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product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
3-Methoxytyramine hydrochloride
catalog :
M4251
citations: 35
Reference
Lim H, Vo M, Kim D, Lee U, Yoon J, Kim H, et al. DRG2 Deficient Mice Exhibit Impaired Motor Behaviors with Reduced Striatal Dopamine Release. Int J Mol Sci. 2019;21: pubmed publisher
Chen H, Nwe P, Yang Y, Rosen C, Bielecka A, Kuchroo M, et al. A Forward Chemical Genetic Screen Reveals Gut Microbiota Metabolites That Modulate Host Physiology. Cell. 2019;177:1217-1231.e18 pubmed publisher
Verly I, Leen R, Meinsma J, Hooijer G, Savci Heijink C, van Nes J, et al. Catecholamine excretion profiles identify clinical subgroups of neuroblastoma patients. Eur J Cancer. 2019;111:21-29 pubmed publisher
Qin Q, Li H, Shi X, Xu G. Facile synthesis of Fe₃O₄@polyethyleneimine modified with 4-formylphenylboronic acid for the highly selective extraction of major catecholamines from human urine. J Sep Sci. 2015;38:2857-64 pubmed publisher
Ichinose T, Moriyasu K, Nakahata A, Tanaka M, Matsui T, Furuya S. Orally administrated dipeptide Ser-Tyr efficiently stimulates noradrenergic turnover in the mouse brain. Biosci Biotechnol Biochem. 2015;79:1542-7 pubmed publisher
Saylor R, Reid E, Lunte S. Microchip electrophoresis with electrochemical detection for the determination of analytes in the dopamine metabolic pathway. Electrophoresis. 2015;36:1912-9 pubmed publisher
Tufi S, Lamoree M, de Boer J, Leonards P. Simultaneous analysis of multiple neurotransmitters by hydrophilic interaction liquid chromatography coupled to tandem mass spectrometry. J Chromatogr A. 2015;1395:79-87 pubmed publisher
Możdżeń E, Kajta M, Wąsik A, Lenda T, Antkiewicz Michaluk L. Salsolinol, an endogenous compound triggers a two-phase opposing action in the central nervous system. Neurotox Res. 2015;27:300-13 pubmed publisher
Eisenhofer G, Peitzsch M. Laboratory evaluation of pheochromocytoma and paraganglioma. Clin Chem. 2014;60:1486-99 pubmed publisher
van Duinen N, Corssmit E, de Jong W, Brookman D, Kema I, Romijn J. Plasma levels of free metanephrines and 3-methoxytyramine indicate a higher number of biochemically active HNPGL than 24-h urinary excretion rates of catecholamines and metabolites. Eur J Endocrinol. 2013;169:377-82 pubmed publisher
Peitzsch M, Prejbisz A, Kroiß M, Beuschlein F, Arlt W, Januszewicz A, et al. Analysis of plasma 3-methoxytyramine, normetanephrine and metanephrine by ultraperformance liquid chromatography-tandem mass spectrometry: utility for diagnosis of dopamine-producing metastatic phaeochromocytoma. Ann Clin Biochem. 2013;50:147-55 pubmed publisher
Park J, Myung S, Kim I, Choi D, Kwon S, Yoon S. Simultaneous measurement of serotonin, dopamine and their metabolites in mouse brain extracts by high-performance liquid chromatography with mass spectrometry following derivatization with ethyl chloroformate. Biol Pharm Bull. 2013;36:252-8 pubmed
Wąsik A, Romańska I, Michaluk J, Antkiewicz Michaluk L. Comparative behavioral and neurochemical studies of R- and S-1-methyl-1,2,3,4-tetrahydroisoquinoline stereoisomers in the rat. Pharmacol Rep. 2012;64:857-69 pubmed
Twentyman J, Cradic K, Singh R, Grebe S. Ionic cross talk can lead to overestimation of 3-methoxytyramine during quantification of metanephrines by mass spectrometry. Clin Chem. 2012;58:1156-8 pubmed publisher
Pettersson F, Svensson P, Waters S, Waters N, Sonesson C. Synthesis and evaluation of a set of para-substituted 4-phenylpiperidines and 4-phenylpiperazines as monoamine oxidase (MAO) inhibitors. J Med Chem. 2012;55:3242-9 pubmed publisher
Eisenhofer G, Lenders J, Siegert G, Bornstein S, Friberg P, Milosevic D, et al. Plasma methoxytyramine: a novel biomarker of metastatic pheochromocytoma and paraganglioma in relation to established risk factors of tumour size, location and SDHB mutation status. Eur J Cancer. 2012;48:1739-49 pubmed publisher
Le Jacques A, Abalain J, Le Saos F, Carre J. [Significance of 3-methoxytyramine urine measurement in the diagnosis of pheochromocytomas and paragangliomas: about 28 patients]. Ann Biol Clin (Paris). 2011;69:555-9 pubmed publisher
Claude B, Nehmé R, Morin P. Analysis of urinary neurotransmitters by capillary electrophoresis: sensitivity enhancement using field-amplified sample injection and molecular imprinted polymer solid phase extraction. Anal Chim Acta. 2011;699:242-8 pubmed publisher
Wasik A, Romańska I, Antkiewicz Michaluk L. Important role of 3-methoxytyramine in the inhibition of cocaine sensitization by 1-methyl-1,2,3,4-tetrahydroisoquinoline: an in vivo microdialysis study. Pharmacol Rep. 2010;62:983-97 pubmed
Eisenhofer G, Lenders J, Timmers H, Mannelli M, Grebe S, Hofbauer L, et al. Measurements of plasma methoxytyramine, normetanephrine, and metanephrine as discriminators of different hereditary forms of pheochromocytoma. Clin Chem. 2011;57:411-20 pubmed publisher
van der Horst Schrivers A, Osinga T, Kema I, van der Laan B, Dullaart R. Dopamine excess in patients with head and neck paragangliomas. Anticancer Res. 2010;30:5153-8 pubmed
Sotnikova T, Beaulieu J, Espinoza S, Masri B, Zhang X, Salahpour A, et al. The dopamine metabolite 3-methoxytyramine is a neuromodulator. PLoS ONE. 2010;5:e13452 pubmed publisher
Muthian G, Mackey V, King J, Charlton C. Modeling a sensitization stage and a precipitation stage for Parkinson's disease using prenatal and postnatal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration. Neuroscience. 2010;169:1085-93 pubmed publisher
Vonaparti A, Lyris E, Panderi I, Koupparis M, Georgakopoulos C. Direct injection horse-urine analysis for the quantification and confirmation of threshold substances for doping control. IV. Determination of 3-methoxytyramine by hydrophilic interaction liquid chromatography/quadrupole time-of-flight mass spectrome. Drug Test Anal. 2009;1:365-71 pubmed publisher
Alachkar A, Brotchie J, Jones O. Binding of dopamine and 3-methoxytyramine as l-DOPA metabolites to human alpha(2)-adrenergic and dopaminergic receptors. Neurosci Res. 2010;67:245-9 pubmed publisher
Pillai D, Callen S. Pilot quality assurance programme for plasma metanephrines. Ann Clin Biochem. 2010;47:137-42 pubmed publisher
van Duinen N, Steenvoorden D, Kema I, Jansen J, Vriends A, Bayley J, et al. Increased urinary excretion of 3-methoxytyramine in patients with head and neck paragangliomas. J Clin Endocrinol Metab. 2010;95:209-14 pubmed publisher
de Jong W, Eisenhofer G, Post W, Muskiet F, de Vries E, Kema I. Dietary influences on plasma and urinary metanephrines: implications for diagnosis of catecholamine-producing tumors. J Clin Endocrinol Metab. 2009;94:2841-9 pubmed publisher
Sasaki T, Fukushima T, Yamashita K, Toyo oka T. Stereoselective effect of kynurenine enantiomers on the excretion of serotonin and its metabolite in rat urine. Chirality. 2010;22:258-61 pubmed publisher
Viaggi C, Vaglini F, Pardini C, Caramelli A, Corsini G. MPTP-induced model of Parkinson's disease in cytochrome P450 2E1 knockout mice. Neuropharmacology. 2009;56:1075-81 pubmed publisher
Morissette M, Di Paolo T. Effect of estradiol on striatal dopamine activity of female hemiparkinsonian monkeys. J Neurosci Res. 2009;87:1634-44 pubmed publisher
Antkiewicz Michaluk L, Ossowska K, Romańska I, Michaluk J, Vetulani J. 3-Methoxytyramine, an extraneuronal dopamine metabolite plays a physiological role in the brain as an inhibitory regulator of catecholaminergic activity. Eur J Pharmacol. 2008;599:32-5 pubmed publisher
Damasceno Oliveira A, Fernández Durán B, Gonçalves J, Serrao P, Soares da Silva P, Reis Henriques M, et al. Effects of cyclic hydrostatic pressure on the brain biogenic amines concentrations in the flounder, Platichthys flesus. Gen Comp Endocrinol. 2007;153:385-9 pubmed
Jung M, Munro N, Shi G, Michael A, Weber S. Use of tris(2,2'-bipyridine)osmium as a photoluminescence-following electron-transfer reagent for postcolumn detection in capillary high-performance liquid chromatography. Anal Chem. 2006;78:1761-8 pubmed
Klejbor I, Myers J, Hausknecht K, Corso T, Gambino A, Morys J, et al. Fibroblast growth factor receptor signaling affects development and function of dopamine neurons - inhibition results in a schizophrenia-like syndrome in transgenic mice. J Neurochem. 2006;97:1243-58 pubmed
product information
Catalog Number :
M4251
Product Name :
3-Methoxytyramine hydrochloride
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥95.5%, crystalline
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA