This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Methotrexate
catalog :
M4010
citations: 342
Reference
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Figueiró F, de Oliveira C, Rockenbach L, Mendes F, Bergamin L, Jandrey E, et al. Pharmacological Improvement and Preclinical Evaluation of Methotrexate-Loaded Lipid-Core Nanocapsules in a Glioblastoma Model. J Biomed Nanotechnol. 2015;11:1808-18 pubmed
Oktaria S, Corde S, Lerch M, Konstantinov K, Rosenfeld A, Tehei M. Indirect radio-chemo-beta therapy: a targeted approach to increase biological efficiency of x-rays based on energy. Phys Med Biol. 2015;60:7847-59 pubmed publisher
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Liu Y, Cui Y, Chen Y, Gao X, Su Y, Cui L. Effects of dexamethasone, celecoxib, and methotrexate on the histology and metabolism of bone tissue in healthy Sprague Dawley rats. Clin Interv Aging. 2015;10:1245-53 pubmed publisher
Klećkowska Nawrot J, Chęć A, Goździewska Harłajczuk K, Nowaczyk R, Barszcz K. Light and electron microscopic studies of the Harderian gland in Bilgorajska goose (Anser anser). Acta Biol Hung. 2015;66:249-57 pubmed publisher
Godley B, Kraft E, Giannos S, Zhao Z, Haag A, Wen J. Photokinetic Drug Delivery: Light-Enhanced Permeation in an In Vitro Eye Model. J Ocul Pharmacol Ther. 2015;31:650-7 pubmed publisher
Vermaak E, Tansley S, McHugh N. The evidence for immunotherapy in dermatomyositis and polymyositis: a systematic review. Clin Rheumatol. 2015;34:2089-95 pubmed publisher
Quartararo C, Reznik E, deCarvalho A, Mikkelsen T, Stockwell B. High-Throughput Screening of Patient-Derived Cultures Reveals Potential for Precision Medicine in Glioblastoma. ACS Med Chem Lett. 2015;6:948-52 pubmed publisher
Wei Y, Sun X, Hua M, Tan W, Wang F, Zhang M. Inhibitory Effect of a Novel Antirheumatic Drug T-614 on the IL-6-Induced RANKL/OPG, IL-17, and MMP-3 Expression in Synovial Fibroblasts from Rheumatoid Arthritis Patients. Biomed Res Int. 2015;2015:214683 pubmed publisher
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Maher H, Ragab M, El Kimary E. Chemometrics-assisted Spectrofluorimetric Determination of Two Co-administered Drugs of Major Interaction, Methotrexate and Aspirin, in Human Urine Following Acid-induced Hydrolysis. Comb Chem High Throughput Screen. 2015;18:723-34 pubmed
Nakamura H, Yamashita N, Kanamaru Y, Tachibana T, Sekino Y, Chen S, et al. Quantitative analysis of intraneuronal transport in human iPS neurons. J Pharmacol Sci. 2015;128:170-8 pubmed publisher
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Park J, Jang J, Choi J, Kang M, Woo Y, Seong Y, et al. DC-Based Immunotherapy Combined with Low-Dose Methotrexate Effective in the Treatment of Advanced CIA in Mice. J Immunol Res. 2015;2015:834085 pubmed publisher
Tag H. Hepatoprotective effect of mulberry (Morus nigra) leaves extract against methotrexate induced hepatotoxicity in male albino rat. BMC Complement Altern Med. 2015;15:252 pubmed publisher
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Ferreira M, Chaves L, Lima S, Reis S. Optimization of nanostructured lipid carriers loaded with methotrexate: A tool for inflammatory and cancer therapy. Int J Pharm. 2015;492:65-72 pubmed publisher
Oyen D, Fenwick R, Stanfield R, Dyson H, Wright P. Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway. J Am Chem Soc. 2015;137:9459-68 pubmed publisher
Wahl S, Kennedy A, Wyatt B, Moore A, Pridgen D, Cherry A, et al. The role of folate metabolism in orofacial development and clefting. Dev Biol. 2015;405:108-22 pubmed publisher
Jeronimo M, Colombo M, Astrakianakis G, Hon C. A surface wipe sampling and LC-MS/MS method for the simultaneous detection of six antineoplastic drugs commonly handled by healthcare workers. Anal Bioanal Chem. 2015;407:7083-92 pubmed publisher
Thomas S, Fisher K, Snowden J, Danson S, Brown S, Zeidler M. Methotrexate Is a JAK/STAT Pathway Inhibitor. PLoS ONE. 2015;10:e0130078 pubmed publisher
de Thurah A, Nørgaard M, Stengaard Pedersen K. Methotrexate utilization in Rheumatoid arthritis. A register-based cohort-study of treatment re-starts after gabs of at least 90 days. Springerplus. 2015;4:227 pubmed publisher
Liu Y, Zhou S, Nissel J, Wu A, Lau H, Palmisano M. The pharmacokinetic effect of coadministration of apremilast and methotrexate in individuals with rheumatoid arthritis and psoriatic arthritis. Clin Pharmacol Drug Dev. 2014;3:456-465 pubmed
El Sheikh A, Morsy M, Abdalla A, Hamouda A, Alhaider I. Mechanisms of Thymoquinone Hepatorenal Protection in Methotrexate-Induced Toxicity in Rats. Mediators Inflamm. 2015;2015:859383 pubmed publisher
Loubet P, Kernéis S, Groh M, Loulergue P, Blanche P, Verger P, et al. Attitude, knowledge and factors associated with influenza and pneumococcal vaccine uptake in a large cohort of patients with secondary immune deficiency. Vaccine. 2015;33:3703-8 pubmed publisher
Mori F, Sacconi A, Canu V, Ganci F, Novello M, Anelli V, et al. miR-181c associates with tumor relapse of high grade osteosarcoma. Oncotarget. 2015;6:13946-61 pubmed
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Chernobrovkin A, Marin Vicente C, Visa N, Zubarev R. Functional Identification of Target by Expression Proteomics (FITExP) reveals protein targets and highlights mechanisms of action of small molecule drugs. Sci Rep. 2015;5:11176 pubmed publisher
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Li Z, Zhang F, Pan L, Zhu X, Zhang Z. Preparation and characterization of injectable Mitoxantrone poly (lactic acid)/fullerene implants for in vivo chemo-photodynamic therapy. J Photochem Photobiol B. 2015;149:51-7 pubmed publisher
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Chin C, Chin H, Chin C, Lai E, Ng S. Engineering selection stringency on expression vector for the production of recombinant human alpha1-antitrypsin using Chinese Hamster ovary cells. BMC Biotechnol. 2015;15:44 pubmed publisher
Chaturvedi P, Tulsyan S, Agarwal G, Lal P, Agrawal S, Mittal R, et al. Relationship of MTHFR and NQO1 Pharmacogenetics and Chemotherapy Clinical Outcomes in Breast Cancer Patients. Biochem Genet. 2015;53:211-22 pubmed publisher
Charolidi N, Schilling T, Eder C. Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice. PLoS ONE. 2015;10:e0128463 pubmed publisher
Lutterbeck C, Kern D, Machado Ã, Kümmerer K. Evaluation of the toxic effects of four anti-cancer drugs in plant bioassays and its potency for screening in the context of waste water reuse for irrigation. Chemosphere. 2015;135:403-10 pubmed publisher
Kim H, Lee S, Park K, Mun C, Park Y, Yoo K. Drug-loaded gold/iron/gold plasmonic nanoparticles for magnetic targeted chemo-photothermal treatment of rheumatoid arthritis. Biomaterials. 2015;61:95-102 pubmed publisher
Zhang Z, Zhang S, Jin B, Wu Y, Yang X, Yu B, et al. Ciclamilast ameliorates adjuvant-induced arthritis in a rat model. Biomed Res Int. 2015;2015:786104 pubmed publisher
Baser O, Ganguli A, Roy S, Xie L, Cifaldi M. Impact of Switching From an Initial Tumor Necrosis Factor Inhibitor on Health Care Resource Utilization and Costs Among Patients With Rheumatoid Arthritis. Clin Ther. 2015;37:1454-65 pubmed publisher
Li Z, Ou Yang Y, Liu Y, Wang Y, Zhu X, Zhang Z. Folic acid-conjugated TiO2-doped mesoporous carbonaceous nanocomposites loaded with Mitoxantrone HCl for chemo-photodynamic therapy. Photochem Photobiol Sci. 2015;14:1197-206 pubmed publisher
Landewé R, Smolen J, Florentinus S, Chen S, Guérette B, van der Heijde D. Existing joint erosions increase the risk of joint space narrowing independently of clinical synovitis in patients with early rheumatoid arthritis. Arthritis Res Ther. 2015;17:133 pubmed publisher
Ewees M, Abdelghany T, Abdel Aziz A, Abdel Bakky M. All-trans retinoic acid mitigates methotrexate-induced liver injury in rats; relevance of retinoic acid signaling pathway. Naunyn Schmiedebergs Arch Pharmacol. 2015;388:931-8 pubmed publisher
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Lee S, Park W, Park S, Shim S, Baek H, Yoo D, et al. Low baseline interleukin-17A levels are associated with better treatment response at 12 weeks to tocilizumab therapy in rheumatoid arthritis patients. J Immunol Res. 2015;2015:487230 pubmed publisher
Peters L, Karmon O, David Kadoch G, Hazan R, Yu T, Glickman M, et al. The protein quality control machinery regulates its misassembled proteasome subunits. PLoS Genet. 2015;11:e1005178 pubmed publisher
Curcio M, Blanco Fernández B, Costoya A, Concheiro A, Puoci F, Alvarez Lorenzo C. Glucose cryoprotectant affects glutathione-responsive antitumor drug release from polysaccharide nanoparticles. Eur J Pharm Biopharm. 2015;93:281-92 pubmed publisher
Shen Y, Yang J, Zhao J, Xiao C, Xu C, Xiang Y. The switch from ER stress-induced apoptosis to autophagy via ROS-mediated JNK/p62 signals: A survival mechanism in methotrexate-resistant choriocarcinoma cells. Exp Cell Res. 2015;334:207-18 pubmed publisher
Ferrando Climent L, Cruz Morató C, Marco Urrea E, Vicent T, Sarrà M, Rodriguez Mozaz S, et al. Non conventional biological treatment based on Trametes versicolor for the elimination of recalcitrant anticancer drugs in hospital wastewater. Chemosphere. 2015;136:9-19 pubmed publisher
Fikry E, Safar M, Hasan W, Fawzy H, El Denshary E. Bone Marrow and Adipose-Derived Mesenchymal Stem Cells Alleviate Methotrexate-Induced Pulmonary Fibrosis in Rat: Comparison with Dexamethasone. J Biochem Mol Toxicol. 2015;29:321-9 pubmed publisher
Liu Y, Lv J, Yang B, Liu F, Tian Z, Cai Y, et al. Lycium barbarum polysaccharide attenuates type II collagen-induced arthritis in mice. Int J Biol Macromol. 2015;78:318-23 pubmed publisher
Tang X, Chen J, Fang J, Sun X, Qin M, Li J, et al. Similar outcomes of allogeneic hematopoietic cell transplantation from unrelated donor and umbilical cord blood vs. sibling donor for pediatric acute myeloid leukemia: Multicenter experience in China. Pediatr Transplant. 2015;19:413-21 pubmed publisher
Huber S, Wege A, Bernhardt G, Buschauer A, Brockhoff G. Topotecan-induced ABCG2 expression in MCF-7 cells is associated with decreased CD24 and EpCAM expression and a loss of tumorigenicity. Cytometry A. 2015;87:707-16 pubmed publisher
Tian D, Jia W, Liu X, Wang D, Liu J, Dong J, et al. Methylation and its role in the disposition of tanshinol, a cardiovascular carboxylic catechol from Salvia miltiorrhiza roots (Danshen). Acta Pharmacol Sin. 2015;36:627-43 pubmed publisher
Scarselli A, Di Cesare S, Capponi C, Cascioli S, Romiti M, Di Matteo G, et al. Longitudinal Evaluation of Immune Reconstitution and B-cell Function After Hematopoietic Cell Transplantation for Primary Immunodeficiency. J Clin Immunol. 2015;35:373-83 pubmed publisher
Smolen J, Weinblatt M, van der Heijde D, Rigby W, van Vollenhoven R, Bingham C, et al. Efficacy and safety of tabalumab, an anti-B-cell-activating factor monoclonal antibody, in patients with rheumatoid arthritis who had an inadequate response to methotrexate therapy: results from a phase III multicentre, randomised, double-blind study. Ann Rheum Dis. 2015;74:1567-70 pubmed publisher
Kingsbury S, Tharmanathan P, Arden N, Batley M, Birrell F, Cocks K, et al. Pain reduction with oral methotrexate in knee osteoarthritis, a pragmatic phase iii trial of treatment effectiveness (PROMOTE): study protocol for a randomized controlled trial. Trials. 2015;16:77 pubmed publisher
Reinhart D, Damjanovic L, Kaisermayer C, Kunert R. Benchmarking of commercially available CHO cell culture media for antibody production. Appl Microbiol Biotechnol. 2015;99:4645-57 pubmed publisher
Narawa T, Yano T, Itoh T. Stereoselective recognition of amethopterin enantiomers by the rat proton-coupled folate transporter. Biol Pharm Bull. 2015;38:545-51 pubmed publisher
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Elliott T, Hudspith B, Rayment N, Prescott N, Petrovska L, Hermon Taylor J, et al. Defective macrophage handling of Escherichia coli in Crohn's disease. J Gastroenterol Hepatol. 2015;30:1265-74 pubmed publisher
Kay M, Hojati Z, Heidari M, Bazi Z, Korbekandi H. Effects of disruption of the nucleotide pattern in CRID element and Kozak sequence of interferon β on mRNA stability and protein production. Autoimmunity. 2015;48:336-43 pubmed publisher
Lee C, Kokolus K, Leigh N, Capitano M, Hylander B, Repasky E. Defining immunological impact and therapeutic benefit of mild heating in a murine model of arthritis. PLoS ONE. 2015;10:e0120327 pubmed publisher
Shah E, Siegel C, Chong K, Melmed G. Patients with Crohn's Disease Are More Likely to Remain on Biologics than Immunomodulators: A Meta-Analysis of Treatment Durability. Dig Dis Sci. 2015;60:2408-18 pubmed publisher
Matson K, Shaffer C, Beck G, Simonsen K. Assessment of initial serum vancomycin trough concentrations and their association with initial empirical weight-based vancomycin dosing and development of nephrotoxicity in children: a multicenter retrospective study. Pharmacotherapy. 2015;35:337-43 pubmed publisher
Sugiyama A, Sun J, Ueda K, Furukawa S, Takeuchi T. Effect of methotrexate on cerebellar development in infant rats. J Vet Med Sci. 2015;77:789-97 pubmed publisher
Ho S, Wang T, Song Z, Yang Y. IgG Aggregation Mechanism for CHO Cell Lines Expressing Excess Heavy Chains. Mol Biotechnol. 2015;57:625-34 pubmed publisher
Neradil J, Pavlasova G, Srámek M, Kyr M, Veselska R, Sterba J. DHFR-mediated effects of methotrexate in medulloblastoma and osteosarcoma cells: the same outcome of treatment with different doses in sensitive cell lines. Oncol Rep. 2015;33:2169-75 pubmed publisher
Ha T, Kim Y, Lee G. Understanding of altered N-glycosylation-related gene expression in recombinant Chinese hamster ovary cells subjected to elevated ammonium concentration by digital mRNA counting. Biotechnol Bioeng. 2015;112:1583-93 pubmed publisher
Tyagi K, Upadhyaya P, Sarma S, Tamboli V, Sreelakshmi Y, Sharma R. High performance liquid chromatography coupled to mass spectrometry for profiling and quantitative analysis of folate monoglutamates in tomato. Food Chem. 2015;179:76-84 pubmed publisher
Inui Y, Matsuoka H, Yakushijin K, Okamura A, Shimada T, Yano S, et al. Methotrexate-associated lymphoproliferative disorders: management by watchful waiting and observation of early lymphocyte recovery after methotrexate withdrawal. Leuk Lymphoma. 2015;56:3045-51 pubmed publisher
Asada H, Tomiyasu H, Goto Koshino Y, Fujino Y, Ohno K, Tsujimoto H. Evaluation of the drug sensitivity and expression of 16 drug resistance-related genes in canine histiocytic sarcoma cell lines. J Vet Med Sci. 2015;77:677-84 pubmed publisher
MacDonald C, Piper R. Puromycin- and methotrexate-resistance cassettes and optimized Cre-recombinase expression plasmids for use in yeast. Yeast. 2015;32:423-38 pubmed publisher
Cavicchioli L, Zanetti R, Ferraresso S, Crossan C, Barry P, Boldrin M, et al. Expression of recipient cytomegalovirus in immunosuppressed and xenotransplanted Macaca fascicularis may be related to more severe gastrointestinal lesions. Xenotransplantation. 2015;22:135-43 pubmed publisher
Mancardi G, Sormani M, Gualandi F, Saiz A, Carreras E, Merelli E, et al. Autologous hematopoietic stem cell transplantation in multiple sclerosis: a phase II trial. Neurology. 2015;84:981-8 pubmed publisher
Bluett J, Riba Garcia I, Hollywood K, Verstappen S, Barton A, Unwin R. A HPLC-SRM-MS based method for the detection and quantification of methotrexate in urine at doses used in clinical practice for patients with rheumatological disease: a potential measure of adherence. Analyst. 2015;140:1981-7 pubmed publisher
Kwon H, Lee J, Jeong K, Jang D, Pak Y. Fatty acylated caveolin-2 is a substrate of insulin receptor tyrosine kinase for insulin receptor substrate-1-directed signaling activation. Biochim Biophys Acta. 2015;1853:1022-34 pubmed publisher
Saygin C, Uzunaslan D, Hatemi G. Currently Used Biologic Agents in the Management of Behcet's Syndrome. Curr Med Chem. 2015;22:1976-85 pubmed
Tang Q, Yang Y, Zhao M, Liang G, Wu H, Liu Q, et al. Mycophenolic acid upregulates miR-142-3P/5P and miR-146a in lupus CD4+T cells. Lupus. 2015;24:935-42 pubmed publisher
Misra R, Upadhyay M, Perumal V, Mohanty S. In vitro control release, cytotoxicity assessment and cellular uptake of methotrexate loaded liquid-crystalline folate nanocarrier. Biomed Pharmacother. 2015;69:102-10 pubmed publisher
Lee J, Noh C, Yim C, Jeong Y, Ahn S, Lee W, et al. Kinetics of the Absorption, Distribution, Metabolism, and Excretion of Lobeglitazone, a Novel Activator of Peroxisome Proliferator-Activated Receptor Gamma in Rats. J Pharm Sci. 2015;104:3049-59 pubmed publisher
Wu D, Wang Y, Sun Y, Ouyang N, Qian J. A simple, rapid and reliable liquid chromatography-mass spectrometry method for determination of methotrexate in human plasma and its application to therapeutic drug monitoring. Biomed Chromatogr. 2015;29:1197-202 pubmed publisher
Wang C, Mäkilä E, Kaasalainen M, Hagström M, Salonen J, Hirvonen J, et al. Dual-drug delivery by porous silicon nanoparticles for improved cellular uptake, sustained release, and combination therapy. Acta Biomater. 2015;16:206-14 pubmed publisher
Martín R, Sánchez B, Urdaci M, Langella P, Suárez J, Bermúdez Humarán L. Effect of iron on the probiotic properties of the vaginal isolate Lactobacillus jensenii CECT 4306. Microbiology. 2015;161:708-18 pubmed publisher
Emery P, Hammoudeh M, Combe B. Etanercept tapering in rheumatoid arthritis. N Engl J Med. 2015;372:489-90 pubmed publisher
Chng J, Wang T, Nian R, Lau A, Hoi K, Ho S, et al. Cleavage efficient 2A peptides for high level monoclonal antibody expression in CHO cells. MAbs. 2015;7:403-12 pubmed publisher
Wang J, Li G. Mechanisms of methotrexate resistance in osteosarcoma cell lines and strategies for overcoming this resistance. Oncol Lett. 2015;9:940-944 pubmed
Patel S, Kusano A, Truong A, Stelzer K, Laramore G. Fast neutron radiotherapy in the treatment of malignant pleural mesothelioma. Am J Clin Oncol. 2015;38:47-50 pubmed publisher
Tan Y, Ng Q, Jia Q, Kwang J, He F. A novel humanized antibody neutralizes H5N1 influenza virus via two different mechanisms. J Virol. 2015;89:3712-22 pubmed publisher
Aaltonen K, Joensuu J, Virkki L, Sokka T, Aronen P, Relas H, et al. Rates of serious infections and malignancies among patients with rheumatoid arthritis receiving either tumor necrosis factor inhibitor or rituximab therapy. J Rheumatol. 2015;42:372-8 pubmed publisher
Frank M, Hennenberg E, Eyking A, Runzi M, Gerken G, Scott P, et al. TLR signaling modulates side effects of anticancer therapy in the small intestine. J Immunol. 2015;194:1983-95 pubmed publisher
Jung E, Han K, Kwon H, Patnaik B, Kim W, Hur G, et al. Anti-inflammatory activity of sappanchalcone isolated from Caesalpinia sappan L. in a collagen-induced arthritis mouse model. Arch Pharm Res. 2015;38:973-83 pubmed publisher
Kozaki T, Tagashira M, Yamanishi K, Ellis B, Kayanoki T, Ooishi R, et al. Evaluation of drug-drug interaction between the novel cPLA2 inhibitor AK106-001616 and methotrexate in rheumatoid arthritis patients. Xenobiotica. 2015;45:615-24 pubmed publisher
Hu Y, Wang L, Wang L, Wu X, Wu X, Gu Y, et al. Preferential cytotoxicity of bortezomib toward highly malignant human liposarcoma cells via suppression of MDR1 expression and function. Toxicol Appl Pharmacol. 2015;283:1-8 pubmed publisher
Liu X, Kuriyan A, Amescua G. A painful red eye. JAMA Ophthalmol. 2015;133:95-6 pubmed publisher
Zhang W, Zhang Q, Tian X, Zhao H, Lu W, Zhen J, et al. Population pharmacokinetics of high-dose methotrexate after intravenous administration in Chinese osteosarcoma patients from a single institution. Chin Med J (Engl). 2015;128:111-8 pubmed publisher
Trendowski M, Wong V, Yu G, Fondy T. Enlargement and multinucleation of u937 leukemia and MCF7 breast carcinoma cells by antineoplastic agents to enhance sensitivity to low frequency ultrasound and to DNA-directed anticancer agents. Anticancer Res. 2015;35:65-76 pubmed
López Molina D, Chazarra S, How C, Pruidze N, Navarro Perán E, García Cánovas F, et al. Cinnamate of inulin as a vehicle for delivery of colonic drugs. Int J Pharm. 2015;479:96-102 pubmed publisher
Tanaka E, Inoue E, Hoshi D, Shimizu Y, Kobayashi A, Sugimoto N, et al. Cost-effectiveness of tocilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, versus methotrexate in patients with rheumatoid arthritis using real-world data from the IORRA observational cohort study. Mod Rheumatol. 2015;25:503-13 pubmed publisher
Yano K, Mita S, Morimoto K, Haraguchi T, Arakawa H, Yoshida M, et al. Multiple Linear Regression Analysis Indicates Association of P-Glycoprotein Substrate or Inhibitor Character with Bitterness Intensity, Measured with a Sensor. J Pharm Sci. 2015;104:2789-94 pubmed publisher
Revalde J, Li Y, Hawkins B, Rosengren R, Paxton J. Heterocyclic cyclohexanone monocarbonyl analogs of curcumin can inhibit the activity of ATP-binding cassette transporters in cancer multidrug resistance. Biochem Pharmacol. 2015;93:305-17 pubmed publisher
Meng X, Qi X, Guo H, Cai M, Li C, Zhu J, et al. Novel role for non-homologous end joining in the formation of double minutes in methotrexate-resistant colon cancer cells. J Med Genet. 2015;52:135-44 pubmed publisher
Panther D, Nino T, Macknet K, Macknet C. Eruptive keratoacanthomas as a complication of fractionated CO2 laser resurfacing and combination therapy with imiquimod and intralesional methotrexate. Dermatol Surg. 2015;41:172-5 pubmed publisher
Winocur G, Wojtowicz J, Tannock I. Memory loss in chemotherapy-treated rats is exacerbated in high-interference conditions and related to suppression of hippocampal neurogenesis. Behav Brain Res. 2015;281:239-44 pubmed publisher
Tawfik M. Combination of coenzyme Q10 with methotrexate suppresses Freund's complete adjuvant-induced synovial inflammation with reduced hepatotoxicity in rats: Effect on oxidative stress and inflammation. Int Immunopharmacol. 2015;24:80-7 pubmed publisher
Zhou F, Yu Y, Zhou X, Xian C. Methotrexate chemotherapy triggers touch-evoked pain and increased CGRP-positive sensory fibres in the tibial periosteum of young rats. Bone. 2015;73:24-31 pubmed publisher
Crowley J, Weinberg J, Wu J, Robertson A, Van Voorhees A. Treatment of nail psoriasis: best practice recommendations from the Medical Board of the National Psoriasis Foundation. JAMA Dermatol. 2015;151:87-94 pubmed publisher
Ieva R, Schrempp S, Opaliński L, Wollweber F, Höß P, Heißwolf A, et al. Mgr2 functions as lateral gatekeeper for preprotein sorting in the mitochondrial inner membrane. Mol Cell. 2014;56:641-52 pubmed publisher
Vishwanathan N, Yongky A, Johnson K, Fu H, Jacob N, Le H, et al. Global insights into the Chinese hamster and CHO cell transcriptomes. Biotechnol Bioeng. 2015;112:965-76 pubmed publisher
Nowak D, Liem N, Mossner M, Klaumünzer M, Papa R, Nowak V, et al. Variegated clonality and rapid emergence of new molecular lesions in xenografts of acute lymphoblastic leukemia are associated with drug resistance. Exp Hematol. 2015;43:32-43.e1-35 pubmed publisher
Sarker S, Kodali S, Weber F. A new meaning to butterflies in the stomach. Gastroenterology. 2015;148:e12-3 pubmed publisher
Pinto M, Moura C, Nunes C, Segundo M, Costa Lima S, Reis S. A new topical formulation for psoriasis: development of methotrexate-loaded nanostructured lipid carriers. Int J Pharm. 2014;477:519-26 pubmed publisher
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product information
Catalog Number :
M4010
Product Name :
Methotrexate
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
meets EP, USP testing specifications
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA