product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-L1CAM antibody, Mouse monoclonal
catalog :
L4543
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
UJ127.11
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, blocking or activating experiments, western blot knockout validation
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; fig 10
Patzke C, Acuna C, Giam L, Wernig M, Südhof T. Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation. J Exp Med. 2016;213:499-515 pubmed publisher
  • western blot; human; loading ...; fig 5e
Patzke C, Brockmann M, Dai J, Gan K, Grauel M, Fenske P, et al. Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses. Cell. 2019;179:498-513.e22 pubmed publisher
  • blocking or activating experiments; human
  • western blot; human; 1:1000; fig 4a
Lund K, Dembinski J, Solberg N, Urbanucci A, Mills I, Krauss S. Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment. PLoS ONE. 2015;10:e0123684 pubmed publisher
Liu S, Magill S, Vasudevan H, Hilz S, Villanueva Meyer J, Lastella S, et al. Multiplatform Molecular Profiling Reveals Epigenomic Intratumor Heterogeneity in Ependymoma. Cell Rep. 2020;30:1300-1309.e5 pubmed publisher
Wang L, Liu L, Li H, Wang P, Hu Z, Wei Y, et al. RELA Fusion in Supratentorial Extraventricular Ependymomas: A Morphologic, Immunohistochemical, and Molecular Study of 43 Cases. Am J Surg Pathol. 2019;43:1674-1681 pubmed publisher
Stevers M, Rabban J, Garg K, Van Ziffle J, Onodera C, Grenert J, et al. Well-differentiated papillary mesothelioma of the peritoneum is genetically defined by mutually exclusive mutations in TRAF7 and CDC42. Mod Pathol. 2019;32:88-99 pubmed publisher
Hirose T, Nobusawa S, Sugiyama K, Amatya V, Fujimoto N, Sasaki A, et al. Astroblastoma: a distinct tumor entity characterized by alterations of the X chromosome and MN1 rearrangement. Brain Pathol. 2017;: pubmed publisher
Warren C, Griffin L, Little A, Huang I, Farzan M, Pyeon D. The antiviral restriction factors IFITM1, 2 and 3 do not inhibit infection of human papillomavirus, cytomegalovirus and adenovirus. PLoS ONE. 2014;9:e96579 pubmed publisher
Parker M, Mohankumar K, Punchihewa C, Weinlich R, Dalton J, Li Y, et al. C11orf95-RELA fusions drive oncogenic NF-?B signalling in ependymoma. Nature. 2014;506:451-5 pubmed publisher
product information
Product No. :
L4543
Product Name :
Anti-L1CAM antibody, Mouse monoclonal
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
UJ127.11
Applications/Description :
Suitable for flow cytometry; western blot: 0.25-0.5 μg/mL using cell extracts of G361 cells (human melanoma); microarray; immunoprecipitation (IP); immunohistochemistry; immunocytochemistry
Species Reactivity :
human
Isotype :
IgG1
Concentration :
~2 mg/mL
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA