product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-LAMP1 antibody produced in rabbit
catalog :
L1418
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, chicken
application :
western blot, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
citations: 45
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; chicken; 1:1000; fig 4b
Wang J, Ba G, Han Y, Ming S, Wang M, Fu P, et al. Cyclic GMP-AMP synthase is essential for cytosolic double-stranded DNA and fowl adenovirus serotype 4 triggered innate immune responses in chickens. Int J Biol Macromol. 2020;146:497-507 pubmed publisher
  • immunocytochemistry; human; 1:250; loading ...; fig 4b
  • immunocytochemistry; mouse; 1:250; loading ...; fig 8a
Palomo Guerrero M, Fadó R, Casas M, Pérez Montero M, Baena M, Helmer P, et al. Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth. elife. 2019;8: pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 5e
Datta P, Hendrickson B, Brendalen S, Ruffcorn A, Seo S. The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors. J Biol Chem. 2019;294:19119-19136 pubmed publisher
  • immunocytochemistry; rat; 1:300; loading ...; fig 8a
Moreno Blas D, Gorostieta Salas E, Pommer Alba A, Muciño Hernández G, Gerónimo Olvera C, Maciel Barón L, et al. Cortical neurons develop a senescence-like phenotype promoted by dysfunctional autophagy. Aging (Albany NY). 2019;11:6175-6198 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 5c
  • western blot; human; loading ...; fig 3c
Hui L, Soliman M, Geiger N, Miller N, Afghah Z, Lakpa K, et al. Acidifying Endolysosomes Prevented Low-Density Lipoprotein-Induced Amyloidogenesis. J Alzheimers Dis. 2019;67:393-410 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 1b
  • western blot; mouse; 1:1000; loading ...; fig 1a
Shyng C, Macauley S, Dearborn J, Sands M. Widespread Expression of a Membrane-Tethered Version of the Soluble Lysosomal Enzyme Palmitoyl Protein Thioesterase-1. JIMD Rep. 2017;36:85-92 pubmed publisher
  • immunocytochemistry; mouse; 1:100; loading ...; fig 1a
Tan L, Toops K, Lakkaraju A. Protective responses to sublytic complement in the retinal pigment epithelium. Proc Natl Acad Sci U S A. 2016;113:8789-94 pubmed publisher
  • immunocytochemistry; human; 1:300; fig 8
Tognon E, Kobia F, Busi I, Fumagalli A, De Masi F, Vaccari T. Control of lysosomal biogenesis and Notch-dependent tissue patterning by components of the TFEB-V-ATPase axis in Drosophila melanogaster. Autophagy. 2016;12:499-514 pubmed publisher
Szwed M, Torgersen M, Kumari R, Yadava S, Pust S, Iversen T, et al. Biological response and cytotoxicity induced by lipid nanocapsules. J Nanobiotechnology. 2020;18:5 pubmed publisher
Mendsaikhan A, Tooyama I, Bellier J, Serrano G, Sue L, Lue L, et al. Characterization of lysosomal proteins Progranulin and Prosaposin and their interactions in Alzheimer's disease and aged brains: increased levels correlate with neuropathology. Acta Neuropathol Commun. 2019;7:215 pubmed publisher
Xiong J, He J, Xie W, Hinojosa E, Ambati C, Putluri N, et al. Rapid affinity purification of intracellular organelles using a twin strep tag. J Cell Sci. 2019;132: pubmed publisher
Obata Y, Hara Y, Shiina I, Murata T, Tasaki Y, Suzuki K, et al. N822K- or V560G-mutated KIT activation preferentially occurs in lipid rafts of the Golgi apparatus in leukemia cells. Cell Commun Signal. 2019;17:114 pubmed publisher
Sneeggen M, Pedersen N, Campsteijn C, Haugsten E, Stenmark H, Schink K. WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling. Nat Commun. 2019;10:2850 pubmed publisher
Capmany A, Yoshimura A, Kerdous R, Caorsi V, Lescure A, del Nery E, et al. MYO1C stabilizes actin and facilitates the arrival of transport carriers at the Golgi complex. J Cell Sci. 2019;132: pubmed publisher
Baranov M, Bianchi F, Schirmacher A, van Aart M, Maassen S, Muntjewerff E, et al. The Phosphoinositide Kinase PIKfyve Promotes Cathepsin-S-Mediated Major Histocompatibility Complex Class II Antigen Presentation. iScience. 2019;11:160-177 pubmed publisher
Mohapatra G, Gaur P, Mujagond P, Singh M, Rana S, Pratap S, et al. A SUMOylation-dependent switch of RAB7 governs intracellular life and pathogenesis of Salmonella Typhimurium. J Cell Sci. 2019;132: pubmed publisher
Doyle T, Moncorgé O, Bonaventure B, Pollpeter D, Lussignol M, Tauziet M, et al. The interferon-inducible isoform of NCOA7 inhibits endosome-mediated viral entry. Nat Microbiol. 2018;3:1369-1376 pubmed publisher
Takahashi M, Kitaura H, Kakita A, Kakihana T, Katsuragi Y, Nameta M, et al. USP10 Is a Driver of Ubiquitinated Protein Aggregation and Aggresome Formation to Inhibit Apoptosis. iScience. 2018;9:433-450 pubmed publisher
Huang J, Liu P, Wang G. Regulation of mitochondrion-associated cytosolic ribosomes by mammalian mitochondrial ribonuclease T2 (RNASET2). J Biol Chem. 2018;293:19633-19644 pubmed publisher
Weyergang A, Fremstedal A, Skarpen E, Peng Q, Mohamedali K, Eng M, et al. Light-enhanced VEGF121/rGel: A tumor targeted modality with vascular and immune-mediated efficacy. J Control Release. 2018;288:161-172 pubmed publisher
Kim S, Lee Y, Tasaki T, Mun S, Hwang J, Kang M, et al. The N-recognin UBR4 of the N-end rule pathway is targeted to and required for the biogenesis of the early endosome. J Cell Sci. 2018;131: pubmed publisher
Fassio A, Esposito A, Kato M, Saitsu H, Mei D, Marini C, et al. De novo mutations of the ATP6V1A gene cause developmental encephalopathy with epilepsy. Brain. 2018;141:1703-1718 pubmed publisher
Wong Y, Ysselstein D, Krainc D. Mitochondria-lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis. Nature. 2018;554:382-386 pubmed publisher
Real E, Rodrigues L, Cabal G, Enguita F, Mancio Silva L, Mello Vieira J, et al. Plasmodium UIS3 sequesters host LC3 to avoid elimination by autophagy in hepatocytes. Nat Microbiol. 2018;3:17-25 pubmed publisher
Sulheim E, Iversen T, To Nakstad V, Klinkenberg G, Sletta H, Schmid R, et al. Cytotoxicity of Poly(Alkyl Cyanoacrylate) Nanoparticles. Int J Mol Sci. 2017;18: pubmed publisher
Wu Y, Pons V, Goudet A, Panigai L, Fischer A, Herweg J, et al. ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments. Sci Rep. 2017;7:15567 pubmed publisher
Brocard J, Dufour F, Gory Fauré S, Arnoult C, Bosc C, Denarier E, et al. MAP6 interacts with Tctex1 and Cav 2.2/N-type calcium channels to regulate calcium signalling in neurons. Eur J Neurosci. 2017;: pubmed publisher
Shao X, Ding Z, Zhao M, Liu K, Sun H, Chen J, et al. Mammalian Numb protein antagonizes Notch by controlling postendocytic trafficking of the Notch ligand Delta-like 4. J Biol Chem. 2017;292:20628-20643 pubmed publisher
Hong Z, Pedersen N, Wang L, Torgersen M, Stenmark H, Raiborg C. PtdIns3P controls mTORC1 signaling through lysosomal positioning. J Cell Biol. 2017;216:4217-4233 pubmed publisher
Krishnan M, Van Steenwinckel J, Schang A, Yan J, Arnadottir J, Le Charpentier T, et al. Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants. Nat Commun. 2017;8:428 pubmed publisher
Bartolomeo R, Cinque L, De Leonibus C, Forrester A, Salzano A, Monfregola J, et al. mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy. J Clin Invest. 2017;127:3717-3729 pubmed publisher
Chen L, Wang K, Long A, Jia L, Zhang Y, Deng H, et al. Fasting-induced hormonal regulation of lysosomal function. Cell Res. 2017;27:748-763 pubmed publisher
Dingjan I, Linders P, van den Bekerom L, Baranov M, Halder P, ter Beest M, et al. Oxidized phagosomal NOX2 complex is replenished from lysosomes. J Cell Sci. 2017;130:1285-1298 pubmed publisher
Vega Rubin de Celis S, Peña Llopis S, Konda M, Brugarolas J. Multistep regulation of TFEB by MTORC1. Autophagy. 2017;13:464-472 pubmed publisher
Castagnola P, Bellese G, Birocchi F, Gagliani M, Tacchetti C, Cortese K. Identification of an HSP90 modulated multi-step process for ERBB2 degradation in breast cancer cells. Oncotarget. 2016;7:85411-85429 pubmed publisher
Füredi A, Tóth S, Szebényi K, Pape V, Türk D, Kucsma N, et al. Identification and Validation of Compounds Selectively Killing Resistant Cancer: Delineating Cell Line-Specific Effects from P-Glycoprotein-Induced Toxicity. Mol Cancer Ther. 2017;16:45-56 pubmed publisher
Wang Q, Guo W, Hao B, Shi X, Lu Y, Wong C, et al. Mechanistic study of TRPM2-Ca(2+)-CAMK2-BECN1 signaling in oxidative stress-induced autophagy inhibition. Autophagy. 2016;12:1340-54 pubmed publisher
Du W, Su Q, Chen Y, Zhu Y, Jiang D, Rong Y, et al. Kinesin 1 Drives Autolysosome Tubulation. Dev Cell. 2016;37:326-336 pubmed publisher
Su Q, Du W, Ji Q, Xue B, Jiang D, Zhu Y, et al. Vesicle Size Regulates Nanotube Formation in the Cell. Sci Rep. 2016;6:24002 pubmed publisher
Shao X, Liu Y, Yu Q, Ding Z, Qian W, Zhang L, et al. Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Mon1b. Cell Res. 2016;26:593-612 pubmed publisher
Du T, Wang L, Duan C, Lu L, Zhang J, Gao G, et al. GBA deficiency promotes SNCA/α-synuclein accumulation through autophagic inhibition by inactivated PPP2A. Autophagy. 2015;11:1803-20 pubmed publisher
DiGiuseppe S, Keiffer T, Bienkowska Haba M, Luszczek W, Guion L, Muller M, et al. Topography of the Human Papillomavirus Minor Capsid Protein L2 during Vesicular Trafficking of Infectious Entry. J Virol. 2015;89:10442-52 pubmed publisher
Verma S, Mohapatra G, Ahmad S, Rana S, Jain S, Khalsa J, et al. Salmonella Engages Host MicroRNAs To Modulate SUMOylation: a New Arsenal for Intracellular Survival. Mol Cell Biol. 2015;35:2932-46 pubmed publisher
Wang T, Martin S, Papadopulos A, Harper C, Mavlyutov T, Niranjan D, et al. Control of autophagosome axonal retrograde flux by presynaptic activity unveiled using botulinum neurotoxin type a. J Neurosci. 2015;35:6179-94 pubmed publisher
Asundi J, Crocker L, Tremayne J, Chang P, Sakanaka C, Tanguay J, et al. An Antibody-Drug Conjugate Directed against Lymphocyte Antigen 6 Complex, Locus E (LY6E) Provides Robust Tumor Killing in a Wide Range of Solid Tumor Malignancies. Clin Cancer Res. 2015;21:3252-62 pubmed publisher
product information
Product No. :
L1418
Product Name :
Anti-LAMP1 antibody produced in rabbit
Host :
rabbit
Conjugate :
unconjugated
Antibody Type :
polyclonal
Applications/Description :
Suitable for indirect immunofluorescence: 5-10 μg/mL using human HeLa, rat NRK, and mouse NIH3T3 cells
Species Reactivity :
human, rat, mouse
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA