This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Latrunculin A
catalog :
L5163
citations: 293
Reference
Wu N, Cernysiov V, Davidson D, Song H, Tang J, Luo S, et al. Critical Role of Lipid Scramblase TMEM16F in Phosphatidylserine Exposure and Repair of Plasma Membrane after Pore Formation. Cell Rep. 2020;30:1129-1140.e5 pubmed publisher
Woida P, Satchell K. The Vibrio cholerae MARTX toxin silences the inflammatory response to cytoskeletal damage before inducing actin cytoskeleton collapse. Sci Signal. 2020;13: pubmed publisher
York Andersen A, Hu Q, Wood B, Wolfner M, Weil T. A calcium-mediated actin redistribution at egg activation in Drosophila. Mol Reprod Dev. 2020;87:293-304 pubmed publisher
Brzeska H, Gonzalez J, Korn E, Titus M. Basic-hydrophobic sites are localized in conserved positions inside and outside of PH domains and affect localization of Dictyostelium myosin 1s. Mol Biol Cell. 2020;31:101-117 pubmed publisher
Lucero D, Islam P, Freeman L, Jin X, Pryor M, Tang J, et al. Interleukin 10 promotes macrophage uptake of HDL and LDL by stimulating fluid-phase endocytosis. Biochim Biophys Acta Mol Cell Biol Lipids. 2020;1865:158537 pubmed publisher
Schuster M, Guiu Aragonés C, Steinberg G. Class V chitin synthase and β(1,3)-glucan synthase co-travel in the same vesicle in Zymoseptoria tritici. Fungal Genet Biol. 2020;135:103286 pubmed publisher
Filomena M, Yamamoto D, Caremani M, Kadarla V, Mastrototaro G, Serio S, et al. Myopalladin promotes muscle growth through modulation of the serum response factor pathway. J Cachexia Sarcopenia Muscle. 2020;11:169-194 pubmed publisher
Gómez Elías M, Fissore R, Cuasnicu P, Cohen D. Compensatory endocytosis occurs after cortical granule exocytosis in mouse eggs. J Cell Physiol. 2020;235:4351-4360 pubmed publisher
Limatola N, Vasilev F, Santella L, Chun J. Nicotine Induces Polyspermy in Sea Urchin Eggs through a Non-Cholinergic Pathway Modulating Actin Dynamics. Cells. 2019;9: pubmed publisher
Valenzuela J, Perez F. Localized Intercellular Transfer of Ephrin-As by Trans-endocytosis Enables Long-Term Signaling. Dev Cell. 2019;: pubmed publisher
Song H, Zhang J, He W, Wang P, Wang F. Activation of Cofilin Increases Intestinal Permeability via Depolymerization of F-Actin During Hypoxia in vitro. Front Physiol. 2019;10:1455 pubmed publisher
Roper S, Wasim L, Malinova D, Way M, Cox S, Tolar P. B cells extract antigens at Arp2/3-generated actin foci interspersed with linear filaments. elife. 2019;8: pubmed publisher
Caragine C, Haley S, Zidovska A. Nucleolar dynamics and interactions with nucleoplasm in living cells. elife. 2019;8: pubmed publisher
Piriya Ananda Babu L, Wang H, Eguchi K, Guillaud L, Takahashi T. Microtubule and Actin Differentially Regulate Synaptic Vesicle Cycling to Maintain High-frequency Neurotransmission. J Neurosci. 2019;: pubmed publisher
Hercyk B, Rich Robinson J, Mitoubsi A, Harrell M, Das M. A novel interplay between GEFs orchestrates Cdc42 activity during cell polarity and cytokinesis in fission yeast. J Cell Sci. 2019;132: pubmed publisher
Sundqvist M, Christenson K, Gabl M, Holdfeldt A, Jennbacken K, Møller T, et al. Staphylococcus aureus-Derived PSMα Peptides Activate Neutrophil FPR2 but Lack the Ability to Mediate β-Arrestin Recruitment and Chemotaxis. J Immunol. 2019;203:3349-3360 pubmed publisher
Tsao L, Crosby E, Trotter T, Agarwal P, Hwang B, Acharya C, et al. CD47 blockade augmentation of trastuzumab antitumor efficacy dependent on antibody-dependent cellular phagocytosis. JCI Insight. 2019;4: pubmed publisher
Dupraz S, Hilton B, Husch A, Santos T, Coles C, Stern S, et al. RhoA Controls Axon Extension Independent of Specification in the Developing Brain. Curr Biol. 2019;29:3874-3886.e9 pubmed publisher
Kim J, Schalk J, Koss W, Gremminger R, Taxier L, Gross K, et al. Dorsal Hippocampal Actin Polymerization Is Necessary for Activation of G-Protein-Coupled Estrogen Receptor (GPER) to Increase CA1 Dendritic Spine Density and Enhance Memory Consolidation. J Neurosci. 2019;39:9598-9610 pubmed publisher
Huang J, Li C, Fan F, Liu N, Boadi F, Shen X, et al. Methyl-Beta-Cyclodextrin-Induced Macropinocytosis Results in Increased Infection of Sf21 Cells by Bombyx Mori Nucleopolyhedrovirus. Viruses. 2019;11: pubmed publisher
Ji Y, Li J, Wei Y, Gao W, Fu X, Wang Y. Substrate stiffness affects the immunosuppressive and trophic function of hMSCs via modulating cytoskeletal polymerization and tension. Biomater Sci. 2019;7:5292-5300 pubmed publisher
Faust J, Millis B, Tyska M. Profilin-Mediated Actin Allocation Regulates the Growth of Epithelial Microvilli. Curr Biol. 2019;29:3457-3465.e3 pubmed publisher
Bryce N, Failes T, Stehn J, Baker K, Zahler S, Arzhaeva Y, et al. High-Content Imaging of Unbiased Chemical Perturbations Reveals that the Phenotypic Plasticity of the Actin Cytoskeleton Is Constrained. Cell Syst. 2019;9:496-507.e5 pubmed publisher
Kirmiz M, Gillies T, Dickson E, Trimmer J. Neuronal ER-plasma membrane junctions organized by Kv2-VAP pairing recruit Nir proteins and affect phosphoinositide homeostasis. J Biol Chem. 2019;294:17735-17757 pubmed publisher
Shlevkov E, Basu H, Bray M, Sun Z, Wei W, Apaydin K, et al. A High-Content Screen Identifies TPP1 and Aurora B as Regulators of Axonal Mitochondrial Transport. Cell Rep. 2019;28:3224-3237.e5 pubmed publisher
Duarte S, Viedma Poyatos Á, Navarro Carrasco E, Martinez A, Pajares M, Perez Sala D. Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division. Nat Commun. 2019;10:4200 pubmed publisher
Zhou R, Han B, Xia C, Zhuang X. Membrane-associated periodic skeleton is a signaling platform for RTK transactivation in neurons. Science. 2019;365:929-934 pubmed publisher
Pinto C, Khandekar A, Bhavna R, Kiesel P, Pigino G, Sonawane M. Microridges are apical epithelial projections formed of F-actin networks that organize the glycan layer. Sci Rep. 2019;9:12191 pubmed publisher
Stavreva D, Garcia D, Fettweis G, Gudla P, Zaki G, Soni V, et al. Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility. Mol Cell. 2019;75:1161-1177.e11 pubmed publisher
MacQuarrie C, Mangione M, Carroll R, James M, Gould K, Sirotkin V. The S. pombe adaptor protein Bbc1 regulates localization of Wsp1 and Vrp1 during endocytic actin patch assembly. J Cell Sci. 2019;132: pubmed publisher
Xia S, Lim Y, Zhang Z, Wang Y, Zhang S, Lim C, et al. Nanoscale Architecture of the Cortical Actin Cytoskeleton in Embryonic Stem Cells. Cell Rep. 2019;28:1251-1267.e7 pubmed publisher
Fujimoto K, Tanaka M, Rana A, Jahan M, Itoh G, Tsujioka M, et al. Dynamin-Like Protein B of Dictyostelium Contributes to Cytokinesis Cooperatively with Other Dynamins. Cells. 2019;8: pubmed publisher
Letizia A, He D, Astigarraga S, Colombelli J, Hatini V, Llimargas M, et al. Sidekick Is a Key Component of Tricellular Adherens Junctions that Acts to Resolve Cell Rearrangements. Dev Cell. 2019;50:313-326.e5 pubmed publisher
Witzel P, Götz M, Lanoiselée Y, Franosch T, Grebenkov D, Heinrich D. Heterogeneities Shape Passive Intracellular Transport. Biophys J. 2019;117:203-213 pubmed publisher
Zhang C, Chen F, Liu X, Han X, Hu Y, Su X, et al. Gliotoxin Induces Cofilin Phosphorylation to Promote Actin Cytoskeleton Dynamics and Internalization of Aspergillus fumigatus Into Type II Human Pneumocyte Cells. Front Microbiol. 2019;10:1345 pubmed publisher
Heckmann B, Teubner B, Tummers B, Boada Romero E, Harris L, Yang M, et al. LC3-Associated Endocytosis Facilitates β-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer's Disease. Cell. 2019;: pubmed publisher
Zhang S, Reinhard B. Characterizing Large-Scale Receptor Clustering on the Single Cell Level: A Comparative Plasmon Coupling and Fluorescence Superresolution Microscopy Study. J Phys Chem B. 2019;123:5494-5505 pubmed publisher
Mukaiyama M, Yamasaki Y, Usui T, Nagumo Y. Transient receptor potential V4 channel stimulation induces reversible epithelial cell permeability in MDCK cell monolayers. FEBS Lett. 2019;593:2250-2260 pubmed publisher
Saez J, Diaz J, Ibáñez J, Bozo J, Cabrera Reyes F, Alamo M, et al. The exocyst controls lysosome secretion and antigen extraction at the immune synapse of B cells. J Cell Biol. 2019;: pubmed publisher
Möckel M, Rahn E, de la Cruz N, Wirtz L, van Lent J, Pijlman G, et al. Herpes Simplex Virus 1 can enter dynamin 1 and 2 double knockout fibroblasts. J Virol. 2019;: pubmed publisher
Chen S, Liu Y, Zhou Y, Zhao P, Ren H, Xiao M, et al. Endophilin-A2-mediated endocytic pathway is critical for enterovirus 71 entry into caco-2 cells. Emerg Microbes Infect. 2019;8:773-786 pubmed publisher
Riggi M, Bourgoint C, Macchione M, Matile S, Loewith R, Roux A. TORC2 controls endocytosis through plasma membrane tension. J Cell Biol. 2019;: pubmed publisher
Shahin Shamsabadi A, Selvaganapathy P. A rapid biofabrication technique for self-assembled collagen-based multicellular and heterogeneous 3D tissue constructs. Acta Biomater. 2019;92:172-183 pubmed publisher
Shurer C, Kuo J, Roberts L, Gandhi J, Colville M, Enoki T, et al. Physical Principles of Membrane Shape Regulation by the Glycocalyx. Cell. 2019;: pubmed publisher
Obashi K, Matsuda A, Inoue Y, Okabe S. Precise Temporal Regulation of Molecular Diffusion within Dendritic Spines by Actin Polymers during Structural Plasticity. Cell Rep. 2019;27:1503-1515.e8 pubmed publisher
Li J, Sekine Aizawa Y, Ebrahimi S, Tanaka S, Okabe S. Tumor suppressor protein CYLD regulates morphogenesis of dendrites and spines. Eur J Neurosci. 2019;: pubmed publisher
Takahashi N, Nobusue H, Shimizu T, Sugihara E, Yamaguchi Iwai S, Onishi N, et al. ROCK Inhibition Induces Terminal Adipocyte Differentiation and Suppresses Tumorigenesis in Chemoresistant Osteosarcoma Cells. Cancer Res. 2019;79:3088-3099 pubmed publisher
Hu J, Cheng S, Wang H, Li X, Liu S, Wu M, et al. Distinct roles of two myosins in C. elegans spermatid differentiation. PLoS Biol. 2019;17:e3000211 pubmed publisher
Rylaarsdam L, Johnecheck G, Looyenga B, Louters L. GLUT1 is associated with sphingolipid-organized, cholesterol-independent domains in L929 mouse fibroblast cells. Biochimie. 2019;162:88-96 pubmed publisher
Alenquer M, Vale Costa S, Etibor T, Ferreira F, Sousa A, Amorim M. Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites. Nat Commun. 2019;10:1629 pubmed publisher
A M, Fung T, Kettenbach A, Chakrabarti R, Higgs H. A complex containing lysine-acetylated actin inhibits the formin INF2. Nat Cell Biol. 2019;21:592-602 pubmed publisher
Efremov Y, Velay Lizancos M, Weaver C, Athamneh A, Zavattieri P, Suter D, et al. Anisotropy vs isotropy in living cell indentation with AFM. Sci Rep. 2019;9:5757 pubmed publisher
Malandrino A, Trepat X, Kamm R, Mak M. Dynamic filopodial forces induce accumulation, damage, and plastic remodeling of 3D extracellular matrices. PLoS Comput Biol. 2019;15:e1006684 pubmed publisher
Lim S, Hermance N, Mudianto T, Mustaly H, Mauricio I, Vittoria M, et al. Identification of the kinase STK25 as an upstream activator of LATS signaling. Nat Commun. 2019;10:1547 pubmed publisher
Tsujioka M, Uyeda T, Iwadate Y, Patel H, Shibata K, Yumoto T, et al. Actin-binding domains mediate the distinct distribution of two Dictyostelium Talins through different affinities to specific subsets of actin filaments during directed cell migration. PLoS ONE. 2019;14:e0214736 pubmed publisher
Van Itallie C, Lidman K, Tietgens A, Anderson J. Newly synthesized claudins but not occludin are added to the basal side of the tight junction. Mol Biol Cell. 2019;30:1406-1424 pubmed publisher
Umeki N, Shibata K, Noguchi T, Hirose K, Sako Y, Uyeda T. K336I mutant actin alters the structure of neighbouring protomers in filaments and reduces affinity for actin-binding proteins. Sci Rep. 2019;9:5353 pubmed publisher
Griesche N, Sanchez G, Hermans C, Idevall Hagren O. Cortical mitochondria regulate insulin secretion by local Ca2+ buffering in rodent beta cells. J Cell Sci. 2019;132: pubmed publisher
Hamieh M, Dobrin A, Cabriolu A, van der Stegen S, Giavridis T, Mansilla Soto J, et al. CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape. Nature. 2019;568:112-116 pubmed publisher
Bertolio R, Napoletano F, Mano M, Maurer Stroh S, Fantuz M, Zannini A, et al. Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism. Nat Commun. 2019;10:1326 pubmed publisher
Barger S, Reilly N, Shutova M, Li Q, Maiuri P, Heddleston J, et al. Membrane-cytoskeletal crosstalk mediated by myosin-I regulates adhesion turnover during phagocytosis. Nat Commun. 2019;10:1249 pubmed publisher
Capmany A, Yoshimura A, Kerdous R, Caorsi V, Lescure A, del Nery E, et al. MYO1C stabilizes actin and facilitates the arrival of transport carriers at the Golgi complex. J Cell Sci. 2019;132: pubmed publisher
Romero L, Massey A, Mata Daboin A, Sierra Valdez F, Chauhan S, Cordero Morales J, et al. Dietary fatty acids fine-tune Piezo1 mechanical response. Nat Commun. 2019;10:1200 pubmed publisher
Fujii Y, Ochi Y, Tuchiya M, Kajita M, Fujita Y, Ishimoto Y, et al. Spontaneous Spatial Correlation of Elastic Modulus in Jammed Epithelial Monolayers Observed by AFM. Biophys J. 2019;116:1152-1158 pubmed publisher
Feng Y, Zhu R, Shen J, Wu J, Lu W, Zhang J, et al. Human Bone Marrow Mesenchymal Stem Cells Rescue Endothelial Cells Experiencing Chemotherapy Stress by Mitochondrial Transfer via Tunnelling Nanotubes. Stem Cells Dev. 2019;: pubmed publisher
Ho W, Freem L, Zhao D, Painter K, Woolley T, Gaffney E, et al. Feather arrays are patterned by interacting signalling and cell density waves. PLoS Biol. 2019;17:e3000132 pubmed publisher
Jalal S, Shi S, Acharya V, Huang R, Viasnoff V, Bershadsky A, et al. Actin cytoskeleton self-organization in single epithelial cells and fibroblasts under isotropic confinement. J Cell Sci. 2019;132: pubmed publisher
Rampérez A, Bartolomé Martín D, Garcia Pascual A, Sánchez Prieto J, Torres M. Photoconversion of FM1-43 Reveals Differences in Synaptic Vesicle Recycling and Sensitivity to Pharmacological Disruption of Actin Dynamics in Individual Synapses. ACS Chem Neurosci. 2019;10:2045-2059 pubmed publisher
Fukushima S, Matsuoka S, Ueda M. Excitable dynamics of Ras triggers spontaneous symmetry breaking of PIP3 signaling in motile cells. J Cell Sci. 2019;132: pubmed publisher
Tay Y, Leda M, Spanos C, Rappsilber J, Goryachev A, Sawin K. Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex. Cell Rep. 2019;26:1654-1667.e7 pubmed publisher
Narita K, Suzuki N, Himi N, Murayama T, Nakagawa T, Okabe N, et al. Effects of intravesicular loading of a Ca2+ chelator and depolymerization of actin fibers on neurotransmitter release in frog motor nerve terminals. Eur J Neurosci. 2019;50:1700-1711 pubmed publisher
Moorthy B, Sharma A, Boettner D, Wilson T, Lemmon S. Identification of Suppressor of Clathrin Deficiency-1 (SCD1) and Its Connection to Clathrin-Mediated Endocytosis in Saccharomyces cerevisiae. G3 (Bethesda). 2019;9:867-877 pubmed publisher
Tutwiler V, Peshkova A, Le Minh G, Zaitsev S, Litvinov R, Cines D, et al. Blood clot contraction differentially modulates internal and external fibrinolysis. J Thromb Haemost. 2019;17:361-370 pubmed publisher
Kothari P, Srivastava V, Aggarwal V, Tchernyshyov I, Van Eyk J, Ha T, et al. Contractility kits promote assembly of the mechanoresponsive cytoskeletal network. J Cell Sci. 2019;132: pubmed publisher
Makhoul C, Gosavi P, Duffield R, Delbridge B, Williamson N, Gleeson P. Intersectin-1 interacts with the golgin GCC88 to couple the actin network and Golgi architecture. Mol Biol Cell. 2019;30:370-386 pubmed publisher
Khasa R, Vaidya A, Vrati S, Kalia M. Membrane trafficking RNA interference screen identifies a crucial role of the clathrin endocytic pathway and ARP2/3 complex for Japanese encephalitis virus infection in HeLa cells. J Gen Virol. 2019;100:176-186 pubmed publisher
Gemperle J, Dibus M, Koudelková L, Rosel D, Brabek J. The interaction of p130Cas with PKN3 promotes malignant growth. Mol Oncol. 2019;13:264-289 pubmed publisher
Fenix A, Neininger A, Taneja N, Hyde K, Visetsouk M, Garde R, et al. Muscle-specific stress fibers give rise to sarcomeres in cardiomyocytes. elife. 2018;7: pubmed publisher
Shah J, Rouaud F, Guerrera D, Vasileva E, Popov L, Kelley W, et al. A Dock-and-Lock Mechanism Clusters ADAM10 at Cell-Cell Junctions to Promote α-Toxin Cytotoxicity. Cell Rep. 2018;25:2132-2147.e7 pubmed publisher
Tikiyani V, Li L, Sharma P, Liu H, Hu Z, Babu K. Wnt Secretion Is Regulated by the Tetraspan Protein HIC-1 through Its Interaction with Neurabin/NAB-1. Cell Rep. 2018;25:1856-1871.e6 pubmed publisher
Priti A, Ong H, Toyama Y, Padmanabhan A, Dasgupta S, Krajnc M, et al. Syncytial germline architecture is actively maintained by contraction of an internal actomyosin corset. Nat Commun. 2018;9:4694 pubmed publisher
Matsuoka S, Ueda M. Mutual inhibition between PTEN and PIP3 generates bistability for polarity in motile cells. Nat Commun. 2018;9:4481 pubmed publisher
Divakaruni S, Van Dyke A, Chandra R, Legates T, Contreras M, Dharmasri P, et al. Long-Term Potentiation Requires a Rapid Burst of Dendritic Mitochondrial Fission during Induction. Neuron. 2018;100:860-875.e7 pubmed publisher
Haupt A, Ershov D, Minc N. A Positive Feedback between Growth and Polarity Provides Directional Persistency and Flexibility to the Process of Tip Growth. Curr Biol. 2018;28:3342-3351.e3 pubmed publisher
Neubert E, Meyer D, Rocca F, Gunay G, Kwaczala Tessmann A, Grandke J, et al. Chromatin swelling drives neutrophil extracellular trap release. Nat Commun. 2018;9:3767 pubmed publisher
Takahashi T, Okeyo K, Ueda J, Yamagata K, Washizu M, Oana H. A microfluidic device for isolating intact chromosomes from single mammalian cells and probing their folding stability by controlling solution conditions. Sci Rep. 2018;8:13684 pubmed publisher
Kulkarni S, Griffin J, Date P, Liem K, Khokha M. WDR5 Stabilizes Actin Architecture to Promote Multiciliated Cell Formation. Dev Cell. 2018;46:595-610.e3 pubmed publisher
Kim H, Mun Y, Lee K, Park Y, Park J, Park J, et al. T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells. Nat Commun. 2018;9:3630 pubmed publisher
Subramanian B, Moissoglu K, Parent C. The LTB4-BLT1 axis regulates the polarized trafficking of chemoattractant GPCRs during neutrophil chemotaxis. J Cell Sci. 2018;131: pubmed publisher
Chiasson MacKenzie C, Morris Z, Liu C, Bradford W, Koorman T, McClatchey A. Merlin/ERM proteins regulate growth factor-induced macropinocytosis and receptor recycling by organizing the plasma membrane:cytoskeleton interface. Genes Dev. 2018;32:1201-1214 pubmed publisher
Kim S, Lee Y, Tasaki T, Mun S, Hwang J, Kang M, et al. The N-recognin UBR4 of the N-end rule pathway is targeted to and required for the biogenesis of the early endosome. J Cell Sci. 2018;131: pubmed publisher
Colin A, Singaravelu P, Thery M, Blanchoin L, Gueroui Z. Actin-Network Architecture Regulates Microtubule Dynamics. Curr Biol. 2018;: pubmed publisher
Vasilev F, Limatola N, Park D, Kim U, Santella L, Chun J. Disassembly of Subplasmalemmal Actin Filaments Induces Cytosolic Ca2+ Increases in Astropecten aranciacus Eggs. Cell Physiol Biochem. 2018;48:2011-2034 pubmed publisher
Pécot T, Zengzhen L, Boulanger J, Salamero J, Kervrann C. A quantitative approach for analyzing the spatio-temporal distribution of 3D intracellular events in fluorescence microscopy. elife. 2018;7: pubmed publisher
Gut G, Herrmann M, Pelkmans L. Multiplexed protein maps link subcellular organization to cellular states. Science. 2018;361: pubmed publisher
Aihara E, Medina Candelaria N, Hanyu H, Matthis A, Engevik K, Gurniak C, et al. Cell injury triggers actin polymerization to initiate epithelial restitution. J Cell Sci. 2018;131: pubmed publisher
Mund M, van der Beek J, Deschamps J, Dmitrieff S, Hoess P, Monster J, et al. Systematic Nanoscale Analysis of Endocytosis Links Efficient Vesicle Formation to Patterned Actin Nucleation. Cell. 2018;174:884-896.e17 pubmed publisher
Singh V, Erady C, Balasubramanian N. Cell-matrix adhesion controls Golgi organization and function through Arf1 activation in anchorage-dependent cells. J Cell Sci. 2018;131: pubmed publisher
Mutalik S, Joseph J, Pullarkat P, Ghose A. Cytoskeletal Mechanisms of Axonal Contractility. Biophys J. 2018;115:713-724 pubmed publisher
Markwardt M, Snell N, Guo M, Wu Y, Christensen R, Liu H, et al. A Genetically Encoded Biosensor Strategy for Quantifying Non-muscle Myosin II Phosphorylation Dynamics in Living Cells and Organisms. Cell Rep. 2018;24:1060-1070.e4 pubmed publisher
Er E, Valiente M, Ganesh K, Zou Y, Agrawal S, Hu J, et al. Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization. Nat Cell Biol. 2018;20:966-978 pubmed publisher
Davies T, Kim H, Romano Spica N, Lesea Pringle B, Dumont J, Shirasu Hiza M, et al. Cell-intrinsic and -extrinsic mechanisms promote cell-type-specific cytokinetic diversity. elife. 2018;7: pubmed publisher
Schiavon C, Griffin M, Pirozzi M, Parashuraman R, Zhou W, Jinnah H, et al. Compositional complexity of rods and rings. Mol Biol Cell. 2018;29:2303-2316 pubmed publisher
Bai Y, Guo D, Sun X, Tang G, Liao T, Peng Y, et al. Balanced Rac1 activity controls formation and maintenance of neuromuscular acetylcholine receptor clusters. J Cell Sci. 2018;131: pubmed publisher
Ilacqua A, Price J, Graham B, Buccilli M, McKellar D, Damer C. Cyclic AMP signaling in Dictyostelium promotes the translocation of the copine family of calcium-binding proteins to the plasma membrane. BMC Cell Biol. 2018;19:13 pubmed publisher
Ohkawa T, Welch M. Baculovirus Actin-Based Motility Drives Nuclear Envelope Disruption and Nuclear Egress. Curr Biol. 2018;28:2153-2159.e4 pubmed publisher
Bakalar M, Joffe A, Schmid E, Son S, Podolski M, Fletcher D. Size-Dependent Segregation Controls Macrophage Phagocytosis of Antibody-Opsonized Targets. Cell. 2018;174:131-142.e13 pubmed publisher
Rieg A, Suleiman S, Anker C, Verjans E, Rossaint R, Uhlig S, et al. PDGF-BB regulates the pulmonary vascular tone: impact of prostaglandins, calcium, MAPK- and PI3K/AKT/mTOR signalling and actin polymerisation in pulmonary veins of guinea pigs. Respir Res. 2018;19:120 pubmed publisher
Trogdon M, Drawert B, Gomez C, Banavar S, Yi T, Campàs O, et al. The effect of cell geometry on polarization in budding yeast. PLoS Comput Biol. 2018;14:e1006241 pubmed publisher
Qin Z, Fisher G, Voorhees J, Quan T. Actin cytoskeleton assembly regulates collagen production via TGF-β type II receptor in human skin fibroblasts. J Cell Mol Med. 2018;22:4085-4096 pubmed publisher
Yamada M, Goshima G. The KCH Kinesin Drives Nuclear Transport and Cytoskeletal Coalescence to Promote Tip Cell Growth in Physcomitrella patens. Plant Cell. 2018;30:1496-1510 pubmed publisher
Habiba U, Kuroshima T, Yanagawa Matsuda A, Kitamura T, Chowdhury A, Jehung J, et al. HuR translocation to the cytoplasm of cancer cells in actin-independent manner. Exp Cell Res. 2018;369:218-225 pubmed publisher
Rodriguez Escudero I, Fernández Acero T, Cid V, Molina M. Heterologous mammalian Akt disrupts plasma membrane homeostasis by taking over TORC2 signaling in Saccharomyces cerevisiae. Sci Rep. 2018;8:7732 pubmed publisher
Mohagheghian E, Luo J, Chen J, Chaudhary G, Chen J, Sun J, et al. Quantifying compressive forces between living cell layers and within tissues using elastic round microgels. Nat Commun. 2018;9:1878 pubmed publisher
McKenzie A, Hicks S, Svec K, Naughton H, Edmunds Z, Howe A. The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation. Sci Rep. 2018;8:7228 pubmed publisher
Scholze M, Barbieux K, De Simone A, Boumasmoud M, Süess C, Wang R, et al. PI(4,5)P2 forms dynamic cortical structures and directs actin distribution as well as polarity in Caenorhabditis elegans embryos. Development. 2018;145: pubmed publisher
Artelt N, Ludwig T, Rogge H, Kavvadas P, Siegerist F, Blumenthal A, et al. The Role of Palladin in Podocytes. J Am Soc Nephrol. 2018;29:1662-1678 pubmed publisher
Tariqul Islam A, Yue H, Scavello M, Haldeman P, Rappel W, Charest P. The cAMP-induced G protein subunits dissociation monitored in live Dictyostelium cells by BRET reveals two activation rates, a positive effect of caffeine and potential role of microtubules. Cell Signal. 2018;48:25-37 pubmed publisher
Zheng W, Lin Y, Fang W, Zhao X, Lou Y, Wang G, et al. The endosomal recycling of FgSnc1 by FgSnx41-FgSnx4 heterodimer is essential for polarized growth and pathogenicity in Fusarium graminearum. New Phytol. 2018;219:654-671 pubmed publisher
Bielska E, Sisquella M, Aldeieg M, Birch C, O Donoghue E, May R. Pathogen-derived extracellular vesicles mediate virulence in the fatal human pathogen Cryptococcus gattii. Nat Commun. 2018;9:1556 pubmed publisher
Miller H, Larson C, Heinzen R. Actin polymerization in the endosomal pathway, but not on the Coxiella-containing vacuole, is essential for pathogen growth. PLoS Pathog. 2018;14:e1007005 pubmed publisher
Santinon G, Brian I, Pocaterra A, Romani P, Franzolin E, Rampazzo C, et al. dNTP metabolism links mechanical cues and YAP/TAZ to cell growth and oncogene-induced senescence. EMBO J. 2018;37: pubmed publisher
Rothenberg K, Scott D, Christoforou N, Hoffman B. Vinculin Force-Sensitive Dynamics at Focal Adhesions Enable Effective Directed Cell Migration. Biophys J. 2018;114:1680-1694 pubmed publisher
Shin W, Ge L, Arpino G, Villarreal S, HAMID E, Liu H, et al. Visualization of Membrane Pore in Live Cells Reveals a Dynamic-Pore Theory Governing Fusion and Endocytosis. Cell. 2018;173:934-945.e12 pubmed publisher
Lin W, Lin X, Fu S, Yang L, Tang C, Gao Y, et al. Pseudopod-associated protein KIF20B promotes Gli1-induced epithelial-mesenchymal transition modulated by pseudopodial actin dynamic in human colorectal cancer. Mol Carcinog. 2018;57:911-925 pubmed publisher
Maxson M, Naj X, O Meara T, Plumb J, Cowen L, Grinstein S. Integrin-based diffusion barrier separates membrane domains enabling the formation of microbiostatic frustrated phagosomes. elife. 2018;7: pubmed publisher
Nakayama H, Sakaue T, Maekawa M, Fujisaki A, Higashiyama S. Cullin 3 regulates ADAMs-mediated ectodomain shedding of amphiregulin. Biochem Biophys Res Commun. 2018;499:17-23 pubmed publisher
Sedgwick A, Olivia Balmert M, D SOUZA SCHOREY C. The formation of giant plasma membrane vesicles enable new insights into the regulation of cholesterol efflux. Exp Cell Res. 2018;365:194-207 pubmed publisher
Hovsepian J, Albanèse V, Becuwe M, Ivashov V, Teis D, Léon S. The yeast arrestin-related protein Bul1 is a novel actor of glucose-induced endocytosis. Mol Biol Cell. 2018;: pubmed publisher
Charles R, Bourmoum M, Claing A. ARF GTPases control phenotypic switching of vascular smooth muscle cells through the regulation of actin function and actin dependent gene expression. Cell Signal. 2018;46:64-75 pubmed publisher
Ayee M, LeMaster E, Teng T, Lee J, Levitan I. Hypotonic Challenge of Endothelial Cells Increases Membrane Stiffness with No Effect on Tether Force. Biophys J. 2018;114:929-938 pubmed publisher
Sundqvist M, Christenson K, Holdfeldt A, Gabl M, Mårtensson J, Björkman L, et al. Similarities and differences between the responses induced in human phagocytes through activation of the medium chain fatty acid receptor GPR84 and the short chain fatty acid receptor FFA2R. Biochim Biophys Acta Mol Cell Res. 2018;1865:695-708 pubmed publisher
Nakashima M, Watanabe M, Uchimaru K, Horie R. Trogocytosis of ligand-receptor complex and its intracellular transport in CD30 signalling. Biol Cell. 2018;110:109-124 pubmed publisher
Morita T, Hayashi K. Tumor Progression Is Mediated by Thymosin-β4 through a TGFβ/MRTF Signaling Axis. Mol Cancer Res. 2018;16:880-893 pubmed publisher
Freeman S, Vega A, Riedl M, Collins R, Ostrowski P, Woods E, et al. Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement. Cell. 2018;172:305-317.e10 pubmed publisher
Wu Z, Su M, Tong C, Wu M, Liu J. Membrane shape-mediated wave propagation of cortical protein dynamics. Nat Commun. 2018;9:136 pubmed publisher
Day K, Casler J, Glick B. Budding Yeast Has a Minimal Endomembrane System. Dev Cell. 2018;44:56-72.e4 pubmed publisher
Tu Y, Zhang L, Tong L, Wang Y, Zhang S, Wang R, et al. EFhd2/swiprosin-1 regulates LPS-induced macrophage recruitment via enhancing actin polymerization and cell migration. Int Immunopharmacol. 2018;55:263-271 pubmed publisher
Veerapathiran S, Wohland T. The imaging FCS diffusion law in the presence of multiple diffusive modes. Methods. 2018;140-141:140-150 pubmed publisher
Gagliardi P, Somale D, Puliafito A, Chiaverina G, di Blasio L, Oneto M, et al. MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion. J Cell Biol. 2018;217:231-249 pubmed publisher
Le V, Lee J, Chaterji S, Spencer A, Liu Y, Kim P, et al. Syndecan-1 in mechanosensing of nanotopological cues in engineered materials. Biomaterials. 2018;155:13-24 pubmed publisher
Curto M, Moro S, Yanguas F, Gutiérrez González C, Valdivieso M. The ancient claudin Dni2 facilitates yeast cell fusion by compartmentalizing Dni1 into a membrane subdomain. Cell Mol Life Sci. 2018;75:1687-1706 pubmed publisher
Deftu A, Filippi A, Gheorghe R, Ristoiu V. CXCL1 activates TRPV1 via Gi/o protein and actin filaments. Life Sci. 2018;193:282-291 pubmed publisher
Sugimoto W, Itoh K, Mitsui Y, Ebata T, Fujita H, Hirata H, et al. Substrate rigidity-dependent positive feedback regulation between YAP and ROCK2. Cell Adh Migr. 2018;12:101-108 pubmed publisher
Ly N, Tesch G, Nikolic Paterson D, Poronnik P. Proximal tubular epithelial cells preferentially endocytose covalently-modified albumin compared to native albumin. Nephrology (Carlton). 2017;: pubmed publisher
Renner M, Wang L, Levi S, Hennekinne L, Triller A. A Simple and Powerful Analysis of Lateral Subdiffusion Using Single Particle Tracking. Biophys J. 2017;113:2452-2463 pubmed publisher
Shirai Y, Tsunoyama T, Hiramoto Yamaki N, Hirosawa K, Shibata A, Kondo K, et al. Cortical actin nodes: Their dynamics and recruitment of podosomal proteins as revealed by super-resolution and single-molecule microscopy. PLoS ONE. 2017;12:e0188778 pubmed publisher
Viktorinova I, Henry I, Tomancak P. Epithelial rotation is preceded by planar symmetry breaking of actomyosin and protects epithelial tissue from cell deformations. PLoS Genet. 2017;13:e1007107 pubmed publisher
Strohmeyer N, Bharadwaj M, Costell M, Fassler R, Muller D. Fibronectin-bound ?5?1 integrins sense load and signal to reinforce adhesion in less than a second. Nat Mater. 2017;16:1262-1270 pubmed publisher
van der Kammen R, Song J, de Rink I, Janssen H, Madonna S, Scarponi C, et al. Knockout of the Arp2/3 complex in epidermis causes a psoriasis-like disease hallmarked by hyperactivation of transcription factor Nrf2. Development. 2017;144:4588-4603 pubmed publisher
Pielak R, O Donoghue G, Lin J, Alfieri K, Fay N, Low Nam S, et al. Early T cell receptor signals globally modulate ligand:receptor affinities during antigen discrimination. Proc Natl Acad Sci U S A. 2017;114:12190-12195 pubmed publisher
Banigan E, Stephens A, Marko J. Mechanics and Buckling of Biopolymeric Shells and Cell Nuclei. Biophys J. 2017;113:1654-1663 pubmed publisher
Patel D, Rorbach J, Downes K, Szukszto M, Pekalski M, Minczuk M. Macropinocytic entry of isolated mitochondria in epidermal growth factor-activated human osteosarcoma cells. Sci Rep. 2017;7:12886 pubmed publisher
Zhu R, Antoku S, Gundersen G. Centrifugal Displacement of Nuclei Reveals Multiple LINC Complex Mechanisms for Homeostatic Nuclear Positioning. Curr Biol. 2017;27:3097-3110.e5 pubmed publisher
Parisis N, Krasinska L, Harker B, Urbach S, Rossignol M, Camasses A, et al. Initiation of DNA replication requires actin dynamics and formin activity. EMBO J. 2017;36:3212-3231 pubmed publisher
Di Maio N, Vicidomini R, Angrisani A, Belli V, Furia M, Turano M. A new role for human dyskerin in vesicular trafficking. FEBS Open Bio. 2017;7:1453-1468 pubmed publisher
Daste F, Walrant A, Holst M, Gadsby J, Mason J, Lee J, et al. Control of actin polymerization via the coincidence of phosphoinositides and high membrane curvature. J Cell Biol. 2017;216:3745-3765 pubmed publisher
Berglund L, Hao X, Liu B, Grantham J, Nystrom T. Differential effects of soluble and aggregating polyQ proteins on cytotoxicity and type-1 myosin-dependent endocytosis in yeast. Sci Rep. 2017;7:11328 pubmed publisher
Escobar Aguirre M, Zhang H, Jamieson Lucy A, Mullins M. Microtubule-actin crosslinking factor 1 (Macf1) domain function in Balbiani body dissociation and nuclear positioning. PLoS Genet. 2017;13:e1006983 pubmed publisher
Gabl M, Holdfeldt A, Sundqvist M, Lomei J, Dahlgren C, Forsman H. FPR2 signaling without ?-arrestin recruitment alters the functional repertoire of neutrophils. Biochem Pharmacol. 2017;145:114-122 pubmed publisher
Tomoshige S, Kobayashi Y, Hosoba K, Hamamoto A, Miyamoto T, Saito Y. Cytoskeleton-related regulation of primary cilia shortening mediated by melanin-concentrating hormone receptor 1. Gen Comp Endocrinol. 2017;253:44-52 pubmed publisher
Dayam R, Sun C, Choy C, Mancuso G, Glogauer M, Botelho R. The Lipid Kinase PIKfyve Coordinates the Neutrophil Immune Response through the Activation of the Rac GTPase. J Immunol. 2017;199:2096-2105 pubmed publisher
Kustermann J, Wu Y, Rieger L, Dedden D, Phan T, Walther P, et al. The cell polarity proteins Boi1p and Boi2p stimulate vesicle fusion at the plasma membrane of yeast cells. J Cell Sci. 2017;130:2996-3008 pubmed publisher
Burbage M, Keppler S, Montaner B, Mattila P, Batista F. The Small Rho GTPase TC10 Modulates B Cell Immune Responses. J Immunol. 2017;199:1682-1695 pubmed publisher
Leyton Puig D, Isogai T, Argenzio E, van den Broek B, Klarenbeek J, Janssen H, et al. Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors. Nat Commun. 2017;8:16068 pubmed publisher
Zheng C, Zhang F, Bao X, Wu S, Wang P, Zhou J, et al. Polarized Distribution of Active Myosin II Regulates Directional Migration of Cultured Olfactory Ensheathing Cells. Sci Rep. 2017;7:4701 pubmed publisher
Kushiro K, Yaginuma T, Ryo A, Takai M. Differences in Three-Dimensional Geometric Recognition by Non-Cancerous and Cancerous Epithelial Cells on Microgroove-Based Topography. Sci Rep. 2017;7:4244 pubmed publisher
Lim Y, Lo H, Ferguson C, Martel N, Giacomotto J, Gomez G, et al. Caveolae Protect Notochord Cells against Catastrophic Mechanical Failure during Development. Curr Biol. 2017;27:1968-1981.e7 pubmed publisher
Ren H, Dang X, Cai X, Yu P, Li Y, Zhang S, et al. Spatio-temporal orientation of microtubules controls conical cell shape in Arabidopsis thaliana petals. PLoS Genet. 2017;13:e1006851 pubmed publisher
Wang W, Ju Y, Zhou Q, Tang J, Li M, Zhang L, et al. The Small GTPase Rac1 Contributes to Extinction of Aversive Memories of Drug Withdrawal by Facilitating GABAA Receptor Endocytosis in the vmPFC. J Neurosci. 2017;37:7096-7110 pubmed publisher
Goo M, Sancho L, Slepak N, Boassa D, Deerinck T, Ellisman M, et al. Activity-dependent trafficking of lysosomes in dendrites and dendritic spines. J Cell Biol. 2017;216:2499-2513 pubmed publisher
Kilaru S, Schuster M, Ma W, Steinberg G. Fluorescent markers of various organelles in the wheat pathogen Zymoseptoria tritici. Fungal Genet Biol. 2017;105:16-27 pubmed publisher
Kristó I, Bajusz C, Borsos B, Pankotai T, Dopie J, Jankovics F, et al. The actin binding cytoskeletal protein Moesin is involved in nuclear mRNA export. Biochim Biophys Acta Mol Cell Res. 2017;1864:1589-1604 pubmed publisher
Killilea A, Csencsits R, Le E, Patel A, Kenny S, Xu K, et al. Cytoskeletal organization in microtentacles. Exp Cell Res. 2017;357:291-298 pubmed publisher
González Jamett A, Guerra M, Olivares M, Haro Acuña V, Báez Matus X, Vasquez Navarrete J, et al. The F-Actin Binding Protein Cortactin Regulates the Dynamics of the Exocytotic Fusion Pore through its SH3 Domain. Front Cell Neurosci. 2017;11:130 pubmed publisher
Totaro A, Castellan M, Battilana G, Zanconato F, Azzolin L, Giulitti S, et al. YAP/TAZ link cell mechanics to Notch signalling to control epidermal stem cell fate. Nat Commun. 2017;8:15206 pubmed publisher
Kaminuma O, Katayama K, Inoue K, Saeki M, Nishimura T, Kitamura N, et al. Hyper-reactive cloned mice generated by direct nuclear transfer of antigen-specific CD4+ T cells. EMBO Rep. 2017;18:885-893 pubmed publisher
Roux A, Loranger A, Lavoie J, Marceau N. Keratin 8/18 regulation of insulin receptor signaling and trafficking in hepatocytes through a concerted phosphoinositide-dependent Akt and Rab5 modulation. FASEB J. 2017;31:3555-3573 pubmed publisher
Yamada M, Tanaka Takiguchi Y, Hayashi M, Nishina M, Goshima G. Multiple kinesin-14 family members drive microtubule minus end-directed transport in plant cells. J Cell Biol. 2017;216:1705-1714 pubmed publisher
Leduc C, Etienne Manneville S. Regulation of microtubule-associated motors drives intermediate filament network polarization. J Cell Biol. 2017;216:1689-1703 pubmed publisher
Rai U, Najm F, Tartakoff A. Nucleolar asymmetry and the importance of septin integrity upon cell cycle arrest. PLoS ONE. 2017;12:e0174306 pubmed publisher
Herbomel G, Hatte G, Roul J, Padilla Parra S, Tassan J, Tramier M. Actomyosin-generated tension on cadherin is similar between dividing and non-dividing epithelial cells in early Xenopus laevis embryos. Sci Rep. 2017;7:45058 pubmed publisher
Wang J, Lee J, Christian S, Dang Lawson M, Pritchard C, Freeman S, et al. The Rap1-cofilin-1 pathway coordinates actin reorganization and MTOC polarization at the B cell immune synapse. J Cell Sci. 2017;130:1094-1109 pubmed publisher
Sorrentino G, Ruggeri N, Zannini A, Ingallina E, Bertolio R, Marotta C, et al. Glucocorticoid receptor signalling activates YAP in breast cancer. Nat Commun. 2017;8:14073 pubmed publisher
McLeish K, Merchant M, Creed T, Tandon S, Barati M, Uriarte S, et al. Frontline Science: Tumor necrosis factor-? stimulation and priming of human neutrophil granule exocytosis. J Leukoc Biol. 2017;102:19-29 pubmed publisher
Stephens A, Banigan E, Adam S, Goldman R, Marko J. Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus. Mol Biol Cell. 2017;28:1984-1996 pubmed publisher
Yang H, Osakada H, Kojidani T, Haraguchi T, Hiraoka Y. Lipid droplet dynamics during Schizosaccharomyces pombe sporulation and their role in spore survival. Biol Open. 2017;6:217-222 pubmed publisher
Kunschmann T, Puder S, Fischer T, Perez J, Wilharm N, Mierke C. Integrin-linked kinase regulates cellular mechanics facilitating the motility in 3D extracellular matrices. Biochim Biophys Acta Mol Cell Res. 2017;1864:580-593 pubmed publisher
Zhu H, Xue C, Xu X, Guo Y, Li X, Lu J, et al. Rab8a/Rab11a regulate intercellular communications between neural cells via tunneling nanotubes. Cell Death Dis. 2016;7:e2523 pubmed publisher
Huang S, Lim S, Gupta A, Bag N, Wohland T. Plasma membrane organization and dynamics is probe and cell line dependent. Biochim Biophys Acta Biomembr. 2017;1859:1483-1492 pubmed publisher
Jastrzębski K, Zdżalik Bielecka D, Mamińska A, Kalaidzidis Y, Hellberg C, Miaczynska M. Multiple routes of endocytic internalization of PDGFR? contribute to PDGF-induced STAT3 signaling. J Cell Sci. 2017;130:577-589 pubmed publisher
Lee J, Sengupta P, Brzostowski J, Lippincott Schwartz J, Pierce S. The nanoscale spatial organization of B-cell receptors on immunoglobulin M- and G-expressing human B-cells. Mol Biol Cell. 2017;28:511-523 pubmed publisher
Hoya M, Yanguas F, Moro S, Prescianotto Baschong C, Doncel C, de Leon N, et al. Traffic Through the Trans-Golgi Network and the Endosomal System Requires Collaboration Between Exomer and Clathrin Adaptors in Fission Yeast. Genetics. 2017;205:673-690 pubmed publisher
Silva A, Osorio D, Pereira A, Maiato H, Pinto I, Rubinstein B, et al. Robust gap repair in the contractile ring ensures timely completion of cytokinesis. J Cell Biol. 2016;215:789-799 pubmed
Csanyi G, Feck D, Ghoshal P, Singla B, Lin H, Nagarajan S, et al. CD47 and Nox1 Mediate Dynamic Fluid-Phase Macropinocytosis of Native LDL. Antioxid Redox Signal. 2017;26:886-901 pubmed publisher
Hamm M, Kirchmaier B, Herzog W. Sema3d controls collective endothelial cell migration by distinct mechanisms via Nrp1 and PlxnD1. J Cell Biol. 2016;215:415-430 pubmed
Irianto J, Pfeifer C, Bennett R, Xia Y, Ivanovska I, Liu A, et al. Nuclear constriction segregates mobile nuclear proteins away from chromatin. Mol Biol Cell. 2016;27:4011-4020 pubmed
Tanaka K, Osada H, Murakami Tonami Y, Horio Y, Hida T, Sekido Y. Statin suppresses Hippo pathway-inactivated malignant mesothelioma cells and blocks the YAP/CD44 growth stimulatory axis. Cancer Lett. 2017;385:215-224 pubmed publisher
Luo W, Lieu Z, Manser E, Bershadsky A, Sheetz M. Formin DAAM1 Organizes Actin Filaments in the Cytoplasmic Nodal Actin Network. PLoS ONE. 2016;11:e0163915 pubmed publisher
Lee C, Lou J, Wen K, McKane M, Eskin S, Rubenstein P, et al. Regulation of actin catch-slip bonds with a RhoA-formin module. Sci Rep. 2016;6:35058 pubmed publisher
XU C, Fu X, Zhu S, Liu J. Retrolinkin recruits the WAVE1 protein complex to facilitate BDNF-induced TrkB endocytosis and dendrite outgrowth. Mol Biol Cell. 2016;27:3342-3356 pubmed
Wen P, Grenklo S, Arpino G, Tan X, Liao H, Heureaux J, et al. Actin dynamics provides membrane tension to merge fusing vesicles into the plasma membrane. Nat Commun. 2016;7:12604 pubmed publisher
Maninová M, Vomastek T. Dorsal stress fibers, transverse actin arcs, and perinuclear actin fibers form an interconnected network that induces nuclear movement in polarizing fibroblasts. FEBS J. 2016;283:3676-3693 pubmed publisher
Seno T, Ikeno T, Mennya K, Kurishita M, Sakae N, Sato M, et al. Kinesin-1 sorting in axons controls the differential retraction of arbor terminals. J Cell Sci. 2016;129:3499-510 pubmed publisher
Kumawat K, Koopmans T, Menzen M, Prins A, Smit M, Halayko A, et al. Cooperative signaling by TGF-β1 and WNT-11 drives sm-α-actin expression in smooth muscle via Rho kinase-actin-MRTF-A signaling. Am J Physiol Lung Cell Mol Physiol. 2016;311:L529-37 pubmed publisher
Sinha S, Hoshino D, Hong N, Kirkbride K, Grega Larson N, Seiki M, et al. Cortactin promotes exosome secretion by controlling branched actin dynamics. J Cell Biol. 2016;214:197-213 pubmed publisher
Małota K, Swiatek P. Analysis of the cytoskeleton organization and its possible functions in male earthworm germ-line cysts equipped with a cytophore. Cell Tissue Res. 2016;366:175-89 pubmed publisher
Elbediwy A, Vincent Mistiaen Z, Spencer Dene B, Stone R, Boeing S, Wculek S, et al. Integrin signalling regulates YAP and TAZ to control skin homeostasis. Development. 2016;143:1674-87 pubmed publisher
Liao X, Meena N, Southall N, Liu L, Swaroop M, Zhang A, et al. A High-Throughput, Multi-Cell Phenotype Assay for the Identification of Novel Inhibitors of Chemotaxis/Migration. Sci Rep. 2016;6:22273 pubmed publisher
Huang Y, Hoffmann G, Wheeler B, Schiapparelli P, Quinones Hinojosa A, Searson P. Cellular microenvironment modulates the galvanotaxis of brain tumor initiating cells. Sci Rep. 2016;6:21583 pubmed publisher
Vituret C, Gallay K, Confort M, Ftaich N, Matei C, Archer F, et al. Transfer of the Cystic Fibrosis Transmembrane Conductance Regulator to Human Cystic Fibrosis Cells Mediated by Extracellular Vesicles. Hum Gene Ther. 2016;27:166-83 pubmed publisher
Hermann M, Jakobson M, Colo G, Rognoni E, Jakobson M, Kupatt C, et al. Integrins synergise to induce expression of the MRTF-A-SRF target gene ISG15 for promoting cancer cell invasion. J Cell Sci. 2016;129:1391-403 pubmed publisher
Stewart K, Gaitan Y, Shafer M, Aoudjit L, Hu D, Sharma R, et al. A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects. PLoS Genet. 2016;12:e1005785 pubmed publisher
Brzeska H, Koech H, Pridham K, Korn E, Titus M. Selective localization of myosin-I proteins in macropinosomes and actin waves. Cytoskeleton (Hoboken). 2016;73:68-82 pubmed publisher
Cheney K, White A, Mudianta I, Winters A, Quezada M, Capon R, et al. Choose Your Weaponry: Selective Storage of a Single Toxic Compound, Latrunculin A, by Closely Related Nudibranch Molluscs. PLoS ONE. 2016;11:e0145134 pubmed publisher
Chen J, Zhou W, Jia Q, Chen J, Zhang S, Yao W, et al. Efficient extravasation of tumor-repopulating cells depends on cell deformability. Sci Rep. 2016;6:19304 pubmed publisher
Zhang S, Duan L, Qian H, Yu X. Actin Aggregations Mark the Sites of Neurite Initiation. Neurosci Bull. 2016;32:1-15 pubmed publisher
Gasparrini F, Feest C, Bruckbauer A, Mattila P, Muller J, Nitschke L, et al. Nanoscale organization and dynamics of the siglec CD22 cooperate with the cytoskeleton in restraining BCR signalling. EMBO J. 2016;35:258-80 pubmed publisher
Connor Y, Tekleab S, Nandakumar S, Walls C, Tekleab Y, Husain A, et al. Physical nanoscale conduit-mediated communication between tumour cells and the endothelium modulates endothelial phenotype. Nat Commun. 2015;6:8671 pubmed publisher
Yao P, Petralia R, Ott C, Wang Y, Lippincott Schwartz J, Mattson M. Dendrosomatic Sonic Hedgehog Signaling in Hippocampal Neurons Regulates Axon Elongation. J Neurosci. 2015;35:16126-41 pubmed publisher
Guimaraes S, Schuster M, Bielska E, Dagdas G, Kilaru S, Meadows B, et al. Peroxisomes, lipid droplets, and endoplasmic reticulum "hitchhike" on motile early endosomes. J Cell Biol. 2015;211:945-54 pubmed publisher
Zlotek Zlotkiewicz E, Monnier S, Cappello G, Le Berre M, Piel M. Optical volume and mass measurements show that mammalian cells swell during mitosis. J Cell Biol. 2015;211:765-74 pubmed publisher
Suzuki R, Hotta K, Oka K. Spatiotemporal quantification of subcellular ATP levels in a single HeLa cell during changes in morphology. Sci Rep. 2015;5:16874 pubmed publisher
Guetta Terrier C, Monzo P, Zhu J, Long H, Venkatraman L, Zhou Y, et al. Protrusive waves guide 3D cell migration along nanofibers. J Cell Biol. 2015;211:683-701 pubmed publisher
Martínez Núñez L, Riquelme M. Role of BGT-1 and BGT-2, two predicted GPI-anchored glycoside hydrolases/glycosyltransferases, in cell wall remodeling in Neurospora crassa. Fungal Genet Biol. 2015;85:58-70 pubmed publisher
Li G, Wang Y, Yan M, Xu Y, Song X, Li Q, et al. Inhibition of actin polymerization in the NAc shell inhibits morphine-induced CPP by disrupting its reconsolidation. Sci Rep. 2015;5:16283 pubmed publisher
Liu L, Li J, Zhang L, Zhang F, Zhang R, Chen X, et al. Cofilin phosphorylation is elevated after F-actin disassembly induced by Rac1 depletion. Biofactors. 2015;41:352-9 pubmed publisher
Zhang Q, Kota K, Alam S, Nickerson J, Dickinson R, Lele T. Coordinated Dynamics of RNA Splicing Speckles in the Nucleus. J Cell Physiol. 2016;231:1269-75 pubmed publisher
Chiasson MacKenzie C, Morris Z, BACA Q, Morris B, Coker J, Mirchev R, et al. NF2/Merlin mediates contact-dependent inhibition of EGFR mobility and internalization via cortical actomyosin. J Cell Biol. 2015;211:391-405 pubmed publisher
Hicks L, Liu G, Ukken F, Lu S, Bollinger K, O Connor Giles K, et al. Depletion or over-expression of Sh3px1 results in dramatic changes in cell morphology. Biol Open. 2015;4:1448-61 pubmed publisher
Ongherth A, Pasch S, Wuertz C, Nowak K, Kittana N, Weis C, et al. p63RhoGEF regulates auto- and paracrine signaling in cardiac fibroblasts. J Mol Cell Cardiol. 2015;88:39-54 pubmed publisher
Winkler F, Gummalla M, Künneke L, Lv Z, Zippelius A, Aspelmeier T, et al. Fluctuation Analysis of Centrosomes Reveals a Cortical Function of Kinesin-1. Biophys J. 2015;109:856-68 pubmed publisher
Hong N, Qi A, Weaver A. PI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin-actin interactions. J Cell Biol. 2015;210:753-69 pubmed publisher
Limatola N, Chun J, Kyozuka K, Santella L. Novel Ca2+ increases in the maturing oocytes of starfish during the germinal vesicle breakdown. Cell Calcium. 2015;58:500-10 pubmed publisher
Moreau K, Ghislat G, Hochfeld W, Renna M, Zavodszky E, Runwal G, et al. Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy. Nat Commun. 2015;6:8045 pubmed publisher
Li Y, Lovett D, Zhang Q, Neelam S, Kuchibhotla R, Zhu R, et al. Moving Cell Boundaries Drive Nuclear Shaping during Cell Spreading. Biophys J. 2015;109:670-86 pubmed publisher
Sato M, Koriyama M, Watanabe S, Ohtsuka M, Sakurai T, Inada E, et al. Direct Injection of CRISPR/Cas9-Related mRNA into Cytoplasm of Parthenogenetically Activated Porcine Oocytes Causes Frequent Mosaicism for Indel Mutations. Int J Mol Sci. 2015;16:17838-56 pubmed publisher
Roybal K, Mace E, Clark D, Leard A, Herman A, Verkade P, et al. Modest Interference with Actin Dynamics in Primary T Cell Activation by Antigen Presenting Cells Preferentially Affects Lamellal Signaling. PLoS ONE. 2015;10:e0133231 pubmed publisher
Ganguly A, Tang Y, Wang L, Ladt K, Loi J, Dargent B, et al. A dynamic formin-dependent deep F-actin network in axons. J Cell Biol. 2015;210:401-17 pubmed publisher
Idevall Hagren O, Lü A, Xie B, De Camilli P. Triggered Ca2+ influx is required for extended synaptotagmin 1-induced ER-plasma membrane tethering. EMBO J. 2015;34:2291-305 pubmed publisher
Gabl M, Winther M, Welin A, Karlsson A, Oprea T, Bylund J, et al. P2Y2 receptor signaling in neutrophils is regulated from inside by a novel cytoskeleton-dependent mechanism. Exp Cell Res. 2015;336:242-52 pubmed publisher
Fuhrmann A, Engler A. The cytoskeleton regulates cell attachment strength. Biophys J. 2015;109:57-65 pubmed publisher
Reverey J, Jeon J, Bao H, Leippe M, Metzler R, Selhuber Unkel C. Superdiffusion dominates intracellular particle motion in the supercrowded cytoplasm of pathogenic Acanthamoeba castellanii. Sci Rep. 2015;5:11690 pubmed publisher
Chabaud M, Heuzé M, Bretou M, Vargas P, Maiuri P, Solanes P, et al. Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells. Nat Commun. 2015;6:7526 pubmed publisher
Kilaru S, Schuster M, Latz M, Guo M, Steinberg G. Fluorescent markers of the endocytic pathway in Zymoseptoria tritici. Fungal Genet Biol. 2015;79:150-7 pubmed publisher
Mooren O, Kim J, Li J, Cooper J. Role of N-WASP in Endothelial Monolayer Formation and Integrity. J Biol Chem. 2015;290:18796-805 pubmed publisher
Serbo J, KUO S, LEWIS S, Lehmann M, Li J, Gracias D, et al. Patterning of Fibroblast and Matrix Anisotropy within 3D Confinement is Driven by the Cytoskeleton. Adv Healthc Mater. 2016;5:146-58 pubmed publisher
Cavolo S, Zhou C, Ketcham S, Suzuki M, Ukalovic K, Silverman M, et al. Mycalolide B dissociates dynactin and abolishes retrograde axonal transport of dense-core vesicles. Mol Biol Cell. 2015;26:2664-72 pubmed publisher
Gagliardi P, Puliafito A, di Blasio L, Chianale F, Somale D, Seano G, et al. Real-time monitoring of cell protrusion dynamics by impedance responses. Sci Rep. 2015;5:10206 pubmed publisher
Shao X, Li Q, Mogilner A, Bershadsky A, Shivashankar G. Mechanical stimulation induces formin-dependent assembly of a perinuclear actin rim. Proc Natl Acad Sci U S A. 2015;112:E2595-601 pubmed publisher
Chimura T, Launey T, Yoshida N. Calpain-Mediated Degradation of Drebrin by Excitotoxicity In vitro and In vivo. PLoS ONE. 2015;10:e0125119 pubmed publisher
Padmanabhan R, Taneyhill L. Cadherin-6B undergoes macropinocytosis and clathrin-mediated endocytosis during cranial neural crest cell EMT. J Cell Sci. 2015;128:1773-86 pubmed publisher
Stratigi K, Kapsetaki M, Aivaliotis M, Town T, Flavell R, Spilianakis C. Spatial proximity of homologous alleles and long noncoding RNAs regulate a switch in allelic gene expression. Proc Natl Acad Sci U S A. 2015;112:E1577-86 pubmed publisher
Bastian A, Thorpe J, Disch B, Bailey Downs L, Gangjee A, Devambatla R, et al. A small molecule with anticancer and antimetastatic activities induces rapid mitochondrial-associated necrosis in breast cancer. J Pharmacol Exp Ther. 2015;353:392-404 pubmed publisher
Lee C, Dagnino Acosta A, Yarotskyy V, Hanna A, Lyfenko A, Knoblauch M, et al. Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function. Skelet Muscle. 2015;5:4 pubmed publisher
Jolly A, Takawira D, Oke O, Whiteside S, Chang S, Wen E, et al. Pseudomonas aeruginosa-induced bleb-niche formation in epithelial cells is independent of actinomyosin contraction and enhanced by loss of cystic fibrosis transmembrane-conductance regulator osmoregulatory function. MBio. 2015;6:e02533 pubmed publisher
Ito T, Taniguchi H, Fukagai K, Okamuro S, Kobayashi A. Inhibitory mechanism of FAT4 gene expression in response to actin dynamics during Src-induced carcinogenesis. PLoS ONE. 2015;10:e0118336 pubmed publisher
Hobeika E, Levit Zerdoun E, Anastasopoulou V, Pohlmeyer R, Altmeier S, Alsadeq A, et al. CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk. EMBO J. 2015;34:925-39 pubmed publisher
Stankova V, Tsikolia N, Viebahn C. Rho kinase activity controls directional cell movements during primitive streak formation in the rabbit embryo. Development. 2015;142:92-8 pubmed publisher
Carey S, Rahman A, Kraning Rush C, Romero B, Somasegar S, Torre O, et al. Comparative mechanisms of cancer cell migration through 3D matrix and physiological microtracks. Am J Physiol Cell Physiol. 2015;308:C436-47 pubmed publisher
Lee H, Huh S, Hur D, Jeong H, Kim T, Kim S, et al. ERDR1 enhances human NK cell cytotoxicity through an actin-regulated degranulation-dependent pathway. Cell Immunol. 2014;292:78-84 pubmed
Heidary Arash E, Song K, Song S, Shiban A, Attisano L. Arhgef7 promotes activation of the Hippo pathway core kinase Lats. EMBO J. 2014;33:2997-3011 pubmed publisher
Sainath R, Gallo G. The dynein inhibitor Ciliobrevin D inhibits the bidirectional transport of organelles along sensory axons and impairs NGF-mediated regulation of growth cones and axon branches. Dev Neurobiol. 2015;75:757-77 pubmed publisher
Becuwe M, Léon S. Integrated control of transporter endocytosis and recycling by the arrestin-related protein Rod1 and the ubiquitin ligase Rsp5. elife. 2014;3: pubmed publisher
Burkard C, Verheije M, Wicht O, van Kasteren S, van Kuppeveld F, Haagmans B, et al. Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner. PLoS Pathog. 2014;10:e1004502 pubmed publisher
Ma L, Li Y, Peng J, Wu D, Zhao X, Cui Y, et al. Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration. Cell Res. 2015;25:24-38 pubmed publisher
Welin A, Björnsdottir H, Winther M, Christenson K, Oprea T, Karlsson A, et al. CFP-10 from Mycobacterium tuberculosis selectively activates human neutrophils through a pertussis toxin-sensitive chemotactic receptor. Infect Immun. 2015;83:205-13 pubmed publisher
Gabl M, Winther M, Skovbakke S, Bylund J, Dahlgren C, Forsman H. A pepducin derived from the third intracellular loop of FPR2 is a partial agonist for direct activation of this receptor in neutrophils but a full agonist for cross-talk triggered reactivation of FPR2. PLoS ONE. 2014;9:e109516 pubmed publisher
Fiorentino I, Gualtieri R, Barbato V, Mollo V, Braun S, Angrisani A, et al. Energy independent uptake and release of polystyrene nanoparticles in primary mammalian cell cultures. Exp Cell Res. 2015;330:240-7 pubmed publisher
Doller A, Badawi A, Schmid T, Brauss T, Pleli T, zu Heringdorf D, et al. The cytoskeletal inhibitors latrunculin A and blebbistatin exert antitumorigenic properties in human hepatocellular carcinoma cells by interfering with intracellular HuR trafficking. Exp Cell Res. 2015;330:66-80 pubmed publisher
Nath S, Munsie L, Truant R. A huntingtin-mediated fast stress response halting endosomal trafficking is defective in Huntington's disease. Hum Mol Genet. 2015;24:450-62 pubmed publisher
Han S, Melichar H, Coombes J, Chan S, Koshy A, Boothroyd J, et al. Internalization and TLR-dependent type I interferon production by monocytes in response to Toxoplasma gondii. Immunol Cell Biol. 2014;92:872-81 pubmed publisher
Jullié D, Choquet D, Perrais D. Recycling endosomes undergo rapid closure of a fusion pore on exocytosis in neuronal dendrites. J Neurosci. 2014;34:11106-18 pubmed publisher
Boudreau L, Duchez A, Cloutier N, Soulet D, Martin N, Bollinger J, et al. Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation. Blood. 2014;124:2173-83 pubmed publisher
Kläsener K, Maity P, Hobeika E, Yang J, Reth M. B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk. elife. 2014;3:e02069 pubmed publisher
Zila V, Difato F, Klimova L, Huerfano S, Forstova J. Involvement of microtubular network and its motors in productive endocytic trafficking of mouse polyomavirus. PLoS ONE. 2014;9:e96922 pubmed publisher
Mutlu N, Garipler G, Akdoğan E, Dunn C. Activation of the pleiotropic drug resistance pathway can promote mitochondrial DNA retention by fusion-defective mitochondria in Saccharomyces cerevisiae. G3 (Bethesda). 2014;4:1247-58 pubmed publisher
Lei Q, Pan X, Chang S, Malkowicz S, Guzzo T, Malykhina A. Response of the human detrusor to stretch is regulated by TREK-1, a two-pore-domain (K2P) mechano-gated potassium channel. J Physiol. 2014;592:3013-30 pubmed publisher
Wang T, Yanger K, Stanger B, Cassio D, Bi E. Cytokinesis defines a spatial landmark for hepatocyte polarization and apical lumen formation. J Cell Sci. 2014;127:2483-92 pubmed publisher
Franco Villanueva A, Fernández López E, Gabandé Rodríguez E, Bañón Rodríguez I, Esteban J, Anton I, et al. WIP modulates dendritic spine actin cytoskeleton by transcriptional control of lipid metabolic enzymes. Hum Mol Genet. 2014;23:4383-95 pubmed publisher
Onnheim K, Christenson K, Gabl M, Burbiel J, Muller C, Oprea T, et al. A novel receptor cross-talk between the ATP receptor P2Y2 and formyl peptide receptors reactivates desensitized neutrophils to produce superoxide. Exp Cell Res. 2014;323:209-17 pubmed publisher
Shimizu Y, Kushida Y, Kiriyama S, Nakano K, Numata O. Formation and ingression of division furrow can progress under the inhibitory condition of actin polymerization in ciliate Tetrahymena pyriformis. Zoolog Sci. 2013;30:1044-9 pubmed publisher
Wang B, Kuo J, Granick S. Bursts of active transport in living cells. Phys Rev Lett. 2013;111:208102 pubmed
Aucher A, Rudnicka D, Davis D. MicroRNAs transfer from human macrophages to hepato-carcinoma cells and inhibit proliferation. J Immunol. 2013;191:6250-60 pubmed publisher
Majoul I, Gao L, Betzig E, Onichtchouk D, Butkevich E, Kozlov Y, et al. Fast structural responses of gap junction membrane domains to AB5 toxins. Proc Natl Acad Sci U S A. 2013;110:E4125-33 pubmed publisher
Quinlan M. Direct interaction between two actin nucleators is required in Drosophila oogenesis. Development. 2013;140:4417-25 pubmed publisher
Shimada K, Filipuzzi I, Stahl M, Helliwell S, Studer C, Hoepfner D, et al. TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks. Mol Cell. 2013;51:829-39 pubmed publisher
Heikkilä O, Susi P, Tevaluoto T, Härmä H, Marjomaki V, Hyypia T, et al. Internalization of coxsackievirus A9 is mediated by {beta}2-microglobulin, dynamin, and Arf6 but not by caveolin-1 or clathrin. J Virol. 2010;84:3666-81 pubmed publisher
Lahaye X, Vidy A, Pomier C, Obiang L, Harper F, Gaudin Y, et al. Functional characterization of Negri bodies (NBs) in rabies virus-infected cells: Evidence that NBs are sites of viral transcription and replication. J Virol. 2009;83:7948-58 pubmed publisher
Young K, Thurston S, Copeland S, Smallwood C, Copeland J. INF1 is a novel microtubule-associated formin. Mol Biol Cell. 2008;19:5168-80 pubmed publisher
Yarmola E, Somasundaram T, Boring T, Spector I, Bubb M. Actin-latrunculin A structure and function. Differential modulation of actin-binding protein function by latrunculin A. J Biol Chem. 2000;275:28120-7 pubmed
Coue M, Brenner S, Spector I, Korn E. Inhibition of actin polymerization by latrunculin A. FEBS Lett. 1987;213:316-8 pubmed
de Oliveira C, Mantovani B. Latrunculin A is a potent inhibitor of phagocytosis by macrophages. Life Sci. 1988;43:1825-30 pubmed
product information
Catalog Number :
L5163
Product Name :
Latrunculin A
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
from sea sponge, ≥85% (HPLC), waxy solid
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA