Velazhahan V, Glaza P, Herrera A, Prakash O, Zolkiewski M, Geisbrecht B, et al. Dietary flavonoid fisetin binds human SUMO1 and blocks sumoylation of p53. PLoS ONE. 2020;15:e0234468 pubmed publisher

Rodrigues C, Nicácio A, Boeing J, Garcia F, Nakamura C, Visentainer J, et al. Rapid extraction method followed by a d-SPE clean-up step for determination of phenolic composition and antioxidant and antiproliferative activities from berry fruits. Food Chem. 2020;309:125694 pubmed publisher

Deiana P, Santona M, Dettori S, Culeddu N, Dore A, Molinu M. Multivariate approach to assess the chemical composition of Italian virgin olive oils as a function of variety and harvest period. Food Chem. 2019;300:125243 pubmed publisher

Wang E, Li Y, Maguy B, Lou Z, Wang H, Zhao W, et al. Separation and enrichment of phenolics improved the antibiofilm and antibacterial activity of the fractions from Citrus medica L. var. sarcodactylis in vitro and in tofu. Food Chem. 2019;294:533-538 pubmed publisher

Jarouche M, Suresh H, Low M, Lee S, Xu C, Khoo C. Quality Control and Variability Assessment of an Eight-Herb Formulation for Hypertension Using Method Validation and Statistical Analysis. Molecules. 2019;24: pubmed publisher

Janssens G, Lin X, Millán Ariño L, Kavšek A, Sen I, Seinstra R, et al. Transcriptomics-Based Screening Identifies Pharmacological Inhibition of Hsp90 as a Means to Defer Aging. Cell Rep. 2019;27:467-480.e6 pubmed publisher

Canal C, Ozen B, Baysal A. Characterization of antimicrobial activities of olive phenolics on yeasts using conventional methods and mid-infrared spectroscopy. J Food Sci Technol. 2019;56:149-158 pubmed publisher

Ham Y, Song H, Kwon J, Jeon H, Baek H, Kim C, et al. Effects of fermented Sorghum bicolor L. Moench extract on inflammation and thickness in a vascular cell and atherosclerotic mice model. J Nat Med. 2019;73:34-46 pubmed publisher

Da Silva J, Dos Santos R, Júnior P, Pederiva M, do Carmo Vieira M, Kassuya C, et al. Anti-inflammatory, Antioxidant and Antiproliferative Activities from Trichilia silvatica (C.DC). Curr Pharm Biotechnol. 2018;19:973-981 pubmed publisher

Kirwa H, Murungi L, Beck J, Torto B. Elicitation of Differential Responses in the Root-Knot Nematode Meloidogyne incognita to Tomato Root Exudate Cytokinin, Flavonoids, and Alkaloids. J Agric Food Chem. 2018;66:11291-11300 pubmed publisher

Li J, Dong J, Ren Y, Zhu J, Cao J, Zhang J, et al. Luteolin decreases atherosclerosis in LDL receptor-deficient mice via a mechanism including decreasing AMPK-SIRT1 signaling in macrophages. Exp Ther Med. 2018;16:2593-2599 pubmed publisher

Jiang Q, Pan D, Yang Y, Hu Y, Fang L, Shang P, et al. Luteolin Regulates Macrophage Polarization via the PI3K/Akt Pathway to Inhibit the Apoptosis Stimulated by Angiotensin II. Curr Pharm Biotechnol. 2018;19:428-437 pubmed publisher

Paz W, de Almeida R, Braga N, da Silva F, Acho L, Lima E, et al. Remela de cachorro (Clavija lancifolia Desf.) fruits from South Amazon: Phenolic composition, biological potential, and aroma analysis. Food Res Int. 2018;109:112-119 pubmed publisher

Kalogiouri N, Aalizadeh R, Thomaidis N. Application of an advanced and wide scope non-target screening workflow with LC-ESI-QTOF-MS and chemometrics for the classification of the Greek olive oil varieties. Food Chem. 2018;256:53-61 pubmed publisher

Yu Q, Zhu J, Sheng X, Xu L, Hu K, Chen G, et al. Luteolin Ameliorates Experimental Chronic Pancreatitis Induced by Trinitrobenzenesulfonic Acid in Rats. Pancreas. 2018;47:568-576 pubmed publisher

Huppke P, Weissbach S, Church J, SCHNUR R, Krusen M, Dreha Kulaczewski S, et al. Activating de novo mutations in NFE2L2 encoding NRF2 cause a multisystem disorder. Nat Commun. 2017;8:818 pubmed publisher

Wei Y, Kim T, Peng D, Duan D, Gibbons D, Yamauchi M, et al. Fibroblast-specific inhibition of TGF-?1 signaling attenuates lung and tumor fibrosis. J Clin Invest. 2017;127:3675-3688 pubmed publisher

Li X, Chen M, Lei X, Huang M, Ye W, Zhang R, et al. Luteolin inhibits angiogenesis by blocking Gas6/Axl signaling pathway. Int J Oncol. 2017;51:677-685 pubmed publisher

Atala E, Fuentes J, Wehrhahn M, Speisky H. Quercetin and related flavonoids conserve their antioxidant properties despite undergoing chemical or enzymatic oxidation. Food Chem. 2017;234:479-485 pubmed publisher

Hattori S, Kamiya T, Hara H, Ninomiya M, Koketsu M, Adachi T. CoCl2 Decreases EC-SOD Expression through Histone Deacetylation in COS7 Cells. Biol Pharm Bull. 2016;39:2036-2041 pubmed

Swar G, Shailajan S, Menon S. Activity based evaluation of a traditional Ayurvedic medicinal plant: Saraca asoca (Roxb.) de Wilde flowers as estrogenic agents using ovariectomized rat model. J Ethnopharmacol. 2017;195:324-333 pubmed publisher

Zhang B, Zhang C, Wang C, Pan D, Xu T, Li D. Luteolin Attenuates Foam Cell Formation and Apoptosis in Ox-LDL-Stimulated Macrophages by Enhancing Autophagy. Cell Physiol Biochem. 2016;39:2065-2076 pubmed

Agić D, Brkic H, Tomic S, Karačić Z, Spoljarević M, Lisjak M, et al. Validation of flavonoids as potential dipeptidyl peptidase III inhibitors: Experimental and computational approach. Chem Biol Drug Des. 2017;89:619-627 pubmed publisher

Han K, Meng W, Zhang J, Zhou Y, Wang Y, Su Y, et al. Luteolin inhibited proliferation and induced apoptosis of prostate cancer cells through miR-301. Onco Targets Ther. 2016;9:3085-94 pubmed publisher

Hytti M, Piippo N, Korhonen E, Honkakoski P, Kaarniranta K, Kauppinen A. Fisetin and luteolin protect human retinal pigment epithelial cells from oxidative stress-induced cell death and regulate inflammation. Sci Rep. 2015;5:17645 pubmed publisher

Abdel Hadi L, Di Vito C, Marfia G, Ferraretto A, Tringali C, Viani P, et al. Sphingosine Kinase 2 and Ceramide Transport as Key Targets of the Natural Flavonoid Luteolin to Induce Apoptosis in Colon Cancer Cells. PLoS ONE. 2015;10:e0143384 pubmed publisher

Barbierato M, Facci L, Marinelli C, Zusso M, Argentini C, Skaper S, et al. Co-ultramicronized Palmitoylethanolamide/Luteolin Promotes the Maturation of Oligodendrocyte Precursor Cells. Sci Rep. 2015;5:16676 pubmed publisher

Nishina A, Ukiya M, Fukatsu M, Koketsu M, Ninomiya M, Sato D, et al. Effects of Various 5,7-Dihydroxyflavone Analogs on Adipogenesis in 3T3-L1 Cells. Biol Pharm Bull. 2015;38:1794-800 pubmed publisher

Nelson K, Mathai M, Ashton J, Donkor O, Vasiljevic T, Mamilla R, et al. Effects of malted and non-malted whole-grain wheat on metabolic and inflammatory biomarkers in overweight/obese adults: a randomised crossover pilot study. Food Chem. 2016;194:495-502 pubmed publisher

Lin P, Tian X, Yi Y, Jiang W, Zhou Y, Cheng W. Luteolin-induced protection of H₂O₂-induced apoptosis in PC12 cells and the associated pathway. Mol Med Rep. 2015;12:7699-704 pubmed publisher

Patel N, Patel K, Patel K, Gandhi T. Validated HPTLC Method for Quantification of Luteolin and Apigenin in Premna mucronata Roxb., Verbenaceae. Adv Pharmacol Sci. 2015;2015:682365 pubmed publisher

Mocan A, Vodnar D, Vlase L, Crișan O, Gheldiu A, Crișan G. Phytochemical Characterization of Veronica officinalis L., V. teucrium L. and V. orchidea Crantz from Romania and Their Antioxidant and Antimicrobial Properties. Int J Mol Sci. 2015;16:21109-27 pubmed publisher

Nakayama A, Morita H, Nakao T, Yamaguchi T, Sumida T, Ikeda Y, et al. A Food-Derived Flavonoid Luteolin Protects against Angiotensin II-Induced Cardiac Remodeling. PLoS ONE. 2015;10:e0137106 pubmed publisher

Cook M, Liang Y, Besch Williford C, Goyette S, Mafuvadze B, Hyder S. Luteolin inhibits progestin-dependent angiogenesis, stem cell-like characteristics, and growth of human breast cancer xenografts. Springerplus. 2015;4:444 pubmed publisher

Wong T, Lin S, Leung L. The Flavone Luteolin Suppresses SREBP-2 Expression and Post-Translational Activation in Hepatic Cells. PLoS ONE. 2015;10:e0135637 pubmed publisher

Ng J, Hassan S, Truong T, Hocart C, Laffont C, Frugier F, et al. Flavonoids and Auxin Transport Inhibitors Rescue Symbiotic Nodulation in the Medicago truncatula Cytokinin Perception Mutant cre1. Plant Cell. 2015;27:2210-26 pubmed publisher

Mortimer M, Visser K, de Beer D, Joubert E, Louw A. Divide and Conquer May Not Be the Optimal Approach to Retain the Desirable Estrogenic Attributes of the Cyclopia Nutraceutical Extract, SM6Met. PLoS ONE. 2015;10:e0132950 pubmed publisher

Bidone J, Argenta D, Kratz J, Pettenuzzo L, Horn A, Koester L, et al. Antiherpes Activity and Skin/Mucosa Distribution of Flavonoids from Achyrocline satureioides Extract Incorporated into Topical Nanoemulsions. Biomed Res Int. 2015;2015:238010 pubmed publisher

Huang W, Tsai T, Huang C, Li Y, Chyuan J, Chuang L, et al. Inhibitory effects of wild bitter melon leaf extract on Propionibacterium acnes-induced skin inflammation in mice and cytokine production in vitro. Food Funct. 2015;6:2550-60 pubmed publisher

Wu P, Yen J, Kou M, Wu M. Luteolin and Apigenin Attenuate 4-Hydroxy-2-Nonenal-Mediated Cell Death through Modulation of UPR, Nrf2-ARE and MAPK Pathways in PC12 Cells. PLoS ONE. 2015;10:e0130599 pubmed publisher

Baiceanu E, Vlase L, Baiceanu A, Nanes M, Rusu D, Crisan G. New Polyphenols Identified in Artemisiae abrotani herba Extract. Molecules. 2015;20:11063-75 pubmed publisher

Karmakar U, Ishikawa N, Toume K, Arai M, Sadhu S, Ahmed F, et al. Sesquiterpenes with TRAIL-resistance overcoming activity from Xanthium strumarium. Bioorg Med Chem. 2015;23:4746-54 pubmed publisher

Iakovleva I, Begum A, Pokrzywa M, Walfridsson M, Sauer Eriksson A, Olofsson A. The flavonoid luteolin, but not luteolin-7-O-glucoside, prevents a transthyretin mediated toxic response. PLoS ONE. 2015;10:e0128222 pubmed publisher

Funaki A, Waki T, Noguchi A, Kawai Y, Yamashita S, Takahashi S, et al. Identification of a Highly Specific Isoflavone 7-O-glucosyltransferase in the soybean (Glycine max (L.) Merr.). Plant Cell Physiol. 2015;56:1512-20 pubmed publisher

Toma C, Olah N, Vlase L, Mogosan C, Mocan A. Comparative Studies on Polyphenolic Composition, Antioxidant and Diuretic Effects of Nigella sativa L. (Black Cumin) and Nigella damascena L. (Lady-in-a-Mist) Seeds. Molecules. 2015;20:9560-74 pubmed publisher

Grzegorczyk Karolak I, Wysokinska H, Olas B. Studies on the antioxidant properties of extracts from the roots and shoots of two Scutellaria species in human blood plasma. Acta Biochim Pol. 2015;62:253-8 pubmed publisher

Davies A, Reipas K, Hu K, Berns R, Firmino N, Stratford A, et al. Inhibition of RSK with the novel small-molecule inhibitor LJI308 overcomes chemoresistance by eliminating cancer stem cells. Oncotarget. 2015;6:20570-7 pubmed

Wabaidur S, Ahmed Y, Alothman Z, Obbed M, AL Harbi N, AL Turki T. Ultra high performance liquid chromatography with mass spectrometry method for the simultaneous determination of phenolic constituents in honey from various floral sources using multiwalled carbon nanotubes as extraction sorbents. J Sep Sci. 2015;38:2597-606 pubmed publisher

Ashida H, Harada K, Mishima S, Mitani T, Yamashita Y, Matsumura F. Luteolin suppresses TCDD-induced wasting syndrome in a cultured adipocyte model. Pestic Biochem Physiol. 2015;120:14-20 pubmed publisher

Yamauchi K, Mitsunaga T, Itakura Y, Batubara I. Extracellular melanogenesis inhibitory activity and the structure-activity relationships of ugonins from Helminthostachys zeylanica roots. Fitoterapia. 2015;104:69-74 pubmed publisher

Sato Y, Sasaki N, Saito M, Endo N, Kugawa F, Ueno A. Luteolin attenuates doxorubicin-induced cytotoxicity to MCF-7 human breast cancer cells. Biol Pharm Bull. 2015;38:703-9 pubmed publisher

Poudel B, Nepali S, Xin M, Ki H, Kim Y, Kim D, et al. Flavonoids from Triticum aestivum inhibit adipogenesis in 3T3-L1 cells by upregulating the insig pathway. Mol Med Rep. 2015;12:3139-45 pubmed publisher

Gašić U, Sikoparija B, Tosti T, Trifković J, Milojković Opsenica D, Natić M, et al. Phytochemical fingerprints of lime honey collected in serbia. J AOAC Int. 2014;97:1259-67 pubmed publisher

Blacher E, Dadali T, Bespalko A, Haupenthal V, Grimm M, Hartmann T, et al. Alzheimer's disease pathology is attenuated in a CD38-deficient mouse model. Ann Neurol. 2015;78:88-103 pubmed publisher

Chen P, Wu M, Chang H, Tai M, Ho C, Yen J. Up-Regulation of miR-34a Expression in Response to the Luteolin-Induced Neurite Outgrowth of PC12 Cells. J Agric Food Chem. 2015;63:4148-59 pubmed publisher

Jeon Y, Ahn Y, Chung W, Choi H, Suh Y. Synergistic effect between celecoxib and luteolin is dependent on estrogen receptor in human breast cancer cells. Tumour Biol. 2015;36:6349-59 pubmed publisher

Hossen M, Jeon S, Kim S, Kim J, Jeong D, Sung N, et al. In vitro and in vivo anti-inflammatory activity of Phyllanthus acidus methanolic extract. J Ethnopharmacol. 2015;168:217-28 pubmed publisher

Zhang Q, Cheng G, Qiu H, Zhu L, Ren Z, Zhao W, et al. The p53-inducible gene 3 involved in flavonoid-induced cytotoxicity through the reactive oxygen species-mediated mitochondrial apoptotic pathway in human hepatoma cells. Food Funct. 2015;6:1518-25 pubmed publisher

Liu L, Peng Z, Xu Z, Wei X. Effect of luteolin and apigenin on the expression of Oct-4, Sox2, and c-Myc in dental pulp cells with in vitro culture. Biomed Res Int. 2015;2015:534952 pubmed publisher

Nakamura K, Yang J, Sato E, Miura N, Wu Y. Effects of Hydroxy Groups in the A-Ring on the Anti-proteasome Activity of Flavone. Biol Pharm Bull. 2015;38:935-40 pubmed publisher

Malisauskas R, Botyriute A, Cannon J, Smirnovas V. Flavone derivatives as inhibitors of insulin amyloid-like fibril formation. PLoS ONE. 2015;10:e0121231 pubmed publisher

Klen T, Wondra A, Vrhovsek U, Vodopivec B. Phenolic Profiling of Olives and Olive Oil Process-Derived Matrices Using UPLC-DAD-ESI-QTOF-HRMS Analysis. J Agric Food Chem. 2015;63:3859-72 pubmed publisher

Chen L, Kotani A, Kusu F, Wang Z, Zhu J, Hakamata H. Quantitative comparison of caffeoylquinic acids and flavonoids in Chrysanthemum morifolium flowers and their sulfur-fumigated products by three-channel liquid chromatography with electrochemical detection. Chem Pharm Bull (Tokyo). 2015;63:25-32 pubmed publisher

Lin C, Lin Y, Lin R, Huang W, Lee M. Neurocytoprotective Effects of Aliphatic Hydroxamates from Lovastatin, a Secondary Metabolite from Monascus-Fermented Red Mold Rice, in 6-Hydroxydopamine (6-OHDA)-Treated Nerve Growth Factor (NGF)-Differentiated PC12 Cells. ACS Chem Neurosci. 2015;6:716-24 pubmed publisher

Guo P, Yan W, Han Q, Wang C, Zhang Z. Simultaneous quantification of 25 active constituents in the total flavonoids extract from Herba Desmodii Styracifolii by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry. J Sep Sci. 2015;38:1156-63 pubmed publisher

Cho H, Ahn K, Choi J, Hwang S, Kim W, Um H, et al. Luteolin acts as a radiosensitizer in non‑small cell lung cancer cells by enhancing apoptotic cell death through activation of a p38/ROS/caspase cascade. Int J Oncol. 2015;46:1149-58 pubmed publisher

Guzelmeric E, Vovk I, Yesilada E. Development and validation of an HPTLC method for apigenin 7-O-glucoside in chamomile flowers and its application for fingerprint discrimination of chamomile-like materials. J Pharm Biomed Anal. 2015;107:108-18 pubmed publisher

Barrajón Catalán E, Taamalli A, Quirantes Piné R, Roldan Segura C, Arráez Román D, Segura Carretero A, et al. Differential metabolomic analysis of the potential antiproliferative mechanism of olive leaf extract on the JIMT-1 breast cancer cell line. J Pharm Biomed Anal. 2015;105:156-62 pubmed publisher

Gou Y, Zhang Y, Qi J, Kong L, Zhou Z, Liang S, et al. Binding and Anticancer Properties of Plumbagin with Human Serum Albumin. Chem Biol Drug Des. 2015;86:362-9 pubmed publisher

Weng Z, Patel A, Panagiotidou S, Theoharides T. The novel flavone tetramethoxyluteolin is a potent inhibitor of human mast cells. J Allergy Clin Immunol. 2015;135:1044-52.e5 pubmed publisher

Nash L, Sullivan P, Peters S, Ward W. Rooibos flavonoids, orientin and luteolin, stimulate mineralization in human osteoblasts through the Wnt pathway. Mol Nutr Food Res. 2015;59:443-53 pubmed publisher

Sasaki N, Nishizaki Y, Yamada E, Tatsuzawa F, Nakatsuka T, Takahashi H, et al. Identification of the glucosyltransferase that mediates direct flavone C-glucosylation in Gentiana triflora. FEBS Lett. 2015;589:182-7 pubmed publisher

Pratheeshkumar P, Son Y, Divya S, Roy R, Hitron J, Wang L, et al. Luteolin inhibits Cr(VI)-induced malignant cell transformation of human lung epithelial cells by targeting ROS mediated multiple cell signaling pathways. Toxicol Appl Pharmacol. 2014;281:230-41 pubmed publisher

Figueroa Pérez M, Rocha Guzman N, Pérez Ramírez I, Mercado Silva E, Reynoso Camacho R. Metabolite profile, antioxidant capacity, and inhibition of digestive enzymes in infusions of peppermint (Mentha piperita) grown under drought stress. J Agric Food Chem. 2014;62:12027-33 pubmed publisher

Nalewajko Sieliwoniuk E, Malejko J, Mozolewska M, Wołyniec E, Nazaruk J. Determination of polyphenolic compounds in Cirsium palustre (L.) extracts by high performance liquid chromatography with chemiluminescence detection. Talanta. 2015;133:38-44 pubmed publisher

Lamy S, Moldovan P, Ben Saad A, Annabi B. Biphasic effects of luteolin on interleukin-1β-induced cyclooxygenase-2 expression in glioblastoma cells. Biochim Biophys Acta. 2015;1853:126-35 pubmed publisher

Wang T, Pan D, Zhang Y, Li D, Zhang Y, Xu T, et al. Luteolin antagonizes angiotensin II-dependent proliferation and collagen synthesis of cultured rat cardiac fibroblasts. Curr Pharm Biotechnol. 2015;16:430-9 pubmed

Bekdeser B, Durusoy N, Ozyurek M, Güçlü K, Apak R. Optimization of microwave-assisted extraction of polyphenols from herbal teas and evaluation of their in vitro hypochlorous acid scavenging activity. J Agric Food Chem. 2014;62:11109-15 pubmed publisher

Kim Y, Kim S, Shin J, Harikishore A, Lim J, Jung Y, et al. Luteolin suppresses cancer cell proliferation by targeting vaccinia-related kinase 1. PLoS ONE. 2014;9:e109655 pubmed publisher

El Senousy A, Farag M, Al Mahdy D, Wessjohann L. Developmental changes in leaf phenolics composition from three artichoke cvs. (Cynara scolymus) as determined via UHPLC-MS and chemometrics. Phytochemistry. 2014;108:67-76 pubmed publisher

Lee H, Seo H, Ryu J, Yoon Y, Park S, Lee C. Luteolin inhibited the gene expression, production and secretion of MUC5AC mucin via regulation of nuclear factor kappa B signaling pathway in human airway epithelial cells. Pulm Pharmacol Ther. 2015;31:117-22 pubmed publisher

Gray A, Stephens C, Bigelow R, Coleman D, Cardelli J. The polyphenols (-)-epigallocatechin-3-gallate and luteolin synergistically inhibit TGF-β-induced myofibroblast phenotypes through RhoA and ERK inhibition. PLoS ONE. 2014;9:e109208 pubmed publisher

Zielińska Pisklak M, Kaliszewska D, Stolarczyk M, Kiss A. Activity-guided isolation, identification and quantification of biologically active isomeric compounds from folk medicinal plant Desmodium adscendens using high performance liquid chromatography with diode array detector, mass spectrometry and multid. J Pharm Biomed Anal. 2015;102:54-63 pubmed publisher

Balogun S, da Silva I, Colodel E, de Oliveira R, Ascêncio S, Martins D. Toxicological evaluation of hydroethanolic extract of Helicteres sacarolha A. St.- Hil. et al. J Ethnopharmacol. 2014;157:285-91 pubmed publisher

Johnson J, Dia V, Wallig M, Gonzalez de Mejia E. Luteolin and Gemcitabine Protect Against Pancreatic Cancer in an Orthotopic Mouse Model. Pancreas. 2015;44:144-51 pubmed publisher

Ramírez E, Medina E, Brenes M, Romero C. Endogenous enzymes involved in the transformation of oleuropein in Spanish table olive varieties. J Agric Food Chem. 2014;62:9569-75 pubmed publisher

Materska M, Konopacka M, Rogoliński J, Ślosarek K. Antioxidant activity and protective effects against oxidative damage of human cells induced by X-radiation of phenolic glycosides isolated from pepper fruits Capsicum annuum L. Food Chem. 2015;168:546-53 pubmed publisher

Cheng J, Chen X, Zhao S, Zhang Y. Antioxidant-capacity-based models for the prediction of acrylamide reduction by flavonoids. Food Chem. 2015;168:90-9 pubmed publisher

Chou C, Liu C, Yang D, Wu Y, Chen Y. Amino acid, mineral, and polyphenolic profiles of black vinegar, and its lipid lowering and antioxidant effects in vivo. Food Chem. 2015;168:63-9 pubmed publisher

Ribeiro D, Freitas M, Tomé S, Silva A, Laufer S, Lima J, et al. Flavonoids inhibit COX-1 and COX-2 enzymes and cytokine/chemokine production in human whole blood. Inflammation. 2015;38:858-70 pubmed publisher

Mahfoudhi A, Prencipe F, Mighri Z, Pellati F. Metabolite profiling of polyphenols in the Tunisian plant Tamarix aphylla (L.) Karst. J Pharm Biomed Anal. 2014;99:97-105 pubmed publisher

Gazal M, Ortmann C, Martins F, Streck E, Quevedo J, de Campos A, et al. Antidepressant-like effects of aqueous extract from Cecropia pachystachya leaves in a mouse model of chronic unpredictable stress. Brain Res Bull. 2014;108:10-7 pubmed publisher

Isoda H, Motojima H, Onaga S, Samet I, Villareal M, Han J. Analysis of the erythroid differentiation effect of flavonoid apigenin on K562 human chronic leukemia cells. Chem Biol Interact. 2014;220:269-77 pubmed publisher

Fridén M, Sjöberg P. Strategies for differentiation of isobaric flavonoids using liquid chromatography coupled to electrospray ionization mass spectrometry. J Mass Spectrom. 2014;49:646-63 pubmed publisher

Li J, Li X, Xu W, Wang S, Hu Z, Zhang Q, et al. Antifibrotic effects of luteolin on hepatic stellate cells and liver fibrosis by targeting AKT/mTOR/p70S6K and TGF?/Smad signalling pathways. Liver Int. 2015;35:1222-33 pubmed publisher

Kang B, Ryu J, Lee C, Hwang S. Luteolin Inhibits the Activity, Secretion and Gene Expression of MMP-3 in Cultured Articular Chondrocytes and Production of MMP-3 in the Rat Knee. Biomol Ther (Seoul). 2014;22:239-45 pubmed publisher

An G, Wang X, Morris M. Flavonoids are inhibitors of human organic anion transporter 1 (OAT1)-mediated transport. Drug Metab Dispos. 2014;42:1357-66 pubmed publisher

Aneknan P, Kukongviriyapan V, Prawan A, Kongpetch S, Sripa B, Senggunprai L. Luteolin arrests cell cycling, induces apoptosis and inhibits the JAK/STAT3 pathway in human cholangiocarcinoma cells. Asian Pac J Cancer Prev. 2014;15:5071-6 pubmed

Choi J, Islam M, Ali M, Kim Y, Park H, Sohn H, et al. The effects of C-glycosylation of luteolin on its antioxidant, anti-Alzheimer's disease, anti-diabetic, and anti-inflammatory activities. Arch Pharm Res. 2014;37:1354-63 pubmed publisher

Wu H, Huang M, Liu Y, Shu Y, Liu P. Luteolin Induces Apoptosis by Up-regulating miR-34a in Human Gastric Cancer Cells. Technol Cancer Res Treat. 2015;14:747-55 pubmed publisher

Sakurai M, Ozaki Y, Okuzaki D, Naito Y, Sasakura T, Okamoto A, et al. Gefitinib and luteolin cause growth arrest of human prostate cancer PC-3 cells via inhibition of cyclin G-associated kinase and induction of miR-630. PLoS ONE. 2014;9:e100124 pubmed publisher

Liu Q, Yang Q, Hu H, Yang L, Yang Y, Chou G, et al. Bioactive diterpenoids and flavonoids from the aerial parts of Scoparia dulcis. J Nat Prod. 2014;77:1594-600 pubmed publisher

Khan J, Alexander A, Ajazuddin -, Saraf S, Saraf S. Luteolin-phospholipid complex: preparation, characterization and biological evaluation. J Pharm Pharmacol. 2014;66:1451-62 pubmed publisher

Zhang T, Kimura Y, Jiang S, Harada K, Yamashita Y, Ashida H. Luteolin modulates expression of drug-metabolizing enzymes through the AhR and Nrf2 pathways in hepatic cells. Arch Biochem Biophys. 2014;557:36-46 pubmed publisher

Sun Y, Wu H, Wang J, Liu Z, Zhai M, Yu R. Simultaneous determination of eight flavonoids in propolis using chemometrics-assisted high performance liquid chromatography-diode array detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;962:59-67 pubmed publisher

Yan T, Li L, Sun B, Liu F, Yang P, Chen T, et al. Luteolin inhibits behavioral sensitization by blocking methamphetamine-induced MAPK pathway activation in the caudate putamen in mice. PLoS ONE. 2014;9:e98981 pubmed publisher

Yang C, Tan D, Hsu W, Jong T, Wen C, Hsu S, et al. Anti-influenza virus activity of the ethanolic extract from Peperomia sui. J Ethnopharmacol. 2014;155:320-5 pubmed publisher

Kim E, Yoon K, Lee W, Yang W, Kim S, Sung N, et al. Syk/Src-targeted anti-inflammatory activity of Codariocalyx motorius ethanolic extract. J Ethnopharmacol. 2014;155:185-93 pubmed publisher

Zhu L, Bi W, Lu D, Zhang C, Shu X, Wang H, et al. Regulation of ubiquitin-specific processing protease 8 suppresses neuroinflammation. Mol Cell Neurosci. 2015;64:74-83 pubmed publisher

Nekohashi M, Ogawa M, Ogihara T, Nakazawa K, Kato H, Misaka T, et al. Luteolin and quercetin affect the cholesterol absorption mediated by epithelial cholesterol transporter niemann-pick c1-like 1 in caco-2 cells and rats. PLoS ONE. 2014;9:e97901 pubmed publisher

Koirala N, Pandey R, Parajuli P, Jung H, Sohng J. Methylation and subsequent glycosylation of 7,8-dihydroxyflavone. J Biotechnol. 2014;184:128-37 pubmed publisher

Hu L, Yen J, Shen Y, Wu K, Wu M. Luteolin modulates 6-hydroxydopamine-induced transcriptional changes of stress response pathways in PC12 cells. PLoS ONE. 2014;9:e97880 pubmed publisher

Kenny O, Smyth T, Walsh D, Kelleher C, Hewage C, Brunton N. Investigating the potential of under-utilised plants from the Asteraceae family as a source of natural antimicrobial and antioxidant extracts. Food Chem. 2014;161:79-86 pubmed publisher

Liu G, Zhang Y, Liu C, Xu D, Zhang R, Cheng Y, et al. Luteolin alleviates alcoholic liver disease induced by chronic and binge ethanol feeding in mice. J Nutr. 2014;144:1009-15 pubmed publisher

Lou Q, Liu Y, Qi Y, Jiao S, Tian F, Jiang L, et al. Transcriptome sequencing and metabolite analysis reveals the role of delphinidin metabolism in flower colour in grape hyacinth. J Exp Bot. 2014;65:3157-64 pubmed publisher

Ham S, Kim K, Kwon T, Bak Y, Lee D, Song Y, et al. Luteolin induces intrinsic apoptosis via inhibition of E6/E7 oncogenes and activation of extrinsic and intrinsic signaling pathways in HPV-18-associated cells. Oncol Rep. 2014;31:2683-91 pubmed publisher

Zhang T, Wu W, Li D, Xu T, Zhu H, Pan D, et al. Anti-oxidant and anti-apoptotic effects of luteolin on mice peritoneal macrophages stimulated by angiotensin II. Int Immunopharmacol. 2014;20:346-51 pubmed publisher

Schöbel N, Radtke D, Kyereme J, Wollmann N, Cichy A, Obst K, et al. Astringency is a trigeminal sensation that involves the activation of G protein-coupled signaling by phenolic compounds. Chem Senses. 2014;39:471-87 pubmed publisher

Ou Y, Li J, Kuan Y, Raung S, Wang C, Hung Y, et al. Luteolin sensitizes human 786-O renal cell carcinoma cells to TRAIL-induced apoptosis. Life Sci. 2014;100:110-7 pubmed publisher

Yang M, Wang C, Chen N, Ho W, Lu F, Tseng T. Luteolin enhances paclitaxel-induced apoptosis in human breast cancer MDA-MB-231 cells by blocking STAT3. Chem Biol Interact. 2014;213:60-8 pubmed publisher

Chen Y, Huang Q, Lin X, Wei J. [Protective effect of isoorientin on alcohol-induced hepatic fibrosis in rats]. Zhongguo Zhong Yao Za Zhi. 2013;38:3726-30 pubmed

Kritas S, Saggini A, Varvara G, Murmura G, Caraffa A, Antinolfi P, et al. Luteolin inhibits mast cell-mediated allergic inflammation. J Biol Regul Homeost Agents. 2013;27:955-9 pubmed

Ding S, Hu A, Hu Y, Ma J, Weng P, Dai J. Anti-hepatoma cells function of luteolin through inducing apoptosis and cell cycle arrest. Tumour Biol. 2014;35:3053-60 pubmed publisher

Rossbach S, Kunze K, Albert S, Zehner S, Göttfert M. The Sinorhizobium meliloti EmrAB efflux system is regulated by flavonoids through a TetR-like regulator (EmrR). Mol Plant Microbe Interact. 2014;27:379-87 pubmed publisher

Wang Y, Zhou L, Gong X. [Pro-apoptotic effects of luteolin on hepatoma HepG2 cells]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2013;42:504-10 pubmed

Chen K, Chen C, Lin C, Lin C, Yang T, Chen T, et al. Luteolin attenuates TGF-β1-induced epithelial-mesenchymal transition of lung cancer cells by interfering in the PI3K/Akt-NF-κB-Snail pathway. Life Sci. 2013;93:924-33 pubmed publisher

Wang F, Jiang Y, Wang X, Lin S, Pu P, Zhu C, et al. [Chemical constituents from flower buds of Lonicera japonica]. Zhongguo Zhong Yao Za Zhi. 2013;38:1378-85 pubmed

Manjolin L, dos Reis M, Maquiaveli C, Santos Filho O, da Silva E. Dietary flavonoids fisetin, luteolin and their derived compounds inhibit arginase, a central enzyme in Leishmania (Leishmania) amazonensis infection. Food Chem. 2013;141:2253-62 pubmed publisher

Tu S, Ho C, Liu M, Huang C, Chang H, Chang C, et al. Luteolin sensitises drug-resistant human breast cancer cells to tamoxifen via the inhibition of cyclin E2 expression. Food Chem. 2013;141:1553-61 pubmed publisher

Liu B, Li W, Zhao J, Liu Y, Zhu X, Liang G. Physicochemical characterisation of the supramolecular structure of luteolin/cyclodextrin inclusion complex. Food Chem. 2013;141:900-6 pubmed publisher

Orhan F, Gulluce M, Ozkan H, Alpsoy L. Determination of the antigenotoxic potencies of some luteolin derivatives by using a eukaryotic cell system, Saccharomyces cerevisiae. Food Chem. 2013;141:366-72 pubmed publisher

Sun Y, Zhao J, Jin H, Cao Y, Ming T, Zhang L, et al. Vasorelaxant effects of the extracts and some flavonoids from the buds of Coreopsis tinctoria. Pharm Biol. 2013;51:1158-64 pubmed publisher

Liu Y, Gou L, Tian X, Fu X, Ling X, Sun L, et al. Protective effects of luteolin on cognitive impairments induced by psychological stress in mice. Exp Biol Med (Maywood). 2013;238:418-25 pubmed publisher

Wang H, Geng C, Ma Y, Zhang X, Chen J. Three new secoiridoids, swermacrolactones A-C and anti-hepatitis B virus activity from Swertia macrosperma. Fitoterapia. 2013;89:183-7 pubmed publisher

Li D, Zhong Y, Zhou Y, Sun H, Zheng X, Zhao C, et al. Autocrine TNF-?-mediated NF-?B activation is a determinant for evasion of CD40-induced cytotoxicity in cancer cells. Biochem Biophys Res Commun. 2013;436:467-72 pubmed publisher

Gökbulut A, Ozhan O, Satilmis B, Batcioglu K, Gunal S, Sarer E. Antioxidant and antimicrobial activities, and phenolic compounds of selected Inula species from Turkey. Nat Prod Commun. 2013;8:475-8 pubmed

Jiang D, Li D, Wu W. Inhibitory effects and mechanisms of luteolin on proliferation and migration of vascular smooth muscle cells. Nutrients. 2013;5:1648-59 pubmed publisher

Cheng W, Chiao M, Liang Y, Yang Y, Shen C, Yang C. Luteolin inhibits migration of human glioblastoma U-87 MG and T98G cells through downregulation of Cdc42 expression and PI3K/AKT activity. Mol Biol Rep. 2013;40:5315-26 pubmed publisher

Kozan E, Anul S, Tatli I. In vitro anthelmintic effect of Vicia pannonica var. purpurascens on trichostrongylosis in sheep. Exp Parasitol. 2013;134:299-303 pubmed publisher

Li L, Wu X, Chen Z, Sun S, Ye J, Zeng S, et al. Interspecies difference of luteolin and apigenin after oral administration of Chrysanthemum morifolium extract and prediction of human pharmacokinetics. Pharmazie. 2013;68:195-200 pubmed

Conti P, Varvara G, Murmura G, Tete S, Sabatino G, Saggini A, et al. Comparison of beneficial actions of non-steroidal anti-inflammatory drugs to flavonoids. J Biol Regul Homeost Agents. 2013;27:1-7 pubmed

Ou Y, Kuan Y, Li J, Raung S, Wang C, Hung Y, et al. Induction of apoptosis by luteolin involving akt inactivation in human 786-o renal cell carcinoma cells. Evid Based Complement Alternat Med. 2013;2013:109105 pubmed publisher

Xing X, Zhang Q, Feng F, Liu W. [Chemical constituents from stems of Ilex pubescens]. Zhong Yao Cai. 2012;35:1429-31 pubmed

Kulza M, Malinowska K, Wozniak A, Seńczuk Przybyłowska M, Nowak G, Florek E. [Development and validation of method for the determination of cynarin, luteolin in plasma]. Przegl Lek. 2012;69:987-91 pubmed

Chin Y, Kong J, Han S. Flavonoids as receptor tyrosine kinase FLT3 inhibitors. Bioorg Med Chem Lett. 2013;23:1768-70 pubmed publisher

Simirgiotis M, Schmeda Hirschmann G, Borquez J, Kennelly E. The Passiflora tripartita (Banana Passion) fruit: a source of bioactive flavonoid C-glycosides isolated by HSCCC and characterized by HPLC–DAD–ESI/MS/MS. Molecules. 2013;18:1672-92 pubmed publisher

Wang T, Wang S, Huang G, Sun G. Luteolin induced-growth inhibition and apoptosis of human esophageal squamous carcinoma cell line Eca109 cells in vitro. Asian Pac J Cancer Prev. 2012;13:5455-61 pubmed

Pratheeshkumar P, Son Y, Budhraja A, Wang X, Ding S, Wang L, et al. Luteolin inhibits human prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis. PLoS ONE. 2012;7:e52279 pubmed publisher

Tang L, Jia W. A comparison study on the binding of hesperetin and luteolin to bovine serum albumin by spectroscopy. Spectrochim Acta A Mol Biomol Spectrosc. 2013;103:114-9 pubmed publisher

Xu T, Li D, Jiang D. Targeting cell signaling and apoptotic pathways by luteolin: cardioprotective role in rat cardiomyocytes following ischemia/reperfusion. Nutrients. 2012;4:2008-19 pubmed publisher

Jeon Y, Suh Y. Synergistic apoptotic effect of celecoxib and luteolin on breast cancer cells. Oncol Rep. 2013;29:819-25 pubmed publisher

Falé P, Ascensão L, Serralheiro M. Effect of luteolin and apigenin on rosmarinic acid bioavailability in Caco-2 cell monolayers. Food Funct. 2013;4:426-31 pubmed publisher

Yuan L, Wang J, Xiao H, Wu W, Wang Y, Liu X. MAPK signaling pathways regulate mitochondrial-mediated apoptosis induced by isoorientin in human hepatoblastoma cancer cells. Food Chem Toxicol. 2013;53:62-8 pubmed publisher

Jin C, Wu D, Yu N, Chen H, Wang T, Zhang W. [The influence of different processing on the content of flavones of Dendranthema morifolium]. Zhong Yao Cai. 2012;35:702-4 pubmed

Park H, Chung B, Lee M, Song Y, Lee S, Chu G, et al. Centipede grass exerts anti-adipogenic activity through inhibition of C/EBP?, C/EBP?, and PPAR? expression and the AKT signaling pathway in 3T3-L1 adipocytes. BMC Complement Altern Med. 2012;12:230 pubmed publisher

Zhu M, Chen D, Li D, Ding H, Zhang T, Xu T, et al. Luteolin inhibits angiotensin II-induced human umbilical vein endothelial cell proliferation and migration through downregulation of Src and Akt phosphorylation. Circ J. 2013;77:772-9 pubmed

Eumkeb G, Siriwong S, Thumanu K. Synergistic activity of luteolin and amoxicillin combination against amoxicillin-resistant Escherichia coli and mode of action. J Photochem Photobiol B. 2012;117:247-53 pubmed publisher

Yin R, Han F, Tang Z, Liu R, Zhao X, Chen X, et al. UFLC-MS/MS method for simultaneous determination of luteolin-7-O-gentiobioside, luteolin-7-O-β-D-glucoside and luteolin-7-O-β-D-glucuronide in beagle dog plasma and its application to a pharmacokinetic study after administration of traditional Chines. J Pharm Biomed Anal. 2013;72:127-33 pubmed publisher

Quirantes Piné R, Zurek G, Barrajón Catalán E, Bäßmann C, Micol V, Segura Carretero A, et al. A metabolite-profiling approach to assess the uptake and metabolism of phenolic compounds from olive leaves in SKBR3 cells by HPLC-ESI-QTOF-MS. J Pharm Biomed Anal. 2013;72:121-6 pubmed publisher

Fu J, Chen D, Zhao B, Zhao Z, Zhou J, Xu Y, et al. Luteolin induces carcinoma cell apoptosis through binding Hsp90 to suppress constitutive activation of STAT3. PLoS ONE. 2012;7:e49194 pubmed publisher

Ha T, Lee M, Kim H, Kwon H, Baek I, Kubo I, et al. Slow-binding inhibition of soybean lipoxygenase-1 by luteolin. Arch Pharm Res. 2012;35:1811-6 pubmed publisher

Verschooten L, Barrette K, Van Kelst S, Rubio Romero N, Proby C, De Vos R, et al. Autophagy inhibitor chloroquine enhanced the cell death inducing effect of the flavonoid luteolin in metastatic squamous cell carcinoma cells. PLoS ONE. 2012;7:e48264 pubmed publisher

Park S, Cho C, Jun H, Ryu N, Kim J, Yu Y, et al. Anti-angiogenic effect of luteolin on retinal neovascularization via blockade of reactive oxygen species production. Invest Ophthalmol Vis Sci. 2012;53:7718-26 pubmed publisher

Awaad A, Al Jaber N, Moses J, El Meligy R, Zain M. Antiulcerogenic activities of the extracts and isolated flavonoids of Euphorbia cuneata Vahl. Phytother Res. 2013;27:126-30 pubmed publisher

Lee W, Jung H, Choi J, Kim Y, Lee S. Protective effects of luteolin against apoptotic liver damage induced by D-galactosamine/lipopolysaccharide in mice. J Nat Prod. 2011;74:1916-21 pubmed publisher

Kantevari S, Addla D, Bagul P, Sridhar B, Banerjee S. Synthesis and evaluation of novel 2-butyl-4-chloro-1-methylimidazole embedded chalcones and pyrazoles as angiotensin converting enzyme (ACE) inhibitors. Bioorg Med Chem. 2011;19:4772-81 pubmed publisher

Kellenberger E, Kuhn I, Schuber F, Muller Steffner H. Flavonoids as inhibitors of human CD38. Bioorg Med Chem Lett. 2011;21:3939-42 pubmed publisher

Matsuda H, Kogami Y, Nakamura S, Sugiyama T, Ueno T, Yoshikawa M. Structural requirements of flavonoids for the adipogenesis of 3T3-L1 cells. Bioorg Med Chem. 2011;19:2835-41 pubmed publisher

Androutsopoulos V, Papakyriakou A, Vourloumis D, Spandidos D. Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids. Bioorg Med Chem. 2011;19:2842-9 pubmed publisher

Versiani M, Diyabalanage T, Ratnayake R, Henrich C, Bates S, McMahon J, et al. Flavonoids from eight tropical plant species that inhibit the multidrug resistance transporter ABCG2. J Nat Prod. 2011;74:262-6 pubmed publisher

Toume K, Nakazawa T, Ohtsuki T, Arai M, Koyano T, Kowithayakorn T, et al. Cycloartane triterpenes isolated from Combretum quadrangulare in a screening program for death-receptor expression enhancing activity. J Nat Prod. 2011;74:249-55 pubmed publisher

Lee C, Liao Y, Hwang T, Wu C, Chang F, Wu Y. Ixorapeptide I and ixorapeptide II, bioactive peptides isolated from Ixora coccinea. Bioorg Med Chem Lett. 2010;20:7354-7 pubmed publisher

Zhang J, Liu X, Lei X, Wang L, Guo L, Zhao G, et al. Discovery and synthesis of novel luteolin derivatives as DAT agonists. Bioorg Med Chem. 2010;18:7842-8 pubmed publisher

Kuhn I, Kellenberger E, Said Hassane F, Villa P, Rognan D, Lobstein A, et al. Identification by high-throughput screening of inhibitors of Schistosoma mansoni NAD(+) catabolizing enzyme. Bioorg Med Chem. 2010;18:7900-10 pubmed publisher

Ryu Y, Jeong H, Kim J, Kim Y, Park J, Kim D, et al. Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition. Bioorg Med Chem. 2010;18:7940-7 pubmed publisher

Wang S, Han X, Li X, Ren D, Wang X, Lou H. Flavonoids from Dracocephalum tanguticum and their cardioprotective effects against doxorubicin-induced toxicity in H9c2 cells. Bioorg Med Chem Lett. 2010;20:6411-5 pubmed publisher

Borbely G, Szabadkai I, Horvath Z, Markó P, Varga Z, Breza N, et al. Small-molecule inhibitors of NADPH oxidase 4. J Med Chem. 2010;53:6758-62 pubmed publisher

Takemura H, Itoh T, Yamamoto K, Sakakibara H, Shimoi K. Selective inhibition of methoxyflavonoids on human CYP1B1 activity. Bioorg Med Chem. 2010;18:6310-5 pubmed publisher

Borges de Melo E, Ataide Martins J, Marinho Jorge T, Friozi M, Castro Ferreira M. Multivariate QSAR study on the antimutagenic activity of flavonoids against 3-NFA on Salmonella typhimurium TA98. Eur J Med Chem. 2010;45:4562-9 pubmed publisher

Gupta A, Saxena S, Saxena M. Integrated ligand and structure based studies of flavonoids as fatty acid biosynthesis inhibitors of Plasmodium falciparum. Bioorg Med Chem Lett. 2010;20:4779-81 pubmed publisher

Liu Y, Nair M. An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds. J Nat Prod. 2010;73:1193-5 pubmed publisher

Wang P, Ownby S, Zhang Z, Yuan W, Li S. Cytotoxicity and inhibition of DNA topoisomerase I of polyhydroxylated triterpenoids and triterpenoid glycosides. Bioorg Med Chem Lett. 2010;20:2790-6 pubmed publisher

Liu G, Xu J, Geng M, Xu R, Hui R, Zhao J, et al. Synthesis of a novel series of diphenolic chromone derivatives as inhibitors of NO production in LPS-activated RAW264.7 macrophages. Bioorg Med Chem. 2010;18:2864-71 pubmed publisher

Tamura S, Yoshihira K, Fujiwara K, Murakami N. New inhibitors for expression of IgE receptor on human mast cell. Bioorg Med Chem Lett. 2010;20:2299-302 pubmed publisher

Nakashima S, Matsuda H, Oda Y, Nakamura S, Xu F, Yoshikawa M. Melanogenesis inhibitors from the desert plant Anastatica hierochuntica in B16 melanoma cells. Bioorg Med Chem. 2010;18:2337-45 pubmed publisher

Bonesi M, Loizzo M, Statti G, Michel S, Tillequin F, Menichini F. The synthesis and angiotensin converting enzyme (ACE) inhibitory activity of chalcones and their pyrazole derivatives. Bioorg Med Chem Lett. 2010;20:1990-3 pubmed publisher

Mercader A, Pomilio A. QSAR study of flavonoids and biflavonoids as influenza H1N1 virus neuraminidase inhibitors. Eur J Med Chem. 2010;45:1724-30 pubmed publisher

Arioka S, Sakagami M, Uematsu R, Yamaguchi H, Togame H, Takemoto H, et al. Potent inhibitor scaffold against Trypanosoma cruzi trans-sialidase. Bioorg Med Chem. 2010;18:1633-40 pubmed publisher

Tian L, Zhang Y, Qu C, Wang Y, Yang C. Phloroglucinol glycosides from the fresh fruits of Eucalyptus maideni. J Nat Prod. 2010;73:160-3 pubmed publisher

Chimenti F, Fioravanti R, Bolasco A, Chimenti P, Secci D, Rossi F, et al. A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors. Bioorg Med Chem. 2010;18:1273-9 pubmed publisher

Yao J, Zhang Q, Min J, He J, Yu Z. Novel enoyl-ACP reductase (FabI) potential inhibitors of Escherichia coli from Chinese medicine monomers. Bioorg Med Chem Lett. 2010;20:56-9 pubmed publisher

Amić D, Lučić B. Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids. Bioorg Med Chem. 2010;18:28-35 pubmed publisher

Katalinić M, Rusak G, Domaćinović Barović J, Sinko G, Jelic D, Antolovic R, et al. Structural aspects of flavonoids as inhibitors of human butyrylcholinesterase. Eur J Med Chem. 2010;45:186-92 pubmed publisher

Kim S, Naveen Kumar C, Kim H, Kim D, Cho J, Jin C, et al. Glucose-containing flavones--their synthesis and antioxidant and neuroprotective activities. Bioorg Med Chem Lett. 2009;19:6009-13 pubmed publisher

Zhou K, Zhao F, Liu Z, Zhuang Y, Chen L, Qiu F. Triterpenoids and flavonoids from celery (Apium graveolens). J Nat Prod. 2009;72:1563-7 pubmed publisher

Jeong H, Ryu Y, Park S, Kim J, Kwon H, Kim J, et al. Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities. Bioorg Med Chem. 2009;17:6816-23 pubmed publisher

Ryu Y, Curtis Long M, Lee J, Ryu H, Kim J, Lee W, et al. Structural characteristics of flavanones and flavones from Cudrania tricuspidata for neuraminidase inhibition. Bioorg Med Chem Lett. 2009;19:4912-5 pubmed publisher

Miyagawa T, Ohtsuki T, Koyano T, Kowithayakorn T, Ishibashi M. Cardenolide glycosides of Thevetia peruviana and triterpenoid saponins of Sapindus emarginatus as TRAIL resistance-overcoming compounds. J Nat Prod. 2009;72:1507-11 pubmed publisher

Nishizaki Y, Ishimoto Y, Hotta Y, Hosoda A, Yoshikawa H, Akamatsu M, et al. Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay. Bioorg Med Chem Lett. 2009;19:4706-10 pubmed publisher

Gonzales A, Orlando R. A Jurkat transcriptional reporter cell line for high-throughput analysis of the nuclear factor-kappaB signaling pathway. N Biotechnol. 2009;26:244-50 pubmed publisher

He Z, Yan J, Song Z, Ye F, Liao X, Peng S, et al. Chemical constituents from the aerial parts of Artemisia minor. J Nat Prod. 2009;72:1198-201 pubmed publisher

Pauff J, Hille R. Inhibition studies of bovine xanthine oxidase by luteolin, silibinin, quercetin, and curcumin. J Nat Prod. 2009;72:725-31 pubmed publisher

López Lázaro M. Distribution and biological activities of the flavonoid luteolin. Mini Rev Med Chem. 2009;9:31-59 pubmed

Lin Y, Shi R, Wang X, Shen H. Luteolin, a flavonoid with potential for cancer prevention and therapy. Curr Cancer Drug Targets. 2008;8:634-46 pubmed

Seelinger G, Merfort I, Wölfle U, Schempp C. Anti-carcinogenic effects of the flavonoid luteolin. Molecules. 2008;13:2628-51 pubmed

Seelinger G, Merfort I, Schempp C. Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin. Planta Med. 2008;74:1667-77 pubmed publisher

Ahmed F, Ohtsuki T, Aida W, Ishibashi M. Tyrosine derivatives isolated from Streptomyces sp. IFM 10937 in a screening program for TRAIL-resistance-overcoming activity. J Nat Prod. 2008;71:1963-6 pubmed publisher

Ying J, Gu S, Yao T. [Research progress on interactions between luteolin (glucosides) and drug-metabolizing enzyme]. Yao Xue Xue Bao. 2008;43:335-42 pubmed

Liu A, Wang H, Lee S, Wang Y, Du G. Structure-activity relationship of flavonoids as influenza virus neuraminidase inhibitors and their in vitro anti-viral activities. Bioorg Med Chem. 2008;16:7141-7 pubmed publisher

Lo Piparo E, Scheib H, Frei N, Williamson G, Grigorov M, Chou C. Flavonoids for controlling starch digestion: structural requirements for inhibiting human alpha-amylase. J Med Chem. 2008;51:3555-61 pubmed publisher

Qiu L, Zhao F, Jiang Z, Chen L, Zhao Q, Liu H, et al. Steroids and flavonoids from Physalis alkekengi var. franchetii and their inhibitory effects on nitric oxide production. J Nat Prod. 2008;71:642-6 pubmed publisher

Lv P, Li H, Xue J, Shi L, Zhu H. Synthesis and biological evaluation of novel luteolin derivatives as antibacterial agents. Eur J Med Chem. 2009;44:908-14 pubmed publisher

Yoo N, Jang D, Yoo J, Lee Y, Kim Y, Cho J, et al. Erigeroflavanone, a flavanone derivative from the flowers of Erigeron annuus with protein glycation and aldose reductase inhibitory activity. J Nat Prod. 2008;71:713-5 pubmed publisher

Takasawa R, Takahashi S, Saeki K, Sunaga S, Yoshimori A, Tanuma S. Structure-activity relationship of human GLO I inhibitory natural flavonoids and their growth inhibitory effects. Bioorg Med Chem. 2008;16:3969-75 pubmed publisher

Theoharides T, Kempuraj D, Iliopoulou B. Mast cells, T cells, and inhibition by luteolin: implications for the pathogenesis and treatment of multiple sclerosis. Adv Exp Med Biol. 2007;601:423-30 pubmed

Holder S, Lilly M, Brown M. Comparative molecular field analysis of flavonoid inhibitors of the PIM-1 kinase. Bioorg Med Chem. 2007;15:6463-73 pubmed

Gomes A, Fernandes E, Silva A, Santos C, Pinto D, Cavaleiro J, et al. 2-Styrylchromones: novel strong scavengers of reactive oxygen and nitrogen species. Bioorg Med Chem. 2007;15:6027-36 pubmed

Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed

López Lázaro M, Willmore E, Austin C. Cells lacking DNA topoisomerase II beta are resistant to genistein. J Nat Prod. 2007;70:763-7 pubmed

Lee J, Park T, Jeong S, Kim K, Hong C. 3-Hydroxychromones as cyclin-dependent kinase inhibitors: synthesis and biological evaluation. Bioorg Med Chem Lett. 2007;17:1284-7 pubmed

Lupu R, Menendez J. Pharmacological inhibitors of Fatty Acid Synthase (FASN)--catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents?. Curr Pharm Biotechnol. 2006;7:483-93 pubmed

Khlebnikov A, Schepetkin I, Domina N, Kirpotina L, Quinn M. Improved quantitative structure-activity relationship models to predict antioxidant activity of flavonoids in chemical, enzymatic, and cellular systems. Bioorg Med Chem. 2007;15:1749-70 pubmed

Matsuda H, Yoshida K, Miyagawa K, Asao Y, Takayama S, Nakashima S, et al. Rotenoids and flavonoids with anti-invasion of HT1080, anti-proliferation of U937, and differentiation-inducing activity in HL-60 from Erycibe expansa. Bioorg Med Chem. 2007;15:1539-46 pubmed

Zhang F, Shen H, Zhu X. [Research progress on anti-tumor effects of luteolin]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2006;35:573-8 pubmed

Sathiamoorthy B, Gupta P, Kumar M, Chaturvedi A, Shukla P, Maurya R. New antifungal flavonoid glycoside from Vitex negundo. Bioorg Med Chem Lett. 2007;17:239-42 pubmed

Na M, Jang J, Min B, Lee S, Lee M, Kim B, et al. Fatty acid synthase inhibitory activity of acylphloroglucinols isolated from Dryopteris crassirhizoma. Bioorg Med Chem Lett. 2006;16:4738-42 pubmed

Tasdemir D, Lack G, Brun R, Rüedi P, Scapozza L, Perozzo R. Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids. J Med Chem. 2006;49:3345-53 pubmed

Rao P, Chen Q, Knaus E. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases. J Med Chem. 2006;49:1668-83 pubmed

McArdle B, Campitelli M, Quinn R. A common protein fold topology shared by flavonoid biosynthetic enzymes and therapeutic targets. J Nat Prod. 2006;69:14-7 pubmed

Bullock A, Debreczeni J, Fedorov O, Nelson A, Marsden B, Knapp S. Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase. J Med Chem. 2005;48:7604-14 pubmed

Rao P, Chen Q, Knaus E. Synthesis and biological evaluation of 1,3-diphenylprop-2-yn-1-ones as dual inhibitors of cyclooxygenases and lipoxygenases. Bioorg Med Chem Lett. 2005;15:4842-5 pubmed

Kandaswami C, Kanadaswami C, Lee L, Lee P, Hwang J, Ke F, et al. The antitumor activities of flavonoids. In Vivo. 2005;19:895-909 pubmed

Larsson J, Gottfries J, Bohlin L, Backlund A. Expanding the ChemGPS chemical space with natural products. J Nat Prod. 2005;68:985-91 pubmed

Chang F, Hayashi K, Chua N, Kamio S, Huang Z, Nozaki H, et al. The transgenic Arabidopsis plant system, pER8-GFP, as a powerful tool in searching for natural product estrogen-agonists/antagonists. J Nat Prod. 2005;68:971-3 pubmed

Shimoi K, Masuda S, Furugori M, Esaki S, Kinae N. Radioprotective effect of antioxidative flavonoids in gamma-ray irradiated mice. Carcinogenesis. 1994;15:2669-72 pubmed

Bors W, Michel C, Saran M. Flavonoid antioxidants: rate constants for reactions with oxygen radicals. Methods Enzymol. 1994;234:420-9 pubmed