This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Methoxamine hydrochloride
catalog :
M6524
citations: 37
Reference
Ray P, Chin A, Worley K, Fan J, Kaur G, Wu M, et al. Intrinsic cellular chirality regulates left-right symmetry breaking during cardiac looping. Proc Natl Acad Sci U S A. 2018;115:E11568-E11577 pubmed publisher
Mori A, Hanada M, Sakamoto K, Nakahara T, Ishii K. Impaired retinal vasodilator response to acetylcholine in a rat model of NMDA-induced retinal degeneration. J Pharmacol Sci. 2015;127:211-6 pubmed publisher
Velásquez Martínez M, Vázquez Torres R, Rojas L, SANABRIA P, Jiménez Rivera C. Alpha-1 adrenoreceptors modulate GABA release onto ventral tegmental area dopamine neurons. Neuropharmacology. 2015;88:110-21 pubmed publisher
Cuesta C, García Pedraza J, García M, Villalón C, Morán A. Role of 5-HT7 receptors in the inhibition of the vasodepressor sensory CGRPergic outflow in pithed rats. Vascul Pharmacol. 2014;63:4-12 pubmed publisher
Chang K, Ho P. Gas chromatography time-of-flight mass spectrometry (GC-TOF-MS)-based metabolomics for comparison of caffeinated and decaffeinated coffee and its implications for Alzheimer's disease. PLoS ONE. 2014;9:e104621 pubmed publisher
Killian L, Docherty J. Cardiovascular stimulant actions of bupropion in comparison to cocaine in the rat. Eur J Pharmacol. 2014;735:32-7 pubmed publisher
Vidal C, Grassin Delyle S, Devillier P, Naline E, Lansac E, Menasche P, et al. Effect of severe acidosis on vasoactive effects of epinephrine and norepinephrine in human distal mammary artery. J Thorac Cardiovasc Surg. 2014;147:1698-705 pubmed publisher
Ulu S. Determination of methoxamine in human plasma and urine by a validated HPLC-fluorescence detection method. J AOAC Int. 2013;96:987-90 pubmed
Cobzac S, Casoni D, Sarbu C. Lipophilicity of amine neurotransmitter precursors, metabolites and related drugs estimated on various TLC plates. J Chromatogr Sci. 2014;52:1095-103 pubmed publisher
Abdulla M, Sattar M, Abdullah N, Johns E. The effect of high-fructose intake on the vasopressor response to angiotensin II and adrenergic agonists in Sprague-Dawley rats. Pak J Pharm Sci. 2013;26:727-32 pubmed
Tep Areenan P, Suksamrarn S. Mechanisms of vasorelaxation to gamma-mangostin in the rat aorta. J Med Assoc Thai. 2012;95 Suppl 12:S63-8 pubmed
Nusuetrong P, Sotanaphun U, Tep Areenan P. Effects of Phikud Navakot extract on vascular reactivity in the isolated rat aorta. J Med Assoc Thai. 2012;95 Suppl 12:S1-7 pubmed
Dar M, Al Rejaie S. Tonic modulatory role of mouse cerebellar α- and β-adrenergic receptors in the expression of ethanol-induced ataxia: role of AC-cAMP. Behav Brain Res. 2013;241:154-60 pubmed publisher
Hernandez Guerra M, de Ganzo Z, González Méndez Y, Salido E, Abreu P, Moreno M, et al. Chronic intermittent hypoxia aggravates intrahepatic endothelial dysfunction in cirrhotic rats. Hepatology. 2013;57:1564-74 pubmed publisher
Herath C, Mak K, Burrell L, Angus P. Angiotensin-(1-7) reduces the perfusion pressure response to angiotensin II and methoxamine via an endothelial nitric oxide-mediated pathway in cirrhotic rat liver. Am J Physiol Gastrointest Liver Physiol. 2013;304:G99-108 pubmed publisher
Francque S, Laleman W, Verbeke L, Van Steenkiste C, Casteleyn C, Kwanten W, et al. Increased intrahepatic resistance in severe steatosis: endothelial dysfunction, vasoconstrictor overproduction and altered microvascular architecture. Lab Invest. 2012;92:1428-39 pubmed publisher
Tsutsui K, Hayami N, Kunishima T, Sugiura A, Mikamo T, Kanamori K, et al. Dexmedetomidine and clonidine inhibit ventricular tachyarrhythmias in a rabbit model of acquired long QT syndrome. Circ J. 2012;76:2343-7 pubmed
Yang Y, Huang Y, Tsai T, Hou M, Lee F, Lee S, et al. Kupffer cell depletion attenuates leptin-mediated methoxamine-stimulated portal perfusion pressure and thromboxane A2 release in a rodent model of NASH-cirrhosis. Clin Sci (Lond). 2012;123:669-80 pubmed publisher
Wang J, Bouwmeester J, Belenkie I, Shrive N, Tyberg J. Alterations in aortic wave reflection with vasodilation and vasoconstriction in anaesthetized dogs. Can J Cardiol. 2013;29:243-53 pubmed publisher
Saigusa T, Aono Y, Uchida T, Takada K, Verheij M, Koshikawa N, et al. The α₁-, but not α₂-, adrenoceptor in the nucleus accumbens plays an inhibitory role upon the accumbal noradrenaline and dopamine efflux of freely moving rats. Eur J Pharmacol. 2012;688:35-41 pubmed publisher
Fujii H, Takatori S, Zamami Y, Hashikawa Hobara N, Miyake N, Tangsucharit P, et al. Adrenergic stimulation-released 5-HT stored in adrenergic nerves inhibits CGRPergic nerve-mediated vasodilatation in rat mesenteric resistance arteries. Br J Pharmacol. 2012;166:2084-94 pubmed publisher
Huang S, Treviño M, He K, Ardiles A, Pasquale R, Guo Y, et al. Pull-push neuromodulation of LTP and LTD enables bidirectional experience-induced synaptic scaling in visual cortex. Neuron. 2012;73:497-510 pubmed publisher
Jin H, Sun P, Takatori S, Koyama T, Zamami Y, Tangsucharit P, et al. Involvement of perivascular nerves and transient receptor potential vanilloid 1 (TRPV1) in vascular responses to histamine in rat mesenteric resistance arteries. Eur J Pharmacol. 2012;680:73-80 pubmed publisher
Greenhill L. Cautious reassurance: cardiovascular risk in the context of stimulant use. J Am Acad Child Adolesc Psychiatry. 2012;51:132-3 pubmed publisher
Decher N, Wemhöner K, Rinné S, Netter M, Zuzarte M, Aller M, et al. Knock-out of the potassium channel TASK-1 leads to a prolonged QT interval and a disturbed QRS complex. Cell Physiol Biochem. 2011;28:77-86 pubmed publisher
Filli L, Zörner B, Weinmann O, Schwab M. Motor deficits and recovery in rats with unilateral spinal cord hemisection mimic the Brown-Sequard syndrome. Brain. 2011;134:2261-73 pubmed publisher
Nalos L, Varkevisser R, Jonsson M, Houtman M, Beekman J, van der Nagel R, et al. Comparison of the IKr blockers moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals lack of specificity of isolated cardiomyocytes. Br J Pharmacol. 2012;165:467-78 pubmed publisher
Mackenzie L, Heaton J, Adams M. Impact of systemically active neurohumoral factors on the erectile response of the rat. J Sex Med. 2011;8:2461-71 pubmed publisher
Thiele R, Nemergut E, Lynch C. The physiologic implications of isolated alpha(1) adrenergic stimulation. Anesth Analg. 2011;113:284-96 pubmed publisher
Frigon A, Thompson C, Johnson M, Manuel M, Hornby T, Heckman C. Extra forces evoked during electrical stimulation of the muscle or its nerve are generated and modulated by a length-dependent intrinsic property of muscle in humans and cats. J Neurosci. 2011;31:5579-88 pubmed publisher
Abdulla M, Sattar M, Johns E, Abdullah N, Khan M. Evidence for the role of ?1A-adrenoceptor subtype in the control of renal haemodynamics in fructose-fed Sprague-Dawley rat. Eur J Nutr. 2011;50:689-97 pubmed publisher
Abdulla M, Sattar M, Abdullah N, Khan M, Anand Swarup K, Johns E. The effect of losartan and carvedilol on vasopressor responses to adrenergic agonists and angiotensin II in the systemic circulation of Sprague Dawley rats. Auton Autacoid Pharmacol. 2011;31:13-20 pubmed publisher
Li J, Zhu Y, Geipel P. Pulse pressure, arterial compliance and wave reflection under differential vasoactive and mechanical loading. Cardiovasc Eng. 2010;10:170-5 pubmed publisher
Inaba H, Hayami N, Ajiki K, Kunishima T, Watanabe H, Tsutsui K, et al. Deep anesthesia suppresses ventricular tachyarrhythmias in rabbit model of the acquired long QT syndrome. Circ J. 2011;75:89-93 pubmed
Peng Y, Chang K. Acute effects of methoxamine on left ventricular-arterial coupling in streptozotocin-diabetic rats: a pressure-volume analysis. Can J Physiol Pharmacol. 2000;78:415-22 pubmed
Hussain M, Marshall I. Alpha(1)-adrenoceptor subtypes mediating contractions of the rat mesenteric artery. Eur J Pharmacol. 2000;395:69-76 pubmed
Lee R, Heckman C. Enhancement of bistability in spinal motoneurons in vivo by the noradrenergic alpha1 agonist methoxamine. J Neurophysiol. 1999;81:2164-74 pubmed
product information
Catalog Number :
M6524
Product Name :
Methoxamine hydrochloride
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA