This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Methylphenidate hydrochloride
catalog :
M2892
citations: 82
Reference
You Z, Ding W, Doheny J, Shen S, Yang J, Yang L, et al. Methylphenidate and Morphine Combination Therapy in a Rat Model of Chronic Pain. Anesth Analg. 2020;130:518-524 pubmed publisher
Stagkourakis S, Dunevall J, Taleat Z, Ewing A, Broberger C. Dopamine Release Dynamics in the Tuberoinfundibular Dopamine System. J Neurosci. 2019;39:4009-4022 pubmed publisher
Hetzler B, McLester Davis L, Tenpas S. Methylphenidate and alcohol effects on flash-evoked potentials, body temperature, and behavior in Long-Evans rats. Alcohol. 2019;77:79-89 pubmed publisher
Guillem A, Martínez Lozada Z, Hernández Kelly L, López Bayghen E, López Bayghen B, Calleros O, et al. Methylphenidate Increases Glutamate Uptake in Bergmann Glial Cells. Neurochem Res. 2015;40:2317-24 pubmed publisher
Claussen C, Dafny N. Caudate neuronal recording in freely behaving animals following acute and chronic dose response methylphenidate exposure. Pharmacol Biochem Behav. 2015;136:21-30 pubmed publisher
Baskin B, Dwoskin L, Kantak K. Methylphenidate treatment beyond adolescence maintains increased cocaine self-administration in the spontaneously hypertensive rat model of attention deficit/hyperactivity disorder. Pharmacol Biochem Behav. 2015;131:51-6 pubmed publisher
Thanos P, Robison L, Steier J, Hwang Y, Cooper T, Swanson J, et al. A pharmacokinetic model of oral methylphenidate in the rat and effects on behavior. Pharmacol Biochem Behav. 2015;131:143-53 pubmed publisher
Urch T. [The pills are also effective in the dog]. MMW Fortschr Med. 2014;156:8 pubmed
Simchon Tenenbaum Y, Weizman A, Rehavi M. Alterations in brain neurotrophic and glial factors following early age chronic methylphenidate and cocaine administration. Behav Brain Res. 2015;282:125-32 pubmed publisher
Achterberg E, van Kerkhof L, Damsteegt R, Trezza V, Vanderschuren L. Methylphenidate and atomoxetine inhibit social play behavior through prefrontal and subcortical limbic mechanisms in rats. J Neurosci. 2015;35:161-9 pubmed publisher
Day J, Zienius K, Gehring K, GROSSHANS D, Taphoorn M, Grant R, et al. Interventions for preventing and ameliorating cognitive deficits in adults treated with cranial irradiation. Cochrane Database Syst Rev. 2014;:CD011335 pubmed publisher
Man K, Chan E, Coghill D, Douglas I, Ip P, Leung L, et al. Methylphenidate and the risk of trauma. Pediatrics. 2015;135:40-8 pubmed publisher
Wrenn C, Heitzer A, Roth A, Nawrocki L, Valdovinos M. Effects of clonidine and methylphenidate on motor activity in Fmr1 knockout mice. Neurosci Lett. 2015;585:109-13 pubmed publisher
Frolov A, Reyes Vasquez C, Dafny N. Behavioral and neuronal recording of the nucleus accumbens in adolescent rats following acute and repetitive exposure to methylphenidate. J Neurophysiol. 2015;113:369-79 pubmed publisher
Castellino S, Ullrich N, Whelen M, Lange B. Developing interventions for cancer-related cognitive dysfunction in childhood cancer survivors. J Natl Cancer Inst. 2014;106: pubmed publisher
Mori T, Uzawa N, Kazawa H, Watanabe H, Mochizuki A, Shibasaki M, et al. Differential substitution for the discriminative stimulus effects of 3,4-methylenedioxymethamphetamine and methylphenidate in rats. J Pharmacol Exp Ther. 2014;350:403-11 pubmed publisher
Sanefuji M, Yamashita H, Torisu H, Takada Y, Imanaga H, Matsunaga M, et al. Altered strategy in short-term memory for pictures in children with attention-deficit/hyperactivity disorder: a near-infrared spectroscopy study. Psychiatry Res. 2014;223:37-42 pubmed publisher
Jordan C, Harvey R, Baskin B, Dwoskin L, Kantak K. Cocaine-seeking behavior in a genetic model of attention-deficit/hyperactivity disorder following adolescent methylphenidate or atomoxetine treatments. Drug Alcohol Depend. 2014;140:25-32 pubmed publisher
Conklin H, Reddick W, Khan R. Comment on Smithson et al.'s review of stimulant medication usage to improve neurocognitive and learning outcomes in childhood brain tumour survivors. Eur J Cancer. 2014;50:1566-8 pubmed publisher
Smithson E, Phillips R, Harvey D, Morrall M. Response to letter that comments on published paper: The use of stimulant medication to improve neurocognitive and learning outcomes in children diagnosed with brain tumours: A systematic review. Eur J Cancer. 2014;50:1569-70 pubmed publisher
Feldman H, Reiff M. Clinical practice. Attention deficit-hyperactivity disorder in children and adolescents. N Engl J Med. 2014;370:838-46 pubmed publisher
Sharpe K. Medication: the smart-pill oversell. Nature. 2014;506:146-8 pubmed publisher
Ganelin Cohen E, Ashkenasi A. Disordered sleep in pediatric patients with attention deficit hyperactivity disorder: an overview. Isr Med Assoc J. 2013;15:705-9 pubmed
Reddick W, Taghipour D, Glass J, Ashford J, Xiong X, Wu S, et al. Prognostic factors that increase the risk for reduced white matter volumes and deficits in attention and learning for survivors of childhood cancers. Pediatr Blood Cancer. 2014;61:1074-9 pubmed publisher
Onishi E, Biagioli F, Safranek S. FPIN's Clinical Inquiries. Methylphenidate for management of fatigue in the palliative care setting. Am Fam Physician. 2014;89:124-7 pubmed
Amos A. Biased reporting of results in patients at ultra-high risk of psychosis. J Clin Psychiatry. 2013;74:1123 pubmed publisher
Ioannidis K, Serfontein J, Muller U. Bulimia nervosa patient diagnosed with previously unsuspected ADHD in adulthood: clinical case report, literature review, and diagnostic challenges. Int J Eat Disord. 2014;47:431-6 pubmed publisher
Fosi T, Lax Pericall M, Scott R, Neville B, Aylett S. Methylphenidate treatment of attention deficit hyperactivity disorder in young people with learning disability and difficult-to-treat epilepsy: evidence of clinical benefit. Epilepsia. 2013;54:2071-81 pubmed
Grizenko N, Cai E, Jolicoeur C, Ter Stepanian M, Joober R. Effects of methylphenidate on acute math performance in children with attention-deficit hyperactivity disorder. Can J Psychiatry. 2013;58:632-9 pubmed
Timimi S. Over-prescribing methylphenidate won't be cured by autism-style assessments. BMJ. 2013;347:f6622 pubmed publisher
McClure I. Author's reply to Timimi. BMJ. 2013;347:f6621 pubmed publisher
Reddy D. Current pharmacotherapy of attention deficit hyperactivity disorder. Drugs Today (Barc). 2013;49:647-65 pubmed publisher
Del Campo N, Fryer T, Hong Y, Smith R, Brichard L, Acosta Cabronero J, et al. A positron emission tomography study of nigro-striatal dopaminergic mechanisms underlying attention: implications for ADHD and its treatment. Brain. 2013;136:3252-70 pubmed publisher
Klein S, Ho V, Tazkarji B, Auten B. FPIN's clinical inquiries: Management of ADHD in preschool-aged children. Am Fam Physician. 2013;88:398-400 pubmed
McClure I. Prescribing methylphenidate for moderate ADHD. BMJ. 2013;347:f6216 pubmed publisher
Yilmaz S, Bilgic A. The possible effect of methylphenidate on kleptomania in a school-age girl with attention-deficit/hyperactivity disorder. Eur Child Adolesc Psychiatry. 2014;23:361-3 pubmed
Spencer T, Brown A, Seidman L, Valera E, Makris N, Lomedico A, et al. Effect of psychostimulants on brain structure and function in ADHD: a qualitative literature review of magnetic resonance imaging-based neuroimaging studies. J Clin Psychiatry. 2013;74:902-17 pubmed publisher
Gormez V, Avery B, Mann H. Switching from immediate release to sustained release methylphenidate in the treatment of children and adolescents with attention deficit/hyperactivity disorder. Eur Rev Med Pharmacol Sci. 2013;17:2345-9 pubmed
Childress A, Sallee F. The use of methylphenidate hydrochloride extended-release oral suspension for the treatment of ADHD. Expert Rev Neurother. 2013;13:979-88 pubmed publisher
. Methylphenidate: trismus. Prescrire Int. 2013;22:185 pubmed
Palmini A, Santos K. Santos et al. reply. Dev Med Child Neurol. 2013;55:967 pubmed publisher
Martelle S, Porrino L, Nader M. Effects of chronic methylphenidate in adolescence on later methylphenidate self-administration in rhesus monkeys. Behav Pharmacol. 2013;24:478-81 pubmed publisher
de Raaf P, van der Rijt C. Can you help me feel less exhausted all the time?. J Clin Oncol. 2013;31:3056-60 pubmed publisher
Smithson E, Phillips R, Harvey D, Morrall M. The use of stimulant medication to improve neurocognitive and learning outcomes in children diagnosed with brain tumours: a systematic review. Eur J Cancer. 2013;49:3029-40 pubmed publisher
Djalali S. [Not Available]. Praxis (Bern 1994). 2013;102:877-8 pubmed publisher
Panei P, Arcieri R. [ADHD register: post-marketing evaluation of the benefit-risk profile of drugs and promotion of the appropriateness]. Recenti Prog Med. 2013;104:254-61 pubmed publisher
Savulescu J. A liberal consequentialist approach to regulation of cognitive enhancers. Am J Bioeth. 2013;13:53-5 pubmed publisher
van der Eijk Y. Tobacco: prohibition, coffee shops, or discouragement?. Am J Bioeth. 2013;13:51-3 pubmed publisher
Flanigan J. An argument for permitting amphetamines and instant-release methylphenidate. Am J Bioeth. 2013;13:49-51 pubmed publisher
Brewer C, DeGrote H. Regulating methylphenidate: enhancing cognition and social inequality. Am J Bioeth. 2013;13:47-9 pubmed publisher
Faulmüller N, Maslen H, de Sio F. The indirect psychological costs of cognitive enhancement. Am J Bioeth. 2013;13:45-7 pubmed publisher
LaBuzetta J. Moving beyond methylphenidate and amphetamine: the ethics of a better "smart drug". Am J Bioeth. 2013;13:43-5 pubmed publisher
Forlini C, Racine E, Vollmann J, Schildmann J. How research on stakeholder perspectives can inform policy on cognitive enhancement. Am J Bioeth. 2013;13:41-3 pubmed publisher
Greely H. Some first steps toward responsible use of cognitive-enhancing drugs by the healthy. Am J Bioeth. 2013;13:39-41 pubmed publisher
Levy N. There may be costs to failing to enhance, as well as to enhancing. Am J Bioeth. 2013;13:38-9 pubmed publisher
Hall W, Partridge B, Lucke J. Constraints on regulatory options for putatively cognitive enhancing drugs. Am J Bioeth. 2013;13:35-7 pubmed publisher
Sandberg A. Enhancement policy and the value of information. Am J Bioeth. 2013;13:34-5 pubmed publisher
Dubljević V. Prohibition or coffee shops: regulation of amphetamine and methylphenidate for enhancement use by healthy adults. Am J Bioeth. 2013;13:23-33 pubmed publisher
Bachmann C, Manthey T, Kamp Becker I, Glaeske G, Hoffmann F. Psychopharmacological treatment in children and adolescents with autism spectrum disorders in Germany. Res Dev Disabil. 2013;34:2551-63 pubmed publisher
Brunklaus A, Dorris L, Zuberi S. The impact of methylphenidate on seizure frequency and severity in children with attention-deficit-hyperactivity disorder and difficult-to-treat epilepsies. Dev Med Child Neurol. 2013;55:966-7 pubmed publisher
Semeijn E, Kooij J, Comijs H, Michielsen M, Deeg D, Beekman A. Attention-deficit/hyperactivity disorder, physical health, and lifestyle in older adults. J Am Geriatr Soc. 2013;61:882-7 pubmed publisher
Stone P. Methylphenidate in the management of cancer-related fatigue. J Clin Oncol. 2013;31:2372-3 pubmed publisher
Bruera E, Yennurajalingam S, Palmer J, Perez Cruz P, Frisbee Hume S, Allo J, et al. Methylphenidate and/or a nursing telephone intervention for fatigue in patients with advanced cancer: a randomized, placebo-controlled, phase II trial. J Clin Oncol. 2013;31:2421-7 pubmed publisher
Ding K, Liu Y, Kang C, Liu R, Li X, Wan S. [Influential factors for methylphenidate treatment compliance in children with attention deficit hyperactivity disorder]. Zhongguo Dang Dai Er Ke Za Zhi. 2013;15:343-7 pubmed
Meisel V, Servera M, García Banda G, Cardo E, Moreno I. Neurofeedback and standard pharmacological intervention in ADHD: a randomized controlled trial with six-month follow-up. Biol Psychol. 2013;94:12-21 pubmed publisher
Stray L, Kristensen Ø, Lomeland M, Skorstad M, Stray T, Tønnessen F. Motor regulation problems and pain in adults diagnosed with ADHD. Behav Brain Funct. 2013;9:18 pubmed publisher
Heinrich H, Studer P, Moll G, Kratz O. Methylphenidate vs atomoxetine: personalized medicine in attention- deficit/hyperactivity disorder. JAMA Psychiatry. 2013;70:545 pubmed publisher
Somkuwar S, Darna M, Kantak K, Dwoskin L. Adolescence methylphenidate treatment in a rodent model of attention deficit/hyperactivity disorder: dopamine transporter function and cellular distribution in adulthood. Biochem Pharmacol. 2013;86:309-16 pubmed publisher
Shorer Z, Bachner Y, Guy T, Melzer I. Effect of single dose methylphenidate on walking and postural stability under single- and dual-task conditions in older adults--a double-blind randomized control trial. J Gerontol A Biol Sci Med Sci. 2013;68:1271-80 pubmed publisher
Czoty P, Martelle S, Gould R, Nader M. Effects of chronic methylphenidate on cocaine self-administration under a progressive-ratio schedule of reinforcement in rhesus monkeys. J Pharmacol Exp Ther. 2013;345:374-82 pubmed publisher
Groen Y, Tucha O, Wijers A, Althaus M. Processing of continuously provided punishment and reward in children with ADHD and the modulating effects of stimulant medication: an ERP study. PLoS ONE. 2013;8:e59240 pubmed publisher
Charach A, Carson P, Fox S, Ali M, Beckett J, Lim C. Interventions for preschool children at high risk for ADHD: a comparative effectiveness review. Pediatrics. 2013;131:e1584-604 pubmed publisher
Burgard D, Fuller R, Becker B, Ferrell R, Dinglasan Panlilio M. Potential trends in Attention Deficit Hyperactivity Disorder (ADHD) drug use on a college campus: wastewater analysis of amphetamine and ritalinic acid. Sci Total Environ. 2013;450-451:242-9 pubmed publisher
Sakakihara Y. More attention to ADHD. Dev Med Child Neurol. 2013;55:296 pubmed publisher
Santos K, Palmini A, Radziuk A, Rotert R, Bastos F, Booij L, et al. The impact of methylphenidate on seizure frequency and severity in children with attention-deficit-hyperactivity disorder and difficult-to-treat epilepsies. Dev Med Child Neurol. 2013;55:654-60 pubmed publisher
Van der Oord S, Ponsioen A, Geurts H, Ten Brink E, Prins P. A pilot study of the efficacy of a computerized executive functioning remediation training with game elements for children with ADHD in an outpatient setting: outcome on parent- and teacher-rated executive functioning and ADHD behavior. J Atten Disord. 2014;18:699-712 pubmed publisher
Peyre H, Speranza M, Cortese S, Wohl M, Purper Ouakil D. Do ADHD children with and without child behavior checklist-dysregulation profile have different clinical characteristics, cognitive features, and treatment outcomes?. J Atten Disord. 2015;19:63-71 pubmed publisher
McBurnett K, Starr H. OROS methylphenidate hydrochloride for adult patients with attention deficit/hyperactivity disorder. Expert Opin Pharmacother. 2011;12:315-24 pubmed publisher
Patrick K, Williard R, VanWert A, Dowd J, Oatis J, Middaugh L. Synthesis and pharmacology of ethylphenidate enantiomers: the human transesterification metabolite of methylphenidate and ethanol. J Med Chem. 2005;48:2876-81 pubmed
. Dexmethylphenidate--Novartis/Celgene. Focalin, D-MPH, D-methylphenidate hydrochloride, D-methylphenidate, dexmethylphenidate, dexmethylphenidate hydrochloride. Drugs R D. 2002;3:279-82 pubmed
Kuczenski R, Segal D. Locomotor effects of acute and repeated threshold doses of amphetamine and methylphenidate: relative roles of dopamine and norepinephrine. J Pharmacol Exp Ther. 2001;296:876-83 pubmed
Kraus M, Burch E. Methylphenidate hydrochloride as an antidepressant: controversy, case studies, and review. South Med J. 1992;85:985-91 pubmed
product information
Catalog Number :
M2892
Product Name :
Methylphenidate hydrochloride
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA