This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Lipase from Candida rugosa
catalog :
L1754
citations: 148
Reference
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Xu W, Fu Z, Chen G, Wang Z, Jian Y, Zhang Y, et al. Graphene oxide enabled long-term enzymatic transesterification in an anhydrous gas flux. Nat Commun. 2019;10:2684 pubmed publisher
Pu J, Miura T, Kazama S, Konta Y, Azraini N, Ito E, et al. Weekly variations in norovirus genogroup II genotypes in Japanese oysters. Int J Food Microbiol. 2018;284:48-55 pubmed publisher
Krause J, Merz J. Comparison of enzymatic hydrolysis in a centrifugal partition chromatograph and stirred tank reactor. J Chromatogr A. 2017;1504:64-70 pubmed publisher
Vaquero M, Prieto A, Barriuso J, Martínez M. Expression and properties of three novel fungal lipases/sterol esterases predicted in silico: comparison with other enzymes of the Candida rugosa-like family. Appl Microbiol Biotechnol. 2015;99:10057-67 pubmed publisher
Carrasco C, Marchena A, Holguín Arévalo M, Martin Partido G, Rodriguez A, Paredes S, et al. Anti-inflammatory effects of melatonin in a rat model of caerulein-induced acute pancreatitis. Cell Biochem Funct. 2013;31:585-90 pubmed publisher
Liu W, Zhou F, Zhang X, Li Y, Wang X, Xu X, et al. Preparation of magnetic Fe3O4@SiO2 nanoparticles for immobilization of lipase. J Nanosci Nanotechnol. 2014;14:3068-72 pubmed
Kulka M, Bełtowski J, Klucinski W, Orłowska M, Kołodziejska J, Kleczkowski M. Serum paraoxonase-1 activity of dairy Holstein-Fresian cows in different lactation stages--preliminary study. Pol J Vet Sci. 2014;17:143-7 pubmed
Foddai M, Kasabri V, Petretto G, Azara E, Sias A, Afifi F, et al. In vitro inhibitory effects of Limonium contortirameum and L. virgatum extracts from sardinia on alpha-amylase, alpha-glucosidase and pancreatic lipase. Nat Prod Commun. 2014;9:181-4 pubmed
Rui Wu D, Guang Yu C, Fa Qun H, Zu H, Hong Tao Y, Hong Yin L, et al. Cell cycle characteristics of the pancreas in an animal model of isolated pancreatic trauma. J Trauma Acute Care Surg. 2014;76:784-90 pubmed publisher
Mylonakis M, Xenoulis P, Theodorou K, Siarkou V, Steiner J, Harrus S, et al. Serum canine pancreatic lipase immunoreactivity in experimentally induced and naturally occurring canine monocytic ehrlichiosis (Ehrlichia canis). Vet Microbiol. 2014;169:198-202 pubmed publisher
Gras J. Cetilistat for the treatment of obesity. Drugs Today (Barc). 2013;49:755-9 pubmed publisher
Tiscornia O, Rodríguez R, Sussemil C, Otero G, Negri G, Waisman H, et al. Streptozotocin-induced diabetes, bile-pancreatic secretion and insulo-pancreon-axis interaction. Acta Gastroenterol Latinoam. 2013;43:294-300 pubmed
Karimi K, Shokrollahi B. Lipidemic responses of male broiler chickens to enzyme-supplemented wheat-soybean meal-based diets with various levels of metabolizable energy. Pak J Biol Sci. 2013;16:1295-302 pubmed
Civallero G, De Mari J, Bittar C, Burin M, Giugliani R. Extended use of a selective inhibitor of acid lipase for the diagnosis of Wolman disease and cholesteryl ester storage disease. Gene. 2014;539:154-6 pubmed publisher
Lange L, Hu Y, Zhang H, Xue C, Schmidt E, Tang Z, et al. Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. Am J Hum Genet. 2014;94:233-45 pubmed publisher
Petrushenko V, Sukhodolia S, Falalieieva T, Berehova T. [New approach for treatment of chronic pancreatitis, caused by L-arginine, in rats]. Klin Khir. 2013;:69-72 pubmed
Jiang Y, Cen W, Xing S, Chen J, Xu H, Wen A, et al. Tissue expression pattern and polymorphism of G0S2 gene in porcine. Gene. 2014;539:173-9 pubmed publisher
Tatarkiewicz K, Sablan E, Polizzi C, Villescaz C, Parkes D. Long-term metabolic benefits of exenatide in mice are mediated solely via the known glucagon-like peptide 1 receptor. Am J Physiol Regul Integr Comp Physiol. 2014;306:R490-8 pubmed publisher
Lin Y, Chang P, Chang M, Ni Y. Genetic variants in GCKR and PNPLA3 confer susceptibility to nonalcoholic fatty liver disease in obese individuals. Am J Clin Nutr. 2014;99:869-74 pubmed publisher
Miksztowicz V, Schreier L, McCoy M, Lucero D, Fassio E, Billheimer J, et al. Role of SN1 lipases on plasma lipids in metabolic syndrome and obesity. Arterioscler Thromb Vasc Biol. 2014;34:669-75 pubmed publisher
White M, Boyd J, Horswill A, Nauseef W. Phosphatidylinositol-specific phospholipase C contributes to survival of Staphylococcus aureus USA300 in human blood and neutrophils. Infect Immun. 2014;82:1559-71 pubmed publisher
Xie Y, An J, Yang G, Wu G, Zhang Y, Cui L, et al. Enhanced enzyme kinetic stability by increasing rigidity within the active site. J Biol Chem. 2014;289:7994-8006 pubmed publisher
Singal A, Manjunath H, Yopp A, Beg M, Marrero J, Gopal P, et al. The effect of PNPLA3 on fibrosis progression and development of hepatocellular carcinoma: a meta-analysis. Am J Gastroenterol. 2014;109:325-34 pubmed publisher
Seki Y, Yoshida Y, Ishimine H, Shinozaki Ushiku A, Ito Y, Sumitomo K, et al. Lipase member H is a novel secreted protein selectively upregulated in human lung adenocarcinomas and bronchioloalveolar carcinomas. Biochem Biophys Res Commun. 2014;443:1141-7 pubmed publisher
Mashek D, Greenberg A. Serum TAG analysis differentiates between genetic and obesity-associated NAFLD. Diabetes. 2014;63:42-4 pubmed publisher
Lee S, Liu Q, Hwang B, Lee M. Inhibitory effects of stilbene derivatives from Parthenocissus tricuspidata on adipocyte differentiation and pancreatic lipase. Nat Prod Commun. 2013;8:1439-41 pubmed
Matsui T, Higashimoto Y, Yamagishi S. Laminin receptor mediates anti-inflammatory and anti-thrombogenic effects of pigment epithelium-derived factor in myeloma cells. Biochem Biophys Res Commun. 2014;443:847-51 pubmed publisher
Hirano K, Tanaka T, Ikeda Y, Yamaguchi S, Zaima N, Kobayashi K, et al. Genetic mutations in adipose triglyceride lipase and myocardial up-regulation of peroxisome proliferated activated receptor-γ in patients with triglyceride deposit cardiomyovasculopathy. Biochem Biophys Res Commun. 2014;443:574-9 pubmed publisher
Leança C, Nunes V, Panzoldo N, Zago V, Parra E, Cazita P, et al. Metabolism of plasma cholesterol and lipoprotein parameters are related to a higher degree of insulin sensitivity in high HDL-C healthy normal weight subjects. Cardiovasc Diabetol. 2013;12:173 pubmed publisher
Lin Y, Chiba S, Suzuki A, Yamaguchi S, Nakanishi T, Matsumoto H, et al. Vascular smooth muscle cells isolated from adipose triglyceride lipase-deficient mice exhibit distinct phenotype and phenotypic plasticity. Biochem Biophys Res Commun. 2013;434:534-40 pubmed publisher
Berlemont R, Spee O, Delsaute M, Lara Y, Schuldes J, Simon C, et al. Novel organic solvent-tolerant esterase isolated by metagenomics: insights into the lipase/esterase classification. Rev Argent Microbiol. 2013;45:3-12 pubmed
Nykamp D, Kraus E. Antacid-induced acute pancreatitis. Consult Pharm. 2013;28:247-51 pubmed publisher
Ungerleider N, Bonomi L, Brown M, Schneyer A. Increased activin bioavailability enhances hepatic insulin sensitivity while inducing hepatic steatosis in male mice. Endocrinology. 2013;154:2025-33 pubmed publisher
Cammarota M, Rosa D, Duarte I, Saavedra N, Varesche M, Zaiat M, et al. The effect of enzymatic pre-hydrolysis of dairy wastewater on the granular and immobilized microbial community in anaerobic bioreactors. Environ Technol. 2013;34:417-28 pubmed
Kumar D, Karmase A, Jagtap S, Shekhar R, Bhutani K. Pancreatic lipase inhibitory activity of cassiamin A, a bianthraquinone from Cassia siamea. Nat Prod Commun. 2013;8:195-8 pubmed
Larrieta Carrasco E, León Mimila P, Villarreal Molina T, Villamil Ramírez H, Romero Hidalgo S, Jacobo Albavera L, et al. Association of the I148M/PNPLA3 variant with elevated alanine transaminase levels in normal-weight and overweight/obese Mexican children. Gene. 2013;520:185-8 pubmed publisher
Dong X, Wang G, Zhang G, Ni Z, Suo J, Cui J, et al. The endothelial lipase protein is promising urinary biomarker for diagnosis of gastric cancer. Diagn Pathol. 2013;8:45 pubmed publisher
Mazzucco M, Higa R, Capobianco E, Kurtz M, Jawerbaum A, White V. Saturated fat-rich diet increases fetal lipids and modulates LPL and leptin receptor expression in rat placentas. J Endocrinol. 2013;217:303-15 pubmed publisher
Young S, Zechner R. Biochemistry and pathophysiology of intravascular and intracellular lipolysis. Genes Dev. 2013;27:459-84 pubmed publisher
Badin P, Vila I, Louche K, Mairal A, Marques M, Bourlier V, et al. High-fat diet-mediated lipotoxicity and insulin resistance is related to impaired lipase expression in mouse skeletal muscle. Endocrinology. 2013;154:1444-53 pubmed publisher
Ross L, Xiao X, Lowe M. Identification of amino acids in human colipase that mediate adsorption to lipid emulsions and mixed micelles. Biochim Biophys Acta. 2013;1831:1052-9 pubmed publisher
Schlueter N, Birkenfeld A. How high-density lipoprotein fuels the failing heart. Hypertension. 2013;61:955-7 pubmed publisher
Nakajima H, Ishida T, Satomi Kobayashi S, Mori K, Hara T, Sasaki N, et al. Endothelial lipase modulates pressure overload-induced heart failure through alternative pathway for fatty acid uptake. Hypertension. 2013;61:1002-7 pubmed publisher
Hu M, Li Z, Fang D. A high-carbohydrate diet effects on the A allele of hepatic lipase polymorphism on the apoB100/apoAI ratio in young Chinese males. Adv Clin Exp Med. 2012;21:751-7 pubmed
Lin Cereghino G, Stark C, Kim D, Chang J, Shaheen N, Poerwanto H, et al. The effect of ?-mating factor secretion signal mutations on recombinant protein expression in Pichia pastoris. Gene. 2013;519:311-7 pubmed publisher
van de Weijer T, Havekes B, Bilet L, Hoeks J, Sparks L, Bosma M, et al. Effects of bezafibrate treatment in a patient and a carrier with mutations in the PNPLA2 gene, causing neutral lipid storage disease with myopathy. Circ Res. 2013;112:e51-4 pubmed publisher
Muralidharan M, Buss K, Larrimore K, Segerson N, Kannan L, Mor T. The Arabidopsis thaliana ortholog of a purported maize cholinesterase gene encodes a GDSL-lipase. Plant Mol Biol. 2013;81:565-76 pubmed publisher
Klingenberg R, Gerdes N, Badeau R, Gisterå A, Strodthoff D, Ketelhuth D, et al. Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis. J Clin Invest. 2013;123:1323-34 pubmed publisher
Zierler K, Jaeger D, Pollak N, Eder S, Rechberger G, Radner F, et al. Functional cardiac lipolysis in mice critically depends on comparative gene identification-58. J Biol Chem. 2013;288:9892-904 pubmed publisher
Macpherson R, Ramos S, Vandenboom R, Roy B, Peters S. Skeletal muscle PLIN proteins, ATGL and CGI-58, interactions at rest and following stimulated contraction. Am J Physiol Regul Integr Comp Physiol. 2013;304:R644-50 pubmed publisher
Howaizi M, Chahine M, Haydar F, Jemaa Y, Lapoile E. Cannabis-induced recurrent acute pancreatitis. Acta Gastroenterol Belg. 2012;75:446-7 pubmed
Hall J, Barton L. Mushroom toxicosis in dogs in general practice causing gastroenteritis, ptyalism and elevated serum lipase activity. J Small Anim Pract. 2013;54:275-9 pubmed publisher
Okorokov P, Anikhovskaia I, Iakovleva M, Lazareva S, Melamud A, Meshkov M, et al. [Nutritional factors of inflammation induction or lipid mechanism of intestinal endotoxin transport]. Fiziol Cheloveka. 2012;38:105-12 pubmed
Ventura C, Urich R, Skinner S, Bina R, Chuang K, Van Thiel D, et al. First report of telaprevir-induced pancreatitis. Dig Dis Sci. 2013;58:887-8 pubmed publisher
Tavian D, Missaglia S, Redaelli C, Pennisi E, Invernici G, Wessalowski R, et al. Contribution of novel ATGL missense mutations to the clinical phenotype of NLSD-M: a strikingly low amount of lipase activity may preserve cardiac function. Hum Mol Genet. 2012;21:5318-28 pubmed publisher
Pagnon J, Matzaris M, Stark R, Meex R, Macaulay S, Brown W, et al. Identification and functional characterization of protein kinase A phosphorylation sites in the major lipolytic protein, adipose triglyceride lipase. Endocrinology. 2012;153:4278-89 pubmed publisher
Rigbolt K, Prokhorova T, Akimov V, Henningsen J, Johansen P, Kratchmarova I, et al. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. Sci Signal. 2011;4:rs3 pubmed publisher
Amara S, Barouh N, Lecomte J, Lafont D, Robert S, Villeneuve P, et al. Lipolysis of natural long chain and synthetic medium chain galactolipids by pancreatic lipase-related protein 2. Biochim Biophys Acta. 2010;1801:508-16 pubmed publisher
He S, McPhaul C, Li J, Garuti R, Kinch L, Grishin N, et al. A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis. J Biol Chem. 2010;285:6706-15 pubmed publisher
Berton A, Sebban Kreuzer C, Rouvellac S, Lopez C, Crenon I. Individual and combined action of pancreatic lipase and pancreatic lipase-related proteins 1 and 2 on native versus homogenized milk fat globules. Mol Nutr Food Res. 2009;53:1592-602 pubmed publisher
Schicher M, Kollroser M, Hermetter A. Mapping the lipolytic proteome of adipose tissue using fluorescent suicide inhibitors. Methods Mol Biol. 2009;579:497-511 pubmed publisher
Sookoian S, Castano G, Burgueño A, Gianotti T, Rosselli M, Pirola C. A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity. J Lipid Res. 2009;50:2111-6 pubmed publisher
Saelee P, Wongkham S, Puapairoj A, Khuntikeo N, Petmitr S, Chariyalertsak S, et al. Novel PNLIPRP3 and DOCK8 gene expression and prognostic implications of DNA loss on chromosome 10q25.3 in hepatocellular carcinoma. Asian Pac J Cancer Prev. 2009;10:501-6 pubmed
Griffon N, Jin W, Petty T, Millar J, Badellino K, Saven J, et al. Identification of the active form of endothelial lipase, a homodimer in a head-to-tail conformation. J Biol Chem. 2009;284:23322-30 pubmed publisher
Choi N, Choi J, Kim B, Han Y, Kim J, Lee S, et al. Mixed-substrate (glycerol tributyrate and fibrin) zymography for simultaneous detection of lipolytic and proteolytic enzymes on a single gel. Electrophoresis. 2009;30:2234-7 pubmed publisher
Watanabe A, Fukami T, Nakajima M, Takamiya M, Aoki Y, Yokoi T. Human arylacetamide deacetylase is a principal enzyme in flutamide hydrolysis. Drug Metab Dispos. 2009;37:1513-20 pubmed publisher
Kotronen A, Johansson L, Johansson L, Roos C, Westerbacka J, Hamsten A, et al. A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans. Diabetologia. 2009;52:1056-60 pubmed publisher
Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, et al. Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J Proteome Res. 2009;8:651-61 pubmed publisher
Romeo S, Kozlitina J, Xing C, Pertsemlidis A, Cox D, Pennacchio L, et al. Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat Genet. 2008;40:1461-5 pubmed publisher
Johansson L, Lindblad U, Larsson C, Rastam L, Ridderstrale M. Polymorphisms in the adiponutrin gene are associated with increased insulin secretion and obesity. Eur J Endocrinol. 2008;159:577-83 pubmed publisher
Eydoux C, Spinelli S, Davis T, Walker J, Seitova A, Dhe Paganon S, et al. Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation. Biochemistry. 2008;47:9553-64 pubmed publisher
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Pinheiro R, Soares C, de Castro H, Moraes F, Zanin G. Response surface methodology as an approach to determine optimal activities of lipase entrapped in sol-gel matrix using different vegetable oils. Appl Biochem Biotechnol. 2008;146:203-14 pubmed publisher
Grarup N, Andreasen C, Andersen M, Albrechtsen A, Sandbaek A, Lauritzen T, et al. The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects. J Clin Endocrinol Metab. 2008;93:2294-9 pubmed publisher
Ross M, Crow J. Human carboxylesterases and their role in xenobiotic and endobiotic metabolism. J Biochem Mol Toxicol. 2007;21:187-96 pubmed
Fischer J, Lefèvre C, Morava E, Mussini J, Laforet P, Negre Salvayre A, et al. The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy. Nat Genet. 2007;39:28-30 pubmed
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product information
Catalog Number :
L1754
Product Name :
Lipase from Candida rugosa
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
Type VII, ?700 unit/mg solid
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA