim M, Achmad A, Higuchi T, Arisaka Y, Yokoo H, Yokoo S, et al. Effects of intratumoral inflammatory process on 18F-FDG uptake: pathologic and comparative study with 18F-fluoro-α-methyltyrosine PET/CT in oral squamous cell carcinoma. J Nucl Med. 2015;56:16-21 pubmed publisher
Lee Y, Lin C, Jiang H, Depaul M, Lin V, Silver J. Nerve regeneration restores supraspinal control of bladder function after complete spinal cord injury. J Neurosci. 2013;33:10591-606 pubmed publisher
Avelar A, Juliano S, Garris P. Amphetamine augments vesicular dopamine release in the dorsal and ventral striatum through different mechanisms. J Neurochem. 2013;125:373-85 pubmed publisher
Romanova I, Chesnokova A, Mikhrina A. [Immunohistochemical study of CART-peptide in striato-nigral projections at dopamine loss]. Ross Fiziol Zh Im I M Sechenova. 2012;98:980-9 pubmed
Svob Strac D, Muck Seler D, Pivac N. The involvement of noradrenergic mechanisms in the suppressive effects of diazepam on the hypothalamic-pituitary-adrenal axis activity in female rats. Croat Med J. 2012;53:214-23 pubmed
Saifetyarova Y, Sapronova A, Ugryumov M. Endocrine function of dopaminergic neurons of the whole rat brain in ontogeny: control of prolactin secretion. Dokl Biol Sci. 2012;443:81-3 pubmed publisher
Melnikova V, Afanasyeva M, Voronova S, Zakharova L. The effect of catecholamine deficit on the development of the immune system in rats. Dokl Biol Sci. 2012;443:68-70 pubmed publisher
Grob S, Pizzagalli D, Dutra S, Stern J, Mörgeli H, Milos G, et al. Dopamine-related deficit in reward learning after catecholamine depletion in unmedicated, remitted subjects with bulimia nervosa. Neuropsychopharmacology. 2012;37:1945-52 pubmed publisher
Lima M, Andersen M, Reksidler A, Ferraz A, Vital M, Tufik S. Paradoxical sleep deprivation modulates tyrosine hydroxylase expression in the nigrostriatal pathway and attenuates motor deficits induced by dopaminergic depletion. CNS Neurol Disord Drug Targets. 2012;11:359-68 pubmed
Linck V, Costa Campos L, Pilz L, Garcia C, Elisabetsky E. AMPA glutamate receptors mediate the antidepressant-like effects of N-acetylcysteine in the mouse tail suspension test. Behav Pharmacol. 2012;23:171-7 pubmed publisher
Yigiter M, Yildiz A, Polat B, Alp H, Keles O, Salman A, et al. The protective effects of metyrosine, lacidipine, clonidine, and moxonidine on kidney damage induced by unilateral ureteral obstruction in rats. Surg Today. 2012;42:1051-60 pubmed publisher
Braak B, Booij J, Klooker T, van den Wijngaard R, Boeckxstaens G. The dopaminergic system in patients with functional dyspepsia analysed by single photon emission computed tomography (SPECT) and an alpha-methyl-para-tyrosine (AMPT) challenge test. Eur J Nucl Med Mol Imaging. 2012;39:642-50 pubmed publisher
Chaube R, Singh R, Joy K. Estrogen regulation of brain vasotocin secretion in the catfish Heteropneustes fossilis: an interaction with catecholaminergic system. Gen Comp Endocrinol. 2012;175:206-13 pubmed publisher
Kawaura K, Miki R, Urashima Y, Kawahara R, Soeda F, Shirasaki T, et al. Pharmacological mechanisms of antidepressant-like effect of tipepidine in the forced swimming test. Behav Brain Res. 2012;226:381-5 pubmed publisher
Chaube R, Joy K. Estradiol-17β modulates dose-dependently hypothalamic tyrosine hydroxylase activity inhibited by α-methylparatyrosine in the catfish Heteropneustes fossilis. Endocrine. 2011;40:394-9 pubmed publisher
Albayrak Y, Saglam M, Yildirim K, Karatay S, Polat B, Uslu T, et al. Effects of epinephrine and cortisol on the analgesic activity of metyrosine in rats. Arch Pharm Res. 2011;34:1519-25 pubmed publisher
Ugrumov M, Saifetyarova J, Lavrentieva A, Sapronova A. Developing brain as an endocrine organ: secretion of dopamine. Mol Cell Endocrinol. 2012;348:78-86 pubmed publisher
Charron G, Doudnikoff E, Laux A, Berthet A, Porras G, Canron M, et al. Endogenous morphine-like compound immunoreactivity increases in parkinsonism. Brain. 2011;134:2321-38 pubmed publisher
Vargovic P, Ukropec J, Laukova M, Cleary S, Manz B, Pacak K, et al. Adipocytes as a new source of catecholamine production. FEBS Lett. 2011;585:2279-84 pubmed publisher
Bromek E, Haduch A, Gołembiowska K, Daniel W. Cytochrome P450 mediates dopamine formation in the brain in vivo. J Neurochem. 2011;118:806-15 pubmed publisher
Chen M, Vijay V, Shi Q, Liu Z, Fang H, Tong W. FDA-approved drug labeling for the study of drug-induced liver injury. Drug Discov Today. 2011;16:697-703 pubmed publisher
Kong F, Ali M, Zhang Y, Oh C, Yu D, Chanda M, et al. Synthesis and evaluation of amino acid-based radiotracer 99mTc-N4-AMT for breast cancer imaging. J Biomed Biotechnol. 2011;2011:276907 pubmed publisher
Iwata K, Kinoshita M, Susaki N, Uenoyama Y, Tsukamura H, Maeda K. Central injection of ketone body suppresses luteinizing hormone release via the catecholaminergic pathway in female rats. J Reprod Dev. 2011;57:379-84 pubmed
Kurjanova E, Teplyj D. Influence of central neurotransmitters on heart rate variability in outbred rats at rest and during acute stress: nature of very-low-wave spectrum component revisited. Bull Exp Biol Med. 2010;149:10-3 pubmed
Kaira K, Oriuchi N, Yanagitani N, Sunaga N, Ishizuka T, Mori M, et al. Assessment of therapy response in lung cancer with ¹⁸F-α-methyl tyrosine PET. AJR Am J Roentgenol. 2010;195:1204-11 pubmed publisher
Chaube R, Joy K. Inhibition of hCG-induced spawning by alpha-methylparatyrosine, a tyrosine hydroxylase inhibitor, in the catfish Heteropneustes fossilis (Bloch). Indian J Exp Biol. 2010;48:549-53 pubmed
Hsieh Y, Yang S, Chen P, Chu S, Chen C, Kuo D. Knocking down the transcript of protein kinase C-lambda modulates hypothalamic glutathione peroxidase, melanocortin receptor and neuropeptide Y gene expression in amphetamine-treated rats. J Psychopharmacol. 2011;25:982-94 pubmed publisher
Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed
product information
Catalog Number :
M8131
Product Name :
α-Methyl-L-tyrosine
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98% (TLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA