This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Lysostaphin from Staphylococcus simulans
catalog :
L9043
citations: 44
Reference
Nithya V, Rathinam S, Siva Ganesa Karthikeyan R, Lalitha P. A ten year study of prevalence, antimicrobial susceptibility pattern, and genotypic characterization of Methicillin resistant Staphylococcus aureus causing ocular infections in a tertiary eye care hospital in South India. Infect Genet Evol. 2019;69:203-210 pubmed publisher
Hu Y, Yang H, Wang J, Zhang Y, Yu J, Wei H. Comparison between a chimeric lysin ClyH and other enzymes for extracting DNA to detect methicillin resistant Staphylococcus aureus by quantitative PCR. World J Microbiol Biotechnol. 2016;32:1 pubmed publisher
Utter B, Deutsch D, Schuch R, Winer B, Verratti K, Bishop Lilly K, et al. Beyond the chromosome: the prevalence of unique extra-chromosomal bacteriophages with integrated virulence genes in pathogenic Staphylococcus aureus. PLoS ONE. 2014;9:e100502 pubmed publisher
Mohamed M, Hamed M, Panitch A, Seleem M. Targeting methicillin-resistant Staphylococcus aureus with short salt-resistant synthetic peptides. Antimicrob Agents Chemother. 2014;58:4113-22 pubmed publisher
Kumar A, Khan I, Sharma P, K S, Ella K. Evaluation of activity of recombinant lysostaphin against isolates of meticillin-resistant Staphylococcus aureus from Indian hospitals. J Med Microbiol. 2014;63:763-766 pubmed publisher
Desbois A, Sattar A, Graham S, Warn P, Coote P. MRSA decolonization of cotton rat nares by a combination treatment comprising lysostaphin and the antimicrobial peptide ranalexin. J Antimicrob Chemother. 2013;68:2569-75 pubmed publisher
Huang C, Hsu J, Chung P, Cheng W, Jiang Y, Ju Y. Site-specific N-glycosylation of caprine lysostaphin restricts its bacteriolytic activity toward Staphylococcus aureus. Anim Biotechnol. 2013;24:129-47 pubmed publisher
Lu H, Gu M, Huang Q, Huang J, Lu W, Lu H, et al. Hydrogen/deuterium exchange mass spectrometry and site-directed disulfide cross-linking suggest an important dynamic interface between the two lysostaphin domains. Antimicrob Agents Chemother. 2013;57:1872-81 pubmed publisher
Okumura A, Suzuki T, Miyatake H, Okabe T, Hashimoto Y, Miyakawa T, et al. Leukocyte cell-derived chemotaxin 2 is a zinc-binding protein. FEBS Lett. 2013;587:404-9 pubmed publisher
Chen Y, Simmonds R, Young J, Timkovich R. Solution structure of the recombinant target recognition domain of zoocin A. Proteins. 2013;81:722-7 pubmed publisher
Potapova I, Eglin D, Laschke M, Bischoff M, Richards R, Moriarty T. Two-step labeling of Staphylococcus aureus with Lysostaphin-Azide and DIBO-Alexa using click chemistry. J Microbiol Methods. 2013;92:90-8 pubmed publisher
Levinger O, Bikels Goshen T, Landau E, Fichman M, Shapira R. Epigallocatechin gallate induces upregulation of the two-component VraSR system by evoking a cell wall stress response in Staphylococcus aureus. Appl Environ Microbiol. 2012;78:7954-9 pubmed publisher
Houry A, Gohar M, Deschamps J, Tischenko E, Aymerich S, Gruss A, et al. Bacterial swimmers that infiltrate and take over the biofilm matrix. Proc Natl Acad Sci U S A. 2012;109:13088-93 pubmed publisher
Sabala I, Jonsson I, Tarkowski A, Bochtler M. Anti-staphylococcal activities of lysostaphin and LytM catalytic domain. BMC Microbiol. 2012;12:97 pubmed publisher
Vipra A, Desai S, Roy P, Patil R, Raj J, Narasimhaswamy N, et al. Antistaphylococcal activity of bacteriophage derived chimeric protein P128. BMC Microbiol. 2012;12:41 pubmed publisher
Wu H, Fang W, Yuan J, Peng H, Zhang X, Wang Y, et al. [Site-directed mutagenesis and sulfhydryl PEGylation of lysostaphin]. Sheng Wu Gong Cheng Xue Bao. 2011;27:1623-30 pubmed
Schmelcher M, Powell A, Becker S, Camp M, Donovan D. Chimeric phage lysins act synergistically with lysostaphin to kill mastitis-causing Staphylococcus aureus in murine mammary glands. Appl Environ Microbiol. 2012;78:2297-305 pubmed publisher
Satishkumar R, Vertegel A. Antibody-directed targeting of lysostaphin adsorbed onto polylactide nanoparticles increases its antimicrobial activity against S. aureus in vitro. Nanotechnology. 2011;22:505103 pubmed publisher
Liu H, Gao Y, Yu L, Jones R, Elkins C, Hart M. Inhibition of Staphylococcus aureus by lysostaphin-expressing Lactobacillus plantarum WCFS1 in a modified genital tract secretion medium. Appl Environ Microbiol. 2011;77:8500-8 pubmed publisher
Miao J, Pangule R, Paskaleva E, Hwang E, Kane R, Linhardt R, et al. Lysostaphin-functionalized cellulose fibers with antistaphylococcal activity for wound healing applications. Biomaterials. 2011;32:9557-67 pubmed publisher
Belyansky I, Tsirline V, Montero P, Satishkumar R, Martin T, Lincourt A, et al. Lysostaphin-coated mesh prevents staphylococcal infection and significantly improves survival in a contaminated surgical field. Am Surg. 2011;77:1025-31 pubmed
Lawson T, Connally R, Vemulpad S, Piper J. Optimization of a two-step permeabilization fluorescence in situ hybridization (FISH) assay for the detection of Staphylococcus aureus. J Clin Lab Anal. 2011;25:359-65 pubmed publisher
Patel D, Husain M, Vidaillac C, Steed M, Rybak M, Seo S, et al. Mechanisms of in-vitro-selected daptomycin-non-susceptibility in Staphylococcus aureus. Int J Antimicrob Agents. 2011;38:442-6 pubmed publisher
Fenton M, Ross R, McAuliffe O, O Mahony J, Coffey A. Characterization of the staphylococcal bacteriophage lysin CHAP(K). J Appl Microbiol. 2011;111:1025-35 pubmed publisher
Yurko Y, McDeavitt K, Kumar R, Martin T, Prabhu A, Lincourt A, et al. Antibacterial mesh: a novel technique involving naturally occurring cellular proteins. Surg Innov. 2012;19:20-6 pubmed publisher
Satishkumar R, Sankar S, Yurko Y, Lincourt A, Shipp J, Heniford B, et al. Evaluation of the antimicrobial activity of lysostaphin-coated hernia repair meshes. Antimicrob Agents Chemother. 2011;55:4379-85 pubmed publisher
Belyansky I, Tsirline V, Martin T, Klima D, Heath J, Lincourt A, et al. The addition of lysostaphin dramatically improves survival, protects porcine biomesh from infection, and improves graft tensile shear strength. J Surg Res. 2011;171:409-15 pubmed publisher
Aguinaga A, Francés M, del Pozo J, Alonso M, Serrera A, Lasa I, et al. Lysostaphin and clarithromycin: a promising combination for the eradication of Staphylococcus aureus biofilms. Int J Antimicrob Agents. 2011;37:585-7 pubmed publisher
Lawson T, Connally R, Iredell J, Vemulpad S, Piper J. Detection of Staphylococcus aureus with a fluorescence in situ hybridization that does not require lysostaphin. J Clin Lab Anal. 2011;25:142-7 pubmed publisher
Desbois A, Coote P. Bactericidal synergy of lysostaphin in combination with antimicrobial peptides. Eur J Clin Microbiol Infect Dis. 2011;30:1015-21 pubmed publisher
Jonsson I, Juuti J, Francois P, AlMajidi R, Pietiäinen M, Girard M, et al. Inactivation of the Ecs ABC transporter of Staphylococcus aureus attenuates virulence by altering composition and function of bacterial wall. PLoS ONE. 2010;5:e14209 pubmed publisher
Feizabadi M, Ghodousi A, Nomanpour B, Omrani M, Shahcheraghi F. Development of a modified DNA extraction method for pulsed-field gel electrophoresis analysis of Staphylococcus aureus and enterococci without using lysostaphin. J Microbiol Methods. 2011;84:144-6 pubmed publisher
Gargis S, Heath H, LeBlanc P, Dekker L, Simmonds R, Sloan G. Inhibition of the activity of both domains of lysostaphin through peptidoglycan modification by the lysostaphin immunity protein. Appl Environ Microbiol. 2010;76:6944-6 pubmed publisher
Cui F, Li G, Huang J, Zhang J, Lu M, Lu W, et al. Extension of nasal anti-Staphylococcus aureus efficacy of lysostaphin by its incorporation into a chitosan-o/w cream. Drug Deliv. 2010;17:617-23 pubmed publisher
Balibar C, Shen X, Tao J. The mevalonate pathway of Staphylococcus aureus. J Bacteriol. 2009;191:851-61 pubmed publisher
Francius G, Domenech O, Mingeot Leclercq M, Dufrêne Y. Direct observation of Staphylococcus aureus cell wall digestion by lysostaphin. J Bacteriol. 2008;190:7904-9 pubmed publisher
Nuryastuti T, van der Mei H, Busscher H, Kuijer R, Aman A, Krom B. recA mediated spontaneous deletions of the icaADBC operon of clinical Staphylococcus epidermidis isolates: a new mechanism of phenotypic variations. Antonie Van Leeuwenhoek. 2008;94:317-28 pubmed publisher
Zander J, Besier S, Saum S, Dehghani F, Loitsch S, Brade V, et al. Influence of dTMP on the phenotypic appearance and intracellular persistence of Staphylococcus aureus. Infect Immun. 2008;76:1333-9 pubmed
Ramadurai L, Jayaswal R. Molecular cloning, sequencing, and expression of lytM, a unique autolytic gene of Staphylococcus aureus. J Bacteriol. 1997;179:3625-31 pubmed
Thumm G, Gotz F. Studies on prolysostaphin processing and characterization of the lysostaphin immunity factor (Lif) of Staphylococcus simulans biovar staphylolyticus. Mol Microbiol. 1997;23:1251-65 pubmed
Baba T, Schneewind O. Target cell specificity of a bacteriocin molecule: a C-terminal signal directs lysostaphin to the cell wall of Staphylococcus aureus. EMBO J. 1996;15:4789-97 pubmed
Dehart H, Heath H, Heath L, Leblanc P, Sloan G. The lysostaphin endopeptidase resistance gene (epr) specifies modification of peptidoglycan cross bridges in Staphylococcus simulans and Staphylococcus aureus. Appl Environ Microbiol. 1995;61:1475-9 pubmed
Recsei P, Gruss A, Novick R. Cloning, sequence, and expression of the lysostaphin gene from Staphylococcus simulans. Proc Natl Acad Sci U S A. 1987;84:1127-31 pubmed
Wang X, Wilkinson B, Jayaswal R. Sequence analysis of a Staphylococcus aureus gene encoding a peptidoglycan hydrolase activity. Gene. 1991;102:105-9 pubmed
product information
Catalog Number :
L9043
Product Name :
Lysostaphin from Staphylococcus simulans
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
recombinant, expressed in E. coli, lyophilized powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA