This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Mianserin hydrochloride
catalog :
M2525
citations: 47
Reference
Fossat P, Bacqué Cazenave J, De Deurwaerdère P, Cattaert D, Delbecque J. Serotonin, but not dopamine, controls the stress response and anxiety-like behavior in the crayfish Procambarus clarkii. J Exp Biol. 2015;218:2745-52 pubmed publisher
Olianas M, Dedoni S, Onali P. Antidepressants activate the lysophosphatidic acid receptor LPA(1) to induce insulin-like growth factor-I receptor transactivation, stimulation of ERK1/2 signaling and cell proliferation in CHO-K1 fibroblasts. Biochem Pharmacol. 2015;95:311-23 pubmed publisher
Podurgiel S, Milligan M, Yohn S, Purcell L, Contreras Mora H, Correa M, et al. Fluoxetine Administration Exacerbates Oral Tremor and Striatal Dopamine Depletion in a Rodent Pharmacological Model of Parkinsonism. Neuropsychopharmacology. 2015;40:2240-7 pubmed publisher
Okubo M, Murayama N, Miura J, Chiba Y, Yamazaki H. Effects of cytochrome P450 2D6 and 3A5 genotypes and possible coadministered medicines on the metabolic clearance of antidepressant mirtazapine in Japanese patients. Biochem Pharmacol. 2015;93:104-9 pubmed publisher
Dinesh N, Kaur P, Swamy K, Singh S. Mianserin, an antidepressant kills Leishmania donovani by depleting ergosterol levels. Exp Parasitol. 2014;144:84-90 pubmed publisher
Rajpurohit N, Aryal S, Khan M, Stys A, Stys T. Propafenone associated severe central nervous system and cardiovascular toxicity due to mirtazapine: a case of severe drug interaction. S D Med. 2014;67:137-9 pubmed
Yin J, Song J, Lei Y, Xu X, Chen J. Prokinetic effects of mirtazapine on gastrointestinal transit. Am J Physiol Gastrointest Liver Physiol. 2014;306:G796-801 pubmed publisher
Berling I, Isbister G. Mirtazapine overdose is unlikely to cause major toxicity. Clin Toxicol (Phila). 2014;52:20-4 pubmed publisher
Bognár Z, Vonyik G, Gazdag G. [Antidepressant treatment associated hyponatremia -- case report]. Neuropsychopharmacol Hung. 2013;15:177-80 pubmed
Holland J, Bhogle M. Sertraline and mirtazapine as geriatric antidepressants. Psychiatr Danub. 2013;25 Suppl 2:S286-90 pubmed
Liu X, Zhang G, Dong L, Wang X, Sun H, Shen J, et al. Repeated administration of mirtazapine attenuates oxaliplatin-induced mechanical allodynia and spinal NR2B up-regulation in rats. Neurochem Res. 2013;38:1973-9 pubmed publisher
Yosipovitch G, Bernhard J. Clinical practice. Chronic pruritus. N Engl J Med. 2013;368:1625-34 pubmed publisher
Theunissen E, Street D, Højer A, Vermeeren A, van Oers A, Ramaekers J. A randomized trial on the acute and steady-state effects of a new antidepressant, vortioxetine (Lu AA21004), on actual driving and cognition. Clin Pharmacol Ther. 2013;93:493-501 pubmed publisher
Banerjee S, Hellier J, Romeo R, Dewey M, Knapp M, Ballard C, et al. Study of the use of antidepressants for depression in dementia: the HTA-SADD trial--a multicentre, randomised, double-blind, placebo-controlled trial of the clinical effectiveness and cost-effectiveness of sertraline and mirtazapine. Health Technol Assess. 2013;17:1-166 pubmed publisher
Lozano R. Mirtazapine and ondansetron: a dual pharmacodynamic and pharmacokinetic interaction. Afr J Psychiatry (Johannesbg). 2013;16:56 pubmed
Rogóż Z. Effect of co-treatment with mirtazapine and risperidone in animal models of the positive symptoms of schizophrenia in mice. Pharmacol Rep. 2012;64:1567-72 pubmed
Rogóż Z, Kabziński M, Sadaj W, Rachwalska P, Gądek Michalska A. Effect of co-treatment with fluoxetine or mirtazapine and risperidone on the active behaviors and plasma corticosterone concentration in rats subjected to the forced swim test. Pharmacol Rep. 2012;64:1391-9 pubmed
Reed R, Fazel M, Goldring L. [Posttraumatic stress disorder]. Praxis (Bern 1994). 2013;102:45-8 pubmed publisher
Kreiss D, Coffman C, Fiacco N, Granger J, Helton B, Jackson J, et al. Ritualistic chewing behavior induced by mCPP in the rat is an animal model of obsessive compulsive disorder. Pharmacol Biochem Behav. 2013;104:119-24 pubmed publisher
Pae C. Comments on 'what is a rational antidepressant treatment for major depression in patients with Parkinson's disease?'. Psychiatry Clin Neurosci. 2013;67:65-6 pubmed publisher
Raghunath A. Gingival pain: an unusual side effect of ziprasidone. BMJ Case Rep. 2013;2013: pubmed publisher
Gulec M, Oral E, Dursun O, Yucel A, Hacimuftuoglu A, Akcay F, et al. Mirtazapine protects against cisplatin-induced oxidative stress and DNA damage in the rat brain. Psychiatry Clin Neurosci. 2013;67:50-8 pubmed publisher
Schilling C, Gilles M, Blum W, Daseking E, Colla M, Weber Hamann B, et al. Leptin plasma concentrations increase during antidepressant treatment with amitriptyline and mirtazapine, but not paroxetine and venlafaxine: leptin resistance mediated by antihistaminergic activity?. J Clin Psychopharmacol. 2013;33:99-103 pubmed publisher
Zuidersma M, Conradi H, van Melle J, Ormel J, De Jonge P. Depression treatment after myocardial infarction and long-term risk of subsequent cardiovascular events and mortality: a randomized controlled trial. J Psychosom Res. 2013;74:25-30 pubmed publisher
Sagdinc S, Sahinturk A. Molecular structure, FT-IR, FT-Raman, NMR studies and first order molecular hyperpolarizabilities by the DFT method of mirtazapine and its comparison with mianserin. Spectrochim Acta A Mol Biomol Spectrosc. 2013;104:222-34 pubmed publisher
Romeo R, Knapp M, Hellier J, Dewey M, Ballard C, Baldwin R, et al. Cost-effectiveness analyses for mirtazapine and sertraline in dementia: randomised controlled trial. Br J Psychiatry. 2013;202:121-8 pubmed publisher
Bilici M, Cayir K, Tekin S, Gundogdu C, Albayrak A, Suleyman B, et al. Effect of mirtazapine on MNNG-induced gastric adenocarcinoma in rats. Asian Pac J Cancer Prev. 2012;13:4897-900 pubmed
Avena Woods C, Hilas O. Antidepressant use in underweight older adults. Consult Pharm. 2012;27:868-70 pubmed publisher
Knud Larsen J. [Mirtazapine versus other antidepressive agents for depression]. Ugeskr Laeger. 2012;174:2864-6 pubmed
Sfair L, Gobetti C, Sangoi M, Lange A, Steppe M, Schapoval E. Micellar electrokinetic chromatographic method for mianserin hydrochloride and analysis of degradation products by mass spectrometry. Chem Pharm Bull (Tokyo). 2012;60:1387-94 pubmed
Bhasin A, Gurtoo A, Gupta L, Aggarwal G. First case of mirtazepine-induced Stevens-Johnson syndrome from India. Indian J Pharmacol. 2012;44:656-8 pubmed publisher
Kohmura K, Iwamoto K, Aleksic B, Sasada K, Kawano N, Katayama H, et al. Effects of sedative antidepressants on prefrontal cortex activity during verbal fluency task in healthy subjects: a near-infrared spectroscopy study. Psychopharmacology (Berl). 2013;226:75-81 pubmed publisher
Masuzawa M, Taguchi H, Sugimoto T, Kojima H, Matsumoto S, Kojima K, et al. [Case of successful management with mirtazapine for prolonged pain after esophagectomy]. Masui. 2012;61:1003-5 pubmed
Graves S, Rafeyan R, Watts J, Napier T. Mirtazapine, and mirtazapine-like compounds as possible pharmacotherapy for substance abuse disorders: evidence from the bench and the bedside. Pharmacol Ther. 2012;136:343-53 pubmed publisher
Kiblboeck D, Braeuer Mocker M, Siostrzonek P, Reisinger J. A misguided 'pill in the pocket' approach with flecainide leading to cardiac arrest. BMJ Case Rep. 2012;2012: pubmed publisher
Jaquenoud Sirot E, Harenberg S, Vandel P, Lima C, Perrenoud P, Kemmerling K, et al. Multicenter study on the clinical effectiveness, pharmacokinetics, and pharmacogenetics of mirtazapine in depression. J Clin Psychopharmacol. 2012;32:622-9 pubmed
Katsuki A, Yoshimura R, Kishi T, Hori H, Umene Nakano W, Ikenouchi Sugita A, et al. Serum levels of brain-derived neurotrophic factor (BDNF), BDNF gene Val66Met polymorphism, or plasma catecholamine metabolites, and response to mirtazapine in Japanese patients with major depressive disorder (MDD). CNS Spectr. 2012;17:155-63 pubmed publisher
Grubb M, Humphreys W, Josephs J. A semi-automated method for the integrated evaluation of half-life and metabolic soft spots of discovery compounds. Bioanalysis. 2012;4:1747-61 pubmed publisher
Pizzo A, Karam C, Zhang Y, Yano H, Freyberg R, Karam D, et al. The membrane raft protein Flotillin-1 is essential in dopamine neurons for amphetamine-induced behavior in Drosophila. Mol Psychiatry. 2013;18:824-33 pubmed publisher
Yuan J, Johnson R, Huang R, Wichterman J, Jiang H, Hayton K, et al. Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nat Chem Biol. 2009;5:765-71 pubmed publisher
Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed
Willins D, Berry S, Alsayegh L, Backstrom J, Sanders Bush E, Friedman L, et al. Clozapine and other 5-hydroxytryptamine-2A receptor antagonists alter the subcellular distribution of 5-hydroxytryptamine-2A receptors in vitro and in vivo. Neuroscience. 1999;91:599-606 pubmed
Lavoie P, Cherradi S, Elie R. Inhibition of K+-induced Ca2+ uptake in rat hippocampus synaptosomes by mianserin enantiomers. Eur J Pharmacol. 1999;369:387-90 pubmed
Harvey J, Welsh S, Hood H, Romano A. Effect of 5-HT2 receptor antagonists on a cranial nerve reflex in the rabbit: evidence for inverse agonism. Psychopharmacology (Berl). 1999;141:162-8 pubmed
de Boer T. The effects of mirtazapine on central noradrenergic and serotonergic neurotransmission. Int Clin Psychopharmacol. 1995;10 Suppl 4:19-23 pubmed
Shimizu M, Nishida A, Fukuda H, Saito H, Yamawaki S. Effects of chronic exposure to desipramine and mianserin on Ca2+ mobilization induced by noradrenaline, acetylcholine, and high K+ in rat frontocortical neurons. Neuropsychobiology. 1996;33:66-70 pubmed
Leitch I, Boura A, King R. Pharmacological evaluation of the histamine H1 and 5-HT blocking properties of 2-N-(carboxamidinonormianserin) (FCC5): in-vitro studies. J Pharm Pharmacol. 1992;44:315-20 pubmed
product information
Catalog Number :
M2525
Product Name :
Mianserin hydrochloride
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA