Reference |
---|
Cutler M, Lowthers E, Richard C, Hajducek D, Spagnuolo P, Blay J. Chemotherapeutic agents attenuate CXCL12-mediated migration of colon cancer cells by selecting for CXCR4-negative cells and increasing peptidase CD26. BMC Cancer. 2015;15:882 pubmed publisher
|
Tanimoto A, Shinozaki Y, Nozawa K, Kimoto Y, Amano W, Matsuo A, et al. Improvement of spontaneous locomotor activity with JAK inhibition by JTE-052 in rat adjuvant-induced arthritis. BMC Musculoskelet Disord. 2015;16:339 pubmed publisher
|
Zheng H, Tai C, Su J, Zou X, Gao F. Ultra-small mesoporous silica nanoparticles as efficient carriers for pH responsive releases of anti-cancer drugs. Dalton Trans. 2015;44:20186-92 pubmed publisher
|
Sevelda F, Mayr L, Kubista B, Lötsch D, Van Schoonhoven S, Windhager R, et al. EGFR is not a major driver for osteosarcoma cell growth in vitro but contributes to starvation and chemotherapy resistance. J Exp Clin Cancer Res. 2015;34:134 pubmed publisher
|
Deisting W, Raum T, Kufer P, Baeuerle P, Münz M. Impact of Diverse Immune Evasion Mechanisms of Cancer Cells on T Cells Engaged by EpCAM/CD3-Bispecific Antibody Construct AMG 110. PLoS ONE. 2015;10:e0141669 pubmed publisher
|
Figueiró F, de Oliveira C, Rockenbach L, Mendes F, Bergamin L, Jandrey E, et al. Pharmacological Improvement and Preclinical Evaluation of Methotrexate-Loaded Lipid-Core Nanocapsules in a Glioblastoma Model. J Biomed Nanotechnol. 2015;11:1808-18 pubmed
|
Oktaria S, Corde S, Lerch M, Konstantinov K, Rosenfeld A, Tehei M. Indirect radio-chemo-beta therapy: a targeted approach to increase biological efficiency of x-rays based on energy. Phys Med Biol. 2015;60:7847-59 pubmed publisher
|
Perez Aso M, Montesinos M, Mediero A, Wilder T, Schafer P, Cronstein B. Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors. Arthritis Res Ther. 2015;17:249 pubmed publisher
|
Liu Y, Cui Y, Chen Y, Gao X, Su Y, Cui L. Effects of dexamethasone, celecoxib, and methotrexate on the histology and metabolism of bone tissue in healthy Sprague Dawley rats. Clin Interv Aging. 2015;10:1245-53 pubmed publisher
|
Klećkowska Nawrot J, Chęć A, Goździewska Harłajczuk K, Nowaczyk R, Barszcz K. Light and electron microscopic studies of the Harderian gland in Bilgorajska goose (Anser anser). Acta Biol Hung. 2015;66:249-57 pubmed publisher
|
Godley B, Kraft E, Giannos S, Zhao Z, Haag A, Wen J. Photokinetic Drug Delivery: Light-Enhanced Permeation in an In Vitro Eye Model. J Ocul Pharmacol Ther. 2015;31:650-7 pubmed publisher
|
Vermaak E, Tansley S, McHugh N. The evidence for immunotherapy in dermatomyositis and polymyositis: a systematic review. Clin Rheumatol. 2015;34:2089-95 pubmed publisher
|
Quartararo C, Reznik E, deCarvalho A, Mikkelsen T, Stockwell B. High-Throughput Screening of Patient-Derived Cultures Reveals Potential for Precision Medicine in Glioblastoma. ACS Med Chem Lett. 2015;6:948-52 pubmed publisher
|
Wei Y, Sun X, Hua M, Tan W, Wang F, Zhang M. Inhibitory Effect of a Novel Antirheumatic Drug T-614 on the IL-6-Induced RANKL/OPG, IL-17, and MMP-3 Expression in Synovial Fibroblasts from Rheumatoid Arthritis Patients. Biomed Res Int. 2015;2015:214683 pubmed publisher
|
Shaul P, Steinbuch K, Blacher E, Stein R, Fridman M. Exploring the Effects of Glycosylation and Etherification of the Side Chains of the Anticancer Drug Mitoxantrone. ChemMedChem. 2015;10:1528-38 pubmed publisher
|
Maher H, Ragab M, El Kimary E. Chemometrics-assisted Spectrofluorimetric Determination of Two Co-administered Drugs of Major Interaction, Methotrexate and Aspirin, in Human Urine Following Acid-induced Hydrolysis. Comb Chem High Throughput Screen. 2015;18:723-34 pubmed
|
Nakamura H, Yamashita N, Kanamaru Y, Tachibana T, Sekino Y, Chen S, et al. Quantitative analysis of intraneuronal transport in human iPS neurons. J Pharmacol Sci. 2015;128:170-8 pubmed publisher
|
Gómez A, MartÃnez C, González M, Luque A, Melen G, MartÃnez J, et al. Chemokines and relapses in childhood acute lymphoblastic leukemia: A role in migration and in resistance to antileukemic drugs. Blood Cells Mol Dis. 2015;55:220-7 pubmed publisher
|
Park J, Jang J, Choi J, Kang M, Woo Y, Seong Y, et al. DC-Based Immunotherapy Combined with Low-Dose Methotrexate Effective in the Treatment of Advanced CIA in Mice. J Immunol Res. 2015;2015:834085 pubmed publisher
|
Tag H. Hepatoprotective effect of mulberry (Morus nigra) leaves extract against methotrexate induced hepatotoxicity in male albino rat. BMC Complement Altern Med. 2015;15:252 pubmed publisher
|
Zhao N, Pei S, Qi J, Zeng Z, Iyer S, Lin P, et al. Oligonucleotide aptamer-drug conjugates for targeted therapy of acute myeloid leukemia. Biomaterials. 2015;67:42-51 pubmed publisher
|
Ferreira M, Chaves L, Lima S, Reis S. Optimization of nanostructured lipid carriers loaded with methotrexate: A tool for inflammatory and cancer therapy. Int J Pharm. 2015;492:65-72 pubmed publisher
|
Oyen D, Fenwick R, Stanfield R, Dyson H, Wright P. Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway. J Am Chem Soc. 2015;137:9459-68 pubmed publisher
|
Wahl S, Kennedy A, Wyatt B, Moore A, Pridgen D, Cherry A, et al. The role of folate metabolism in orofacial development and clefting. Dev Biol. 2015;405:108-22 pubmed publisher
|
Jeronimo M, Colombo M, Astrakianakis G, Hon C. A surface wipe sampling and LC-MS/MS method for the simultaneous detection of six antineoplastic drugs commonly handled by healthcare workers. Anal Bioanal Chem. 2015;407:7083-92 pubmed publisher
|
Thomas S, Fisher K, Snowden J, Danson S, Brown S, Zeidler M. Methotrexate Is a JAK/STAT Pathway Inhibitor. PLoS ONE. 2015;10:e0130078 pubmed publisher
|
de Thurah A, Nørgaard M, Stengaard Pedersen K. Methotrexate utilization in Rheumatoid arthritis. A register-based cohort-study of treatment re-starts after gabs of at least 90 days. Springerplus. 2015;4:227 pubmed publisher
|
Liu Y, Zhou S, Nissel J, Wu A, Lau H, Palmisano M. The pharmacokinetic effect of coadministration of apremilast and methotrexate in individuals with rheumatoid arthritis and psoriatic arthritis. Clin Pharmacol Drug Dev. 2014;3:456-465 pubmed
|
El Sheikh A, Morsy M, Abdalla A, Hamouda A, Alhaider I. Mechanisms of Thymoquinone Hepatorenal Protection in Methotrexate-Induced Toxicity in Rats. Mediators Inflamm. 2015;2015:859383 pubmed publisher
|
Loubet P, Kernéis S, Groh M, Loulergue P, Blanche P, Verger P, et al. Attitude, knowledge and factors associated with influenza and pneumococcal vaccine uptake in a large cohort of patients with secondary immune deficiency. Vaccine. 2015;33:3703-8 pubmed publisher
|
Mori F, Sacconi A, Canu V, Ganci F, Novello M, Anelli V, et al. miR-181c associates with tumor relapse of high grade osteosarcoma. Oncotarget. 2015;6:13946-61 pubmed
|
Ranninger C, Rurik M, Limonciel A, Ruzek S, Reischl R, Wilmes A, et al. Nephron Toxicity Profiling via Untargeted Metabolome Analysis Employing a High Performance Liquid Chromatography-Mass Spectrometry-based Experimental and Computational Pipeline. J Biol Chem. 2015;290:19121-32 pubmed publisher
|
Vallo S, Michaelis M, Rothweiler F, Bartsch G, Gust K, Limbart D, et al. Drug-Resistant Urothelial Cancer Cell Lines Display Diverse Sensitivity Profiles to Potential Second-Line Therapeutics. Transl Oncol. 2015;8:210-6 pubmed publisher
|
Chernobrovkin A, Marin Vicente C, Visa N, Zubarev R. Functional Identification of Target by Expression Proteomics (FITExP) reveals protein targets and highlights mechanisms of action of small molecule drugs. Sci Rep. 2015;5:11176 pubmed publisher
|
Klećkowska Nawrot J, Nowaczyk R, Goździewska Harłajczuk K, Krasucki K, Janeczek M. Histological, histochemical and fine structure studies of the lacrimal gland and superficial gland of the third eyelid and their significance on the proper function of the eyeball in alpaca (Vicugna pacos). Folia Morphol (Warsz). 2015;74:195-205 pubmed publisher
|
Li Z, Zhang F, Pan L, Zhu X, Zhang Z. Preparation and characterization of injectable Mitoxantrone poly (lactic acid)/fullerene implants for in vivo chemo-photodynamic therapy. J Photochem Photobiol B. 2015;149:51-7 pubmed publisher
|
Arcese W, Picardi A, Santarone S, De Angelis G, Cerretti R, Cudillo L, et al. Haploidentical, G-CSF-primed, unmanipulated bone marrow transplantation for patients with high-risk hematological malignancies: an update. Bone Marrow Transplant. 2015;50 Suppl 2:S24-30 pubmed publisher
|
Chin C, Chin H, Chin C, Lai E, Ng S. Engineering selection stringency on expression vector for the production of recombinant human alpha1-antitrypsin using Chinese Hamster ovary cells. BMC Biotechnol. 2015;15:44 pubmed publisher
|
Chaturvedi P, Tulsyan S, Agarwal G, Lal P, Agrawal S, Mittal R, et al. Relationship of MTHFR and NQO1 Pharmacogenetics and Chemotherapy Clinical Outcomes in Breast Cancer Patients. Biochem Genet. 2015;53:211-22 pubmed publisher
|
Charolidi N, Schilling T, Eder C. Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice. PLoS ONE. 2015;10:e0128463 pubmed publisher
|
Lutterbeck C, Kern D, Machado Ã, Kümmerer K. Evaluation of the toxic effects of four anti-cancer drugs in plant bioassays and its potency for screening in the context of waste water reuse for irrigation. Chemosphere. 2015;135:403-10 pubmed publisher
|
Kim H, Lee S, Park K, Mun C, Park Y, Yoo K. Drug-loaded gold/iron/gold plasmonic nanoparticles for magnetic targeted chemo-photothermal treatment of rheumatoid arthritis. Biomaterials. 2015;61:95-102 pubmed publisher
|
Zhang Z, Zhang S, Jin B, Wu Y, Yang X, Yu B, et al. Ciclamilast ameliorates adjuvant-induced arthritis in a rat model. Biomed Res Int. 2015;2015:786104 pubmed publisher
|
Baser O, Ganguli A, Roy S, Xie L, Cifaldi M. Impact of Switching From an Initial Tumor Necrosis Factor Inhibitor on Health Care Resource Utilization and Costs Among Patients With Rheumatoid Arthritis. Clin Ther. 2015;37:1454-65 pubmed publisher
|
Li Z, Ou Yang Y, Liu Y, Wang Y, Zhu X, Zhang Z. Folic acid-conjugated TiO2-doped mesoporous carbonaceous nanocomposites loaded with Mitoxantrone HCl for chemo-photodynamic therapy. Photochem Photobiol Sci. 2015;14:1197-206 pubmed publisher
|
Landewé R, Smolen J, Florentinus S, Chen S, Guérette B, van der Heijde D. Existing joint erosions increase the risk of joint space narrowing independently of clinical synovitis in patients with early rheumatoid arthritis. Arthritis Res Ther. 2015;17:133 pubmed publisher
|
Ewees M, Abdelghany T, Abdel Aziz A, Abdel Bakky M. All-trans retinoic acid mitigates methotrexate-induced liver injury in rats; relevance of retinoic acid signaling pathway. Naunyn Schmiedebergs Arch Pharmacol. 2015;388:931-8 pubmed publisher
|
Vanhoecke B, Bateman E, Mayo B, Vanlancker E, Stringer A, Thorpe D, et al. Dark Agouti rat model of chemotherapy-induced mucositis: establishment and current state of the art. Exp Biol Med (Maywood). 2015;240:725-41 pubmed publisher
|
Kaas C, Bolt G, Hansen J, Andersen M, Kristensen C. Deep sequencing reveals different compositions of mRNA transcribed from the F8 gene in a panel of FVIII-producing CHO cell lines. Biotechnol J. 2015;10:1081-9 pubmed publisher
|
Gan Y, Dang N, Qu Z, Shi R, Ding L, Wang L, et al. GLP-1-Exendin-4/IgG4 (Fc) fusion protein as a novel drug for diabetes treatment. Exp Clin Endocrinol Diabetes. 2015;123:371-5 pubmed publisher
|
Chen X, Hansen D, Merry G, DeJarnette C, Nolen G, Sloper D, et al. Developing osteoblasts as an endpoint for the mouse embryonic stem cell test. Reprod Toxicol. 2015;53:131-40 pubmed publisher
|
Lee S, Park W, Park S, Shim S, Baek H, Yoo D, et al. Low baseline interleukin-17A levels are associated with better treatment response at 12 weeks to tocilizumab therapy in rheumatoid arthritis patients. J Immunol Res. 2015;2015:487230 pubmed publisher
|
Peters L, Karmon O, David Kadoch G, Hazan R, Yu T, Glickman M, et al. The protein quality control machinery regulates its misassembled proteasome subunits. PLoS Genet. 2015;11:e1005178 pubmed publisher
|
Curcio M, Blanco Fernández B, Costoya A, Concheiro A, Puoci F, Alvarez Lorenzo C. Glucose cryoprotectant affects glutathione-responsive antitumor drug release from polysaccharide nanoparticles. Eur J Pharm Biopharm. 2015;93:281-92 pubmed publisher
|
Shen Y, Yang J, Zhao J, Xiao C, Xu C, Xiang Y. The switch from ER stress-induced apoptosis to autophagy via ROS-mediated JNK/p62 signals: A survival mechanism in methotrexate-resistant choriocarcinoma cells. Exp Cell Res. 2015;334:207-18 pubmed publisher
|
Ferrando Climent L, Cruz Morató C, Marco Urrea E, Vicent T, Sarrà M, Rodriguez Mozaz S, et al. Non conventional biological treatment based on Trametes versicolor for the elimination of recalcitrant anticancer drugs in hospital wastewater. Chemosphere. 2015;136:9-19 pubmed publisher
|
Fikry E, Safar M, Hasan W, Fawzy H, El Denshary E. Bone Marrow and Adipose-Derived Mesenchymal Stem Cells Alleviate Methotrexate-Induced Pulmonary Fibrosis in Rat: Comparison with Dexamethasone. J Biochem Mol Toxicol. 2015;29:321-9 pubmed publisher
|
Liu Y, Lv J, Yang B, Liu F, Tian Z, Cai Y, et al. Lycium barbarum polysaccharide attenuates type II collagen-induced arthritis in mice. Int J Biol Macromol. 2015;78:318-23 pubmed publisher
|
Tang X, Chen J, Fang J, Sun X, Qin M, Li J, et al. Similar outcomes of allogeneic hematopoietic cell transplantation from unrelated donor and umbilical cord blood vs. sibling donor for pediatric acute myeloid leukemia: Multicenter experience in China. Pediatr Transplant. 2015;19:413-21 pubmed publisher
|
Huber S, Wege A, Bernhardt G, Buschauer A, Brockhoff G. Topotecan-induced ABCG2 expression in MCF-7 cells is associated with decreased CD24 and EpCAM expression and a loss of tumorigenicity. Cytometry A. 2015;87:707-16 pubmed publisher
|
Tian D, Jia W, Liu X, Wang D, Liu J, Dong J, et al. Methylation and its role in the disposition of tanshinol, a cardiovascular carboxylic catechol from Salvia miltiorrhiza roots (Danshen). Acta Pharmacol Sin. 2015;36:627-43 pubmed publisher
|
Scarselli A, Di Cesare S, Capponi C, Cascioli S, Romiti M, Di Matteo G, et al. Longitudinal Evaluation of Immune Reconstitution and B-cell Function After Hematopoietic Cell Transplantation for Primary Immunodeficiency. J Clin Immunol. 2015;35:373-83 pubmed publisher
|
Smolen J, Weinblatt M, van der Heijde D, Rigby W, van Vollenhoven R, Bingham C, et al. Efficacy and safety of tabalumab, an anti-B-cell-activating factor monoclonal antibody, in patients with rheumatoid arthritis who had an inadequate response to methotrexate therapy: results from a phase III multicentre, randomised, double-blind study. Ann Rheum Dis. 2015;74:1567-70 pubmed publisher
|
Kingsbury S, Tharmanathan P, Arden N, Batley M, Birrell F, Cocks K, et al. Pain reduction with oral methotrexate in knee osteoarthritis, a pragmatic phase iii trial of treatment effectiveness (PROMOTE): study protocol for a randomized controlled trial. Trials. 2015;16:77 pubmed publisher
|
Reinhart D, Damjanovic L, Kaisermayer C, Kunert R. Benchmarking of commercially available CHO cell culture media for antibody production. Appl Microbiol Biotechnol. 2015;99:4645-57 pubmed publisher
|
Narawa T, Yano T, Itoh T. Stereoselective recognition of amethopterin enantiomers by the rat proton-coupled folate transporter. Biol Pharm Bull. 2015;38:545-51 pubmed publisher
|
Patel J, Superko H, Martin S, Blumenthal R, Christopher Stine L. Genetic and immunologic susceptibility to statin-related myopathy. Atherosclerosis. 2015;240:260-71 pubmed publisher
|
Elliott T, Hudspith B, Rayment N, Prescott N, Petrovska L, Hermon Taylor J, et al. Defective macrophage handling of Escherichia coli in Crohn's disease. J Gastroenterol Hepatol. 2015;30:1265-74 pubmed publisher
|
Kay M, Hojati Z, Heidari M, Bazi Z, Korbekandi H. Effects of disruption of the nucleotide pattern in CRID element and Kozak sequence of interferon β on mRNA stability and protein production. Autoimmunity. 2015;48:336-43 pubmed publisher
|
Lee C, Kokolus K, Leigh N, Capitano M, Hylander B, Repasky E. Defining immunological impact and therapeutic benefit of mild heating in a murine model of arthritis. PLoS ONE. 2015;10:e0120327 pubmed publisher
|
Shah E, Siegel C, Chong K, Melmed G. Patients with Crohn's Disease Are More Likely to Remain on Biologics than Immunomodulators: A Meta-Analysis of Treatment Durability. Dig Dis Sci. 2015;60:2408-18 pubmed publisher
|
Matson K, Shaffer C, Beck G, Simonsen K. Assessment of initial serum vancomycin trough concentrations and their association with initial empirical weight-based vancomycin dosing and development of nephrotoxicity in children: a multicenter retrospective study. Pharmacotherapy. 2015;35:337-43 pubmed publisher
|
Sugiyama A, Sun J, Ueda K, Furukawa S, Takeuchi T. Effect of methotrexate on cerebellar development in infant rats. J Vet Med Sci. 2015;77:789-97 pubmed publisher
|
Ho S, Wang T, Song Z, Yang Y. IgG Aggregation Mechanism for CHO Cell Lines Expressing Excess Heavy Chains. Mol Biotechnol. 2015;57:625-34 pubmed publisher
|
Neradil J, Pavlasova G, Srámek M, Kyr M, Veselska R, Sterba J. DHFR-mediated effects of methotrexate in medulloblastoma and osteosarcoma cells: the same outcome of treatment with different doses in sensitive cell lines. Oncol Rep. 2015;33:2169-75 pubmed publisher
|
Ha T, Kim Y, Lee G. Understanding of altered N-glycosylation-related gene expression in recombinant Chinese hamster ovary cells subjected to elevated ammonium concentration by digital mRNA counting. Biotechnol Bioeng. 2015;112:1583-93 pubmed publisher
|
Tyagi K, Upadhyaya P, Sarma S, Tamboli V, Sreelakshmi Y, Sharma R. High performance liquid chromatography coupled to mass spectrometry for profiling and quantitative analysis of folate monoglutamates in tomato. Food Chem. 2015;179:76-84 pubmed publisher
|
Inui Y, Matsuoka H, Yakushijin K, Okamura A, Shimada T, Yano S, et al. Methotrexate-associated lymphoproliferative disorders: management by watchful waiting and observation of early lymphocyte recovery after methotrexate withdrawal. Leuk Lymphoma. 2015;56:3045-51 pubmed publisher
|
Asada H, Tomiyasu H, Goto Koshino Y, Fujino Y, Ohno K, Tsujimoto H. Evaluation of the drug sensitivity and expression of 16 drug resistance-related genes in canine histiocytic sarcoma cell lines. J Vet Med Sci. 2015;77:677-84 pubmed publisher
|
MacDonald C, Piper R. Puromycin- and methotrexate-resistance cassettes and optimized Cre-recombinase expression plasmids for use in yeast. Yeast. 2015;32:423-38 pubmed publisher
|
Cavicchioli L, Zanetti R, Ferraresso S, Crossan C, Barry P, Boldrin M, et al. Expression of recipient cytomegalovirus in immunosuppressed and xenotransplanted Macaca fascicularis may be related to more severe gastrointestinal lesions. Xenotransplantation. 2015;22:135-43 pubmed publisher
|
Mancardi G, Sormani M, Gualandi F, Saiz A, Carreras E, Merelli E, et al. Autologous hematopoietic stem cell transplantation in multiple sclerosis: a phase II trial. Neurology. 2015;84:981-8 pubmed publisher
|
Bluett J, Riba Garcia I, Hollywood K, Verstappen S, Barton A, Unwin R. A HPLC-SRM-MS based method for the detection and quantification of methotrexate in urine at doses used in clinical practice for patients with rheumatological disease: a potential measure of adherence. Analyst. 2015;140:1981-7 pubmed publisher
|
Kwon H, Lee J, Jeong K, Jang D, Pak Y. Fatty acylated caveolin-2 is a substrate of insulin receptor tyrosine kinase for insulin receptor substrate-1-directed signaling activation. Biochim Biophys Acta. 2015;1853:1022-34 pubmed publisher
|
Saygin C, Uzunaslan D, Hatemi G. Currently Used Biologic Agents in the Management of Behcet's Syndrome. Curr Med Chem. 2015;22:1976-85 pubmed
|
Tang Q, Yang Y, Zhao M, Liang G, Wu H, Liu Q, et al. Mycophenolic acid upregulates miR-142-3P/5P and miR-146a in lupus CD4+T cells. Lupus. 2015;24:935-42 pubmed publisher
|
Misra R, Upadhyay M, Perumal V, Mohanty S. In vitro control release, cytotoxicity assessment and cellular uptake of methotrexate loaded liquid-crystalline folate nanocarrier. Biomed Pharmacother. 2015;69:102-10 pubmed publisher
|
Lee J, Noh C, Yim C, Jeong Y, Ahn S, Lee W, et al. Kinetics of the Absorption, Distribution, Metabolism, and Excretion of Lobeglitazone, a Novel Activator of Peroxisome Proliferator-Activated Receptor Gamma in Rats. J Pharm Sci. 2015;104:3049-59 pubmed publisher
|
Wu D, Wang Y, Sun Y, Ouyang N, Qian J. A simple, rapid and reliable liquid chromatography-mass spectrometry method for determination of methotrexate in human plasma and its application to therapeutic drug monitoring. Biomed Chromatogr. 2015;29:1197-202 pubmed publisher
|
Wang C, Mäkilä E, Kaasalainen M, Hagström M, Salonen J, Hirvonen J, et al. Dual-drug delivery by porous silicon nanoparticles for improved cellular uptake, sustained release, and combination therapy. Acta Biomater. 2015;16:206-14 pubmed publisher
|
MartÃn R, Sánchez B, Urdaci M, Langella P, Suárez J, Bermúdez Humarán L. Effect of iron on the probiotic properties of the vaginal isolate Lactobacillus jensenii CECT 4306. Microbiology. 2015;161:708-18 pubmed publisher
|
Emery P, Hammoudeh M, Combe B. Etanercept tapering in rheumatoid arthritis. N Engl J Med. 2015;372:489-90 pubmed publisher
|
Chng J, Wang T, Nian R, Lau A, Hoi K, Ho S, et al. Cleavage efficient 2A peptides for high level monoclonal antibody expression in CHO cells. MAbs. 2015;7:403-12 pubmed publisher
|
Wang J, Li G. Mechanisms of methotrexate resistance in osteosarcoma cell lines and strategies for overcoming this resistance. Oncol Lett. 2015;9:940-944 pubmed
|
Patel S, Kusano A, Truong A, Stelzer K, Laramore G. Fast neutron radiotherapy in the treatment of malignant pleural mesothelioma. Am J Clin Oncol. 2015;38:47-50 pubmed publisher
|
Tan Y, Ng Q, Jia Q, Kwang J, He F. A novel humanized antibody neutralizes H5N1 influenza virus via two different mechanisms. J Virol. 2015;89:3712-22 pubmed publisher
|
Aaltonen K, Joensuu J, Virkki L, Sokka T, Aronen P, Relas H, et al. Rates of serious infections and malignancies among patients with rheumatoid arthritis receiving either tumor necrosis factor inhibitor or rituximab therapy. J Rheumatol. 2015;42:372-8 pubmed publisher
|
Frank M, Hennenberg E, Eyking A, Runzi M, Gerken G, Scott P, et al. TLR signaling modulates side effects of anticancer therapy in the small intestine. J Immunol. 2015;194:1983-95 pubmed publisher
|
Jung E, Han K, Kwon H, Patnaik B, Kim W, Hur G, et al. Anti-inflammatory activity of sappanchalcone isolated from Caesalpinia sappan L. in a collagen-induced arthritis mouse model. Arch Pharm Res. 2015;38:973-83 pubmed publisher
|
Kozaki T, Tagashira M, Yamanishi K, Ellis B, Kayanoki T, Ooishi R, et al. Evaluation of drug-drug interaction between the novel cPLA2 inhibitor AK106-001616 and methotrexate in rheumatoid arthritis patients. Xenobiotica. 2015;45:615-24 pubmed publisher
|
Hu Y, Wang L, Wang L, Wu X, Wu X, Gu Y, et al. Preferential cytotoxicity of bortezomib toward highly malignant human liposarcoma cells via suppression of MDR1 expression and function. Toxicol Appl Pharmacol. 2015;283:1-8 pubmed publisher
|
Liu X, Kuriyan A, Amescua G. A painful red eye. JAMA Ophthalmol. 2015;133:95-6 pubmed publisher
|
Zhang W, Zhang Q, Tian X, Zhao H, Lu W, Zhen J, et al. Population pharmacokinetics of high-dose methotrexate after intravenous administration in Chinese osteosarcoma patients from a single institution. Chin Med J (Engl). 2015;128:111-8 pubmed publisher
|
Trendowski M, Wong V, Yu G, Fondy T. Enlargement and multinucleation of u937 leukemia and MCF7 breast carcinoma cells by antineoplastic agents to enhance sensitivity to low frequency ultrasound and to DNA-directed anticancer agents. Anticancer Res. 2015;35:65-76 pubmed
|
López Molina D, Chazarra S, How C, Pruidze N, Navarro Perán E, GarcÃa Cánovas F, et al. Cinnamate of inulin as a vehicle for delivery of colonic drugs. Int J Pharm. 2015;479:96-102 pubmed publisher
|
Tanaka E, Inoue E, Hoshi D, Shimizu Y, Kobayashi A, Sugimoto N, et al. Cost-effectiveness of tocilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, versus methotrexate in patients with rheumatoid arthritis using real-world data from the IORRA observational cohort study. Mod Rheumatol. 2015;25:503-13 pubmed publisher
|
Yano K, Mita S, Morimoto K, Haraguchi T, Arakawa H, Yoshida M, et al. Multiple Linear Regression Analysis Indicates Association of P-Glycoprotein Substrate or Inhibitor Character with Bitterness Intensity, Measured with a Sensor. J Pharm Sci. 2015;104:2789-94 pubmed publisher
|
Revalde J, Li Y, Hawkins B, Rosengren R, Paxton J. Heterocyclic cyclohexanone monocarbonyl analogs of curcumin can inhibit the activity of ATP-binding cassette transporters in cancer multidrug resistance. Biochem Pharmacol. 2015;93:305-17 pubmed publisher
|
Meng X, Qi X, Guo H, Cai M, Li C, Zhu J, et al. Novel role for non-homologous end joining in the formation of double minutes in methotrexate-resistant colon cancer cells. J Med Genet. 2015;52:135-44 pubmed publisher
|
Panther D, Nino T, Macknet K, Macknet C. Eruptive keratoacanthomas as a complication of fractionated CO2 laser resurfacing and combination therapy with imiquimod and intralesional methotrexate. Dermatol Surg. 2015;41:172-5 pubmed publisher
|
Winocur G, Wojtowicz J, Tannock I. Memory loss in chemotherapy-treated rats is exacerbated in high-interference conditions and related to suppression of hippocampal neurogenesis. Behav Brain Res. 2015;281:239-44 pubmed publisher
|
Tawfik M. Combination of coenzyme Q10 with methotrexate suppresses Freund's complete adjuvant-induced synovial inflammation with reduced hepatotoxicity in rats: Effect on oxidative stress and inflammation. Int Immunopharmacol. 2015;24:80-7 pubmed publisher
|
Zhou F, Yu Y, Zhou X, Xian C. Methotrexate chemotherapy triggers touch-evoked pain and increased CGRP-positive sensory fibres in the tibial periosteum of young rats. Bone. 2015;73:24-31 pubmed publisher
|
Crowley J, Weinberg J, Wu J, Robertson A, Van Voorhees A. Treatment of nail psoriasis: best practice recommendations from the Medical Board of the National Psoriasis Foundation. JAMA Dermatol. 2015;151:87-94 pubmed publisher
|
Ieva R, Schrempp S, Opaliński L, Wollweber F, Höß P, Heißwolf A, et al. Mgr2 functions as lateral gatekeeper for preprotein sorting in the mitochondrial inner membrane. Mol Cell. 2014;56:641-52 pubmed publisher
|
Vishwanathan N, Yongky A, Johnson K, Fu H, Jacob N, Le H, et al. Global insights into the Chinese hamster and CHO cell transcriptomes. Biotechnol Bioeng. 2015;112:965-76 pubmed publisher
|
Nowak D, Liem N, Mossner M, Klaumünzer M, Papa R, Nowak V, et al. Variegated clonality and rapid emergence of new molecular lesions in xenografts of acute lymphoblastic leukemia are associated with drug resistance. Exp Hematol. 2015;43:32-43.e1-35 pubmed publisher
|
Sarker S, Kodali S, Weber F. A new meaning to butterflies in the stomach. Gastroenterology. 2015;148:e12-3 pubmed publisher
|
Pinto M, Moura C, Nunes C, Segundo M, Costa Lima S, Reis S. A new topical formulation for psoriasis: development of methotrexate-loaded nanostructured lipid carriers. Int J Pharm. 2014;477:519-26 pubmed publisher
|
Arai S, Arora M, Wang T, Spellman S, He W, Couriel D, et al. Increasing incidence of chronic graft-versus-host disease in allogeneic transplantation: a report from the Center for International Blood and Marrow Transplant Research. Biol Blood Marrow Transplant. 2015;21:266-74 pubmed publisher
|
Keystone E, Taylor P, Drescher E, Schlichting D, Beattie S, Berclaz P, et al. Safety and efficacy of baricitinib at 24 weeks in patients with rheumatoid arthritis who have had an inadequate response to methotrexate. Ann Rheum Dis. 2015;74:333-40 pubmed publisher
|
Laverdière I, Guillemette C, Tamouza R, Loiseau P, Peffault De Latour R, Robin M, et al. Cyclosporine and methotrexate-related pharmacogenomic predictors of acute graft-versus-host disease. Haematologica. 2015;100:275-83 pubmed publisher
|
Wang Y, Yuan L, Yang X, Wei D, Wang B, Sun X, et al. A chimeric antibody targeting CD147 inhibits hepatocellular carcinoma cell motility via FAK-PI3K-Akt-Girdin signaling pathway. Clin Exp Metastasis. 2015;32:39-53 pubmed publisher
|
Polcari I, Moon A, Mathes E, Gilmore E, Paller A. Headaches as a presenting symptom of linear morphea en coup de sabre. Pediatrics. 2014;134:e1715-9 pubmed publisher
|
Tanimoto A, Ogawa Y, Oki C, Kimoto Y, Nozawa K, Amano W, et al. Pharmacological properties of JTE-052: a novel potent JAK inhibitor that suppresses various inflammatory responses in vitro and in vivo. Inflamm Res. 2015;64:41-51 pubmed publisher
|
Chan T, Zheng J, Zhu L, Grewal T, Murray M, Zhou F. Putative transmembrane domain 6 of the human organic anion transporting polypeptide 1A2 (OATP1A2) influences transporter substrate binding, protein trafficking, and quality control. Mol Pharm. 2015;12:111-9 pubmed publisher
|
Johnson Farley N, Veliz J, Bhagavathi S, Bertino J. ABT-199, a BH3 mimetic that specifically targets Bcl-2, enhances the antitumor activity of chemotherapy, bortezomib and JQ1 in "double hit" lymphoma cells. Leuk Lymphoma. 2015;56:2146-52 pubmed publisher
|
Emery P, Hammoudeh M, Fitzgerald O, Combe B, Martin Mola E, Buch M, et al. Sustained remission with etanercept tapering in early rheumatoid arthritis. N Engl J Med. 2014;371:1781-92 pubmed publisher
|
Kadia T, Kantarjian H, Thomas D, O Brien S, Estrov Z, Ravandi F, et al. Phase II study of methotrexate, vincristine, pegylated-asparaginase, and dexamethasone (MOpAD) in patients with relapsed/refractory acute lymphoblastic leukemia. Am J Hematol. 2015;90:120-4 pubmed publisher
|
Emery P, Burmester G, Bykerk V, Combe B, Furst D, Barré E, et al. Evaluating drug-free remission with abatacept in early rheumatoid arthritis: results from the phase 3b, multicentre, randomised, active-controlled AVERT study of 24?months, with a 12-month, double-blind treatment period. Ann Rheum Dis. 2015;74:19-26 pubmed publisher
|
Hoelzer D, Walewski J, Dohner H, Viardot A, Hiddemann W, Spiekermann K, et al. Improved outcome of adult Burkitt lymphoma/leukemia with rituximab and chemotherapy: report of a large prospective multicenter trial. Blood. 2014;124:3870-9 pubmed publisher
|
Verschueren P, De Cock D, Corluy L, Joos R, Langenaken C, Taelman V, et al. Methotrexate in combination with other DMARDs is not superior to methotrexate alone for remission induction with moderate-to-high-dose glucocorticoid bridging in early rheumatoid arthritis after 16 weeks of treatment: the CareRA trial. Ann Rheum Dis. 2015;74:27-34 pubmed publisher
|
Hamilton B, Rybicki L, Dean R, Majhail N, Haddad H, Abounader D, et al. Cyclosporine in combination with mycophenolate mofetil versus methotrexate for graft versus host disease prevention in myeloablative HLA-identical sibling donor allogeneic hematopoietic cell transplantation. Am J Hematol. 2015;90:144-8 pubmed publisher
|
Levinsen M, Rosthøj S, Nygaard U, Heldrup J, Harila Saari A, Jonsson O, et al. Myelotoxicity after high-dose methotrexate in childhood acute leukemia is influenced by 6-mercaptopurine dosing but not by intermediate thiopurine methyltransferase activity. Cancer Chemother Pharmacol. 2015;75:59-66 pubmed publisher
|
Xu M, Jin H, Xu C, Sun B, Mao Z, Bi W, et al. miR-382 inhibits tumor growth and enhance chemosensitivity in osteosarcoma. Oncotarget. 2014;5:9472-83 pubmed
|
Wright K, Panetta J, Onar Thomas A, Reddick W, Patay Z, Qaddoumi I, et al. Delayed methotrexate excretion in infants and young children with primary central nervous system tumors and postoperative fluid collections. Cancer Chemother Pharmacol. 2015;75:27-35 pubmed publisher
|
Pirkmajer S, Kulkarni S, Tom R, Ross F, Hawley S, Hardie D, et al. Methotrexate promotes glucose uptake and lipid oxidation in skeletal muscle via AMPK activation. Diabetes. 2015;64:360-9 pubmed publisher
|
Liu L, Aleksandrowicz E, Fan P, Schönsiegel F, Zhang Y, Sähr H, et al. Enrichment of c-Met+ tumorigenic stromal cells of giant cell tumor of bone and targeting by cabozantinib. Cell Death Dis. 2014;5:e1471 pubmed publisher
|
Finckh A, Mc Carthy G, Madigan A, Van Linthoudt D, Weber M, Neto D, et al. Methotrexate in chronic-recurrent calcium pyrophosphate deposition disease: no significant effect in a randomized crossover trial. Arthritis Res Ther. 2014;16:458 pubmed publisher
|
Tuure L, Hämäläinen M, Moilanen T, Moilanen E. Aurothiomalate inhibits the expression of mPGES-1 in primary human chondrocytes. Scand J Rheumatol. 2015;44:74-9 pubmed publisher
|
Vrhovac I, Balen Eror D, Klessen D, Burger C, Breljak D, Kraus O, et al. Localizations of Na(+)-D-glucose cotransporters SGLT1 and SGLT2 in human kidney and of SGLT1 in human small intestine, liver, lung, and heart. Pflugers Arch. 2015;467:1881-98 pubmed publisher
|
Lv M, Zhao X, Hu Y, Chang Y, Zhao X, Kong Y, et al. Monocytic and promyelocytic myeloid-derived suppressor cells may contribute to G-CSF-induced immune tolerance in haplo-identical allogeneic hematopoietic stem cell transplantation. Am J Hematol. 2015;90:E9-E16 pubmed publisher
|
Jiang R, Dong J, Li X, Du F, Jia W, Xu F, et al. Molecular mechanisms governing different pharmacokinetics of ginsenosides and potential for ginsenoside-perpetrated herb-drug interactions on OATP1B3. Br J Pharmacol. 2015;172:1059-73 pubmed publisher
|
Levin I, Cohen A, Almog B. Reply: To PMID 24657132. Am J Obstet Gynecol. 2015;212:122 pubmed publisher
|
Sholapurkar S. Methotrexate for ectopic pregnancy: success rates and avoidance of embryopathy. Am J Obstet Gynecol. 2015;212:121-2 pubmed publisher
|
Wong J, Bhat R, Hockman D, Logan M, Chen C, Levin A, et al. Recombinant hepatitis C virus envelope glycoprotein vaccine elicits antibodies targeting multiple epitopes on the envelope glycoproteins associated with broad cross-neutralization. J Virol. 2014;88:14278-88 pubmed publisher
|
Takeshita J, Wang S, Shin D, Callis Duffin K, Krueger G, Kalb R, et al. Comparative effectiveness of less commonly used systemic monotherapies and common combination therapies for moderate to severe psoriasis in the clinical setting. J Am Acad Dermatol. 2014;71:1167-75 pubmed publisher
|
Cohen A, Bibi G, Almog B, Tsafrir Z, Levin I. Second-dose methotrexate in ectopic pregnancies: the role of beta human chorionic gonadotropin. Fertil Steril. 2014;102:1646-9 pubmed publisher
|
Chioukh R, Noel Hudson M, Ribes S, Fournier N, Becquemont L, Verstuyft C. Proton pump inhibitors inhibit methotrexate transport by renal basolateral organic anion transporter hOAT3. Drug Metab Dispos. 2014;42:2041-8 pubmed publisher
|
Perinelli D, Bonacucina G, Pucciarelli S, Cespi M, Casettari L, Polzonetti V, et al. Could albumin affect the self-assembling properties of a block co-polymer system and drug release? An in-vitro study. Pharm Res. 2015;32:1094-104 pubmed publisher
|
Weinblatt M, Genovese M, Ho M, Hollis S, Rosiak Jedrychowicz K, Kavanaugh A, et al. Effects of fostamatinib, an oral spleen tyrosine kinase inhibitor, in rheumatoid arthritis patients with an inadequate response to methotrexate: results from a phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study. Arthritis Rheumatol. 2014;66:3255-64 pubmed publisher
|
Jin H, Cho H, Kim W, Mun J, Song M, Kim H, et al. Primary thyroid marginal zone B-cell lymphoma in a patient with psoriatic arthritis treated with etanercept. J Am Acad Dermatol. 2014;71:e152-3 pubmed publisher
|
Sathyamurthy M, Kim C, Bang Y, Kim Y, Jang J, Lee G. Characterization and expression of proprotein convertases in CHO cells: Efficient proteolytic maturation of human bone morphogenetic protein-7. Biotechnol Bioeng. 2015;112:560-8 pubmed publisher
|
Trucco L, Andreoli V, Núñez N, Maccioni M, Bocco J. Krüppel-like factor 6 interferes with cellular transformation induced by the H-ras oncogene. FASEB J. 2014;28:5262-76 pubmed publisher
|
Joly M, Martin R, Mitra Kaushik S, Phillips L, D Angona A, Richards S, et al. Transient low-dose methotrexate generates B regulatory cells that mediate antigen-specific tolerance to alglucosidase alfa. J Immunol. 2014;193:3947-58 pubmed publisher
|
Badr M, Kopp C, Theison S, Meyer J, Trommer W. Methotrexate-gelonin conjugate - an inhibitor of MCF-7 cells expressing the dihydrofolate receptor. Biol Chem. 2014;395:1461-6 pubmed publisher
|
Januchowski R, Zawierucha P, Rucinski M, Zabel M. Microarray-based detection and expression analysis of extracellular matrix proteins in drug?resistant ovarian cancer cell lines. Oncol Rep. 2014;32:1981-90 pubmed publisher
|
Abdel M, Figgie M. Surgical management of the juvenile idiopathic arthritis patient with multiple joint involvement. Orthop Clin North Am. 2014;45:435-42 pubmed publisher
|
Sero V, Tavanti E, Vella S, Hattinger C, Fanelli M, Michelacci F, et al. Targeting polo-like kinase 1 by NMS-P937 in osteosarcoma cell lines inhibits tumor cell growth and partially overcomes drug resistance. Invest New Drugs. 2014;32:1167-80 pubmed publisher
|
Georgiou K, Nadhanan R, Fan C, Xian C. Methotrexate-induced bone marrow adiposity is mitigated by folinic acid supplementation through the regulation of Wnt/β-catenin signalling. J Cell Physiol. 2015;230:648-56 pubmed publisher
|
Funk R, van Haandel L, Leeder J, Becker M. Folate depletion and increased glutamation in juvenile idiopathic arthritis patients treated with methotrexate. Arthritis Rheumatol. 2014;66:3476-85 pubmed publisher
|
Piras A, Sandreschi S, Malliappan S, Dash M, Bartoli C, Dinucci D, et al. Surface decorated poly(ester-ether-urethane)s nanoparticles: a versatile approach towards clinical translation. Int J Pharm. 2014;475:523-35 pubmed publisher
|
Oberoi S, Trehan A, Marwaha R. Medication errors on oral chemotherapy in children with acute lymphoblastic leukemia in a developing country. Pediatr Blood Cancer. 2014;61:2218-22 pubmed publisher
|
Ylinen E, Jahnukainen K, Saarinen Pihkala U, Jahnukainen T. Assessment of renal function during high-dose methotrexate treatment in children with acute lymphoblastic leukemia. Pediatr Blood Cancer. 2014;61:2199-202 pubmed publisher
|
Huizinga T, Conaghan P, Martin Mola E, Schett G, Amital H, Xavier R, et al. Clinical and radiographic outcomes at 2 years and the effect of tocilizumab discontinuation following sustained remission in the second and third year of the ACT-RAY study. Ann Rheum Dis. 2015;74:35-43 pubmed publisher
|
Calza P, Medana C, Sarro M, Rosato V, Aigotti R, Baiocchi C, et al. Photocatalytic degradation of selected anticancer drugs and identification of their transformation products in water by liquid chromatography-high resolution mass spectrometry. J Chromatogr A. 2014;1362:135-44 pubmed publisher
|
Chande N, Wang Y, Macdonald J, McDonald J. Methotrexate for induction of remission in ulcerative colitis. Cochrane Database Syst Rev. 2014;:CD006618 pubmed publisher
|
Patel V, Wang Y, Macdonald J, McDonald J, Chande N. Methotrexate for maintenance of remission in Crohn's disease. Cochrane Database Syst Rev. 2014;:CD006884 pubmed publisher
|
Alexander S, Kraveka J, Weitzman S, Lowe E, Smith L, Lynch J, et al. Advanced stage anaplastic large cell lymphoma in children and adolescents: results of ANHL0131, a randomized phase III trial of APO versus a modified regimen with vinblastine: a report from the children's oncology group. Pediatr Blood Cancer. 2014;61:2236-42 pubmed publisher
|
Yoon S, Zapata M, Singh A, Jo W, Spencer N, Choi Y. Gamma secretase inhibitors enhance vincristine-induced apoptosis in T-ALL in a NOTCH-independent manner. Apoptosis. 2014;19:1616-26 pubmed publisher
|
Kosmaczewska A, Ciszak L, Swierkot J, Szteblich A, Kosciow K, Frydecka I. Exogenous IL-2 controls the balance in Th1, Th17, and Treg cell distribution in patients with progressive rheumatoid arthritis treated with TNF-alpha inhibitors. Inflammation. 2015;38:765-74 pubmed publisher
|
Fleischmann R, van der Heijde D, Koenig A, Pedersen R, Szumski A, Marshall L, et al. How much does Disease Activity Score in 28 joints ESR and CRP calculations underestimate disease activity compared with the Simplified Disease Activity Index?. Ann Rheum Dis. 2015;74:1132-7 pubmed publisher
|
Wang Z, Zheng X, Yan H, Li D, Wang H. Good outcome of haploidentical hematopoietic SCT as a salvage therapy in children and adolescents with acquired severe aplastic anemia. Bone Marrow Transplant. 2014;49:1481-5 pubmed publisher
|
Zhang H, He X, Wang C, Wang Y, Chen Y, Li J, et al. Impact of SLCO1B1 521T > C variant on leucovorin rescue and risk of relapse in childhood acute lymphoblastic leukemia treated with high-dose methotrexate. Pediatr Blood Cancer. 2014;61:2203-7 pubmed publisher
|
Raven N, Rasche S, Kuehn C, Anderlei T, Klöckner W, Schuster F, et al. Scaled-up manufacturing of recombinant antibodies produced by plant cells in a 200-L orbitally-shaken disposable bioreactor. Biotechnol Bioeng. 2015;112:308-21 pubmed publisher
|
Byrne S, Lim M. N-methyl-D-aspartate receptor antibody encephalitis: how much treatment is enough?. Dev Med Child Neurol. 2015;57:14-5 pubmed publisher
|
McDonald J, Wang Y, Tsoulis D, Macdonald J, Feagan B. Methotrexate for induction of remission in refractory Crohn's disease. Cochrane Database Syst Rev. 2014;:CD003459 pubmed publisher
|
McLaren J, Barnhart K, Sammel M, Appleby D, Butts S. Success of the two-dose methotrexate protocol for treatment of ectopic pregnancy in women with a history of prior ectopic pregnancy. J Reprod Med. 2014;59:379-84 pubmed
|
Balar A, Milowsky M. Cytotoxic and DNA-targeted therapy in urothelial cancer: have we squeezed the lemon enough?. Cancer. 2015;121:179-87 pubmed publisher
|
Bogado R, Pezuk J, de Oliveira H, Tone L, Brassesco M. BI 6727 and GSK461364 suppress growth and radiosensitize osteosarcoma cells, but show limited cytotoxic effects when combined with conventional treatments. Anticancer Drugs. 2015;26:56-63 pubmed publisher
|
Kim S, Park S, Kang E, Choi J, Lim D, Ko Y, et al. Induction treatment with SMILE and consolidation with autologous stem cell transplantation for newly diagnosed stage IV extranodal natural killer/T-cell lymphoma patients. Ann Hematol. 2015;94:71-8 pubmed publisher
|
Hardwick R, Clarke J, Lake A, Canet M, Anumol T, Street S, et al. Increased susceptibility to methotrexate-induced toxicity in nonalcoholic steatohepatitis. Toxicol Sci. 2014;142:45-55 pubmed publisher
|
Castellino S, Ullrich N, Whelen M, Lange B. Developing interventions for cancer-related cognitive dysfunction in childhood cancer survivors. J Natl Cancer Inst. 2014;106: pubmed publisher
|
He Z, Wei W, Li S, Ling Q, Liao K, Wang X. Anti-allodynic effects of obtusifolin and gluco-obtusifolin against inflammatory and neuropathic pain. Biol Pharm Bull. 2014;37:1606-16 pubmed
|
Tanaka S, Mitsuda S, Shimizu N. How a replication origin and matrix attachment region accelerate gene amplification under replication stress in mammalian cells. PLoS ONE. 2014;9:e103439 pubmed publisher
|
Tan K, Cooney J, Jensen D, Li Y, Paxton J, Birch N, et al. Hop-derived prenylflavonoids are substrates and inhibitors of the efflux transporter breast cancer resistance protein (BCRP/ABCG2). Mol Nutr Food Res. 2014;58:2099-110 pubmed publisher
|
Rytting M, Thomas D, O Brien S, Ravandi Kashani F, Jabbour E, Franklin A, et al. Augmented Berlin-Frankfurt-Münster therapy in adolescents and young adults (AYAs) with acute lymphoblastic leukemia (ALL). Cancer. 2014;120:3660-8 pubmed publisher
|
Han T, Zhu X, Wang J, Zhao H, Ma Q, Zhao J, et al. Establishment and characterization of a cisplatin‑resistant human osteosarcoma cell line. Oncol Rep. 2014;32:1133-9 pubmed publisher
|
Guerriero E, Simon N, Nelken B, Baldeyrou B, Djobo B, Vasseur M, et al. Unexpected overestimation of methotrexate plasma concentrations: analysis of a single center pediatric population. Ther Drug Monit. 2014;36:499-504 pubmed publisher
|
Zgheib N, Akra Ismail M, Aridi C, Mahfouz R, Abboud M, Solh H, et al. Genetic polymorphisms in candidate genes predict increased toxicity with methotrexate therapy in Lebanese children with acute lymphoblastic leukemia. Pharmacogenet Genomics. 2014;24:387-96 pubmed publisher
|
Valenzuela M, Glorieux C, Stockis J, Sid B, Sandoval J, Felipe K, et al. Retinoic acid synergizes ATO-mediated cytotoxicity by precluding Nrf2 activity in AML cells. Br J Cancer. 2014;111:874-82 pubmed publisher
|
Humme D, Nast A, Erdmann R, Vandersee S, Beyer M. Systematic review of combination therapies for mycosis fungoides. Cancer Treat Rev. 2014;40:927-33 pubmed publisher
|
Boucherle B, Bertrand J, Maurin B, Renard B, Fortuné A, Tremblier B, et al. A new 9-alkyladenine-cyclic methylglyoxal diadduct activates wt- and F508del-cystic fibrosis transmembrane conductance regulator (CFTR) in vitro and in vivo. Eur J Med Chem. 2014;83:455-65 pubmed publisher
|
Lee S, Park S, Lee S, Lee S, Son M, Choi Y, et al. Synoviocyte apoptosis may differentiate responder and non-responder patients to methotrexate treatment in rheumatoid arthritis. Arch Pharm Res. 2014;37:1286-94 pubmed publisher
|
Symmonds M, Kuker W, Schulz U. Clinical reasoning: progressive visuospatial problems in a 71-year-old man. Neurology. 2014;83:e6-10 pubmed publisher
|
Lakkakula J, Maçedo Krause R. A vision for cyclodextrin nanoparticles in drug delivery systems and pharmaceutical applications. Nanomedicine (Lond). 2014;9:877-94 pubmed publisher
|
Liu C, Layfield J, Stewart R, French J, Hanoian P, Asbury J, et al. Probing the electrostatics of active site microenvironments along the catalytic cycle for Escherichia coli dihydrofolate reductase. J Am Chem Soc. 2014;136:10349-60 pubmed publisher
|
Michaud T, Rho Y, Shamliyan T, Kuntz K, Choi H. The comparative safety of tumor necrosis factor inhibitors in rheumatoid arthritis: a meta-analysis update of 44 trials. Am J Med. 2014;127:1208-32 pubmed publisher
|
Necessary C, Roffwarg D, ELLIS D. Reticulated hyperpigmentation following chemotherapy for radiation-induced osteosarcoma. J Am Acad Dermatol. 2014;71:e23-4 pubmed publisher
|
Ram R, Herscovici C, Dahan D, Israeli M, Dreyer J, Peck A, et al. Tailoring the GVHD prophylaxis regimen according to transplantation associated toxicities-Substituting the 3rd dose of methotrexate to mycophenolate mofetil. Leuk Res. 2014;38:913-7 pubmed publisher
|
Schmiegelow K, Nielsen S, Frandsen T, Nersting J. Mercaptopurine/Methotrexate maintenance therapy of childhood acute lymphoblastic leukemia: clinical facts and fiction. J Pediatr Hematol Oncol. 2014;36:503-17 pubmed publisher
|
Holdhoff M, Ambady P, Abdelaziz A, Sarai G, Bonekamp D, Blakeley J, et al. High-dose methotrexate with or without rituximab in newly diagnosed primary CNS lymphoma. Neurology. 2014;83:235-9 pubmed publisher
|
Vora A, Goulden N, Mitchell C, Hancock J, Hough R, Rowntree C, et al. Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): a randomised controlled trial. Lancet Oncol. 2014;15:809-18 pubmed publisher
|
Rathinam S, Babu M, Thundikandy R, Kanakath A, Nardone N, Esterberg E, et al. A randomized clinical trial comparing methotrexate and mycophenolate mofetil for noninfectious uveitis. Ophthalmology. 2014;121:1863-70 pubmed publisher
|
Burmester G, Kivitz A, Kupper H, Arulmani U, Florentinus S, Goss S, et al. Response to H Zeidler's comments on the CONCERTO study. Ann Rheum Dis. 2014;73:e51 pubmed publisher
|
Zou B, Han Z, Wang Z, Bian J, Xu J, Wang H, et al. Neoadjuvant therapy combined with a BMP regimen for treating penile cancer patients with lymph node metastasis: a retrospective study in China. J Cancer Res Clin Oncol. 2014;140:1733-8 pubmed publisher
|
Rashidi A, Maherus E. After the treated mole. Blood. 2014;123:2757 pubmed
|
Heath J, Burgett S, Gaca A, Jaffe R, Wechsler D. Successful treatment of pediatric histiocytic sarcoma using abbreviated high-risk leukemia chemotherapy. Pediatr Blood Cancer. 2014;61:1874-6 pubmed publisher
|
Li D, Wei X, Xie K, Chen K, Li J, Fang J. A novel decoy receptor fusion protein for FGF-2 potently inhibits tumour growth. Br J Cancer. 2014;111:68-77 pubmed publisher
|
Jordan J, Plotkin S, Dietrich J. Magnetic resonance imaging observations in primary central nervous system lymphoma. JAMA Neurol. 2014;71:918-9 pubmed publisher
|
del Rincon S, Widschwendter M, Sun D, Ekholm Reed S, Tat J, Teixeira L, et al. Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints. Oncogene. 2015;34:1961-7 pubmed publisher
|
Prado A, Petroianu G, Lorke D, Chambers J. A trivalent approach for determining in vitro toxicology: Examination of oxime K027. J Appl Toxicol. 2015;35:219-27 pubmed publisher
|
Gayda S, Longenecker K, Manoj S, Judge R, Saldana S, Ruan Q, et al. Water channel in the binding site of a high affinity anti-methotrexate antibody. Biochemistry. 2014;53:3719-26 pubmed publisher
|
Sidbury R, Davis D, Cohen D, Cordoro K, Berger T, Bergman J, et al. Guidelines of care for the management of atopic dermatitis: section 3. Management and treatment with phototherapy and systemic agents. J Am Acad Dermatol. 2014;71:327-49 pubmed publisher
|
Hentrich M, Hoffmann C, Mosthaf F, Muller M, Siehl J, Wyen C, et al. Therapy of HIV-associated lymphoma-recommendations of the oncology working group of the German Study Group of Physicians in Private Practice Treating HIV-Infected Patients (DAGNÄ), in cooperation with the German AIDS Society (DAIG). Ann Hematol. 2014;93:913-21 pubmed publisher
|
Koens L, Senff N, Vermeer M, Willemze R, Jansen P. Methotrexate-associated B-cell lymphoproliferative disorders presenting in the skin: A clinicopathologic and immunophenotypical study of 10 cases. Am J Surg Pathol. 2014;38:999-1006 pubmed publisher
|
Xu M, Jin H, Xu C, Bi W, Wang Y. MiR-34c inhibits osteosarcoma metastasis and chemoresistance. Med Oncol. 2014;31:972 pubmed publisher
|
Moriarity B, Rahrmann E, Beckmann D, Conboy C, Watson A, Carlson D, et al. Simple and efficient methods for enrichment and isolation of endonuclease modified cells. PLoS ONE. 2014;9:e96114 pubmed publisher
|
Schoffelen T, Kampschreur L, van Roeden S, Wever P, den Broeder A, Nabuurs Franssen M, et al. Coxiella burnetii infection (Q fever) in rheumatoid arthritis patients with and without anti-TNF? therapy. Ann Rheum Dis. 2014;73:1436-8 pubmed publisher
|
Sun N, Galvin J, Cooper K. Cutaneous Rosai-Dorfman disease successfully treated with low-dose methotrexate. JAMA Dermatol. 2014;150:787-8 pubmed publisher
|
de Jong P, Hazes J, Han H, Huisman M, Van Zeben D, van der Lubbe P, et al. Randomised comparison of initial triple DMARD therapy with methotrexate monotherapy in combination with low-dose glucocorticoid bridging therapy; 1-year data of the tREACH trial. Ann Rheum Dis. 2014;73:1331-9 pubmed publisher
|
Puttevils D, De Vusser P, Geusens P, Dens J. Increased cardiovascular risk in patients with rheumatoid arthritis: an overview. Acta Cardiol. 2014;69:111-8 pubmed
|
Zeidler H. The issue of bioavailability of oral low dose methotrexate: should we choose only 10 mg of MTX a week in conjunction with anti-TNF therapy?. Ann Rheum Dis. 2014;73:e50 pubmed publisher
|
Conway R, Low C, Coughlan R, O Donnell M, Carey J. Methotrexate and lung disease in rheumatoid arthritis: a meta-analysis of randomized controlled trials. Arthritis Rheumatol. 2014;66:803-12 pubmed publisher
|
Fushimi K, Tanabe N, Takami M. [A retrospective study of tegafur/uracil compared with cyclophosphamide, methotrexate, and fluorouracil as adjuvant chemotherapy in patients with node-negative, triple-negative breast cancer]. Gan To Kagaku Ryoho. 2014;41:449-53 pubmed
|
Bohelay G, Bouaziz J, Nunes H, Rybojad M, Bagot M, Petit A, et al. Striking leflunomide efficacy against refractory cutaneous sarcoidosis. J Am Acad Dermatol. 2014;70:e111-3 pubmed publisher
|
den Boer E, Koch B, Huisman R, de Jonge R. Using fluorescence polarization immunoassay for determination of erythrocyte methotrexate polyglutamates, a quick and easy test?. Ther Drug Monit. 2014;36:819-23 pubmed publisher
|
Schiff M, Jaffe J, Freundlich B. Head-to-head, randomised, crossover study of oral versus subcutaneous methotrexate in patients with rheumatoid arthritis: drug-exposure limitations of oral methotrexate at doses ≥15 mg may be overcome with subcutaneous administration. Ann Rheum Dis. 2014;73:1549-51 pubmed publisher
|
Soldini D, Gaspert A, Montani M, Reineke T, Rogler G, Odze R, et al. Apoptotic enteropathy caused by antimetabolites and TNF-α antagonists. J Clin Pathol. 2014;67:582-6 pubmed publisher
|
El Mesallamy H, Rashed W, Hamdy N, Hamdy N. High-dose methotrexate in Egyptian pediatric acute lymphoblastic leukemia: the impact of ABCG2 C421A genetic polymorphism on plasma levels, what is next?. J Cancer Res Clin Oncol. 2014;140:1359-65 pubmed publisher
|
Borradori L, Joly P. Toward a practical renaming of bullous pemphigoid and all its variants: cutaneous pemphigoid. JAMA Dermatol. 2014;150:459 pubmed publisher
|
Roig B, Marquenet B, Delpla I, Bessonneau V, Sellier A, Leder C, et al. Monitoring of methotrexate chlorination in water. Water Res. 2014;57:67-75 pubmed publisher
|
Kissei M, Itoh T, Narawa T. Effect of epigallocatechin gallate on drug transport mediated by the proton-coupled folate transporter. Drug Metab Pharmacokinet. 2014;29:367-72 pubmed
|
de Rotte M, de Jong P, den Boer E, Pluijm S, Özcan B, Weel A, et al. Effect of methotrexate use and erythrocyte methotrexate polyglutamate on glycosylated hemoglobin in rheumatoid arthritis. Arthritis Rheumatol. 2014;66:2026-36 pubmed publisher
|
. In brief: otrexup--a single-use auto-injector formulation of methotrexate. Med Lett Drugs Ther. 2014;56:28 pubmed
|
Moran D, Trusk P, Pry K, Paz K, Sidransky D, Bacus S. KRAS mutation status is associated with enhanced dependency on folate metabolism pathways in non-small cell lung cancer cells. Mol Cancer Ther. 2014;13:1611-24 pubmed publisher
|
Yamakawa T, Kurosawa M, Yonezumi M, Suzuki S, Suzuki H. [Methotrexate-related lymphomatoid granulomatosis successfully treated with discontinuation of methotrexate and radiotherapy to brain]. Rinsho Ketsueki. 2014;55:321-6 pubmed
|
Kenney L, Duffey Lind E, Ebb D, Sklar C, Grier H, Diller L. Impaired testicular function after an ifosfamide-containing regimen for pediatric osteosarcoma: a case series and review of the literature. J Pediatr Hematol Oncol. 2014;36:237-40 pubmed publisher
|
Ferreri A, Ciceri F, Brandes A, Montanari M, Balzarotti M, Spina M, et al. MATILDE chemotherapy regimen for primary CNS lymphoma: results at a median follow-up of 12 years. Neurology. 2014;82:1370-3 pubmed publisher
|
Yang Z, Zhao W, Liu W, Lv Q, Dong X. Efficacy evaluation of methotrexate in the treatment of ankylosing spondylitis using meta-analysis. Int J Clin Pharmacol Ther. 2014;52:346-51 pubmed publisher
|
Kimura Y, Fujimura C, Ito Y, Takahashi T, Aiba S. Evaluation of the Multi-ImmunoTox Assay composed of 3 human cytokine reporter cells by examining immunological effects of drugs. Toxicol In Vitro. 2014;28:759-68 pubmed publisher
|
Ayad M, El Naggar A, El Naggar M. MTHFR C677T polymorphism: association with lymphoid neoplasm and effect on methotrexate therapy. Eur J Haematol. 2014;93:63-9 pubmed publisher
|
Talaat R, Abo El Atta A, Farou S, El Dosoky K. Therapeutic effect of dimethyl dimethoxy biphenyl dicarboxylate on collagen-induced arthritis in rats. Chin J Integr Med. 2015;21:846-54 pubmed publisher
|
Lossos C, Bayraktar S, Weinzierl E, Younes S, Hosein P, Tibshirani R, et al. LMO2 and BCL6 are associated with improved survival in primary central nervous system lymphoma. Br J Haematol. 2014;165:640-8 pubmed publisher
|
Kojima Y, Hagiwara S, Uehira T, Ajisawa A, Kitanaka A, Tanuma J, et al. Clinical outcomes of AIDS-related Burkitt lymphoma: a multi-institution retrospective survey in Japan. Jpn J Clin Oncol. 2014;44:318-23 pubmed publisher
|
Boots C, Gustofson R, Feinberg E. Reply of the authors. Fertil Steril. 2014;101:e24 pubmed publisher
|
Xiao C, Dahan M. The effect of methotrexate injection for treatment of an ectopic pregnancy on ovarian reserve. Fertil Steril. 2014;101:e23 pubmed publisher
|
Behera D, Pattem R, Gudi G. Effect of commonly used organic solvents on aldehyde oxidase-mediated vanillin, phthalazine and methotrexate oxidation in human, rat and mouse liver subcellular fractions. Xenobiotica. 2014;44:722-33 pubmed publisher
|
Coutre S, Othus M, Powell B, Willman C, Stock W, Paietta E, et al. Arsenic trioxide during consolidation for patients with previously untreated low/intermediate risk acute promyelocytic leukaemia may eliminate the need for maintenance therapy. Br J Haematol. 2014;165:497-503 pubmed publisher
|
Conaghan P, Peterfy C, Olech E, Kaine J, Ridley D, Dicarlo J, et al. The effects of tocilizumab on osteitis, synovitis and erosion progression in rheumatoid arthritis: results from the ACT-RAY MRI substudy. Ann Rheum Dis. 2014;73:810-6 pubmed publisher
|
Ziółkowska H, Kisiel A, Leszczynska B, Bilska K, Jankowska K, Kuźma Mroczkowska E, et al. Continuous veno-venous hemodiafiltration in methotrexate intoxication. Med Wieku Rozwoj. 2013;17:347-54 pubmed
|
Plascencia Gomez A, Calderón Rocher C, Proy Trujillo H, Moreno Coutiño G. Neoadjuvant intralesional methotrexate before surgery in squamous cell carcinoma. Dermatol Surg. 2014;40:584-6 pubmed publisher
|
Prashad K, Mehra S. Dynamics of unfolded protein response in recombinant CHO cells. Cytotechnology. 2015;67:237-54 pubmed publisher
|
Furumiya M, Inoue K, Nishijima C, Yamashiro T, Inaoka E, Ohta K, et al. Noncompetitive inhibition of proton-coupled folate transporter by myricetin. Drug Metab Pharmacokinet. 2014;29:312-6 pubmed
|
Perez Martín L, De Leon Luis J, Gámez Alderete F, Bravo C, Perez F, Aguaron A, et al. [Laparoscopic management of a spontaneous live monochorionic monoamniotic twin tubal ectopic pregnancy. A case report]. Ginecol Obstet Mex. 2013;81:612-5 pubmed
|
Dougados M, Kissel K, Conaghan P, Mola E, Schett G, Gerli R, et al. Clinical, radiographic and immunogenic effects after 1 year of tocilizumab-based treatment strategies in rheumatoid arthritis: the ACT-RAY study. Ann Rheum Dis. 2014;73:803-9 pubmed publisher
|
Westerhout J, van den Berg D, Hartman R, Danhof M, de Lange E. Prediction of methotrexate CNS distribution in different species - influence of disease conditions. Eur J Pharm Sci. 2014;57:11-24 pubmed publisher
|
Sadasivam N, Johnson R, Owen R. Resolution of methotrexate-induced Epstein-Barr virus-associated mucocutaneous ulcer. Br J Haematol. 2014;165:584 pubmed publisher
|
Kume K, Amano K, Yamada S, Kanazawa T, Ohta H, Hatta K, et al. The effect of tocilizumab on bone mineral density in patients with methotrexate-resistant active rheumatoid arthritis. Rheumatology (Oxford). 2014;53:900-3 pubmed publisher
|
Yamanaka H, Ishiguro N, Takeuchi T, Miyasaka N, Mukai M, Matsubara T, et al. Recovery of clinical but not radiographic outcomes by the delayed addition of adalimumab to methotrexate-treated Japanese patients with early rheumatoid arthritis: 52-week results of the HOPEFUL-1 trial. Rheumatology (Oxford). 2014;53:904-13 pubmed publisher
|
Ram R, Yeshurun M, Vidal L, Shpilberg O, Gafter Gvili A. Mycophenolate mofetil vs. methotrexate for the prevention of graft-versus-host-disease--systematic review and meta-analysis. Leuk Res. 2014;38:352-60 pubmed publisher
|
Melachuri S, Gandrud L, Bostrom B. The association between fasting hypoglycemia and methylated mercaptopurine metabolites in children with acute lymphoblastic leukemia. Pediatr Blood Cancer. 2014;61:1003-6 pubmed publisher
|
Lee M, Lin R, Lai M. Increased risk of diabetes mellitus in relation to the severity of psoriasis, concomitant medication, and comorbidity: a nationwide population-based cohort study. J Am Acad Dermatol. 2014;70:691-698 pubmed publisher
|
Cao X, Li J, Zhang W, Duan M, Shen T, Zhou D. Patients with primary diffuse large B-cell lymphoma of female genital tract have high risk of central nervous system relapse. Ann Hematol. 2014;93:1001-5 pubmed publisher
|
Ikebuchi R, Konnai S, Okagawa T, Yokoyama K, Nakajima C, Suzuki Y, et al. Influence of PD-L1 cross-linking on cell death in PD-L1-expressing cell lines and bovine lymphocytes. Immunology. 2014;142:551-61 pubmed publisher
|
Ota H, Koyama N, Nakamura A, Matsuda M, Yamamoto Y, Tomoda K, et al. [Case report; a case of methotrexate-associated lymphoproliferative disorders caused with multiple lung nodules]. Nihon Naika Gakkai Zasshi. 2013;102:2676-8 pubmed
|
Komagata Y. [Serious organ damage and intractable clinical conditions in rheumatic and connective tissue disease--progress in pathophysiology and treatment. Topics: II. Clinical conditions special attention needed to be paid to; 4. Macrophage activating syndrome. Nihon Naika Gakkai Zasshi. 2013;102:2639-44 pubmed
|
Kaneko J, Gozu K, Aoyagi H, Matsui T, Yoshida T, Hasegawa K, et al. [A case of iatrogenic immunodeficiency-associated lymphoproliferative disease in a patient treated with methotrexate for rheumatoid arthritis for 9 consecutive years, which Showed natural remission after discontinuation of MTX therapy]. Gan To Kagaku Ryoho. 2013;40:2454-6 pubmed
|
Fellows M, McDermott A, Clare K, Doherty A, Aardema M. The spectral karyotype of L5178Y TK⁺/⁻ mouse lymphoma cells clone 3.7.2C and factors affecting mutant frequency at the thymidine kinase (tk) locus in the microtitre mouse lymphoma assay. Environ Mol Mutagen. 2014;55:35-42 pubmed publisher
|
Perez Delboy A, Wright J. Surgical management of placenta accreta: to leave or remove the placenta?. BJOG. 2014;121:163-9; discussion 169-70 pubmed publisher
|
Fisher P. 50 years ago in the Journal of Pediatrics: central nervous system complications of children with acute leukemia: an evaluation of treatment methods. J Pediatr. 2014;164:33 pubmed publisher
|
Duffner P, ARMSTRONG F, Chen L, Helton K, Brecher M, Bell B, et al. Neurocognitive and neuroradiologic central nervous system late effects in children treated on Pediatric Oncology Group (POG) P9605 (standard risk) and P9201 (lesser risk) acute lymphoblastic leukemia protocols (ACCL0131): a methotrexate consequence? . J Pediatr Hematol Oncol. 2014;36:8-15 pubmed publisher
|
Nwanyanwu K, Lim J. Smudge in my vision. JAMA Ophthalmol. 2013;131:1637-8 pubmed publisher
|
Pouw M, Krieckaert C, Nurmohamed M, van der Kleij D, Aarden L, Rispens T, et al. Key findings towards optimising adalimumab treatment: the concentration-effect curve. Ann Rheum Dis. 2015;74:513-8 pubmed publisher
|
Shea B. Folic acid or folinic acid for reducing side effects of methotrexate for people with rheumatoid arthritis. J Evid Based Med. 2013;6:202-3 pubmed publisher
|
Vu Hoang P, Ambroise J, Dang Chi V, Dekairelle A, Dupont S, Huynh N, et al. Comparison of long-term outcome between white and Vietnamese children treated for acute lymphoblastic leukemia according to the FRALLE 2000 protocol. J Pediatr Hematol Oncol. 2014;36:534-40 pubmed publisher
|
Hashkes P, Becker M, Cabral D, Laxer R, Paller A, Rabinovich C, et al. Methotrexate: new uses for an old drug. J Pediatr. 2014;164:231-6 pubmed publisher
|
Aga A, Lie E, Uhlig T, Olsen I, Wierød A, Kalstad S, et al. Time trends in disease activity, response and remission rates in rheumatoid arthritis during the past decade: results from the NOR-DMARD study 2000-2010. Ann Rheum Dis. 2015;74:381-8 pubmed publisher
|
Tamilselvi E, Haripriya D, Hemamalini M, Pushpa G, Swapna S. Association of disease severity with IL-1 levels in methotrexate-treated psoriasis patients. Scand J Immunol. 2013;78:545-53 pubmed publisher
|
Dassopoulos T, Sultan S, Falck Ytter Y, Inadomi J, Hanauer S. American Gastroenterological Association Institute technical review on the use of thiopurines, methotrexate, and anti-TNF-α biologic drugs for the induction and maintenance of remission in inflammatory Crohn's disease. Gastroenterology. 2013;145:1464-78.e1-5 pubmed publisher
|
Terdiman J, Gruss C, Heidelbaugh J, Sultan S, Falck Ytter Y. American Gastroenterological Association Institute guideline on the use of thiopurines, methotrexate, and anti-TNF-α biologic drugs for the induction and maintenance of remission in inflammatory Crohn's disease. Gastroenterology. 2013;145:1459-63 pubmed publisher
|
Nagai Y, Minami T, Itami Y, Kobayashi Y, Shimizu N, Yamamoto Y, et al. [A case of a nonseminomatous germ cell tumor responding to MEA therapy]. Hinyokika Kiyo. 2013;59:693-7 pubmed
|
Naidu A, Kessler H, Pavelka M. Epstein-Barr virus-positive oral ulceration simulating Hodgkin lymphoma in a patient treated with methotrexate: case report and review of the literature. J Oral Maxillofac Surg. 2014;72:724-9 pubmed publisher
|
Sheen Y, Sheen Y, Sheu H, Sheen M. Bowen disease of the vulva successfully treated with intraarterial infusion chemotherapy. J Am Acad Dermatol. 2013;69:e305-6 pubmed publisher
|
Yazici Y, Bata Y. Parenteral methotrexate for the treatment of rheumatoid arthritis. Bull Hosp Jt Dis (2013). 2013;71 Suppl 1:46-8 pubmed
|
Mease P. Methotrexate in psoriatic arthritis. Bull Hosp Jt Dis (2013). 2013;71 Suppl 1:S41-5 pubmed
|
Ruderman E. The role of concomitant methotrexate in biologic therapy for rheumatoid arthritis. Bull Hosp Jt Dis (2013). 2013;71 Suppl 1:S29-32 pubmed
|
Castrejón I, Gibson K, Pincus T. Efficacy and safety of methotrexate in combination with other non-biologic disease-modifying antirheumatic drugs (DMARDs) in treatment of rheumatoid arthritis. Bull Hosp Jt Dis (2013). 2013;71 Suppl 1:S20-8 pubmed
|
Pincus T, Gibson K, Castrejón I. Update on methotrexate as the anchor drug for rheumatoid arthritis. Bull Hosp Jt Dis (2013). 2013;71 Suppl 1:S9-19 pubmed
|
Chan E, Cronstein B. Mechanisms of action of methotrexate. Bull Hosp Jt Dis (2013). 2013;71 Suppl 1:S5-8 pubmed
|
Hugh J, Van Voorhees A, Nijhawan R, Bagel J, Lebwohl M, Blauvelt A, et al. From the Medical Board of the National Psoriasis Foundation: The risk of cardiovascular disease in individuals with psoriasis and the potential impact of current therapies. J Am Acad Dermatol. 2014;70:168-77 pubmed publisher
|
Kirwan J, Boers M. Biological treatment in rheumatoid arthritis: when to stop?. Lancet. 2014;383:288-9 pubmed publisher
|
Smolen J, Emery P, Fleischmann R, van Vollenhoven R, Pavelka K, Durez P, et al. Adjustment of therapy in rheumatoid arthritis on the basis of achievement of stable low disease activity with adalimumab plus methotrexate or methotrexate alone: the randomised controlled OPTIMA trial. Lancet. 2014;383:321-32 pubmed publisher
|
de Rotte M, de Jong P, Pluijm S, Calasan M, Barendregt P, Van Zeben D, et al. Association of low baseline levels of erythrocyte folate with treatment nonresponse at three months in rheumatoid arthritis patients receiving methotrexate. Arthritis Rheum. 2013;65:2803-13 pubmed publisher
|
Xu W, Zhang L, Chen X, Pan B, Mao J, Song H, et al. Serum creatinine and creatinine clearance for predicting plasma methotrexate concentrations after high-dose methotrexate chemotherapy for the treatment for childhood lymphoblastic malignancies. Cancer Chemother Pharmacol. 2014;73:79-86 pubmed publisher
|
Tedeschi P, Markert E, Gounder M, Lin H, Dvorzhinski D, Dolfi S, et al. Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells. Cell Death Dis. 2013;4:e877 pubmed publisher
|
Chen S, Fahmi N, Bhattacharya C, Wang L, Jin Y, Benkovic S, et al. Fluorescent biphenyl derivatives of phenylalanine suitable for protein modification. Biochemistry. 2013;52:8580-9 pubmed publisher
|
Krüger K. [Rheumatoid arthritis: lower work loss during treatment with biologicals?--Modern treatment principles reduce work loss in rheumatoid arthritis]. Dtsch Med Wochenschr. 2013;138:2236 pubmed publisher
|
Saw V. Immunotherapy for corneal inflammatory disorders: stepping up and down the ladder. Br J Ophthalmol. 2013;97:1364-7 pubmed publisher
|
Verazza S, Negro G, Marafon D, Consolaro A, Martini A, Ravelli A. Possible discontinuation of therapies after clinical remission in juvenile idiopathic arthritis. Clin Exp Rheumatol. 2013;31:S98-101; quiz S102-7 pubmed
|
Cohen I, Wolff J. How long can folinic acid rescue be delayed after high-dose methotrexate without toxicity?. Pediatr Blood Cancer. 2014;61:7-10 pubmed publisher
|
Cohen I. Challenging the clinical relevance of folinic acid over rescue after high dose methotrexate (HDMTX). Med Hypotheses. 2013;81:942-7 pubmed publisher
|
Sumi T. [MTX associated lymphoproliferative disorder]. Nihon Jibiinkoka Gakkai Kaiho. 2013;116:734-5 pubmed
|
Niedzielska E, Wecławek Tompol J, Matkowska Kocjan A, Chybicka A. The influence of genetic RFC1, MS and MTHFR polymorphisms on the risk of acute lymphoblastic leukemia relapse in children and the adverse effects of methotrexate. Adv Clin Exp Med. 2013;22:579-84 pubmed
|
Oberpichler Schwenk H. [Rheumatoid arthritis: what to do if methotrexate fails?]. Med Monatsschr Pharm. 2013;36:279 pubmed
|
Nejković L, Pazin V, Filimonovic D. Cesarean section scar pregnancy treatment--case report. Clin Exp Obstet Gynecol. 2013;40:304-6 pubmed
|
Gong W, Li X, Ren H, Han C, Li Y, Wu Z. Superselective uterine arterial embolization combined with transcatheter intra-arterial methotrexate infusion in 40 cases with fallopian tube ectopic pregnancy. Clin Exp Obstet Gynecol. 2013;40:222-6 pubmed
|
Horokhovs kyĭ I, Ieshchenko I, Bovt V, Ieshchenko V, Iurchuk I. [Functional state of the ileum, cationic peptids and zinc content in the Paneth cells of the rats following lincomycin, indomethacin and methotrexate andministration]. Fiziol Zh. 2013;59:78-88 pubmed
|
Hazra S, Choudhury A, Asaduzzaman A, Paul H. Adverse outcome of methotrexate and mini pulse betamethasone in the treatment of lichen planus. Bangladesh Med Res Counc Bull. 2013;39:22-7 pubmed
|
Bezborodova O, Nemtsova E, Venediktova I, Iakubovskaia R, Aleksandrova L, Kovalenko A. [Experimental study of remaxol as a drug for supportive therapy in traditional and high-dose treatment of tumors]. Eksp Klin Farmakol. 2013;76:18-22 pubmed
|
Aouinti I, Gaïes E, Trabelsi S, Salouage I, Jebabli N, Charfi R, et al. Delayed elimination of methotrexate in a patient receiving ciprofloxacin. Therapie. 2013;68:175-7 pubmed publisher
|
Solomon D, Curtis J, Saag K, Lii J, Chen L, Harrold L, et al. Cardiovascular risk in rheumatoid arthritis: comparing TNF-α blockade with nonbiologic DMARDs. Am J Med. 2013;126:730.e9-730.e17 pubmed publisher
|
Hershko H. [A case of a preventable death]. Harefuah. 2013;152:365-6 pubmed
|
Cremers J, Drent M, Bast A, Shigemitsu H, Baughman R, Valeyre D, et al. Multinational evidence-based World Association of Sarcoidosis and Other Granulomatous Disorders recommendations for the use of methotrexate in sarcoidosis: integrating systematic literature research and expert opinion of sarcoidologists worldwide. Curr Opin Pulm Med. 2013;19:545-61 pubmed publisher
|
Weinblatt M. Methotrexate in rheumatoid arthritis: a quarter century of development. Trans Am Clin Climatol Assoc. 2013;124:16-25 pubmed
|
Katayama K, Nishino T, Takahashi Y, Tanaka T, Okitsu H, Okitsu N. [Approximately four years of survival benefits for a case of gastric cancer postoperative carcinomatous peritonitis by combined modality therapy]. Gan To Kagaku Ryoho. 2013;40:655-8 pubmed
|
Dogra S, Mahajan R. Systemic methotrexate therapy for psoriasis: past, present and future. Clin Exp Dermatol. 2013;38:573-88 pubmed publisher
|
. Fatal methotrexate overdose. Prescrire Int. 2013;22:126 pubmed
|
. Weekly oral methotrexate therapy: raise awareness of fatal dosing errors. Prescrire Int. 2013;22:126 pubmed
|
Kuleva S. [Delayed elimination of methotrexate after high-dose infusion]. Vopr Onkol. 2013;59:126-31 pubmed
|
Kalinina O, Kolotova E, Panfilova T, Shtil A, Frolov B. [The natural triterpenoid miliacin prevents methotrexate-induced oxidative stress and normalizes the expression of genes encoding the cytochrome P-450 2E1 isoform and glutathione reductase in the liver]. Patol Fiziol Eksp Ter. 2013;:70-4 pubmed
|
Begas E, Papandreou C, Tsakalof A, Daliani D, Papatsibas G, Asprodini E. Simple and reliable HPLC method for the monitoring of methotrexate in osteosarcoma patients. J Chromatogr Sci. 2014;52:590-5 pubmed publisher
|
Sáez Ayala M, Montenegro M, Sánchez del Campo L, Fernández Pérez M, Chazarra S, Freter R, et al. Directed phenotype switching as an effective antimelanoma strategy. Cancer Cell. 2013;24:105-19 pubmed publisher
|
Neuberg D, Arceci R. When "rare" is no excuse for progress. Blood. 2013;121:4970-2 pubmed publisher
|
McNeil C. Preventing graft-versus-host disease: transplanters glimpse hope beyond immunosuppressants. J Natl Cancer Inst. 2013;105:922-3 pubmed publisher
|
. Conventional triple therapy as good as etanercept for uncontrolled rheumatoid arthritis. BMJ. 2013;346:f3846 pubmed publisher
|
Kasai Yoshida E, Ogihara M, Ozawa M, Nozaki T, Morino M, Manabe A, et al. Temporal lobe epilepsy with hippocampal sclerosis in acute lymphoblastic leukemia. Pediatrics. 2013;132:e252-6 pubmed publisher
|
Marchetti M, Greer K. Pityriasis rubra pilaris treated with methotrexate resolving with an erythema gyratum repens-like appearance. J Am Acad Dermatol. 2013;69:e32-3 pubmed publisher
|
Sita Lumsden A, Medani H, Fisher R, Harvey R, Short D, Sebire N, et al. Uterine artery pulsatility index improves prediction of methotrexate resistance in women with gestational trophoblastic neoplasia with FIGO score 5-6. BJOG. 2013;120:1012-5 pubmed publisher
|
Bathon J, McMahon D. Making rational treatment decisions in rheumatoid arthritis when methotrexate fails. N Engl J Med. 2013;369:384-5 pubmed publisher
|
O Dell J, Mikuls T, Taylor T, Ahluwalia V, Brophy M, Warren S, et al. Therapies for active rheumatoid arthritis after methotrexate failure. N Engl J Med. 2013;369:307-18 pubmed publisher
|
Hossain D. Using methotrexate to treat patients with ENL unresponsive to steroids and clofazimine: a report on 9 patients. Lepr Rev. 2013;84:105-12 pubmed
|
Ochi N, Yamane H, Yamagishi T, Monobe Y, Takigawa N. Methotrexate-induced lymphoproliferative disease: Epstein-Barr virus-associated lymphomatoid granulomatosis. J Clin Oncol. 2013;31:e348-50 pubmed publisher
|
Waimann C, Marengo M, de Achaval S, Cox V, Garcia Gonzalez A, Reveille J, et al. Electronic monitoring of oral therapies in ethnically diverse and economically disadvantaged patients with rheumatoid arthritis: consequences of low adherence. Arthritis Rheum. 2013;65:1421-9 pubmed publisher
|
Hung C, Wu B. Palmoplantar pustulosis presenting with chest pain. Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome. JAMA Dermatol. 2013;149:475-80 pubmed publisher
|
Gollard R, Selco S. Irreversible myelopathy associated with nelaribine in T-cell acute lymphoblastic leukemia. J Clin Oncol. 2013;31:e327-31 pubmed publisher
|
Gelfand J, Wang S, Takeshita J, Robertson A, Krueger G, Callis Duffin K, et al. Using Hawthorne effects to improve adherence in clinical practice: lessons from clinical trials--reply. JAMA Dermatol. 2013;149:491 pubmed publisher
|
Davis S, Feldman S. Using Hawthorne effects to improve adherence in clinical practice: lessons from clinical trials. JAMA Dermatol. 2013;149:490-1 pubmed publisher
|
Arcinue C, Hochberg F, Neumann R, Foster C. Diagnostic criteria for primary ocular lymphoma. Ophthalmology. 2013;120:646-646.e2 pubmed publisher
|
Burmester G, Benda B, Gruben D, Bradley J, Mebus C. Tofacitinib for rheumatoid arthritis - Authors' reply. Lancet. 2013;381:1812-3 pubmed publisher
|
Alba M, Flores Suarez L. Seven clinical conundrums in the treatment of ANCA-associated vasculitis. Clin Exp Rheumatol. 2013;31:S74-83 pubmed
|
Kadakia A, Rajan S, Abughosh S, Du X, Johnson M. CMF-regimen preferred as first-course chemotherapy for older and sicker women with breast cancer: Findings from a SEER-Medicare-based population study. Am J Clin Oncol. 2015;38:165-73 pubmed publisher
|