This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Melatonin
catalog :
M5250
citations: 417
Reference
Szeiffova Bacova B, Viczenczová C, Andelova K, Sykora M, Chaudagar K, Barancik M, et al. Antiarrhythmic Effects of Melatonin and Omega-3 Are Linked with Protection of Myocardial Cx43 Topology and Suppression of Fibrosis in Catecholamine Stressed Normotensive and Hypertensive Rats. Antioxidants (Basel). 2020;9: pubmed publisher
Chen F, Jiang G, Liu H, Li Z, Pei Y, Wang H, et al. Melatonin alleviates intervertebral disc degeneration by disrupting the IL-1β/NF-κB-NLRP3 inflammasome positive feedback loop. Bone Res. 2020;8:10 pubmed publisher
Li C, He X, Huang Z, Han L, Wu X, Li L, et al. Melatonin ameliorates the advanced maternal age-associated meiotic defects in oocytes through the SIRT2-dependent H4K16 deacetylation pathway. Aging (Albany NY). 2020;12:1610-1623 pubmed publisher
Yang Z, Bao Y, Chen W, He Y. Melatonin exerts neuroprotective effects by attenuating astro- and microgliosis and suppressing inflammatory response following spinal cord injury. Neuropeptides. 2020;79:102002 pubmed publisher
Gao T, Wang Z, Cao J, Dong Y, Chen Y. Melatonin alleviates oxidative stress in sleep deprived mice: Involvement of small intestinal mucosa injury. Int Immunopharmacol. 2020;78:106041 pubmed publisher
Abo Taleb H, Alghamdi B. Neuroprotective Effects of Melatonin during Demyelination and Remyelination Stages in a Mouse Model of Multiple Sclerosis. J Mol Neurosci. 2020;70:386-402 pubmed publisher
Lan M, Zhang Y, Wan X, Pan M, Xu Y, Sun S. Melatonin ameliorates ochratoxin A-induced oxidative stress and apoptosis in porcine oocytes. Environ Pollut. 2020;256:113374 pubmed publisher
Munley K, Deyoe J, Ren C, Demas G. Melatonin mediates seasonal transitions in aggressive behavior and circulating androgen profiles in male Siberian hamsters. Horm Behav. 2020;117:104608 pubmed publisher
Portela J, de Winter Korver C, van Daalen S, Meisner A, de Melker A, Repping S, et al. Assessment of fresh and cryopreserved testicular tissues from (pre)pubertal boys during organ culture as a strategy for in vitro spermatogenesis. Hum Reprod. 2019;34:2443-2455 pubmed publisher
Zia S, Berkowitz O, Bedon F, Whelan J, Franks A, Plummer K. Direct comparison of Arabidopsis gene expression reveals different responses to melatonin versus auxin. BMC Plant Biol. 2019;19:567 pubmed publisher
Palmer A, Souza A, Dos Santos V, Cavalheiro J, Schuh F, Zucatto Â, et al. The Effects of Melatonin on the Descending Pain Inhibitory System and Neural Plasticity Markers in Breast Cancer Patients Receiving Chemotherapy: Randomized, Double-Blinded, Placebo-Controlled Trial. Front Pharmacol. 2019;10:1382 pubmed publisher
Liu L, Chen H, Jin J, Tang Z, Yin P, Zhong D, et al. Melatonin ameliorates cerebral ischemia/reperfusion injury through SIRT3 activation. Life Sci. 2019;239:117036 pubmed publisher
Xu G, Zhao J, Liu H, Wang J, Lu W. Melatonin Inhibits Apoptosis and Oxidative Stress of Mouse Leydig Cells via a SIRT1-Dependent Mechanism. Molecules. 2019;24: pubmed publisher
Kim E, Kim G, Taweechaipaisankul A, Lee S, Qasim M, Ahn C, et al. Melatonin enhances porcine embryo development via the Nrf2/ARE signaling pathway. J Mol Endocrinol. 2019;63:175-185 pubmed publisher
Farhood B, Aliasgharzadeh A, Amini P, Rezaeyan A, Tavassoli A, Motevaseli E, et al. Mitigation of Radiation-Induced Lung Pneumonitis and Fibrosis Using Metformin and Melatonin: A Histopathological Study. Medicina (Kaunas). 2019;55: pubmed publisher
Xi Y, Liu M, Xu S, Hong H, Chen M, Tian L, et al. Inhibition of SERPINA3N-dependent neuroinflammation is essential for melatonin to ameliorate trimethyltin chloride-induced neurotoxicity. J Pineal Res. 2019;67:e12596 pubmed publisher
Lee W, Chen L, Lin J, Cheng T, Kuo C, Wu C, et al. Melatonin promotes neuroblastoma cell differentiation by activating hyaluronan synthase 3-induced mitophagy. Cancer Med. 2019;8:4821-4835 pubmed publisher
Chen J, Xia H, Zhang L, Zhang H, Wang D, Tao X. Protective effects of melatonin on sepsis-induced liver injury and dysregulation of gluconeogenesis in rats through activating SIRT1/STAT3 pathway. Biomed Pharmacother. 2019;117:109150 pubmed publisher
Al Dera H, Alassiri M, Eleawa S, Alkhateeb M, Hussein A, Dallak M, et al. Melatonin Improves Memory Deficits in Rats with Cerebral Hypoperfusion, Possibly, Through Decreasing the Expression of Small-Conductance Ca2+-Activated K+ Channels. Neurochem Res. 2019;: pubmed publisher
Zhao Y, Wang H, Chen W, Chen L, Liu D, Wang X, et al. Melatonin attenuates white matter damage after focal brain ischemia in rats by regulating the TLR4/NF-κB pathway. Brain Res Bull. 2019;150:168-178 pubmed publisher
Li Z, Wang Y, Sun N, Liu X, Song E, Zhang Z, et al. Melatonin therapy protects against renal injury before and after release of bilateral ureteral obstruction in rats. Life Sci. 2019;: pubmed publisher
Ding S, Lin N, Sheng X, Zhao Y, Su Y, Xu L, et al. Melatonin stabilizes rupture-prone vulnerable plaques via regulating macrophage polarization in a nuclear circadian receptor RORα-dependent manner. J Pineal Res. 2019;67:e12581 pubmed publisher
Shaw W, Yamauchi H, Mead J, Gowers G, Bell D, Oling D, et al. Engineering a Model Cell for Rational Tuning of GPCR Signaling. Cell. 2019;177:782-796.e27 pubmed publisher
Liu J, Li L, Yan H, Zhang T, Zhang P, Sun Z, et al. Identification of oxidative stress-related Xdh gene as a di(2-ethylhexyl)phthalate (DEHP) target and the use of melatonin to alleviate the DEHP-induced impairments in newborn mouse ovaries. J Pineal Res. 2019;67:e12577 pubmed publisher
Gao T, Wang Z, Dong Y, Cao J, Lin R, Wang X, et al. Role of melatonin in sleep deprivation-induced intestinal barrier dysfunction in mice. J Pineal Res. 2019;67:e12574 pubmed publisher
Baert Y, Dvorakova Hortova K, Margaryan H, Goossens E. Mouse in vitro spermatogenesis on alginate-based 3D bioprinted scaffolds. Biofabrication. 2019;11:035011 pubmed publisher
Zada D, Bronshtein I, Lerer Goldshtein T, Garini Y, Appelbaum L. Sleep increases chromosome dynamics to enable reduction of accumulating DNA damage in single neurons. Nat Commun. 2019;10:895 pubmed publisher
Chen D, Feng Y, Chen L, Liu J, Wang M, Vaziri N, et al. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis. Free Radic Biol Med. 2019;134:484-497 pubmed publisher
Domenech Coca C, Mariné Casadó R, Caimari A, Arola L, Del Bas J, Bladé C, et al. Dual liquid-liquid extraction followed by LC-MS/MS method for the simultaneous quantification of melatonin, cortisol, triiodothyronine, thyroxine and testosterone levels in serum: Applications to a photoperiod study in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2019;1108:11-16 pubmed publisher
Xiao P, Nie J, Wang X, Lu K, Lu S, Liang X. Melatonin alleviates the deterioration of oocytes from mice subjected to repeated superovulation. J Cell Physiol. 2019;234:13413-13422 pubmed publisher
Sun Z, Zhang P, Wang J, Liu J, Li L, Shen W, et al. Melatonin alleviates meiotic defects in fetal mouse oocytes induced by Di (2-ethylhexyl) phthalate in vitro. Aging (Albany NY). 2018;10:4175-4187 pubmed publisher
Khattabi A, Talib W, Alqdeimat D. The effect of polymer length on the in vitro characteristics of a drug loaded and targeted silica nanoparticles. Saudi Pharm J. 2018;26:1022-1026 pubmed publisher
Deshayes N, Genty G, Berthelot F, Paris M. Human long-term deregulated circadian rhythm alters regenerative properties of skin and hair precursor cells. Eur J Dermatol. 2018;28:467-475 pubmed publisher
Fang J, Yan Y, Teng X, Wen X, Li N, Peng S, et al. Melatonin prevents senescence of canine adipose-derived mesenchymal stem cells through activating NRF2 and inhibiting ER stress. Aging (Albany NY). 2018;10:2954-2972 pubmed publisher
Mi Y, Tan D, He Y, Zhou X, Zhou Q, Ji S. Melatonin Modulates lipid Metabolism in HepG2 Cells Cultured in High Concentrations of Oleic Acid: AMPK Pathway Activation may Play an Important Role. Cell Biochem Biophys. 2018;76:463-470 pubmed publisher
Hu X, Li D, Wang J, Guo J, Li Y, Cao Y, et al. Melatonin inhibits endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in lipopolysaccharide-induced endometritis in mice. Int Immunopharmacol. 2018;64:101-109 pubmed publisher
Lin T, Lee J, Kang J, Oqani R, Cho E, Kim S, et al. Melatonin supplementation during prolonged in vitro maturation improves the quality and development of poor-quality porcine oocytes via anti-oxidative and anti-apoptotic effects. Mol Reprod Dev. 2018;85:665-681 pubmed publisher
Kurhaluk N, Szarmach A, Zaitseva O, Sliuta A, Kyriienko S, Winklewski P. Effects of melatonin on low dose lipopolysaccharide-induced oxidative stress in the mouse liver, muscle and kidney. Can J Physiol Pharmacol. 2018;: pubmed publisher
Govender J, Loos B, Marais E, Engelbrecht A. Melatonin improves cardiac and mitochondrial function during doxorubicin-induced cardiotoxicity: A possible role for peroxisome proliferator-activated receptor gamma coactivator 1-alpha and sirtuin activity?. Toxicol Appl Pharmacol. 2018;358:86-101 pubmed publisher
Rastogi S, Haldar C. Comparative effect of melatonin and quercetin in counteracting LPS induced oxidative stress in bone marrow mononuclear cells and spleen of Funambulus pennanti. Food Chem Toxicol. 2018;120:243-252 pubmed publisher
Wang Y, Sun X, Han Z, Li L, Ge W, Zhao Y, et al. Protective effects of melatonin against nicotine-induced disorder of mouse early folliculogenesis. Aging (Albany NY). 2018;10:463-480 pubmed publisher
Maceachern S, Keenan C, Papakonstantinou E, Sharkey K, Patel B. Alterations in melatonin and 5-HT signalling in the colonic mucosa of mice with dextran-sodium sulfate-induced colitis. Br J Pharmacol. 2018;175:1535-1547 pubmed publisher
Reda A, Albalushi H, Montalvo S, Nurmio M, Sahin Z, Hou M, et al. Knock-Out Serum Replacement and Melatonin Effects on Germ Cell Differentiation in Murine Testicular Explant Cultures. Ann Biomed Eng. 2017;45:1783-1794 pubmed publisher
Seltmann S, Trost L, ter Maat A, Gahr M. Natural melatonin fluctuation and its minimally invasive simulation in the zebra finch. Peerj. 2016;4:e1939 pubmed publisher
Oyama T, Nagai R, Fujimoto M, Konishi R, Mita M, Uezono K, et al. Development of a Fully-automated On-line Oxidation Column-switching HPLC System for the Determination of Endogenous Melatonin in Human Clinical Samples. Anal Sci. 2015;31:1129-35 pubmed publisher
Hablitz L, Molzof H, Abrahamsson K, Cooper J, Prosser R, Gamble K. GIRK Channels Mediate the Nonphotic Effects of Exogenous Melatonin. J Neurosci. 2015;35:14957-65 pubmed publisher
Babaee A, Eftekhar Vaghefi S, Asadi Shekaari M, Shahrokhi N, Soltani S, Malekpour Afshar R, et al. Melatonin treatment reduces astrogliosis and apoptosis in rats with traumatic brain injury. Iran J Basic Med Sci. 2015;18:867-72 pubmed
Mukherjee S, Maitra S. Effects of starvation, re-feeding and timing of food supply on daily rhythm features of gut melatonin in carp (Catla catla). Chronobiol Int. 2015;32:1264-77 pubmed publisher
Liu S, Guo Y, Yuan Q, Pan Y, Wang L, Liu Q, et al. Melatonin prevents neural tube defects in the offspring of diabetic pregnancy. J Pineal Res. 2015;59:508-17 pubmed publisher
Li Y, Cassone V. Clock-Controlled Regulation of the Acute Effects of Norepinephrine on Chick Pineal Melatonin Rhythms. J Biol Rhythms. 2015;30:519-32 pubmed publisher
Wang D, Wei Y, Wang T, Wan X, Yang C, Reiter R, et al. Melatonin attenuates (-)-epigallocatehin-3-gallate-triggered hepatotoxicity without compromising its downregulation of hepatic gluconeogenic and lipogenic genes in mice. J Pineal Res. 2015;59:497-507 pubmed publisher
Choopankareh S, Vafaee F, Shafei M, Sadeghnia H, Salarinia R, Zarepoor L, et al. Effects of melatonin and theanine administration on pentylenetetrazole-induced seizures and brain tissue oxidative damage in ovariectomized rats. Turk J Med Sci. 2015;45:842-9 pubmed
Qin F, Zhang J, Zan L, Guo W, Wang J, Chen L, et al. Inhibitory effect of melatonin on testosterone synthesis is mediated via GATA-4/SF-1 transcription factors. Reprod Biomed Online. 2015;31:638-46 pubmed publisher
Solanas E, Sostres C, Serrablo A, Garcia Gil A, Garcia J, Aranguren F, et al. Effect of Dimethyl Sulfoxide and Melatonin on the Isolation of Human Primary Hepatocytes. Cells Tissues Organs. 2015;200:316-25 pubmed publisher
Burke T, Markwald R, McHill A, Chinoy E, Snider J, Bessman S, et al. Effects of caffeine on the human circadian clock in vivo and in vitro. Sci Transl Med. 2015;7:305ra146 pubmed publisher
Manzella N, Bracci M, Strafella E, Staffolani S, Ciarapica V, Copertaro A, et al. Circadian Modulation of 8-Oxoguanine DNA Damage Repair. Sci Rep. 2015;5:13752 pubmed publisher
Byeon Y, Tan D, Reiter R, Back K. Predominance of 2-hydroxymelatonin over melatonin in plants. J Pineal Res. 2015;59:448-54 pubmed publisher
Yip H, Yang C, Chen K, Huang T, Chen Y, Zhen Y, et al. Combined melatonin and exendin-4 therapy preserves renal ultrastructural integrity after ischemia-reperfusion injury in the male rat. J Pineal Res. 2015;59:434-47 pubmed publisher
Yu L, Liang H, Lu Z, Zhao G, Zhai M, Yang Y, et al. Membrane receptor-dependent Notch1/Hes1 activation by melatonin protects against myocardial ischemia-reperfusion injury: in vivo and in vitro studies. J Pineal Res. 2015;59:420-33 pubmed publisher
Charão M, Souto C, Brucker N, Barth A, Jornada D, Fagundez D, et al. Caenorhabditis elegans as an alternative in vivo model to determine oral uptake, nanotoxicity, and efficacy of melatonin-loaded lipid-core nanocapsules on paraquat damage. Int J Nanomedicine. 2015;10:5093-106 pubmed publisher
Gobbo M, Dizeyi N, Abrahamsson P, Bertilsson P, Masitéli V, Pytlowanciv E, et al. Influence of Melatonin on the Proliferative and Apoptotic Responses of the Prostate under Normal and Hyperglycemic Conditions. J Diabetes Res. 2015;2015:538529 pubmed publisher
Su L, Li H, Lv L, Feng Y, Li G, Luo R, et al. Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation. Autophagy. 2015;11:1745-59 pubmed publisher
Quartararo C, Reznik E, deCarvalho A, Mikkelsen T, Stockwell B. High-Throughput Screening of Patient-Derived Cultures Reveals Potential for Precision Medicine in Glioblastoma. ACS Med Chem Lett. 2015;6:948-52 pubmed publisher
Elbe H, Esrefoglu M, Vardi N, Taslidere E, Ozerol E, Tanbek K. Melatonin, quercetin and resveratrol attenuates oxidative hepatocellular injury in streptozotocin-induced diabetic rats. Hum Exp Toxicol. 2015;34:859-68 pubmed publisher
Wongprayoon P, Govitrapong P. Melatonin attenuates methamphetamine-induced neuroinflammation through the melatonin receptor in the SH-SY5Y cell line. Neurotoxicology. 2015;50:122-30 pubmed publisher
Pablos P, Mendiguren A, Pineda J. Contribution of nitric oxide-dependent guanylate cyclase and reactive oxygen species signaling pathways to desensitization of μ-opioid receptors in the rat locus coeruleus. Neuropharmacology. 2015;99:422-31 pubmed publisher
Khan S, Shaeib F, Najafi T, Kavdia M, Gonik B, Saed G, et al. Diffused Intra-Oocyte Hydrogen Peroxide Activates Myeloperoxidase and Deteriorates Oocyte Quality. PLoS ONE. 2015;10:e0132388 pubmed publisher
Wu L, Acebo C, Seifer R, Carskadon M. Sleepiness and Cognitive Performance among Younger and Older Adolescents across a 28-Hour Forced Desynchrony Protocol. Sleep. 2015;38:1965-72 pubmed publisher
Kepka M, Szwejser E, Pijanowski L, Verburg van Kemenade B, Chadzinska M. A role for melatonin in maintaining the pro- and anti-inflammatory balance by influencing leukocyte migration and apoptosis in carp. Dev Comp Immunol. 2015;53:179-90 pubmed publisher
Pan X, Zhu L, Lu H, Wang D, Lu Q, Yan H. Melatonin Attenuates Oxidative Damage Induced by Acrylamide In Vitro and In Vivo. Oxid Med Cell Longev. 2015;2015:703709 pubmed publisher
Oh B, Lee C. Development of Man-rGO for Targeted Eradication of Macrophage Ablation. Mol Pharm. 2015;12:3226-36 pubmed publisher
O Neal Moffitt G, Delić V, Bradshaw P, Olcese J. Prophylactic melatonin significantly reduces Alzheimer's neuropathology and associated cognitive deficits independent of antioxidant pathways in AβPP(swe)/PS1 mice. Mol Neurodegener. 2015;10:27 pubmed publisher
Foster B, Cvijovic K, Boon H, Tam T, Liu R, Murty M, et al. Melatonin Interaction Resulting in Severe Sedation. J Pharm Pharm Sci. 2015;18:124-31 pubmed
Johansson M, Agusti A, Llansola M, Montoliu C, Strömberg J, Malinina E, et al. GR3027 antagonizes GABAA receptor-potentiating neurosteroids and restores spatial learning and motor coordination in rats with chronic hyperammonemia and hepatic encephalopathy. Am J Physiol Gastrointest Liver Physiol. 2015;309:G400-9 pubmed publisher
Zhao H, Su T, Huo L, Wei H, Jiang Y, Xu L, et al. Unveiling the mechanism of melatonin impacts on maize seedling growth: sugar metabolism as a case. J Pineal Res. 2015;59:255-66 pubmed publisher
Pi H, Xu S, Reiter R, Guo P, Zhang L, Li Y, et al. SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin. Autophagy. 2015;11:1037-51 pubmed publisher
Chen Y, Qing W, Sun M, Lv L, Guo D, Jiang Y. Melatonin protects hepatocytes against bile acid-induced mitochondrial oxidative stress via the AMPK-SIRT3-SOD2 pathway. Free Radic Res. 2015;49:1275-84 pubmed publisher
Wang Y, Qiu J, Zhu W, Wang X, Zhang P, Wang D, et al. Enantioselective Metabolism and Interference on Tryptophan Metabolism of Myclobutanil in Rat Hepatocytes. Chirality. 2015;27:643-9 pubmed publisher
Hernández I, Gomez F, Cerutti S, Arana M, Silva M. Melatonin in Arabidopsis thaliana acts as plant growth regulator at low concentrations and preserves seed viability at high concentrations. Plant Physiol Biochem. 2015;94:191-6 pubmed publisher
Gim S, Koh P. Melatonin attenuates hepatic ischemia through mitogen-activated protein kinase signaling. J Surg Res. 2015;198:228-36 pubmed publisher
Zhao L, An R, Yang Y, Yang X, Liu H, Yue L, et al. Melatonin alleviates brain injury in mice subjected to cecal ligation and puncture via attenuating inflammation, apoptosis, and oxidative stress: the role of SIRT1 signaling. J Pineal Res. 2015;59:230-9 pubmed publisher
Quan X, Wang J, Liang C, Zheng H, Zhang L. Melatonin inhibits tunicamycin-induced endoplasmic reticulum stress and insulin resistance in skeletal muscle cells. Biochem Biophys Res Commun. 2015;463:1102-7 pubmed publisher
Charão M, Baierle M, Gauer B, Göethel G, Fracasso R, Paese K, et al. Protective effects of melatonin-loaded lipid-core nanocapsules on paraquat-induced cytotoxicity and genotoxicity in a pulmonary cell line. Mutat Res Genet Toxicol Environ Mutagen. 2015;784-785:1-9 pubmed publisher
Butler M, Smales C, Wu H, Hussain M, Mohamed Y, Morimoto M, et al. The Circadian System Contributes to Apnea Lengthening across the Night in Obstructive Sleep Apnea. Sleep. 2015;38:1793-801 pubmed publisher
Ranieri D, Avitabile D, Shiota M, Yokomizo A, Naito S, Bizzarri M, et al. Nuclear redox imbalance affects circadian oscillation in HaCaT keratinocytes. Int J Biochem Cell Biol. 2015;65:113-24 pubmed publisher
Loureiro R, Magalhães Novais S, Mesquita K, Baldeiras I, Sousa I, Tavares L, et al. Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells. Oncotarget. 2015;6:17081-96 pubmed
Guo Q, Dong Y, Cao J, Wang Z, Zhang Z, Chen Y. Developmental changes of melatonin receptor expression in the spleen of the chicken, Gallus domesticus. Acta Histochem. 2015;117:559-65 pubmed publisher
Feng N, Fergus D, Bass A. Neural transcriptome reveals molecular mechanisms for temporal control of vocalization across multiple timescales. BMC Genomics. 2015;16:408 pubmed publisher
Vengeliene V, Noori H, Spanagel R. Activation of Melatonin Receptors Reduces Relapse-Like Alcohol Consumption. Neuropsychopharmacology. 2015;40:2897-906 pubmed publisher
Schmid T, Snoek L, Fröhli E, van der Bent M, Kammenga J, Hajnal A. Systemic Regulation of RAS/MAPK Signaling by the Serotonin Metabolite 5-HIAA. PLoS Genet. 2015;11:e1005236 pubmed publisher
Zhou L, Chen X, Liu T, Gong Y, Chen S, Pan G, et al. Melatonin reverses H2 O2 -induced premature senescence in mesenchymal stem cells via the SIRT1-dependent pathway. J Pineal Res. 2015;59:190-205 pubmed publisher
Ordoñez R, Fernandez A, Prieto Domínguez N, Martinez L, Garcia Ruiz C, Fernandez Checa J, et al. Ceramide metabolism regulates autophagy and apoptotic cell death induced by melatonin in liver cancer cells. J Pineal Res. 2015;59:178-89 pubmed publisher
Howard C, Lutterschmidt D. The Effects of Melatonin on Brain Arginine Vasotocin: Relationship with Sex and Seasonal Differences in Melatonin Receptor Type 1 in Green Treefrogs (Hyla cinerea). J Neuroendocrinol. 2015;27:670-9 pubmed publisher
Lapshina E, Zamaraeva M, Cheshchevik V, Olchowik Grabarek E, Sekowski S, Zukowska I, et al. Cranberry flavonoids prevent toxic rat liver mitochondrial damage in vivo and scavenge free radicals in vitro. Cell Biochem Funct. 2015;33:202-10 pubmed publisher
Shi H, Chen Y, Tan D, Reiter R, Chan Z, He C. Melatonin induces nitric oxide and the potential mechanisms relate to innate immunity against bacterial pathogen infection in Arabidopsis. J Pineal Res. 2015;59:102-8 pubmed publisher
San Miguel B, Crespo I, Sánchez D, González Fernández B, Ortiz de Urbina J, Tunon M, et al. Melatonin inhibits autophagy and endoplasmic reticulum stress in mice with carbon tetrachloride-induced fibrosis. J Pineal Res. 2015;59:151-62 pubmed publisher
Shi H, Wang X, Tan D, Reiter R, Chan Z. Comparative physiological and proteomic analyses reveal the actions of melatonin in the reduction of oxidative stress in Bermuda grass (Cynodon dactylon (L). Pers.). J Pineal Res. 2015;59:120-31 pubmed publisher
Goyal A, Terry P, Superak H, Nell Dybdahl C, Chowdhury R, Phillips L, et al. Melatonin supplementation to treat the metabolic syndrome: a randomized controlled trial. Diabetol Metab Syndr. 2014;6:124 pubmed publisher
Ni H, Sun Q, Tian T, Feng X, Sun B. Long-term expression of metabolism-associated genes in the rat hippocampus following recurrent neonatal seizures and its regulation by melatonin. Mol Med Rep. 2015;12:2727-34 pubmed publisher
Yanilmaz M, Akduman D, Sagun O, Haksever M, Yazicilar O, Orhan I, et al. The effects of aminoguanidine, methylprednisolone, and melatonin on nerve recovery in peripheral facial nerve neurorrhaphy. J Craniofac Surg. 2015;26:667-72 pubmed publisher
Arbon E, Knurowska M, Dijk D. Randomised clinical trial of the effects of prolonged-release melatonin, temazepam and zolpidem on slow-wave activity during sleep in healthy people. J Psychopharmacol. 2015;29:764-76 pubmed publisher
Talib W, Saleh S. Propionibacterium acnes Augments Antitumor, Anti-Angiogenesis and Immunomodulatory Effects of Melatonin on Breast Cancer Implanted in Mice. PLoS ONE. 2015;10:e0124384 pubmed publisher
Liang C, Zheng G, Li W, Wang Y, Hu B, Wang H, et al. Melatonin delays leaf senescence and enhances salt stress tolerance in rice. J Pineal Res. 2015;59:91-101 pubmed publisher
Thakor A, Allison B, Niu Y, Botting K, Seron Ferre M, Herrera E, et al. Melatonin modulates the fetal cardiovascular defense response to acute hypoxia. J Pineal Res. 2015;59:80-90 pubmed publisher
Swanson G, Gorenz A, Shaikh M, Desai V, Forsyth C, Fogg L, et al. Decreased melatonin secretion is associated with increased intestinal permeability and marker of endotoxemia in alcoholics. Am J Physiol Gastrointest Liver Physiol. 2015;308:G1004-11 pubmed publisher
Zhao J, Young Y, Fradette J, Eliopoulos N. Melatonin pretreatment of human adipose tissue-derived mesenchymal stromal cells enhances their prosurvival and protective effects on human kidney cells. Am J Physiol Renal Physiol. 2015;308:F1474-83 pubmed publisher
Obayashi K, Saeki K, Kurumatani N. Independent Associations Between Nocturia and Nighttime Blood Pressure/Dipping in Elderly Individuals: The HEIJO-KYO Cohort. J Am Geriatr Soc. 2015;63:733-8 pubmed publisher
Al Olayan E, El Khadragy M, Abdel Moneim A. The protective properties of melatonin against aluminium-induced neuronal injury. Int J Exp Pathol. 2015;96:196-202 pubmed publisher
Hara T, Otsuka F, Tsukamoto Yamauchi N, Inagaki K, Hosoya T, Nakamura E, et al. Mutual effects of melatonin and activin on induction of aldosterone production by human adrenocortical cells. J Steroid Biochem Mol Biol. 2015;152:8-15 pubmed publisher
Xu C, Wang Z, Huang X, Dai L, Cao C, Li Z. Involvement of ROS-alpha v beta 3 integrin-FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia. J Transl Med. 2015;13:95 pubmed publisher
Wang S, Zhai X, Li S, McCabe M, Wang X, Rong P. Transcutaneous vagus nerve stimulation induces tidal melatonin secretion and has an antidiabetic effect in Zucker fatty rats. PLoS ONE. 2015;10:e0124195 pubmed publisher
Bułdak R, Pilc Gumuła K, Bułdak Ł, Witkowska D, Kukla M, Polaniak R, et al. Effects of ghrelin, leptin and melatonin on the levels of reactive oxygen species, antioxidant enzyme activity and viability of the HCT 116 human colorectal carcinoma cell line. Mol Med Rep. 2015;12:2275-82 pubmed publisher
Lorente L, Martín M, Abreu González P, de la Cruz T, Ferreres J, Solé Violán J, et al. Serum melatonin levels are associated with mortality in severe septic patients. J Crit Care. 2015;30:860.e1-6 pubmed publisher
Liu X, Zi Y, Liu Y, Zhang Y, Xiang L, Hou M. Melatonin exerts protective effect on N2a cells under hypoxia conditions through Zip1/ERK pathway. Neurosci Lett. 2015;595:74-80 pubmed publisher
Wang Y, Zhu W, Qiu J, Wang X, Zhang P, Yan J, et al. Monitoring tryptophan metabolism after exposure to hexaconazole and the enantioselective metabolism of hexaconazole in rat hepatocytes in vitro. J Hazard Mater. 2015;295:9-16 pubmed publisher
Jain S, Horn P, Simakajornboon N, Beebe D, Holland K, Byars A, et al. Melatonin improves sleep in children with epilepsy: a randomized, double-blind, crossover study. Sleep Med. 2015;16:637-44 pubmed publisher
Ali T, Kim M. Melatonin ameliorates amyloid beta-induced memory deficits, tau hyperphosphorylation and neurodegeneration via PI3/Akt/GSk3? pathway in the mouse hippocampus. J Pineal Res. 2015;59:47-59 pubmed publisher
Xiang S, Dauchy R, Hauch A, Mao L, Yuan L, Wren M, et al. Doxorubicin resistance in breast cancer is driven by light at night-induced disruption of the circadian melatonin signal. J Pineal Res. 2015;59:60-9 pubmed publisher
Soliman A, Lacasse A, Lanoix D, Sagrillo Fagundes L, Boulard V, Vaillancourt C. Placental melatonin system is present throughout pregnancy and regulates villous trophoblast differentiation. J Pineal Res. 2015;59:38-46 pubmed publisher
Ni H, Sun Q, Tian T, Feng X, Sun B. Prophylactic treatment with melatonin before recurrent neonatal seizures: Effects on long-term neurobehavioral changes and the underlying expression of metabolism-related genes in rat hippocampus and cerebral cortex. Pharmacol Biochem Behav. 2015;133:25-30 pubmed publisher
Natarajan N, Ramakrishnan P, Lakshmanan V, Palakodeti D, Rangiah K. A quantitative metabolomics peek into planarian regeneration. Analyst. 2015;140:3445-64 pubmed publisher
Jeong J, Park S. Melatonin regulates the autophagic flux via activation of alpha-7 nicotinic acetylcholine receptors. J Pineal Res. 2015;59:24-37 pubmed publisher
Costa L, Pellacani C, Dao K, Kavanagh T, Roqué P. The brominated flame retardant BDE-47 causes oxidative stress and apoptotic cell death in vitro and in vivo in mice. Neurotoxicology. 2015;48:68-76 pubmed publisher
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product information
Catalog Number :
M5250
Product Name :
Melatonin
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
powder, ≥98% (TLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA