This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Nocodazole
catalog :
M1404
citations: 1332
Reference
Francis A, Marin M, Singh P, Achuthan V, Prellberg M, Palermino Rowland K, et al. HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains. Nat Commun. 2020;11:3505 pubmed publisher
Nastały P, Purushothaman D, Marchesi S, Poli A, Lendenmann T, Kidiyoor G, et al. Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus. Nat Commun. 2020;11:2122 pubmed publisher
Lauriola A, Martello A, Fantini S, Marverti G, Zanocco Marani T, Davalli P, et al. Depletion of Trichoplein (TpMs) Causes Chromosome Mis-Segregation, DNA Damage and Chromosome Instability in Cancer Cells. Cancers (Basel). 2020;12: pubmed publisher
Hoevenaar W, Janssen A, Quirindongo A, Ma H, Klaasen S, Teixeira A, et al. Degree and site of chromosomal instability define its oncogenic potential. Nat Commun. 2020;11:1501 pubmed publisher
Leung J, Nagayasu E, Hwang Y, Liu J, Pierce P, Phan I, et al. A doublecortin-domain protein of Toxoplasma and its orthologues bind to and modify the structure and organization of tubulin polymers. BMC Mol Cell Biol. 2020;21:8 pubmed publisher
Heusel M, Frank M, Köhler M, Amon S, Frommelt F, Rosenberger G, et al. A Global Screen for Assembly State Changes of the Mitotic Proteome by SEC-SWATH-MS. Cell Syst. 2020;10:133-155.e6 pubmed publisher
Rhodes J, Feldmann A, Hernández Rodríguez B, Díaz N, Brown J, Fursova N, et al. Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells. Cell Rep. 2020;30:820-835.e10 pubmed publisher
Larrieu D, Brunet M, Vargas C, Hanoun N, Ligat L, Dagnon L, et al. The E3 ubiquitin ligase TRIP12 participates in cell cycle progression and chromosome stability. Sci Rep. 2020;10:789 pubmed publisher
Hänsch S, Spona D, Murra G, Köhrer K, Subtil A, Furtado A, et al. Chlamydia-induced curvature of the host-cell plasma membrane is required for infection. Proc Natl Acad Sci U S A. 2020;117:2634-2644 pubmed publisher
Chilewski S, Bhosale D, Dees S, Hutchinson I, Trimble R, Pontiggia L, et al. Development of CAPER peptides for the treatment of triple negative breast cancer. Cell Cycle. 2020;19:432-447 pubmed publisher
Furey C, Jovasevic V, Walsh D. TACC3 Regulates Microtubule Plus-End Dynamics and Cargo Transport in Interphase Cells. Cell Rep. 2020;30:269-283.e6 pubmed publisher
Wang X, Baumann C, De La Fuente R, Viveiros M. CEP215 and AURKA regulate spindle pole focusing and aMTOC organization in mouse oocytes. Reproduction. 2020;159:261-274 pubmed publisher
Kronschnabl P, Grünweller A, Hartmann R, Aigner A, Weirauch U. Inhibition of PIM2 in liver cancer decreases tumor cell proliferation in vitro and in vivo primarily through the modulation of cell cycle progression. Int J Oncol. 2020;56:448-459 pubmed publisher
Liu W, Biton E, Pathania A, Matityahu A, Irudayaraj J, Onn I. Monomeric cohesin state revealed by live-cell single-molecule spectroscopy. EMBO Rep. 2020;21:e48211 pubmed publisher
Naaz F, Ahmad F, Lone B, Pokharel Y, Fuloria N, Fuloria S, et al. Design and synthesis of newer 1,3,4-oxadiazole and 1,2,4-triazole based Topsentin analogues as anti-proliferative agent targeting tubulin. Bioorg Chem. 2020;95:103519 pubmed publisher
Beri P, Popravko A, Yeoman B, Kumar A, Chen K, Hodzic E, et al. Cell Adhesiveness Serves as a Biophysical Marker for Metastatic Potential. Cancer Res. 2020;80:901-911 pubmed publisher
Shih J, Chen H, Lin S, Yeh Y, Shen R, Lang Y, et al. Integrative analyses of noncoding RNAs reveal the potential mechanisms augmenting tumor malignancy in lung adenocarcinoma. Nucleic Acids Res. 2020;48:1175-1191 pubmed publisher
Zheng Z, Zhou Y, Ye L, Lu Q, Zhang K, Zhang J, et al. Histone deacetylase 6 inhibition restores autophagic flux to promote functional recovery after spinal cord injury. Exp Neurol. 2020;324:113138 pubmed publisher
Katsafanas G, Moss B. Specific Anchoring and Local Translation of Poxviral ATI mRNA at Cytoplasmic Inclusion Bodies. J Virol. 2020;94: pubmed publisher
Zhang M, Liang C, Chen Q, Yan H, Xu J, Zhao H, et al. Histone H2A phosphorylation recruits topoisomerase IIα to centromeres to safeguard genomic stability. EMBO J. 2020;39:e101863 pubmed publisher
Kueh A, Eccles S, Tang L, Garnham A, May R, Herold M, et al. HBO1 (KAT7) Does Not Have an Essential Role in Cell Proliferation, DNA Replication, or Histone 4 Acetylation in Human Cells. Mol Cell Biol. 2020;40: pubmed publisher
Kurisawa N, Yukawa M, Koshino H, Onodera T, Toda T, Kimura K. Kolavenic acid analog restores growth in HSET-overproducing fission yeast cells and multipolar mitosis in MDA-MB-231 human cells. Bioorg Med Chem. 2020;28:115154 pubmed publisher
Kim H, He L, Lee S, Park C, Kim D, Han H, et al. Inhibition of osteoclasts differentiation by CDC2-induced NFATc1 phosphorylation. Bone. 2020;131:115153 pubmed publisher
Li M, Yan P, Liu Z, Cai D, Luo Y, Wu X, et al. Muscovy duck reovirus enters susceptible cells via a caveolae-mediated endocytosis-like pathway. Virus Res. 2020;276:197806 pubmed publisher
Hamao K, Ono T, Matsushita M, Hosoya H. ZIP kinase phosphorylated and activated by Rho kinase/ROCK contributes to cytokinesis in mammalian cultured cells. Exp Cell Res. 2020;386:111707 pubmed publisher
Marshall A, Ishak C, Dick F. An RB-Condensin II Complex Mediates Long-Range Chromosome Interactions and Influences Expression at Divergently Paired Genes. Mol Cell Biol. 2020;40: pubmed publisher
Rizk Rabin M, Chaoui Ibadioune S, Vaczlavik A, Ribes C, Polak M, Ragazzon B, et al. Link between steroidogenesis, the cell cycle, and PKA in adrenocortical tumor cells. Mol Cell Endocrinol. 2020;500:110636 pubmed publisher
Brand F, Förster A, Christians A, Bucher M, Thomé C, Raab M, et al. FOCAD loss impacts microtubule assembly, G2/M progression and patient survival in astrocytic gliomas. Acta Neuropathol. 2020;139:175-192 pubmed publisher
Sandhof C, Hoppe S, Druffel Augustin S, Gallrein C, Kirstein J, Voisine C, et al. Reducing INS-IGF1 signaling protects against non-cell autonomous vesicle rupture caused by SNCA spreading. Autophagy. 2020;16:878-899 pubmed publisher
Naik U, Nguyen Q, Harrison R. Binding and uptake of single and dual-opsonized targets by macrophages. J Cell Biochem. 2020;121:183-199 pubmed publisher
Vogel E, Pittman P, Naylor K. The FtsZ Homolog, FszB, Inhibits Mitochondrial Dynamics in Dictyostelium discoideum. Cells. 2019;9: pubmed publisher
Park S, Kang N, Song E, Wie M, Lee E, Hwang S, et al. ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress. Nat Commun. 2019;10:5718 pubmed publisher
Gassaway B, Cardone R, Padyana A, Petersen M, Judd E, Hayes S, et al. Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production. Cell Rep. 2019;29:3394-3404.e9 pubmed publisher
Lee C, Aizawa K, Jiang J, Kung S, Jain R. JLP-centrosome is essential for the microtubule-mediated nucleocytoplasmic transport induced by extracellular stimuli. Sci Adv. 2019;5:eaav0318 pubmed publisher
Xiao W, He W, Zhang Y, Meng L, Lu G, Lin G, et al. In-Frame Variants in STAG3 Gene Cause Premature Ovarian Insufficiency. Front Genet. 2019;10:1016 pubmed publisher
Caragine C, Haley S, Zidovska A. Nucleolar dynamics and interactions with nucleoplasm in living cells. elife. 2019;8: pubmed publisher
Shu S, Iimori M, Wakasa T, Ando K, Saeki H, Oda Y, et al. The balance of forces generated by kinesins controls spindle polarity and chromosomal heterogeneity in tetraploid cells. J Cell Sci. 2019;132: pubmed publisher
Chavez J, Keller A, Zhou B, Tian R, Bruce J. Cellular Interactome Dynamics during Paclitaxel Treatment. Cell Rep. 2019;29:2371-2383.e5 pubmed publisher
Kappelmann Fenzl M, Kuphal S, Krupar R, Schadendorf D, Umansky V, Vardimon L, et al. Complex Formation with Monomeric α-Tubulin and Importin 13 Fosters c-Jun Protein Stability and Is Required for c-Jun's Nuclear Translocation and Activity. Cancers (Basel). 2019;11: pubmed publisher
Odle R, Walker S, Oxley D, Kidger A, Balmanno K, Gilley R, et al. An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis. Mol Cell. 2019;: pubmed publisher
Sarek G, Kotsantis P, Ruis P, Van Ly D, Margalef P, Borel V, et al. CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle. Nature. 2019;: pubmed publisher
Touati S, Hofbauer L, Jones A, Snijders A, Kelly G, Uhlmann F. Cdc14 and PP2A Phosphatases Cooperate to Shape Phosphoproteome Dynamics during Mitotic Exit. Cell Rep. 2019;29:2105-2119.e4 pubmed publisher
Didier M, Macias Romero C, Teulon C, Jourdain P, Roke S. Mapping of real-time morphological changes in the neuronal cytoskeleton with label-free wide-field second-harmonic imaging: a case study of nocodazole. Neurophotonics. 2019;6:045006 pubmed publisher
de Jong M, Langendonk M, Reitsma B, Herbers P, Nijland M, Huls G, et al. WEE1 Inhibition Enhances Anti-Apoptotic Dependency as a Result of Premature Mitotic Entry and DNA Damage. Cancers (Basel). 2019;11: pubmed publisher
Contadini C, Monteonofrio L, Virdia I, Prodosmo A, Valente D, Chessa L, et al. p53 mitotic centrosome localization preserves centrosome integrity and works as sensor for the mitotic surveillance pathway. Cell Death Dis. 2019;10:850 pubmed publisher
Hori A, Nishide K, Yasukuni Y, Haga K, Kakuta W, Ishikawa Y, et al. Prominin-1 Modulates Rho/ROCK-Mediated Membrane Morphology and Calcium-Dependent Intracellular Chloride Flux. Sci Rep. 2019;9:15911 pubmed publisher
Zielinska A, Bellou E, Sharma N, Frombach A, Seres K, Gruhn J, et al. Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs. Curr Biol. 2019;29:3749-3765.e7 pubmed publisher
Dupraz S, Hilton B, Husch A, Santos T, Coles C, Stern S, et al. RhoA Controls Axon Extension Independent of Specification in the Developing Brain. Curr Biol. 2019;29:3874-3886.e9 pubmed publisher
Dudka D, Castrogiovanni C, Liaudet N, Vassal H, Meraldi P. Spindle-Length-Dependent HURP Localization Allows Centrosomes to Control Kinetochore-Fiber Plus-End Dynamics. Curr Biol. 2019;29:3563-3578.e6 pubmed publisher
Boncompain G, Herit F, Tessier S, Lescure A, del Nery E, Gestraud P, et al. Targeting CCR5 trafficking to inhibit HIV-1 infection. Sci Adv. 2019;5:eaax0821 pubmed publisher
Burocziova M, Burdova K, Martinikova A, Kaspárek P, Kleiblova P, Danielsen S, et al. Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon. Cell Death Dis. 2019;10:818 pubmed publisher
Fairchild C, Cheema S, Wong J, Hino K, Simo S, La Torre A. Let-7 regulates cell cycle dynamics in the developing cerebral cortex and retina. Sci Rep. 2019;9:15336 pubmed publisher
Sipos A, Kim K, Sioutas C, Crandall E. Evidence for Nanoparticle-Induced Lysosomal Dysfunction in Lung Adenocarcinoma (A549) Cells. Int J Mol Sci. 2019;20: pubmed publisher
Weiss A, Le Roux Bourdieu M, Zoetemelk M, Ramzy G, Rausch M, Harry D, et al. Identification of a Synergistic Multi-Drug Combination Active in Cancer Cells via the Prevention of Spindle Pole Clustering. Cancers (Basel). 2019;11: pubmed publisher
Roy B, Verma V, Sim J, Fontan A, Joglekar A. Delineating the contribution of Spc105-bound PP1 to spindle checkpoint silencing and kinetochore microtubule attachment regulation. J Cell Biol. 2019;218:3926-3942 pubmed publisher
Patel P, Sun L, Robbins Y, Clavijo P, Friedman J, Silvin C, et al. Enhancing direct cytotoxicity and response to immune checkpoint blockade following ionizing radiation with Wee1 kinase inhibition. Oncoimmunology. 2019;8:e1638207 pubmed publisher
Yang L, Liu X, Song L, Su G, Di A, Bai C, et al. Inhibiting repressive epigenetic modification promotes telomere rejuvenation in somatic cell reprogramming. FASEB J. 2019;33:13982-13997 pubmed publisher
Ritter A, Friemel A, Roth S, Kreis N, Hoock S, Safdar B, et al. Subcutaneous and Visceral Adipose-Derived Mesenchymal Stem Cells: Commonality and Diversity. Cells. 2019;8: pubmed publisher
Baumgart J, Kirchner M, Redemann S, Bond A, Woodruff J, Verbavatz J, et al. Soluble tubulin is significantly enriched at mitotic centrosomes. J Cell Biol. 2019;218:3977-3985 pubmed publisher
Almonacid M, Al Jord A, El Hayek S, Othmani A, Coulpier F, Lemoine S, et al. Active Fluctuations of the Nuclear Envelope Shape the Transcriptional Dynamics in Oocytes. Dev Cell. 2019;51:145-157.e10 pubmed publisher
Roeles J, Tsiavaliaris G. Actin-microtubule interplay coordinates spindle assembly in human oocytes. Nat Commun. 2019;10:4651 pubmed publisher
Denu R, Kaur G, Sass M, Lakkaraju A, Burkard M. Centrosome Amplification in Cancer Disrupts Autophagy and Sensitizes to Autophagy Inhibition. Mol Cancer Res. 2019;: pubmed publisher
Zhang X, Brachner A, Kukolj E, Slade D, Wang Y. SIRT2 deacetylates GRASP55 to facilitate post-mitotic Golgi assembly. J Cell Sci. 2019;132: pubmed publisher
Smith E, Somma D, Kerrigan D, McIntyre Z, Cole J, Liang K, et al. The regulation of sequence specific NF-κB DNA binding and transcription by IKKβ phosphorylation of NF-κB p50 at serine 80. Nucleic Acids Res. 2019;47:11151-11163 pubmed publisher
Wagner K, Kunz K, Piller T, Tascher G, Hölper S, Stehmeier P, et al. The SUMO Isopeptidase SENP6 Functions as a Rheostat of Chromatin Residency in Genome Maintenance and Chromosome Dynamics. Cell Rep. 2019;29:480-494.e5 pubmed publisher
He Y, Yang L, Luo S, Shen W, Yin S, Sun Q. PAK4 Regulates Actin and Microtubule Dynamics during Meiotic Maturation in Mouse Oocyte. Int J Biol Sci. 2019;15:2408-2418 pubmed publisher
Capalbo L, Bassi Z, Geymonat M, Todesca S, Copoiu L, Enright A, et al. The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis. Nat Commun. 2019;10:4513 pubmed publisher
Yang J, Yan W, Li Y, Niu L, Ye H, Chen L. The Natural Compound Withaferin A Covalently Binds to Cys239 of β-Tubulin to Promote Tubulin Degradation. Mol Pharmacol. 2019;96:711-719 pubmed publisher
Brigidi G, Hayes M, Delos Santos N, Hartzell A, Texari L, Lin P, et al. Genomic Decoding of Neuronal Depolarization by Stimulus-Specific NPAS4 Heterodimers. Cell. 2019;179:373-391.e27 pubmed publisher
Conkar D, Bayraktar H, Firat Karalar E. Centrosomal and ciliary targeting of CCDC66 requires cooperative action of centriolar satellites, microtubules and molecular motors. Sci Rep. 2019;9:14250 pubmed publisher
Andronov L, Ouararhni K, Stoll I, Klaholz B, Hamiche A. CENP-A nucleosome clusters form rosette-like structures around HJURP during G1. Nat Commun. 2019;10:4436 pubmed publisher
Oobatake Y, Shimizu N. Double-strand breakage in the extrachromosomal double minutes triggers their aggregation in the nucleus, micronucleation, and morphological transformation. Genes Chromosomes Cancer. 2019;: pubmed publisher
Kashyap A, Fernandez Rodriguez L, Zhao Y, Monaco G, Trefny M, Yoshida N, et al. GEF-H1 Signaling upon Microtubule Destabilization Is Required for Dendritic Cell Activation and Specific Anti-tumor Responses. Cell Rep. 2019;28:3367-3380.e8 pubmed publisher
Sun Z, Lu J, Wu M, Li M, Bai L, Shi Z, et al. Deficiency of PTEN leads to aberrant chromosome segregation through downregulation of MAD2. Mol Med Rep. 2019;20:4235-4243 pubmed publisher
Chang C, Chen C, Grauffel C, Pien Y, Lim C, Tsai S, et al. Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-α. Nat Commun. 2019;10:4307 pubmed publisher
Jeng E, Bhadkamkar V, Ibe N, Gause H, Jiang L, Chan J, et al. Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen. Cell Host Microbe. 2019;26:551-563.e6 pubmed publisher
Liao Y, Fernandopulle M, Wang G, Choi H, Hao L, Drerup C, et al. RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether. Cell. 2019;179:147-164.e20 pubmed publisher
Zheng X, Acharya S, Choe K, Nikhil K, Adelmant G, Satapathy S, et al. A mitotic CDK5-PP4 phospho-signaling cascade primes 53BP1 for DNA repair in G1. Nat Commun. 2019;10:4252 pubmed publisher
Schoonen P, Kok Y, Wierenga E, Bakker B, Foijer F, Spierings D, et al. Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition-mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2-deficient cancer cells. Mol Oncol. 2019;13:2422-2440 pubmed publisher
Vukušić K, Buđa R, Tolić I. Force-generating mechanisms of anaphase in human cells. J Cell Sci. 2019;132: pubmed publisher
Bonner M, Haase J, Swinderman J, Halas H, Miller Jenkins L, Kelly A. Enrichment of Aurora B kinase at the inner kinetochore controls outer kinetochore assembly. J Cell Biol. 2019;218:3237-3257 pubmed publisher
Asai Y, Fukuchi K, Tanno Y, Koitabashi Kiyozuka S, Kiyozuka T, Noda Y, et al. Aurora B kinase activity is regulated by SET/TAF1 on Sgo2 at the inner centromere. J Cell Biol. 2019;218:3223-3236 pubmed publisher
Francia V, Yang K, Deville S, Reker Smit C, Nelissen I, Salvati A. Corona Composition Can Affect the Mechanisms Cells Use to Internalize Nanoparticles. ACS Nano. 2019;13:11107-11121 pubmed publisher
Rudenko L, Wallrabe H, Periasamy A, Siller K, Švindrych Z, Seward M, et al. Intraneuronal Tau Misfolding Induced by Extracellular Amyloid-β Oligomers. J Alzheimers Dis. 2019;71:1125-1138 pubmed publisher
Wang L, Wang J, Jin Y, Zheng J, Yang Y, Xi X. Downregulation of Mad2 and BubR1 increase the malignant potential and nocodazole resistance by compromising spindle assembly checkpoint signaling pathway in cervical carcinogenesis. J Obstet Gynaecol Res. 2019;45:2407-2418 pubmed publisher
Duarte S, Viedma Poyatos Á, Navarro Carrasco E, Martinez A, Pajares M, Perez Sala D. Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division. Nat Commun. 2019;10:4200 pubmed publisher
Psakhye I, Castellucci F, Branzei D. SUMO-Chain-Regulated Proteasomal Degradation Timing Exemplified in DNA Replication Initiation. Mol Cell. 2019;76:632-645.e6 pubmed publisher
Thekkinghat A, Yadav K, Rangarajan P. Apolipoprotein L9 interacts with LC3/GABARAP and is a microtubule-associated protein with a widespread subcellular distribution. Biol Open. 2019;8: pubmed publisher
Hayward D, Bancroft J, Mangat D, Alfonso Pérez T, Dugdale S, McCarthy J, et al. Checkpoint signaling and error correction require regulation of the MPS1 T-loop by PP2A-B56. J Cell Biol. 2019;218:3188-3199 pubmed publisher
Wang H, Nakamura M, Abbott T, Zhao D, Luo K, Yu C, et al. CRISPR-mediated live imaging of genome editing and transcription. Science. 2019;: pubmed publisher
Yen C, Chen S, Hung G, Wu P, Chua W, Lin Y, et al. Expression profile‑driven discovery of AURKA as a treatment target for liposarcoma. Int J Oncol. 2019;55:938-948 pubmed publisher
Trivedi P, Palomba F, Niedzialkowska E, Digman M, Gratton E, Stukenberg P. The inner centromere is a biomolecular condensate scaffolded by the chromosomal passenger complex. Nat Cell Biol. 2019;21:1127-1137 pubmed publisher
Hata S, Pastor Peidro A, Panic M, Liu P, Atorino E, Funaya C, et al. The balance between KIFC3 and EG5 tetrameric kinesins controls the onset of mitotic spindle assembly. Nat Cell Biol. 2019;21:1138-1151 pubmed publisher
Toledo Jacobo L, Henson J, Shuster C. Cytoskeletal polarization and cytokinetic signaling drives polar lobe formation in spiralian embryos. Dev Biol. 2019;456:201-211 pubmed publisher
Dong L, Gong J, Wang Y, He J, You D, Zhou Y, et al. Chiral geometry regulates stem cell fate and activity. Biomaterials. 2019;222:119456 pubmed publisher
Yuan R, Liu Q, Segeren H, Yuniati L, Guardavaccaro D, Lebbink R, et al. Cyclin F-dependent degradation of E2F7 is critical for DNA repair and G2-phase progression. EMBO J. 2019;38:e101430 pubmed publisher
Fréal A, Rai D, Tas R, Pan X, Katrukha E, van de Willige D, et al. Feedback-Driven Assembly of the Axon Initial Segment. Neuron. 2019;104:305-321.e8 pubmed publisher
Sawada J, Ishii H, Matsuno K, Sato M, Suzuki Y, Asai A. Selective Inhibition of Spindle Microtubules by a Tubulin-Binding Quinazoline Derivative. Mol Pharmacol. 2019;96:609-618 pubmed publisher
Huo S, Wu X, Ye C, Hu M, Li W, Zhang L, et al. In Situ Fluorescence Tracking Toxic Metabolite Mono-2-ethylhexyl phthalate (MEHP) of Di-(2-ethylhexyl) phthalate (DEHP) in HeLa Cells. Chem Res Toxicol. 2019;32:2006-2015 pubmed publisher
Feng J, Wu Y, Zhang L, Li Y, Liu S, Wang H, et al. Enhanced Chemical Stability, Intestinal Absorption, and Intracellular Antioxidant Activity of Cyanidin-3-O-glucoside by Composite Nanogel Encapsulation. J Agric Food Chem. 2019;67:10432-10447 pubmed publisher
Guimbal S, Morel A, Guérit D, Chardon M, Blangy A, Vives V. Dock5 is a new regulator of microtubule dynamic instability in osteoclasts. Biol Cell. 2019;111:271-283 pubmed publisher
Jung I, Jung D, Chung Y, Kim K, Park S. Iroquois Homeobox 1 Acts as a True Tumor Suppressor in Multiple Organs by Regulating Cell Cycle Progression. Neoplasia. 2019;21:1003-1014 pubmed publisher
Panier S, Maric M, Hewitt G, Mason Osann E, Gali H, Dai A, et al. SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance. Mol Cell. 2019;76:27-43.e11 pubmed publisher
Wei Y, Yang T, Kovacs T, Yang W. C-terminal kinesin motor es-KIFC1 regulates nuclear formation during spermiogenesis in Chinese mitten crab Eriocheir sinensis. Gene. 2019;719:144074 pubmed publisher
Park S, Lin C, Ren N, Angus S, Dittmer D, Foote M, et al. Inhibition of Aurora A Kinase in Combination with Chemotherapy Induces Synthetic Lethality and Overcomes Chemoresistance in Myc-Overexpressing Lymphoma. Target Oncol. 2019;14:563-575 pubmed publisher
Li M, Xu X, Zhang J, Liu M, Wang W, Gao Y, et al. NudC-like protein 2 restrains centriole amplification by stabilizing HERC2. Cell Death Dis. 2019;10:628 pubmed publisher
Tang J, Frascaroli G, Lebbink R, Ostermann E, Brune W. Human cytomegalovirus glycoprotein B variants affect viral entry, cell fusion, and genome stability. Proc Natl Acad Sci U S A. 2019;116:18021-18030 pubmed publisher
Khalaf B, Roncador A, Pischedda F, Casini A, Thomas S, Piccoli G, et al. Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons. J Cell Sci. 2019;132: pubmed publisher
Datar A, Ameeramja J, Bhat A, Srivastava R, Mishra A, Bernal R, et al. The Roles of Microtubules and Membrane Tension in Axonal Beading, Retraction, and Atrophy. Biophys J. 2019;117:880-891 pubmed publisher
Burdova K, Yang H, Faedda R, Hume S, Chauhan J, Ebner D, et al. E2F1 proteolysis via SCF-cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition. EMBO J. 2019;38:e101443 pubmed publisher
Barbosa A, Lim K, Mari M, Edgar J, Gal L, Sterk P, et al. Compartmentalized Synthesis of Triacylglycerol at the Inner Nuclear Membrane Regulates Nuclear Organization. Dev Cell. 2019;50:755-766.e6 pubmed publisher
Dutta P, Islam S, Choppara S, Sengupta P, Kumar A, Kumar A, et al. The tumor suppressor FBXO31 preserves genomic integrity by regulating DNA replication and segregation through precise control of cyclin A levels. J Biol Chem. 2019;294:14879-14895 pubmed publisher
Cheng Y, Luo H, Izzo F, Pickering B, Nguyen D, Myers R, et al. m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment. Cell Rep. 2019;28:1703-1716.e6 pubmed publisher
Nardi F, Fitchev P, Brooks K, Franco O, Cheng K, Hayward S, et al. Lipid droplet velocity is a microenvironmental sensor of aggressive tumors regulated by V-ATPase and PEDF. Lab Invest. 2019;99:1822-1834 pubmed publisher
Ishii S, Matsuura A, Itakura E. Identification of a factor controlling lysosomal homeostasis using a novel lysosomal trafficking probe. Sci Rep. 2019;9:11635 pubmed publisher
Huang X, Zhang Q, Lou Y, Wang J, Zhao X, Wang L, et al. USP22 Deubiquitinates CD274 to Suppress Anticancer Immunity. Cancer Immunol Res. 2019;: pubmed publisher
Wilhelm T, Olziersky A, Harry D, De Sousa F, Vassal H, Eskat A, et al. Mild replication stress causes chromosome mis-segregation via premature centriole disengagement. Nat Commun. 2019;10:3585 pubmed publisher
Sengupta S, Rothenberg K, Li H, Hoffman B, Bursac N. Altering integrin engagement regulates membrane localization of Kir2.1 channels. J Cell Sci. 2019;132: pubmed publisher
Muñoz Estrada J, Ferland R. Ahi1 promotes Arl13b ciliary recruitment, regulates Arl13b stability and is required for normal cell migration. J Cell Sci. 2019;132: pubmed publisher
Salas Armenteros I, Barroso S, Rondon A, Perez M, Andújar E, Luna R, et al. Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability. Cell Rep. 2019;28:1551-1563.e7 pubmed publisher
Van Steenbergen V, Boesmans W, Li Z, de Coene Y, Vints K, Baatsen P, et al. Molecular understanding of label-free second harmonic imaging of microtubules. Nat Commun. 2019;10:3530 pubmed publisher
He R, Wang M, Zhao C, Shen M, Yu Y, He L, et al. TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells. J Exp Clin Cancer Res. 2019;38:340 pubmed publisher
Dasgupta S, Vliet S, Cheng V, Mitchell C, Kirkwood J, Vollaro A, et al. Complex Interplay Among Nuclear Receptor Ligands, Cytosine Methylation, and the Metabolome in Driving Tris(1,3-dichloro-2-propyl)phosphate-Induced Epiboly Defects in Zebrafish. Environ Sci Technol. 2019;53:10497-10505 pubmed publisher
Beer K, Fazeli G, Judasova K, Irmisch L, Causemann J, Mansfeld J, et al. Degron-tagged reporters probe membrane topology and enable the specific labelling of membrane-wrapped structures. Nat Commun. 2019;10:3490 pubmed publisher
Groebner J, Giron Bravo M, Rothberg M, Adhikari R, Tuma D, Tuma P. Alcohol-induced microtubule acetylation leads to the accumulation of large, immobile lipid droplets. Am J Physiol Gastrointest Liver Physiol. 2019;: pubmed publisher
Prikrylova T, Robertson J, Ferrucci F, Konorska D, Aanes H, Manaf A, et al. 5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication. Sci Rep. 2019;9:11065 pubmed publisher
Wang Y, Liu X, Zhang Y, Wan B, Zhang J, He W, et al. Exposure to a 50 Hz magnetic field at 100 µT exerts no DNA damage in cardiomyocytes. Biol Open. 2019;8: pubmed publisher
Wei M, Zhu Z, Wu J, Wang Y, Geng J, Qin Z. DRAM1 deficiency affects the organization and function of the Golgi apparatus. Cell Signal. 2019;63:109375 pubmed publisher
Hoock S, Ritter A, Steinhäuser K, Roth S, Behrends C, Oswald F, et al. RITA modulates cell migration and invasion by affecting focal adhesion dynamics. Mol Oncol. 2019;13:2121-2141 pubmed publisher
Mittal R, Debs L, Patel A, Nguyen D, Blackwelder P, Yan D, et al. Otopathogenic Staphylococcus aureus Invades Human Middle Ear Epithelial Cells Primarily through Cholesterol Dependent Pathway. Sci Rep. 2019;9:10777 pubmed publisher
Xie S, Yan B, Feng J, Wu Y, He N, Sun L, et al. Altering microtubule stability affects microtubule clearance and nuclear extrusion during erythropoiesis. J Cell Physiol. 2019;234:19833-19841 pubmed publisher
Oka N, Kasamatsu A, Endo Sakamoto Y, Eizuka K, Wagai S, Koide Ishida N, et al. Centromere Protein N Participates in Cellular Proliferation of Human Oral Cancer by Cell-Cycle Enhancement. J Cancer. 2019;10:3728-3734 pubmed publisher
van de Vlekkert D, Demmers J, Nguyen X, Campos Y, Machado E, Annunziata I, et al. Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis. Sci Adv. 2019;5:eaav3270 pubmed publisher
Královec K, Havelek R, Krocova E, Kučírková L, Hauschke M, Bartacek J, et al. Silica coated iron oxide nanoparticles-induced cytotoxicity, genotoxicity and its underlying mechanism in human HK-2 renal proximal tubule epithelial cells. Mutat Res. 2019;844:35-45 pubmed publisher
Zhovmer A, Tabdanov E, Miao H, Wen H, Chen J, Luo X, et al. The role of nonmuscle myosin 2A and 2B in the regulation of mesenchymal cell contact guidance. Mol Biol Cell. 2019;30:1961-1973 pubmed publisher
Mishra P, Martin D, Androulakis I, Moghe P. Fluorescence Imaging of Actin Turnover Parses Early Stem Cell Lineage Divergence and Senescence. Sci Rep. 2019;9:10377 pubmed publisher
Olbrich T, Vega Sendino M, Murga M, de Carcer G, Malumbres M, Ortega S, et al. A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells. Cell Rep. 2019;28:597-604.e4 pubmed publisher
Chiu S, Chen K, Hsia J, Chuang C, Wan C, Wei T, et al. Overexpression of Aurora-A bypasses cytokinesis through phosphorylation of suppressed in lung cancer. Am J Physiol Cell Physiol. 2019;317:C600-C612 pubmed publisher
Taulet N, Douanier A, Vitre B, Anguille C, Maurin J, Dromard Y, et al. IFT88 controls NuMA enrichment at k-fibers minus-ends to facilitate their re-anchoring into mitotic spindles. Sci Rep. 2019;9:10311 pubmed publisher
Lee B, Lee M, Yun S, Kim K, Choi I, Park S. Silver nanoparticles induce reactive oxygen species-mediated cell cycle delay and synergistic cytotoxicity with 3-bromopyruvate in Candida albicans, but not in Saccharomyces cerevisiae. Int J Nanomedicine. 2019;14:4801-4816 pubmed publisher
Trogden K, Zhu X, Lee J, Wright C, Gu G, Kaverina I. Regulation of Glucose-Dependent Golgi-Derived Microtubules by cAMP/EPAC2 Promotes Secretory Vesicle Biogenesis in Pancreatic β Cells. Curr Biol. 2019;29:2339-2350.e5 pubmed publisher
Cabral G, Laos T, Dumont J, Dammermann A. Differential Requirements for Centrioles in Mitotic Centrosome Growth and Maintenance. Dev Cell. 2019;50:355-366.e6 pubmed publisher
Zierhut C, Yamaguchi N, Paredes M, Luo J, Carroll T, Funabiki H. The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death. Cell. 2019;178:302-315.e23 pubmed publisher
Pongrac I, Radmilović M, Ahmed L, Mlinarić H, Regul J, Škokić S, et al. D-mannose-Coating of Maghemite Nanoparticles Improved Labeling of Neural Stem Cells and Allowed Their Visualization by ex vivo MRI after Transplantation in the Mouse Brain. Cell Transplant. 2019;28:553-567 pubmed publisher
Yuan F, Jin X, Li D, Song Y, Zhang N, Yang X, et al. ULK1 phosphorylates Mad1 to regulate spindle assembly checkpoint. Nucleic Acids Res. 2019;47:8096-8110 pubmed publisher
Wu X, Li S, Hu X, Xiang X, Halloran M, Yang L, et al. mTOR Signaling Upregulates CDC6 via Suppressing miR-3178 and Promotes the Loading of DNA Replication Helicase. Sci Rep. 2019;9:9805 pubmed publisher
Pisciottani A, Biancolillo L, Ferrara M, Valente D, Sardina F, Monteonofrio L, et al. HIPK2 Phosphorylates the Microtubule-Severing Enzyme Spastin at S268 for Abscission. Cells. 2019;8: pubmed publisher
Zhang Q, Zhang F, Li S, Liu R, Jin T, Dou Y, et al. A Multifunctional Nanotherapy for Targeted Treatment of Colon Cancer by Simultaneously Regulating Tumor Microenvironment. Theranostics. 2019;9:3732-3753 pubmed publisher
Santibáñez Andrade M, Sánchez Pérez Y, Chirino Y, Morales Bárcenas R, Herrera L, García Cuellar C. Airborne particulate matter induces mitotic slippage and chromosomal missegregation through disruption of the spindle assembly checkpoint (SAC). Chemosphere. 2019;235:794-804 pubmed publisher
Chen Y, Frost S, Khushi M, Cantrill L, Yu H, Arthur J, et al. Delayed recruiting of TPD52 to lipid droplets - evidence for a "second wave" of lipid droplet-associated proteins that respond to altered lipid storage induced by Brefeldin A treatment. Sci Rep. 2019;9:9790 pubmed publisher
Witzel P, Götz M, Lanoiselée Y, Franosch T, Grebenkov D, Heinrich D. Heterogeneities Shape Passive Intracellular Transport. Biophys J. 2019;117:203-213 pubmed publisher
Park J, Lee J, Lee D. Identification of Protein Phosphatase 4 Inhibitory Protein That Plays an Indispensable Role in DNA Damage Response. Mol Cells. 2019;42:546-556 pubmed publisher
Yamada M, Hayashi K. Microtubule nucleation in the cytoplasm of developing cortical neurons and its regulation by brain-derived neurotrophic factor. Cytoskeleton (Hoboken). 2019;76:339-345 pubmed publisher
Farfel Becker T, Roney J, Cheng X, Li S, Cuddy S, Sheng Z. Neuronal Soma-Derived Degradative Lysosomes Are Continuously Delivered to Distal Axons to Maintain Local Degradation Capacity. Cell Rep. 2019;28:51-64.e4 pubmed publisher
Booth A, Yue Z, Eykelenboom J, Stiff T, Luxton G, Hochegger H, et al. Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis. elife. 2019;8: pubmed publisher
Horita K, Kurosaki H, Nakatake M, Ito M, Kono H, Nakamura T. Long noncoding RNA UCA1 enhances sensitivity to oncolytic vaccinia virus by sponging miR-18a/miR-182 and modulating the Cdc42/filopodia axis in colorectal cancer. Biochem Biophys Res Commun. 2019;516:831-838 pubmed publisher
Parant M, Sohm B, Flayac J, Perrat E, Chuburu F, Cadiou C, et al. Impact of gadolinium-based contrast agents on the growth of fish cells lines. Ecotoxicol Environ Saf. 2019;182:109385 pubmed publisher
Ni Y, Schmidt K, Werner B, Koenig J, Guldner I, Schnepp P, et al. Death effector domain-containing protein induces vulnerability to cell cycle inhibition in triple-negative breast cancer. Nat Commun. 2019;10:2860 pubmed publisher
Kokubu Y, Nagino T, Sasa K, Oikawa T, Miyake K, Kume A, et al. Phenotypic Drug Screening for Dysferlinopathy Using Patient-Derived Induced Pluripotent Stem Cells. Stem Cells Transl Med. 2019;: pubmed publisher
So C, Seres K, Steyer A, Mönnich E, Clift D, Pejkovska A, et al. A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes. Science. 2019;364: pubmed publisher
Fazal F, Han S, Parker K, Kaewsapsak P, Xu J, Boettiger A, et al. Atlas of Subcellular RNA Localization Revealed by APEX-Seq. Cell. 2019;: pubmed publisher
Chang C, Weigel A, Ioannou M, Pasolli H, Xu C, Peale D, et al. Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III. J Cell Biol. 2019;: pubmed publisher
Qu Q, Zhang Q, Yang L, Chen Y, Liu H. SET binding to Sgo1 inhibits Sgo1-cohesin interactions and promotes chromosome segregation. J Cell Biol. 2019;: pubmed publisher
Roberti A, Bensi M, Mazzagatti A, Piras F, Nergadze S, Giulotto E, et al. Satellite DNA at the Centromere is Dispensable for Segregation Fidelity. Genes (Basel). 2019;10: pubmed publisher
Boginya A, Detroja R, Matityahu A, Frenkel Morgenstern M, Onn I. The chromatin remodeler Chd1 regulates cohesin in budding yeast and humans. Sci Rep. 2019;9:8929 pubmed publisher
Kumar H, Pushpa K, Kumari A, Verma K, Pergu R, Mylavarapu S. The Exocyst complex and Rab5 are required for abscission by localizing ESCRT III subunits to the cytokinetic bridge. J Cell Sci. 2019;: pubmed publisher
Tan H, Wu C, Li J, Tan Z, Hoffman J, Fry C, et al. DNMT3B shapes the mCA landscape and regulates mCG for promoter bivalency in human embryonic stem cells. Nucleic Acids Res. 2019;47:7460-7475 pubmed publisher
Bala Bhaskara Rao K, Katragunta K, Sarma U, Jain N. Abundance of d-2-hydroxyglutarate in G2/M is determined by FOXM1 in mutant IDH1-expressing cells. FEBS Lett. 2019;: pubmed publisher
Zhang W, Feng Y, Guo Q, Guo W, Xu H, Li X, et al. SIRT1 modulates cell cycle progression by regulating CHK2 acetylation-phosphorylation. Cell Death Differ. 2019;: pubmed publisher
Griffith A, Zhang T, Burkert S, Adiguzel Z, Acilan C, Star A, et al. Characterizing the Cellular Response to Nitrogen-Doped Carbon Nanocups. Nanomaterials (Basel). 2019;9: pubmed publisher
Rodriguez Sawicki L, Garcia K, Corsico B, Scaglia N. De novo lipogenesis at the mitotic exit is used for nuclear envelope reassembly/expansion. Implications for combined chemotherapy. Cell Cycle. 2019;18:1646-1659 pubmed publisher
Huang Y, Lin L, Liu X, Ye S, Yao P, Wang W, et al. BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res. 2019;: pubmed publisher
Chapard C, Jones R, van Oepen T, Scheinost J, Nasmyth K. Sister DNA Entrapment between Juxtaposed Smc Heads and Kleisin of the Cohesin Complex. Mol Cell. 2019;: pubmed publisher
Serpico A, D Alterio G, Vetrei C, Della Monica R, Nardella L, Visconti R, et al. Wee1 Rather Than Plk1 Is Inhibited by AZD1775 at Therapeutically Relevant Concentrations. Cancers (Basel). 2019;11: pubmed publisher
Mani M, Thao D, Kim B, Lee U, Kim D, Jang S, et al. DRG2 knockdown induces Golgi fragmentation via GSK3β phosphorylation and microtubule stabilization. Biochim Biophys Acta Mol Cell Res. 2019;: pubmed publisher
Saez J, Diaz J, Ibáñez J, Bozo J, Cabrera Reyes F, Alamo M, et al. The exocyst controls lysosome secretion and antigen extraction at the immune synapse of B cells. J Cell Biol. 2019;: pubmed publisher
García Pastor C, Blázquez Serra R, Bosch R, Lucio Cazaña F, Fernández Martínez A. Apoptosis and cell proliferation in proximal tubular cells exposed to apoptotic bodies. Novel pathophysiological implications in cisplatin-induced renal injury. Biochim Biophys Acta Mol Basis Dis. 2019;: pubmed publisher
Pladevall Morera D, Munk S, Ingham A, Garribba L, Albers E, Liu Y, et al. Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability. Nucleic Acids Res. 2019;47:8004-8018 pubmed publisher
Li M, Lee A, Kim S, Shrinidhi A, Park K, Kim K. Cucurbit[7]uril-conjugated dyes as live cell imaging probes: investigation on their cellular uptake and excretion pathways. Org Biomol Chem. 2019;: pubmed publisher
Hossain D, Barbelanne M, Tsang W. Requirement of NPHP5 in the hierarchical assembly of basal feet associated with basal bodies of primary cilia. Cell Mol Life Sci. 2019;: pubmed publisher
Bernier L, Bohlen C, York E, Choi H, Kamyabi A, Dissing Olesen L, et al. Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia. Cell Rep. 2019;27:2895-2908.e4 pubmed publisher
Ahn J, Cho M, Sohn S, Lee J. Inhibition of PP2A activity by H2O2 during mitosis disrupts nuclear envelope reassembly and alters nuclear shape. Exp Mol Med. 2019;51:64 pubmed publisher
Nechemia Arbely Y, Miga K, Shoshani O, Aslanian A, McMahon M, Lee A, et al. DNA replication acts as an error correction mechanism to maintain centromere identity by restricting CENP-A to centromeres. Nat Cell Biol. 2019;21:743-754 pubmed publisher
Shao Y, Chong W, Liu X, Xu Y, Zhang H, Xu Q, et al. Alternative splicing-derived intersectin1-L and intersectin1-S exert opposite function in glioma progression. Cell Death Dis. 2019;10:431 pubmed publisher
Liu S, Li J, Wang T, Xu J, Liu Z, Wang H, et al. Illumination of cell cycle progression by multi-fluorescent sensing system. Cell Cycle. 2019;18:1364-1378 pubmed publisher
Clijsters L, Hoencamp C, Calis J, Marzio A, Handgraaf S, Cuitino M, et al. Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs. Mol Cell. 2019;74:1264-1277.e7 pubmed publisher
Taveras C, Liu C, Mao Y. A tension-independent mechanism reduces Aurora B-mediated phosphorylation upon microtubule capture by CENP-E at the kinetochore. Cell Cycle. 2019;18:1349-1363 pubmed publisher
Traynor S, Møllegaard N, Jørgensen M, Brückmann N, Pedersen C, Terp M, et al. Remodeling and destabilization of chromosome 1 pericentromeric heterochromatin by SSX proteins. Nucleic Acids Res. 2019;47:6668-6684 pubmed publisher
Velichko A, Petrova N, Luzhin A, Strelkova O, Ovsyannikova N, Kireev I, et al. Hypoosmotic stress induces R loop formation in nucleoli and ATR/ATM-dependent silencing of nucleolar transcription. Nucleic Acids Res. 2019;: pubmed publisher
Rafiq N, Nishimura Y, Plotnikov S, Thiagarajan V, Zhang Z, Shi S, et al. A mechano-signalling network linking microtubules, myosin IIA filaments and integrin-based adhesions. Nat Mater. 2019;18:638-649 pubmed publisher
Tsai H, Fu S, Tseng L, Chiu J, Lin C. hnRNPK S379 phosphorylation participates in migration regulation of triple negative MDA-MB-231 cells. Sci Rep. 2019;9:7611 pubmed publisher
Hayashi Takanaka Y, Kina Y, Nakamura F, Yamazaki S, Harata M, Soest R, et al. Effect of mycalolides isolated from a marine sponge Mycale aff. nullarosette on actin in living cells. Sci Rep. 2019;9:7540 pubmed publisher
Cheng Z, Liu F, Tian H, Xu Z, Chai X, Luo D, et al. Impairing the maintenance of germinative cells in Echinococcus multilocularis by targeting Aurora kinase. PLoS Negl Trop Dis. 2019;13:e0007425 pubmed publisher
Tan X, Zhang Y, Wang Q, Ren T, Gou J, Guo W, et al. Cell-penetrating peptide together with PEG-modified mesostructured silica nanoparticles promotes mucous permeation and oral delivery of therapeutic proteins and peptides. Biomater Sci. 2019;7:2934-2950 pubmed publisher
Miteva K, Pedicini L, Wilson L, Jayasinghe I, Slip R, Marszalek K, et al. Rab46 integrates Ca2+ and histamine signaling to regulate selective cargo release from Weibel-Palade bodies. J Cell Biol. 2019;: pubmed publisher
Shamipour S, Kardos R, Xue S, Hof B, Hannezo E, Heisenberg C. Bulk Actin Dynamics Drive Phase Segregation in Zebrafish Oocytes. Cell. 2019;: pubmed publisher
Ma X, Li H, Cao X, Liu Z, He D. Multiphosphorylation and cellular localization of poly(rC) binding protein 1 during mitosis in hela cell. Biotechnol Lett. 2019;41:711-717 pubmed publisher
Doolin M, Ornstein T, Stroka K. Nuclear Deformation in Response to Mechanical Confinement is Cell Type Dependent. Cells. 2019;8: pubmed publisher
Yang Y, Cong H, Du N, Han X, Song L, Zhang W, et al. Mitochondria Redistribution in Enterovirus A71 Infected Cells and Its Effect on Virus Replication. Virol Sin. 2019;: pubmed publisher
Douanne T, André Grégoire G, Thys A, Trillet K, Gavard J, Bidere N. CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1. Cell Rep. 2019;27:1657-1665.e4 pubmed publisher
Wang J, Chen M, Li S, Ye R. Targeted Delivery of a Ligand-Drug Conjugate via Formyl Peptide Receptor 1 through Cholesterol-Dependent Endocytosis. Mol Pharm. 2019;16:2636-2647 pubmed publisher
Yu F, Hubrack S, Chakraborty S, Sun L, Alcantara Adap E, Kulkarni R, et al. Remodeling of ER-plasma membrane contact sites but not STIM1 phosphorylation inhibits Ca2+ influx in mitosis. Proc Natl Acad Sci U S A. 2019;116:10392-10401 pubmed publisher
Rosas Salvans M, Scrofani J, Modol A, Vernos I. DnaJB6 is a RanGTP-regulated protein required for microtubule organization during mitosis. J Cell Sci. 2019;132: pubmed publisher
Gao X, De Mazière A, Iaea D, Arthur C, Klumperman J, Ciferri C, et al. Visualizing the cellular route of entry of a cystine-knot peptide with Xfect transfection reagent by electron microscopy. Sci Rep. 2019;9:6907 pubmed publisher
Shi Y, Wang L, Yu P, Liu Y, Chen W. MicroRNA‑486‑5p inhibits the growth of human hypertrophic scar fibroblasts by regulating Smad2 expression. Mol Med Rep. 2019;19:5203-5210 pubmed publisher
Lopes da Silva M, McCormack J, Burden J, Harrison Lavoie K, Ferraro F, Cutler D. A GBF1-Dependent Mechanism for Environmentally Responsive Regulation of ER-Golgi Transport. Dev Cell. 2019;49:786-801.e6 pubmed publisher
Wu Q, Zhang W, Xue L, Wang Y, Fu M, Ma L, et al. APC/C-CDH1-regulated IDH3β coordinates with the cell cycle to promote cell proliferation. Cancer Res. 2019;: pubmed publisher
Colicino E, Stevens K, Curtis E, Rathbun L, Bates M, Manikas J, et al. Chromosome misalignment is associated with PLK1 activity at cenexin-positive mitotic centrosomes. Mol Biol Cell. 2019;:mbcE18120817 pubmed publisher
Bolhaqueiro A, Ponsioen B, Bakker B, Klaasen S, Kucukkose E, van Jaarsveld R, et al. Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids. Nat Genet. 2019;51:824-834 pubmed publisher
Yang D, Liu D, Deng H, Zhang J, Qin M, Yuan L, et al. Transferrin Functionization Elevates Transcytosis of Nanogranules across Epithelium by Triggering Polarity-Associated Transport Flow and Positive Cellular Feedback Loop. ACS Nano. 2019;13:5058-5076 pubmed publisher
Mathewson A, Berman D, Moens C. Microtubules are required for the maintenance of planar cell polarity in monociliated floorplate cells. Dev Biol. 2019;452:21-33 pubmed publisher
Bui D, Li J. DNA Rereplication Is Susceptible to Nucleotide-Level Mutagenesis. Genetics. 2019;212:445-460 pubmed publisher
Wang Y, Han T, Gan M, Guo M, Xie C, Jin J, et al. A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer. Cell Cycle. 2019;18:1019-1032 pubmed publisher
Pagotto S, Veronese A, Soranno A, Balatti V, Ramassone A, Guanciali Franchi P, et al. HNRNPL Restrains miR-155 Targeting of BUB1 to Stabilize Aberrant Karyotypes of Transformed Cells in Chronic Lymphocytic Leukemia. Cancers (Basel). 2019;11: pubmed publisher
Fisher P, Spencer H, Thomas Oates J, Wood A, Ungar D. Modeling Glycan Processing Reveals Golgi-Enzyme Homeostasis upon Trafficking Defects and Cellular Differentiation. Cell Rep. 2019;27:1231-1243.e6 pubmed publisher
Farina F, Ramkumar N, Brown L, Samandar Eweis D, Anstatt J, WARING T, et al. Local actin nucleation tunes centrosomal microtubule nucleation during passage through mitosis. EMBO J. 2019;38: pubmed publisher
Tsai T, Collins S, Chan C, Hadjitheodorou A, Lam P, Lou S, et al. Efficient Front-Rear Coupling in Neutrophil Chemotaxis by Dynamic Myosin II Localization. Dev Cell. 2019;49:189-205.e6 pubmed publisher
Horita K, Kurosaki H, Nakatake M, Kuwano N, Oishi T, Itamochi H, et al. lncRNA UCA1-Mediated Cdc42 Signaling Promotes Oncolytic Vaccinia Virus Cell-to-Cell Spread in Ovarian Cancer. Mol Ther Oncolytics. 2019;13:35-48 pubmed publisher
Li G, Chen T, Wang Y, Zhang J, Guo J, Wu H. Interaction between microfilament and microtubule- dependent tensions and ischemia/hypoxic-induced alteration of structural tension in neuronal cells. Brain Res Bull. 2019;149:222-230 pubmed publisher
Kent I, Zhang Q, Katiyar A, Li Y, Pathak S, Dickinson R, et al. Apical cell protrusions cause vertical deformation of the soft cancer nucleus. J Cell Physiol. 2019;: pubmed publisher
Kuo C, Schelz Z, Toth B, Vasas A, Ocsovszki I, Chang F, et al. Investigation of natural phenanthrenes and the antiproliferative potential of juncusol in cervical cancer cell lines. Phytomedicine. 2019;58:152770 pubmed publisher
Yamamoto S, Kitagawa D. Self-organization of Plk4 regulates symmetry breaking in centriole duplication. Nat Commun. 2019;10:1810 pubmed publisher
Sudo K, Van Dao C, Miyamoto A, Shiraishi M. Comparative analysis of in vitro neurotoxicity of methylmercury, mercury, cadmium, and hydrogen peroxide on SH-SY5Y cells. J Vet Med Sci. 2019;81:828-837 pubmed publisher
Joshi D, Inamdar M. Rudhira/BCAS3 couples microtubules and intermediate filaments to promote cell migration for angiogenic remodeling. Mol Biol Cell. 2019;30:1437-1450 pubmed publisher
Pais S, Key C, Borges V, Pereira I, Gomes J, Fisher D, et al. CteG is a Chlamydia trachomatis effector protein that associates with the Golgi complex of infected host cells. Sci Rep. 2019;9:6133 pubmed publisher
Spits M, Janssen L, Voortman L, Kooij R, Neefjes A, Ovaa H, et al. Homeostasis of soluble proteins and the proteasome post nuclear envelope reformation in mitosis. J Cell Sci. 2019;132: pubmed publisher
Hua S, Vaughan B. In vitro comparison of liposomal drug delivery systems targeting the oxytocin receptor: a potential novel treatment for obstetric complications. Int J Nanomedicine. 2019;14:2191-2206 pubmed publisher
Gambarte Tudela J, Buonfigli J, Luján A, Alonso Bivou M, Cebrian I, Capmany A, et al. Rab39a and Rab39b Display Different Intracellular Distribution and Function in Sphingolipids and Phospholipids Transport. Int J Mol Sci. 2019;20: pubmed publisher
Moslehi M, Ng D, Bogoyevitch M. Pathogenic E2K mutation of doublecortin X (DCX) alters microtubule stabilisation and actin filament association. Biochem Biophys Res Commun. 2019;513:540-545 pubmed publisher
Klebanovych A, Sladkova V, Sulimenko T, Vosecká V, Capek M, Dráberová E, et al. Regulation of Microtubule Nucleation in Mouse Bone Marrow-Derived Mast Cells by Protein Tyrosine Phosphatase SHP-1. Cells. 2019;8: pubmed publisher
Tsygankova O, Keen J. A unique role for clathrin light chain A in cell spreading and migration. J Cell Sci. 2019;132: pubmed publisher
Bidaud Meynard A, Bossard F, Schnúr A, Fukuda R, Veit G, Xu H, et al. Transcytosis maintains CFTR apical polarity in the face of constitutive and mutation-induced basolateral missorting. J Cell Sci. 2019;132: pubmed publisher
Behera V, Stonestrom A, Hamagami N, Hsiung C, Keller C, Giardine B, et al. Interrogating Histone Acetylation and BRD4 as Mitotic Bookmarks of Transcription. Cell Rep. 2019;27:400-415.e5 pubmed publisher
Williamson C, Donaldson J. Arf6, JIP3, and dynein shape and mediate macropinocytosis. Mol Biol Cell. 2019;30:1477-1489 pubmed publisher
Alenquer M, Vale Costa S, Etibor T, Ferreira F, Sousa A, Amorim M. Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites. Nat Commun. 2019;10:1629 pubmed publisher
Ding X, Jiang X, Tian R, Zhao P, Li L, Wang X, et al. RAB2 regulates the formation of autophagosome and autolysosome in mammalian cells. Autophagy. 2019;:1-13 pubmed publisher
Tang S, Liu B, Liu M, Li Z, Liu J, Wang H, et al. Ionizing radiation-induced growth in soft agar is associated with miR-21 upregulation in wild-type and DNA double strand break repair deficient cells. DNA Repair (Amst). 2019;78:37-44 pubmed publisher
Tian Y, Wu Y, Liu L, He L, Gao J, Zhou L, et al. The structural characteristics of mononuclear-macrophage membrane observed by atomic force microscopy. J Struct Biol. 2019;206:314-321 pubmed publisher
Renkawitz J, Kopf A, Stopp J, de Vries I, Driscoll M, Merrin J, et al. Nuclear positioning facilitates amoeboid migration along the path of least resistance. Nature. 2019;568:546-550 pubmed publisher
Hauge S, Macurek L, Syljuåsen R. p21 limits S phase DNA damage caused by the Wee1 inhibitor MK1775. Cell Cycle. 2019;18:834-847 pubmed publisher
Wagai S, Kasamatsu A, Iyoda M, Hayashi F, Hiroshima K, Yoshimura S, et al. UNC93B1 promotes tumoral growth by controlling the secretion level of granulocyte macrophage colony-stimulating factor in human oral cancer. Biochem Biophys Res Commun. 2019;513:81-87 pubmed publisher
Griesche N, Sanchez G, Hermans C, Idevall Hagren O. Cortical mitochondria regulate insulin secretion by local Ca2+ buffering in rodent beta cells. J Cell Sci. 2019;132: pubmed publisher
Sweere J, Van Belleghem J, Ishak H, Bach M, Popescu M, Sunkari V, et al. Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection. Science. 2019;363: pubmed publisher
Muñoz S, Minamino M, Casas Delucchi C, Patel H, Uhlmann F. A Role for Chromatin Remodeling in Cohesin Loading onto Chromosomes. Mol Cell. 2019;74:664-673.e5 pubmed publisher
Dreval K, Lake R, Fan H. HDAC1 negatively regulates selective mitotic chromatin binding of the Notch effector RBPJ in a KDM5A-dependent manner. Nucleic Acids Res. 2019;47:4521-4538 pubmed publisher
Zinn A, Goicoechea S, Kreider Letterman G, Maity D, Awadia S, Cedeno Rosario L, et al. The small GTPase RhoG regulates microtubule-mediated focal adhesion disassembly. Sci Rep. 2019;9:5163 pubmed publisher
Lu G, Yi J, Gubas A, Wang Y, Wu Y, Ren Y, et al. Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation. Autophagy. 2019;:1-18 pubmed publisher
Li J, Gao W, Zhang Y, Cheng F, Eriksson J, Etienne Manneville S, et al. Engagement of vimentin intermediate filaments in hypotonic stress. J Cell Biochem. 2019;120:13168-13176 pubmed publisher
Dilshara M, Jayasooriya R, Karunarathne W, Choi Y, Kim G. Camptothecin induces mitotic arrest through Mad2-Cdc20 complex by activating the JNK-mediated Sp1 pathway. Food Chem Toxicol. 2019;127:143-155 pubmed publisher
Steinberger J, Robert F, Halle M, Williams D, Cencic R, Sawhney N, et al. Tracing MYC Expression for Small Molecule Discovery. Cell Chem Biol. 2019;26:699-710.e6 pubmed publisher
Aziz K, Limzerwala J, Sturmlechner I, Hurley E, Zhang C, Jeganathan K, et al. Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice. Gastroenterology. 2019;: pubmed publisher
Inaba H, Nomura R, Kato Y, Takeuchi H, Amano A, Asai F, et al. Adhesion and invasion of gingival epithelial cells by Porphyromonas gulae. PLoS ONE. 2019;14:e0213309 pubmed publisher
Bernard D, Mondesert O, Gomes A, Duthen Y, Lobjois V, Cussat Blanc S, et al. A checkpoint-oriented cell cycle simulation model. Cell Cycle. 2019;18:795-808 pubmed publisher
Arceci A, Bonacci T, Wang X, Stewart K, Damrauer J, Hoadley K, et al. FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer. Cell Rep. 2019;26:3076-3086.e6 pubmed publisher
Laflamme G, Sim S, Leary A, Pascariu M, Vogel J, D Amours D. Interphase Microtubules Safeguard Mitotic Progression by Suppressing an Aurora B-Dependent Arrest Induced by DNA Replication Stress. Cell Rep. 2019;26:2875-2889.e3 pubmed publisher
Uchida E, Suwa S, Yoshimoto R, Watanabe K, Kasama T, Miura O, et al. TOPK is regulated by PP2A and BCR/ABL in leukemia and enhances cell proliferation. Int J Oncol. 2019;54:1785-1796 pubmed publisher
Shimomura I, Yokoi A, Kohama I, Kumazaki M, Tada Y, Tatsumi K, et al. Drug library screen reveals benzimidazole derivatives as selective cytotoxic agents for KRAS-mutant lung cancer. Cancer Lett. 2019;451:11-22 pubmed publisher
Mascaraque M, Delgado Wicke P, Damian A, Lucena S, Carrasco E, Juarranz A. Mitotic Catastrophe Induced in HeLa Tumor Cells by Photodynamic Therapy with Methyl-aminolevulinate. Int J Mol Sci. 2019;20: pubmed publisher
Zhao P, Teng X, Tantirimudalige S, Nishikawa M, Wohland T, Toyama Y, et al. Aurora-A Breaks Symmetry in Contractile Actomyosin Networks Independently of Its Role in Centrosome Maturation. Dev Cell. 2019;48:631-645.e6 pubmed publisher
Su L, Zhou L, Chen F, Wang H, Qian H, Sheng Y, et al. Cideb controls sterol-regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites. EMBO J. 2019;38: pubmed publisher
Casler J, Papanikou E, Barrero J, Glick B. Maturation-driven transport and AP-1-dependent recycling of a secretory cargo in the Golgi. J Cell Biol. 2019;218:1582-1601 pubmed publisher
Li W, Wang H, Zhao X, Duan H, Cheng B, Liu Y, et al. A methylation-phosphorylation switch determines Plk1 kinase activity and function in DNA damage repair. Sci Adv. 2019;5:eaau7566 pubmed publisher
Zhang X, Chen W, Yin N, Dong L, Fu M, Zhan Q, et al. Regulation of OLC1 protein expression by the anaphase-promoting complex. Oncol Lett. 2019;17:2639-2646 pubmed publisher
Frank A, Ebersberger S, Fink A, Lampe S, Weigert A, Schmid T, et al. Apoptotic tumor cell-derived microRNA-375 uses CD36 to alter the tumor-associated macrophage phenotype. Nat Commun. 2019;10:1135 pubmed publisher
Bolomini Vittori M, Mennens S, Joosten B, Fransen J, Du G, van den Dries K, et al. PLD-dependent phosphatidic acid microdomains are signaling platforms for podosome formation. Sci Rep. 2019;9:3556 pubmed publisher
Ly P, Brunner S, Shoshani O, Kim D, Lan W, Pyntikova T, et al. Chromosome segregation errors generate a diverse spectrum of simple and complex genomic rearrangements. Nat Genet. 2019;51:705-715 pubmed publisher
Takahashi T, Nakagawa K, Tada S, Tsukamoto A. Low-energy shock waves evoke intracellular Ca2+ increases independently of sonoporation. Sci Rep. 2019;9:3218 pubmed publisher
Rozpedek W, Pytel D, Popławski T, Walczak A, Gradzik K, Wawrzynkiewicz A, et al. Inhibition of the PERK-Dependent Unfolded Protein Response Signaling Pathway Involved in the Pathogenesis of Alzheimer's Disease. Curr Alzheimer Res. 2019;16:209-218 pubmed publisher
Nishimura K, Johmura Y, Deguchi K, Jiang Z, Uchida K, Suzuki N, et al. Cdk1-mediated DIAPH1 phosphorylation maintains metaphase cortical tension and inactivates the spindle assembly checkpoint at anaphase. Nat Commun. 2019;10:981 pubmed publisher
Kim J, Kim J, Rhee K. PCNT is critical for the association and conversion of centrioles to centrosomes during mitosis. J Cell Sci. 2019;: pubmed publisher
Soares Cavalcante Costa V, Costa Reginaldo M, Queiroz Oliveira T, Silva Oliveira A, Couto N, Dos Anjos D, et al. Leishmania amazonensis hijacks host cell lysosomes involved in plasma membrane repair to induce invasion in fibroblasts. J Cell Sci. 2019;: pubmed publisher
Feng Y, Zhu R, Shen J, Wu J, Lu W, Zhang J, et al. Human Bone Marrow Mesenchymal Stem Cells Rescue Endothelial Cells Experiencing Chemotherapy Stress by Mitochondrial Transfer via Tunnelling Nanotubes. Stem Cells Dev. 2019;: pubmed publisher
Marín Rubio J, Perez Gomez E, Fernandez Piqueras J, Villa Morales M. S194-P-FADD as a marker of aggressiveness and poor prognosis in human T-cell lymphoblastic lymphoma. Carcinogenesis. 2019;: pubmed publisher
Klinkert K, Levernier N, Gross P, Gentili C, von Tobel L, Pierron M, et al. Aurora A depletion reveals centrosome-independent polarization mechanism in Caenorhabditis elegans. elife. 2019;8: pubmed publisher
Choi H, Zhu B. Upregulated Cyclin B1/CDK1 Mediates Apoptosis Following 2-Methoxyestradiol-Induced Mitotic Catastrophe: Role of Bcl-XL Phosphorylation. Steroids. 2019;: pubmed publisher
Garvin A, Walker A, Densham R, Chauhan A, Stone H, Mackay H, et al. The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms. Genes Dev. 2019;33:333-347 pubmed publisher
Smith W, Johnston D, Holmes S, Wensley H, Flavell S, Flavell D. Augmentation of Saporin-Based Immunotoxins for Human Leukaemia and Lymphoma Cells by Triterpenoid Saponins: The Modifying Effects of Small Molecule Pharmacological Agents. Toxins (Basel). 2019;11: pubmed publisher
Kamata H, Sadahiro S, Yamori T. Discovery of Inhibitors of Membrane Traffic from a Panel of Clinically Effective Anticancer Drugs. Biol Pharm Bull. 2019;42:814-818 pubmed publisher
Yang H, Zhang F, Huang C, Liao J, Han Y, Hao P, et al. Mps1 regulates spindle morphology through MCRS1 to promote chromosome alignment. Mol Biol Cell. 2019;30:1060-1068 pubmed publisher
Pachis S, Hiruma Y, Tromer E, Perrakis A, Kops G. Interactions between N-terminal Modules in MPS1 Enable Spindle Checkpoint Silencing. Cell Rep. 2019;26:2101-2112.e6 pubmed publisher
Lacefield C, Pnevmatikakis E, Paninski L, Bruno R. Reinforcement Learning Recruits Somata and Apical Dendrites across Layers of Primary Sensory Cortex. Cell Rep. 2019;26:2000-2008.e2 pubmed publisher
Wang Z, Gong Y, Peng B, Shi R, Fan D, Zhao H, et al. MRE11 UFMylation promotes ATM activation. Nucleic Acids Res. 2019;47:4124-4135 pubmed publisher
Izumi H, Li Y, Shibaki M, Mori D, Yasunami M, Sato S, et al. Recycling endosomal CD133 functions as an inhibitor of autophagy at the pericentrosomal region. Sci Rep. 2019;9:2236 pubmed publisher
Shi P, Wang Y, Huang Y, Zhang C, Li Y, Liu Y, et al. Arp2/3-branched actin regulates microtubule acetylation level and affects mitochondrial distribution. J Cell Sci. 2019;: pubmed publisher
Arriagada C, Luchsinger C, González A, Schwenke T, Arriagada G, Folch H, et al. The knocking down of the oncoprotein Golgi phosphoprotein 3 in T98G cells of glioblastoma multiforme disrupts cell migration by affecting focal adhesion dynamics in a focal adhesion kinase-dependent manner. PLoS ONE. 2019;14:e0212321 pubmed publisher
Vázquez Diez C, Paim L, FitzHarris G. Cell-Size-Independent Spindle Checkpoint Failure Underlies Chromosome Segregation Error in Mouse Embryos. Curr Biol. 2019;29:865-873.e3 pubmed publisher
Farías G, Fréal A, Tortosa E, Stucchi R, Pan X, Portegies S, et al. Feedback-Driven Mechanisms between Microtubules and the Endoplasmic Reticulum Instruct Neuronal Polarity. Neuron. 2019;102:184-201.e8 pubmed publisher
Ruan W, Venkatachalam G, Sobota R, Chen L, Wang L, Jacobson A, et al. Resistance to anti-microtubule drug-induced cell death is determined by regulation of BimEL expression. Oncogene. 2019;38:4352-4365 pubmed publisher
Li Y, Wang L, Zhang L, He Z, Feng G, Sun H, et al. Cyclin B3 is required for metaphase to anaphase transition in oocyte meiosis I. J Cell Biol. 2019;218:1553-1563 pubmed publisher
Kulkarni T, Tam A, Mukhopadhyay D, Bhattacharya S. AFM study: Cell cycle and probe geometry influences nanomechanical characterization of Panc1 cells. Biochim Biophys Acta Gen Subj. 2019;1863:802-812 pubmed publisher
Levasseur M, Thomas C, Davies O, Higgins J, Madgwick S. Aneuploidy in Oocytes Is Prevented by Sustained CDK1 Activity through Degron Masking in Cyclin B1. Dev Cell. 2019;48:672-684.e5 pubmed publisher
Kano F, Murata M. Phosphatidylinositol-3-phosphate-mediated actin domain formation linked to DNA synthesis upon insulin treatment in rat hepatoma-derived H4IIEC3 cells. Biochim Biophys Acta Mol Cell Res. 2019;1866:793-805 pubmed publisher
Masaki K, Sonobe Y, Ghadge G, Pytel P, Roos R. TDP-43 proteinopathy in Theiler's murine encephalomyelitis virus infection. PLoS Pathog. 2019;15:e1007574 pubmed publisher
Cheung M, Amin A, Wu R, Qin Y, Zou L, Yu Z, et al. Human NOC3 is essential for DNA replication licensing in human cells. Cell Cycle. 2019;18:605-620 pubmed publisher
Neurohr G, Terry R, Lengefeld J, Bonney M, Brittingham G, Moretto F, et al. Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence. Cell. 2019;: pubmed publisher
Goode D, Molliver D. Phospho-substrate profiling of Epac-dependent protein kinase C activity. Mol Cell Biochem. 2019;456:167-178 pubmed publisher
Sakaue H, Shiota T, Ishizaka N, Kawano S, Tamura Y, Tan K, et al. Porin Associates with Tom22 to Regulate the Mitochondrial Protein Gate Assembly. Mol Cell. 2019;73:1044-1055.e8 pubmed publisher
Haikala H, Anttila J, Marques E, Raatikainen T, Ilander M, Hakanen H, et al. Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy. Nat Commun. 2019;10:620 pubmed publisher
Wehrle A, Witkos T, Unger S, Schneider J, Follit J, Hermann J, et al. Hypomorphic mutations of TRIP11 cause odontochondrodysplasia. JCI Insight. 2019;4: pubmed publisher
Adriaans I, Basant A, Ponsioen B, Glotzer M, Lens S. PLK1 plays dual roles in centralspindlin regulation during cytokinesis. J Cell Biol. 2019;218:1250-1264 pubmed publisher
Li Z, Jiao X, Di Sante G, Ertel A, Casimiro M, Wang M, et al. Cyclin D1 integrates G9a-mediated histone methylation. Oncogene. 2019;38:4232-4249 pubmed publisher
Kreis N, Steinhäuser K, Ritter A, Klöble P, Hoock S, Roth S, et al. Potential involvement of RITA in the activation of Aurora A at spindle poles during mitosis. Oncogene. 2019;38:4199-4214 pubmed publisher
Jayanthan A, Hofmann B, Meier Stephenson V, Perinpanayagam M, Dunn S, Boklan J, et al. Targeted Polo-like Kinase Inhibition Combined With Aurora Kinase Inhibition in Pediatric Acute Leukemia Cells. J Pediatr Hematol Oncol. 2019;41:e359-e370 pubmed publisher
Biskou O, Casanova V, Hooper K, Kemp S, Wright G, Satsangi J, et al. The type III intermediate filament vimentin regulates organelle distribution and modulates autophagy. PLoS ONE. 2019;14:e0209665 pubmed publisher
Warchal S, Dawson J, Carragher N. Evaluation of Machine Learning Classifiers to Predict Compound Mechanism of Action When Transferred across Distinct Cell Lines. SLAS Discov. 2019;24:224-233 pubmed publisher
Zhang J, Wang Y, Zheng Z, Sun X, Chen T, Li C, et al. Intracellular ion and protein nanoparticle-induced osmotic pressure modify astrocyte swelling and brain edema in response to glutamate stimuli. Redox Biol. 2019;21:101112 pubmed publisher
Fang X, Yin H, Zhang H, Wu F, Liu Y, Fu Y, et al. p53 mediates hydroxyurea resistance in aneuploid cells of colon cancer. Exp Cell Res. 2019;376:39-48 pubmed publisher
Insinna C, Lu Q, Teixeira I, Harned A, Semler E, Stauffer J, et al. Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport. Nat Commun. 2019;10:428 pubmed publisher
Ocampo J, Chereji R, Eriksson P, Clark D. Contrasting roles of the RSC and ISW1/CHD1 chromatin remodelers in RNA polymerase II elongation and termination. Genome Res. 2019;: pubmed publisher
Sekiya T, Kato K, Kawaguchi A, Nagata K. Involvement of CTCF in transcription regulation of EGR1 at early G1 phase as an architecture factor. Sci Rep. 2019;9:329 pubmed publisher
Alfonso Pérez T, Hayward D, Holder J, Gruneberg U, Barr F. MAD1-dependent recruitment of CDK1-CCNB1 to kinetochores promotes spindle checkpoint signaling. J Cell Biol. 2019;218:1108-1117 pubmed publisher
Hayward D, Alfonso Pérez T, Cundell M, Hopkins M, Holder J, Bancroft J, et al. CDK1-CCNB1 creates a spindle checkpoint-permissive state by enabling MPS1 kinetochore localization. J Cell Biol. 2019;218:1182-1199 pubmed publisher
Dwivedi D, Kumari A, Rathi S, Mylavarapu S, Sharma M. The dynein adaptor Hook2 plays essential roles in mitotic progression and cytokinesis. J Cell Biol. 2019;: pubmed publisher
Jennings S, Ng H, Wang G. Establishment of a ΔF508-CF promyelocytic cell line for cystic fibrosis research and drug screening. J Cyst Fibros. 2019;18:44-53 pubmed publisher
Kurokawa S, Okuda A, Nishizawa Y, Furukawa K, Sumihiro A, Nakaji Y, et al. Suppression of cell cycle progression by poly(ADP-ribose) polymerase inhibitor PJ34 in neural stem/progenitor cells. Biochem Biophys Res Commun. 2019;510:59-64 pubmed publisher
Sharma P, Sen D, Neelakantan V, Shankar V, Jhunjhunwala S. Disparate effects of PEG or albumin based surface modification on the uptake of nano- and micro-particles. Biomater Sci. 2019;7:1411-1421 pubmed publisher
Ohno M, Ando T, Priest D, Kumar V, Yoshida Y, Taniguchi Y. Sub-nucleosomal Genome Structure Reveals Distinct Nucleosome Folding Motifs. Cell. 2019;176:520-534.e25 pubmed publisher
Lee J, Ismail A, Lee J, Zhou X, Materne E, Chodosh J, et al. Impact of dynamin 2 on adenovirus nuclear entry. Virology. 2019;529:43-56 pubmed publisher
Jiménez M, Urtasun R, Elizalde M, Azkona M, Latasa M, Uriarte I, et al. Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins. Nucleic Acids Res. 2019;47:3450-3466 pubmed publisher
Paonessa F, Evans L, Solanki R, Larrieu D, Wray S, Hardy J, et al. Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia. Cell Rep. 2019;26:582-593.e5 pubmed publisher
Takayama K, Suzuki Y, Yamamoto S, Obinata D, Takahashi S, Inoue S. Integrative Genomic Analysis of OCT1 Reveals Coordinated Regulation of Androgen Receptor in Advanced Prostate Cancer. Endocrinology. 2019;160:463-472 pubmed publisher
Fan P, Yang D, Wu J, Yang Y, Guo X, Tu J, et al. Cell-cycle-dependences of membrane permeability and viability observed for HeLa cells undergoing multi-bubble-cell interactions. Ultrason Sonochem. 2019;53:178-186 pubmed publisher
Witkos T, Chan W, Joensuu M, Rhiel M, Pallister E, Thomas Oates J, et al. GORAB scaffolds COPI at the trans-Golgi for efficient enzyme recycling and correct protein glycosylation. Nat Commun. 2019;10:127 pubmed publisher
Becker M, Dominguez M, Greune L, Soria Martinez L, Pfleiderer M, Schowalter R, et al. Infectious Entry of Merkel Cell Polyomavirus. J Virol. 2019;93: pubmed publisher
Guedes Dias P, Nirschl J, Abreu N, Tokito M, Janke C, Magiera M, et al. Kinesin-3 Responds to Local Microtubule Dynamics to Target Synaptic Cargo Delivery to the Presynapse. Curr Biol. 2019;29:268-282.e8 pubmed publisher
Rangaraju V, Lauterbach M, Schuman E. Spatially Stable Mitochondrial Compartments Fuel Local Translation during Plasticity. Cell. 2019;176:73-84.e15 pubmed publisher
Zatsepina O. Cytogenetic instability of chromosomal nucleolar organizer regions (NORs) in cloned mouse L929 fibroblasts. Chromosome Res. 2019;27:95-108 pubmed publisher
Sparks J, Chistol G, Gao A, Raschle M, Larsen N, Mann M, et al. The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair. Cell. 2019;176:167-181.e21 pubmed publisher
Liddiard K, Ruis B, Kan Y, Cleal K, Ashelford K, Hendrickson E, et al. DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase. Nucleic Acids Res. 2019;47:2402-2424 pubmed publisher
Nishibuchi G, Machida S, Nakagawa R, Yoshimura Y, Hiragami Hamada K, Abe Y, et al. Mitotic phosphorylation of HP1α regulates its cell cycle-dependent chromatin binding. J Biochem. 2019;165:433-446 pubmed publisher
Champion L, Pawar S, Luithle N, Ungricht R, Kutay U. Dissociation of membrane-chromatin contacts is required for proper chromosome segregation in mitosis. Mol Biol Cell. 2019;30:427-440 pubmed publisher
Hao X, Gu H, Chen C, Huang D, Zhao Y, Xie L, et al. Metabolic Imaging Reveals a Unique Preference of Symmetric Cell Division and Homing of Leukemia-Initiating Cells in an Endosteal Niche. Cell Metab. 2019;29:950-965.e6 pubmed publisher
Smyrek I, Mathew B, Fischer S, Lissek S, Becker S, Stelzer E. E-cadherin, actin, microtubules and FAK dominate different spheroid formation phases and important elements of tissue integrity. Biol Open. 2019;8: pubmed publisher
Mohan N, Sorokina E, Verdeny I, Alvarez A, Lakadamyali M. Detyrosinated microtubules spatially constrain lysosomes facilitating lysosome-autophagosome fusion. J Cell Biol. 2019;218:632-643 pubmed publisher
Sallé J, Xie J, Ershov D, Lacassin M, Dmitrieff S, Minc N. Asymmetric division through a reduction of microtubule centering forces. J Cell Biol. 2019;218:771-782 pubmed publisher
Vasjari L, Bresan S, Biskup C, Pai G, Rubio I. Ras signals principally via Erk in G1 but cooperates with PI3K/Akt for Cyclin D induction and S-phase entry. Cell Cycle. 2019;18:204-225 pubmed publisher
Makhoul C, Gosavi P, Duffield R, Delbridge B, Williamson N, Gleeson P. Intersectin-1 interacts with the golgin GCC88 to couple the actin network and Golgi architecture. Mol Biol Cell. 2019;30:370-386 pubmed publisher
Lafarga V, Sung H, Haneke K, Roessig L, Pauleau A, Bruer M, et al. TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress. EMBO Rep. 2019;20: pubmed publisher
Hua S. Synthesis and in vitro characterization of oxytocin receptor targeted PEGylated immunoliposomes for drug delivery to the uterus. J Liposome Res. 2019;29:357-367 pubmed publisher
Hägele S, Muller A, Nusshag C, Reiser J, Zeier M, Krautkrämer E. Virus- and cell type-specific effects in orthohantavirus infection. Virus Res. 2019;260:102-113 pubmed publisher
Bressy C, Droby G, Maldonado B, Steuerwald N, Grdzelishvili V. Cell Cycle Arrest in G2/M Phase Enhances Replication of Interferon-Sensitive Cytoplasmic RNA Viruses via Inhibition of Antiviral Gene Expression. J Virol. 2019;93: pubmed publisher
Antonucci L, Di Magno L, D Amico D, Manni S, Serrao S, Di Pastena F, et al. Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation. Int J Oncol. 2019;54:505-514 pubmed publisher
Li Y, Kokura K, Inoue T. Stabilization of P/CAF, as a ubiquitin ligase toward MDM2, suppresses mitotic cell death through p53-p21 activation in HCT116 cells with SIRT2 suppression. Biochem Biophys Res Commun. 2019;508:230-236 pubmed publisher
Genoyer E, LOPEZ C. Defective Viral Genomes Alter How Sendai Virus Interacts with Cellular Trafficking Machinery, Leading to Heterogeneity in the Production of Viral Particles among Infected Cells. J Virol. 2019;93: pubmed publisher
Moran K, Kang H, Araujo A, Zyla T, Saito K, Tsygankov D, et al. Cell-cycle control of cell polarity in yeast. J Cell Biol. 2019;218:171-189 pubmed publisher
Hamann A, Broad K, Nguyen A, Pannier A. Mechanisms of unprimed and dexamethasone-primed nonviral gene delivery to human mesenchymal stem cells. Biotechnol Bioeng. 2019;116:427-443 pubmed publisher
Bajzikova M, Kovarova J, Coelho A, Boukalova S, Oh S, Rohlenova K, et al. Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells. Cell Metab. 2019;29:399-416.e10 pubmed publisher
Planques A, Malem J, Parapar J, Vervoort M, Gazave E. Morphological, cellular and molecular characterization of posterior regeneration in the marine annelid Platynereis dumerilii. Dev Biol. 2019;445:189-210 pubmed publisher
Gong Z, Fang C, You R, Shao X, Wei X, Chang R, et al. Distinct relaxation timescales of neurites revealed by rate-dependent indentation, relaxation and micro-rheology tests. Soft Matter. 2019;15:166-174 pubmed publisher
Wang L, Lee Y, Huang C, Shi Y, Chen Y, Pei S, et al. Non-mitotic effect of albendazole triggers apoptosis of human leukemia cells via SIRT3/ROS/p38 MAPK/TTP axis-mediated TNF-α upregulation. Biochem Pharmacol. 2019;162:154-168 pubmed publisher
Tan Z, Chan Y, Chua Y, Rutledge S, Pavelka N, Cimini D, et al. Environmental stresses induce karyotypic instability in colorectal cancer cells. Mol Biol Cell. 2019;30:42-55 pubmed publisher
Oser M, Fonseca R, Chakraborty A, Brough R, Spektor A, Jennings R, et al. Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival. Cancer Discov. 2019;9:230-247 pubmed publisher
Werwein E, Cibis H, Hess D, Klempnauer K. Activation of the oncogenic transcription factor B-Myb via multisite phosphorylation and prolyl cis/trans isomerization. Nucleic Acids Res. 2019;47:103-121 pubmed publisher
Ashley N, Ouaret D, Bodmer W. Cellular polarity modulates drug resistance in primary colorectal cancers via orientation of the multidrug resistance protein ABCB1. J Pathol. 2019;247:293-304 pubmed publisher
Meyer S, Dunn M, Vidler D, Porter A, Blain P, Jowsey P. Phosphorylation of MCPH1 isoforms during mitosis followed by isoform-specific degradation by APC/C-CDH1. FASEB J. 2019;33:2796-2808 pubmed publisher
Li L, Yang J, Wang J, Kopecek J. Drug-free macromolecular therapeutics exhibit amplified apoptosis in G2/M phase arrested cells. J Drug Target. 2019;27:566-572 pubmed publisher
Carvajal Maldonado D, Byrum A, Jackson J, Wessel S, Lema on D, Guitton Sert L, et al. Perturbing cohesin dynamics drives MRE11 nuclease-dependent replication fork slowing. Nucleic Acids Res. 2019;47:1294-1310 pubmed publisher
Macquart C, Jüttner R, Morales Rodriguez B, Le Dour C, Lefebvre F, Chatzifrangkeskou M, et al. Microtubule cytoskeleton regulates Connexin 43 localization and cardiac conduction in cardiomyopathy caused by mutation in A-type lamins gene. Hum Mol Genet. 2019;28:4043-4052 pubmed publisher
Antúnez Mojica M, Rojas Sepúlveda A, Mendieta Serrano M, González Maya L, Marquina S, Salas Vidal E, et al. Lignans from Bursera fagaroides Affect In Vivo Cell Behavior by Disturbing the Tubulin Cytoskeleton in Zebrafish Embryos. Molecules. 2018;24: pubmed publisher
Tvorogova A, Saidova A, Smirnova T, Vorobjev I. Dynamic microtubules drive fibroblast spreading. Biol Open. 2018;7: pubmed publisher
Simula L, Pacella I, Colamatteo A, Procaccini C, Cancila V, Bordi M, et al. Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming. Cell Rep. 2018;25:3059-3073.e10 pubmed publisher
Schell C, Sabass B, Helmstaedter M, Geist F, Abed A, Yasuda Yamahara M, et al. ARP3 Controls the Podocyte Architecture at the Kidney Filtration Barrier. Dev Cell. 2018;47:741-757.e8 pubmed publisher
Karole A, Chodisetty S, Ali A, Kumari N, Tyagi S. Novel sub-cellular localizations and intra-molecular interactions may define new functions of Mixed Lineage Leukemia protein. Cell Cycle. 2018;17:2684-2696 pubmed publisher
Wild T, Budzowska M, Hellmuth S, Eibes S, Karemore G, Barisic M, et al. Deletion of APC7 or APC16 Allows Proliferation of Human Cells without the Spindle Assembly Checkpoint. Cell Rep. 2018;25:2317-2328.e5 pubmed publisher
Subramanian A, Kanzaki L, Galloway J, Schilling T. Mechanical force regulates tendon extracellular matrix organization and tenocyte morphogenesis through TGFbeta signaling. elife. 2018;7: pubmed publisher
Lee H, Jung Y, Oh J, Choi G, Chae C, Kim J, et al. BICD1 mediates HIF1α nuclear translocation in mesenchymal stem cells during hypoxia adaptation. Cell Death Differ. 2018;: pubmed publisher
Krol K, Antoniuk Majchrzak J, Skoneczny M, Sieńko M, Jendrysek J, Rumienczyk I, et al. Lack of G1/S control destabilizes the yeast genome via replication stress-induced DSBs and illegitimate recombination. J Cell Sci. 2018;131: pubmed publisher
Doster R, Sutton J, Rogers L, Aronoff D, Gaddy J. Streptococcus agalactiae Induces Placental Macrophages To Release Extracellular Traps Loaded with Tissue Remodeling Enzymes via an Oxidative Burst-Dependent Mechanism. MBio. 2018;9: pubmed publisher
Dang T, Jang S, Back S, Park J, Han I. DRG2 Deficiency Causes Impaired Microtubule Dynamics in HeLa Cells. Mol Cells. 2018;41:1045-1051 pubmed publisher
Bakos G, Yu L, Gak I, Roumeliotis T, Liakopoulos D, Choudhary J, et al. An E2-ubiquitin thioester-driven approach to identify substrates modified with ubiquitin and ubiquitin-like molecules. Nat Commun. 2018;9:4776 pubmed publisher
Rodriguez Rodriguez J, Lewis C, McKinley K, Sikirzhytski V, Corona J, Maciejowski J, et al. Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion. Curr Biol. 2018;28:3422-3429.e5 pubmed publisher
Pereira C, Reis R, Gama J, Celestino R, Cheerambathur D, Carvalho A, et al. Self-Assembly of the RZZ Complex into Filaments Drives Kinetochore Expansion in the Absence of Microtubule Attachment. Curr Biol. 2018;28:3408-3421.e8 pubmed publisher
Lee J, Ha G, Kim H, Lee C. Oncogenic potential of BEX4 is conferred by Polo-like kinase 1-mediated phosphorylation. Exp Mol Med. 2018;50:138 pubmed publisher
Daou S, Barbour H, Ahmed O, Masclef L, Baril C, Sen Nkwe N, et al. Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1. Nat Commun. 2018;9:4385 pubmed publisher
Simões Sousa S, Littler S, Thompson S, Minshall P, Whalley H, Bakker B, et al. The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α. Cell Rep. 2018;25:749-760.e6 pubmed publisher
Xu C, Ai D, Suo S, Chen X, Yan Y, Cao Y, et al. Accurate Drug Repositioning through Non-tissue-Specific Core Signatures from Cancer Transcriptomes. Cell Rep. 2018;25:523-535.e5 pubmed publisher
Tabdanov E, Puram V, Zhovmer A, Provenzano P. Microtubule-Actomyosin Mechanical Cooperation during Contact Guidance Sensing. Cell Rep. 2018;25:328-338.e5 pubmed publisher
Glen C, McDevitt T, Kemp M. Dynamic intercellular transport modulates the spatial patterning of differentiation during early neural commitment. Nat Commun. 2018;9:4111 pubmed publisher
Wei Z, Greaney J, Zhou C, A Homer H. Cdk1 inactivation induces post-anaphase-onset spindle migration and membrane protrusion required for extreme asymmetry in mouse oocytes. Nat Commun. 2018;9:4029 pubmed publisher
Romero M, McCathie G, Jankun P, Roehl H. Damage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of Hedgehog expressing cells. Nat Commun. 2018;9:4010 pubmed publisher
Stadler L, Speckner K, Weiss M. Diffusion of Exit Sites on the Endoplasmic Reticulum: A Random Walk on a Shivering Backbone. Biophys J. 2018;115:1552-1560 pubmed publisher
Pieuchot L, Marteau J, Guignandon A, Dos Santos T, Brigaud I, Chauvy P, et al. Curvotaxis directs cell migration through cell-scale curvature landscapes. Nat Commun. 2018;9:3995 pubmed publisher
Feringa F, Raaijmakers J, Hadders M, Vaarting C, Macurek L, Heitink L, et al. Persistent repair intermediates induce senescence. Nat Commun. 2018;9:3923 pubmed publisher
Lee H, Lin Z, Chae S, Yoo Y, Kim B, Lee Y, et al. The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation. Nat Commun. 2018;9:3848 pubmed publisher
Soliman M, Kim D, Kim C, Seo J, Kim J, Park J, et al. Porcine sapovirus Cowden strain enters LLC-PK cells via clathrin- and cholesterol-dependent endocytosis with the requirement of dynamin II. Vet Res. 2018;49:92 pubmed publisher
Plaud C, Joshi V, Kajevu N, Poüs C, Curmi P, Burgo A. Functional differences of short and long isoforms of spastin harboring missense mutation. Dis Model Mech. 2018;11: pubmed publisher
Shoaib M, Walter D, Gillespie P, Izard F, Fahrenkrog B, Lleres D, et al. Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing. Nat Commun. 2018;9:3704 pubmed publisher
Wang H, Qiu Z, Liu B, Wu Y, Ren J, Liu Y, et al. PLK1 targets CtIP to promote microhomology-mediated end joining. Nucleic Acids Res. 2018;46:10724-10739 pubmed publisher
Lång E, Połeć A, Lang A, Valk M, Blicher P, Rowe A, et al. Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding. Nat Commun. 2018;9:3665 pubmed publisher
Carrasco Garcia E, Martinez Lacaci I, Mayor López L, Tristante E, Carballo Santana M, Garcia Morales P, et al. PDGFR and IGF-1R Inhibitors Induce a G2/M Arrest and Subsequent Cell Death in Human Glioblastoma Cell Lines. Cells. 2018;7: pubmed publisher
Ha G, Lee C, Kim C. Development of a Novel Nonradioisotopic Assay and Cdc25B Overexpression Cell Lines for Use in Screening for Cdc25B Inhibitors. Yonsei Med J. 2018;59:995-1003 pubmed publisher
Heinrich B, Maliga Z, Stein D, Hyman A, Whelan S. Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments. MBio. 2018;9: pubmed publisher
Pesenti M, Prumbaum D, Auckland P, Smith C, Faesen A, Petrovic A, et al. Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80. Mol Cell. 2018;71:923-939.e10 pubmed publisher
Suzuki A, Gupta A, Long S, Evans R, Badger B, Salmon E, et al. A Kinesin-5, Cin8, Recruits Protein Phosphatase 1 to Kinetochores and Regulates Chromosome Segregation. Curr Biol. 2018;28:2697-2704.e3 pubmed publisher
Wang Z, Wang Y, Wang S, Meng X, Song F, Huo W, et al. Coxsackievirus A6 Induces Cell Cycle Arrest in G0/G1 Phase for Viral Production. Front Cell Infect Microbiol. 2018;8:279 pubmed publisher
Thomas H, Zhang Y, Stefely J, Veiga S, Thomas G, Kozma S, et al. Mitochondrial Complex I Activity Is Required for Maximal Autophagy. Cell Rep. 2018;24:2404-2417.e8 pubmed publisher
Uetake Y, Sluder G. Activation of the apoptotic pathway during prolonged prometaphase blocks daughter cell proliferation. Mol Biol Cell. 2018;29:2632-2643 pubmed publisher
Arbach H, Harland Dunaway M, Chang J, Wills A. Extreme nuclear branching in healthy epidermal cells of the Xenopus tail fin. J Cell Sci. 2018;131: pubmed publisher
Kang H, Song H, Ahmed M, Guo Y, Zhang M, Chen C, et al. NQO1 regulates mitotic progression and response to mitotic stress through modulating SIRT2 activity. Free Radic Biol Med. 2018;126:358-371 pubmed publisher
Kim S, Lee Y, Tasaki T, Mun S, Hwang J, Kang M, et al. The N-recognin UBR4 of the N-end rule pathway is targeted to and required for the biogenesis of the early endosome. J Cell Sci. 2018;131: pubmed publisher
Kalimutho M, Sinha D, Jeffery J, Nones K, Srihari S, Fernando W, et al. CEP55 is a determinant of cell fate during perturbed mitosis in breast cancer. EMBO Mol Med. 2018;10: pubmed publisher
Evrin C, Maman J, Diamante A, Pellegrini L, Labib K. Histone H2A-H2B binding by Pol ? in the eukaryotic replisome contributes to the maintenance of repressive chromatin. EMBO J. 2018;: pubmed publisher
Colin A, Singaravelu P, Thery M, Blanchoin L, Gueroui Z. Actin-Network Architecture Regulates Microtubule Dynamics. Curr Biol. 2018;: pubmed publisher
Almeida F, Luís M, Pereira I, Pais S, Mota L. The Human Centrosomal Protein CCDC146 Binds Chlamydia trachomatis Inclusion Membrane Protein CT288 and Is Recruited to the Periphery of the Chlamydia-Containing Vacuole. Front Cell Infect Microbiol. 2018;8:254 pubmed publisher
Dogra N, Kumar A, Mukhopadhyay T. Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways. Sci Rep. 2018;8:11926 pubmed publisher
Tang F, Pan M, Lu Y, Wan X, Zhang Y, Sun S. Involvement of Kif4a in Spindle Formation and Chromosome Segregation in Mouse Oocytes. Aging Dis. 2018;9:623-633 pubmed publisher
Jemaà M, Abassi Y, Kifagi C, Fezai M, Daams R, Lang F, et al. Reversine inhibits Colon Carcinoma Cell Migration by Targeting JNK1. Sci Rep. 2018;8:11821 pubmed publisher
Dong R, Zhu T, Benedetti L, Gowrishankar S, Deng H, Cai Y, et al. The inositol 5-phosphatase INPP5K participates in the fine control of ER organization. J Cell Biol. 2018;217:3577-3592 pubmed publisher
Greenan G, Keszthelyi B, Vale R, Agard D. Insights into centriole geometry revealed by cryotomography of doublet and triplet centrioles. elife. 2018;7: pubmed publisher
Novais Cruz M, Alba Abad M, van IJcken W, Galjart N, Jeyaprakash A, Maiato H, et al. Mitotic progression, arrest, exit or death relies on centromere structural integrity, rather than de novo transcription. elife. 2018;7: pubmed publisher
Tanimoto H, Sallé J, Dodin L, Minc N. Physical Forces Determining the Persistency and Centering Precision of Microtubule Asters. Nat Phys. 2018;14:848-854 pubmed publisher
Ho Y, Shishkova E, Hose J, Coon J, Gasch A. Decoupling Yeast Cell Division and Stress Defense Implicates mRNA Repression in Translational Reallocation during Stress. Curr Biol. 2018;28:2673-2680.e4 pubmed publisher
Gut G, Herrmann M, Pelkmans L. Multiplexed protein maps link subcellular organization to cellular states. Science. 2018;361: pubmed publisher
Lawrence R, Cho K, Rappold R, Thrun A, Tofaute M, Kim D, et al. A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold. Nat Cell Biol. 2018;20:1052-1063 pubmed publisher
Amini P, Stojkov D, Felser A, Jackson C, Courage C, Schaller A, et al. Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nat Commun. 2018;9:2958 pubmed publisher
Singh V, Erady C, Balasubramanian N. Cell-matrix adhesion controls Golgi organization and function through Arf1 activation in anchorage-dependent cells. J Cell Sci. 2018;131: pubmed publisher
Mutalik S, Joseph J, Pullarkat P, Ghose A. Cytoskeletal Mechanisms of Axonal Contractility. Biophys J. 2018;115:713-724 pubmed publisher
Brzek A, Cichocka M, Dolata J, Juzwa W, Schumperli D, Raczynska K. Positive cofactor 4 (PC4) contributes to the regulation of replication-dependent canonical histone gene expression. BMC Mol Biol. 2018;19:9 pubmed publisher
Zhang H, Hu J, Fu R, Liu X, Zhang Y, Li J, et al. Flavonoids inhibit cell proliferation and induce apoptosis and autophagy through downregulation of PI3K? mediated PI3K/AKT/mTOR/p70S6K/ULK signaling pathway in human breast cancer cells. Sci Rep. 2018;8:11255 pubmed publisher
Gong X, Didan Y, Lock J, Stromblad S. KIF13A-regulated RhoB plasma membrane localization governs membrane blebbing and blebby amoeboid cell migration. EMBO J. 2018;37: pubmed publisher
Boutin M, Voss T, Titus S, Cruz Gutierrez K, Michael S, Ferrer M. A high-throughput imaging and nuclear segmentation analysis protocol for cleared 3D culture models. Sci Rep. 2018;8:11135 pubmed publisher
Eisler S, Curado F, Link G, Schulz S, Noack M, Steinke M, et al. A Rho signaling network links microtubules to PKD controlled carrier transport to focal adhesions. elife. 2018;7: pubmed publisher
Kahn O, Schätzle P, van de Willige D, Tas R, Lindhout F, Portegies S, et al. APC2 controls dendrite development by promoting microtubule dynamics. Nat Commun. 2018;9:2773 pubmed publisher
Akram S, Yang F, Li J, Adams G, Liu Y, Zhuang X, et al. LRIF1 interacts with HP1α to coordinate accurate chromosome segregation during mitosis. J Mol Cell Biol. 2018;10:527-538 pubmed publisher
Qiang L, Sun X, Austin T, Muralidharan H, Jean D, Liu M, et al. Tau Does Not Stabilize Axonal Microtubules but Rather Enables Them to Have Long Labile Domains. Curr Biol. 2018;28:2181-2189.e4 pubmed publisher
Ohkawa T, Welch M. Baculovirus Actin-Based Motility Drives Nuclear Envelope Disruption and Nuclear Egress. Curr Biol. 2018;28:2153-2159.e4 pubmed publisher
Petty E, Evpak M, Pillus L. Connecting GCN5's centromeric SAGA to the mitotic tension-sensing checkpoint. Mol Biol Cell. 2018;29:2201-2212 pubmed publisher
Meriin A, Narayanan A, Meng L, Alexandrov I, Varelas X, Cisse I, et al. Hsp70-Bag3 complex is a hub for proteotoxicity-induced signaling that controls protein aggregation. Proc Natl Acad Sci U S A. 2018;115:E7043-E7052 pubmed publisher
Pavlaki I, Docquier F, Chernukhin I, Kita G, Gretton S, Clarkson C, et al. Poly(ADP-ribosyl)ation associated changes in CTCF-chromatin binding and gene expression in breast cells. Biochim Biophys Acta Gene Regul Mech. 2018;1861:718-730 pubmed publisher
Kok Y, Schmutz S, Inderbitzin A, Neumann K, Kelley A, Jörimann L, et al. Spontaneous reactivation of latent HIV-1 promoters is linked to the cell cycle as revealed by a genetic-insulators-containing dual-fluorescence HIV-1-based vector. Sci Rep. 2018;8:10204 pubmed publisher
Colburn Z, Jones J. Complexes of α6β4 integrin and vimentin act as signaling hubs to regulate epithelial cell migration. J Cell Sci. 2018;131: pubmed publisher
Adam K, Cartel M, Lambert M, David L, Yuan L, Besson A, et al. A PIM-CHK1 signaling pathway regulates PLK1 phosphorylation and function during mitosis. J Cell Sci. 2018;131: pubmed publisher
Szczepanski A, Owczarek K, Milewska A, Baster Z, Rajfur Z, Mitchell J, et al. Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells. Vet Res. 2018;49:55 pubmed publisher
Cabe M, Rademacher D, Karlsson A, Cherukuri S, Bakowska J. PB1 and UBA domains of p62 are essential for aggresome-like induced structure formation. Biochem Biophys Res Commun. 2018;503:2306-2311 pubmed publisher
Zulkipli I, Clark J, Hart M, Shrestha R, Gul P, Dang D, et al. Spindle rotation in human cells is reliant on a MARK2-mediated equatorial spindle-centering mechanism. J Cell Biol. 2018;217:3057-3070 pubmed publisher
Cohignac V, Landry M, Ridoux A, Pinault M, Annangi B, Gerdil A, et al. Carbon nanotubes, but not spherical nanoparticles, block autophagy by a shape-related targeting of lysosomes in murine macrophages. Autophagy. 2018;14:1323-1334 pubmed publisher
Petela N, Gligoris T, Metson J, Lee B, Voulgaris M, Hu B, et al. Scc2 Is a Potent Activator of Cohesin's ATPase that Promotes Loading by Binding Scc1 without Pds5. Mol Cell. 2018;70:1134-1148.e7 pubmed publisher
Wynne C, Vallee R. Cdk1 phosphorylation of the dynein adapter Nde1 controls cargo binding from G2 to anaphase. J Cell Biol. 2018;217:3019-3029 pubmed publisher
Ivanov M, Ladurner R, Poser I, Beveridge R, Rampler E, Hudecz O, et al. The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion. EMBO J. 2018;37: pubmed publisher
Xu W, Alizadeh E, Prasad A. Force Spectrum Microscopy Using Mitochondrial Fluctuations of Control and ATP-Depleted Cells. Biophys J. 2018;114:2933-2944 pubmed publisher
Sacristan C, Ahmad M, Keller J, Fermie J, Groenewold V, Tromer E, et al. Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis. Nat Cell Biol. 2018;20:800-810 pubmed publisher
Fuchs R, Stracke A, Holzmann V, Luschin Ebengreuth G, Meier Allard N, Ebner N, et al. Prazosin induced lysosomal tubulation interferes with cytokinesis and the endocytic sorting of the tumour antigen CD98hc. Biochim Biophys Acta Mol Cell Res. 2018;1865:1211-1229 pubmed publisher
Sikirzhytski V, Renda F, Tikhonenko I, Magidson V, McEwen B, Khodjakov A. Microtubules assemble near most kinetochores during early prometaphase in human cells. J Cell Biol. 2018;217:2647-2659 pubmed publisher
Winkler C, Rouget R, Wu D, Beullens M, Van Eynde A, Bollen M. Overexpression of PP1-NIPP1 limits the capacity of cells to repair DNA double-strand breaks. J Cell Sci. 2018;131: pubmed publisher
Künzel U, Grieve A, Meng Y, Sieber B, Cowley S, Freeman M. FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex. elife. 2018;7: pubmed publisher
Schott K, Fuchs N, Derua R, Mahboubi B, Schnellbächer E, Seifried J, et al. Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit. Nat Commun. 2018;9:2227 pubmed publisher
Hall A, Anderson C, Smith J, Mirshahi T, Elayi C, January C, et al. Visualizing Mutation-Specific Differences in the Trafficking-Deficient Phenotype of Kv11.1 Proteins Linked to Long QT Syndrome Type 2. Front Physiol. 2018;9:584 pubmed publisher
Obrist F, Michels J, Durand S, Chery A, Pol J, Levesque S, et al. Metabolic vulnerability of cisplatin-resistant cancers. EMBO J. 2018;37: pubmed publisher
Ritt M, Sivaramakrishnan S. Engaging myosin VI tunes motility, morphology and identity in endocytosis. Traffic. 2018;: pubmed publisher
Walton Z, Patel C, Brooks R, Yu Y, Ibrahim Hashim A, Riddle M, et al. Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR. Cell. 2018;174:72-87.e32 pubmed publisher
Cervia L, Chang C, Wang L, Mao M, Yuan F. Enhancing Electrotransfection Efficiency through Improvement in Nuclear Entry of Plasmid DNA. Mol Ther Nucleic Acids. 2018;11:263-271 pubmed publisher
Sawai Y, Kasamatsu A, Nakashima D, Fushimi K, Kasama H, Iyoda M, et al. Critical role of deoxynucleotidyl transferase terminal interacting protein 1 in oral cancer. Lab Invest. 2018;98:980-988 pubmed publisher
Park B, Oh S, Jo S, Kang D, Lim J, Jung Y, et al. Determination of the molecular assembly of actin and actin-binding proteins using photoluminescence. Colloids Surf B Biointerfaces. 2018;169:462-469 pubmed publisher
Palma A, Pugliese G, Murfuni I, Marabitti V, Malacaria E, Rinalducci S, et al. Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress. Nucleic Acids Res. 2018;46:5109-5124 pubmed publisher
Thatte J, Massimi P, Thomas M, Boon S, Banks L. The Human Papillomavirus E6 PDZ Binding Motif Links DNA Damage Response Signaling to E6 Inhibition of p53 Transcriptional Activity. J Virol. 2018;92: pubmed publisher
Okumura M, Natsume T, Kanemaki M, Kiyomitsu T. Dynein-Dynactin-NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble. elife. 2018;7: pubmed publisher
Jurášek M, Cernohorská M, Rehulka J, Spiwok V, Sulimenko T, Dráberová E, et al. Estradiol dimer inhibits tubulin polymerization and microtubule dynamics. J Steroid Biochem Mol Biol. 2018;183:68-79 pubmed publisher
Leiva Rodríguez T, Romeo Guitart D, Marmolejo Martínez Artesero S, Herrando Grabulosa M, Bosch A, Forés J, et al. ATG5 overexpression is neuroprotective and attenuates cytoskeletal and vesicle-trafficking alterations in axotomized motoneurons. Cell Death Dis. 2018;9:626 pubmed publisher
Dudka D, Noatynska A, Smith C, Liaudet N, McAinsh A, Meraldi P. Complete microtubule-kinetochore occupancy favours the segregation of merotelic attachments. Nat Commun. 2018;9:2042 pubmed publisher
Krastev D, Pettitt S, Campbell J, Song F, Tanos B, Stoynov S, et al. Coupling bimolecular PARylation biosensors with genetic screens to identify PARylation targets. Nat Commun. 2018;9:2016 pubmed publisher
Kettenbach A, Schlosser K, Lyons S, Nasa I, Gui J, Adamo M, et al. Global assessment of its network dynamics reveals that the kinase Plk1 inhibits the phosphatase PP6 to promote Aurora A activity. Sci Signal. 2018;11: pubmed publisher
Murthy T, Bluemn T, Gupta A, Reimer M, Rao S, Pillai M, et al. Cyclin-dependent kinase 1 (CDK1) and CDK2 have opposing roles in regulating interactions of splicing factor 3B1 with chromatin. J Biol Chem. 2018;293:10220-10234 pubmed publisher
Fu H, Gao H, Qi X, Zhao L, Wu D, Bai Y, et al. Aldolase A promotes proliferation and G1/S transition via the EGFR/MAPK pathway in non-small cell lung cancer. Cancer Commun (Lond). 2018;38:18 pubmed publisher
Eot Houllier G, Magnaghi Jaulin L, Fulcrand G, Moyroud F, Monier S, Jaulin C. Aurora A-dependent CENP-A phosphorylation at inner centromeres protects bioriented chromosomes against cohesion fatigue. Nat Commun. 2018;9:1888 pubmed publisher
Ochocki J, Khare S, Hess M, Ackerman D, Qiu B, Daisak J, et al. Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity. Cell Metab. 2018;27:1263-1280.e6 pubmed publisher
Srinivasan M, Scheinost J, Petela N, Gligoris T, Wissler M, Ogushi S, et al. The Cohesin Ring Uses Its Hinge to Organize DNA Using Non-topological as well as Topological Mechanisms. Cell. 2018;173:1508-1519.e18 pubmed publisher
Betleja E, Nanjundappa R, Cheng T, Mahjoub M. A novel Cep120-dependent mechanism inhibits centriole maturation in quiescent cells. elife. 2018;7: pubmed publisher
Li F, Kim H, Ji Z, Zhang T, Chen B, Ge Y, et al. The BUB3-BUB1 Complex Promotes Telomere DNA Replication. Mol Cell. 2018;70:395-407.e4 pubmed publisher
Wolf P, Cuba Ramos A, Kenzel J, Neumann B, Stemmann O. Studying meiotic cohesin in somatic cells reveals that Rec8-containing cohesin requires Stag3 to function and is regulated by Wapl and sororin. J Cell Sci. 2018;131: pubmed publisher
Hossain D, Ferreira Barbosa J, Cohen E, Tsang W. HIV-1 Vpr hijacks EDD-DYRK2-DDB1DCAF1 to disrupt centrosome homeostasis. J Biol Chem. 2018;293:9448-9460 pubmed publisher
Eno C, Pelegri F. Modulation of F-actin dynamics by maternal Mid1ip1L controls germ plasm aggregation and furrow recruitment in the zebrafish embryo. Development. 2018;145: pubmed publisher
Sipos A, Kim K, Chow R, Flodby P, Borok Z, Crandall E. Alveolar epithelial cell processing of nanoparticles activates autophagy and lysosomal exocytosis. Am J Physiol Lung Cell Mol Physiol. 2018;315:L286-L300 pubmed publisher
Tosetti F, Vené R, Camodeca C, Nuti E, Rossello A, D Arrigo C, et al. Specific ADAM10 inhibitors localize in exosome-like vesicles released by Hodgkin lymphoma and stromal cells and prevent sheddase activity carried to bystander cells. Oncoimmunology. 2018;7:e1421889 pubmed publisher
Bøe C, Håland T, Boye E, Syljuåsen R, Grallert B. A novel role for ATR/Rad3 in G1 phase. Sci Rep. 2018;8:6880 pubmed publisher
Yaguchi K, Yamamoto T, Matsui R, Tsukada Y, Shibanuma A, Kamimura K, et al. Uncoordinated centrosome cycle underlies the instability of non-diploid somatic cells in mammals. J Cell Biol. 2018;217:2463-2483 pubmed publisher
Sepúlveda G, Antkowiak M, Brust Mascher I, Mahe K, Ou T, Castro N, et al. Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates. elife. 2018;7: pubmed publisher
Becher I, Andrés Pons A, Romanov N, Stein F, Schramm M, Baudin F, et al. Pervasive Protein Thermal Stability Variation during the Cell Cycle. Cell. 2018;173:1495-1507.e18 pubmed publisher
Dai L, Zhao T, Bisteau X, Sun W, Prabhu N, Lim Y, et al. Modulation of Protein-Interaction States through the Cell Cycle. Cell. 2018;173:1481-1494.e13 pubmed publisher
Drpic D, Almeida A, Aguiar P, Renda F, Damas J, Lewin H, et al. Chromosome Segregation Is Biased by Kinetochore Size. Curr Biol. 2018;28:1344-1356.e5 pubmed publisher
Kim M, Cho H, Yoon H, Ahn Y, Park E, Jin Y, et al. JIB-04, A Small Molecule Histone Demethylase Inhibitor, Selectively Targets Colorectal Cancer Stem Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway. Sci Rep. 2018;8:6611 pubmed publisher
Park Y, Ahn J, Cho M, Lee J. ATP depletion during mitotic arrest induces mitotic slippage and APC/CCdh1-dependent cyclin B1 degradation. Exp Mol Med. 2018;50:46 pubmed publisher
Hsu C, Lecland N, Pendaries V, Viodé C, Redoules D, Paul C, et al. Stabilization of microtubules restores barrier function after cytokine-induced defects in reconstructed human epidermis. J Dermatol Sci. 2018;91:87-96 pubmed publisher
E Hermosilla V, Salgado G, Riffo E, Escobar D, Hepp M, Farkas C, et al. SALL2 represses cyclins D1 and E1 expression and restrains G1/S cell cycle transition and cancer-related phenotypes. Mol Oncol. 2018;12:1026-1046 pubmed publisher
Sime W, Niu Q, Abassi Y, Masoumi K, Zarrizi R, Køhler J, et al. BAP1 induces cell death via interaction with 14-3-3 in neuroblastoma. Cell Death Dis. 2018;9:458 pubmed publisher
McMillan E, Ryu M, Diep C, Mendiratta S, Clemenceau J, Vaden R, et al. Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer. Cell. 2018;173:864-878.e29 pubmed publisher
Zhang L, Feng Z, Su M, Jiang X, Chen X, Wang Y, et al. Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells. Eur J Pharmacol. 2018;830:17-25 pubmed publisher
Gu M, Li M, Gao D, Liu L, Lang Y, Yang S, et al. The vanillin derivative 6-bromine-5-hydroxy-4-methoxybenzaldehyde induces aberrant mitotic progression and enhances radio-sensitivity accompanying suppression the expression of PLK1 in esophageal squamous cell carcinoma. Toxicol Appl Pharmacol. 2018;348:76-84 pubmed publisher
Zheng W, Lin Y, Fang W, Zhao X, Lou Y, Wang G, et al. The endosomal recycling of FgSnc1 by FgSnx41-FgSnx4 heterodimer is essential for polarized growth and pathogenicity in Fusarium graminearum. New Phytol. 2018;219:654-671 pubmed publisher
Li M, Gu M, Tian X, Xiao B, Lu S, Zhu W, et al. Hydroxylated-Graphene Quantum Dots Induce DNA Damage and Disrupt Microtubule Structure in Human Esophageal Epithelial Cells. Toxicol Sci. 2018;164:339-352 pubmed publisher
Jiang T, Hoover M, Holt M, Freitas M, Marshall A, Young N. Middle-Down Characterization of the Cell Cycle Dependence of Histone H4 Posttranslational Modifications and Proteoforms. Proteomics. 2018;18:e1700442 pubmed publisher
Deng T, Yan G, Song X, Xie L, Zhou Y, Li J, et al. Deubiquitylation and stabilization of p21 by USP11 is critical for cell-cycle progression and DNA damage responses. Proc Natl Acad Sci U S A. 2018;115:4678-4683 pubmed publisher
Tang Z, Yang J, Wang X, Zeng M, Wang J, Wang A, et al. Active DNA end processing in micronuclei of ovarian cancer cells. BMC Cancer. 2018;18:426 pubmed publisher
Belur Nagaraj A, Kovalenko O, Avelar R, Joseph P, Brown A, Surti A, et al. Mitotic Exit Dysfunction through the Deregulation of APC/C Characterizes Cisplatin-Resistant State in Epithelial Ovarian Cancer. Clin Cancer Res. 2018;24:4588-4601 pubmed publisher
Ghosh L, Jain A, Sundaresan N, Chatterjee K. Elucidating molecular events underlying topography mediated cardiomyogenesis of stem cells on 3D nanofibrous scaffolds. Mater Sci Eng C Mater Biol Appl. 2018;88:104-114 pubmed publisher
Walther N, Hossain M, Politi A, Koch B, Kueblbeck M, Ødegård Fougner Ø, et al. A quantitative map of human Condensins provides new insights into mitotic chromosome architecture. J Cell Biol. 2018;217:2309-2328 pubmed publisher
Wu X, Shen Y. PMN inhibits colorectal cancer cells through inducing mitotic arrest and p53-dependent apoptosis via the inhibition of tubulin polymerization. Biochem Biophys Res Commun. 2018;499:927-933 pubmed publisher
Platani M, Samejima I, Samejima K, Kanemaki M, Earnshaw W. Seh1 targets GATOR2 and Nup153 to mitotic chromosomes. J Cell Sci. 2018;131: pubmed publisher
Saito Sasaki N, Sawada Y, Mashima E, Yamaguchi T, Ohmori S, Yoshioka H, et al. Maresin-1 suppresses imiquimod-induced skin inflammation by regulating IL-23 receptor expression. Sci Rep. 2018;8:5522 pubmed publisher
Okubo Y, Kasamatsu A, Yamatoji M, Fushimi K, Ishigami T, Shimizu T, et al. Diacylglycerol lipase alpha promotes tumorigenesis in oral cancer by cell-cycle progression. Exp Cell Res. 2018;367:112-118 pubmed publisher
Takada N, Naito T, Inoue T, Nakayama K, Takatsu H, Shin H. Phospholipid-flipping activity of P4-ATPase drives membrane curvature. EMBO J. 2018;37: pubmed publisher
Ravindran M, Spriggs C, Verhey K, Tsai B. Dynein Engages and Disassembles Cytosol-Localized Simian Virus 40 To Promote Infection. J Virol. 2018;92: pubmed publisher
Huang C, Fu C, Wren J, Wang X, Zhang F, Zhang Y, et al. Tetraspanin-enriched microdomains regulate digitation junctions. Cell Mol Life Sci. 2018;75:3423-3439 pubmed publisher
Zenker J, White M, Gasnier M, Alvarez Y, Lim H, Bissiere S, et al. Expanding Actin Rings Zipper the Mouse Embryo for Blastocyst Formation. Cell. 2018;173:776-791.e17 pubmed publisher
Ganier O, Schnerch D, Oertle P, Lim R, Plodinec M, Nigg E. Structural centrosome aberrations promote non-cell-autonomous invasiveness. EMBO J. 2018;37: pubmed publisher
Monteonofrio L, Valente D, Ferrara M, Camerini S, Miscione R, Crescenzi M, et al. HIPK2 and extrachromosomal histone H2B are separately recruited by Aurora-B for cytokinesis. Oncogene. 2018;37:3562-3574 pubmed publisher
Chang C, Chen Y, Quintanilla C, Hsieh T, Liou J. EB1 binding restricts STIM1 translocation to ER-PM junctions and regulates store-operated Ca2+ entry. J Cell Biol. 2018;217:2047-2058 pubmed publisher
Gonçalves D, Park D, Schmidt T, Werner C. Modular peptide-functionalized gold nanorods for effective glioblastoma multicellular tumor spheroid targeting. Biomater Sci. 2018;6:1140-1146 pubmed publisher
Sferra A, Fattori F, Rizza T, Flex E, Bellacchio E, Bruselles A, et al. Defective kinesin binding of TUBB2A causes progressive spastic ataxia syndrome resembling sacsinopathy. Hum Mol Genet. 2018;27:1892-1904 pubmed publisher
Martin M, Veloso A, Wu J, Katrukha E, Akhmanova A. Control of endothelial cell polarity and sprouting angiogenesis by non-centrosomal microtubules. elife. 2018;7: pubmed publisher
Saxena N, Mogha P, Dash S, Majumder A, Jadhav S, Sen S. Matrix elasticity regulates mesenchymal stem cell chemotaxis. J Cell Sci. 2018;131: pubmed publisher
Fassier C, Fréal A, Gasmi L, Delphin C, Ten Martin D, De Gois S, et al. Motor axon navigation relies on Fidgetin-like 1-driven microtubule plus end dynamics. J Cell Biol. 2018;217:1719-1738 pubmed publisher
Lin C, Kitagawa M, Tang X, Hou M, Wu J, Qu D, et al. CoA synthase regulates mitotic fidelity via CBP-mediated acetylation. Nat Commun. 2018;9:1039 pubmed publisher
Bryant J, Brown M, Dobrikov M, Dobrikova E, Gemberling S, Zhang Q, et al. Regulation of Hypoxia-Inducible Factor 1α during Hypoxia by DAP5-Induced Translation of PHD2. Mol Cell Biol. 2018;38: pubmed publisher
Martínez Carrera L, Gabriel E, Donohoe C, Holker I, Mariappan A, Storbeck M, et al. Novel insights into SMALED2: BICD2 mutations increase microtubule stability and cause defects in axonal and NMJ development. Hum Mol Genet. 2018;27:1772-1784 pubmed publisher
Zhu Z, Liu J, Li K, Zheng J, Xiong Z. KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells. Oncogene. 2018;37:2936-2952 pubmed publisher
Larsson V, Jafferali M, Vijayaraghavan B, Figueroa R, Hallberg E. Mitotic spindle assembly and ?-tubulin localisation depend on the integral nuclear membrane protein Samp1. J Cell Sci. 2018;131: pubmed publisher
Yi Q, Chen Q, Liang C, Yan H, Zhang Z, Xiang X, et al. HP1 links centromeric heterochromatin to centromere cohesion in mammals. EMBO Rep. 2018;19: pubmed publisher
Takagi M, Ono T, Natsume T, Sakamoto C, Nakao M, Saitoh N, et al. Ki-67 and condensins support the integrity of mitotic chromosomes through distinct mechanisms. J Cell Sci. 2018;131: pubmed publisher
Eichwald C, Ackermann M, Nibert M. The dynamics of both filamentous and globular mammalian reovirus viral factories rely on the microtubule network. Virology. 2018;518:77-86 pubmed publisher
Wangsa D, Quintanilla I, Torabi K, Vila Casadesús M, Ercilla A, Klus G, et al. Near-tetraploid cancer cells show chromosome instability triggered by replication stress and exhibit enhanced invasiveness. FASEB J. 2018;32:3502-3517 pubmed publisher
Wei B, Huang C, Liu B, Wang Y, Xia N, Fan Q, et al. Mitotic Phosphorylation of SENP3 Regulates DeSUMOylation of Chromosome-Associated Proteins and Chromosome Stability. Cancer Res. 2018;78:2171-2178 pubmed publisher
Nakashima M, Watanabe M, Uchimaru K, Horie R. Trogocytosis of ligand-receptor complex and its intracellular transport in CD30 signalling. Biol Cell. 2018;110:109-124 pubmed publisher
Snyder C, Yu L, Ngo T, Sheinson D, Zhu Y, Tseng M, et al. In vitro assessment of chemotherapy-induced neuronal toxicity. Toxicol In Vitro. 2018;50:109-123 pubmed publisher
Lee M, Kim I, Park K, Kim J, Baek S, Kim K. Mitosis-specific phosphorylation of Mis18α by Aurora B kinase enhances kinetochore recruitment of polo-like kinase 1. Oncotarget. 2018;9:1563-1576 pubmed publisher
Guilbert S, Lambert H, Rodrigue M, Fuchs M, Landry J, Lavoie J. HSPB8 and BAG3 cooperate to promote spatial sequestration of ubiquitinated proteins and coordinate the cellular adaptive response to proteasome insufficiency. FASEB J. 2018;32:3518-3535 pubmed publisher
Behnfeldt J, Acharya S, Tangeman L, Gocha A, Keirsey J, Groden J. A tri-serine cluster within the topoisomerase IIα-interaction domain of the BLM helicase is required for regulating chromosome breakage in human cells. Hum Mol Genet. 2018;27:1241-1251 pubmed publisher
McHedlishvili N, Matthews H, Corrigan A, Baum B. Two-step interphase microtubule disassembly aids spindle morphogenesis. BMC Biol. 2018;16:14 pubmed publisher
Murayama Y, Samora C, Kurokawa Y, Iwasaki H, Uhlmann F. Establishment of DNA-DNA Interactions by the Cohesin Ring. Cell. 2018;172:465-477.e15 pubmed publisher
Madero Pérez J, Fdez E, Fernández B, Lara Ordóñez A, Blanca Ramírez M, Gomez Suaga P, et al. Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation. Mol Neurodegener. 2018;13:3 pubmed publisher
Verónica Donoso M, Hernandez F, Villalón T, Acuna Castillo C, Pablo Huidobro Toro J. Pharmacological dissection of the cellular mechanisms associated to the spontaneous and the mechanically stimulated ATP release by mesentery endothelial cells: roles of thrombin and TRPV. Purinergic Signal. 2018;14:121-139 pubmed publisher
Sala K, Raimondi A, Tonoli D, Tacchetti C, de Curtis I. Identification of a membrane-less compartment regulating invadosome function and motility. Sci Rep. 2018;8:1164 pubmed publisher
Yang Y, Zhang X, Ge H, Liu W, Sun E, Ma Y, et al. Epothilone B Benefits Nigrostriatal Pathway Recovery by Promoting Microtubule Stabilization After Intracerebral Hemorrhage. J Am Heart Assoc. 2018;7: pubmed publisher
Orellana A, García González V, Lopez R, Pascual Guiral S, Lozoya E, Diaz J, et al. Application of a phenotypic drug discovery strategy to identify biological and chemical starting points for inhibition of TSLP production in lung epithelial cells. PLoS ONE. 2018;13:e0189247 pubmed publisher
Santos Barriopedro I, Bosch Presegué L, Marazuela Duque A, de la Torre C, Colomer C, Vazquez B, et al. SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway. Nat Commun. 2018;9:101 pubmed publisher
Norkowski S, Körner B, Greune L, Stolle A, Lubos M, Hardwidge P, et al. Bacterial LPX motif-harboring virulence factors constitute a species-spanning family of cell-penetrating effectors. Cell Mol Life Sci. 2018;75:2273-2289 pubmed publisher
Lindman J, Khammy M, Lundegaard P, Aalkjær C, Jepps T. Microtubule Regulation of Kv7 Channels Orchestrates cAMP-Mediated Vasorelaxations in Rat Arterial Smooth Muscle. Hypertension. 2018;71:336-345 pubmed publisher
Vallot A, Leontiou I, Cladière D, El Yakoubi W, Bolte S, Buffin E, et al. Tension-Induced Error Correction and Not Kinetochore Attachment Status Activates the SAC in an Aurora-B/C-Dependent Manner in Oocytes. Curr Biol. 2018;28:130-139.e3 pubmed publisher
Pongrac I, Ahmed L, Mlinarić H, Jurašin D, Pavicic I, Marjanovic Cermak A, et al. Surface coating affects uptake of silver nanoparticles in neural stem cells. J Trace Elem Med Biol. 2018;50:684-692 pubmed publisher
Feitosa W, Hwang K, Morris P. Temporal and SUMO-specific SUMOylation contribute to the dynamics of Polo-like kinase 1 (PLK1) and spindle integrity during mouse oocyte meiosis. Dev Biol. 2018;434:278-291 pubmed publisher
Chan Y, Fugger K, West S. Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations. Nat Cell Biol. 2018;20:92-103 pubmed publisher
Logan C, Bowen C, Menko A. Functional role for stable microtubules in lens fiber cell elongation. Exp Cell Res. 2018;362:477-488 pubmed publisher
Bonaiuti P, Chiroli E, Gross F, Corno A, Vernieri C, Stefl M, et al. Cells Escape an Operational Mitotic Checkpoint through a Stochastic Process. Curr Biol. 2018;28:28-37.e7 pubmed publisher
Makiyama T, Higashi S, Sakane H, Nogami S, Shirataki H. ?-Taxilin temporally regulates centrosome disjunction in a Nek2A-dependent manner. Exp Cell Res. 2018;362:412-423 pubmed publisher
Xiao J, Rijal P, Schimanski L, Tharkeshwar A, Wright E, Annaert W, et al. Characterization of Influenza Virus Pseudotyped with Ebolavirus Glycoprotein. J Virol. 2018;92: pubmed publisher
Deluca K, Meppelink A, Broad A, Mick J, Peersen O, Pektas S, et al. Aurora A kinase phosphorylates Hec1 to regulate metaphase kinetochore-microtubule dynamics. J Cell Biol. 2018;217:163-177 pubmed publisher
Zhang J, Bu X, Wang H, Zhu Y, Geng Y, Nihira N, et al. Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance. Nature. 2018;553:91-95 pubmed publisher
Bloom M, Koshland D, Guacci V. Cohesin Function in Cohesion, Condensation, and DNA Repair Is Regulated by Wpl1p via a Common Mechanism in Saccharomyces cerevisiae. Genetics. 2018;208:111-124 pubmed publisher
Le V, Lee J, Chaterji S, Spencer A, Liu Y, Kim P, et al. Syndecan-1 in mechanosensing of nanotopological cues in engineered materials. Biomaterials. 2018;155:13-24 pubmed publisher
Lewis T, Zareba M, Link B, Besharse J. Cone myoid elongation involves unidirectional microtubule movement mediated by dynein-1. Mol Biol Cell. 2018;29:180-190 pubmed publisher
Liang C, Chen Q, Yi Q, Zhang M, Yan H, Zhang B, et al. A kinase-dependent role for Haspin in antagonizing Wapl and protecting mitotic centromere cohesion. EMBO Rep. 2018;19:43-56 pubmed publisher
Rhys A, Monteiro P, Smith C, Vaghela M, Arnandis T, Kato T, et al. Loss of E-cadherin provides tolerance to centrosome amplification in epithelial cancer cells. J Cell Biol. 2018;217:195-209 pubmed publisher
Hu B, Chen M, Huang R, Huang Y, Xu Y, Yin W, et al. In vivo imaging of Mauthner axon regeneration, remyelination and synapses re-establishment after laser axotomy in zebrafish larvae. Exp Neurol. 2018;300:67-73 pubmed publisher
Huang Y, Li T, Ems McClung S, Walczak C, Prigent C, Zhu X, et al. Aurora A activation in mitosis promoted by BuGZ. J Cell Biol. 2018;217:107-116 pubmed publisher
Bao X, Liu H, Liu X, Ruan K, Zhang Y, Zhang Z, et al. Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation. J Mol Cell Biol. 2018;10:18-32 pubmed publisher
Deftu A, Filippi A, Gheorghe R, Ristoiu V. CXCL1 activates TRPV1 via Gi/o protein and actin filaments. Life Sci. 2018;193:282-291 pubmed publisher
Grey W, Ivey A, Milne T, Haferlach T, Grimwade D, Uhlmann F, et al. The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukaemia cell viability. Biochim Biophys Acta Mol Cell Res. 2018;1865:105-116 pubmed publisher
O Sullivan J, Carroll D, Cao Y, Salicru A, Bochner B. Leveraging Siglec-8 endocytic mechanisms to kill human eosinophils and malignant mast cells. J Allergy Clin Immunol. 2018;141:1774-1785.e7 pubmed publisher
Amanullah A, Mishra R, Upadhyay A, Reddy P, Das R, Mishra A. Indomethacin elicits proteasomal dysfunctions develops apoptosis through mitochondrial abnormalities. J Cell Physiol. 2018;233:1685-1699 pubmed publisher
Meng X, Cui B, Cheng D, Lyu H, Jiang L, Zheng K, et al. Activated proline-rich tyrosine kinase 2 regulates meiotic spindle assembly in the mouse oocyte. J Cell Biochem. 2018;119:736-747 pubmed publisher
Magliocca V, Petrini S, Franchin T, Borghi R, Niceforo A, Abbaszadeh Z, et al. Identifying the dynamics of actin and tubulin polymerization in iPSCs and in iPSC-derived neurons. Oncotarget. 2017;8:111096-111109 pubmed publisher
Fei W, Kijima D, Hashimoto M, Hashimura M, Oguri Y, Kajita S, et al. A functional role of LEFTY during progesterone therapy for endometrial carcinoma. Cell Commun Signal. 2017;15:56 pubmed publisher
Cao J, Ehling M, März S, Seebach J, Tarbashevich K, Sixta T, et al. Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis. Nat Commun. 2017;8:2210 pubmed publisher
Atalay P, Asci O, Kaya F, Tuna B. Hydrogen peroxide prolongs mitotic arrest in a dose dependent manner and independently of the spindle assembly checkpoint activity in Saccharomyces cerevisiae. Acta Biol Hung. 2017;68:477-489 pubmed publisher
Mühe J, Wang F. Species-specific functions of Epstein-Barr virus nuclear antigen 2 (EBNA2) reveal dual roles for initiation and maintenance of B cell immortalization. PLoS Pathog. 2017;13:e1006772 pubmed publisher
Huang Z, Li N, Rao K, Liu C, Huang Y, Ma M, et al. Development of a data-processing method based on Bayesian k-means clustering to discriminate aneugens and clastogens in a high-content micronucleus assay. Hum Exp Toxicol. 2017;:960327117695635 pubmed publisher
Li D, Liu S, Zhu L, Wang Y, Chen Y, Liu J, et al. FBXW8-dependent degradation of MRFAP1 in anaphase controls mitotic cell death. Oncotarget. 2017;8:97178-97186 pubmed publisher
Liao P, Zeng S, Zhou X, Chen T, Zhou F, Cao B, et al. Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding. Mol Cell. 2017;68:1134-1146.e6 pubmed publisher
Taulet N, Vitre B, Anguille C, Douanier A, Rocancourt M, Taschner M, et al. IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning. Nat Commun. 2017;8:1928 pubmed publisher
Tas R, Chazeau A, Cloin B, Lambers M, Hoogenraad C, Kapitein L. Differentiation between Oppositely Oriented Microtubules Controls Polarized Neuronal Transport. Neuron. 2017;96:1264-1271.e5 pubmed publisher
Alves Silva J, Tavares I, Guimarães E, Costa Franco M, Figueiredo B, Marques J, et al. Modulation of Microtubule Dynamics Affects Brucella abortus Intracellular Survival, Pathogen-Containing Vacuole Maturation, and Pro-inflammatory Cytokine Production in Infected Macrophages. Front Microbiol. 2017;8:2217 pubmed publisher
Ito S, Okuda S, Abe M, Fujimoto M, Onuki T, Nishimura T, et al. Induced cortical tension restores functional junctions in adhesion-defective carcinoma cells. Nat Commun. 2017;8:1834 pubmed publisher
Ichikawa K, Tomioka S, Suzuki Y, Nakamura R, Doi K, Yoshimura J, et al. Centromere evolution and CpG methylation during vertebrate speciation. Nat Commun. 2017;8:1833 pubmed publisher
Messaoudi K, Ali A, Ishaq R, Palazzo A, Sliwa D, Bluteau O, et al. Critical role of the HDAC6-cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect. Nat Commun. 2017;8:1786 pubmed publisher
Sun J, Liu Y, Ge M, Zhou G, Sun W, Liu D, et al. A Distinct Endocytic Mechanism of Functionalized-Silica Nanoparticles in Breast Cancer Stem Cells. Sci Rep. 2017;7:16236 pubmed publisher
Mimura Y, Takemoto S, Tachibana T, Ogawa Y, Nishimura M, Yokota H, et al. A statistical image analysis framework for pore-free islands derived from heterogeneity distribution of nuclear pore complexes. Sci Rep. 2017;7:16315 pubmed publisher
Smith L, Farzan R, Ali S, Buluwela L, Saurin A, Meek D. The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation. Sci Rep. 2017;7:16115 pubmed publisher
Berenjeno I, Piñeiro R, Castillo S, Pearce W, McGranahan N, Dewhurst S, et al. Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling. Nat Commun. 2017;8:1773 pubmed publisher
Li F, Sawada J, Komatsu M. R-Ras-Akt axis induces endothelial lumenogenesis and regulates the patency of regenerating vasculature. Nat Commun. 2017;8:1720 pubmed publisher
Bouguenina H, Salaün D, Mangon A, Muller L, Baudelet E, Camoin L, et al. EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions. Proc Natl Acad Sci U S A. 2017;114:E10687-E10696 pubmed publisher
Stojkov D, Amini P, Oberson K, Sokollik C, Duppenthaler A, Simon H, et al. ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formation. J Cell Biol. 2017;216:4073-4090 pubmed publisher
Thillaiappan N, Chavda A, Tovey S, Prole D, Taylor C. Ca2+ signals initiate at immobile IP3 receptors adjacent to ER-plasma membrane junctions. Nat Commun. 2017;8:1505 pubmed publisher
Ma X, Wang L, Huang D, Li Y, Yang D, Li T, et al. Polo-like kinase 1 coordinates biosynthesis during cell cycle progression by directly activating pentose phosphate pathway. Nat Commun. 2017;8:1506 pubmed publisher
Durak G, Brownlee C, Wheeler G. The role of the cytoskeleton in biomineralisation in haptophyte algae. Sci Rep. 2017;7:15409 pubmed publisher
Hu B, Leow W, Cai P, Li Y, Wu Y, Chen X. Nanomechanical Force Mapping of Restricted Cell-To-Cell Collisions Oscillating between Contraction and Relaxation. ACS Nano. 2017;: pubmed publisher
Baarlink C, Plessner M, Sherrard A, Morita K, Misu S, Virant D, et al. A transient pool of nuclear F-actin at mitotic exit controls chromatin organization. Nat Cell Biol. 2017;19:1389-1399 pubmed publisher
Qian J, Garcia Gimeno M, Beullens M, Manzione M, Van der Hoeven G, Igual J, et al. An Attachment-Independent Biochemical Timer of the Spindle Assembly Checkpoint. Mol Cell. 2017;68:715-730.e5 pubmed publisher
Sekine E, Schmidt N, Gaboriau D, O Hare P. Spatiotemporal dynamics of HSV genome nuclear entry and compaction state transitions using bioorthogonal chemistry and super-resolution microscopy. PLoS Pathog. 2017;13:e1006721 pubmed publisher
She T, Feng J, Lian S, Li R, Zhao C, Song G, et al. Sarsaparilla (Smilax Glabra Rhizome) Extract Activates Redox-Dependent ATM/ATR Pathway to Inhibit Cancer Cell Growth by S Phase Arrest, Apoptosis, and Autophagy. Nutr Cancer. 2017;:1-9 pubmed publisher
Reitsma J, Liu X, Reichermeier K, Moradian A, Sweredoski M, Hess S, et al. Composition and Regulation of the Cellular Repertoire of SCF Ubiquitin Ligases. Cell. 2017;171:1326-1339.e14 pubmed publisher
Lee M, Rivera Rivera Y, Moreno C, Saavedra H. The E2F activators control multiple mitotic regulators and maintain genomic integrity through Sgo1 and BubR1. Oncotarget. 2017;8:77649-77672 pubmed publisher
Chen Y, Zhang K, Wang X, Li Q, Wu Q, Ning X. Cell cycle-dependent translocation and regulatory mechanism of CacyBP/SIP in gastric cancer cells. Anticancer Drugs. 2017;: pubmed publisher
Stevenson N, Bergen D, Skinner R, Kague E, Martin Silverstone E, Robson Brown K, et al. Giantin-knockout models reveal a feedback loop between Golgi function and glycosyltransferase expression. J Cell Sci. 2017;130:4132-4143 pubmed publisher
Huang M, Ma X, Shi H, Hu L, Fan Z, Pang L, et al. FAM83D, a microtubule-associated protein, promotes tumor growth and progression of human gastric cancer. Oncotarget. 2017;8:74479-74493 pubmed publisher
Gendarme M, Baumann J, Ignashkova T, Lindemann R, Reiling J. Image-based drug screen identifies HDAC inhibitors as novel Golgi disruptors synergizing with JQ1. Mol Biol Cell. 2017;28:3756-3772 pubmed publisher
Zimmer A, Tendler A, Katzir I, Mayo A, Alon U. Prediction of drug cocktail effects when the number of measurements is limited. PLoS Biol. 2017;15:e2002518 pubmed publisher
Zhang W, Yeung C, Wu L, Yuen K. E3 ubiquitin ligase Bre1 couples sister chromatid cohesion establishment to DNA replication in Saccharomyces cerevisiae. elife. 2017;6: pubmed publisher
Graessl M, Koch J, Calderon A, Kamps D, Banerjee S, Mazel T, et al. An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns. J Cell Biol. 2017;216:4271-4285 pubmed publisher
Kasai S, Richardson M, Torii S, Yasumoto K, Shima H, Igarashi K, et al. Increase in proapoptotic activity of inhibitory PAS domain protein via phosphorylation by MK2. FEBS J. 2017;284:4115-4127 pubmed publisher
Kittur H, Tay A, Hua A, Yu M, Di Carlo D. Probing Cell Adhesion Profiles with a Microscale Adhesive Choice Assay. Biophys J. 2017;113:1858-1867 pubmed publisher
Mijic S, Zellweger R, Chappidi N, Berti M, Jacobs K, Mutreja K, et al. Replication fork reversal triggers fork degradation in BRCA2-defective cells. Nat Commun. 2017;8:859 pubmed publisher
Liu Z, Cao K, Xiao Z, Qiao L, Wang X, Shang B, et al. VRK1 promotes cisplatin resistance by up-regulating c-MYC via c-Jun activation and serves as a therapeutic target in esophageal squamous cell carcinoma. Oncotarget. 2017;8:65642-65658 pubmed publisher
Chen D, Li X, Liu X, Liu X, Jiang X, Du J, et al. NQO2 inhibition relieves reactive oxygen species effects on mouse oocyte meiotic maturation and embryo development. Biol Reprod. 2017;97:598-611 pubmed publisher
Dehart D, Lemasters J, Maldonado E. Erastin-Like Anti-Warburg Agents Prevent Mitochondrial Depolarization Induced by Free Tubulin and Decrease Lactate Formation in Cancer Cells. SLAS Discov. 2017;:2472555217731556 pubmed publisher
Gulluni F, Martini M, De Santis M, Campa C, Ghigo A, Margaria J, et al. Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2? Scaffolding Function. Cancer Cell. 2017;32:444-459.e7 pubmed publisher
Zhu R, Antoku S, Gundersen G. Centrifugal Displacement of Nuclei Reveals Multiple LINC Complex Mechanisms for Homeostatic Nuclear Positioning. Curr Biol. 2017;27:3097-3110.e5 pubmed publisher
Di Maio N, Vicidomini R, Angrisani A, Belli V, Furia M, Turano M. A new role for human dyskerin in vesicular trafficking. FEBS Open Bio. 2017;7:1453-1468 pubmed publisher
Lane S, Jones K. Chromosome biorientation and APC activity remain uncoupled in oocytes with reduced volume. J Cell Biol. 2017;216:3949-3957 pubmed publisher
Barros Becker F, Lam P, Fisher R, Huttenlocher A. Live imaging reveals distinct modes of neutrophil and macrophage migration within interstitial tissues. J Cell Sci. 2017;130:3801-3808 pubmed publisher
van der Vaart B, Fischböck J, Mieck C, Pichler P, Mechtler K, Medema R, et al. TORC1 signaling exerts spatial control over microtubule dynamics by promoting nuclear export of Stu2. J Cell Biol. 2017;216:3471-3484 pubmed publisher
Garanina A, Kisurina Evgenieva O, Erokhina M, Smirnova E, Factor V, Onishchenko G. Consecutive entosis stages in human substrate-dependent cultured cells. Sci Rep. 2017;7:12555 pubmed publisher
Dan Wei -, Gao N, Li L, Zhu J, Diao L, Huang J, et al. ?-Tubulin Acetylation Restricts Axon Overbranching by Dampening Microtubule Plus-End Dynamics in Neurons. Cereb Cortex. 2017;:1-15 pubmed publisher
Landino J, Norris S, Li M, Ballister E, Lampson M, Ohi R. Two mechanisms coordinate the recruitment of the chromosomal passenger complex to the plane of cell division. Mol Biol Cell. 2017;28:3634-3646 pubmed publisher
John R, Atri Y, Chand V, Jaiswal N, Raj K, Nag A. Cell cycle-dependent regulation of cytoglobin by Skp2. FEBS Lett. 2017;591:3507-3522 pubmed publisher
Hozumi S, Aoki S, Kikuchi Y. Nuclear movement regulated by non-Smad Nodal signaling via JNK is associated with Smad signaling during zebrafish endoderm specification. Development. 2017;144:4015-4025 pubmed publisher
Overlack K, Bange T, Weissmann F, Faesen A, Maffini S, Primorac I, et al. BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling. Curr Biol. 2017;27:2915-2927.e7 pubmed publisher
Ifuji A, Kuga T, Kaibori Y, Saito Y, Nakayama Y. A novel immunofluorescence method to visualize microtubules in the antiparallel overlaps of microtubule-plus ends in the anaphase and telophase midzone. Exp Cell Res. 2017;360:347-357 pubmed publisher
Vanover D, Smith D, Blanchard E, Alonas E, Kirschman J, Lifland A, et al. RSV glycoprotein and genomic RNA dynamics reveal filament assembly prior to the plasma membrane. Nat Commun. 2017;8:667 pubmed publisher
Bertoletti F, Cea V, Liang C, Lanati T, Maffia A, Avarello M, et al. Phosphorylation regulates human pol? stability and damage bypass throughout the cell cycle. Nucleic Acids Res. 2017;45:9441-9454 pubmed publisher
Sanders A, Chang K, Zhu X, Thoppil R, Holmes W, Kaverina I. Nonrandom γ-TuNA-dependent spatial pattern of microtubule nucleation at the Golgi. Mol Biol Cell. 2017;28:3181-3192 pubmed publisher
Beaudet D, Akhshi T, Phillipp J, Law C, Piekny A. Active Ran regulates anillin function during cytokinesis. Mol Biol Cell. 2017;28:3517-3531 pubmed publisher
Zhang X, Chen X, Liu J, Xu X, Zhang Y, Ruan Z, et al. Palladin is a novel microtubule-associated protein responsible for spindle orientation. Sci Rep. 2017;7:11806 pubmed publisher
Torriano S, Erkilic N, Faugère V, Damodar K, Hamel C, Roux A, et al. Pathogenicity of a novel missense variant associated with choroideremia and its impact on gene replacement therapy. Hum Mol Genet. 2017;26:3573-3584 pubmed publisher
Mukherjee R, Majumder P, Chakrabarti O. MGRN1-mediated ubiquitination of α-tubulin regulates microtubule dynamics and intracellular transport. Traffic. 2017;18:791-807 pubmed publisher
Ducasse R, Wang W, Navarro M, Debons N, Colin A, Gautier J, et al. Programmed Self-Assembly of a Biochemical and Magnetic Scaffold to Trigger and Manipulate Microtubule Structures. Sci Rep. 2017;7:11344 pubmed publisher
Mehrnezhad A, Park K. Multifrequency Optomechanical Stiffness Measurement of Single Adherent Cells on a Solid Substrate with High Throughput. Anal Chem. 2017;89:10841-10849 pubmed publisher
Burman J, Pickles S, Wang C, Sekine S, Vargas J, Zhang Z, et al. Mitochondrial fission facilitates the selective mitophagy of protein aggregates. J Cell Biol. 2017;216:3231-3247 pubmed publisher
Vujanovic M, Krietsch J, Raso M, Terraneo N, Zellweger R, Schmid J, et al. Replication Fork Slowing and Reversal upon DNA Damage Require PCNA Polyubiquitination and ZRANB3 DNA Translocase Activity. Mol Cell. 2017;67:882-890.e5 pubmed publisher
Escobar Aguirre M, Zhang H, Jamieson Lucy A, Mullins M. Microtubule-actin crosslinking factor 1 (Macf1) domain function in Balbiani body dissociation and nuclear positioning. PLoS Genet. 2017;13:e1006983 pubmed publisher
Kourtidis A, Necela B, Lin W, Lu R, Feathers R, Asmann Y, et al. Cadherin complexes recruit mRNAs and RISC to regulate epithelial cell signaling. J Cell Biol. 2017;216:3073-3085 pubmed publisher
Zhong Y, Yang J, Xu W, Wang Y, Zheng C, Li B, et al. KCTD12 promotes tumorigenesis by facilitating CDC25B/CDK1/Aurora A-dependent G2/M transition. Oncogene. 2017;36:6177-6189 pubmed publisher
Alexander K, Rizkallah R. Aurora A Phosphorylation of YY1 during Mitosis Inactivates its DNA Binding Activity. Sci Rep. 2017;7:10084 pubmed publisher
Jinesh G, Kamat A. The Blebbishield Emergency Program Overrides Chromosomal Instability and Phagocytosis Checkpoints in Cancer Stem Cells. Cancer Res. 2017;77:6144-6156 pubmed publisher
Strobel T, Madlener S, Tuna S, Vose S, Lagerweij T, Wurdinger T, et al. Ape1 guides DNA repair pathway choice that is associated with drug tolerance in glioblastoma. Sci Rep. 2017;7:9674 pubmed publisher
Feng S, Sekine S, Pessino V, Li H, Leonetti M, Huang B. Improved split fluorescent proteins for endogenous protein labeling. Nat Commun. 2017;8:370 pubmed publisher
Zitouni S, Mechali F, Papin C, Choquet A, Roche D, Baldin V, et al. The stability of Fbw7α in M-phase requires its phosphorylation by PKC. PLoS ONE. 2017;12:e0183500 pubmed publisher
Alomer R, da Silva E, Chen J, Piekarz K, McDonald K, Sansam C, et al. Esco1 and Esco2 regulate distinct cohesin functions during cell cycle progression. Proc Natl Acad Sci U S A. 2017;114:9906-9911 pubmed publisher
Chen W, Wang W, Tsai T, Li H, Lee Y. DDX3 localizes to the centrosome and prevents multipolar mitosis by epigenetically and translationally modulating p53 expression. Sci Rep. 2017;7:9411 pubmed publisher
Tomoshige S, Kobayashi Y, Hosoba K, Hamamoto A, Miyamoto T, Saito Y. Cytoskeleton-related regulation of primary cilia shortening mediated by melanin-concentrating hormone receptor 1. Gen Comp Endocrinol. 2017;253:44-52 pubmed publisher
Netter P, Anft M, Watzl C. Termination of the Activating NK Cell Immunological Synapse Is an Active and Regulated Process. J Immunol. 2017;199:2528-2535 pubmed publisher
Kee A, Bryce N, Yang L, Polishchuk E, Schevzov G, Weigert R, et al. ER/Golgi trafficking is facilitated by unbranched actin filaments containing Tpm4.2. Cytoskeleton (Hoboken). 2017;74:379-389 pubmed publisher
Bernadzki K, Gawor M, Pęziński M, Mazurek P, Niewiadomski P, Redowicz M, et al. Liprin-α-1 is a novel component of the murine neuromuscular junction and is involved in the organization of the postsynaptic machinery. Sci Rep. 2017;7:9116 pubmed publisher
Bodeen W, Marada S, Truong A, Ogden S. A fixation method to preserve cultured cell cytonemes facilitates mechanistic interrogation of morphogen transport. Development. 2017;144:3612-3624 pubmed publisher
Ikeda M, Tanaka K. Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis. Sci Rep. 2017;7:8794 pubmed publisher
Hanna S, McCoy Simandle K, Miskolci V, Guo P, Cammer M, Hodgson L, et al. The Role of Rho-GTPases and actin polymerization during Macrophage Tunneling Nanotube Biogenesis. Sci Rep. 2017;7:8547 pubmed publisher
Boubakar L, Falk J, Ducuing H, Thoinet K, Reynaud F, Derrington E, et al. Molecular Memory of Morphologies by Septins during Neuron Generation Allows Early Polarity Inheritance. Neuron. 2017;95:834-851.e5 pubmed publisher
Yang C, Wu J, de Heus C, Grigoriev I, Liv N, Yao Y, et al. EB1 and EB3 regulate microtubule minus end organization and Golgi morphology. J Cell Biol. 2017;216:3179-3198 pubmed publisher
Kodama M, Kodama T, Newberg J, Katayama H, Kobayashi M, Hanash S, et al. In vivo loss-of-function screens identify KPNB1 as a new druggable oncogene in epithelial ovarian cancer. Proc Natl Acad Sci U S A. 2017;114:E7301-E7310 pubmed publisher
Becher A, Eiseler T, Porzner M, Walther P, Keil R, Bobrovich S, et al. The armadillo protein p0071 controls KIF3 motor transport. J Cell Sci. 2017;130:3374-3387 pubmed publisher
Hada M, Kim J, Inoue E, Fukuda Y, Tanaka H, Watanabe Y, et al. TH2A is phosphorylated at meiotic centromere by Haspin. Chromosoma. 2017;126:769-780 pubmed publisher
Stauffer S, Zeng Y, Zhou J, Chen X, Chen Y, Dong J. CDK1-mediated mitotic phosphorylation of PBK is involved in cytokinesis and inhibits its oncogenic activity. Cell Signal. 2017;39:74-83 pubmed publisher
Budida R, Stankov M, Döhner K, Buch A, Panayotova Dimitrova D, Tappe K, et al. Herpes simplex virus 1 interferes with autophagy of murine dendritic cells and impairs their ability to stimulate CD8+ T lymphocytes. Eur J Immunol. 2017;47:1819-1834 pubmed publisher
Iwata Y, Klaren W, Lebakken C, Grimm F, Rusyn I. High-Content Assay Multiplexing for Vascular Toxicity Screening in Induced Pluripotent Stem Cell-Derived Endothelial Cells and Human Umbilical Vein Endothelial Cells. Assay Drug Dev Technol. 2017;15:267-279 pubmed publisher
Mackenzie K, Carroll P, Martin C, Murina O, Fluteau A, Simpson D, et al. cGAS surveillance of micronuclei links genome instability to innate immunity. Nature. 2017;548:461-465 pubmed publisher
Takaki T, Montagner M, Serres M, Le Berre M, Russell M, Collinson L, et al. Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability. Nat Commun. 2017;8:16013 pubmed publisher
Shi L, Muthusamy N, Smith D, Bergson C. Dynein binds and stimulates axonal motility of the endosome adaptor and NEEP21 family member, calcyon. Int J Biochem Cell Biol. 2017;90:93-102 pubmed publisher
Lazar Stefanita L, Scolari V, Mercy G, Muller H, Guérin T, Thierry A, et al. Cohesins and condensins orchestrate the 4D dynamics of yeast chromosomes during the cell cycle. EMBO J. 2017;36:2684-2697 pubmed publisher
Wei J, Xu H, Meng W. Noncentrosomal microtubules regulate autophagosome transport through CAMSAP2-EB1 cross-talk. FEBS Lett. 2017;591:2379-2393 pubmed publisher
Ayloo S, Guedes Dias P, Ghiretti A, Holzbaur E. Dynein efficiently navigates the dendritic cytoskeleton to drive the retrograde trafficking of BDNF/TrkB signaling endosomes. Mol Biol Cell. 2017;28:2543-2554 pubmed publisher
Sampson J, O Regan L, Dyer M, Bayliss R, Fry A. Hsp72 and Nek6 Cooperate to Cluster Amplified Centrosomes in Cancer Cells. Cancer Res. 2017;77:4785-4796 pubmed publisher
Niida H, Matsunuma R, Horiguchi R, Uchida C, Nakazawa Y, Motegi A, et al. Phosphorylated HBO1 at UV irradiated sites is essential for nucleotide excision repair. Nat Commun. 2017;8:16102 pubmed publisher
Kagami Y, Ono M, Yoshida K. Plk1 phosphorylation of CAP-H2 triggers chromosome condensation by condensin II at the early phase of mitosis. Sci Rep. 2017;7:5583 pubmed publisher
Di Primio C, Quercioli V, Siano G, Rovere M, Kovacech B, Novak M, et al. The Distance between N and C Termini of Tau and of FTDP-17 Mutants Is Modulated by Microtubule Interactions in Living Cells. Front Mol Neurosci. 2017;10:210 pubmed publisher
Beaujois R, Ottoni E, Zhang X, Gagnon C, Hassine S, Mollet S, et al. The M-phase specific hyperphosphorylation of Staufen2 involved the cyclin-dependent kinase CDK1. BMC Cell Biol. 2017;18:25 pubmed publisher
Seifert J, Rheinlaender J, Lang F, Gawaz M, Schäffer T. Thrombin-induced cytoskeleton dynamics in spread human platelets observed with fast scanning ion conductance microscopy. Sci Rep. 2017;7:4810 pubmed publisher
Nikolic J, Le Bars R, Lama Z, Scrima N, Lagaudrière Gesbert C, Gaudin Y, et al. Negri bodies are viral factories with properties of liquid organelles. Nat Commun. 2017;8:58 pubmed publisher
Jang W, Kim T, Koo J, Kim S, Lim D. Mechanical cue-induced YAP instructs Skp2-dependent cell cycle exit and oncogenic signaling. EMBO J. 2017;36:2510-2528 pubmed publisher
Schecher S, Walter B, Falkenstein M, Macher Goeppinger S, Stenzel P, Krümpelmann K, et al. Cyclin K dependent regulation of Aurora B affects apoptosis and proliferation by induction of mitotic catastrophe in prostate cancer. Int J Cancer. 2017;141:1643-1653 pubmed publisher
Juanes M, Bouguenina H, Eskin J, Jaiswal R, Badache A, Goode B. Adenomatous polyposis coli nucleates actin assembly to drive cell migration and microtubule-induced focal adhesion turnover. J Cell Biol. 2017;216:2859-2875 pubmed publisher
Alonso Lecue P, de Pedro I, Coulon V, Molinuevo R, Lorz C, Segrelles C, et al. Inefficient differentiation response to cell cycle stress leads to genomic instability and malignant progression of squamous carcinoma cells. Cell Death Dis. 2017;8:e2901 pubmed publisher
Quartuccio S, Dipali S, Schindler K. Haspin inhibition reveals functional differences of interchromatid axis-localized AURKB and AURKC. Mol Biol Cell. 2017;28:2233-2240 pubmed publisher
Wei R, Li B, Guo J, Li M, Zhu R, Yang X, et al. Smurf1 targets Securin for ubiquitin-dependent degradation and regulates the metaphase-to-anaphase transition. Cell Signal. 2017;38:60-66 pubmed publisher
Li X, Thome S, Ma X, Amrute Nayak M, Finigan A, Kitt L, et al. MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism. Nat Commun. 2017;8:15986 pubmed publisher
Park J, Holmes W, Lee S, Kim H, Kim D, Kwak M, et al. Mechanochemical feedback underlies coexistence of qualitatively distinct cell polarity patterns within diverse cell populations. Proc Natl Acad Sci U S A. 2017;114:E5750-E5759 pubmed publisher
Dogan T, Gnad F, Chan J, Phu L, Young A, Chen M, et al. Role of the E3 ubiquitin ligase RNF157 as a novel downstream effector linking PI3K and MAPK signaling pathways to the cell cycle. J Biol Chem. 2017;292:14311-14324 pubmed publisher
Booy E, McRae E, Koul A, Lin F, McKenna S. The long non-coding RNA BC200 (BCYRN1) is critical for cancer cell survival and proliferation. Mol Cancer. 2017;16:109 pubmed publisher
Karnowski K, Ajduk A, Wieloch B, Tamborski S, Krawiec K, Wojtkowski M, et al. Optical coherence microscopy as a novel, non-invasive method for the 4D live imaging of early mammalian embryos. Sci Rep. 2017;7:4165 pubmed publisher
Dütting S, Gaits Iacovoni F, Stegner D, Popp M, Antkowiak A, van Eeuwijk J, et al. A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis. Nat Commun. 2017;8:15838 pubmed publisher
Fang X, Hu T, Yin H, Yang J, Tang W, Hu S, et al. Differences in telomerase activity and the effects of AZT in aneuploid and euploid cells in colon cancer. Int J Oncol. 2017;51:525-532 pubmed publisher
Youm I, West M, Li W, Du X, EWERT D, Kopke R. siRNA-loaded biodegradable nanocarriers for therapeutic MAPK1 silencing against cisplatin-induced ototoxicity. Int J Pharm. 2017;528:611-623 pubmed publisher
Glück S, Buttafuoco A, Meier A, Arnoldi F, Vogt B, Schraner E, et al. Rotavirus replication is correlated with S/G2 interphase arrest of the host cell cycle. PLoS ONE. 2017;12:e0179607 pubmed publisher
Aoyama M, Yoshioka Y, Arai Y, Hirai H, Ishimoto R, Nagano K, et al. Intracellular trafficking of particles inside endosomal vesicles is regulated by particle size. J Control Release. 2017;260:183-193 pubmed publisher
Shi Y, Shi Z, Li S, Zhang Y, He B, Peng D, et al. The interactions of single-wall carbon nanohorns with polar epithelium. Int J Nanomedicine. 2017;12:4177-4194 pubmed publisher
Karki M, Keyhaninejad N, Shuster C. Precocious centriole disengagement and centrosome fragmentation induced by mitotic delay. Nat Commun. 2017;8:15803 pubmed publisher
Sridharan H, Ragan K, Guo H, Gilley R, Landsteiner V, Kaiser W, et al. Murine cytomegalovirus IE3-dependent transcription is required for DAI/ZBP1-mediated necroptosis. EMBO Rep. 2017;18:1429-1441 pubmed publisher
Szikora S, Földi I, Tóth K, Migh E, Vig A, Bugyi B, et al. The formin DAAM is required for coordination of the actin and microtubule cytoskeleton in axonal growth cones. J Cell Sci. 2017;130:2506-2519 pubmed publisher
Zhang G, Kruse T, López Méndez B, Sylvestersen K, Garvanska D, Schopper S, et al. Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling. Nat Commun. 2017;8:15822 pubmed publisher
Chen D, Ito S, Hyodo T, Asano Inami E, Yuan H, Senga T. Phosphorylation of DEPDC1 at Ser110 is required to maintain centrosome organization during mitosis. Exp Cell Res. 2017;358:101-110 pubmed publisher
Zhang K, Foster H, Rondelet A, Lacey S, Bahi Buisson N, Bird A, et al. Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated. Cell. 2017;169:1303-1314.e18 pubmed publisher
Ramkumar A, Murthy D, Raja D, Singh A, Krishnan A, Khanna S, et al. Classical autophagy proteins LC3B and ATG4B facilitate melanosome movement on cytoskeletal tracks. Autophagy. 2017;13:1331-1347 pubmed publisher
Park J, Park Y, Ryu I, Choi M, Lee H, Oh N, et al. Misfolded polypeptides are selectively recognized and transported toward aggresomes by a CED complex. Nat Commun. 2017;8:15730 pubmed publisher
Eguchi K, Taoufiq Z, Thorn Seshold O, Trauner D, Hasegawa M, Takahashi T. Wild-Type Monomeric ?-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held. J Neurosci. 2017;37:6043-6052 pubmed publisher
Bai Z, Gao M, Zhang H, Guan Q, Xu J, Li Y, et al. BZML, a novel colchicine binding site inhibitor, overcomes multidrug resistance in A549/Taxol cells by inhibiting P-gp function and inducing mitotic catastrophe. Cancer Lett. 2017;402:81-92 pubmed publisher
Gonçalves D, Rodriguez R, Kurth T, Bray L, Binner M, Jungnickel C, et al. Enhanced targeting of invasive glioblastoma cells by peptide-functionalized gold nanorods in hydrogel-based 3D cultures. Acta Biomater. 2017;58:12-25 pubmed publisher
Zheng L, Li C, Zhen S, Li Y, Huang C. A dynamic cell entry pathway of respiratory syncytial virus revealed by tracking the quantum dot-labeled single virus. Nanoscale. 2017;9:7880-7887 pubmed publisher
Hengeveld R, Vromans M, Vleugel M, Hadders M, Lens S. Inner centromere localization of the CPC maintains centromere cohesion and allows mitotic checkpoint silencing. Nat Commun. 2017;8:15542 pubmed publisher
Iwata T, Uchino T, Koyama A, Johmura Y, Koyama K, Saito T, et al. The G2 checkpoint inhibitor CBP-93872 increases the sensitivity of colorectal and pancreatic cancer cells to chemotherapy. PLoS ONE. 2017;12:e0178221 pubmed publisher
Grassetti A, Hards R, Gerber S. Offline pentafluorophenyl (PFP)-RP prefractionation as an alternative to high-pH RP for comprehensive LC-MS/MS proteomics and phosphoproteomics. Anal Bioanal Chem. 2017;409:4615-4625 pubmed publisher
VALM A, Cohen S, Legant W, Melunis J, Hershberg U, Wait E, et al. Applying systems-level spectral imaging and analysis to reveal the organelle interactome. Nature. 2017;546:162-167 pubmed publisher
Sato Y, Murakami Y, Takahashi M. Semi-retentive cytoskeletal fractionation (SERCYF): A novel method for the biochemical analysis of the organization of microtubule and actin cytoskeleton networks. Biochem Biophys Res Commun. 2017;488:614-620 pubmed publisher
Ferreli C, Lai C, August S, Buggy Y, Kumar P, Brownlow N, et al. STAT4 expression and activation is increased during mitosis in vitro and in vivo in skin- and mucosa-derived cell types: implications in neoplastic and inflammatory skin diseases. J Eur Acad Dermatol Venereol. 2017;31:1663-1673 pubmed publisher
Radhakrishnan A, Jokhun D, Venkatachalapathy S, Shivashankar G. Nuclear Positioning and Its Translational Dynamics Are Regulated by Cell Geometry. Biophys J. 2017;112:1920-1928 pubmed publisher
Hui K, Upadhyaya A. Dynamic microtubules regulate cellular contractility during T-cell activation. Proc Natl Acad Sci U S A. 2017;114:E4175-E4183 pubmed publisher
Robinson C, Evans R, Briggs D, Ramalho J, Hume A. Inefficient recruitment of kinesin-1 to melanosomes precludes it from facilitating their transport. J Cell Sci. 2017;130:2056-2065 pubmed publisher
Jing R, Xi J, Leng Y, Chen W, Wang G, Jia W, et al. Motifs in the amino-terminus of CENP-A are required for its accumulation within the nucleus and at the centromere. Oncotarget. 2017;8:40654-40667 pubmed publisher
Wen L, Zheng Z, Liu A, Lv C, Zhang L, Ao J, et al. Tracking single baculovirus retrograde transportation in host cell via quantum dot-labeling of virus internal component. J Nanobiotechnology. 2017;15:37 pubmed publisher
Jeon H, Cui X, Guo J, Lee J, Kim J, Oh J. TCTP regulates spindle assembly during postovulatory aging and prevents deterioration in mouse oocyte quality. Biochim Biophys Acta Mol Cell Res. 2017;1864:1328-1334 pubmed publisher
Magescas J, Sengmanivong L, Viau A, Mayeux A, Dang T, Burtin M, et al. Spindle pole cohesion requires glycosylation-mediated localization of NuMA. Sci Rep. 2017;7:1474 pubmed publisher
Chen L, Pan J. Dual cyclin-dependent kinase 4/6 inhibition by PD-0332991 induces apoptosis and senescence in oesophageal squamous cell carcinoma cells. Br J Pharmacol. 2017;174:2427-2443 pubmed publisher
Roux A, Loranger A, Lavoie J, Marceau N. Keratin 8/18 regulation of insulin receptor signaling and trafficking in hepatocytes through a concerted phosphoinositide-dependent Akt and Rab5 modulation. FASEB J. 2017;31:3555-3573 pubmed publisher
Xiao B, Deng X, Lim G, Zhou W, Saw W, Zhou Z, et al. p62-Mediated mitochondrial clustering attenuates apoptosis induced by mitochondrial depolarization. Biochim Biophys Acta Mol Cell Res. 2017;1864:1308-1317 pubmed publisher
Leduc C, Etienne Manneville S. Regulation of microtubule-associated motors drives intermediate filament network polarization. J Cell Biol. 2017;216:1689-1703 pubmed publisher
Gorur A, Yuan L, Kenny S, Baba S, Xu K, Schekman R. COPII-coated membranes function as transport carriers of intracellular procollagen I. J Cell Biol. 2017;216:1745-1759 pubmed publisher
Singh V, Connelly Z, Shen X, De Benedetti A. Identification of the proteome complement of humanTLK1 reveals it binds and phosphorylates NEK1 regulating its activity. Cell Cycle. 2017;16:915-926 pubmed publisher
Verdeny Vilanova I, Wehnekamp F, Mohan N, Sandoval Álvarez Ã, Borbely J, Otterstrom J, et al. 3D motion of vesicles along microtubules helps them to circumvent obstacles in cells. J Cell Sci. 2017;130:1904-1916 pubmed publisher
Chang C, Bijian K, Qiu D, Su J, Saad A, Dahabieh M, et al. Endosomal sorting and c-Cbl targeting of paxillin to autophagosomes regulate cell-matrix adhesion turnover in human breast cancer cells. Oncotarget. 2017;8:31199-31214 pubmed publisher
Sheshachalam A, Baier A, Eitzen G. The effect of Rho drugs on mast cell activation and degranulation. J Leukoc Biol. 2017;102:71-81 pubmed publisher
Li C, Zhang P, Jiang A, Mao J, Wei G. A short synthetic peptide fragment of human C2ORF40 has therapeutic potential in breast cancer. Oncotarget. 2017;8:41963-41974 pubmed publisher
Lee S, Rodriguez Bravo V, Kim H, Datta S, Foley E. The PP2AB56 phosphatase promotes the association of Cdc20 with APC/C in mitosis. J Cell Sci. 2017;130:1760-1771 pubmed publisher
Nelson E, Dyall J, Hoenen T, Barnes A, Zhou H, Liang J, et al. The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection. PLoS Negl Trop Dis. 2017;11:e0005540 pubmed publisher
Wortzel I, Koifman G, Rotter V, Seger R, Porat Z. High Throughput Analysis of Golgi Structure by Imaging Flow Cytometry. Sci Rep. 2017;7:788 pubmed publisher
Huhn S, Liu J, Ye C, Lu H, Jiang X, Feng X, et al. Regulation of spindle integrity and mitotic fidelity by BCCIP. Oncogene. 2017;36:4750-4766 pubmed publisher
Plaud C, Joshi V, Marinello M, Pastre D, Galli T, Curmi P, et al. Spastin regulates VAMP7-containing vesicles trafficking in cortical neurons. Biochim Biophys Acta Mol Basis Dis. 2017;1863:1666-1677 pubmed publisher
Jiao X, Huang C, Wu D, Zhang J, Long Y, Chen F, et al. Abce1 orchestrates M-phase entry and cytoskeleton architecture in mouse oocyte. Oncotarget. 2017;8:39012-39020 pubmed publisher
Matějů D, Franzmann T, Patel A, Kopach A, Boczek E, Maharana S, et al. An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function. EMBO J. 2017;36:1669-1687 pubmed publisher
Messina G, Atterrato M, Prozzillo Y, Piacentini L, Losada A, Dimitri P. The human Cranio Facial Development Protein 1 (Cfdp1) gene encodes a protein required for the maintenance of higher-order chromatin organization. Sci Rep. 2017;7:45022 pubmed publisher
Filipescu D, Naughtin M, Podsypanina K, Lejour V, Wilson L, Gurard Levin Z, et al. Essential role for centromeric factors following p53 loss and oncogenic transformation. Genes Dev. 2017;31:463-480 pubmed publisher
Peng B, Shi R, Jiang W, Ding Y, Dong M, Zhu W, et al. Phosphorylation of LSD1 by PLK1 promotes its chromatin release during mitosis. Cell Biosci. 2017;7:15 pubmed publisher
Rai U, Najm F, Tartakoff A. Nucleolar asymmetry and the importance of septin integrity upon cell cycle arrest. PLoS ONE. 2017;12:e0174306 pubmed publisher
Strøm T, Laerdahl J, Leren T. Mutations affecting the transmembrane domain of the LDL receptor: impact of charged residues on the membrane insertion. Hum Mol Genet. 2017;26:1634-1642 pubmed publisher
Mao J, Xia Q, Liu C, Ying Z, Wang H, Wang G. A critical role of Hrd1 in the regulation of optineurin degradation and aggresome formation. Hum Mol Genet. 2017;26:1877-1889 pubmed publisher
Mosalaganti S, Keller J, Altenfeld A, Winzker M, Rombaut P, Saur M, et al. Structure of the RZZ complex and molecular basis of its interaction with Spindly. J Cell Biol. 2017;216:961-981 pubmed publisher
Huang C, Wu D, Jiao X, Khan F, Xiong C, Liu X, et al. Maternal SENP7 programs meiosis architecture and embryo survival in mouse. Biochim Biophys Acta Mol Cell Res. 2017;1864:1195-1206 pubmed publisher
Takeuchi S, Kasamatsu A, Yamatoji M, Nakashima D, Endo Sakamoto Y, Koide N, et al. TEAD4-YAP interaction regulates tumoral growth by controlling cell-cycle arrest at the G1 phase. Biochem Biophys Res Commun. 2017;486:385-390 pubmed publisher
Wheelock M, Wynne D, Tseng B, Funabiki H. Dual recognition of chromatin and microtubules by INCENP is important for mitotic progression. J Cell Biol. 2017;216:925-941 pubmed publisher
Varadaraj A, JENKINS L, Singh P, Chanda A, Snider J, Lee N, et al. TGF-β triggers rapid fibrillogenesis via a novel TβRII-dependent fibronectin-trafficking mechanism. Mol Biol Cell. 2017;28:1195-1207 pubmed publisher
Gigant E, Stefanutti M, Laband K, Gluszek Kustusz A, Edwards F, Lacroix B, et al. Inhibition of ectopic microtubule assembly by the kinesin-13 KLP-7 prevents chromosome segregation and cytokinesis defects in oocytes. Development. 2017;144:1674-1686 pubmed publisher
Kadeer A, Maruyama T, Kajita M, Morita T, Sasaki A, Ohoka A, et al. Plectin is a novel regulator for apical extrusion of RasV12-transformed cells. Sci Rep. 2017;7:44328 pubmed publisher
Mason J, Wei X, Fletcher G, Kiarash R, Brokx R, Hodgson R, et al. Functional characterization of CFI-402257, a potent and selective Mps1/TTK kinase inhibitor, for the treatment of cancer. Proc Natl Acad Sci U S A. 2017;114:3127-3132 pubmed publisher
Xu P, Zhou Z, Xiong M, Zou W, Deng X, Ganaie S, et al. Parvovirus B19 NS1 protein induces cell cycle arrest at G2-phase by activating the ATR-CDC25C-CDK1 pathway. PLoS Pathog. 2017;13:e1006266 pubmed publisher
Li M, Li S, Liu B, Gu M, Zou S, Xiao B, et al. PIG3 promotes NSCLC cell mitotic progression and is associated with poor prognosis of NSCLC patients. J Exp Clin Cancer Res. 2017;36:39 pubmed publisher
Silva P, Ribeiro N, Lima R, Andrade C, Diogo V, Teixeira J, et al. Suppression of spindly delays mitotic exit and exacerbates cell death response of cancer cells treated with low doses of paclitaxel. Cancer Lett. 2017;394:33-42 pubmed publisher
Wang Z, Zhong T, Wang Y, Song F, Yu X, Xing L, et al. Human Enterovirus 68 Interferes with the Host Cell Cycle to Facilitate Viral Production. Front Cell Infect Microbiol. 2017;7:29 pubmed publisher
Liu Y, Cussiol J, Dibitetto D, Sims J, Twayana S, Weiss R, et al. TOPBP1Dpb11 plays a conserved role in homologous recombination DNA repair through the coordinated recruitment of 53BP1Rad9. J Cell Biol. 2017;216:623-639 pubmed publisher
Risal S, Zhang J, Adhikari D, Liu X, Shao J, Hu M, et al. MASTL is essential for anaphase entry of proliferating primordial germ cells and establishment of female germ cells in mice. Cell Discov. 2017;3:16052 pubmed publisher
Huang J, Ku W, Chen Y, Chang Y, Chu C. Dual mechanisms regulate the nucleocytoplasmic localization of human DDX6. Sci Rep. 2017;7:42853 pubmed publisher
Cheng L, Yang Q, Li C, Dai L, Yang Y, Wang Q, et al. DDA1, a novel oncogene, promotes lung cancer progression through regulation of cell cycle. J Cell Mol Med. 2017;21:1532-1544 pubmed publisher
Shumilov A, Tsai M, Schlosser Y, Kratz A, Bernhardt K, Fink S, et al. Epstein-Barr virus particles induce centrosome amplification and chromosomal instability. Nat Commun. 2017;8:14257 pubmed publisher
Tu Y, Liu H, Zhu X, Shen H, Ma X, Wang F, et al. Ataxin-3 promotes genome integrity by stabilizing Chk1. Nucleic Acids Res. 2017;45:4532-4549 pubmed publisher
Gache V, Gomes E, Cadot B. Microtubule motors involved in nuclear movement during skeletal muscle differentiation. Mol Biol Cell. 2017;28:865-874 pubmed publisher
Huang R, Zhu G, Zhang J, Lai Y, Xu Y, He J, et al. Betanodavirus-like particles enter host cells via clathrin-mediated endocytosis in a cholesterol-, pH- and cytoskeleton-dependent manner. Vet Res. 2017;48:8 pubmed publisher
Vashi N, Andrabi S, Ghanwat S, Suar M, Kumar D. Ca2+-dependent Focal Exocytosis of Golgi-derived Vesicles Helps Phagocytic Uptake in Macrophages. J Biol Chem. 2017;292:5144-5165 pubmed publisher
Wan L, Chen M, Cao J, Dai X, Yin Q, Zhang J, et al. The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function. Cancer Discov. 2017;7:424-441 pubmed publisher
Wang J, Lee J, Christian S, Dang Lawson M, Pritchard C, Freeman S, et al. The Rap1-cofilin-1 pathway coordinates actin reorganization and MTOC polarization at the B cell immune synapse. J Cell Sci. 2017;130:1094-1109 pubmed publisher
Yun C, Bhargava P, Na Y, Lee J, Ryu J, Kaul S, et al. Relevance of mortalin to cancer cell stemness and cancer therapy. Sci Rep. 2017;7:42016 pubmed publisher
Jacobs K, Van de Velde H, de Paepe C, Sermon K, Spits C. Mitotic spindle disruption in human preimplantation embryos activates the spindle assembly checkpoint but not apoptosis until Day 5 of development. Mol Hum Reprod. 2017;23:321-329 pubmed publisher
Fava L, Schüler F, Sladky V, Haschka M, Soratroi C, Eiterer L, et al. The PIDDosome activates p53 in response to supernumerary centrosomes. Genes Dev. 2017;31:34-45 pubmed publisher
Wong M, Gillingham A, Munro S. The golgin coiled-coil proteins capture different types of transport carriers via distinct N-terminal motifs. BMC Biol. 2017;15:3 pubmed publisher
Hoppe Seyler K, Bossler F, Lohrey C, Bulkescher J, Rösl F, Jansen L, et al. Induction of dormancy in hypoxic human papillomavirus-positive cancer cells. Proc Natl Acad Sci U S A. 2017;114:E990-E998 pubmed publisher
Wang S, Willenberg I, Krohn M, Hecker T, Meckelmann S, Li C, et al. Growth-Inhibiting Activity of Resveratrol Imine Analogs on Tumor Cells In Vitro. PLoS ONE. 2017;12:e0170502 pubmed publisher
Kinoshita E, Kinoshita Kikuta E, Karata K, Kawano T, Nishiyama A, Yamato M, et al. Specific glutamic acid residues in targeted proteins induce exaggerated retardations in Phos-tag SDS-PAGE migration. Electrophoresis. 2017;38:1139-1146 pubmed publisher
Faesen A, Thanasoula M, Maffini S, Breit C, Müller F, van Gerwen S, et al. Basis of catalytic assembly of the mitotic checkpoint complex. Nature. 2017;542:498-502 pubmed publisher
Ruf S, Heberle A, Langelaar Makkinje M, Gelino S, Wilkinson D, Gerbeth C, et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy. 2017;13:486-505 pubmed publisher
Inoue D, Stemmer M, Thumberger T, Ruppert T, Bärenz F, Wittbrodt J, et al. Expression of the novel maternal centrosome assembly factor Wdr8 is required for vertebrate embryonic mitoses. Nat Commun. 2017;8:14090 pubmed publisher
Hatch R, Wei Y, Xia D, Götz J. Hyperphosphorylated tau causes reduced hippocampal CA1 excitability by relocating the axon initial segment. Acta Neuropathol. 2017;133:717-730 pubmed publisher
Kim H, Johnson J, Lera R, Brahma S, Burkard M. Anillin Phosphorylation Controls Timely Membrane Association and Successful Cytokinesis. PLoS Genet. 2017;13:e1006511 pubmed publisher
Rivera Serrano E, Fritch E, Scholl E, Sherry B. A Cytoplasmic RNA Virus Alters the Function of the Cell Splicing Protein SRSF2. J Virol. 2017;91: pubmed publisher
Hu H, Zhang H, Wang S, Ding M, An H, Hou Y, et al. Live visualization of genomic loci with BiFC-TALE. Sci Rep. 2017;7:40192 pubmed publisher
Guo X, Ni J, Xue J, Wang X. Extract of bulbus Fritillaria cirrhosa perturbs spindle assembly checkpoint, induces mitotic aberrations and genomic instability in human colon epithelial cell line. Exp Toxicol Pathol. 2017;69:163-171 pubmed publisher
Shahbazi M, Peña Jimenez D, Antonucci F, Drosten M, Perez Moreno M. Clasp2 ensures mitotic fidelity and prevents differentiation of epidermal keratinocytes. J Cell Sci. 2017;130:683-688 pubmed publisher
Wei T, Wu P, Wu T, Hou H, Chou W, Teng C, et al. Aurora A and NF-κB Survival Pathway Drive Chemoresistance in Acute Myeloid Leukemia via the TRAF-Interacting Protein TIFA. Cancer Res. 2017;77:494-508 pubmed publisher
Liu X, Gao Y, Ye H, Gerrin S, Ma F, Wu Y, et al. Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer. Nucleic Acids Res. 2017;45:3738-3751 pubmed publisher
Kumar A, Kim J, Ranjan P, Metcalfe M, Cao W, Mishina M, et al. Influenza virus exploits tunneling nanotubes for cell-to-cell spread. Sci Rep. 2017;7:40360 pubmed publisher
Abadía Molina F, Morón Calvente V, Baird S, Shamim F, Martin F, MacKenzie A. Neuronal apoptosis inhibitory protein (NAIP) localizes to the cytokinetic machinery during cell division. Sci Rep. 2017;7:39981 pubmed publisher
Blank H, Perez R, He C, Maitra N, Metz R, Hill J, et al. Translational control of lipogenic enzymes in the cell cycle of synchronous, growing yeast cells. EMBO J. 2017;36:487-502 pubmed publisher
Lima S, Milstien S, Spiegel S. Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking. J Biol Chem. 2017;292:3074-3088 pubmed publisher
Jemaà M, Abdallah S, Lledo G, Perrot G, Lesluyes T, Teyssier C, et al. Heterogeneity in sarcoma cell lines reveals enhanced motility of tetraploid versus diploid cells. Oncotarget. 2017;8:16669-16689 pubmed publisher
Araujo T, Zeidler J, Oliveira P, Dias M, Armelin H, Laurindo F. Protein disulfide isomerase externalization in endothelial cells follows classical and unconventional routes. Free Radic Biol Med. 2017;103:199-208 pubmed publisher
Zhang Y, Tang X, Shi M, Wen C, Shen B. MiR-216a decreases MALAT1 expression, induces G2/M arrest and apoptosis in pancreatic cancer cells. Biochem Biophys Res Commun. 2017;483:816-822 pubmed publisher
Noguchi K, Hongama K, Hariki S, Nonomiya Y, Katayama K, Sugimoto Y. Functional Effects of AKT3 on Aurora Kinase Inhibitor-induced Aneuploidy. J Biol Chem. 2017;292:1910-1924 pubmed publisher
Li D, Liu X, Zhou J, Hu J, Zhang D, Liu J, et al. Long noncoding RNA HULC modulates the phosphorylation of YB-1 through serving as a scaffold of extracellular signal-regulated kinase and YB-1 to enhance hepatocarcinogenesis. Hepatology. 2017;65:1612-1627 pubmed publisher
Reyes A, Hop H, Arayan L, Huy T, Min W, Lee H, et al. Nocodazole treatment interrupted Brucella abortus invasion in RAW 264.7 cells, and successfully attenuated splenic proliferation with enhanced inflammatory response in mice. Microb Pathog. 2017;103:87-93 pubmed publisher
Wang G, Dong Q, Bai Y, Yuan J, Xu Q, Cao C, et al. Oxidative stress induces mitotic arrest by inhibiting Aurora A-involved mitotic spindle formation. Free Radic Biol Med. 2017;103:177-187 pubmed publisher
Sun Y, Dong L, Yu S, Wang X, Zheng H, Zhang P, et al. Newcastle disease virus induces stable formation of bona fide stress granules to facilitate viral replication through manipulating host protein translation. FASEB J. 2017;31:1337-1353 pubmed publisher
Gieseler Halbach S, Meltendorf S, Pierau M, Weinert S, Heidel F, Fischer T, et al. RSK-mediated nuclear accumulation of the cold-shock Y-box protein-1 controls proliferation of T cells and T-ALL blasts. Cell Death Differ. 2017;24:371-383 pubmed publisher
Ho S, Rao R, To S, Schoch E, Tarapore P. Bisphenol A and its analogues disrupt centrosome cycle and microtubule dynamics in prostate cancer. Endocr Relat Cancer. 2017;24:83-96 pubmed publisher
Wang Q, Kieffer Kwon K, Oliveira T, Mayer C, Yao K, Pai J, et al. The cell cycle restricts activation-induced cytidine deaminase activity to early G1. J Exp Med. 2017;214:49-58 pubmed publisher
Wang X, Sehgal L, Jain N, Khashab T, Mathur R, Samaniego F. LncRNA MALAT1 promotes development of mantle cell lymphoma by associating with EZH2. J Transl Med. 2016;14:346 pubmed publisher
Batsir S, Geiger B, Kam Z. Dynamics of the sealing zone in cultured osteoclasts. Cytoskeleton (Hoboken). 2017;74:72-81 pubmed publisher
Tripathi E, Smith S. Cell cycle-regulated ubiquitination of tankyrase 1 by RNF8 and ABRO1/BRCC36 controls the timing of sister telomere resolution. EMBO J. 2017;36:503-519 pubmed publisher
Bertocchi C, Wang Y, Ravasio A, Hara Y, Wu Y, Sailov T, et al. Nanoscale architecture of cadherin-based cell adhesions. Nat Cell Biol. 2017;19:28-37 pubmed publisher
Chen M, Liu Y, Wang Y, Liu R, Xu B, Zhang F, et al. KIF2A regulates the spindle assembly and the metaphase I-anaphase I transition in mouse oocyte. Sci Rep. 2016;6:39337 pubmed publisher
Cheeseman L, Boulanger J, Bond L, Schuh M. Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes. Nat Commun. 2016;7:13726 pubmed publisher
Tumini E, Barroso S, Calero C, Aguilera A. Roles of human POLD1 and POLD3 in genome stability. Sci Rep. 2016;6:38873 pubmed publisher
Caron D, Byrne D, Thebault P, Soulet D, Landry C, Eyers P, et al. Mitotic phosphotyrosine network analysis reveals that tyrosine phosphorylation regulates Polo-like kinase 1 (PLK1). Sci Signal. 2016;9:rs14 pubmed
Watanabe K, Bizen N, Sato N, Takebayashi H. Endoplasmic Reticulum-Localized Transmembrane Protein Dpy19L1 Is Required for Neurite Outgrowth. PLoS ONE. 2016;11:e0167985 pubmed publisher
Zhao J, Chen X, Song G, Zhang J, Liu H, Liu X. Uhrf1 controls the self-renewal versus differentiation of hematopoietic stem cells by epigenetically regulating the cell-division modes. Proc Natl Acad Sci U S A. 2017;114:E142-E151 pubmed publisher
Méndez Olvera E, Bustos Martínez J, Lopez Vidal Y, Verdugo Rodríguez A, Martínez Gómez D. Cytolethal Distending Toxin From Campylobacter jejuni Requires the Cytoskeleton for Toxic Activity. Jundishapur J Microbiol. 2016;9:e35591 pubmed
Nüße J, Blumrich E, Mirastschijski U, Kappelmann L, Kelm S, Dietz F. Intra- or extra-exosomal secretion of HDGF isoforms: the extraordinary function of the HDGF-A N-terminal peptide. Biol Chem. 2017;398:793-811 pubmed publisher
Seo M, Lee S, Kim J, Hong Y, Kim S, Kim Y, et al. MAP4-regulated dynein-dependent trafficking of BTN3A1 controls the TBK1-IRF3 signaling axis. Proc Natl Acad Sci U S A. 2016;113:14390-14395 pubmed
Phengchat R, Takata H, Morii K, Inada N, Murakoshi H, Uchiyama S, et al. Calcium ions function as a booster of chromosome condensation. Sci Rep. 2016;6:38281 pubmed publisher
Jo U, Cai W, Wang J, Kwon Y, D Andrea A, Kim H. PCNA-Dependent Cleavage and Degradation of SDE2 Regulates Response to Replication Stress. PLoS Genet. 2016;12:e1006465 pubmed publisher
Rodriguez J, Lee L, Lynch B, Tsukiyama T. Nucleosome occupancy as a novel chromatin parameter for replication origin functions. Genome Res. 2017;27:269-277 pubmed publisher
Cui C, Zang T, Cao Y, Qin X, Zhang X. CDC25B is involved in the centrosomal microtubule nucleation in two-cell stage mouse embryos. Dev Growth Differ. 2016;58:714-726 pubmed publisher
Qu Y, Hahn I, Webb S, Pearce S, Prokop A. Periodic actin structures in neuronal axons are required to maintain microtubules. Mol Biol Cell. 2017;28:296-308 pubmed publisher
Juks C, Lorents A, Arukuusk P, Langel U, Pooga M. Cell-penetrating peptides recruit type A scavenger receptors to the plasma membrane for cellular delivery of nucleic acids. FASEB J. 2017;31:975-988 pubmed publisher
Chang Y, Chiu C, Yuo C, Chan W, Chang Y, Chang W, et al. An XIST-related small RNA regulates KRAS G-quadruplex formation beyond X-inactivation. Oncotarget. 2016;7:86713-86729 pubmed publisher
Yuan H, Sehgal P. MxA Is a Novel Regulator of Endosome-Associated Transcriptional Signaling by Bone Morphogenetic Proteins 4 and 9 (BMP4 and BMP9). PLoS ONE. 2016;11:e0166382 pubmed publisher
Kaufmann T, Kukolj E, Brachner A, Beltzung E, Bruno M, Kostrhon S, et al. SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation. J Cell Sci. 2016;129:4607-4621 pubmed
Zhang C, Zhou L, Zhang F, Lu D, Li N, Zheng L, et al. Mechanical remodeling of normally sized mammalian cells under a gravity vector. FASEB J. 2017;31:802-813 pubmed publisher
Portugal L, Muñóz Garay C, Martínez de Castro D, Soberon M, Bravo A. Toxicity of Cry1A toxins from Bacillus thuringiensis to CF1 cells does not involve activation of adenylate cyclase/PKA signaling pathway. Insect Biochem Mol Biol. 2017;80:21-31 pubmed publisher
Di Genova B, da Silva R, da Cunha J, Gargantini P, Mortara R, Tonelli R. Protein SUMOylation is Involved in Cell-cycle Progression and Cell Morphology in Giardia lamblia. J Eukaryot Microbiol. 2017;64:491-503 pubmed publisher
Silva R, Sattlegger E, Castilho B. Perturbations in actin dynamics reconfigure protein complexes that modulate GCN2 activity and promote an eIF2 response. J Cell Sci. 2016;129:4521-4533 pubmed
Rasmussen R, Gajjar M, Tučková L, Jensen K, Maya Mendoza A, Holst C, et al. BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity. Nat Commun. 2016;7:13398 pubmed publisher
Wang J, Zhang H, Zhang X, Wang P, Wang H, Huang F, et al. PC-1 works in conjunction with E3 ligase CHIP to regulate androgen receptor stability and activity. Oncotarget. 2016;7:81377-81388 pubmed publisher
Shyian M, Mattarocci S, Albert B, Hafner L, Lezaja A, Costanzo M, et al. Budding Yeast Rif1 Controls Genome Integrity by Inhibiting rDNA Replication. PLoS Genet. 2016;12:e1006414 pubmed publisher
Roussel Gervais A, Naciri I, Kirsh O, Kasprzyk L, Velasco G, Grillo G, et al. Loss of the Methyl-CpG-Binding Protein ZBTB4 Alters Mitotic Checkpoint, Increases Aneuploidy, and Promotes Tumorigenesis. Cancer Res. 2017;77:62-73 pubmed publisher
Hu Y, Kim J, He K, Wan Q, Kim J, Flach M, et al. Scramblase TMEM16F terminates T cell receptor signaling to restrict T cell exhaustion. J Exp Med. 2016;213:2759-2772 pubmed
Ugarte Uribe B, Grijalvo S, Pertíñez S, Busto J, Martin C, Alagia A, et al. Lipid-modified oligonucleotide conjugates: Insights into gene silencing, interaction with model membranes and cellular uptake mechanisms. Bioorg Med Chem. 2017;25:175-186 pubmed publisher
Parreno J, Nabavi Niaki M, Andrejevic K, Jiang A, Wu P, Kandel R. Interplay between cytoskeletal polymerization and the chondrogenic phenotype in chondrocytes passaged in monolayer culture. J Anat. 2017;230:234-248 pubmed publisher
Villeneuve J, Duran J, Scarpa M, Bassaganyas L, van Galen J, Malhotra V. Golgi enzymes do not cycle through the endoplasmic reticulum during protein secretion or mitosis. Mol Biol Cell. 2017;28:141-151 pubmed publisher
Liu Q, Tang Y, Chen L, Liu N, Lang F, Liu H, et al. E3 Ligase SCF?TrCP-induced DYRK1A Protein Degradation Is Essential for Cell Cycle Progression in HEK293 Cells. J Biol Chem. 2016;291:26399-26409 pubmed
Noordstra I, Liu Q, Nijenhuis W, Hua S, Jiang K, Baars M, et al. Control of apico-basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7. J Cell Sci. 2016;129:4278-4288 pubmed
Mimura Y, Takagi M, Clever M, Imamoto N. ELYS regulates the localization of LBR by modulating its phosphorylation state. J Cell Sci. 2016;129:4200-4212 pubmed
Dugardin C, Briand O, Touche V, Schonewille M, Moreau F, Le May C, et al. Retrograde cholesterol transport in the human Caco-2/TC7 cell line: a model to study trans-intestinal cholesterol excretion in atherogenic and diabetic dyslipidemia. Acta Diabetol. 2017;54:191-199 pubmed publisher
Zhang T, Si Hoe S, Hudson D, Surana U. Condensin recruitment to chromatin is inhibited by Chk2 kinase in response to DNA damage. Cell Cycle. 2016;15:3454-3470 pubmed publisher
Yu X, Zhao Q, Wang X, Zhang J, Wang X. Gambogenic acid induces proteasomal degradation of CIP2A and sensitizes hepatocellular carcinoma to anticancer agents. Oncol Rep. 2016;36:3611-3618 pubmed publisher
Kwon S, Oh S, Nacke M, Mostov K, Lipschutz J. Adaptor Protein CD2AP and L-type Lectin LMAN2 Regulate Exosome Cargo Protein Trafficking through the Golgi Complex. J Biol Chem. 2016;291:25462-25475 pubmed
Levrier C, Sadowski M, Rockstroh A, Gabrielli B, Kavallaris M, Lehman M, et al. 6α-Acetoxyanopterine: A Novel Structure Class of Mitotic Inhibitor Disrupting Microtubule Dynamics in Prostate Cancer Cells. Mol Cancer Ther. 2017;16:3-15 pubmed publisher
Hong M, Ren M, Silva J, Paul A, Wilson W, Schroeder C, et al. YM155 inhibits topoisomerase function. Anticancer Drugs. 2017;28:142-152 pubmed publisher
Kratz A, Richter K, Schlosser Y, Schmitt M, Shumilov A, Delecluse H, et al. Fbxo28 promotes mitotic progression and regulates topoisomerase II?-dependent DNA decatenation. Cell Cycle. 2016;15:3419-3431 pubmed publisher
Nikolic J, Civas A, Lama Z, Lagaudrière Gesbert C, Blondel D. Rabies Virus Infection Induces the Formation of Stress Granules Closely Connected to the Viral Factories. PLoS Pathog. 2016;12:e1005942 pubmed publisher
Liu C, Hsieh C, Kim S, Wang J, Ni Y, Su C, et al. An indolylquinoline derivative activates DNA damage response and apoptosis in human hepatocellular carcinoma cells. Int J Oncol. 2016;49:2431-2441 pubmed publisher
Kawaguchi K, Kikuma T, Higuchi Y, Takegawa K, Kitamoto K. Subcellular localization of acyl-CoA binding protein in Aspergillus oryzae is regulated by autophagy machinery. Biochem Biophys Res Commun. 2016;480:8-12 pubmed publisher
Bruinsma W, Aprelia M, García Santisteban I, Kool J, Xu Y, Medema R. Inhibition of Polo-like kinase 1 during the DNA damage response is mediated through loss of Aurora A recruitment by Bora. Oncogene. 2017;36:1840-1848 pubmed publisher
Wu J, He Z, Wang D, Sun F. Depletion of JMJD5 sensitizes tumor cells to microtubule-destabilizing agents by altering microtubule stability. Cell Cycle. 2016;15:2980-2991 pubmed
Lewis C, Golsteyn R. Cancer cells that survive checkpoint adaptation contain micronuclei that harbor damaged DNA. Cell Cycle. 2016;15:3131-3145 pubmed
Mulvaney K, Matson J, Siesser P, Tamir T, Goldfarb D, Jacobs T, et al. Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate. J Biol Chem. 2016;291:23719-23733 pubmed
Garvanska D, Larsen M, Nilsson J. Synergistic inhibition of the APC/C by the removal of APC15 in HCT116 cells lacking UBE2C. Biol Open. 2016;5:1441-1448 pubmed publisher
Roman J, Reucroft I, Martin R, Hurtado A, Mao H. Local Release of Paclitaxel from Aligned, Electrospun Microfibers Promotes Axonal Extension. Adv Healthc Mater. 2016;5:2628-2635 pubmed publisher
Rawal C, Riccardo S, Pesenti C, Ferrari M, Marini F, Pellicioli A. Reduced kinase activity of polo kinase Cdc5 affects chromosome stability and DNA damage response in S. cerevisiae. Cell Cycle. 2016;15:2906-2919 pubmed
Simard Bisson C, Bidoggia J, Larouche D, Guérin S, Blouin R, Hirai S, et al. A Role for DLK in Microtubule Reorganization to the Cell Periphery and in the Maintenance of Desmosomal and Tight Junction Integrity. J Invest Dermatol. 2017;137:132-141 pubmed publisher
Schäfer M, Bellouze S, Jacquier A, Schaller S, Richard L, Mathis S, et al. Sensory neuropathy in progressive motor neuronopathy (pmn) mice is associated with defects in microtubule polymerization and axonal transport. Brain Pathol. 2017;27:459-471 pubmed publisher
Amanullah A, Upadhyay A, Chhangani D, Joshi V, Mishra R, Yamanaka K, et al. Proteasomal Dysfunction Induced By Diclofenac Engenders Apoptosis Through Mitochondrial Pathway. J Cell Biochem. 2017;118:1014-1027 pubmed publisher
Eymery A, Liu Z, Ozonov E, Stadler M, Peters A. The methyltransferase Setdb1 is essential for meiosis and mitosis in mouse oocytes and early embryos. Development. 2016;143:2767-79 pubmed publisher
Vilmont V, Cadot B, Vezin E, Le Grand F, Gomes E. Dynein disruption perturbs post-synaptic components and contributes to impaired MuSK clustering at the NMJ: implication in ALS. Sci Rep. 2016;6:27804 pubmed publisher
Wang P, Liu H, Wang Y, Liu O, Zhang J, Gleason A, et al. RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling Endosomes. PLoS Genet. 2016;12:e1006093 pubmed publisher
Mitton B, Chae H, Hsu K, Dutta R, Aldana Masangkay G, Ferrari R, et al. Small molecule inhibition of cAMP response element binding protein in human acute myeloid leukemia cells. Leukemia. 2016;30:2302-2311 pubmed publisher
Aravamudhan P, Chen R, Roy B, Sim J, Joglekar A. Dual mechanisms regulate the recruitment of spindle assembly checkpoint proteins to the budding yeast kinetochore. Mol Biol Cell. 2016;27:3405-3417 pubmed
Meng F, Qian J, Yue H, Li X, Xue K. SUMOylation of Rb enhances its binding with CDK2 and phosphorylation at early G1 phase. Cell Cycle. 2016;15:1724-32 pubmed publisher
Reinhard N, van Helden S, Anthony E, Yin T, Wu Y, Goedhart J, et al. Spatiotemporal analysis of RhoA/B/C activation in primary human endothelial cells. Sci Rep. 2016;6:25502 pubmed publisher
Acebes Huerta A, Lorenzo Herrero S, Folgueras A, Huergo Zapico L, Lopez Larrea C, Lopez Soto A, et al. Drug-induced hyperploidy stimulates an antitumor NK cell response mediated by NKG2D and DNAM-1 receptors. Oncoimmunology. 2016;5:e1074378 pubmed
Hasanpourghadi M, Karthikeyan C, Pandurangan A, Looi C, Trivedi P, Kobayashi K, et al. Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell. J Exp Clin Cancer Res. 2016;35:58 pubmed publisher
Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, et al. Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability. Nat Commun. 2016;7:11117 pubmed publisher
Bolton H, Graham S, van der Aa N, Kumar P, Theunis K, Fernandez Gallardo E, et al. Mouse model of chromosome mosaicism reveals lineage-specific depletion of aneuploid cells and normal developmental potential. Nat Commun. 2016;7:11165 pubmed publisher
Hilbert M, Noga A, Frey D, Hamel V, Guichard P, Kraatz S, et al. SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. Nat Cell Biol. 2016;18:393-403 pubmed publisher
Obino D, Farina F, Malbec O, Sáez P, Maurin M, Gaillard J, et al. Actin nucleation at the centrosome controls lymphocyte polarity. Nat Commun. 2016;7:10969 pubmed publisher
Morikawa T, Fujita H, Kitamura A, Horio T, Yamamoto J, Kinjo M, et al. Dependence of fluorescent protein brightness on protein concentration in solution and enhancement of it. Sci Rep. 2016;6:22342 pubmed publisher
Schulte C, Rodighiero S, Cappelluti M, Puricelli L, Maffioli E, Borghi F, et al. Conversion of nanoscale topographical information of cluster-assembled zirconia surfaces into mechanotransductive events promotes neuronal differentiation. J Nanobiotechnology. 2016;14:18 pubmed publisher
Chimge N, Little G, Baniwal S, Adisetiyo H, Xie Y, Zhang T, et al. RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer. Nat Commun. 2016;7:10751 pubmed publisher
Jiang X, Wang J, Xing L, Shen H, Lian W, Yi L, et al. Sterigmatocystin-induced checkpoint adaptation depends on Chk1 in immortalized human gastric epithelial cells in vitro. Arch Toxicol. 2017;91:259-270 pubmed publisher
Huang Y, Hoffmann G, Wheeler B, Schiapparelli P, Quinones Hinojosa A, Searson P. Cellular microenvironment modulates the galvanotaxis of brain tumor initiating cells. Sci Rep. 2016;6:21583 pubmed publisher
Ho M, Huang L, Goodwin J, Dong X, Chen C, Xie H. Two Small Molecules Block Oral Epithelial Cell Invasion by Porphyromons gingivalis. PLoS ONE. 2016;11:e0149618 pubmed publisher
Vituret C, Gallay K, Confort M, Ftaich N, Matei C, Archer F, et al. Transfer of the Cystic Fibrosis Transmembrane Conductance Regulator to Human Cystic Fibrosis Cells Mediated by Extracellular Vesicles. Hum Gene Ther. 2016;27:166-83 pubmed publisher
Boekhout M, Yuan R, Wondergem A, Segeren H, van Liere E, Awol N, et al. Feedback regulation between atypical E2Fs and APC/CCdh1 coordinates cell cycle progression. EMBO Rep. 2016;17:414-27 pubmed publisher
Wike C, Graves H, Hawkins R, Gibson M, Ferdinand M, Zhang T, et al. Aurora-A mediated histone H3 phosphorylation of threonine 118 controls condensin I and cohesin occupancy in mitosis. elife. 2016;5:e11402 pubmed publisher
Maiden S, Petrova Y, Gumbiner B. Microtubules Inhibit E-Cadherin Adhesive Activity by Maintaining Phosphorylated p120-Catenin in a Colon Carcinoma Cell Model. PLoS ONE. 2016;11:e0148574 pubmed publisher
Ghosh D, Pinto S, Danglot L, Vandewauw I, Segal A, Van Ranst N, et al. VAMP7 regulates constitutive membrane incorporation of the cold-activated channel TRPM8. Nat Commun. 2016;7:10489 pubmed publisher
Dos Santos E, Carneiro Lobo T, Aoki M, Levantini E, Bassères D. Aurora kinase targeting in lung cancer reduces KRAS-induced transformation. Mol Cancer. 2016;15:12 pubmed publisher
Signoretto E, Honisch S, Briglia M, Faggio C, Castagna M, Lang F. Nocodazole Induced Suicidal Death of Human Erythrocytes. Cell Physiol Biochem. 2016;38:379-92 pubmed publisher
He Y, Zeng M, Yang D, Motro B, Núñez G. NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux. Nature. 2016;530:354-7 pubmed publisher
Caly L, Kassouf V, Moseley G, Diefenbach R, Cunningham A, Jans D. Fast track, dynein-dependent nuclear targeting of human immunodeficiency virus Vpr protein; impaired trafficking in a clinical isolate. Biochem Biophys Res Commun. 2016;470:735-740 pubmed publisher
Arnaudo A, Link A, Garcia B. Bioorthogonal Chemistry for the Isolation and Study of Newly Synthesized Histones and Their Modifications. ACS Chem Biol. 2016;11:782-91 pubmed publisher
Jayachandran P, Olmo V, Sanchez S, McFarland R, Vital E, Werner J, et al. Microtubule-associated protein 1b is required for shaping the neural tube. Neural Dev. 2016;11:1 pubmed publisher
Zhang S, Duan L, Qian H, Yu X. Actin Aggregations Mark the Sites of Neurite Initiation. Neurosci Bull. 2016;32:1-15 pubmed publisher
Kuo C, Li X, Stark J, Shih H, Ann D. RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner. Cell Cycle. 2016;15:787-98 pubmed publisher
Acharya B, Espenel C, Libanje F, Raingeaud J, Morgan J, Jaulin F, et al. KIF17 regulates RhoA-dependent actin remodeling at epithelial cell-cell adhesions. J Cell Sci. 2016;129:957-70 pubmed publisher
Han S, Guo H, Sun S, Jin Y, Wei Y, Feng X, et al. Productive Entry of Foot-and-Mouth Disease Virus via Macropinocytosis Independent of Phosphatidylinositol 3-Kinase. Sci Rep. 2016;6:19294 pubmed publisher
Amouroux R, Nashun B, Shirane K, Nakagawa S, Hill P, D Souza Z, et al. De novo DNA methylation drives 5hmC accumulation in mouse zygotes. Nat Cell Biol. 2016;18:225-233 pubmed publisher
Anderson D, Whitney D, Hanson Smith V, Woznica A, Campodonico Burnett W, Volkman B, et al. Evolution of an ancient protein function involved in organized multicellularity in animals. elife. 2016;5:e10147 pubmed publisher
Libério M, Sadowski M, Davis R, Rockstroh A, Vasireddy R, Lehman M, et al. The ascidian natural product eusynstyelamide B is a novel topoisomerase II poison that induces DNA damage and growth arrest in prostate and breast cancer cells. Oncotarget. 2015;6:43944-63 pubmed publisher
Chaigne A, Campillo C, Voituriez R, Gov N, Sykes C, Verlhac M, et al. F-actin mechanics control spindle centring in the mouse zygote. Nat Commun. 2016;7:10253 pubmed publisher
Kennedy E, Dysart M, Lianga N, Williams E, Pilon S, Doré C, et al. Redundant Regulation of Cdk1 Tyrosine Dephosphorylation in Saccharomyces cerevisiae. Genetics. 2016;202:903-10 pubmed publisher
Makhija E, Jokhun D, Shivashankar G. Nuclear deformability and telomere dynamics are regulated by cell geometric constraints. Proc Natl Acad Sci U S A. 2016;113:E32-40 pubmed publisher
O Connor A, Maffini S, Rainey M, Kaczmarczyk A, Gaboriau D, Musacchio A, et al. Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint. Biol Open. 2015;5:11-9 pubmed publisher
Patil H, Wilks C, Gonzalez R, Dhanireddy S, Conrad Webb H, Bergel M. Mitotic Activation of a Novel Histone Deacetylase 3-Linker Histone H1.3 Protein Complex by Protein Kinase CK2. J Biol Chem. 2016;291:3158-72 pubmed publisher
Pillai S, Nguyen J, Johnson J, Haura E, Coppola D, Chellappan S. Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis. Nat Commun. 2015;6:10072 pubmed publisher
Guo X, Wang X, Wang Z, Banerjee S, Yang J, Huang L, et al. Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis. Nat Cell Biol. 2016;18:202-12 pubmed publisher
Foss K, Robeson A, Kornbluth S, Zhang L. Mitotic phosphatase activity is required for MCC maintenance during the spindle checkpoint. Cell Cycle. 2016;15:225-33 pubmed publisher
Grandy R, Whitfield T, Wu H, Fitzgerald M, VanOudenhove J, Zaidi S, et al. Genome-Wide Studies Reveal that H3K4me3 Modification in Bivalent Genes Is Dynamically Regulated during the Pluripotent Cell Cycle and Stabilized upon Differentiation. Mol Cell Biol. 2016;36:615-27 pubmed publisher
Nielsen C, Huttner D, Bizard A, Hirano S, Li T, Palmai Pallag T, et al. PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis. Nat Commun. 2015;6:8962 pubmed publisher
Jemaà M, Manic G, Lledo G, Lissa D, Reynès C, Morin N, et al. Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition. Oncotarget. 2016;7:885-901 pubmed publisher
Zhang Z, Ma J, Zhang X, Su C, Yao Q, Wang X. Equine Infectious Anemia Virus Gag Assembly and Export Are Directed by Matrix Protein through trans-Golgi Networks and Cellular Vesicles. J Virol. 2016;90:1824-38 pubmed publisher
Minocherhomji S, Ying S, Bjerregaard V, Bursomanno S, Aleliunaite A, Wu W, et al. Replication stress activates DNA repair synthesis in mitosis. Nature. 2015;528:286-90 pubmed publisher
Tauchman E, Boehm F, DeLuca J. Stable kinetochore-microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells. Nat Commun. 2015;6:10036 pubmed publisher
Dean P, Quitard S, Bulmer D, Roe A, Kenny B. Cultured enterocytes internalise bacteria across their basolateral surface for, pathogen-inhibitable, trafficking to the apical compartment. Sci Rep. 2015;5:17359 pubmed publisher
Sengupta P, Satpute Krishnan P, Seo A, Burnette D, Patterson G, Lippincott Schwartz J. ER trapping reveals Golgi enzymes continually revisit the ER through a recycling pathway that controls Golgi organization. Proc Natl Acad Sci U S A. 2015;112:E6752-61 pubmed publisher
Bélanger F, Angers J, Fortier Ã, Hammond Martel I, Costantino S, Drobetsky E, et al. Mutations in Replicative Stress Response Pathways Are Associated with S Phase-specific Defects in Nucleotide Excision Repair. J Biol Chem. 2016;291:522-37 pubmed publisher
Ferreira Barbosa J, Labrie J, Beaudry F, Gagnon C, Jacques M. Actinobacillus pleuropneumoniae induces SJPL cell cycle arrest in G2/M-phase and inhibits porcine reproductive and respiratory syndrome virus replication. Virol J. 2015;12:188 pubmed publisher
Elis E, Ehrlich M, Bacharach E. Dynamics and restriction of murine leukemia virus cores in mitotic and interphase cells. Retrovirology. 2015;12:95 pubmed publisher
Peitzman E, Zaidman N, Maniak P, O Grady S. Carvedilol binding to β2-adrenergic receptors inhibits CFTR-dependent anion secretion in airway epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2016;310:L50-8 pubmed publisher
Copeland S, Thurston S, Copeland J. Actin- and microtubule-dependent regulation of Golgi morphology by FHDC1. Mol Biol Cell. 2016;27:260-76 pubmed publisher
Xu C, Wang Y, Wang L, Wang Q, Du L, Fan S, et al. Accumulation and Phosphorylation of RecQ-Mediated Genome Instability Protein 1 (RMI1) at Serine 284 and Serine 292 during Mitosis. Int J Mol Sci. 2015;16:26395-405 pubmed publisher
Lui C, Ashton C, Sharma M, Brocardo M, Henderson B. APC functions at the centrosome to stimulate microtubule growth. Int J Biochem Cell Biol. 2016;70:39-47 pubmed publisher
Fan C, Chen L, Huang Q, Shen T, Welsh E, Teer J, et al. Overexpression of major CDKN3 transcripts is associated with poor survival in lung adenocarcinoma. Br J Cancer. 2015;113:1735-43 pubmed publisher
Okamoto A, Higo M, Shiiba M, Nakashima D, Koyama T, Miyamoto I, et al. Down-Regulation of Nucleolar and Spindle-Associated Protein 1 (NUSAP1) Expression Suppresses Tumor and Cell Proliferation and Enhances Anti-Tumor Effect of Paclitaxel in Oral Squamous Cell Carcinoma. PLoS ONE. 2015;10:e0142252 pubmed publisher
Guetta Terrier C, Monzo P, Zhu J, Long H, Venkatraman L, Zhou Y, et al. Protrusive waves guide 3D cell migration along nanofibers. J Cell Biol. 2015;211:683-701 pubmed publisher
Mori Y, Inoue Y, Taniyama Y, Tanaka S, Terada Y. Phosphorylation of the centrosomal protein, Cep169, by Cdk1 promotes its dissociation from centrosomes in mitosis. Biochem Biophys Res Commun. 2015;468:642-6 pubmed publisher
Hirano S, Kanno S. Macrophage Receptor with Collagenous Structure (MARCO) Is Processed by either Macropinocytosis or Endocytosis-Autophagy Pathway. PLoS ONE. 2015;10:e0142062 pubmed publisher
Villari G, Jayo A, Zanet J, Fitch B, Serrels B, Frame M, et al. A direct interaction between fascin and microtubules contributes to adhesion dynamics and cell migration. J Cell Sci. 2015;128:4601-14 pubmed publisher
Egervari K, Potter G, Guzmán Hernández M, Salmon P, Soto Ribeiro M, Kastberger B, et al. Astrocytes spatially restrict VEGF signaling by polarized secretion and incorporation of VEGF into the actively assembling extracellular matrix. Glia. 2016;64:440-56 pubmed publisher
Silva E, Betleja E, John E, Spear P, Moresco J, Zhang S, et al. Ccdc11 is a novel centriolar satellite protein essential for ciliogenesis and establishment of left-right asymmetry. Mol Biol Cell. 2016;27:48-63 pubmed publisher
Silva P, Tavares Ã, Bousbaa H. Co-silencing of human Bub3 and dynein highlights an antagonistic relationship in regulating kinetochore-microtubule attachments. FEBS Lett. 2015;589:3588-94 pubmed publisher
Broaders K, Cerchiari A, Gartner Z. Coupling between apical tension and basal adhesion allow epithelia to collectively sense and respond to substrate topography over long distances. Integr Biol (Camb). 2015;7:1611-21 pubmed publisher
Wong W, Kelly T, Li J, Ma H, Poon R. SGO1C is a non-functional isoform of Shugoshin and can disrupt sister chromatid cohesion by interacting with PP2A-B56. Cell Cycle. 2015;14:3965-77 pubmed publisher
Westmoreland J, Resnick M. Recombinational repair of radiation-induced double-strand breaks occurs in the absence of extensive resection. Nucleic Acids Res. 2016;44:695-704 pubmed publisher
Tsai Y, Itokazu Y, Yu R. GM1 Ganglioside is Involved in Epigenetic Activation Loci of Neuronal Cells. Neurochem Res. 2016;41:107-15 pubmed publisher
Segré C, Senese S, Loponte S, Santaguida S, Soffientini P, Grigorean G, et al. A monoclonal antibody specific for prophase phosphorylation of histone deacetylase 1: a readout for early mitotic cells. MAbs. 2016;8:37-42 pubmed publisher
Wang Y, Zhang H, Gigant B, Yu Y, Wu Y, Chen X, et al. Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery. FEBS J. 2016;283:102-11 pubmed publisher
Negishi T, Yasuo H. Distinct modes of mitotic spindle orientation align cells in the dorsal midline of ascidian embryos. Dev Biol. 2015;408:66-78 pubmed publisher
Coles G, Baglia L, Ackerman K. KIF7 Controls the Proliferation of Cells of the Respiratory Airway through Distinct Microtubule Dependent Mechanisms. PLoS Genet. 2015;11:e1005525 pubmed publisher
Castella M, Jacquemont C, Thompson E, Yeo J, Cheung R, Huang J, et al. FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2. PLoS Genet. 2015;11:e1005563 pubmed publisher
de Lange J, Faramarz A, Oostra A, de Menezes R, van der Meulen I, Rooimans M, et al. Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function. Nat Commun. 2015;6:8399 pubmed publisher
Yakovlev K. Localization of germ plasm-related structures during sea urchin oogenesis. Dev Dyn. 2016;245:56-66 pubmed publisher
Maeda M, Hasegawa H, Sugiyama M, Hyodo T, Ito S, Chen D, et al. Arginine methylation of ubiquitin-associated protein 2-like is required for the accurate distribution of chromosomes. FASEB J. 2016;30:312-23 pubmed publisher
Varela N, Aranguiz A, Lizama C, Sepulveda H, Antonelli M, Thaler R, et al. Mitotic Inheritance of mRNA Facilitates Translational Activation of the Osteogenic-Lineage Commitment Factor Runx2 in Progeny of Osteoblastic Cells. J Cell Physiol. 2016;231:1001-14 pubmed publisher
VanDeusen H, Kalejta R. Deficiencies in Cellular Processes Modulated by the Retinoblastoma Protein Do Not Account for Reduced Human Cytomegalovirus Replication in Its Absence. J Virol. 2015;89:11965-74 pubmed publisher
Katoh H, Nakatsu Y, Kubota T, Sakata M, Takeda M, Kidokoro M. Mumps Virus Is Released from the Apical Surface of Polarized Epithelial Cells, and the Release Is Facilitated by a Rab11-Mediated Transport System. J Virol. 2015;89:12026-34 pubmed publisher
Ojima K, Ichimura E, Yasukawa Y, Wakamatsu J, Nishimura T. Dynamics of myosin replacement in skeletal muscle cells. Am J Physiol Cell Physiol. 2015;309:C669-79 pubmed publisher
Das S, Borrman T, Liu V, Yang S, Bechhoefer J, Rhind N. Replication timing is regulated by the number of MCMs loaded at origins. Genome Res. 2015;25:1886-92 pubmed publisher
Egeland E, Boye K, Pettersen S, Haugen M, Øyjord T, Malerød L, et al. Enrichment of nuclear S100A4 during G2/M in colorectal cancer cells: possible association with cyclin B1 and centrosomes. Clin Exp Metastasis. 2015;32:755-67 pubmed publisher
Wei H, Wang Q, Du J, Li X, Zhang N, Cao Y, et al. Unique subcellular distribution of RPB1 with a phosphorylated C-terminal domain (CTD) in mouse oocytes during meiotic division and its relationship with chromosome separation. J Reprod Dev. 2015;61:541-8 pubmed publisher
Tamhane T, Lllukkumbura R, Lu S, Maelandsmo G, Haugen M, Brix K. Nuclear cathepsin L activity is required for cell cycle progression of colorectal carcinoma cells. Biochimie. 2016;122:208-18 pubmed publisher
Draga M, Madgett E, Vandenberg C, du Plessis D, Kaufmann A, Werler P, et al. BRCA1 Is Required for Maintenance of Phospho-Chk1 and G2/M Arrest during DNA Cross-Link Repair in DT40 Cells. Mol Cell Biol. 2015;35:3829-40 pubmed publisher
Zhuo X, Guo X, Zhang X, Jing G, Wang Y, Chen Q, et al. Usp16 regulates kinetochore localization of Plk1 to promote proper chromosome alignment in mitosis. J Cell Biol. 2015;210:727-35 pubmed publisher
Kashiwazaki A, Fujiwara Y, Tsuchiya H, Sakai N, Shibata K, Koshimizu T. Subcellular localization and internalization of the vasopressin V1B receptor. Eur J Pharmacol. 2015;765:291-9 pubmed publisher
Dale Rein I, Solberg Landsverk K, Micci F, Patzke S, Stokke T. Replication-induced DNA damage after PARP inhibition causes G2 delay, and cell line-dependent apoptosis, necrosis and multinucleation. Cell Cycle. 2015;14:3248-60 pubmed publisher
Lin W, Suo Y, Deng Y, Fan Z, Zheng Y, Wei X, et al. Morphological change of CD4(+) T cell during contact with DC modulates T-cell activation by accumulation of F-actin in the immunology synapse. BMC Immunol. 2015;16:49 pubmed publisher
Foster L, Ho S, Hook J, Basuki M, Marcal H. Chitosan as a Biomaterial: Influence of Degree of Deacetylation on Its Physiochemical, Material and Biological Properties. PLoS ONE. 2015;10:e0135153 pubmed publisher
Schweizer N, Pawar N, Weiss M, Maiato H. An organelle-exclusion envelope assists mitosis and underlies distinct molecular crowding in the spindle region. J Cell Biol. 2015;210:695-704 pubmed publisher
Movahedi Naini S, Sheridan A, Force T, Shah J, Bonventre J. Group IVA Cytosolic Phospholipase A2 Regulates the G2-to-M Transition by Modulating the Activity of Tumor Suppressor SIRT2. Mol Cell Biol. 2015;35:3768-84 pubmed publisher
DeBonis S, Neumann E, Skoufias D. Self protein-protein interactions are involved in TPPP/p25 mediated microtubule bundling. Sci Rep. 2015;5:13242 pubmed publisher
Li Y, Lovett D, Zhang Q, Neelam S, Kuchibhotla R, Zhu R, et al. Moving Cell Boundaries Drive Nuclear Shaping during Cell Spreading. Biophys J. 2015;109:670-86 pubmed publisher
Cervera L, Fuenmayor J, González Domínguez I, Gutiérrez Granados S, Segura M, Gòdia F. Selection and optimization of transfection enhancer additives for increased virus-like particle production in HEK293 suspension cell cultures. Appl Microbiol Biotechnol. 2015;99:9935-49 pubmed publisher
Kogel U, Gonzalez Suarez I, Xiang Y, Dossin E, Guy P, Mathis C, et al. Biological impact of cigarette smoke compared to an aerosol produced from a prototypic modified risk tobacco product on normal human bronchial epithelial cells. Toxicol In Vitro. 2015;29:2102-15 pubmed publisher
Haaß W, Kleiner H, Müller M, Hofmann W, Fabarius A, Seifarth W. Measurement of separase proteolytic activity in single living cells by a fluorogenic flow cytometry assay. PLoS ONE. 2015;10:e0133769 pubmed publisher
Lin P, Mobasher M, Hakakian Y, Kakarla V, Naseem A, Ziai H, et al. Differential requirements for H/ACA ribonucleoprotein components in cell proliferation and response to DNA damage. Histochem Cell Biol. 2015;144:543-58 pubmed publisher
Panet E, Ozer E, Mashriki T, Lazar I, Itzkovich D, Tzur A. Purifying Cytokinetic Cells from an Asynchronous Population. Sci Rep. 2015;5:13230 pubmed publisher
Tenorio M, Luchsinger C, Mardones G. Protein kinase A activity is necessary for fission and fusion of Golgi to endoplasmic reticulum retrograde tubules. PLoS ONE. 2015;10:e0135260 pubmed publisher
Sun D, Buttitta L. Protein phosphatase 2A promotes the transition to G0 during terminal differentiation in Drosophila. Development. 2015;142:3033-45 pubmed publisher
García Rodríguez L, De Piccoli G, Marchesi V, Jones R, Edmondson R, Labib K. A conserved Polϵ binding module in Ctf18-RFC is required for S-phase checkpoint activation downstream of Mec1. Nucleic Acids Res. 2015;43:8830-8 pubmed publisher
Keller P, Müller C, Engelhardt I, Hiller E, Lemuth K, Eickhoff H, et al. An Antifungal Benzimidazole Derivative Inhibits Ergosterol Biosynthesis and Reveals Novel Sterols. Antimicrob Agents Chemother. 2015;59:6296-307 pubmed publisher
Zebrowski D, Vergarajauregui S, Wu C, Piatkowski T, Becker R, Leone M, et al. Developmental alterations in centrosome integrity contribute to the post-mitotic state of mammalian cardiomyocytes. elife. 2015;4: pubmed publisher
Li Y, Peng L, Seto E. Histone Deacetylase 10 Regulates the Cell Cycle G2/M Phase Transition via a Novel Let-7-HMGA2-Cyclin A2 Pathway. Mol Cell Biol. 2015;35:3547-65 pubmed publisher
Shang Z, Tan W, Liu X, Yu L, Li B, Li M, et al. DNA-PKcs Negatively Regulates Cyclin B1 Protein Stability through Facilitating Its Ubiquitination Mediated by Cdh1-APC/C Pathway. Int J Biol Sci. 2015;11:1026-35 pubmed publisher
Massey A. Multiparametric Cell Cycle Analysis Using the Operetta High-Content Imager and Harmony Software with PhenoLOGIC. PLoS ONE. 2015;10:e0134306 pubmed publisher
Wang S, Lin P, Chiu Y, Huang J, Kuo Y, Wu J, et al. Curcumin-Mediated HDAC Inhibition Suppresses the DNA Damage Response and Contributes to Increased DNA Damage Sensitivity. PLoS ONE. 2015;10:e0134110 pubmed publisher
Chen B, Co C, Ho C. Cell shape dependent regulation of nuclear morphology. Biomaterials. 2015;67:129-36 pubmed publisher
Ben Eliezer I, Pomerantz Y, Galiani D, Nevo N, Dekel N. Appropriate expression of Ube2C and Ube2S controls the progression of the first meiotic division. FASEB J. 2015;29:4670-81 pubmed publisher
Sutani T, Sakata T, Nakato R, Masuda K, Ishibashi M, Yamashita D, et al. Condensin targets and reduces unwound DNA structures associated with transcription in mitotic chromosome condensation. Nat Commun. 2015;6:7815 pubmed publisher
Gurden M, Westwood I, Faisal A, Naud S, Cheung K, McAndrew C, et al. Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. Cancer Res. 2015;75:3340-54 pubmed publisher
Oyama K, Arai T, Isaka A, Sekiguchi T, Itoh H, Seto Y, et al. Directional bleb formation in spherical cells under temperature gradient. Biophys J. 2015;109:355-64 pubmed publisher
Hogan B, Babataheri A, Hwang Y, Barakat A, Husson J. Characterizing cell adhesion by using micropipette aspiration. Biophys J. 2015;109:209-19 pubmed publisher
Sawamura N, Wakabayashi S, Matsumoto K, Yamada H, Asahi T. Cereblon is recruited to aggresome and shows cytoprotective effect against ubiquitin-proteasome system dysfunction. Biochem Biophys Res Commun. 2015;464:1054-1059 pubmed publisher
Ádám C, Fekete A, Bőgel G, Németh Z, Tőkési N, Ovádi J, et al. Accumulation of the PX domain mutant Frank-ter Haar syndrome protein Tks4 in aggresomes. Cell Commun Signal. 2015;13:33 pubmed publisher
Hellewell A, Gong X, Schärich K, Christofidou E, Adams J. Modulation of the extracellular matrix patterning of thrombospondins by actin dynamics and thrombospondin oligomer state. Biosci Rep. 2015;35: pubmed publisher
Madera L, Greenshields A, Coombs M, Hoskin D. 4T1 Murine Mammary Carcinoma Cells Enhance Macrophage-Mediated Innate Inflammatory Responses. PLoS ONE. 2015;10:e0133385 pubmed publisher
Silva R, Dautel M, Di Genova B, Amberg D, Castilho B, Sattlegger E. The Gcn2 Regulator Yih1 Interacts with the Cyclin Dependent Kinase Cdc28 and Promotes Cell Cycle Progression through G2/M in Budding Yeast. PLoS ONE. 2015;10:e0131070 pubmed publisher
Vogan J, Collins K. Dynamics of Human Telomerase Holoenzyme Assembly and Subunit Exchange across the Cell Cycle. J Biol Chem. 2015;290:21320-35 pubmed publisher
Gambarte Tudela J, Capmany A, Romao M, Quintero C, Miserey Lenkei S, Raposo G, et al. The late endocytic Rab39a GTPase regulates the interaction between multivesicular bodies and chlamydial inclusions. J Cell Sci. 2015;128:3068-81 pubmed publisher
Li Villarreal N, Forbes M, Loza A, Chen J, Ma T, Helde K, et al. Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development. 2015;142:2704-18 pubmed publisher
Meyer R, Chuong H, Hild M, Hansen C, Kinter M, Dawson D. Ipl1/Aurora-B is necessary for kinetochore restructuring in meiosis I in Saccharomyces cerevisiae. Mol Biol Cell. 2015;26:2986-3000 pubmed publisher
Lange J, Steinwachs J, Kolb T, Lautscham L, Harder I, Whyte G, et al. Microconstriction arrays for high-throughput quantitative measurements of cell mechanical properties. Biophys J. 2015;109:26-34 pubmed publisher
Stutz C, Reinz E, Honegger A, Bulkescher J, Schweizer J, Zanier K, et al. Intracellular Analysis of the Interaction between the Human Papillomavirus Type 16 E6 Oncoprotein and Inhibitory Peptides. PLoS ONE. 2015;10:e0132339 pubmed publisher
Siriwardana N, Meyer R, Panchenko M. The novel function of JADE1S in cytokinesis of epithelial cells. Cell Cycle. 2015;14:2821-34 pubmed publisher
Gerhardt C, Lier J, Burmühl S, Struchtrup A, Deutschmann K, Vetter M, et al. The transition zone protein Rpgrip1l regulates proteasomal activity at the primary cilium. J Cell Biol. 2015;210:115-33 pubmed publisher
Lim J, Lee K, Woo H, Kang D, Rhee S. Control of the pericentrosomal H2O2 level by peroxiredoxin I is critical for mitotic progression. J Cell Biol. 2015;210:23-33 pubmed publisher
Wu T, Yao Y, Lai I, Lai C, Lin P, Yang W. Loading of PAX3 to Mitotic Chromosomes Is Mediated by Arginine Methylation and Associated with Waardenburg Syndrome. J Biol Chem. 2015;290:20556-64 pubmed publisher
Clift D, Schuh M. A three-step MTOC fragmentation mechanism facilitates bipolar spindle assembly in mouse oocytes. Nat Commun. 2015;6:7217 pubmed publisher
Burgess S, Peset I, Joseph N, Cavazza T, Vernos I, Pfuhl M, et al. Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly. PLoS Genet. 2015;11:e1005345 pubmed publisher
Platani M, Trinkle Mulcahy L, Porter M, Jeyaprakash A, Earnshaw W. Mio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic centrosomes. J Cell Biol. 2015;210:45-62 pubmed publisher
Garcia Belinchón M, Sánchez Osuna M, Martínez Escardó L, Granados Colomina C, Pascual Guiral S, Iglesias Guimarais V, et al. An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death. J Biol Chem. 2015;290:20841-55 pubmed publisher
Reverey J, Jeon J, Bao H, Leippe M, Metzler R, Selhuber Unkel C. Superdiffusion dominates intracellular particle motion in the supercrowded cytoplasm of pathogenic Acanthamoeba castellanii. Sci Rep. 2015;5:11690 pubmed publisher
Goulidaki N, Alarifi S, Alkahtani S, Al Qahtani A, Spandidos D, Stournaras C, et al. RhoB is a component of the human cytomegalovirus assembly complex and is required for efficient viral production. Cell Cycle. 2015;14:2748-63 pubmed publisher
Chou C, Loh J, Yang M, Lin C, Hong M, Cho C, et al. AIBp regulates mitotic entry and mitotic spindle assembly by controlling activation of both Aurora-A and Plk1. Cell Cycle. 2015;14:2764-76 pubmed publisher
Shi X, Yao Y, Wang Y, Zhang Y, Huang Q, Zhou J, et al. Cep70 regulates microtubule stability by interacting with HDAC6. FEBS Lett. 2015;589:1771-7 pubmed publisher
Hernández Varas P, Berge U, Lock J, Stromblad S. A plastic relationship between vinculin-mediated tension and adhesion complex area defines adhesion size and lifetime. Nat Commun. 2015;6:7524 pubmed publisher
Schaeffer E, Vigneron M, Sibler A, Oulad Abdelghani M, Chatton B, Donzeau M. ATF7 is stabilized during mitosis in a CDK1-dependent manner and contributes to cyclin D1 expression. Cell Cycle. 2015;14:2655-66 pubmed publisher
Astanina K, Koch M, Jüngst C, Zumbusch A, Kiemer A. Lipid droplets as a novel cargo of tunnelling nanotubes in endothelial cells. Sci Rep. 2015;5:11453 pubmed publisher
Zhang X, Yan X, Zhang B, Yang Q, Ye M, Cao W, et al. Activity-induced synaptic delivery of the GluN2A-containing NMDA receptor is dependent on endoplasmic reticulum chaperone Bip and involved in fear memory. Cell Res. 2015;25:818-36 pubmed publisher
Whalley H, Porter A, Diamantopoulou Z, White G, Castañeda Saucedo E, Malliri A. Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation. Nat Commun. 2015;6:7437 pubmed publisher
Hoijman E, Rubbini D, Colombelli J, Alsina B. Mitotic cell rounding and epithelial thinning regulate lumen growth and shape. Nat Commun. 2015;6:7355 pubmed publisher
Bílý T, Palus M, Eyer L, Elsterová J, Vancová M, Růžek D. Electron Tomography Analysis of Tick-Borne Encephalitis Virus Infection in Human Neurons. Sci Rep. 2015;5:10745 pubmed publisher
Su X, Wang H, Ge W, Yang M, Hou J, Chen T, et al. An In Vivo Method to Identify microRNA Targets Not Predicted by Computation Algorithms: p21 Targeting by miR-92a in Cancer. Cancer Res. 2015;75:2875-85 pubmed publisher
Negi S, Brown P. rRNA synthesis inhibitor, CX-5461, activates ATM/ATR pathway in acute lymphoblastic leukemia, arrests cells in G2 phase and induces apoptosis. Oncotarget. 2015;6:18094-104 pubmed
Barr A, Bakal C. A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly. Sci Rep. 2015;5:10564 pubmed publisher
Sana T, Baumann C, Merdes A, Soscia C, Rattei T, Hachani A, et al. Internalization of Pseudomonas aeruginosa Strain PAO1 into Epithelial Cells Is Promoted by Interaction of a T6SS Effector with the Microtubule Network. MBio. 2015;6:e00712 pubmed publisher
Serbo J, KUO S, LEWIS S, Lehmann M, Li J, Gracias D, et al. Patterning of Fibroblast and Matrix Anisotropy within 3D Confinement is Driven by the Cytoskeleton. Adv Healthc Mater. 2016;5:146-58 pubmed publisher
Mak J, Man W, Chow J, Ma H, Poon R. Pharmacological inactivation of CHK1 and WEE1 induces mitotic catastrophe in nasopharyngeal carcinoma cells. Oncotarget. 2015;6:21074-84 pubmed
Huang H, Song Y, Wu Y, Guo N, Ma Y, Qian L. Erbin loss promotes cancer cell proliferation through feedback activation of Akt-Skp2-p27 signaling. Biochem Biophys Res Commun. 2015;463:370-6 pubmed publisher
Herms A, Bosch M, Reddy B, Schieber N, Fajardo A, Rupérez C, et al. AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation. Nat Commun. 2015;6:7176 pubmed publisher
Meng L, Park J, Kim T, Lee E, Park S, Zhou M, et al. Bimodal Interaction of Mammalian Polo-Like Kinase 1 and a Centrosomal Scaffold, Cep192, in the Regulation of Bipolar Spindle Formation. Mol Cell Biol. 2015;35:2626-40 pubmed
Schwingshackl A, Roan E, Teng B, Waters C. TREK-1 Regulates Cytokine Secretion from Cultured Human Alveolar Epithelial Cells Independently of Cytoskeletal Rearrangements. PLoS ONE. 2015;10:e0126781 pubmed publisher
Panic M, Hata S, Neuner A, Schiebel E. The centrosomal linker and microtubules provide dual levels of spatial coordination of centrosomes. PLoS Genet. 2015;11:e1005243 pubmed publisher
Egerer J, Emmerich D, Fischer Zirnsak B, Chan W, Meierhofer D, Tuysuz B, et al. GORAB Missense Mutations Disrupt RAB6 and ARF5 Binding and Golgi Targeting. J Invest Dermatol. 2015;135:2368-2376 pubmed publisher
Kloet D, Polderman P, Eijkelenboom A, Smits L, van Triest M, van den Berg M, et al. FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21(Cip1/Waf1). Biochem J. 2015;469:289-98 pubmed publisher
Tong K, Skibbens R. Pds5 regulators segregate cohesion and condensation pathways in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2015;112:7021-6 pubmed publisher
Lillico D, Zwozdesky M, Pemberton J, Deutscher J, Jones L, Chang J, et al. Teleost leukocyte immune-type receptors activate distinct phagocytic modes for target acquisition and engulfment. J Leukoc Biol. 2015;98:235-48 pubmed publisher
Prosser S, Sahota N, Pelletier L, Morrison C, Fry A. Nek5 promotes centrosome integrity in interphase and loss of centrosome cohesion in mitosis. J Cell Biol. 2015;209:339-48 pubmed publisher
Ohira M, Iwasaki Y, Tanaka C, Kuroki M, Matsuo N, Kitamura T, et al. A novel anti-microtubule agent with carbazole and benzohydrazide structures suppresses tumor cell growth in vivo. Biochim Biophys Acta. 2015;1850:1676-84 pubmed publisher
Tholen M, Wolanski J, Stolze B, Chiabudini M, Gajda M, Bronsert P, et al. Stress-resistant Translation of Cathepsin L mRNA in Breast Cancer Progression. J Biol Chem. 2015;290:15758-69 pubmed publisher
Li N, Sun M, Wang Y, Lv Y, Hu Z, Cao W, et al. Effect of cell cycle phase on the sensitivity of SAS cells to sonodynamic therapy using low-intensity ultrasound combined with 5-aminolevulinic acid in vitro. Mol Med Rep. 2015;12:3177-83 pubmed publisher
Cervigni R, Bonavita R, Barretta M, Spano D, Ayala I, Nakamura N, et al. JNK2 controls fragmentation of the Golgi complex and the G2/M transition through phosphorylation of GRASP65. J Cell Sci. 2015;128:2249-60 pubmed publisher
Castelli M, De Pascalis C, Distefano G, Ducano N, Oldani A, Lanzetti L, et al. Regulation of the microtubular cytoskeleton by Polycystin-1 favors focal adhesions turnover to modulate cell adhesion and migration. BMC Cell Biol. 2015;16:15 pubmed publisher
Gerhardt J, Guler G, Fanning E. Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatin. Exp Cell Res. 2015;334:283-93 pubmed publisher
Liu C, Chuang J, Sung C, Mao Y. A dynein independent role of Tctex-1 at the kinetochore. Cell Cycle. 2015;14:1379-88 pubmed publisher
Lian A, Hains P, Sarcevic B, Robinson P, Chircop M. IQGAP1 is associated with nuclear envelope reformation and completion of abscission. Cell Cycle. 2015;14:2058-74 pubmed publisher
Xu H, Dephoure N, Sun H, Zhang H, Fan F, Liu J, et al. Proteomic Profiling of Paclitaxel Treated Cells Identifies a Novel Mechanism of Drug Resistance Mediated by PDCD4. J Proteome Res. 2015;14:2480-91 pubmed publisher
Haschka M, Soratroi C, Kirschnek S, Hacker G, Hilbe R, Geley S, et al. The NOXA-MCL1-BIM axis defines lifespan on extended mitotic arrest. Nat Commun. 2015;6:6891 pubmed publisher
Milev M, Hasaj B, Saint Dic D, Snounou S, Zhao Q, Sacher M. TRAMM/TrappC12 plays a role in chromosome congression, kinetochore stability, and CENP-E recruitment. J Cell Biol. 2015;209:221-34 pubmed publisher
Zhang X, Wang Y. Cell cycle regulation of VCIP135 deubiquitinase activity and function in p97/p47-mediated Golgi reassembly. Mol Biol Cell. 2015;26:2242-51 pubmed publisher
Setyawati M, Tay C, Leong D. Mechanistic Investigation of the Biological Effects of SiO₂, TiO₂, and ZnO Nanoparticles on Intestinal Cells. Small. 2015;11:3458-68 pubmed publisher
Neelam S, Chancellor T, Li Y, Nickerson J, Roux K, Dickinson R, et al. Direct force probe reveals the mechanics of nuclear homeostasis in the mammalian cell. Proc Natl Acad Sci U S A. 2015;112:5720-5 pubmed publisher
Park C, Ryu H, Kim S, Lee D, Song H, Kim K. Presumed pseudokinase VRK3 functions as a BAF kinase. Biochim Biophys Acta. 2015;1853:1738-48 pubmed publisher
Touati S, Buffin E, Cladière D, Hached K, Rachez C, van Deursen J, et al. Mouse oocytes depend on BubR1 for proper chromosome segregation but not for prophase I arrest. Nat Commun. 2015;6:6946 pubmed publisher
Cussiol J, Jablonowski C, Yimit A, Brown G, Smolka M. Dampening DNA damage checkpoint signalling via coordinated BRCT domain interactions. EMBO J. 2015;34:1704-17 pubmed publisher
Piper M, Lee A, van Horck F, McNeilly H, Lu T, Harris W, et al. Differential requirement of F-actin and microtubule cytoskeleton in cue-induced local protein synthesis in axonal growth cones. Neural Dev. 2015;10:3 pubmed publisher
Morra F, Luise C, Merolla F, Poser I, Visconti R, Ilardi G, et al. FBXW7 and USP7 regulate CCDC6 turnover during the cell cycle and affect cancer drugs susceptibility in NSCLC. Oncotarget. 2015;6:12697-709 pubmed
Zhang C, Adalsteinsson V, Francis J, Cornils H, Jung J, Maire C, et al. Calibrating genomic and allelic coverage bias in single-cell sequencing. Nat Commun. 2015;6:6822 pubmed publisher
Li J, Hong M, Chow J, Man W, Mak J, Ma H, et al. Co-inhibition of polo-like kinase 1 and Aurora kinases promotes mitotic catastrophe. Oncotarget. 2015;6:9327-40 pubmed
Bennett G, Peterson C. SWI/SNF recruitment to a DNA double-strand break by the NuA4 and Gcn5 histone acetyltransferases. DNA Repair (Amst). 2015;30:38-45 pubmed publisher
Newman Smith E, Kourakis M, Reeves W, Veeman M, Smith W. Reciprocal and dynamic polarization of planar cell polarity core components and myosin. elife. 2015;4:e05361 pubmed publisher
Linzen U, Lilischkis R, Pandithage R, Schilling B, Ullius A, Lüscher Firzlaff J, et al. ING5 is phosphorylated by CDK2 and controls cell proliferation independently of p53. PLoS ONE. 2015;10:e0123736 pubmed publisher
Gu Q, Yu D, Hu Z, Liu X, Yang Y, Luo Y, et al. miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement. Nat Commun. 2015;6:6789 pubmed publisher
Bekier M, Mazur T, Rashid M, Taylor W. Borealin dimerization mediates optimal CPC checkpoint function by enhancing localization to centromeres and kinetochores. Nat Commun. 2015;6:6775 pubmed publisher
Iacovella M, Golfieri C, Massari L, Busnelli S, Pagliuca C, Dal Maschio M, et al. Rio1 promotes rDNA stability and downregulates RNA polymerase I to ensure rDNA segregation. Nat Commun. 2015;6:6643 pubmed publisher
Mishra P, Guo J, Dittman L, Haase J, Yeh E, Bloom K, et al. Pat1 protects centromere-specific histone H3 variant Cse4 from Psh1-mediated ubiquitination. Mol Biol Cell. 2015;26:2067-79 pubmed publisher
Sulimenko V, Hájková Z, Černohorská M, Sulimenko T, Sládková V, Dráberová L, et al. Microtubule nucleation in mouse bone marrow-derived mast cells is regulated by the concerted action of GIT1/βPIX proteins and calcium. J Immunol. 2015;194:4099-111 pubmed publisher
Revach O, Weiner A, Rechav K, Sabanay I, Livne A, Geiger B. Mechanical interplay between invadopodia and the nucleus in cultured cancer cells. Sci Rep. 2015;5:9466 pubmed publisher
Arulanandam R, Batenchuk C, Varette O, Zakaria C, Garcia V, Forbes N, et al. Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing. Nat Commun. 2015;6:6410 pubmed publisher
Ibrahim R, Lemoine A, Bertoglio J, Raingeaud J. Human enhancer of filamentation 1-induced colorectal cancer cell migration: Role of serine phosphorylation and interaction with the breast cancer anti-estrogen resistance 3 protein. Int J Biochem Cell Biol. 2015;64:45-57 pubmed publisher
Wales C, Taylor F, Higa A, McAllister H, Jacobs A. ERK-dependent phosphorylation of HSF1 mediates chemotherapeutic resistance to benzimidazole carbamates in colorectal cancer cells. Anticancer Drugs. 2015;26:657-66 pubmed publisher
Davies C, Brown C, Westphal D, Ward J, Ward V. Murine norovirus replication induces G0/G1 cell cycle arrest in asynchronously growing cells. J Virol. 2015;89:6057-66 pubmed publisher
Ahmad T, Sundar I, Lerner C, Gerloff J, Tormos A, Yao H, et al. Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease. FASEB J. 2015;29:2912-29 pubmed publisher
Chen D, Ito S, Yuan H, Hyodo T, Kadomatsu K, Hamaguchi M, et al. EML4 promotes the loading of NUDC to the spindle for mitotic progression. Cell Cycle. 2015;14:1529-39 pubmed publisher
Okamoto A, Yabuta N, Mukai S, Torigata K, Nojima H. Phosphorylation of CHO1 by Lats1/2 regulates the centrosomal activation of LIMK1 during cytokinesis. Cell Cycle. 2015;14:1568-82 pubmed publisher
Stellas D, Souliotis V, Bekyrou M, Smirlis D, Kirsch Volders M, Degrassi F, et al. Benzo[a]pyrene-induced cell cycle arrest in HepG2 cells is associated with delayed induction of mitotic instability. Mutat Res. 2014;769:59-68 pubmed publisher
Gustafsson A, Abramenkovs A, Stenerlöw B. Suppression of DNA-dependent protein kinase sensitize cells to radiation without affecting DSB repair. Mutat Res. 2014;769:1-10 pubmed publisher
Storti B, Di Rienzo C, Cardarelli F, Bizzarri R, Beltram F. Unveiling TRPV1 spatio-temporal organization in live cell membranes. PLoS ONE. 2015;10:e0116900 pubmed publisher
Teixeira J, Silva P, Faria J, Ferreira I, Duarte P, Delgado M, et al. Clinicopathologic significance of BubR1 and Mad2 overexpression in oral cancer. Oral Dis. 2015;21:713-20 pubmed publisher
Garcez P, Díaz Alonso J, Crespo Enríquez I, Castro D, Bell D, Guillemot F. Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1. Nat Commun. 2015;6:6474 pubmed publisher
Blom M, Reis K, Nehru V, Blom H, Gad A, Aspenström P. RhoD is a Golgi component with a role in anterograde protein transport from the ER to the plasma membrane. Exp Cell Res. 2015;333:208-19 pubmed publisher
Berruti G, Paiardi C. USP8/UBPy-regulated sorting and the development of sperm acrosome: the recruitment of MET. Reproduction. 2015;149:633-44 pubmed publisher
Visconti R, Della Monica R, Palazzo L, D Alessio F, Raia M, Improta S, et al. The Fcp1-Wee1-Cdk1 axis affects spindle assembly checkpoint robustness and sensitivity to antimicrotubule cancer drugs. Cell Death Differ. 2015;22:1551-60 pubmed publisher
Hiyoshi H, Okada R, Matsuda S, Gotoh K, Akeda Y, Iida T, et al. Interaction between the type III effector VopO and GEF-H1 activates the RhoA-ROCK pathway. PLoS Pathog. 2015;11:e1004694 pubmed publisher
Kim J, Gil N, Zhang X, Chun K, Fang G, Kim J, et al. Sirt1 Regulates Microtubule Dynamics Through Negative Regulation of Plk1 in Mitosis. J Cell Biochem. 2015;116:1888-97 pubmed publisher
She T, Qu L, Wang L, Yang X, Xu S, Feng J, et al. Sarsaparilla (Smilax Glabra Rhizome) Extract Inhibits Cancer Cell Growth by S Phase Arrest, Apoptosis, and Autophagy via Redox-Dependent ERK1/2 Pathway. Cancer Prev Res (Phila). 2015;8:464-74 pubmed publisher
Valakh V, Frey E, Babetto E, Walker L, DiAntonio A. Cytoskeletal disruption activates the DLK/JNK pathway, which promotes axonal regeneration and mimics a preconditioning injury. Neurobiol Dis. 2015;77:13-25 pubmed publisher
Masuda K, Chiyoda T, Sugiyama N, Segura Cabrera A, Kabe Y, Ueki A, et al. LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C. PLoS ONE. 2015;10:e0118662 pubmed publisher
Rondinelli B, Schwerer H, Antonini E, Gaviraghi M, Lupi A, Frenquelli M, et al. H3K4me3 demethylation by the histone demethylase KDM5C/JARID1C promotes DNA replication origin firing. Nucleic Acids Res. 2015;43:2560-74 pubmed publisher
Matsuoka K, Iimori M, Niimi S, Tsukihara H, Watanabe S, Kiyonari S, et al. Trifluridine Induces p53-Dependent Sustained G2 Phase Arrest with Its Massive Misincorporation into DNA and Few DNA Strand Breaks. Mol Cancer Ther. 2015;14:1004-13 pubmed publisher
Mäki Jouppila J, Pruikkonen S, Tambe M, Aure M, Halonen T, Salmela A, et al. MicroRNA let-7b regulates genomic balance by targeting Aurora B kinase. Mol Oncol. 2015;9:1056-70 pubmed publisher
Ishihara S, Yasuda M, Ishizu A, Ishikawa M, Shirato H, Haga H. Activating transcription factor 5 enhances radioresistance and malignancy in cancer cells. Oncotarget. 2015;6:4602-14 pubmed
Kandel J, Chou P, Eckmann D. Automated detection of whole-cell mitochondrial motility and its dependence on cytoarchitectural integrity. Biotechnol Bioeng. 2015;112:1395-405 pubmed publisher
Goldmacher V, Audette C, Guan Y, Sidhom E, Shah J, Whiteman K, et al. High-affinity accumulation of a maytansinoid in cells via weak tubulin interaction. PLoS ONE. 2015;10:e0117523 pubmed publisher
Kim T, Joo C, Seong J, Vafabakhsh R, Botvinick E, Berns M, et al. Distinct mechanisms regulating mechanical force-induced Ca²? signals at the plasma membrane and the ER in human MSCs. elife. 2015;4:e04876 pubmed publisher
Kanginakudru S, Desmet M, Thomas Y, Morgan I, Androphy E. Levels of the E2 interacting protein TopBP1 modulate papillomavirus maintenance stage replication. Virology. 2015;478:129-35 pubmed publisher
Jeong H, Gil N, Lee H, Cho S, Kim K, Chun K, et al. Timely Degradation of Wip1 Phosphatase by APC/C Activator Protein Cdh1 is Necessary for Normal Mitotic Progression. J Cell Biochem. 2015;116:1602-12 pubmed publisher
Huang Y, Chang S, Harn H, Huang H, Lin H, Shen M, et al. Mechanosensitive store-operated calcium entry regulates the formation of cell polarity. J Cell Physiol. 2015;230:2086-97 pubmed publisher
Horibe S, Matsuda A, Tanahashi T, Inoue J, Kawauchi S, Mizuno S, et al. Cisplatin resistance in human lung cancer cells is linked with dysregulation of cell cycle associated proteins. Life Sci. 2015;124:31-40 pubmed publisher
Byron A, Askari J, Humphries J, Jacquemet G, Koper E, Warwood S, et al. A proteomic approach reveals integrin activation state-dependent control of microtubule cortical targeting. Nat Commun. 2015;6:6135 pubmed publisher
Wang K, Yan R, Cooper K, Strich R. Cyclin C mediates stress-induced mitochondrial fission and apoptosis. Mol Biol Cell. 2015;26:1030-43 pubmed publisher
Vosper J, Masuccio A, Kullmann M, Ploner C, Geley S, Hengst L. Statin-induced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation. Oncotarget. 2015;6:2889-902 pubmed
Hyun S, Jang Y. p53 activates G₁ checkpoint following DNA damage by doxorubicin during transient mitotic arrest. Oncotarget. 2015;6:4804-15 pubmed
Kim S, Yu H. Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at human mitotic kinetochores. J Cell Biol. 2015;208:181-96 pubmed publisher
Attia S, Ahmad S, Okash R, Bakheet S. Dominant lethal effects of nocodazole in germ cells of male mice. Food Chem Toxicol. 2015;77:101-4 pubmed publisher
Stolz A, Ertych N, Bastians H. A phenotypic screen identifies microtubule plus end assembly regulators that can function in mitotic spindle orientation. Cell Cycle. 2015;14:827-37 pubmed publisher
Rizkallah R, Batsomboon P, Dudley G, Hurt M. Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins. Oncotarget. 2015;6:1446-61 pubmed
Moszczynski A, Gohar M, Volkening K, Leystra Lantz C, Strong W, Strong M. Thr175-phosphorylated tau induces pathologic fibril formation via GSK3β-mediated phosphorylation of Thr231 in vitro. Neurobiol Aging. 2015;36:1590-9 pubmed publisher
Valianou M, Cox A, Pichette B, Hartley S, Paladhi U, Astrinidis A. Pharmacological inhibition of Polo-like kinase 1 (PLK1) by BI-2536 decreases the viability and survival of hamartin and tuberin deficient cells via induction of apoptosis and attenuation of autophagy. Cell Cycle. 2015;14:399-407 pubmed publisher
Klein D, Hoffmann S, Ahlskog J, O Hanlon K, Quaas M, Larsen B, et al. Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control. Nat Commun. 2015;6:5800 pubmed publisher
Song H, Pan J, Liu Y, Wen H, Wang L, Cui J, et al. Increased ARPP-19 expression is associated with hepatocellular carcinoma. Int J Mol Sci. 2014;16:178-92 pubmed publisher
Chae H, Mitton B, Lacayo N, Sakamoto K. Replication factor C3 is a CREB target gene that regulates cell cycle progression through the modulation of chromatin loading of PCNA. Leukemia. 2015;29:1379-89 pubmed publisher
Cao J, Lin C, Wang H, Wang L, Zhou N, Jin Y, et al. Circovirus transport proceeds via direct interaction of the cytoplasmic dynein IC1 subunit with the viral capsid protein. J Virol. 2015;89:2777-91 pubmed publisher
Zhong G, He J, Zhou R, LORENZO D, Babcock H, Bennett V, et al. Developmental mechanism of the periodic membrane skeleton in axons. elife. 2014;3: pubmed publisher
Zheng H, Tang C, Yin C. Exploring advantages/disadvantages and improvements in overcoming gene delivery barriers of amino acid modified trimethylated chitosan. Pharm Res. 2015;32:2038-50 pubmed publisher
Zhang W, Liu Y, Zhao N, Chen H, Qiao L, Zhao W, et al. Role of Cdk1 in the p53-independent abrogation of the postmitotic checkpoint by human papillomavirus E6. J Virol. 2015;89:2553-62 pubmed publisher
Hui K, Balagopalan L, Samelson L, Upadhyaya A. Cytoskeletal forces during signaling activation in Jurkat T-cells. Mol Biol Cell. 2015;26:685-95 pubmed publisher
Osman A, Monroe M, Ortega Alves M, Patel A, Katsonis P, Fitzgerald A, et al. Wee-1 kinase inhibition overcomes cisplatin resistance associated with high-risk TP53 mutations in head and neck cancer through mitotic arrest followed by senescence. Mol Cancer Ther. 2015;14:608-19 pubmed publisher
Pawlica P, Dufour C, Berthoux L. Inhibition of microtubules and dynein rescues human immunodeficiency virus type 1 from owl monkey TRIMCyp-mediated restriction in a cellular context-specific fashion. J Gen Virol. 2015;96:874-86 pubmed publisher
Maskey R, Kim M, Baker D, Childs B, Malureanu L, Jeganathan K, et al. Spartan deficiency causes genomic instability and progeroid phenotypes. Nat Commun. 2014;5:5744 pubmed publisher
Carey S, Rahman A, Kraning Rush C, Romero B, Somasegar S, Torre O, et al. Comparative mechanisms of cancer cell migration through 3D matrix and physiological microtracks. Am J Physiol Cell Physiol. 2015;308:C436-47 pubmed publisher
Lin S, Staahl B, Alla R, Doudna J. Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery. elife. 2014;3:e04766 pubmed publisher
Xue L, Furusawa Y, Okayasu R, Miura M, Cui X, Liu C, et al. The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function. DNA Repair (Amst). 2015;25:72-83 pubmed publisher
Li C, Yang J, Lin D, Zhao Y, Liu S, Xing S, et al. Phosphorylation of ribosomal protein S6 kinase 1 at Thr421/Ser424 and dephosphorylation at Thr389 regulates SP600125-induced polyploidization of megakaryocytic cell lines. PLoS ONE. 2014;9:e114389 pubmed publisher
Kim H, Guo F, Brahma S, Xing Y, Burkard M. Centralspindlin assembly and 2 phosphorylations on MgcRacGAP by Polo-like kinase 1 initiate Ect2 binding in early cytokinesis. Cell Cycle. 2014;13:2952-61 pubmed publisher
Asano E, Hasegawa H, Hyodo T, Ito S, Maeda M, Chen D, et al. SHCBP1 is required for midbody organization and cytokinesis completion. Cell Cycle. 2014;13:2744-51 pubmed publisher
Müllers E, Silva Cascales H, Jaiswal H, Saurin A, Lindqvist A. Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase. Cell Cycle. 2014;13:2733-43 pubmed publisher
Vandame P, Spriet C, Trinel D, Gelaude A, Caillau K, Bompard C, et al. The spatio-temporal dynamics of PKA activity profile during mitosis and its correlation to chromosome segregation. Cell Cycle. 2014;13:3232-40 pubmed publisher
Han D, Na H, Choi W, Lee J, Kim Y, Won C, et al. Direct cellular delivery of human proteasomes to delay tau aggregation. Nat Commun. 2014;5:5633 pubmed publisher
Hsu C, Pan Y, Liu J, Chen C, Lin T, Wang J. Klebsiella pneumoniae translocates across the intestinal epithelium via Rho GTPase- and phosphatidylinositol 3-kinase/Akt-dependent cell invasion. Infect Immun. 2015;83:769-79 pubmed publisher
Roberts K, Manicassamy B, Lamb R. Influenza A virus uses intercellular connections to spread to neighboring cells. J Virol. 2015;89:1537-49 pubmed publisher
Kim H, Kim S, Pyun H, Maeng J, Lee K. Cellular uptake mechanism of TCTP-PTD in human lung carcinoma cells. Mol Pharm. 2015;12:194-203 pubmed publisher
Li H, Zhong X, Chau K, Santistevan N, Guo W, Kong G, et al. Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesis involving the Notch signalling pathway. Nat Commun. 2014;5:5601 pubmed publisher
Wu Y, Zhuo X, Dai Z, Guo X, Wang Y, Zhang C, et al. Modeling the mitotic regulatory network identifies highly efficient anti-cancer drug combinations. Mol Biosyst. 2015;11:497-505 pubmed publisher
Bender M, Thon J, Ehrlicher A, Wu S, Mazutis L, Deschmann E, et al. Microtubule sliding drives proplatelet elongation and is dependent on cytoplasmic dynein. Blood. 2015;125:860-8 pubmed publisher
Jin H, Dai S, Song W, Yao G, Shi S, Sun Y. Embryo developmental potential of microsurgically corrected human three-pronuclear zygotes. Syst Biol Reprod Med. 2015;61:96-102 pubmed publisher
Nijenhuis W, Vallardi G, Teixeira A, Kops G, Saurin A. Negative feedback at kinetochores underlies a responsive spindle checkpoint signal. Nat Cell Biol. 2014;16:1257-64 pubmed publisher
Latham A, Kankanala J, Fearnley G, Gage M, Kearney M, Homer Vanniasinkam S, et al. In silico design and biological evaluation of a dual specificity kinase inhibitor targeting cell cycle progression and angiogenesis. PLoS ONE. 2014;9:e110997 pubmed publisher
Guacci V, Stricklin J, Bloom M, Guō X, Bhatter M, Koshland D. A novel mechanism for the establishment of sister chromatid cohesion by the ECO1 acetyltransferase. Mol Biol Cell. 2015;26:117-33 pubmed publisher
Burkard C, Verheije M, Wicht O, van Kasteren S, van Kuppeveld F, Haagmans B, et al. Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner. PLoS Pathog. 2014;10:e1004502 pubmed publisher
Yamaguchi S, Maida Y, Yasukawa M, Kato T, Yoshida M, Masutomi K. Eribulin mesylate targets human telomerase reverse transcriptase in ovarian cancer cells. PLoS ONE. 2014;9:e112438 pubmed publisher
Juan G, Bush T, Ma C, Manoukian R, Chung G, Hawkins J, et al. AMG 900, a potent inhibitor of aurora kinases causes pharmacodynamic changes in p-Histone H3 immunoreactivity in human tumor xenografts and proliferating mouse tissues. J Transl Med. 2014;12:307 pubmed publisher
Greve K, Lindgreen J, Terp M, Pedersen C, Schmidt S, Mollenhauer J, et al. Ectopic expression of cancer/testis antigen SSX2 induces DNA damage and promotes genomic instability. Mol Oncol. 2015;9:437-49 pubmed publisher
Choi B, Chattopadhaya S, Thanh L, Feng L, Nguyen Q, Lim C, et al. Suprafenacine, an indazole-hydrazide agent, targets cancer cells through microtubule destabilization. PLoS ONE. 2014;9:e110955 pubmed publisher
Samba Louaka A, Pereira J, Nahori M, Villiers V, Deriano L, Hamon M, et al. Listeria monocytogenes dampens the DNA damage response. PLoS Pathog. 2014;10:e1004470 pubmed publisher
Decembre E, Assil S, Hillaire M, Dejnirattisai W, Mongkolsapaya J, Screaton G, et al. Sensing of immature particles produced by dengue virus infected cells induces an antiviral response by plasmacytoid dendritic cells. PLoS Pathog. 2014;10:e1004434 pubmed publisher
Jeppsson K, Carlborg K, Nakato R, Berta D, Lilienthal I, Kanno T, et al. The chromosomal association of the Smc5/6 complex depends on cohesion and predicts the level of sister chromatid entanglement. PLoS Genet. 2014;10:e1004680 pubmed publisher
Bannunah A, Vllasaliu D, Lord J, Stolnik S. Mechanisms of nanoparticle internalization and transport across an intestinal epithelial cell model: effect of size and surface charge. Mol Pharm. 2014;11:4363-73 pubmed publisher
Valignat M, Nègre P, Cadra S, Lellouch A, Gallet F, Hénon S, et al. Lymphocytes can self-steer passively with wind vane uropods. Nat Commun. 2014;5:5213 pubmed publisher
Wang W, Pan G, Zhang Z, Suo Z, Yang X, Hu X. Ht31 peptide inhibited inflammatory pain by blocking NMDA receptor-mediated nociceptive transmission in spinal dorsal horn of mice. Neuropharmacology. 2015;89:290-7 pubmed publisher
Heaslip A, Nelson S, Lombardo A, Beck Previs S, Armstrong J, Warshaw D. Cytoskeletal dependence of insulin granule movement dynamics in INS-1 beta-cells in response to glucose. PLoS ONE. 2014;9:e109082 pubmed publisher
Tian Y, Wu M, Liu X, Liu Z, Zhou Q, Niu Z, et al. Probing the endocytic pathways of the filamentous bacteriophage in live cells using ratiometric pH fluorescent indicator. Adv Healthc Mater. 2015;4:413-9 pubmed publisher
Franciszkiewicz K, Boutet M, Gauthier L, Vergnon I, Peeters K, Duc O, et al. Synaptic release of CCL5 storage vesicles triggers CXCR4 surface expression promoting CTL migration in response to CXCL12. J Immunol. 2014;193:4952-61 pubmed publisher
Felix C, Kaplan Türköz B, Ranaldi S, Koelblen T, Terradot L, O Callaghan D, et al. The Brucella TIR domain containing proteins BtpA and BtpB have a structural WxxxE motif important for protection against microtubule depolymerisation. Cell Commun Signal. 2014;12:53 pubmed publisher
Mak J, Man W, Ma H, Poon R. Pharmacological targeting the ATR-CHK1-WEE1 axis involves balancing cell growth stimulation and apoptosis. Oncotarget. 2014;5:10546-57 pubmed
Volceanov L, Herbst K, Biniossek M, Schilling O, Haller D, Nölke T, et al. Septins arrange F-actin-containing fibers on the Chlamydia trachomatis inclusion and are required for normal release of the inclusion by extrusion. MBio. 2014;5:e01802-14 pubmed publisher
Anitei M, Chenna R, Czupalla C, Esner M, Christ S, Lenhard S, et al. A high-throughput siRNA screen identifies genes that regulate mannose 6-phosphate receptor trafficking. J Cell Sci. 2014;127:5079-92 pubmed publisher
Waraky A, Akopyan K, Parrow V, Strömberg T, Axelson M, Abrahmsén L, et al. Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via insulin-like growth factor-1 receptor-independent mechanism. Oncotarget. 2014;5:8379-92 pubmed
Sundaramoorthy S, Vázquez Novelle M, Lekomtsev S, Howell M, Petronczki M. Functional genomics identifies a requirement of pre-mRNA splicing factors for sister chromatid cohesion. EMBO J. 2014;33:2623-42 pubmed publisher
Zhang Z, Hou X, Shao C, Li J, Cheng J, Kuang S, et al. Plk1 inhibition enhances the efficacy of androgen signaling blockade in castration-resistant prostate cancer. Cancer Res. 2014;74:6635-47 pubmed publisher
Iwashita M, Kataoka N, Toida K, Kosodo Y. Systematic profiling of spatiotemporal tissue and cellular stiffness in the developing brain. Development. 2014;141:3793-8 pubmed publisher
Poliakova K, Adebola A, Leung C, Favre B, Liem R, Schepens I, et al. BPAG1a and b associate with EB1 and EB3 and modulate vesicular transport, Golgi apparatus structure, and cell migration in C2.7 myoblasts. PLoS ONE. 2014;9:e107535 pubmed publisher
Zhen C, Duc H, Kokotovic M, Phiel C, Ren X. Cbx2 stably associates with mitotic chromosomes via a PRC2- or PRC1-independent mechanism and is needed for recruiting PRC1 complex to mitotic chromosomes. Mol Biol Cell. 2014;25:3726-39 pubmed publisher
Lukic Z, Dharan A, Fricke T, Diaz Griffero F, Campbell E. HIV-1 uncoating is facilitated by dynein and kinesin 1. J Virol. 2014;88:13613-25 pubmed publisher
Roland A, Ricobaraza A, Carrel D, Jordan B, Rico F, Simon A, et al. Cannabinoid-induced actomyosin contractility shapes neuronal morphology and growth. elife. 2014;3:e03159 pubmed publisher
Smith S, Petrova A, Madden M, Wang H, Pan Y, Warren M, et al. A gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress response. Nucleic Acids Res. 2014;42:11517-27 pubmed publisher
Devadas D, Koithan T, Diestel R, Prank U, Sodeik B, Döhner K. Herpes simplex virus internalization into epithelial cells requires Na+/H+ exchangers and p21-activated kinases but neither clathrin- nor caveolin-mediated endocytosis. J Virol. 2014;88:13378-95 pubmed publisher
Gold W, Lacina T, Cantrill L, Christodoulou J. MeCP2 deficiency is associated with reduced levels of tubulin acetylation and can be restored using HDAC6 inhibitors. J Mol Med (Berl). 2015;93:63-72 pubmed publisher
Nath S, Munsie L, Truant R. A huntingtin-mediated fast stress response halting endosomal trafficking is defective in Huntington's disease. Hum Mol Genet. 2015;24:450-62 pubmed publisher
Foijer F, Xie S, Simon J, Bakker P, Conte N, Davis S, et al. Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress. Proc Natl Acad Sci U S A. 2014;111:13427-32 pubmed publisher
Raab M, Krämer A, Hehlgans S, Sanhaji M, Kurunci Csacsko E, Dötsch C, et al. Mitotic arrest and slippage induced by pharmacological inhibition of Polo-like kinase 1. Mol Oncol. 2015;9:140-54 pubmed publisher
Terasawa M, Shinohara A, Shinohara M. Canonical non-homologous end joining in mitosis induces genome instability and is suppressed by M-phase-specific phosphorylation of XRCC4. PLoS Genet. 2014;10:e1004563 pubmed publisher
Wang S, Huang X, Huang Y, Hao X, Xu H, Cai M, et al. Entry of a novel marine DNA virus, Singapore grouper iridovirus, into host cells occurs via clathrin-mediated endocytosis and macropinocytosis in a pH-dependent manner. J Virol. 2014;88:13047-63 pubmed publisher
Stauffer S, Feng Y, Nebioglu F, Heilig R, Picotti P, Helenius A. Stepwise priming by acidic pH and a high K+ concentration is required for efficient uncoating of influenza A virus cores after penetration. J Virol. 2014;88:13029-46 pubmed publisher
Yoshimi A, Toya T, Kawazu M, Ueno T, Tsukamoto A, Iizuka H, et al. Recurrent CDC25C mutations drive malignant transformation in FPD/AML. Nat Commun. 2014;5:4770 pubmed publisher
Asteriti I, Di Cesare E, De Mattia F, Hilsenstein V, Neumann B, Cundari E, et al. The Aurora-A inhibitor MLN8237 affects multiple mitotic processes and induces dose-dependent mitotic abnormalities and aneuploidy. Oncotarget. 2014;5:6229-42 pubmed
Maudet C, Mano M, Sunkavalli U, Sharan M, Giacca M, Förstner K, et al. Functional high-throughput screening identifies the miR-15 microRNA family as cellular restriction factors for Salmonella infection. Nat Commun. 2014;5:4718 pubmed publisher
Mudhasani R, Kota K, Retterer C, Tran J, Whitehouse C, Bavari S. High content image-based screening of a protease inhibitor library reveals compounds broadly active against Rift Valley fever virus and other highly pathogenic RNA viruses. PLoS Negl Trop Dis. 2014;8:e3095 pubmed publisher
Qin Q, Cheng H, Lu J, Zhan L, Zheng J, Cai J, et al. Small-molecule survivin inhibitor YM155 enhances radiosensitization in esophageal squamous cell carcinoma by the abrogation of G2 checkpoint and suppression of homologous recombination repair. J Hematol Oncol. 2014;7:62 pubmed publisher
Gustafsson J, Linden S, Alwan A, Scholte B, Hansson G, Sjovall H. Carbachol-induced colonic mucus formation requires transport via NKCC1, K⁺ channels and CFTR. Pflugers Arch. 2015;467:1403-1415 pubmed publisher
Pedrazzi M, Nash B, Meucci O, Brandimarti R. Molecular features contributing to virus-independent intracellular localization and dynamic behavior of the herpesvirus transport protein US9. PLoS ONE. 2014;9:e104634 pubmed publisher
Lee J, Lee D. Leucine methylation of protein phosphatase PP4C at C-terminal is critical for its cellular functions. Biochem Biophys Res Commun. 2014;452:42-7 pubmed publisher
Higginbotham K, Tian Y, Gawlak G, Moldobaeva N, Shah A, Birukova A. Hepatocyte growth factor triggers distinct mechanisms of Asef and Tiam1 activation to induce endothelial barrier enhancement. Cell Signal. 2014;26:2306-16 pubmed publisher
Ritchey L, Chakrabarti R. Aurora A kinase modulates actin cytoskeleton through phosphorylation of Cofilin: Implication in the mitotic process. Biochim Biophys Acta. 2014;1843:2719-29 pubmed publisher
Boudreau L, Duchez A, Cloutier N, Soulet D, Martin N, Bollinger J, et al. Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation. Blood. 2014;124:2173-83 pubmed publisher
Wiens O, Xia D, von Schubert C, Wastling J, Dobbelaere D, Heussler V, et al. Cell cycle-dependent phosphorylation of Theileria annulata schizont surface proteins. PLoS ONE. 2014;9:e103821 pubmed publisher
Felipe K, Kviecinski M, da Silva F, Bücker N, Farias M, Castro L, et al. Inhibition of tumor proliferation associated with cell cycle arrest caused by extract and fraction from Casearia sylvestris (Salicaceae). J Ethnopharmacol. 2014;155:1492-9 pubmed publisher
Kleyman M, Kabeche L, Compton D. STAG2 promotes error correction in mitosis by regulating kinetochore-microtubule attachments. J Cell Sci. 2014;127:4225-33 pubmed publisher
Halley Stott R, Jullien J, Pasque V, Gurdon J. Mitosis gives a brief window of opportunity for a change in gene transcription. PLoS Biol. 2014;12:e1001914 pubmed publisher
Du S, Wang H, Cheng H, Chen S, Wang L, Wang W. Cholesterol glucosylation by Helicobacter pylori delays internalization and arrests phagosome maturation in macrophages. J Microbiol Immunol Infect. 2016;49:636-645 pubmed publisher
Silva P, Reis R, Bolanos Garcia V, Florindo C, Tavares A, Bousbaa H. Dynein-dependent transport of spindle assembly checkpoint proteins off kinetochores toward spindle poles. FEBS Lett. 2014;588:3265-73 pubmed publisher
Chiotaki R, Polioudaki H, Theodoropoulos P. Differential nuclear shape dynamics of invasive andnon-invasive breast cancer cells are associated with actin cytoskeleton organization and stability. Biochem Cell Biol. 2014;92:287-95 pubmed publisher
Laufer R, Ng G, Liu Y, Patel N, Edwards L, Lang Y, et al. Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides. Bioorg Med Chem. 2014;22:4968-97 pubmed publisher
Guerrero P, Yin W, Camacho L, Marchetti D. Oncogenic role of Merlin/NF2 in glioblastoma. Oncogene. 2015;34:2621-30 pubmed publisher
Hirata A, Nokihara K, Kawamoto Y, Bando T, Sasaki A, Ide S, et al. Structural evaluation of tandem hairpin pyrrole-imidazole polyamides recognizing human telomeres. J Am Chem Soc. 2014;136:11546-54 pubmed publisher
Bun P, Liu J, Turlier H, Liu Z, Uriot K, Joanny J, et al. Mechanical checkpoint for persistent cell polarization in adhesion-naive fibroblasts. Biophys J. 2014;107:324-335 pubmed publisher
Kamthan M, Nalla V, Ruhela D, Kamthan A, Maiti P, Datta A. Characterization of a putative spindle assembly checkpoint kinase Mps1, suggests its involvement in cell division, morphogenesis and oxidative stress tolerance in Candida albicans. PLoS ONE. 2014;9:e101517 pubmed publisher
Diaz Martinez L, Karamysheva Z, Warrington R, Li B, Wei S, Xie X, et al. Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation. EMBO J. 2014;33:1960-76 pubmed publisher
Saito K, Iizuka Y, Ohta S, Takahashi S, Nakamura K, Saya H, et al. Functional analysis of a novel glioma antigen, EFTUD1. Neuro Oncol. 2014;16:1618-29 pubmed publisher
Chiu S, Chen J, Wei T, Cheng T, Wang Y, Ku C, et al. The mitosis-regulating and protein-protein interaction activities of astrin are controlled by aurora-A-induced phosphorylation. Am J Physiol Cell Physiol. 2014;307:C466-78 pubmed publisher
Sau S, Sutradhar S, Paul R, Sinha P. Budding yeast kinetochore proteins, Chl4 and Ctf19, are required to maintain SPB-centromere proximity during G1 and late anaphase. PLoS ONE. 2014;9:e101294 pubmed publisher
Melemedjian O, Tillu D, Moy J, Asiedu M, Mandell E, Ghosh S, et al. Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity. Mol Pain. 2014;10:45 pubmed publisher
Remez L, Zobor D, Kohl S, Ben Yosef T. The progressive rod-cone degeneration (PRCD) protein is secreted through the conventional ER/Golgi-dependent pathway. Exp Eye Res. 2014;125:217-25 pubmed publisher
Meshkibaf S, Gower M, Dekaban G, Kim S. G-CSF preferentially supports the generation of gut-homing Gr-1high macrophages in M-CSF-treated bone marrow cells. J Leukoc Biol. 2014;96:549-61 pubmed publisher
Wong M, Byun J, Sacta M, Jin Q, Baek S, Gardner K. Promoter-bound p300 complexes facilitate post-mitotic transmission of transcriptional memory. PLoS ONE. 2014;9:e99989 pubmed publisher
Yang H, Lawrence H, Kazi A, Gevariya H, Patel R, Luo Y, et al. Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation. Oncotarget. 2014;5:2947-61 pubmed
Glotfelty L, Zahs A, Iancu C, Shen L, Hecht G. Microtubules are required for efficient epithelial tight junction homeostasis and restoration. Am J Physiol Cell Physiol. 2014;307:C245-54 pubmed publisher
Xu R, Xiong B, Zhou R, Shen H, Yeung E, He Y. Pericellular matrix plays an active role in retention and cellular uptake of large-sized nanoparticles. Anal Bioanal Chem. 2014;406:5031-7 pubmed publisher
Lai C, Saxena V, Tseng C, Jeng K, Kohara M, Lai M. Nonstructural protein 5A is incorporated into hepatitis C virus low-density particle through interaction with core protein and microtubules during intracellular transport. PLoS ONE. 2014;9:e99022 pubmed publisher
Yeh C, Yen C, Chen Y, Cheng C, Huang S, Chang T, et al. Identification of aurora kinase A as an unfavorable prognostic factor and potential treatment target for metastatic gastrointestinal stromal tumors. Oncotarget. 2014;5:4071-86 pubmed
Lyi S, Tan M, Parrish C. Parvovirus particles and movement in the cellular cytoplasm and effects of the cytoskeleton. Virology. 2014;456-457:342-52 pubmed publisher
Hirokawa T, Shiotani B, Shimada M, Murata K, Johmura Y, Haruta M, et al. CBP-93872 inhibits NBS1-mediated ATR activation, abrogating maintenance of the DNA double-strand break-specific G2 checkpoint. Cancer Res. 2014;74:3880-9 pubmed publisher
Chen H, Mohan P, Jiang J, Nemirovsky O, He D, Fleisch M, et al. Spatial regulation of Aurora A activity during mitotic spindle assembly requires RHAMM to correctly localize TPX2. Cell Cycle. 2014;13:2248-61 pubmed publisher
Lodhi N, Kossenkov A, Tulin A. Bookmarking promoters in mitotic chromatin: poly(ADP-ribose)polymerase-1 as an epigenetic mark. Nucleic Acids Res. 2014;42:7028-38 pubmed publisher
Sinnott R, Winters L, Larson B, Mytsa D, Taus P, Cappell K, et al. Mechanisms promoting escape from mitotic stress-induced tumor cell death. Cancer Res. 2014;74:3857-69 pubmed publisher
Stehbens S, Paszek M, Pemble H, Ettinger A, Gierke S, Wittmann T. CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover. Nat Cell Biol. 2014;16:561-73 pubmed publisher
Ma J, Wu L, Hou Z, Song Y, Wang L, Jiang W. Visualizing the endocytosis of phenylephrine in living cells by quantum dot-based tracking. Biomaterials. 2014;35:7042-9 pubmed publisher
Siddique R, Vyas A, Thakor N, Brushart T. A two-compartment organotypic model of mammalian peripheral nerve repair. J Neurosci Methods. 2014;232:84-92 pubmed publisher
Zila V, Difato F, Klimova L, Huerfano S, Forstova J. Involvement of microtubular network and its motors in productive endocytic trafficking of mouse polyomavirus. PLoS ONE. 2014;9:e96922 pubmed publisher
Bertrand A, Ziaei S, Ehret C, Duchemin H, Mamchaoui K, Bigot A, et al. Cellular microenvironments reveal defective mechanosensing responses and elevated YAP signaling in LMNA-mutated muscle precursors. J Cell Sci. 2014;127:2873-84 pubmed publisher
Shigetomi H, Sudo T, Shimada K, Uekuri C, Tsuji Y, Kanayama S, et al. Inhibition of cell death and induction of G2 arrest accumulation in human ovarian clear cells by HNF-1β transcription factor: chemosensitivity is regulated by checkpoint kinase CHK1. Int J Gynecol Cancer. 2014;24:838-43 pubmed publisher
Petsalaki E, Zachos G. Chk2 prevents mitotic exit when the majority of kinetochores are unattached. J Cell Biol. 2014;205:339-56 pubmed publisher
Batson J, MacCarthy Morrogh L, Archer A, Tanton H, Nobes C. EphA receptors regulate prostate cancer cell dissemination through Vav2-RhoA mediated cell-cell repulsion. Biol Open. 2014;3:453-62 pubmed publisher
Wang S, Ma Z, Xu X, Wang Z, Sun L, Zhou Y, et al. A role of Rab29 in the integrity of the trans-Golgi network and retrograde trafficking of mannose-6-phosphate receptor. PLoS ONE. 2014;9:e96242 pubmed publisher
Larrieu D, Britton S, Demir M, Rodriguez R, Jackson S. Chemical inhibition of NAT10 corrects defects of laminopathic cells. Science. 2014;344:527-32 pubmed publisher
Lee G, Haverty P, Li L, Kljavin N, Bourgon R, Lee J, et al. Comparative oncogenomics identifies PSMB4 and SHMT2 as potential cancer driver genes. Cancer Res. 2014;74:3114-26 pubmed publisher
Yang X, Xu W, Hu Z, Zhang Y, Xu N. Chk1 is required for the metaphase-anaphase transition via regulating the expression and localization of Cdc20 and Mad2. Life Sci. 2014;106:12-8 pubmed publisher
Siriwardana N, Meyer R, Havasi A, Dominguez I, Panchenko M. Cell cycle-dependent chromatin shuttling of HBO1-JADE1 histone acetyl transferase (HAT) complex. Cell Cycle. 2014;13:1885-901 pubmed publisher
Ram R, Mendiratta S, Bodemann B, Torres M, Eskiocak U, White M. RASSF1A inactivation unleashes a tumor suppressor/oncogene cascade with context-dependent consequences on cell cycle progression. Mol Cell Biol. 2014;34:2350-8 pubmed publisher
Camps J, Wangsa D, Falke M, Brown M, Case C, Erdos M, et al. Loss of lamin B1 results in prolongation of S phase and decondensation of chromosome territories. FASEB J. 2014;28:3423-34 pubmed publisher
Park S, Yu S, Chai Y, Jang Y. CDK2-dependent phosphorylation of Suv39H1 is involved in control of heterochromatin replication during cell cycle progression. Nucleic Acids Res. 2014;42:6196-207 pubmed publisher
Landry B, Mapa C, Arsenault H, Poti K, Benanti J. Regulation of a transcription factor network by Cdk1 coordinates late cell cycle gene expression. EMBO J. 2014;33:1044-60 pubmed publisher
Nagarajan A, Dogra S, Liu A, Green M, Wajapeyee N. PEA15 regulates the DNA damage-induced cell cycle checkpoint and oncogene-directed transformation. Mol Cell Biol. 2014;34:2264-82 pubmed publisher
Wang T, Yanger K, Stanger B, Cassio D, Bi E. Cytokinesis defines a spatial landmark for hepatocyte polarization and apical lumen formation. J Cell Sci. 2014;127:2483-92 pubmed publisher
Foley K, Klip A. Dynamic GLUT4 sorting through a syntaxin-6 compartment in muscle cells is derailed by insulin resistance-causing ceramide. Biol Open. 2014;3:314-25 pubmed publisher
O Flanagan C, Morais V, Wurst W, De Strooper B, O NEILL C. The Parkinson's gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypes. Oncogene. 2015;34:1363-74 pubmed publisher
Wang W, Huang H, Kao S, Hsu Y, Wang Y, Li K, et al. Slug is temporally regulated by cyclin E in cell cycle and controls genome stability. Oncogene. 2015;34:1116-25 pubmed publisher
Kraft L, Nguyen T, Vogel S, Kenworthy A. Size, stoichiometry, and organization of soluble LC3-associated complexes. Autophagy. 2014;10:861-77 pubmed publisher
Chen Y, Lai K, Kuo H, Chow L, Yih L, Lee T. HSP70 colocalizes with PLK1 at the centrosome and disturbs spindle dynamics in cells arrested in mitosis by arsenic trioxide. Arch Toxicol. 2014;88:1711-23 pubmed publisher
Wen S, Lin Y, Yu Y, Cao S, Zhang R, Yang X, et al. miR-506 acts as a tumor suppressor by directly targeting the hedgehog pathway transcription factor Gli3 in human cervical cancer. Oncogene. 2015;34:717-25 pubmed publisher
Frezzato F, Trimarco V, Martini V, Gattazzo C, Ave E, Visentin A, et al. Leukaemic cells from chronic lymphocytic leukaemia patients undergo apoptosis following microtubule depolymerization and Lyn inhibition by nocodazole. Br J Haematol. 2014;165:659-72 pubmed publisher
Lake R, Tsai P, Choi I, Won K, Fan H. RBPJ, the major transcriptional effector of Notch signaling, remains associated with chromatin throughout mitosis, suggesting a role in mitotic bookmarking. PLoS Genet. 2014;10:e1004204 pubmed publisher
Balboula A, Schindler K. Selective disruption of aurora C kinase reveals distinct functions from aurora B kinase during meiosis in mouse oocytes. PLoS Genet. 2014;10:e1004194 pubmed publisher
Douthwright S, Sluder G. Link between DNA damage and centriole disengagement/reduplication in untransformed human cells. J Cell Physiol. 2014;229:1427-36 pubmed publisher
Joensuu M, Belevich I, Rämö O, Nevzorov I, Vihinen H, Puhka M, et al. ER sheet persistence is coupled to myosin 1c-regulated dynamic actin filament arrays. Mol Biol Cell. 2014;25:1111-26 pubmed publisher
Zhang C, Chen B, Guo A, Zhu Y, Miller J, Gao S, et al. Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure. Circulation. 2014;129:1742-50 pubmed publisher
Ostrow A, Nellimoottil T, Knott S, Fox C, Tavare S, Aparicio O. Fkh1 and Fkh2 bind multiple chromosomal elements in the S. cerevisiae genome with distinct specificities and cell cycle dynamics. PLoS ONE. 2014;9:e87647 pubmed publisher
Arnette C, Efimova N, Zhu X, Clark G, Kaverina I. Microtubule segment stabilization by RASSF1A is required for proper microtubule dynamics and Golgi integrity. Mol Biol Cell. 2014;25:800-10 pubmed publisher
Menko A, Bleaken B, Libowitz A, Zhang L, Stepp M, Walker J. A central role for vimentin in regulating repair function during healing of the lens epithelium. Mol Biol Cell. 2014;25:776-90 pubmed publisher
Atencio D, Barnes C, Duncan T, Willis I, Hanes S. The yeast Ess1 prolyl isomerase controls Swi6 and Whi5 nuclear localization. G3 (Bethesda). 2014;4:523-37 pubmed publisher
Chen S, Tang D. c-Abl tyrosine kinase regulates cytokinesis of human airway smooth muscle cells. Am J Respir Cell Mol Biol. 2014;50:1076-83 pubmed publisher
Baba T, Sakamoto Y, Kasamatsu A, Minakawa Y, Yokota S, Higo M, et al. Persephin: A potential key component in human oral cancer progression through the RET receptor tyrosine kinase-mitogen-activated protein kinase signaling pathway. Mol Carcinog. 2015;54:608-17 pubmed publisher
Sun S, Yan J, Xia C, Lin Y, Jiang X, Liu H, et al. Visualizing hepatitis B virus with biarsenical labelling in living cells. Liver Int. 2014;34:1532-42 pubmed publisher
Sohn W, Choi M, Yamamoto H, Lee S, Lee Y, Jung J, et al. Contribution of mesenchymal proliferation in tooth root morphogenesis. J Dent Res. 2014;93:78-83 pubmed publisher
Yang S, Zhang L, Liu M, Chong R, Ding S, Chen Y, et al. CDK1 phosphorylation of YAP promotes mitotic defects and cell motility and is essential for neoplastic transformation. Cancer Res. 2013;73:6722-33 pubmed publisher
Listovsky T, Sale J. Sequestration of CDH1 by MAD2L2 prevents premature APC/C activation prior to anaphase onset. J Cell Biol. 2013;203:87-100 pubmed publisher
Mirkin E, Chang F, Kleckner N. Dynamic trans interactions in yeast chromosomes. PLoS ONE. 2013;8:e75895 pubmed publisher
Krajcovic M, Krishna S, Akkari L, Joyce J, Overholtzer M. mTOR regulates phagosome and entotic vacuole fission. Mol Biol Cell. 2013;24:3736-45 pubmed publisher
Liu Y, Huang S, Chen J, Wang L. Microtubule depolymerization activates the Epstein-Barr virus lytic cycle through protein kinase C pathways in nasopharyngeal carcinoma cells. J Gen Virol. 2013;94:2750-2758 pubmed publisher
Nie J, Liu L, Xing G, Zhang M, Wei R, Guo M, et al. CKIP-1 acts as a colonic tumor suppressor by repressing oncogenic Smurf1 synthesis and promoting Smurf1 autodegradation. Oncogene. 2014;33:3677-87 pubmed publisher
Yi J, Wu X, Chung A, Chen J, Kapoor T, Hammer J. Centrosome repositioning in T cells is biphasic and driven by microtubule end-on capture-shrinkage. J Cell Biol. 2013;202:779-92 pubmed publisher
Varma D, Wan X, Cheerambathur D, Gassmann R, Suzuki A, Lawrimore J, et al. Spindle assembly checkpoint proteins are positioned close to core microtubule attachment sites at kinetochores. J Cell Biol. 2013;202:735-46 pubmed publisher
Yang S, Counter C. Cell cycle regulated phosphorylation of the telomere-associated protein TIN2. PLoS ONE. 2013;8:e71697 pubmed publisher
Bueno M, Richard S. SUMOylation negatively modulates target gene occupancy of the KDM5B, a histone lysine demethylase. Epigenetics. 2013;8:1162-75 pubmed publisher
Voss M, Campbell K, Saranzewa N, Campbell D, Hastie C, Peggie M, et al. Protein phosphatase 4 is phosphorylated and inactivated by Cdk in response to spindle toxins and interacts with ?-tubulin. Cell Cycle. 2013;12:2876-87 pubmed publisher
Bajaj M, Srayko M. Laulimalide induces dose-dependent modulation of microtubule behaviour in the C. elegans embryo. PLoS ONE. 2013;8:e71889 pubmed publisher
Genç L, Dikmen G. Preparation and characterization of nocodazole-loaded solid lipid nanoparticles. Pharm Dev Technol. 2014;19:671-6 pubmed publisher
Li L, Fothergill T, Hutchins B, Dent E, Kalil K. Wnt5a evokes cortical axon outgrowth and repulsive guidance by tau mediated reorganization of dynamic microtubules. Dev Neurobiol. 2014;74:797-817 pubmed publisher
Tien S, Chang Z. Oncogenic Shp2 disturbs microtubule regulation to cause HDAC6-dependent ERK hyperactivation. Oncogene. 2014;33:2938-46 pubmed publisher
Boeckmann L, Takahashi Y, Au W, Mishra P, Choy J, Dawson A, et al. Phosphorylation of centromeric histone H3 variant regulates chromosome segregation in Saccharomyces cerevisiae. Mol Biol Cell. 2013;24:2034-44 pubmed publisher
Shao H, Li R, Ma C, Chen E, Liu X. Xenopus oocyte meiosis lacks spindle assembly checkpoint control. J Cell Biol. 2013;201:191-200 pubmed publisher
Xia C, Nguyen M, Garrison A, Zhao Z, Wang Z, Sutherland C, et al. CNP/cGMP signaling regulates axon branching and growth by modulating microtubule polymerization. Dev Neurobiol. 2013;73:673-87 pubmed publisher
Stirbat T, Mgharbel A, Bodennec S, Ferri K, Mertani H, Rieu J, et al. Fine tuning of tissues' viscosity and surface tension through contractility suggests a new role for ?-catenin. PLoS ONE. 2013;8:e52554 pubmed publisher
Elis E, Ehrlich M, Prizan Ravid A, Laham Karam N, Bacharach E. p12 tethers the murine leukemia virus pre-integration complex to mitotic chromosomes. PLoS Pathog. 2012;8:e1003103 pubmed publisher
Volotskova O, Hawley T, Stepp M, Keidar M. Targeting the cancer cell cycle by cold atmospheric plasma. Sci Rep. 2012;2:636 pubmed publisher
Shao M, Lin Y, Liu Z, Zhang Y, Wang L, Liu C, et al. GSK-3 activity is critical for the orientation of the cortical microtubules and the dorsoventral axis determination in zebrafish embryos. PLoS ONE. 2012;7:e36655 pubmed publisher
Thakur J, Sanyal K. A coordinated interdependent protein circuitry stabilizes the kinetochore ensemble to protect CENP-A in the human pathogenic yeast Candida albicans. PLoS Genet. 2012;8:e1002661 pubmed publisher
Zacharaki P, Stephanou G, Demopoulos N. Comparison of the aneugenic properties of nocodazole, paclitaxel and griseofulvin in vitro. Centrosome defects and alterations in protein expression profiles. J Appl Toxicol. 2013;33:869-79 pubmed publisher
Kamal A, Reddy M, Shaik T, Rajender -, Srikanth Y, Reddy V, et al. Synthesis of terphenyl benzimidazoles as tubulin polymerization inhibitors. Eur J Med Chem. 2012;50:9-17 pubmed publisher
Espeut J, Cheerambathur D, Krenning L, Oegema K, Desai A. Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore. J Cell Biol. 2012;196:469-82 pubmed publisher
Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W. Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS Comput Biol. 2011;7:e1002310 pubmed publisher
Koutsopoulos O, Koch C, Tosch V, Böhm J, North K, Laporte J. Mild functional differences of dynamin 2 mutations associated to centronuclear myopathy and Charcot-Marie Tooth peripheral neuropathy. PLoS ONE. 2011;6:e27498 pubmed publisher
Rahn E, Petermann P, Hsu M, Rixon F, Knebel Mörsdorf D. Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent. PLoS ONE. 2011;6:e25464 pubmed publisher
Engelke M, Burckhardt C, Morf M, Greber U. The dynactin complex enhances the speed of microtubule-dependent motions of adenovirus both towards and away from the nucleus. Viruses. 2011;3:233-53 pubmed publisher
Mishra P, Au W, Choy J, Kuich P, Baker R, Foltz D, et al. Misregulation of Scm3p/HJURP causes chromosome instability in Saccharomyces cerevisiae and human cells. PLoS Genet. 2011;7:e1002303 pubmed publisher
Sigoillot F, Huckins J, Li F, Zhou X, Wong S, King R. A time-series method for automated measurement of changes in mitotic and interphase duration from time-lapse movies. PLoS ONE. 2011;6:e25511 pubmed publisher
Li L, Sheng L, Wang C, Zhou Y, Huang H, Li X, et al. Diterpenes from the Hainan soft coral Lobophytum cristatum Tixier-Durivault. J Nat Prod. 2011;74:2089-94 pubmed publisher
Crews L, Ruf R, Patrick C, Dumaop W, Trejo Morales M, Achim C, et al. Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders. Mol Neurodegener. 2011;6:67 pubmed publisher
Carvalho A, Olson S, Gutierrez E, Zhang K, Noble L, Zanin E, et al. Acute drug treatment in the early C. elegans embryo. PLoS ONE. 2011;6:e24656 pubmed publisher
Semenova M, Kiselyov A, Tsyganov D, Konyushkin L, Firgang S, Semenov R, et al. Polyalkoxybenzenes from plants. 5. Parsley seed extract in synthesis of azapodophyllotoxins featuring strong tubulin destabilizing activity in the sea urchin embryo and cell culture assays. J Med Chem. 2011;54:7138-49 pubmed publisher
Webster M, Zhao M, Rudek M, Hann C, Freel Meyers C. Bisphosphonamidate clodronate prodrug exhibits potent anticancer activity in non-small-cell lung cancer cells. J Med Chem. 2011;54:6647-56 pubmed publisher
Carcagno A, Marazita M, Ogara M, Ceruti J, Sonzogni S, Scassa M, et al. E2F1-mediated upregulation of p19INK4d determines its periodic expression during cell cycle and regulates cellular proliferation. PLoS ONE. 2011;6:e21938 pubmed publisher
Prinz H, Schmidt P, Böhm K, Baasner S, Muller K, Gerlach M, et al. Phenylimino-10H-anthracen-9-ones as novel antimicrotubule agents-synthesis, antiproliferative activity and inhibition of tubulin polymerization. Bioorg Med Chem. 2011;19:4183-91 pubmed publisher
Singhmar P, Kumar A. Angelman syndrome protein UBE3A interacts with primary microcephaly protein ASPM, localizes to centrosomes and regulates chromosome segregation. PLoS ONE. 2011;6:e20397 pubmed publisher
Wu G, Yu F, Xiao Z, Xu K, Xu J, Tang W, et al. Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro. Br J Cancer. 2011;105:146-53 pubmed publisher
Prinz H, Chamasmani B, Vogel K, Böhm K, Aicher B, Gerlach M, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011;54:4247-63 pubmed publisher
Torres M, Clement S, Cappell S, Dohlman H. Cell cycle-dependent phosphorylation and ubiquitination of a G protein alpha subunit. J Biol Chem. 2011;286:20208-16 pubmed publisher
Yoshimura Y, Miki H. Dynamic regulation of GEF-H1 localization at microtubules by Par1b/MARK2. Biochem Biophys Res Commun. 2011;408:322-8 pubmed publisher
Lee M, Bakir A, Nguyen K, Bachant J. The SUMO isopeptidase Ulp2p is required to prevent recombination-induced chromosome segregation lethality following DNA replication stress. PLoS Genet. 2011;7:e1001355 pubmed publisher
Dong B, Deng W, Jiang D. Distinct cytoskeleton populations and extensive crosstalk control Ciona notochord tubulogenesis. Development. 2011;138:1631-41 pubmed publisher
Arif E, Wagner M, Johnstone D, Wong H, George B, Pruthi P, et al. Motor protein Myo1c is a podocyte protein that facilitates the transport of slit diaphragm protein Neph1 to the podocyte membrane. Mol Cell Biol. 2011;31:2134-50 pubmed publisher
Bolhy S, Bouhlel I, Dultz E, Nayak T, Zuccolo M, Gatti X, et al. A Nup133-dependent NPC-anchored network tethers centrosomes to the nuclear envelope in prophase. J Cell Biol. 2011;192:855-71 pubmed publisher
Wu P, Wang Q, Dong Z, Chu E, Roberson R, Ivanova I, et al. Expression of coxsackie and adenovirus receptor distinguishes transitional cancer states in therapy-induced cellular senescence. Cell Death Dis. 2010;1:e70 pubmed publisher
Hubert T, Vandekerckhove J, Gettemans J. Unconventional actin conformations localize on intermediate filaments in mitosis. Biochem Biophys Res Commun. 2011;406:101-6 pubmed publisher
Funakoshi T, Clever M, Watanabe A, Imamoto N. Localization of Pom121 to the inner nuclear membrane is required for an early step of interphase nuclear pore complex assembly. Mol Biol Cell. 2011;22:1058-69 pubmed publisher
Kamal A, Bharathi E, Reddy J, Ramaiah M, Dastagiri D, Reddy M, et al. Synthesis and biological evaluation of 3,5-diaryl isoxazoline/isoxazole linked 2,3-dihydroquinazolinone hybrids as anticancer agents. Eur J Med Chem. 2011;46:691-703 pubmed publisher
Suresh G, Reddy P, Babu K, Shaik T, Kalivendi S. Two new cytotoxic labdane diterpenes from the rhizomes of Hedychium coronarium. Bioorg Med Chem Lett. 2010;20:7544-8 pubmed publisher
He Y, Xu K, Keiner B, Zhou J, Czudai V, Li T, et al. Influenza A virus replication induces cell cycle arrest in G0/G1 phase. J Virol. 2010;84:12832-40 pubmed publisher
Ekins S, Williams A, Xu J. A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug Metab Dispos. 2010;38:2302-8 pubmed publisher
Maciejowski J, George K, Terret M, Zhang C, Shokat K, Jallepalli P. Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling. J Cell Biol. 2010;190:89-100 pubmed publisher
Greene N, Fisk L, Naven R, Note R, Patel M, Pelletier D. Developing structure-activity relationships for the prediction of hepatotoxicity. Chem Res Toxicol. 2010;23:1215-22 pubmed publisher
Surkau G, Böhm K, Muller K, Prinz H. Synthesis, antiproliferative activity and inhibition of tubulin polymerization by anthracenone-based oxime derivatives. Eur J Med Chem. 2010;45:3354-64 pubmed publisher
Nickel H, Schmidt P, Böhm K, Baasner S, Muller K, Gerlach M, et al. Synthesis, antiproliferative activity and inhibition of tubulin polymerization by 1,5- and 1,8-disubstituted 10H-anthracen-9-ones bearing a 10-benzylidene or 10-(2-oxo-2-phenylethylidene) moiety. Eur J Med Chem. 2010;45:3420-38 pubmed publisher
Harris E, Nelson W. Adenomatous polyposis coli regulates endothelial cell migration independent of roles in beta-catenin signaling and cell-cell adhesion. Mol Biol Cell. 2010;21:2611-23 pubmed publisher
Stefely J, Palchaudhuri R, Miller P, Peterson R, Moraski G, Hergenrother P, et al. N-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)arylamide as a new scaffold that provides rapid access to antimicrotubule agents: synthesis and evaluation of antiproliferative activity against select cancer cell lines. J Med Chem. 2010;53:3389-95 pubmed publisher
Guizzunti G, Brady T, Fischer D, Malhotra V, Theodorakis E. Chemical biology studies on norrisolide. Bioorg Med Chem. 2010;18:2115-2122 pubmed publisher
Steen J, Steen J, Harrison P, Seemann T, Wilkie I, Harper M, et al. Fis is essential for capsule production in Pasteurella multocida and regulates expression of other important virulence factors. PLoS Pathog. 2010;6:e1000750 pubmed publisher
Kiselyov A, Semenova M, Chernyshova N, Leitao A, Samet A, Kislyi K, et al. Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays. Eur J Med Chem. 2010;45:1683-97 pubmed publisher
Weber J, Oakley A, Christ A, Clark A, Hayes J, Hall R, et al. Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthase. Eur J Med Chem. 2010;45:447-54 pubmed publisher
Oikonomou E, Makrodouli E, Evagelidou M, Joyce T, Probert L, Pintzas A. BRAF(V600E) efficient transformation and induction of microsatellite instability versus KRAS(G12V) induction of senescence markers in human colon cancer cells. Neoplasia. 2009;11:1116-31 pubmed
Boncompain G, Schneider B, Delevoye C, Kellermann O, Dautry Varsat A, Subtil A. Production of reactive oxygen species is turned on and rapidly shut down in epithelial cells infected with Chlamydia trachomatis. Infect Immun. 2010;78:80-7 pubmed publisher
Kile A, Koepp D. Activation of the S-phase checkpoint inhibits degradation of the F-box protein Dia2. Mol Cell Biol. 2010;30:160-71 pubmed publisher
Heaslip A, Ems McClung S, Hu K. TgICMAP1 is a novel microtubule binding protein in Toxoplasma gondii. PLoS ONE. 2009;4:e7406 pubmed publisher
Yuan J, Johnson R, Huang R, Wichterman J, Jiang H, Hayton K, et al. Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nat Chem Biol. 2009;5:765-71 pubmed publisher
Mielgo A, Torres V, Clair K, Barbero S, Stupack D. Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules. Oncogene. 2009;28:3551-62 pubmed publisher
Ayoub N, Rajendra E, Su X, Jeyasekharan A, Mahen R, Venkitaraman A. The carboxyl terminus of Brca2 links the disassembly of Rad51 complexes to mitotic entry. Curr Biol. 2009;19:1075-85 pubmed publisher
Rodriguez Collazo P, Leuba S, Zlatanova J. Robust methods for purification of histones from cultured mammalian cells with the preservation of their native modifications. Nucleic Acids Res. 2009;37:e81 pubmed publisher
Trompouki E, Tsagaratou A, Kosmidis S, Dolle P, Qian J, Kontoyiannis D, et al. Truncation of the catalytic domain of the cylindromatosis tumor suppressor impairs lung maturation. Neoplasia. 2009;11:469-76 pubmed
Theis M, Slabicki M, Junqueira M, Paszkowski Rogacz M, Sontheimer J, Kittler R, et al. Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division. EMBO J. 2009;28:1453-65 pubmed publisher
Tartakoff A, Jaiswal P. Nuclear fusion and genome encounter during yeast zygote formation. Mol Biol Cell. 2009;20:2932-42 pubmed publisher
Taylor M, Burgon T, Kirkegaard K, Jackson W. Role of microtubules in extracellular release of poliovirus. J Virol. 2009;83:6599-609 pubmed publisher
Prinz H, Schmidt P, Böhm K, Baasner S, Muller K, Unger E, et al. 10-(2-oxo-2-phenylethylidene)-10H-anthracen-9-ones as highly active antimicrotubule agents: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2009;52:1284-94 pubmed publisher
Saenz J, Sun W, Chang J, Li J, Bursulaya B, Gray N, et al. Golgicide A reveals essential roles for GBF1 in Golgi assembly and function. Nat Chem Biol. 2009;5:157-65 pubmed publisher
Prosser S, Straatman K, Fry A. Molecular dissection of the centrosome overduplication pathway in S-phase-arrested cells. Mol Cell Biol. 2009;29:1760-73 pubmed publisher
López Sánchez I, Sanz Garcia M, Lazo P. Plk3 interacts with and specifically phosphorylates VRK1 in Ser342, a downstream target in a pathway that induces Golgi fragmentation. Mol Cell Biol. 2009;29:1189-201 pubmed publisher
Waples W, Chahwan C, Ciechonska M, Lavoie B. Putting the brake on FEAR: Tof2 promotes the biphasic release of Cdc14 phosphatase during mitotic exit. Mol Biol Cell. 2009;20:245-55 pubmed publisher
Young K, Thurston S, Copeland S, Smallwood C, Copeland J. INF1 is a novel microtubule-associated formin. Mol Biol Cell. 2008;19:5168-80 pubmed publisher
Bonilla Santiago R, Wu Z, Zhang L, Widmer G. Identification of growth inhibiting compounds in a Giardia lamblia high-throughput screen. Mol Biochem Parasitol. 2008;162:149-54 pubmed publisher
Gauthier D, Sobota J, Ferraro F, Mains R, Lazure C. Flow cytometry-assisted purification and proteomic analysis of the corticotropes dense-core secretory granules. Proteomics. 2008;8:3848-61 pubmed publisher
Kumar Y, Valdivia R. Actin and intermediate filaments stabilize the Chlamydia trachomatis vacuole by forming dynamic structural scaffolds. Cell Host Microbe. 2008;4:159-69 pubmed publisher
Slawson C, Lakshmanan T, Knapp S, Hart G. A mitotic GlcNAcylation/phosphorylation signaling complex alters the posttranslational state of the cytoskeletal protein vimentin. Mol Biol Cell. 2008;19:4130-40 pubmed publisher
Hoon S, Smith A, Wallace I, Suresh S, Miranda M, Fung E, et al. An integrated platform of genomic assays reveals small-molecule bioactivities. Nat Chem Biol. 2008;4:498-506 pubmed publisher
Grim J, Gustafson M, Hirata R, Hagar A, Swanger J, Welcker M, et al. Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase. J Cell Biol. 2008;181:913-20 pubmed publisher
Fukui Y, Shindoh K, Yamamoto Y, Koyano S, Kosugi I, Yamaguchi T, et al. Establishment of a cell-based assay for screening of compounds inhibiting very early events in the cytomegalovirus replication cycle and characterization of a compound identified using the assay. Antimicrob Agents Chemother. 2008;52:2420-7 pubmed publisher
Meiser A, Mueller A, Wise E, McDonagh E, Petit S, Saran N, et al. The chemokine receptor CXCR3 is degraded following internalization and is replenished at the cell surface by de novo synthesis of receptor. J Immunol. 2008;180:6713-24 pubmed
Rantanen K, Pursiheimo J, Högel H, Himanen V, Metzen E, Jaakkola P. Prolyl hydroxylase PHD3 activates oxygen-dependent protein aggregation. Mol Biol Cell. 2008;19:2231-40 pubmed publisher
Wijeratne E, Paranagama P, Marron M, Gunatilaka M, Arnold A, Gunatilaka A. Sesquiterpene quinones and related metabolites from Phyllosticta spinarum, a fungal strain endophytic in Platycladus orientalis of the Sonoran Desert. J Nat Prod. 2008;71:218-22 pubmed publisher
Zuse A, Schmidt P, Baasner S, Böhm K, Muller K, Gerlach M, et al. Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2007;50:6059-66 pubmed
Klein E, DeBonis S, Thiede B, Skoufias D, Kozielski F, Lebeau L. New chemical tools for investigating human mitotic kinesin Eg5. Bioorg Med Chem. 2007;15:6474-88 pubmed
Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed
Zuse A, Schmidt P, Baasner S, Böhm K, Muller K, Gerlach M, et al. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2006;49:7816-25 pubmed
Peters U, Cherian J, Kim J, Kwok B, Kapoor T. Probing cell-division phenotype space and Polo-like kinase function using small molecules. Nat Chem Biol. 2006;2:618-26 pubmed
Tarby C, Kaltenbach R, Huynh T, Pudzianowski A, Shen H, Ortega Nanos M, et al. Inhibitors of human mitotic kinesin Eg5: characterization of the 4-phenyl-tetrahydroisoquinoline lead series. Bioorg Med Chem Lett. 2006;16:2095-100 pubmed
Iouk T, Kerscher O, Scott R, Basrai M, Wozniak R. The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpoint. J Cell Biol. 2002;159:807-19 pubmed
Storrie B, White J, Rottger S, Stelzer E, Suganuma T, Nilsson T. Recycling of golgi-resident glycosyltransferases through the ER reveals a novel pathway and provides an explanation for nocodazole-induced Golgi scattering. J Cell Biol. 1998;143:1505-21 pubmed
Storrie B, Yang W. Dynamics of the interphase mammalian Golgi complex as revealed through drugs producing reversible Golgi disassembly. Biochim Biophys Acta. 1998;1404:127-37 pubmed
Huby R, Weiss A, Ley S. Nocodazole inhibits signal transduction by the T cell antigen receptor. J Biol Chem. 1998;273:12024-31 pubmed
Wang T, Wang H, Ichijo H, Giannakakou P, Foster J, Fojo T, et al. Microtubule-interfering agents activate c-Jun N-terminal kinase/stress-activated protein kinase through both Ras and apoptosis signal-regulating kinase pathways. J Biol Chem. 1998;273:4928-36 pubmed
Vasquez R, Howell B, Yvon A, Wadsworth P, Cassimeris L. Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro. Mol Biol Cell. 1997;8:973-85 pubmed
Mejillano M, Shivanna B, Himes R. Studies on the nocodazole-induced GTPase activity of tubulin. Arch Biochem Biophys. 1996;336:130-8 pubmed
Luduena R, Roach M. Tubulin sulfhydryl groups as probes and targets for antimitotic and antimicrotubule agents. Pharmacol Ther. 1991;49:133-52 pubmed
Jordan M, Thrower D, Wilson L. Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis. J Cell Sci. 1992;102 ( Pt 3):401-16 pubmed
product information
Catalog Number :
M1404
Product Name :
Nocodazole
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥99% (TLC), powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA