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product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Muscimol
catalog :
M1523
citations: 89
Reference
Joo B, Koo J, Lee S. Posterior parietal cortex mediates fear renewal in a novel context. Mol Brain. 2020;13:16 pubmed publisher
Bolding K, Ferbinteanu J, Fox S, Muller R. Place cell firing cannot support navigation without intact septal circuits. Hippocampus. 2020;30:175-191 pubmed publisher
Egger R, Narayanan R, Guest J, Bast A, Udvary D, Messore L, et al. Cortical Output Is Gated by Horizontally Projecting Neurons in the Deep Layers. Neuron. 2019;: pubmed publisher
Han K, Min J, Lee M, Kang B, Park T, Hahn J, et al. Neurovascular Coupling under Chronic Stress Is Modified by Altered GABAergic Interneuron Activity. J Neurosci. 2019;39:10081-10095 pubmed publisher
Bari B, Grossman C, Lubin E, Rajagopalan A, Cressy J, Cohen J. Stable Representations of Decision Variables for Flexible Behavior. Neuron. 2019;103:922-933.e7 pubmed publisher
Nakano Y, Wiechert S, Banfi B. Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019;27:860-871.e8 pubmed publisher
Alexander L, Gaskin P, Sawiak S, Fryer T, Hong Y, Cockcroft G, et al. Fractionating Blunted Reward Processing Characteristic of Anhedonia by Over-Activating Primate Subgenual Anterior Cingulate Cortex. Neuron. 2019;101:307-320.e6 pubmed publisher
Brizuela M, Swoap S, Ang J, Blessing W, Ootsuka Y. Neurons in ventral tegmental area tonically inhibit sympathetic outflow to brown adipose tissue: possible mediation of thermogenic signals from lateral habenula. Am J Physiol Regul Integr Comp Physiol. 2019;316:R6-R12 pubmed publisher
Treviño M, Fregoso E, Sahagun C, Lezama E. An Automated Water Task to Test Visual Discrimination Performance, Adaptive Strategies and Stereotyped Choices in Freely Moving Mice. Front Behav Neurosci. 2018;12:251 pubmed publisher
Tanaka M, Sun F, Li Y, Mooney R. A mesocortical dopamine circuit enables the cultural transmission of vocal behaviour. Nature. 2018;563:117-120 pubmed publisher
Kim J, Kim Y, Lee H, Jin H, Neupane C, Kim S, et al. GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections. Nat Commun. 2018;9:4184 pubmed publisher
Colmers P, Bains J. Balancing tonic and phasic inhibition in hypothalamic corticotropin-releasing hormone neurons. J Physiol. 2018;596:1919-1929 pubmed publisher
Casas Torremocha D, Clascá F, Nunez A. Posterior Thalamic Nucleus Modulation of Tactile Stimuli Processing in Rat Motor and Primary Somatosensory Cortices. Front Neural Circuits. 2017;11:69 pubmed publisher
Li J, Casteels T, Frogne T, Ingvorsen C, Honore C, Courtney M, et al. Artemisinins Target GABAA Receptor Signaling and Impair ? Cell Identity. Cell. 2017;168:86-100.e15 pubmed publisher
Williams P, Martin J. Motor Cortex Activity Organizes the Developing Rubrospinal System. J Neurosci. 2015;35:13363-74 pubmed publisher
Pina M, Young E, Ryabinin A, Cunningham C. The bed nucleus of the stria terminalis regulates ethanol-seeking behavior in mice. Neuropharmacology. 2015;99:627-38 pubmed publisher
Ramesh S, Tyerman S, Xu B, Bose J, Kaur S, Conn V, et al. GABA signalling modulates plant growth by directly regulating the activity of plant-specific anion transporters. Nat Commun. 2015;6:7879 pubmed publisher
Gimenez T, Lorenc M, Jaramillo S. Adaptive categorization of sound frequency does not require the auditory cortex in rats. J Neurophysiol. 2015;114:1137-45 pubmed publisher
Del Rio Bermudez C, Sokoloff G, Blumberg M. Sensorimotor processing in the newborn rat red nucleus during active sleep. J Neurosci. 2015;35:8322-32 pubmed publisher
Wu G, Liu G, Zhang H, Chen C, Liu S, Feng H, et al. Optogenetic stimulation of mPFC pyramidal neurons as a conditioned stimulus supports associative learning in rats. Sci Rep. 2015;5:10065 pubmed publisher
Hummer D, Ehlen J, Larkin T, McNeill J, Pamplin J, Walker C, et al. Sustained activation of GABAA receptors in the suprachiasmatic nucleus mediates light-induced phase delays of the circadian clock: a novel function of ionotropic receptors. Eur J Neurosci. 2015;42:1830-8 pubmed publisher
Kanao M, Kanda H, Huang W, Liu S, Yi H, Candiotti K, et al. Gene Transfer of Glutamic Acid Decarboxylase 67 by Herpes Simplex Virus Vectors Suppresses Neuropathic Pain Induced by Human Immunodeficiency Virus gp120 Combined with ddC in Rats. Anesth Analg. 2015;120:1394-404 pubmed publisher
Wang C, Lin H, Song Y, Hsu Y, Lin S, Hsu P, et al. Protein kinase C-dependent growth-associated protein 43 phosphorylation regulates gephyrin aggregation at developing GABAergic synapses. Mol Cell Biol. 2015;35:1712-26 pubmed publisher
Feja M, Koch M. Frontostriatal systems comprising connections between ventral medial prefrontal cortex and nucleus accumbens subregions differentially regulate motor impulse control in rats. Psychopharmacology (Berl). 2015;232:1291-302 pubmed publisher
Draycott B, Loureiro M, Ahmad T, Tan H, Zunder J, Laviolette S. Cannabinoid transmission in the prefrontal cortex bi-phasically controls emotional memory formation via functional interactions with the ventral tegmental area. J Neurosci. 2014;34:13096-109 pubmed publisher
Seifi M, Brown J, Mills J, Bhandari P, Belelli D, Lambert J, et al. Molecular and functional diversity of GABA-A receptors in the enteric nervous system of the mouse colon. J Neurosci. 2014;34:10361-78 pubmed publisher
Bravo Rivera C, Roman Ortiz C, Brignoni Perez E, Sotres Bayon F, Quirk G. Neural structures mediating expression and extinction of platform-mediated avoidance. J Neurosci. 2014;34:9736-42 pubmed publisher
Holbein W, Bardgett M, Toney G. Blood pressure is maintained during dehydration by hypothalamic paraventricular nucleus-driven tonic sympathetic nerve activity. J Physiol. 2014;592:3783-99 pubmed publisher
Hasanein P, Parviz M. Role of GABAA receptor in modulation of acute thermal pain using a rat model of cholestasis. Pharmacol Biochem Behav. 2014;124:226-30 pubmed publisher
Quadrato G, Elnaggar M, Duman C, Sabino A, Forsberg K, Di Giovanni S. Modulation of GABAA receptor signaling increases neurogenesis and suppresses anxiety through NFATc4. J Neurosci. 2014;34:8630-45 pubmed publisher
Zimmermann J, Jackson A. Closed-loop control of spinal cord stimulation to restore hand function after paralysis. Front Neurosci. 2014;8:87 pubmed publisher
Pezze M, McGarrity S, Mason R, Fone K, Bast T. Too little and too much: hypoactivation and disinhibition of medial prefrontal cortex cause attentional deficits. J Neurosci. 2014;34:7931-46 pubmed publisher
Feja M, Hayn L, Koch M. Nucleus accumbens core and shell inactivation differentially affects impulsive behaviours in rats. Prog Neuropsychopharmacol Biol Psychiatry. 2014;54:31-42 pubmed publisher
Damasceno R, Takakura A, Moreira T. Regulation of the chemosensory control of breathing by Kölliker-Fuse neurons. Am J Physiol Regul Integr Comp Physiol. 2014;307:R57-67 pubmed publisher
Frithiof R, Xing T, McKinley M, May C, Ramchandra R. Intracarotid hypertonic sodium chloride differentially modulates sympathetic nerve activity to the heart and kidney. Am J Physiol Regul Integr Comp Physiol. 2014;306:R567-75 pubmed publisher
Wilden J, Qing K, Hauser S, McBride W, Irazoqui P, Rodd Z. Reduced ethanol consumption by alcohol-preferring (P) rats following pharmacological silencing and deep brain stimulation of the nucleus accumbens shell. J Neurosurg. 2014;120:997-1005 pubmed publisher
Mansoori B, Jean Charles L, Touvykine B, Liu A, Quessy S, Dancause N. Acute inactivation of the contralesional hemisphere for longer durations improves recovery after cortical injury. Exp Neurol. 2014;254:18-28 pubmed publisher
Heilbronner S, Platt M. Causal evidence of performance monitoring by neurons in posterior cingulate cortex during learning. Neuron. 2013;80:1384-91 pubmed publisher
Stopper C, Floresco S. What's better for me? Fundamental role for lateral habenula in promoting subjective decision biases. Nat Neurosci. 2014;17:33-5 pubmed publisher
Corbit L, Leung B, Balleine B. The role of the amygdala-striatal pathway in the acquisition and performance of goal-directed instrumental actions. J Neurosci. 2013;33:17682-90 pubmed publisher
Tanaka M, McKinley M, McAllen R. Role of an excitatory preoptic-raphé pathway in febrile vasoconstriction of the rat's tail. Am J Physiol Regul Integr Comp Physiol. 2013;305:R1479-89 pubmed publisher
Sharpe A, Calderon A, Andrade M, Cunningham J, Mifflin S, Toney G. Chronic intermittent hypoxia increases sympathetic control of blood pressure: role of neuronal activity in the hypothalamic paraventricular nucleus. Am J Physiol Heart Circ Physiol. 2013;305:H1772-80 pubmed publisher
Keiflin R, Reese R, Woods C, Janak P. The orbitofrontal cortex as part of a hierarchical neural system mediating choice between two good options. J Neurosci. 2013;33:15989-98 pubmed publisher
Dutheil S, Escoffier G, Gharbi A, Watabe I, Tighilet B. GABA(A) receptor agonist and antagonist alter vestibular compensation and different steps of reactive neurogenesis in deafferented vestibular nuclei of adult cats. J Neurosci. 2013;33:15555-66 pubmed publisher
Larson T, Wang T, Gale S, Miller K, Thatra N, Caras M, et al. Postsynaptic neural activity regulates neuronal addition in the adult avian song control system. Proc Natl Acad Sci U S A. 2013;110:16640-4 pubmed publisher
Siegel J, Mauk M. Persistent activity in prefrontal cortex during trace eyelid conditioning: dissociating responses that reflect cerebellar output from those that do not. J Neurosci. 2013;33:15272-84 pubmed publisher
Sun Y, Dong Z, Jin T, Ang K, Huang M, Haston K, et al. Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells. elife. 2013;2:e00508 pubmed publisher
Tian J, Dang H, Chen Z, Guan A, Jin Y, Atkinson M, et al. ?-Aminobutyric acid regulates both the survival and replication of human ?-cells. Diabetes. 2013;62:3760-5 pubmed publisher
Zaretsky D, Zaretskaia M, DiMicco J, Durant P, Ross C, Rusyniak D. Independent of 5-HT1A receptors, neurons in the paraventricular hypothalamus mediate ACTH responses from MDMA. Neurosci Lett. 2013;555:42-6 pubmed publisher
Stebelska K. Fungal hallucinogens psilocin, ibotenic acid, and muscimol: analytical methods and biologic activities. Ther Drug Monit. 2013;35:420-42 pubmed publisher
Bhutani N, Sureshbabu R, Farooqui A, Behari M, Goyal V, Murthy A. Queuing of concurrent movement plans by basal ganglia. J Neurosci. 2013;33:9985-97 pubmed publisher
Petri D, Pum M, Vesper J, Huston J, Schnitzler A. GABAA-receptor activation in the subthalamic nucleus compensates behavioral asymmetries in the hemiparkinsonian rat. Behav Brain Res. 2013;252:58-67 pubmed publisher
Constantin S, Iremonger K, Herbison A. In vivo recordings of GnRH neuron firing reveal heterogeneity and dependence upon GABAA receptor signaling. J Neurosci. 2013;33:9394-401 pubmed publisher
Robert C, Bourgeais L, Arreto C, Condés Lara M, Noseda R, Jay T, et al. Paraventricular hypothalamic regulation of trigeminovascular mechanisms involved in headaches. J Neurosci. 2013;33:8827-40 pubmed publisher
Cholvin T, Loureiro M, Cassel R, Cosquer B, Geiger K, De Sa Nogueira D, et al. The ventral midline thalamus contributes to strategy shifting in a memory task requiring both prefrontal cortical and hippocampal functions. J Neurosci. 2013;33:8772-83 pubmed publisher
Torregrossa M, Gordon J, Taylor J. Double dissociation between the anterior cingulate cortex and nucleus accumbens core in encoding the context versus the content of pavlovian cocaine cue extinction. J Neurosci. 2013;33:8370-7 pubmed publisher
Jo Y, Lee J, Mizumori S. Effects of prefrontal cortical inactivation on neural activity in the ventral tegmental area. J Neurosci. 2013;33:8159-71 pubmed publisher
Guo N, Yoshizaki K, Kimura R, Suto F, Yanagawa Y, Osumi N. A sensitive period for GABAergic interneurons in the dentate gyrus in modulating sensorimotor gating. J Neurosci. 2013;33:6691-704 pubmed publisher
Popa D, Spolidoro M, Proville R, Guyon N, Belliveau L, Léna C. Functional role of the cerebellum in gamma-band synchronization of the sensory and motor cortices. J Neurosci. 2013;33:6552-6 pubmed publisher
Janczewski W, Tashima A, Hsu P, Cui Y, Feldman J. Role of inhibition in respiratory pattern generation. J Neurosci. 2013;33:5454-65 pubmed publisher
Peters G, David C, Marcus M, Smith D. The medial prefrontal cortex is critical for memory retrieval and resolving interference. Learn Mem. 2013;20:201-9 pubmed publisher
Xiang Y, Chen X, Li J, Wang S, Faclier G, MacDonald J, et al. Isoflurane regulates atypical type-A ?-aminobutyric acid receptors in alveolar type II epithelial cells. Anesthesiology. 2013;118:1065-75 pubmed publisher
Vanini G, Baghdoyan H. Extrasynaptic GABAA receptors in rat pontine reticular formation increase wakefulness. Sleep. 2013;36:337-43 pubmed publisher
Pais Vieira M, Lebedev M, Wiest M, Nicolelis M. Simultaneous top-down modulation of the primary somatosensory cortex and thalamic nuclei during active tactile discrimination. J Neurosci. 2013;33:4076-93 pubmed publisher
Whitt J, Masri R, Pulimood N, Keller A. Pathological activity in mediodorsal thalamus of rats with spinal cord injury pain. J Neurosci. 2013;33:3915-26 pubmed publisher
Moscarello J, LeDoux J. Active avoidance learning requires prefrontal suppression of amygdala-mediated defensive reactions. J Neurosci. 2013;33:3815-23 pubmed publisher
Cerri M, Mastrotto M, Tupone D, Martelli D, Luppi M, Perez E, et al. The inhibition of neurons in the central nervous pathways for thermoregulatory cold defense induces a suspended animation state in the rat. J Neurosci. 2013;33:2984-93 pubmed publisher
Buzunov E, Mueller A, Straube A, Robinson F. When during horizontal saccades in monkey does cerebellar output affect movement?. Brain Res. 2013;1503:33-42 pubmed publisher
Jin X, Cui N, Zhong W, Jin X, Jiang C. GABAergic synaptic inputs of locus coeruleus neurons in wild-type and Mecp2-null mice. Am J Physiol Cell Physiol. 2013;304:C844-57 pubmed publisher
Samuelsen C, Gardner M, Fontanini A. Thalamic contribution to cortical processing of taste and expectation. J Neurosci. 2013;33:1815-27 pubmed publisher
Bonnevie T, Dunn B, Fyhn M, Hafting T, Derdikman D, Kubie J, et al. Grid cells require excitatory drive from the hippocampus. Nat Neurosci. 2013;16:309-17 pubmed publisher
Morrison K, Bader L, McLaughlin C, Cooper M. Defeat-induced activation of the ventral medial prefrontal cortex is necessary for resistance to conditioned defeat. Behav Brain Res. 2013;243:158-64 pubmed publisher
Diehl G, Wachtel J, Paine T. Cue-induced conditioned activity does not incubate but is mediated by the basolateral amygdala. Pharmacol Biochem Behav. 2013;104:69-79 pubmed publisher
Cha M, Ji Y, Masri R. Motor cortex stimulation activates the incertothalamic pathway in an animal model of spinal cord injury. J Pain. 2013;14:260-9 pubmed publisher
Verdurand M, Fillman S, Weickert C, Zavitsanou K. Increases in [3H]muscimol and [3H]flumazenil binding in the dorsolateral prefrontal cortex in schizophrenia are linked to ?4 and ?2S mRNA levels respectively. PLoS ONE. 2013;8:e52724 pubmed publisher
Potapenko E, Biancardi V, Zhou Y, Stern J. Astrocytes modulate a postsynaptic NMDA-GABAA-receptor crosstalk in hypothalamic neurosecretory neurons. J Neurosci. 2013;33:631-40 pubmed publisher
Stahl J, Thumser Z, Oommen B. The ataxic mouse as a model for studying downbeat nystagmus. J Vestib Res. 2012;22:221-41 pubmed publisher
Petersen J, Bergmann R, Møller H, Jørgensen C, Nielsen B, Kehler J, et al. Synthesis and biological evaluation of 4-(aminomethyl)-1-hydroxypyrazole analogues of muscimol as γ-aminobutyric acid(a) receptor agonists. J Med Chem. 2013;56:993-1006 pubmed publisher
Morishima Y, Toigawa M, Ohmura N, Yoneda T, Tagane Y, Hata Y. Critical period of experience-driven axon retraction in the pharmacologically inhibited visual cortex. Cereb Cortex. 2013;23:2423-8 pubmed publisher
Erlich J, Bush D, LeDoux J. The role of the lateral amygdala in the retrieval and maintenance of fear-memories formed by repeated probabilistic reinforcement. Front Behav Neurosci. 2012;6:16 pubmed publisher
Raharjo W, Ghai V, Dineen A, Bastiani M, Gaudet J. Cell architecture: surrounding muscle cells shape gland cell morphology in the Caenorhabditis elegans pharynx. Genetics. 2011;189:885-97 pubmed publisher
Allen T, Narayanan N, Kholodar Smith D, Zhao Y, Laubach M, Brown T. Imaging the spread of reversible brain inactivations using fluorescent muscimol. J Neurosci Methods. 2008;171:30-8 pubmed publisher
Rozeske R, Der Avakian A, Bland S, Beckley J, Watkins L, Maier S. The medial prefrontal cortex regulates the differential expression of morphine-conditioned place preference following a single exposure to controllable or uncontrollable stress. Neuropsychopharmacology. 2009;34:834-43 pubmed publisher
Olveczky B, Andalman A, Fee M. Vocal experimentation in the juvenile songbird requires a basal ganglia circuit. PLoS Biol. 2005;3:e153 pubmed
Majchrzak M, Di Scala G. GABA and muscimol as reversible inactivation tools in learning and memory. Neural Plast. 2000;7:19-29 pubmed
Krogsgaard Larsen P, Honore T, Hansen J, Curtis D, Lodge D. Structure-activity studies on ibotenic acid and related muscimol analogues. Adv Biochem Psychopharmacol. 1981;27:285-94 pubmed
Krogsgaard Larsen P, Brehm L, Schaumburg K. Muscimol, a psychoactive constituent of Amanita muscaria, as a medicinal chemical model structure. Acta Chem Scand B. 1981;35:311-24 pubmed
DeFeudis F. Binsing studies with muscimol; relation ty synaptic gamma-aminobutyrate receptors. Neuroscience. 1980;5:675-88 pubmed
DeFeudis F. Muscimol and GABA-receptors: basic studies and therapeutic implications. Rev Pure Appl Pharmacol Sci. 1982;3:319-79 pubmed
product information
Catalog Number :
M1523
Product Name :
Muscimol
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA