This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Kallikrein from human plasma
catalog :
K2638
citations: 69
Reference
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Portelli M, Siedlinski M, Stewart C, Postma D, Nieuwenhuis M, Vonk J, et al. Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels. FASEB J. 2014;28:923-34 pubmed publisher
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Schmitt M, Renne T, Scorilas A. The kallikreins: old proteases with new clinical potentials. Thromb Haemost. 2013;110:396-8 pubmed publisher
Björkqvist J, Jämsä A, Renne T. Plasma kallikrein: the bradykinin-producing enzyme. Thromb Haemost. 2013;110:399-407 pubmed publisher
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Sheffield C, Crippen T, Poole T, Beier R. Destruction of single-species biofilms of Escherichia coli or Klebsiella pneumoniae subsp. pneumoniae by dextranase, lactoferrin, and lysozyme. Int Microbiol. 2012;15:185-9 pubmed
Lamy S, Wilmart J, Hein T, Scheiden R, Capesius C. [Prostate cancer in Luxembourg from 1982 to 2006. Incidence and mortality. Survival of a hospital cohort]. Bull Soc Sci Med Grand Duche Luxemb. 2013;:6-19 pubmed
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Chen Q, Lee T, Kumar A, Min J, Choi J. Analysis of nanoscale protein film consisting of lactoferrin/11-MUA bilayers for bioelectronic device. J Biomed Nanotechnol. 2013;9:849-55 pubmed
Yeap S, Omar A, Ho W, Beh B, Ali A, Alitheen N. Rhaphidophora korthalsii modulates peripheral blood natural killer cell proliferation, cytokine secretion and cytotoxicity. BMC Complement Altern Med. 2013;13:145 pubmed publisher
Yang W, Han W, Ye S, Liu D, Wu J, Liu H, et al. Fibroblast activation protein-? promotes ovarian cancer cell proliferation and invasion via extracellular and intracellular signaling mechanisms. Exp Mol Pathol. 2013;95:105-10 pubmed publisher
Tietge U, Groen A. Role the TICE?: advancing the concept of transintestinal cholesterol excretion. Arterioscler Thromb Vasc Biol. 2013;33:1452-3 pubmed publisher
Suzuki M, Yamanoi A, Machino Y, Kobayashi E, Fukuchi K, Tsukimoto M, et al. Cleavage of the interchain disulfide bonds in rituximab increases its affinity for FcγRIIIA. Biochem Biophys Res Commun. 2013;436:519-24 pubmed publisher
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Camaschella C. Treating iron overload. N Engl J Med. 2013;368:2325-7 pubmed publisher
Pereira M, Byrne B, Nguyen T, Lewis D, Atwill E. The occurrence of subtilase-cytotoxin-encoding genes in environmental Escherichia coli isolated from a Northern California estuary. Can J Microbiol. 2013;59:437-41 pubmed publisher
Hogendorf A, Stańczyk Przyłuska A, Sieniwicz Luzeńczyk K, Wiszniewska M, Arendarczyk J, Banasik M, et al. Is there any association between secretory IgA and lactoferrin concentration in mature human milk and food allergy in breastfed children. Med Wieku Rozwoj. 2013;17:47-52 pubmed
Stolp J, Marino E, Batten M, Sierro F, Cox S, Grey S, et al. Intrinsic molecular factors cause aberrant expansion of the splenic marginal zone B cell population in nonobese diabetic mice. J Immunol. 2013;191:97-109 pubmed publisher
Bubber P, Chauhan A, Sharma A, Bubber N, Bansal D. Effect of thyroxine on fibrinolytic system in rat. Indian J Physiol Pharmacol. 2012;56:267-72 pubmed
Gerhardt E, Masso M, Paton A, Paton J, Zotta E, Ibarra C. Inhibition of water absorption and selective damage to human colonic mucosa are induced by subtilase cytotoxin produced by Escherichia coli O113:H21. Infect Immun. 2013;81:2931-7 pubmed publisher
Endow J, Inoue K. Stable complex formation of thylakoidal processing peptidase and PGRL1. FEBS Lett. 2013;587:2226-31 pubmed publisher
Diener H, Foerch C, Riess H, Rother J, Schroth G, Weber R. Treatment of acute ischaemic stroke with thrombolysis or thrombectomy in patients receiving anti-thrombotic treatment. Lancet Neurol. 2013;12:677-88 pubmed publisher
Martin A, Lord S, Verry H, Stockler M, Emery J. Risk assessment to guide prostate cancer screening decisions: a cost-effectiveness analysis. Med J Aust. 2013;198:546-50 pubmed
Rychetnik L, Carter S, Barratt A, Irwig L. Expanding the evidence on cancer screening: the value of scientific, social and ethical perspectives. Med J Aust. 2013;198:536-9 pubmed
Hugosson J, Carlsson S. The dilemmas of prostate cancer screening. Med J Aust. 2013;198:528-9 pubmed
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Matsuoka H, Kurata T, Okamoto I, Kaneda H, Tanaka K, Nakagawa K. Clinical response to crizotinib retreatment after acquisition of drug resistance. J Clin Oncol. 2013;31:e322-3 pubmed publisher
Ohnishi Y, Yamada T, Kurihara K, Tanaka I, Sakiyama F, Masaki T, et al. Neutron and X-ray crystallographic analysis of Achromobacter protease I at pD 8.0: protonation states and hydration structure in the free-form. Biochim Biophys Acta. 2013;1834:1642-7 pubmed publisher
Ero M, Ng C, Mihailovski T, Harvey N, Lewis B. A pilot study on the serum pharmacokinetics of nattokinase in humans following a single, oral, daily dose. Altern Ther Health Med. 2013;19:16-9 pubmed
Xu Z, Chen X, Peng C, Liu E, Li Y, Li C, et al. The expression and clinical significance of Omi/Htra2 in hepatocellular carcinoma. Hepatogastroenterology. 2013;60:6-13 pubmed
Feener E, Zhou Q, Fickweiler W. Role of plasma kallikrein in diabetes and metabolism. Thromb Haemost. 2013;110:434-41 pubmed publisher
Nagashima T, Li Q, Clementi C, Lydon J, DeMayo F, Matzuk M. BMPR2 is required for postimplantation uterine function and pregnancy maintenance. J Clin Invest. 2013;123:2539-50 pubmed publisher
Akhatib B, Onnerfjord P, Gawri R, Ouellet J, Jarzem P, Heinegard D, et al. Chondroadherin fragmentation mediated by the protease HTRA1 distinguishes human intervertebral disc degeneration from normal aging. J Biol Chem. 2013;288:19280-7 pubmed publisher
Friis S, Uzzun Sales K, Godiksen S, Peters D, Lin C, Vogel L, et al. A matriptase-prostasin reciprocal zymogen activation complex with unique features: prostasin as a non-enzymatic co-factor for matriptase activation. J Biol Chem. 2013;288:19028-39 pubmed publisher
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Baeriswyl V, Calzavarini S, Gerschheimer C, Diderich P, Angelillo Scherrer A, Heinis C. Development of a selective peptide macrocycle inhibitor of coagulation factor XII toward the generation of a safe antithrombotic therapy. J Med Chem. 2013;56:3742-6 pubmed publisher
Pathak M, Wong S, Dreveny I, Emsley J. Structure of plasma and tissue kallikreins. Thromb Haemost. 2013;110:423-33 pubmed publisher
Millers E, Johnson L, Birrell G, Masci P, Lavin M, de Jersey J, et al. The structure of human microplasmin in complex with textilinin-1, an aprotinin-like inhibitor from the Australian brown snake. PLoS ONE. 2013;8:e54104 pubmed publisher
Liu J, Clermont A, Gao B, Feener E. Intraocular hemorrhage causes retinal vascular dysfunction via plasma kallikrein. Invest Ophthalmol Vis Sci. 2013;54:1086-94 pubmed publisher
Iarovaia G, Neshkova E, Blokhina T, Kochergin S, Vorob eva I, Gigineishvili D. [Kallikrein-kinin system as a target for diabetic retinopathy treatment]. Vestn Oftalmol. 2012;128:78-81 pubmed
Renne T, Gruber A. Plasma kallikrein: novel functions for an old protease. Thromb Haemost. 2012;107:1012-3 pubmed publisher
Chen S, Morales Sanfrutos J, Angelini A, Cutting B, Heinis C. Structurally diverse cyclisation linkers impose different backbone conformations in bicyclic peptides. Chembiochem. 2012;13:1032-8 pubmed publisher
Baeriswyl V, Rapley H, Pollaro L, Stace C, Teufel D, Walker E, et al. Bicyclic peptides with optimized ring size inhibit human plasma kallikrein and its orthologues while sparing paralogous proteases. ChemMedChem. 2012;7:1173-6 pubmed publisher
Bird J, Smith P, Wang X, Schumacher W, Barbera F, Revelli J, et al. Effects of plasma kallikrein deficiency on haemostasis and thrombosis in mice: murine ortholog of the Fletcher trait. Thromb Haemost. 2012;107:1141-50 pubmed publisher
Kolte D, Bryant J, Gibson G, Wang J, Shariat Madar Z. PF-04886847 (an inhibitor of plasma kallikrein) attenuates inflammatory mediators and activation of blood coagulation in rat model of lipopolysaccharide (LPS)-induced sepsis. Cardiovasc Hematol Agents Med Chem. 2012;10:154-66 pubmed
Saito A. Diversity of human plasma protein C inhibitor. Thromb Res. 2012;130:661-6 pubmed publisher
Heinis C. Bicyclic peptide antagonists derived from genetically encoded combinatorial libraries. Chimia (Aarau). 2011;65:677-9 pubmed
Earl S, Richards R, Johnson L, Flight S, Anderson S, Liao A, et al. Identification and characterisation of Kunitz-type plasma kallikrein inhibitors unique to Oxyuranus sp. snake venoms. Biochimie. 2012;94:365-73 pubmed publisher
Clermont A, Chilcote T, Kita T, Liu J, Riva P, Sinha S, et al. Plasma kallikrein mediates retinal vascular dysfunction and induces retinal thickening in diabetic rats. Diabetes. 2011;60:1590-8 pubmed publisher
Liu J, Gao B, Clermont A, Blair P, Chilcote T, Sinha S, et al. Hyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikrein. Nat Med. 2011;17:206-10 pubmed publisher
Austin H, De Staercke C, Lally C, Bezemer I, Rosendaal F, Hooper W. New gene variants associated with venous thrombosis: a replication study in White and Black Americans. J Thromb Haemost. 2011;9:489-95 pubmed publisher
Kolte D, Bryant J, Holsworth D, Wang J, Akbari P, Gibson G, et al. Biochemical characterization of a novel high-affinity and specific plasma kallikrein inhibitor. Br J Pharmacol. 2011;162:1639-49 pubmed publisher
Banerji A. Current treatment of hereditary angioedema: An update on clinical studies. Allergy Asthma Proc. 2010;31:398-406 pubmed publisher
López Lera A, Favier B, de la Cruz R, Garrido S, Drouet C, Lopez Trascasa M. A new case of homozygous C1-inhibitor deficiency suggests a role for Arg378 in the control of kinin pathway activation. J Allergy Clin Immunol. 2010;126:1307-10.e3 pubmed publisher
Stolz L, Horn P. Ecallantide: a plasma kallikrein inhibitor for the treatment of acute attacks of hereditary angioedema. Drugs Today (Barc). 2010;46:547-55 pubmed publisher
Dellalibera Joviliano R, Joviliano E, Evora P. Determination of kininogens levels and kallikrein/kininase II activities in patients with thromboangiitis obliterans. Scand J Immunol. 2010;72:128-33 pubmed publisher
Feener E. Plasma kallikrein and diabetic macular edema. Curr Diab Rep. 2010;10:270-5 pubmed publisher
Dellalibera Joviliano R, Reis M, Donadi E. The kinin system in patients with systemic lupus erythematosus exhibiting mucocutaneous lesions: a clinical study. Scand J Immunol. 2010;71:292-7 pubmed publisher
Kaplan A, Joseph K. The bradykinin-forming cascade and its role in hereditary angioedema. Ann Allergy Asthma Immunol. 2010;104:193-204 pubmed publisher
Stoop A, Joshi R, Eggers C, Craik C. Analysis of an engineered plasma kallikrein inhibitor and its effect on contact activation. Biol Chem. 2010;391:425-33 pubmed publisher
Almeida S, Barros C, Moraes M, Russo F, Haro A, Rosa T, et al. Plasma Kallikrein and Angiotensin I-converting enzyme N- and C-terminal domain activities are modulated by the insertion/deletion polymorphism. Neuropeptides. 2010;44:139-43 pubmed publisher
McRae B, Kurachi K, Heimark R, Fujikawa K, Davie E, Powers J. Mapping the active sites of bovine thrombin, factor IXa, factor Xa, factor XIa, factor XIIa, plasma kallikrein, and trypsin with amino acid and peptide thioesters: development of new sensitive substrates. Biochemistry. 1981;20:7196-206 pubmed
Heimark R, Davie E. Bovine and human plasma prekallikrein. Methods Enzymol. 1981;80 Pt C:157-72 pubmed
Silverberg M, Kaplan A. Prekallikrein. Methods Enzymol. 1988;163:85-95 pubmed
Seidah N, Ladenheim R, Mbikay M, Hamelin J, Lutfalla G, Rougeon F, et al. The cDNA structure of rat plasma kallikrein. DNA. 1989;8:563-74 pubmed
Tsuda Y, Teno N, Okada Y, Wanaka K, Bohgaki M, Hijikata Okunomiya A, et al. Synthesis of tripeptide chloromethyl ketones and examination of their inhibitory effects on plasmin and plasma kallikrein. Chem Pharm Bull (Tokyo). 1989;37:3108-11 pubmed
product information
Catalog Number :
K2638
Product Name :
Kallikrein from human plasma
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
buffered aqueous solution, ?5 units/mg protein
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA