Monoclonal Anti-Nicotinic Acetylcholine Receptor (alpha7 Subunit) antibody produced in mouse

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MilliporeSigma

other brands :

FLUKA, Sigma-Aldrich, Roche Applied Science

product type :

antibody

product name :

Monoclonal Anti-Nicotinic Acetylcholine Receptor (alpha7 Subunit) antibody produced in mouse

catalog :

M220

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

mAb 306

reactivity :

human, rat, chicken

application :

immunohistochemistry, immunohistochemistry - frozen section

citations: 4

Reference
Maldifassi M, Martín Sánchez C, Atienza G, Cedillo J, Arnalich F, Bordas A, et al. Interaction of the α7-nicotinic subunit with its human-specific duplicated dupα7 isoform in mammalian cells: Relevance in human inflammatory responses. J Biol Chem. 2018;293:13874-13888 pubmed publisher
Canu N, Pagano I, La Rosa L, Pellegrino M, Ciotti M, Mercanti D, et al. Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents. Front Mol Neurosci. 2017;10:15 pubmed publisher
Cant Barrett K, Spijkers Hagelstein J, Buijs Gladdines J, Uitdehaag J, Smits W, van der Zwet J, et al. MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia. Leukemia. 2016;30:1832-43 pubmed publisher
Almeida Suhett C, Prager E, Pidoplichko V, Figueiredo T, Marini A, Li Z, et al. Reduced GABAergic inhibition in the basolateral amygdala and the development of anxiety-like behaviors after mild traumatic brain injury. PLoS ONE. 2014;9:e102627 pubmed publisher

product information

cat no :

M220

brand :

SIGMA

name :

Monoclonal Anti-Nicotinic Acetylcholine Receptor (alpha7 Subunit) antibody produced in mouse

prod type :

Chemical

name suffix :

~5 mg/mL, clone mAb 306, purified immunoglobulin, buffered aqueous solution

storage :

-20C

storage temp :

-20C

physical form :

Solution in 20 mM Na3PO4, pH 7.2, containing 150 mM NaCl and 0.05% sodium azide.

legal information :

Sold with permission of the Salk Institute

shipped in :

dry ice

mdl no :

MFCD00677279

unspsc code :

12352203

wgk :

form :

buffered aqueous solution

antibody form :

purified immunoglobulin

application(s) :

immunohistochemistry (frozen sections): 1:3,000

species reactivity :

human (denatured), rat (denatured), chicken

concentration :

~5 mg/mL

immunogen :

native and denatured alpha7 subunit (amino acids 380-400, binds alpha-bungarotoxin) of the nicotinic acetylcholine receptor from chicken and the denatured alpha7 subunit from rat.

clone :

mAb 306