product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-LRP1 (N-terminal) antibody produced in rabbit
catalog :
L2295
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, western blot knockout validation
more info or order :
citations: 3
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; 1:1000; fig s1e
Rauch J, Luna G, Guzman E, Audouard M, Challis C, Sibih Y, et al. LRP1 is a master regulator of tau uptake and spread. Nature. 2020;580:381-385 pubmed publisher
Tian Y, Wang C, Chen S, Liu J, Fu Y, Luo Y. Extracellular Hsp90α and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1. J Cell Sci. 2019;132: pubmed publisher
Brifault C, Gilder A, Laudati E, Banki M, Gonias S. Shedding of membrane-associated LDL receptor-related protein-1 from microglia amplifies and sustains neuroinflammation. J Biol Chem. 2017;292:18699-18712 pubmed publisher
product information
Product No. :
L2295
Product Name :
Anti-LRP1 (N-terminal) antibody produced in rabbit
Host :
rabbit
Conjugate :
unconjugated
Antibody Type :
polyclonal
Applications/Description :
Suitable for indirect immunofluorescence: 2-5 μg/mL using rat NRK cells; western blot: 2-4 μg/mL using whole extract of mouse C2C12 cells; western blot: 1-2 μg/mL using whole extract of human U87 cells
Species Reactivity :
rat, mouse, human
Concentration :
~1.0 mg/mL
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA