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product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
17α-Methyltestosterone
catalog :
M7252
citations: 54
Reference
Larkins C, Enriquez A, Cohn M. Spatiotemporal dynamics of androgen signaling underlie sexual differentiation and congenital malformations of the urethra and vagina. Proc Natl Acad Sci U S A. 2016;113:E7510-E7517 pubmed
Shigeri Y, Yasuda A, Sakai M, Ikeda S, Arakawa R, Sato H, et al. Hydrazide and hydrazine reagents as reactive matrices for matrix-assisted laser desorption/ionization mass spectrometry to detect steroids with carbonyl groups. Eur J Mass Spectrom (Chichester). 2015;21:79-90 pubmed publisher
Watson L, Potter R, Murphy C, Gibbs R. The Development and Single-Laboratory Validation of a Method for the Determination of Steroid Residues in Fish and Fish Products. J AOAC Int. 2015;98:580-587 pubmed publisher
Silva A, Ebrahimi Najafadabi H, McGinitie T, Casilli A, Pereira H, Aquino Neto F, et al. Thermodynamic-based retention time predictions of endogenous steroids in comprehensive two-dimensional gas chromatography. Anal Bioanal Chem. 2015;407:4091-9 pubmed publisher
Balcells G, Pozo O, Esquivel A, Kotronoulas A, Joglar J, Segura J, et al. Screening for anabolic steroids in sports: analytical strategy based on the detection of phase I and phase II intact urinary metabolites by liquid chromatography tandem mass spectrometry. J Chromatogr A. 2015;1389:65-75 pubmed publisher
Ye M, Tang L, Luo M, Zhou J, Guo B, Liu Y, et al. Size- and time-dependent alteration in metabolic activities of human hepatic cytochrome P450 isozymes by gold nanoparticles via microsomal coincubations. Nanoscale Res Lett. 2014;9:642 pubmed publisher
Wang J, Yang R, Yang W, Liu X, Xing Y, Xu Y. IRMS detection of testosterone manipulated with 13C labeled standards in human urine by removing the labeled 13C. Anal Chim Acta. 2014;852:146-52 pubmed publisher
Sobolevsky T, Prasolov I, Rodchenkov G. Study on the phase I metabolism of novel synthetic cannabinoids, APICA and its fluorinated analogue. Drug Test Anal. 2015;7:131-42 pubmed publisher
Storey J, Clark S, Johnson A, Andersen W, Turnipseed S, Lohne J, et al. Analysis of sulfonamides, trimethoprim, fluoroquinolones, quinolones, triphenylmethane dyes and methyltestosterone in fish and shrimp using liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;972:38-47 pubmed publisher
Ruokolainen M, Valkonen M, Sikanen T, Kotiaho T, Kostiainen R. Imitation of phase I oxidative metabolism of anabolic steroids by titanium dioxide photocatalysis. Eur J Pharm Sci. 2014;65:45-55 pubmed publisher
Bussche J, Decloedt A, Van Meulebroek L, De Clercq N, Lock S, Stahl Zeng J, et al. A novel approach to the quantitative detection of anabolic steroids in bovine muscle tissue by means of a hybrid quadrupole time-of-flight-mass spectrometry instrument. J Chromatogr A. 2014;1360:229-39 pubmed publisher
Andersen D, Linnet K. Screening for anabolic steroids in urine of forensic cases using fully automated solid phase extraction and LC-MS-MS. J Anal Toxicol. 2014;38:637-44 pubmed publisher
Wang J, Yang R, Yang W, Liu X, Xing Y. Impact of progesterone administration on doping test of endogenous steroids. Anal Bioanal Chem. 2014;406:6061-7 pubmed publisher
Mawaribuchi S, Ikeda N, Fujitani K, Ito Y, Onuma Y, Komiya T, et al. Cell-mass structures expressing the aromatase gene Cyp19a1 lead to ovarian cavities in Xenopus laevis. Endocrinology. 2014;155:3996-4005 pubmed publisher
Mi X, Li S, Li Y, Wang K, Zhu D, Chen G. Quantitative determination of 26 steroids in eggs from various species using liquid chromatography-triple quadrupole-mass spectrometry. J Chromatogr A. 2014;1356:54-63 pubmed publisher
Verma S, Alim A. Differential activity of stanniocalcin in male and female fresh water teleost Mastacembelus armatus (Lacepede) during gonadal maturation. PLoS ONE. 2014;9:e101439 pubmed publisher
Raro M, Portolés T, Sancho J, Pitarch E, Hernandez F, Marcos J, et al. Mass spectrometric behavior of anabolic androgenic steroids using gas chromatography coupled to atmospheric pressure chemical ionization source. Part I: ionization. J Mass Spectrom. 2014;49:509-21 pubmed publisher
Guo F, Shao J, Liu Q, Shi J, Jiang G. Automated and sensitive determination of four anabolic androgenic steroids in urine by online turbulent flow solid-phase extraction coupled with liquid chromatography-tandem mass spectrometry: a novel approach for clinical monitoring and doping contr. Talanta. 2014;125:432-8 pubmed publisher
Liñán Cabello M, Robles Basto C, Mena herrera A. Somatic growth effects of intramuscular injection of growth hormone in androgen-treated juvenile Nile tilapia, Oreochromis niloticus (Perciformes: Cichlidae). Rev Biol Trop. 2013;61:203-12 pubmed
Park C, Soyano K, Kiros S, Kitamura T, Minamiyama M, Suzuki Y. Transient effects of methyltestosterone injection on different reproductive parameters of the hermaphrodite fish Kryptolebias marmoratus. Ecotoxicology. 2013;22:1145-54 pubmed publisher
Krysiak R, Okopien B. Methyltestosterone-induced transient hyperthyroidism in a hypothyroid patient. Acta Clin Belg. 2013;68:65-7 pubmed
Musharraf S, Ali A, Khan N, Yousuf M, Choudhary M, Atta Ur Rahman -. Tandem mass spectrometry approach for the investigation of the steroidal metabolism: structure-fragmentation relationship (SFR) in anabolic steroids and their metabolites by ESI-MS/MS analysis. Steroids. 2013;78:171-81 pubmed publisher
Gomez C, Pozo O, Marcos J, Segura J, Ventura R. Alternative long-term markers for the detection of methyltestosterone misuse. Steroids. 2013;78:44-52 pubmed publisher
Singh A. Introduction of modern endocrine techniques for the production of monosex population of fishes. Gen Comp Endocrinol. 2013;181:146-55 pubmed publisher
Oberlander J, Porter D, Onakomaiya M, Penatti C, Vithlani M, Moss S, et al. Estrous cycle variations in GABA(A) receptor phosphorylation enable rapid modulation by anabolic androgenic steroids in the medial preoptic area. Neuroscience. 2012;226:397-410 pubmed publisher
Han Y, Ma Q, Lu J, Xue Y, Xue C. Optimisation for subcritical fluid extraction of 17-methyltestosterone with 1,1,1,2-tetrafluoroethane for HPLC analysis. Food Chem. 2012;135:2988-93 pubmed publisher
Júnior R, Vargas L, Valentim Zabott M, Ribeiro R, Da Silva A, Otutumi L. Morphometry of white muscle fibers and performance of Nile tilapia (Oreochromis niloticus) fingerlings treated with methyltestosterone or a homeopathic complex. Homeopathy. 2012;101:154-8 pubmed publisher
Shi Y, Liu X, Zhang H, Zhang Y, Lu D, Lin H. Molecular identification of an androgen receptor and its changes in mRNA levels during 17?-methyltestosterone-induced sex reversal in the orange-spotted grouper Epinephelus coioides. Comp Biochem Physiol B Biochem Mol Biol. 2012;163:43-50 pubmed publisher
Amarasinghe K, Chu P, EVANS E, Reimschuessel R, Hasbrouck N, Jayasuriya H. Development of a fast screening and confirmatory method by liquid chromatography-quadrupole-time-of-flight mass spectrometry for glucuronide-conjugated methyltestosterone metabolite in tilapia. J Agric Food Chem. 2012;60:5084-8 pubmed publisher
Homklin S, Ong S, Limpiyakorn T. Degradation of 17?-methyltestosterone by Rhodococcus sp. and Nocardioides sp. isolated from a masculinizing pond of Nile tilapia fry. J Hazard Mater. 2012;221-222:35-44 pubmed publisher
Hogan N, Gallant M, van den Heuvel M. Exposure to the pesticide linuron affects androgen-dependent gene expression in the three-spined stickleback (Gasterosteus aculeatus). Environ Toxicol Chem. 2012;31:1391-5 pubmed publisher
Phumyu N, Boonanuntanasarn S, Jangprai A, Yoshizaki G, Na Nakorn U. Pubertal effects of 17?-methyltestosterone on GH-IGF-related genes of the hypothalamic-pituitary-liver-gonadal axis and other biological parameters in male, female and sex-reversed Nile tilapia. Gen Comp Endocrinol. 2012;177:278-92 pubmed publisher
Schmidt K, Hackenberg R, Stachel C, Gowik P. Endogenous and synthetic steroids in bovine urine--preparation of in-house reference material, stability studies and results of a proficiency test. Anal Chim Acta. 2012;717:85-91 pubmed publisher
Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W. Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS Comput Biol. 2011;7:e1002310 pubmed publisher
Cai Q, Feng J, Zhang Y, Peng Y, Xue L, Du Z. [Determination of 12 steroid hormone residues in pig tissues by liquid chromatography-tandem mass spectrometry combining with library search]. Se Pu. 2011;29:712-7 pubmed
Rogol A. How does an anabolic/androgenic steroid get banned from sport competition?. Endocrinology. 2011;152:4473-4 pubmed publisher
Powers J, Boyd A. Right-sided vascular lesions: challenge. Am J Dermatopathol. 2012;34:833 pubmed publisher
Parr M, Blatt C, Zierau O, Hess C, Gutschow M, Fusshöller G, et al. Endocrine characterization of the designer steroid methyl-1-testosterone: investigations on tissue-specific anabolic-androgenic potency, side effects, and metabolism. Endocrinology. 2011;152:4718-28 pubmed publisher
Stange D, Sieratowicz A, Horres R, Oehlmann J. Freshwater mudsnail (Potamopyrgus antipodarum) estrogen receptor: identification and expression analysis under exposure to (xeno-)hormones. Ecotoxicol Environ Saf. 2012;75:94-101 pubmed publisher
Jiang W, Yang Y, Zhao D, Liu X, Duan J, Xie S, et al. Effects of sexual steroids on the expression of foxl2 in Gobiocypris rarus. Comp Biochem Physiol B Biochem Mol Biol. 2011;160:187-93 pubmed publisher
Penatti C, Oberlander J, Davis M, Porter D, Henderson L. Chronic exposure to anabolic androgenic steroids alters activity and synaptic function in neuroendocrine control regions of the female mouse. Neuropharmacology. 2011;61:653-64 pubmed publisher
Hu X, Liu X, Zhang H, Zhang Y, Li S, Sang Q, et al. Expression profiles of gonadotropins and their receptors during 17?-methyltestosterone implantation-induced sex change in the orange-spotted grouper (Epinephelus coioides). Mol Reprod Dev. 2011;78:376-90 pubmed publisher
Hemmer M, Salinas K, Harris P. Application of protein expression profiling to screen chemicals for androgenic activity. Aquat Toxicol. 2011;103:71-8 pubmed publisher
Mortensen A, Letcher R, Cangialosi M, Chu S, Arukwe A. Tissue bioaccumulation patterns, xenobiotic biotransformation and steroid hormone levels in Atlantic salmon (Salmo salar) fed a diet containing perfluoroactane sulfonic or perfluorooctane carboxylic acids. Chemosphere. 2011;83:1035-44 pubmed publisher
Homklin S, Ong S, Limpiyakorn T. Biotransformation of 17α-methyltestosterone in sediment under different electron acceptor conditions. Chemosphere. 2011;82:1401-7 pubmed publisher
Uehara T, Ono A, Maruyama T, Kato I, Yamada H, Ohno Y, et al. The Japanese toxicogenomics project: application of toxicogenomics. Mol Nutr Food Res. 2010;54:218-27 pubmed publisher
Fourches D, Barnes J, Day N, Bradley P, Reed J, Tropsha A. Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chem Res Toxicol. 2010;23:171-83 pubmed publisher
Attardi B, Pham T, Radler L, Burgenson J, Hild S, Reel J. Dimethandrolone (7alpha,11beta-dimethyl-19-nortestosterone) and 11beta-methyl-19-nortestosterone are not converted to aromatic A-ring products in the presence of recombinant human aromatase. J Steroid Biochem Mol Biol. 2008;110:214-22 pubmed publisher
Alvarez Ginarte Y, Crespo Otero R, Marrero Ponce Y, Noheda Marin P, Garcia de la Vega J, Montero Cabrera L, et al. Chemometric and chemoinformatic analyses of anabolic and androgenic activities of testosterone and dihydrotestosterone analogues. Bioorg Med Chem. 2008;16:6448-59 pubmed publisher
Cherkasov A, Ban F, Santos Filho O, Thorsteinson N, Fallahi M, Hammond G. An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin. J Med Chem. 2008;51:2047-56 pubmed publisher
Lill M, Winiger F, Vedani A, Ernst B. Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. J Med Chem. 2005;48:5666-74 pubmed
Phillips E, Ryan S, Ferrari R, Green C. Estratest and Estratest HS (esterified estrogens and methyltestosterone) therapy: a summary of safety surveillance data, January 1989 to August 2002. Clin Ther. 2003;25:3027-43 pubmed
Lee S, Hutson J. Effect of androgens on the cranial suspensory ligament and ovarian position. Anat Rec. 1999;255:306-15 pubmed
Herfeld S, Moller P. Effects of 17alpha-methyltestosterone on sexually dimorphic characters in the weakly discharging electric fish, Brienomyrus niger (Günther, 1866) (Mormyridae): electric organ discharge, ventral body wall indentation, and anal-Fin ray bone expansion. Horm Behav. 1998;34:303-19 pubmed
product information
Catalog Number :
M7252
Product Name :
17α-Methyltestosterone
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
solid (photosensitive)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA