Sari S, Barut B, Ozel A, Söhretoğlu D. Tyrosinase inhibitory effects of Vinca major and its secondary metabolites: Enzyme kinetics and in silico inhibition model of the metabolites validated by pharmacophore modelling. Bioorg Chem. 2019;92:103259 pubmed publisher

Kim J, Lee S, Park S, Park J, Kim Y, Yang S. Slow-Binding Inhibition of Tyrosinase by Ecklonia cava Phlorotannins. Mar Drugs. 2019;17: pubmed publisher

Chang P, Scharfenstein L, Mack B, Wei Q, Gilbert M, Lebar M, et al. Identification of a copper-transporting ATPase involved in biosynthesis of A. flavus conidial pigment. Appl Microbiol Biotechnol. 2019;103:4889-4897 pubmed publisher

Oh T, Jung H, Lee Y, Lee S, Kim G, Kan S, et al. Zerumbone, a Tropical Ginger Sesquiterpene of Zingiber officinale Roscoe, Attenuates α-MSH-Induced Melanogenesis in B16F10 Cells. Int J Mol Sci. 2018;19: pubmed publisher

Radhakrishnan S, Shimmon R, Conn C, Baker A. Development of hydroxylated naphthylchalcones as polyphenol oxidase inhibitors: Synthesis, biochemistry and molecular docking studies. Bioorg Chem. 2015;63:116-22 pubmed publisher

Salleh W, Ahmada F, Yen K, Zulkifli R. Chemical Compositions and Biological Activities of Essential Oils of Beilschmiedia glabra. Nat Prod Commun. 2015;10:1297-300 pubmed

Aerts J, Vandenbroucke R, Dera R, Balusu S, Van Wonterghem E, Moons L, et al. Synthesis and Validation of a Hydroxypyrone-Based, Potent, and Specific Matrix Metalloproteinase-12 Inhibitor with Anti-Inflammatory Activity In Vitro and In Vivo. Mediators Inflamm. 2015;2015:510679 pubmed publisher

Yun H, Kim D, Son S, Ullah S, Kim S, Kim Y, et al. Design, synthesis, and anti-melanogenic effects of (E)-2-benzoyl-3-(substituted phenyl)acrylonitriles. Drug Des Devel Ther. 2015;9:4259-68 pubmed publisher

Radhakrishnan S, Shimmon R, Conn C, Baker A. Design, synthesis and biological evaluation of hydroxy substituted amino chalcone compounds for antityrosinase activity in B16 cells. Bioorg Chem. 2015;62:117-23 pubmed publisher

Lall N, Kishore N, Momtaz S, Hussein A, Naidoo S, Nqephe M, et al. Extract from Ceratonia siliqua Exhibits Depigmentation Properties. Phytother Res. 2015;29:1729-36 pubmed publisher

Paun G, Neagu E, Albu C, Radu G. Inhibitory potential of some Romanian medicinal plants against enzymes linked to neurodegenerative diseases and their antioxidant activity. Pharmacogn Mag. 2015;11:S110-6 pubmed publisher

Mudeppa D, Kumar S, Kokkonda S, White J, Rathod P. Topoisomerase II from Human Malaria Parasites: EXPRESSION, PURIFICATION, AND SELECTIVE INHIBITION. J Biol Chem. 2015;290:20313-24 pubmed publisher

Lee H, Goh M, Kim J, Choi T, Kwang Lee H, Joo Na Y, et al. A systems-biological study on the identification of safe and effective molecular targets for the reduction of ultraviolet B-induced skin pigmentation. Sci Rep. 2015;5:10305 pubmed publisher

Huang H, Ho Y, Lim J, Chang T, Ho C, Chang T. Investigation of the Anti-Melanogenic and Antioxidant Characteristics of Eucalyptus camaldulensis Flower Essential Oil and Determination of Its Chemical Composition. Int J Mol Sci. 2015;16:10470-90 pubmed publisher

Popoola O, Marnewick J, Rautenbach F, Ameer F, Iwuoha E, Hussein A. Inhibition of Oxidative Stress and Skin Aging-Related Enzymes by Prenylated Chalcones and Other Flavonoids from Helichrysum teretifolium. Molecules. 2015;20:7143-55 pubmed publisher

Martín Rodríguez A, Babarro J, Lahoz F, Sansón M, Martín V, Norte M, et al. From broad-spectrum biocides to quorum sensing disruptors and mussel repellents: antifouling profile of alkyl triphenylphosphonium salts. PLoS ONE. 2015;10:e0123652 pubmed publisher

Ogiwara Y, Sugiura M, Watanabe K, Tawara J, Endo E, Maruyama H, et al. Evaluation of the repeated-dose liver, bone marrow and peripheral blood micronucleus and comet assays using kojic acid. Mutat Res Genet Toxicol Environ Mutagen. 2015;780-781:111-6 pubmed publisher

Garcia P, Furlan R. Multiresponse Optimisation Applied to the Development of a TLC Autography for the Detection of Tyrosinase Inhibitors. Phytochem Anal. 2015;26:287-92 pubmed publisher

Jantakee K, Tragoolpua Y. Activities of different types of Thai honey on pathogenic bacteria causing skin diseases, tyrosinase enzyme and generating free radicals. Biol Res. 2015;48:4 pubmed publisher

Zheng Z, Dong X, Yuan K, Lan S, Zhu Q, Wang M, et al. Preparation, characterization, and preliminary antibrowning evaluations of norartocarpetin microemulsions. J Agric Food Chem. 2015;63:1615-21 pubmed publisher

Park M, Kim S, Jeong H, Moon K, Son S, Kim D, et al. Inhibition of melanogenesis by 2-[4-(5-chlorobenzo[d]thiazol-2-yl)phenoxy]-2-methylpropanoic acid (MHY908). Arch Pharm Res. 2015;38:505-11 pubmed publisher

Graf B, Cheng D, Esposito D, Shertel T, Poulev A, Plundrich N, et al. Compounds leached from quinoa seeds inhibit matrix metalloproteinase activity and intracellular reactive oxygen species. Int J Cosmet Sci. 2015;37:212-21 pubmed publisher

Manosroi J, Chankhampan C, Kumguan K, Manosroi W, Manosroi A. In vitro anti-aging activities of extracts from leaves of Ma Kiang (Cleistocalyx nervosum var. paniala). Pharm Biol. 2015;53:862-9 pubmed publisher

Ai N, Welsh W, Santhanam U, Hu H, Lyga J. Novel virtual screening approach for the discovery of human tyrosinase inhibitors. PLoS ONE. 2014;9:e112788 pubmed publisher

Wang K, Li P, Han C, Du L, Liu C, Hu M, et al. Protective effects of kojic acid on the periphery blood and survival of beagle dogs after exposure to a lethal dose of gamma radiation. Radiat Res. 2014;182:666-73 pubmed publisher

Lee Y, Hsiao N, Tseng T, Chen W, Lin H, Leu S, et al. Phage display-mediated discovery of novel tyrosinase-targeting tetrapeptide inhibitors reveals the significance of N-terminal preference of cysteine residues and their functional sulfur atom. Mol Pharmacol. 2015;87:218-30 pubmed publisher

Yoshimori A, Oyama T, Takahashi S, Abe H, Kamiya T, Abe T, et al. Structure-activity relationships of the thujaplicins for inhibition of human tyrosinase. Bioorg Med Chem. 2014;22:6193-200 pubmed publisher

Fu Y, Yang Y, Zhou S, Liu Y, Yuan Y, Li S, et al. Ciprofloxacin containing Mannich base and its copper complex induce antitumor activity via different mechanism of action. Int J Oncol. 2014;45:2092-100 pubmed publisher

Salleh W, Ahmad F, Yen K. Chemical compositions and biological activities of the essential oils of Beilschmiedia madang Blume (Lauraceae). Arch Pharm Res. 2015;38:485-93 pubmed publisher

Sharifi M, Ghadamyari M, Sajedi R, Mahmoodi N. Effects of 4-hexylresorcinol on the phenoloxidase from Hyphantria cunea (Lepidoptera: Arctiidae): In vivo and in vitro studies. Insect Sci. 2015;22:639-50 pubmed publisher

Komori Y, Imai M, Yamauchi T, Higashiyama K, Takahashi N. Effect of p-aminophenols on tyrosinase activity. Bioorg Med Chem. 2014;22:3994-4000 pubmed publisher

Diwakar G, Rana J, Saito L, Vredeveld D, Zemaitis D, Scholten J. Inhibitory effect of a novel combination of Salvia hispanica (chia) seed and Punica granatum (pomegranate) fruit extracts on melanin production. Fitoterapia. 2014;97:164-71 pubmed publisher

Bendaikha S, Gadaut M, Harakat D, Magid A. Acylated flavonol glycosides from the flower of Elaeagnus angustifolia L. Phytochemistry. 2014;103:129-136 pubmed publisher

Lucas S, Gonçalves L, Carvalho L, Correia H, Da Costa E, Guedes R, et al. Optimization of O3-acyl kojic acid derivatives as potent and selective human neutrophil elastase inhibitors. J Med Chem. 2013;56:9802-6 pubmed publisher

Kuijpers T, Gruppen H, Sforza S, van Berkel W, Vincken J. The antibrowning agent sulfite inactivates Agaricus bisporus tyrosinase through covalent modification of the copper-B site. FEBS J. 2013;280:6184-95 pubmed publisher

Misra B, Dey S. TLC-bioautographic evaluation of in vitro anti-tyrosinase and anti-cholinesterase potentials of sandalwood oil. Nat Prod Commun. 2013;8:253-6 pubmed

Kim J, Campbell B, Chan K, Mahoney N, Haff R. Synergism of antifungal activity between mitochondrial respiration inhibitors and kojic acid. Molecules. 2013;18:1564-81 pubmed publisher

Ha Y, Lee H, Park D, Jeong H, Park J, Park Y, et al. Molecular docking studies of (1E,3E,5E)-1,6-Bis(substituted phenyl)hexa-1,3,5-triene and 1,4-Bis(substituted trans-styryl)benzene analogs as novel tyrosinase inhibitors. Biol Pharm Bull. 2013;36:55-65 pubmed

Bae S, Ha Y, Kim J, Park J, Ha T, Park D, et al. A novel synthesized tyrosinase inhibitor: (E)-2-((2,4-dihydroxyphenyl)diazenyl)phenyl 4-methylbenzenesulfonate as an azo-resveratrol analog. Biosci Biotechnol Biochem. 2013;77:65-72 pubmed

Choi S. Inhibitory effects of geranic acid derivatives on melanin biosynthesis. J Cosmet Sci. 2012;63:351-8 pubmed

Kolbe L, Mann T, Gerwat W, Batzer J, Ahlheit S, Scherner C, et al. 4-n-butylresorcinol, a highly effective tyrosinase inhibitor for the topical treatment of hyperpigmentation. J Eur Acad Dermatol Venereol. 2013;27 Suppl 1:19-23 pubmed publisher

Higashi Y, Fujii Y. Determination of kojic acid in a skin-whitening cosmetic by high-performance liquid chromatography coupled with ultraviolet detection after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole. J Cosmet Sci. 2012;63:205-12 pubmed

Ylijoki K, Stryker J. [5 + 2] cycloaddition reactions in organic and natural product synthesis. Chem Rev. 2013;113:2244-66 pubmed publisher

Bae S, Ha Y, Park Y, Park J, Song Y, Ha T, et al. Design, synthesis, and evaluation of (E)-N-substituted benzylidene-aniline derivatives as tyrosinase inhibitors. Eur J Med Chem. 2012;57:383-90 pubmed publisher

Lajis A, Hamid M, Ariff A. Depigmenting effect of Kojic acid esters in hyperpigmented B16F1 melanoma cells. J Biomed Biotechnol. 2012;2012:952452 pubmed publisher

Rizza L, Bonina C, Frasca G, Puglia C. Skin-whitening effects of Mediterranean herbal extracts by in vitro and in vivo models. J Cosmet Sci. 2012;63:311-20 pubmed

Song J, Lee H, Kim Y, Kim S, Kim D, Min K. Discovery of small molecules that inhibit melanogenesis via regulation of tyrosinase expression. Bioorg Med Chem Lett. 2012;22:6943-6 pubmed publisher

Kim J, Kim D, Kim J, Lee S, Kim H, Park H, et al. Recovery of pigmentation following selective photothermolysis in adult zebrafish skin: clinical implications for laser toning treatment of melasma. J Cosmet Laser Ther. 2012;14:277-85 pubmed publisher

Huang J, Liu Y, Ding T, Zhang X, Chen H, Shen C, et al. [Determination of kojic acid in foods using high performance liquid chromatography-tandem mass spectrometry]. Se Pu. 2012;30:578-83 pubmed

Kumar R, Parsad D, Kanwar A, Kaul D. Development of melanocye-keratinocyte co-culture model for controls and vitiligo to assess regulators of pigmentation and melanocytes. Indian J Dermatol Venereol Leprol. 2012;78:599-604 pubmed publisher

Tello E, Castellanos L, Arevalo Ferro C, Duque C. Disruption in quorum-sensing systems and bacterial biofilm inhibition by cembranoid diterpenes isolated from the octocoral Eunicea knighti. J Nat Prod. 2012;75:1637-42 pubmed

Wright J, Clark W, Cain J, Patterson A, Coates C, Nairn J. Effects of known phenoloxidase inhibitors on hemocyanin-derived phenoloxidase from Limulus polyphemus. Comp Biochem Physiol B Biochem Mol Biol. 2012;163:303-8 pubmed publisher

Vontzalidou A, Zoidis G, Chaita E, Makropoulou M, Aligiannis N, Lambrinidis G, et al. Design, synthesis and molecular simulation studies of dihydrostilbene derivatives as potent tyrosinase inhibitors. Bioorg Med Chem Lett. 2012;22:5523-6 pubmed publisher

Kim A, Choi J, Kim J, Yeo S, Choi J, Lee C. Metabolomics-based optimal koji fermentation for tyrosinase inhibition supplemented with Astragalus radix. Biosci Biotechnol Biochem. 2012;76:863-9 pubmed

Zheng Z, Tan H, Wang M. Tyrosinase inhibition constituents from the roots of Morus australis. Fitoterapia. 2012;83:1008-13 pubmed publisher

Cho J, Rho H, Joo Y, Lee C, Lee J, Ahn S, et al. Depigmenting activities of kojic acid derivatives without tyrosinase inhibitory activities. Bioorg Med Chem Lett. 2012;22:4159-62 pubmed publisher

Emami S, Hosseinimehr S, Shahrbandi K, Enayati A, Esmaeeli Z. Synthesis and evaluation of 2(3H)-thiazole thiones as tyrosinase inhibitors. Arch Pharm (Weinheim). 2012;345:629-37 pubmed publisher

Choi H, Kim K, Han J, Choi H, Jin S, Lee E, et al. Kojic acid-induced IL-6 production in human keratinocytes plays a role in its anti-melanogenic activity in skin. J Dermatol Sci. 2012;66:207-15 pubmed publisher

Cho J, Rho H, Baek H, Ahn S, Woo B, Hong Y, et al. Depigmenting activity of new kojic acid derivative obtained as a side product in the synthesis of cinnamate of kojic acid. Bioorg Med Chem Lett. 2012;22:2004-7 pubmed publisher

Gasparetti C, Nordlund E, Jänis J, Buchert J, Kruus K. Extracellular tyrosinase from the fungus Trichoderma reesei shows product inhibition and different inhibition mechanism from the intracellular tyrosinase from Agaricus bisporus. Biochim Biophys Acta. 2012;1824:598-607 pubmed publisher

Thanigaimalai P, Rao E, Lee K, Sharma V, Roh E, Kim Y, et al. Structure-activity relationship of naphthaldehydethiosemicarbazones in melanogenesis inhibition. Bioorg Med Chem Lett. 2012;22:886-9 pubmed publisher

Hu X, Wu J, Wang M, Yu M, Zhao Q, Wang H, et al. 2-Arylbenzofuran, flavonoid, and tyrosinase inhibitory constituents of Morus yunnanensis. J Nat Prod. 2012;75:82-7 pubmed publisher

Goh M, Park J, Bae J, Kim D, Kim H, Na Y. Effects of ortho-dihydroxyisoflavone derivatives from Korean fermented soybean paste on melanogenesis in B16 melanoma cells and human skin equivalents. Phytother Res. 2012;26:1107-12 pubmed publisher

Ahn S, Rho H, Baek H, Joo Y, Hong Y, Shin S, et al. Inhibitory activity of novel kojic acid derivative containing trolox moiety on melanogenesis. Bioorg Med Chem Lett. 2011;21:7466-9 pubmed publisher

Thanigaimalai P, Lee K, Sharma V, Joo C, Cho W, Roh E, et al. Structural requirement of phenylthiourea analogs for their inhibitory activity of melanogenesis and tyrosinase. Bioorg Med Chem Lett. 2011;21:6824-8 pubmed publisher

Yi W, Dubois C, Yahiaoui S, Haudecoeur R, Belle C, Song H, et al. Refinement of arylthiosemicarbazone pharmacophore in inhibition of mushroom tyrosinase. Eur J Med Chem. 2011;46:4330-5 pubmed publisher

Thanigaimalai P, Lee K, Sharma V, Roh E, Kim Y, Jung S. Ketonethiosemicarbazones: structure-activity relationships for their melanogenesis inhibition. Bioorg Med Chem Lett. 2011;21:3527-30 pubmed publisher

Yu L, Hu W, Ding G, Li R, Wei J, Zou Z, et al. Gusanlungionosides A-D, potential tyrosinase inhibitors from Arcangelisia gusanlung. J Nat Prod. 2011;74:1009-14 pubmed publisher

Ha Y, Park J, Park Y, Park D, Choi Y, Kim J, et al. Synthesis and biological activity of hydroxy substituted phenyl-benzo[d]thiazole analogues for antityrosinase activity in B16 cells. Bioorg Med Chem Lett. 2011;21:2445-9 pubmed publisher

Takahashi T, Miyazawa M. Synthesis and structure-activity relationships of phenylpropanoid amides of serotonin on tyrosinase inhibition. Bioorg Med Chem Lett. 2011;21:1983-6 pubmed publisher

Tajima R, Oozeki H, Muraoka S, Tanaka S, Motegi Y, Nihei H, et al. Synthesis and evaluation of bibenzyl glycosides as potent tyrosinase inhibitors. Eur J Med Chem. 2011;46:1374-81 pubmed publisher

Fang Y, Chen Y, Feng G, Ma L. Benzyl benzoates: New phlorizin analogs as mushroom tyrosinase inhibitors. Bioorg Med Chem. 2011;19:1167-71 pubmed publisher

Peralta M, Ortega M, Agnese A, Cabrera J. Prenylated flavanones with anti-tyrosinase activity from Dalea boliviana. J Nat Prod. 2011;74:158-62 pubmed publisher

Jacobsen J, Fullagar J, Miller M, Cohen S. Identifying chelators for metalloprotein inhibitors using a fragment-based approach. J Med Chem. 2011;54:591-602 pubmed publisher

Burnett C, Bergfeld W, Belsito D, Hill R, Klaassen C, Liebler D, et al. Final report of the safety assessment of Kojic acid as used in cosmetics. Int J Toxicol. 2010;29:244S-73 pubmed publisher

Fujimoto A, Shingai Y, Nakamura M, Maekawa T, Sone Y, Masuda T. A novel ring-expanded product with enhanced tyrosinase inhibitory activity from classical Fe-catalyzed oxidation of rosmarinic acid, a potent antioxidative Lamiaceae polyphenol. Bioorg Med Chem Lett. 2010;20:7393-6 pubmed publisher

Takahashi S, Kamiya T, Saeki K, Nezu T, Takeuchi S, Takasawa R, et al. Structural insights into the hot spot amino acid residues of mushroom tyrosinase for the bindings of thujaplicins. Bioorg Med Chem. 2010;18:8112-8 pubmed publisher

Rho H, Ahn S, Yoo D, Kim M, Cho D, Cho J. Kojyl thioether derivatives having both tyrosinase inhibitory and anti-inflammatory properties. Bioorg Med Chem Lett. 2010;20:6569-71 pubmed publisher

Delogu G, Podda G, Corda M, Fadda M, Fais A, Era B. Synthesis and biological evaluation of a novel series of bis-salicylaldehydes as mushroom tyrosinase inhibitors. Bioorg Med Chem Lett. 2010;20:6138-40 pubmed publisher

Choi J, Bae S, Ha Y, No J, Lee E, Lee J, et al. A newly synthesized, potent tyrosinase inhibitor: 5-(6-hydroxy-2-naphthyl)-1,2,3-benzenetriol. Bioorg Med Chem Lett. 2010;20:4882-4 pubmed publisher

Hwang S, Choi S, Lee J, Kim S, In J, Ha S, et al. Identification of a potent and noncytotoxic inhibitor of melanin production. Bioorg Med Chem. 2010;18:5602-9 pubmed publisher

Wang H, Chen C, Chen C, Ho M, Chou Y, Chang H, et al. (-)-N-Formylanonaine from Michelia alba as a human tyrosinase inhibitor and antioxidant. Bioorg Med Chem. 2010;18:5241-7 pubmed publisher

Lam K, Syahida A, Ul Haq Z, Abdul Rahman M, Lajis N. Synthesis and biological activity of oxadiazole and triazolothiadiazole derivatives as tyrosinase inhibitors. Bioorg Med Chem Lett. 2010;20:3755-9 pubmed publisher

Ghani U, Ullah N. New potent inhibitors of tyrosinase: novel clues to binding of 1,3,4-thiadiazole-2(3H)-thiones, 1,3,4-oxadiazole-2(3H)-thiones, 4-amino-1,2,4-triazole-5(4H)-thiones, and substituted hydrazides to the dicopper active site. Bioorg Med Chem. 2010;18:4042-8 pubmed publisher

Nakashima S, Matsuda H, Oda Y, Nakamura S, Xu F, Yoshikawa M. Melanogenesis inhibitors from the desert plant Anastatica hierochuntica in B16 melanoma cells. Bioorg Med Chem. 2010;18:2337-45 pubmed publisher

Seo W, Ryu Y, Curtis Long M, Lee C, Ryu H, Jang K, et al. Evaluation of anti-pigmentary effect of synthetic sulfonylamino chalcone. Eur J Med Chem. 2010;45:2010-7 pubmed publisher

Thanigaimalai P, Lee K, Bang S, Lee J, Yun C, Roh E, et al. Evaluation of 3,4-dihydroquinazoline-2(1H)-thiones as inhibitors of alpha-MSH-induced melanin production in melanoma B16 cells. Bioorg Med Chem. 2010;18:1555-62 pubmed publisher

Thanigaimalai P, Lee K, Bang S, Lee J, Yun C, Roh E, et al. Inhibitory effect of novel tetrahydropyrimidine-2(1H)-thiones on melanogenesis. Bioorg Med Chem. 2010;18:1135-42 pubmed publisher

Noh J, Kwak S, Seo H, Seo J, Kim B, Lee Y. Kojic acid-amino acid conjugates as tyrosinase inhibitors. Bioorg Med Chem Lett. 2009;19:5586-9 pubmed publisher

Matsuda H, Nakashima S, Oda Y, Nakamura S, Yoshikawa M. Melanogenesis inhibitors from the rhizomes of Alpinia officinarum in B16 melanoma cells. Bioorg Med Chem. 2009;17:6048-53 pubmed publisher

Ngoc T, Lee I, Ha D, Kim H, Min B, Bae K. Tyrosinase-inhibitory constituents from the twigs of Cinnamomum cassia. J Nat Prod. 2009;72:1205-8 pubmed publisher

Yamazaki Y, Kawano Y, Yamanaka A, Maruyama S. N-[(Dihydroxyphenyl)acyl]serotonins as potent inhibitors of tyrosinase from mouse and human melanoma cells. Bioorg Med Chem Lett. 2009;19:4178-82 pubmed publisher

Bora Tatar G, Dayangac Erden D, Demir A, Dalkara S, Yelekçi K, Erdem Yurter H. Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies. Bioorg Med Chem. 2009;17:5219-28 pubmed publisher

Ng L, Ko H, Lu T. Potential antioxidants and tyrosinase inhibitors from synthetic polyphenolic deoxybenzoins. Bioorg Med Chem. 2009;17:4360-6 pubmed publisher

Lee K, Ab Aziz F, Syahida A, Abas F, Shaari K, Israf D, et al. Synthesis and biological evaluation of curcumin-like diarylpentanoid analogues for anti-inflammatory, antioxidant and anti-tyrosinase activities. Eur J Med Chem. 2009;44:3195-200 pubmed publisher

Fassihi A, Abedi D, Saghaie L, Sabet R, Fazeli H, Bostaki G, et al. Synthesis, antimicrobial evaluation and QSAR study of some 3-hydroxypyridine-4-one and 3-hydroxypyran-4-one derivatives. Eur J Med Chem. 2009;44:2145-57 pubmed publisher

Tocco G, Fais A, Meli G, Begala M, Podda G, Fadda M, et al. PEG-immobilization of cardol and soluble polymer-supported synthesis of some cardol-coumarin derivatives: preliminary evaluation of their inhibitory activity on mushroom tyrosinase. Bioorg Med Chem Lett. 2009;19:36-9 pubmed publisher

Kang S, Kim H, Jin C, Lee Y. Synthesis of tyrosinase inhibitory (4-oxo-4H-pyran-2-yl)acrylic acid ester derivatives. Bioorg Med Chem Lett. 2009;19:188-91 pubmed publisher

Ko H, Chang W, Lu T. Antityrosinase and antioxidant effects of ent-kaurane diterpenes from leaves of Broussonetia papyrifera. J Nat Prod. 2008;71:1930-3 pubmed publisher

Oozeki H, Tajima R, Nihei K. Molecular design of potent tyrosinase inhibitors having the bibenzyl skeleton. Bioorg Med Chem Lett. 2008;18:5252-4 pubmed publisher

Chen Q, Youn U, Min B, Bae K. Pyronane monoterpenoids from the fruit of Gardenia jasminoides. J Nat Prod. 2008;71:995-9 pubmed publisher

Criton M, Le Mellay Hamon V. Analogues of N-hydroxy-N'-phenylthiourea and N-hydroxy-N'-phenylurea as inhibitors of tyrosinase and melanin formation. Bioorg Med Chem Lett. 2008;18:3607-10 pubmed publisher

Wu B, Chen J, Qu H, Cheng Y. Complex sesquiterpenoids with tyrosinase inhibitory activity from the leaves of Chloranthus tianmushanensis. J Nat Prod. 2008;71:877-80 pubmed publisher

Chang S, Bray S, Li Z, Zarnescu D, He C, Jin P, et al. Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila. Nat Chem Biol. 2008;4:256-63 pubmed publisher

Liu J, Yi W, Wan Y, Ma L, Song H. 1-(1-Arylethylidene)thiosemicarbazide derivatives: a new class of tyrosinase inhibitors. Bioorg Med Chem. 2008;16:1096-102 pubmed

Germanas J, Wang S, Miner A, Hao W, Ready J. Discovery of small-molecule inhibitors of tyrosinase. Bioorg Med Chem Lett. 2007;17:6871-5 pubmed

Casañola Martin G, Marrero Ponce Y, Khan M, Ather A, Khan K, Torrens F, et al. Dragon method for finding novel tyrosinase inhibitors: Biosilico identification and experimental in vitro assays. Eur J Med Chem. 2007;42:1370-81 pubmed

Karioti A, Protopappa A, Megoulas N, Skaltsa H. Identification of tyrosinase inhibitors from Marrubium velutinum and Marrubium cylleneum. Bioorg Med Chem. 2007;15:2708-14 pubmed

Jun N, Hong G, Jun K. Synthesis and evaluation of 2',4',6'-trihydroxychalcones as a new class of tyrosinase inhibitors. Bioorg Med Chem. 2007;15:2396-402 pubmed

Bentley R. From miso, saké and shoyu to cosmetics: a century of science for kojic acid. Nat Prod Rep. 2006;23:1046-62 pubmed

Song S, Lee H, Jin Y, Ha Y, Bae S, Chung H, et al. Syntheses of hydroxy substituted 2-phenyl-naphthalenes as inhibitors of tyrosinase. Bioorg Med Chem Lett. 2007;17:461-4 pubmed

Emami S, Hosseinimehr S, Taghdisi S, Akhlaghpoor S. Kojic acid and its manganese and zinc complexes as potential radioprotective agents. Bioorg Med Chem Lett. 2007;17:45-8 pubmed

Likhitwitayawuid K, Sornsute A, Sritularak B, Ploypradith P. Chemical transformations of oxyresveratrol (trans-2,4,3',5'-tetrahydroxystilbene) into a potent tyrosinase inhibitor and a strong cytotoxic agent. Bioorg Med Chem Lett. 2006;16:5650-3 pubmed

Cho S, Roh J, Sun W, Kim S, Park K. N-Benzylbenzamides: a new class of potent tyrosinase inhibitors. Bioorg Med Chem Lett. 2006;16:2682-4 pubmed

Okombi S, Rival D, Bonnet S, Mariotte A, Perrier E, Boumendjel A. Analogues of N-hydroxycinnamoylphenalkylamides as inhibitors of human melanocyte-tyrosinase. Bioorg Med Chem Lett. 2006;16:2252-5 pubmed

Casañola Martin G, Khan M, Marrero Ponce Y, Ather A, Sultankhodzhaev M, Torrens F. New tyrosinase inhibitors selected by atomic linear indices-based classification models. Bioorg Med Chem Lett. 2006;16:324-30 pubmed

Burdock G, Soni M, Carabin I. Evaluation of health aspects of kojic acid in food. Regul Toxicol Pharmacol. 2001;33:80-101 pubmed

Tamura T, Mitsumori K, Onodera H, Takahashi M, Funakoshi T, Yasuhara K, et al. Time course observation of thyroid proliferative lesions and serum levels of related hormones in rats treated with kojic acid after DHPN initiation. J Toxicol Sci. 1999;24:145-55 pubmed

Novotny L, Rauko P, Abdel Hamid M, Vachalkova A. Kojic acid--a new leading molecule for a preparation of compounds with an anti-neoplastic potential. Neoplasma. 1999;46:89-92 pubmed

Fujimoto N, Onodera H, Mitsumori K, Tamura T, Maruyama S, Ito A. Changes in thyroid function during development of thyroid hyperplasia induced by kojic acid in F344 rats. Carcinogenesis. 1999;20:1567-71 pubmed

Ellis D, Tan A, Ellis C. Superficial micropeels: glycolic acid and alpha-hydroxy acid with kojic acid. Facial Plast Surg. 1995;11:15-21 pubmed