This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Lectin from Bandeiraea simplicifolia (Griffonia simplicifolia)
catalog :
L2140
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
citations: 69
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:200; loading ...; fig s2
Kanellopoulos A, Koenig J, Huang H, Pyrski M, Millet Q, Lolignier S, et al. Mapping protein interactions of sodium channel NaV1.7 using epitope-tagged gene-targeted mice. EMBO J. 2018;37:427-445 pubmed publisher
  • western blot; human
Sivaraj K, Li R, Albarrán Juárez J, Wang S, Tischner D, Grimm M, et al. Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis. Cardiovasc Res. 2015;108:171-80 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:10
Licht T, Dor Wollman T, Ben Zvi A, Rothe G, Keshet E. Vessel maturation schedule determines vulnerability to neuronal injuries of prematurity. J Clin Invest. 2015;125:1319-28 pubmed publisher
Santini M, Malide D, Hoffman G, Pandey G, D Escamard V, Nomura Kitabayashi A, et al. Tissue-Resident PDGFRα+ Progenitor Cells Contribute to Fibrosis versus Healing in a Context- and Spatiotemporally Dependent Manner. Cell Rep. 2020;30:555-570.e7 pubmed publisher
Yamada M, Fujita Y, Hayano Y, Hayakawa H, Baba K, Mochizuki H, et al. Increased Expression of Fibronectin Leucine-Rich Transmembrane Protein 3 in the Dorsal Root Ganglion Induces Neuropathic Pain in Rats. J Neurosci. 2019;39:7615-7627 pubmed publisher
Fujino N, Brand O, Morgan D, Fujimori T, Grabiec A, Jagger C, et al. Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases. J Exp Med. 2019;216:2184-2201 pubmed publisher
Foxton R, Uhles S, Grüner S, Revelant F, Ullmer C. Efficacy of simultaneous VEGF-A/ANG-2 neutralization in suppressing spontaneous choroidal neovascularization. EMBO Mol Med. 2019;11: pubmed publisher
O Leary O, Canning P, Reid E, Bertelli P, McKeown S, Brines M, et al. The vasoreparative potential of endothelial colony-forming cells in the ischemic retina is enhanced by cibinetide, a non-hematopoietic erythropoietin mimetic. Exp Eye Res. 2019;182:144-155 pubmed publisher
Clark T, Sullender C, Kazmi S, Speetles B, Williamson M, Palmberg D, et al. Artery targeted photothrombosis widens the vascular penumbra, instigates peri-infarct neovascularization and models forelimb impairments. Sci Rep. 2019;9:2323 pubmed publisher
Roa Coria J, Pineda Farias J, Barragán Iglesias P, Quiñonez Bastidas G, Zúñiga Romero Á, Huerta Cruz J, et al. Possible involvement of peripheral TRP channels in the hydrogen sulfide-induced hyperalgesia in diabetic rats. BMC Neurosci. 2019;20:1 pubmed publisher
Scarfe L, Taylor A, Sharkey J, Harwood R, Barrow M, Comenge J, et al. Non-invasive imaging reveals conditions that impact distribution and persistence of cells after in vivo administration. Stem Cell Res Ther. 2018;9:332 pubmed publisher
Mizuma A, Kim J, Kacimi R, Stauderman K, Dunn M, Hebbar S, et al. Microglial calcium release-activated calcium (CRAC) channel inhibition improves outcome from experimental traumatic brain injury and microglia-induced neuronal death. J Neurotrauma. 2018;: pubmed publisher
Plein A, Fantin A, Denti L, Pollard J, Ruhrberg C. Erythro-myeloid progenitors contribute endothelial cells to blood vessels. Nature. 2018;562:223-228 pubmed publisher
Raouf R, Lolignier S, Sexton J, Millet Q, Santana Varela S, Biller A, et al. Inhibition of somatosensory mechanotransduction by annexin A6. Sci Signal. 2018;11: pubmed publisher
Salinas Abarca A, Velázquez Lagunas I, Franco Enzástiga Ú, Torres López J, Rocha Gonzalez H, Granados Soto V. ATF2, but not ATF3, participates in the maintenance of nerve injury-induced tactile allodynia and thermal hyperalgesia. Mol Pain. 2018;14:1744806918787427 pubmed publisher
Liu W, Chen S, Li Z, Lee C, Mirzaa G, Dobyns W, et al. PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia. Genes Dev. 2018;32:763-780 pubmed publisher
Watson Scales S, Kalmar B, Lana Elola E, Gibbins D, La Russa F, Wiseman F, et al. Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration. PLoS Genet. 2018;14:e1007383 pubmed publisher
Tsantoulas C, Denk F, Signore M, Nassar M, Futai K, McMahon S. Mice lacking Kcns1 in peripheral neurons show increased basal and neuropathic pain sensitivity. Pain. 2018;159:1641-1651 pubmed publisher
Hachisuka J, Omori Y, Chiang M, Gold M, Koerber H, Ross S. Wind-up in lamina I spinoparabrachial neurons: a role for reverberatory circuits. Pain. 2018;159:1484-1493 pubmed publisher
Wang D, Tawfik V, Corder G, Low S, Francois A, Basbaum A, et al. Functional Divergence of Delta and Mu Opioid Receptor Organization in CNS Pain Circuits. Neuron. 2018;98:90-108.e5 pubmed publisher
Perez García V, Fineberg E, Wilson R, Murray A, Mazzeo C, Tudor C, et al. Placentation defects are highly prevalent in embryonic lethal mouse mutants. Nature. 2018;555:463-468 pubmed publisher
Fang C, Bian G, Ren P, Xiang J, Song J, Yu C, et al. S1P transporter SPNS2 regulates proper postnatal retinal morphogenesis. FASEB J. 2018;32:3597-3613 pubmed publisher
Dawes J, Weir G, Middleton S, Patel R, Chisholm K, Pettingill P, et al. Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability. Neuron. 2018;97:806-822.e10 pubmed publisher
Kozłowska A, Mikołajczyk A, Majewski M. Distribution and neurochemistry of porcine urinary bladder-projecting sensory neurons in subdomains of the dorsal root ganglia: A quantitative analysis. Ann Anat. 2018;216:36-51 pubmed publisher
Yuan Q, Arkudas A, Horch R, Hammon M, Bleiziffer O, Uder M, et al. Vascularization of the arterio-venous loop in a rat isolation chamber model - Quantification of hypoxia and evaluation of its effects. Tissue Eng Part A. 2017;: pubmed publisher
Weir G, Middleton S, Clark A, Daniel T, Khovanov N, McMahon S, et al. Using an engineered glutamate-gated chloride channel to silence sensory neurons and treat neuropathic pain at the source. Brain. 2017;140:2570-2585 pubmed publisher
Kapelouzou A, Giaglis S, Peroulis M, Katsimpoulas M, Moustardas P, Aravanis C, et al. Overexpression of Toll-Like Receptors 2, 3, 4, and 8 Is Correlated to the Vascular Atherosclerotic Process in the Hyperlipidemic Rabbit Model: The Effect of Statin Treatment. J Vasc Res. 2017;54:156-169 pubmed publisher
Torres Perez J, Santha P, Varga A, Szucs P, Sousa Valente J, Gaál B, et al. Phosphorylated Histone 3 at Serine 10 Identifies Activated Spinal Neurons and Contributes to the Development of Tissue Injury-Associated Pain. Sci Rep. 2017;7:41221 pubmed publisher
Hayano Y, Takasu K, Koyama Y, Yamada M, Ogawa K, Minami K, et al. Dorsal horn interneuron-derived Netrin-4 contributes to spinal sensitization in chronic pain via Unc5B. J Exp Med. 2016;213:2949-2966 pubmed
Nair J, Bezdudnaya T, Zholudeva L, Detloff M, Reier P, Lane M, et al. Histological identification of phrenic afferent projections to the spinal cord. Respir Physiol Neurobiol. 2017;236:57-68 pubmed publisher
Rodríguez C, Sobrino T, Agulla J, Bobo Jiménez V, Ramos Araque M, Duarte J, et al. Neovascularization and functional recovery after intracerebral hemorrhage is conditioned by the Tp53 Arg72Pro single-nucleotide polymorphism. Cell Death Differ. 2017;24:144-154 pubmed publisher
Theodoropoulou S, Copland D, Liu J, Wu J, Gardner P, Ozaki E, et al. Interleukin-33 regulates tissue remodelling and inhibits angiogenesis in the eye. J Pathol. 2017;241:45-56 pubmed publisher
Yazdani A, Khoja Z, Johnstone A, Dale L, Rampakakis E, Wintermark P. Sildenafil Improves Brain Injury Recovery following Term Neonatal Hypoxia-Ischemia in Male Rat Pups. Dev Neurosci. 2016;38:251-263 pubmed
Lieu T, Savage E, Zhao P, Edgington Mitchell L, Barlow N, Bron R, et al. Antagonism of the proinflammatory and pronociceptive actions of canonical and biased agonists of protease-activated receptor-2. Br J Pharmacol. 2016;173:2752-65 pubmed publisher
Casella G, Garzetti L, Gatta A, Finardi A, Maiorino C, Ruffini F, et al. IL4 induces IL6-producing M2 macrophages associated to inhibition of neuroinflammation in vitro and in vivo. J Neuroinflammation. 2016;13:139 pubmed publisher
Tillo M, Charoy C, Schwarz Q, Maden C, Davidson K, Fantin A, et al. 2- and 6-O-sulfated proteoglycans have distinct and complementary roles in cranial axon guidance and motor neuron migration. Development. 2016;143:1907-13 pubmed publisher
Li X, Padhan N, Sjöström E, Roche F, Testini C, Honkura N, et al. VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread. Nat Commun. 2016;7:11017 pubmed publisher
Kim Y, Nam H, Lee J, Park D, Kim C, Yu Y, et al. Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis. Nat Commun. 2016;7:10347 pubmed publisher
Ahn M, Kim J, Park C, Jung K, Moon C, Shin T. Immunohistochemical study of Krüppel-like factor 4 in the spinal cords of rats with experimental autoimmune encephalomyelitis. Acta Histochem. 2015;117:521-7 pubmed publisher
Shaikh H, Lechpammer M, Jensen F, Warfield S, Hansen A, Kosaras B, et al. Increased Brain Perfusion Persists over the First Month of Life in Term Asphyxiated Newborns Treated with Hypothermia: Does it Reflect Activated Angiogenesis?. Transl Stroke Res. 2015;6:224-33 pubmed publisher
Nishiguchi K, Carvalho L, Rizzi M, Powell K, Holthaus S, Azam S, et al. Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179. Nat Commun. 2015;6:6006 pubmed publisher
Yuan Q, Bleiziffer O, Boos A, Sun J, Brandl A, Beier J, et al. PHDs inhibitor DMOG promotes the vascularization process in the AV loop by HIF-1a up-regulation and the preliminary discussion on its kinetics in rat. BMC Biotechnol. 2014;14:112 pubmed publisher
Hollis E, Ishiko N, Tolentino K, Doherty E, Rodríguez M, Calcutt N, et al. A novel and robust conditioning lesion induced by ethidium bromide. Exp Neurol. 2015;265:30-9 pubmed publisher
Luhmann U, Carvalho L, Holthaus S, Cowing J, Greenaway S, Chu C, et al. The severity of retinal pathology in homozygous Crb1rd8/rd8 mice is dependent on additional genetic factors. Hum Mol Genet. 2015;24:128-41 pubmed publisher
Saab S, Buteau B, Leclère L, Bron A, Creuzot Garcher C, Bretillon L, et al. Involvement of plasmalogens in post-natal retinal vascular development. PLoS ONE. 2014;9:e101076 pubmed publisher
Hegyi B, Kornyei Z, Ferenczi S, Fekete R, Kudlik G, Kovacs K, et al. Regulation of mouse microglia activation and effector functions by bone marrow-derived mesenchymal stem cells. Stem Cells Dev. 2014;23:2600-12 pubmed publisher
Leonard A, Thornton E, Vink R. NK1 receptor blockade is ineffective in improving outcome following a balloon compression model of spinal cord injury. PLoS ONE. 2014;9:e98364 pubmed publisher
Horváth E, Woodhams S, Nyilas R, Henstridge C, Kano M, Sakimura K, et al. Heterogeneous presynaptic distribution of monoacylglycerol lipase, a multipotent regulator of nociceptive circuits in the mouse spinal cord. Eur J Neurosci. 2014;39:419-34 pubmed publisher
Zarrinpashneh E, Poggioli T, Sarathchandra P, Lexow J, Monassier L, Terracciano C, et al. Ablation of SGK1 impairs endothelial cell migration and tube formation leading to decreased neo-angiogenesis following myocardial infarction. PLoS ONE. 2013;8:e80268 pubmed publisher
Chu C, Herrmann P, Carvalho L, Liyanage S, Bainbridge J, Ali R, et al. Assessment and in vivo scoring of murine experimental autoimmune uveoretinitis using optical coherence tomography. PLoS ONE. 2013;8:e63002 pubmed publisher
Mansour H, McColm J, Cole L, Weible M, Korlimbinis A, Chan Ling T. Connexin 30 expression and frequency of connexin heterogeneity in astrocyte gap junction plaques increase with age in the rat retina. PLoS ONE. 2013;8:e57038 pubmed publisher
Fudge N, Mearow K. Extracellular matrix-associated gene expression in adult sensory neuron populations cultured on a laminin substrate. BMC Neurosci. 2013;14:15 pubmed publisher
Håkansson J, Ståhlberg A, Wolfhagen Sand F, Gerhardt H, Semb H. N-CAM exhibits a regulatory function in pathological angiogenesis in oxygen induced retinopathy. PLoS ONE. 2011;6:e26026 pubmed publisher
Wrobel L, Schorscher Petcu A, Dupré A, Yoshida M, Nishimori K, Tribollet E. Distribution and identity of neurons expressing the oxytocin receptor in the mouse spinal cord. Neurosci Lett. 2011;495:49-54 pubmed publisher
Fricker F, Lago N, Balarajah S, Tsantoulas C, Tanna S, Zhu N, et al. Axonally derived neuregulin-1 is required for remyelination and regeneration after nerve injury in adulthood. J Neurosci. 2011;31:3225-33 pubmed publisher
Zhao J, Yuan G, Cendan C, Nassar M, Lagerström M, Kullander K, et al. Nociceptor-expressed ephrin-B2 regulates inflammatory and neuropathic pain. Mol Pain. 2010;6:77 pubmed publisher
Zhao J, Lee M, Momin A, Cendan C, Shepherd S, Baker M, et al. Small RNAs control sodium channel expression, nociceptor excitability, and pain thresholds. J Neurosci. 2010;30:10860-71 pubmed publisher
Springer M. Assessment of myocardial angiogenesis and vascularity in small animal models. Methods Mol Biol. 2010;660:149-67 pubmed publisher
Santha P, Oszlács O, Dux M, Dobos I, Jancso G. Inhibition of glucosylceramide synthase reversibly decreases the capsaicin-induced activation and TRPV1 expression of cultured dorsal root ganglion neurons. Pain. 2010;150:103-12 pubmed publisher
Garcia Ortega A, Cañete A, Quinter C, Silberstein L, Piquer Gil M, Alvarez Dolado M, et al. Enhanced hematovascular contribution of SCL 3' enhancer expressing fetal liver cells uncovers their potential to integrate in extramedullary adult niches. Stem Cells. 2010;28:100-12 pubmed publisher
Rennel E, Varey A, Churchill A, Wheatley E, Stewart L, Mather S, et al. VEGF(121)b, a new member of the VEGF(xxx)b family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo. Br J Cancer. 2009;101:1183-93 pubmed publisher
Roudier E, Chapados N, Decary S, Gineste C, Le Bel C, Lavoie J, et al. Angiomotin p80/p130 ratio: a new indicator of exercise-induced angiogenic activity in skeletal muscles from obese and non-obese rats?. J Physiol. 2009;587:4105-19 pubmed publisher
Gautron L, De Smedt V, Layé S. Age-related changes in nestin immunoreactivity in the rat pituitary gland. Neuroendocrinology. 2009;90:19-30 pubmed publisher
Ruvinov E, Sharabani Yosef O, Nagler A, Einbinder T, Feinberg M, Holbova R, et al. Transplantation of genetically engineered cardiac fibroblasts producing recombinant human erythropoietin to repair the infarcted myocardium. Fibrogenesis Tissue Repair. 2008;1:7 pubmed publisher
Baryawno N, Sveinbjörnsson B, Eksborg S, Orrego A, Segerström L, Oqvist C, et al. Tumor-growth-promoting cyclooxygenase-2 prostaglandin E2 pathway provides medulloblastoma therapeutic targets. Neuro Oncol. 2008;10:661-74 pubmed publisher
Xue Q, Sparks D, Streit W. Microglial activation in the hippocampus of hypercholesterolemic rabbits occurs independent of increased amyloid production. J Neuroinflammation. 2007;4:20 pubmed
Kisby G, Standley M, Lu X, O Malley J, Lin B, Muniz J, et al. Molecular networks perturbed in a developmental animal model of brain injury. Neurobiol Dis. 2005;19:108-18 pubmed
Gerhardt H, Golding M, Fruttiger M, Ruhrberg C, Lundkvist A, Abramsson A, et al. VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol. 2003;161:1163-77 pubmed
Hellstrom M, Gerhardt H, Kalén M, Li X, Eriksson U, Wolburg H, et al. Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol. 2001;153:543-53 pubmed
product information
Catalog Number :
L2140
Product Name :
Lectin from Bandeiraea simplicifolia (Griffonia simplicifolia)
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
Isolectin B 4 (BSI-B 4 ), biotin conjugate, lyophilized powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA