product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-MDM2 antibody produced in mouse
catalog :
M4308
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SMP14
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation
more info or order :
citations: 23
Published Application/Species/Sample/Dilution | Reference |
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Hamilton G, Abraham A, Morton J, Sampson O, Pefani D, Khoronenkova S, et al. AKT regulates NPM dependent ARF localization and p53mut stability in tumors. Oncotarget. 2014;5:6142-67 pubmed
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Gonon G, Groetz J, De Toledo S, Howell R, Fromm M, Azzam E. Nontargeted stressful effects in normal human fibroblast cultures exposed to low fluences of high charge, high energy (HZE) particles: kinetics of biologic responses and significance of secondary radiations. Radiat Res. 2013;179:444-57 pubmed publisher
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Shiraishi T, Nielsen P. Down-regulation of MDM2 and activation of p53 in human cancer cells by antisense 9-aminoacridine-PNA (peptide nucleic acid) conjugates. Nucleic Acids Res. 2004;32:4893-902 pubmed
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Fujioka S, Schmidt C, Sclabas G, Li Z, Pelicano H, Peng B, et al. Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB. J Biol Chem. 2004;279:27549-59 pubmed
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Picksley S, Vojtesek B, Sparks A, Lane D. Immunochemical analysis of the interaction of p53 with MDM2;--fine mapping of the MDM2 binding site on p53 using synthetic peptides. Oncogene. 1994;9:2523-9 pubmed
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Hickman E, Picksley S, Vousden K. Cells expressing HPV16 E7 continue cell cycle progression following DNA damage induced p53 activation. Oncogene. 1994;9:2177-81 pubmed
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Martin K, Trouche D, Hagemeier C, Sørensen T, La Thangue N, Kouzarides T. Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein. Nature. 1995;375:691-4 pubmed
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product information
Product No. :
M4308
Product Name :
Monoclonal Anti-MDM2 antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
SMP14
Applications/Description :
Suitable for immunocytochemistry; western blot: 1:1,000 using a whole extract of transfected 293T (human embryonal kidney) cells expressing human MDM2; microarray; indirect ELISA; immunoprecipitation (IP); immunohistochemistry (froze
Species Reactivity :
rat, human, mouse (weak)
Isotype :
IgG1
Storage :
Store at -20°C
more info or order :
company information

MilliporeSigma
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