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product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Ketoprofen
catalog :
K1751
citations: 179
Reference
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Kolacz M, Karlinski M, Walerzak K, Trzebicki J. Preoperative Local Administration of Morphine as an Add-on Therapy in Patients Undergoing Surgical Removal of an Odontogenic Maxillary Cyst. A Randomized, Double-Blind Pilot Study. J Oral Facial Pain Headache. 2015;29:378-83 pubmed publisher
Kumar V, Cabana H. Towards high potential magnetic biocatalysts for on-demand elimination of pharmaceuticals. Bioresour Technol. 2016;200:81-9 pubmed publisher
Chen X, Vollertsen J, Nielsen J, Dall A, Bester K. Degradation of PPCPs in activated sludge from different WWTPs in Denmark. Ecotoxicology. 2015;24:2073-80 pubmed publisher
Ribeiro N, Panizza H, Santos K, Ferreira Neto H, Antunes V. Salt-induced sympathoexcitation involves vasopressin V1a receptor activation in the paraventricular nucleus of the hypothalamus. Am J Physiol Regul Integr Comp Physiol. 2015;309:R1369-79 pubmed publisher
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Marini D, Pippia J, Colditz I, Hinch G, Petherick J, Lee C. Randomised trial of the bioavailability and efficacy of orally administered flunixin, carprofen and ketoprofen in a pain model in sheep. Aust Vet J. 2015;93:265-70 pubmed publisher
Chantasart D, Chootanasoontorn S, Suksiriworapong J, Li S. Investigation of pH Influence on Skin Permeation Behavior of Weak Acids Using Nonsteroidal Anti-Inflammatory Drugs. J Pharm Sci. 2015;104:3459-70 pubmed publisher
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Nishi I, Kawakami T, Onodera S. Monitoring the concentrations of nonsteroidal anti-inflammatory drugs and cyclooxygenase-inhibiting activities in the surface waters of the Tone Canal and Edo River Basin. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2015;50:1108-15 pubmed publisher
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Wulff R, Rappen G, Koziolek M, Garbacz G, Leopold C. Controlled release of acidic drugs in compendial and physiological hydrogen carbonate buffer from polymer blend-coated oral solid dosage forms. Eur J Pharm Sci. 2015;77:246-53 pubmed publisher
Cerciello A, Auriemma G, Morello S, Pinto A, Del Gaudio P, Russo P, et al. Design and In Vivo Anti-Inflammatory Effect of Ketoprofen Delayed Delivery Systems. J Pharm Sci. 2015;104:3451-8 pubmed publisher
Nishida H, Hirota M, Seto Y, Suzuki G, Kato M, Kitagaki M, et al. Non-animal photosafety screening for complex cosmetic ingredients with photochemical and photobiochemical assessment tools. Regul Toxicol Pharmacol. 2015;72:578-85 pubmed publisher
Krieg B, Taghavi S, Amidon G, Amidon G. In Vivo Predictive Dissolution: Comparing the Effect of Bicarbonate and Phosphate Buffer on the Dissolution of Weak Acids and Weak Bases. J Pharm Sci. 2015;104:2894-904 pubmed publisher
Manoharan P, Wong Y, Tayyab S. Stabilization of Human Serum Albumin against Urea Denaturation by Diazepam and Ketoprofen. Protein Pept Lett. 2015;22:611-7 pubmed
Nakov N, Petkovska R, Ugrinova L, Kavrakovski Z, Dimitrovska A, Svinarov D. Critical development by design of a rugged HPLC-MS/MS method for direct determination of ibuprofen enantiomers in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;992:67-75 pubmed publisher
Bamji S, Page R, Patel D, Sanders A, Alvarez A, Gambrell C, et al. Soy glyceollins regulate transcript abundance in the female mouse brain. Funct Integr Genomics. 2015;15:549-61 pubmed publisher
Padró J, Osorio Grisales J, Arancibia J, Olivieri A, Castells C. Scope of partial least-squares regression applied to the enantiomeric composition determination of ketoprofen from strongly overlapped chromatographic profiles. J Sep Sci. 2015;38:2423-30 pubmed publisher
Wang Y, Wan P. Ketoprofen as a photoinitiator for anionic polymerization. Photochem Photobiol Sci. 2015;14:1120-6 pubmed publisher
Liu W, Lirio S, Yang Y, Wu L, Hsiao S, Huang H. A poly(alkyl methacrylate-divinylbenzene-vinylbenzyl trimethylammonium chloride) monolithic column for solid-phase microextraction. J Chromatogr A. 2015;1395:32-40 pubmed publisher
Li Y, Yang J, Huang C, Wang L, Wang J, Chen J. Dendrimer-functionalized mesoporous silica as a reversed-phase/anion-exchange mixed-mode sorbent for solid phase extraction of acid drugs in human urine. J Chromatogr A. 2015;1392:28-36 pubmed publisher
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Szkudlarek A, Sułkowska A, Maciążek Jurczyk M, Chudzik M, Równicka Zubik J. Effects of non-enzymatic glycation in human serum albumin. Spectroscopic analysis. Spectrochim Acta A Mol Biomol Spectrosc. 2016;152:645-53 pubmed publisher
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Miller T, McEneff G, Brown R, Owen S, Bury N, Barron L. Pharmaceuticals in the freshwater invertebrate, Gammarus pulex, determined using pulverised liquid extraction, solid phase extraction and liquid chromatography-tandem mass spectrometry. Sci Total Environ. 2015;511:153-60 pubmed publisher
Hidalgo C, Ramos Payán M, Ocaña González J, Martín Valero M, Bello López M. Agar films containing silver nanoparticles as new supports for electromembrane extraction. Anal Bioanal Chem. 2015;407:1519-25 pubmed publisher
Lolić A, Paíga P, Santos L, Ramos S, Correia M, Delerue Matos C. Assessment of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawaters of North of Portugal: occurrence and environmental risk. Sci Total Environ. 2015;508:240-50 pubmed publisher
Diniz M, Salgado R, Pereira V, Carvalho G, Oehmen A, Reis M, et al. Ecotoxicity of ketoprofen, diclofenac, atenolol and their photolysis byproducts in zebrafish (Danio rerio). Sci Total Environ. 2015;505:282-9 pubmed publisher
Han S, Hu L, Quach T, Simpson J, Trevaskis N, Porter C. Profiling the role of deacylation-reacylation in the lymphatic transport of a triglyceride-mimetic prodrug. Pharm Res. 2015;32:1830-44 pubmed publisher
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Durgan D, Crossland R, Lloyd E, Phillips S, Bryan R. Increased cerebrovascular sensitivity to endothelin-1 in a rat model of obstructive sleep apnea: a role for endothelin receptor B. J Cereb Blood Flow Metab. 2015;35:402-11 pubmed publisher
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Maciążek Jurczyk M. Phenylbutazone and ketoprofen binding to serum albumin. Fluorescence study. Pharmacol Rep. 2014;66:727-31 pubmed publisher
Perrenoud A, Farrell W, Aurigemma C, Aurigemma N, Fekete S, Guillarme D. Evaluation of stationary phases packed with superficially porous particles for the analysis of pharmaceutical compounds using supercritical fluid chromatography. J Chromatogr A. 2014;1360:275-87 pubmed publisher
Lee C, Shin Y, Nam M, Jeong K, Lee J. A new analytical method to determine non-steroidal anti-inflammatory drugs in surface water using in situ derivatization combined with ultrasound-assisted emulsification microextraction followed by gas chromatography-mass spectrometry. Talanta. 2014;129:552-9 pubmed publisher
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Kang J, Park S, Park H, Gedi V, So B, Lee K. Multiresidue determination of ten nonsteroidal anti-inflammatory drugs in bovine, porcine, and chicken liver tissues by HPLC-MS/MS. Appl Biochem Biotechnol. 2014;174:1-5 pubmed publisher
Reddy I, Wasserman D, Ayala J, Hasty A, Abumrad N, Galli A. Striatal dopamine homeostasis is altered in mice following Roux-en-Y gastric bypass surgery. ACS Chem Neurosci. 2014;5:943-51 pubmed publisher
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Montesdeoca Esponda S, Mahugo Santana C, Sosa Ferrera Z, Santana Rodríguez J. A dispersive liquid-liquid micellar microextraction for the determination of pharmaceutical compounds in wastewaters using ultra-high-performace liquid chromatography with DAD detection. Biomed Chromatogr. 2015;29:353-6 pubmed publisher
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Paíga P, Lolić A, Hellebuyck F, Santos L, Correia M, Delerue Matos C. Development of a SPE-UHPLC-MS/MS methodology for the determination of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawater. J Pharm Biomed Anal. 2015;106:61-70 pubmed publisher
Dawas Massalha A, Gur Reznik S, Lerman S, Sabbah I, Dosoretz C. Co-metabolic oxidation of pharmaceutical compounds by a nitrifying bacterial enrichment. Bioresour Technol. 2014;167:336-42 pubmed publisher
Albals D, Hendrickx A, Clincke L, Chankvetadze B, Heyden Y, Mangelings D. A chiral separation strategy for acidic drugs in capillary electrochromatography using both chlorinated and nonchlorinated polysaccharide-based selectors. Electrophoresis. 2014;35:2807-18 pubmed publisher
Martin J, Santos J, Aparicio I, Alonso E. Pharmaceutically active compounds in sludge stabilization treatments: anaerobic and aerobic digestion, wastewater stabilization ponds and composting. Sci Total Environ. 2015;503-504:97-104 pubmed publisher
Velásquez G, Santa Cruz L, Espinoza M. Ketoprofen is more effective than diclofenac after oral surgery when used as a preemptive analgesic: a pilot study. J Oral Facial Pain Headache. 2014;28:153-8 pubmed publisher
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Medina J, Padilla A, Hurtado M, Cortés A, Domínguez Ramírez A. In vitro release of ketoprofen suppositories using the USP basket and the flow-through cell dissolution methods. Pak J Pharm Sci. 2014;27:453-8 pubmed
Damulin I. [Treatment of back pain (ketoprofen and other methods)]. Zh Nevrol Psikhiatr Im S S Korsakova. 2014;114:81-6 pubmed
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Yang G, Yen C, Wang C. Monitoring and removal of residual phthalate esters and pharmaceuticals in the drinking water of Kaohsiung City, Taiwan. J Hazard Mater. 2014;277:53-61 pubmed publisher
Tamura H, Mori Y, Kaneko H. Organization of local horizontal functional interactions between neurons in the inferior temporal cortex of macaque monkeys. J Neurophysiol. 2014;111:2589-602 pubmed publisher
Jinno N, Tagashira M, Tsurui K, Yamada S. Contribution of cytochrome P450 and UDT-glucuronosyltransferase to the metabolism of drugs containing carboxylic acid groups: risk assessment of acylglucuronides using human hepatocytes. Xenobiotica. 2014;44:677-86 pubmed publisher
Pistolozzi M, Fortugno C, Franchini C, Corbo F, Muraglia M, Roy M, et al. Species-dependent binding of tocainide analogues to albumin: affinity chromatography and circular dichroism study. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;968:69-78 pubmed publisher
Nikumbh K, Sevankar S, Patil M. Formulation development, in vitro and in vivo evaluation of microemulsion-based gel loaded with ketoprofen. Drug Deliv. 2015;22:509-15 pubmed publisher
Kim J, Bae H, Choi J, Lim J, Kim S, Lee S, et al. Efficacy of gastro-retentive forms of ecabet sodium in the treatment of gastric ulcer in rats. Arch Pharm Res. 2014;37:1053-62 pubmed publisher
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Ozguney I, Kardhiqi A. Properties of bioadhesive ketoprofen liquid suppositories: preparation, determination of gelation temperature, viscosity studies and evaluation of mechanical properties using texture analyzer by 4 × 4 factorial design. Pharm Dev Technol. 2014;19:968-75 pubmed publisher
Ray R, Mujtaba S, Dwivedi A, Yadav N, Verma A, Kushwaha H, et al. Singlet oxygen mediated DNA damage induced phototoxicity by ketoprofen resulting in mitochondrial depolarization and lysosomal destabilization. Toxicology. 2013;314:229-37 pubmed publisher
Ozguney I, Kardhiqi A, Yıldız G, Ertan G. In vitro-in vivo evaluation of in situ gelling and thermosensitive ketoprofen liquid suppositories. Eur J Drug Metab Pharmacokinet. 2014;39:283-91 pubmed publisher
Asirvatham Jeyaraj N, King A, Northcott C, Madan S, Fink G. Cyclooxygenase-1 inhibition attenuates angiotensin II-salt hypertension and neurogenic pressor activity in the rat. Am J Physiol Heart Circ Physiol. 2013;305:H1462-70 pubmed publisher
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Souza J, Meira A, Volpato N, Mayorga P, Gottfried C. Effect of phonophoresis on skin permeation of commercial anti-inflammatory gels: sodium diclofenac and ketoprofen. Ultrasound Med Biol. 2013;39:1623-30 pubmed publisher
Sarzi Puttini P, Atzeni F, Lanata L, Bagnasco M. Efficacy of ketoprofen vs. ibuprofen and diclofenac: a systematic review of the literature and meta-analysis. Clin Exp Rheumatol. 2013;31:731-8 pubmed
Conaghan P, Dickson J, Bolten W, Cevc G, Rother M. A multicentre, randomized, placebo- and active-controlled trial comparing the efficacy and safety of topical ketoprofen in Transfersome gel (IDEA-033) with ketoprofen-free vehicle (TDT 064) and oral celecoxib for knee pain associated with osteoarthri. Rheumatology (Oxford). 2013;52:1303-12 pubmed publisher
Trubetskaia E, Boiko A, Khozova A, Kamchatnov P, Petrov S, Otcheskaia O, et al. [Efficacy of ketoprofen lysine salt (artrosilene) in the treatment of nonspecific vertebrogenic pain syndromes in outpatients]. Zh Nevrol Psikhiatr Im S S Korsakova. 2013;113:53-5 pubmed
Yuan Z, Ye Y, Gao F, Yuan H, Lan M, Lou K, et al. Chitosan-graft-β-cyclodextrin nanoparticles as a carrier for controlled drug release. Int J Pharm. 2013;446:191-8 pubmed publisher
Duan Y, Meng X, Wen Z, Ke R, Chen L. Multi-phase partitioning, ecological risk and fate of acidic pharmaceuticals in a wastewater receiving river: the role of colloids. Sci Total Environ. 2013;447:267-73 pubmed publisher
Tunali Y, Akçil E, Dilmen O, Tutuncu A, Koksal G, Akbas S, et al. Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery. J Neurosurg Anesthesiol. 2013;25:143-7 pubmed publisher
Irisson E, Kerbaul F, Parratte S, Hemon Y, Argenson J, Rosencher N, et al. [Perioperative management based on kinetics of bleeding during total primary arthroplasty]. Ann Fr Anesth Reanim. 2013;32:170-4 pubmed publisher
Newby N, Pearl D, LeBlanc S, Leslie K, von Keyserlingk M, Duffield T. The effect of administering ketoprofen on the physiology and behavior of dairy cows following surgery to correct a left displaced abomasum. J Dairy Sci. 2013;96:1511-20 pubmed publisher
Shientag L, Wheeler S, Garlick D, Maranda L. A therapeutic dose of ketoprofen causes acute gastrointestinal bleeding, erosions, and ulcers in rats. J Am Assoc Lab Anim Sci. 2012;51:832-41 pubmed
Fujii S, Hayashi H, Itoh K, Yamada S, Deguchi Y, Kawazu K. Characterization of the carrier-mediated transport of ketoprofen, a nonsteroidal anti-inflammatory drug, in rabbit corneal epithelium cells. J Pharm Pharmacol. 2013;65:171-80 pubmed publisher
Khan I, Serra C, Anton N, Vandamme T. Continuous-flow encapsulation of ketoprofen in copolymer microbeads via co-axial microfluidic device: influence of operating and material parameters on drug carrier properties. Int J Pharm. 2013;441:809-17 pubmed publisher
Xu J, Zhu L, Xu G, Yu W, Ray A. Determination of competitive adsorption isotherm of enantiomers on preparative chromatographic columns using inverse method. J Chromatogr A. 2013;1273:49-56 pubmed publisher
Barulin A, Kurushina O. [Complex therapy of acute and chronic back pain with dexalgin]. Zh Nevrol Psikhiatr Im S S Korsakova. 2012;112:61-4 pubmed
Majewska M, Kołodziej M, Szponar J, Drelich G, Danielewicz P, Kostek H. [Noncardiogenic pulmonary edema in the course of poisoning with clozapine, ketoprofen and thiethylperazine]. Przegl Lek. 2012;69:618-20 pubmed
Lubelska K, Milczarek M, Modzelewska K, Krzyszton Russjan J, Fronczyk K, Wiktorska K. Interactions between drugs and sulforaphane modulate the drug metabolism enzymatic system. Pharmacol Rep. 2012;64:1243-52 pubmed
Su T, Ma J, Li M, Guan X, Yu L, Phillips D. Time-resolved spectroscopic study of the photochemistry of tiaprofenic acid in a neutral phosphate buffered aqueous solution from femtoseconds to final products. J Phys Chem B. 2013;117:811-24 pubmed publisher
Ozer A, Erhan O, Keles E, Demirel I, Bestas A, Gunduz G. Comparison of the effects of preoperative and intraoperative intravenous application of dexketoprofen on postoperative analgesia in septorhinoplasty patients: randomised double blind clinical trial. Eur Rev Med Pharmacol Sci. 2012;16:1828-33 pubmed
Anneken J, Cunningham J, Collins S, Yamamoto B, Gudelsky G. MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase. J Neuroimmune Pharmacol. 2013;8:58-65 pubmed publisher
Salgado R, Pereira V, Carvalho G, Soeiro R, Gaffney V, Almeida C, et al. Photodegradation kinetics and transformation products of ketoprofen, diclofenac and atenolol in pure water and treated wastewater. J Hazard Mater. 2013;244-245:516-27 pubmed publisher
Conti R, Bassi A, Difonzo E, Moretti S, Francalanci S. A case of photoallergic contact dermatitis caused by unusual exposure to ketoprofen. Dermatitis. 2012;23:295-6 pubmed publisher
Elmorsi Y, El Haggar S, Ibrahim O, Mabrouk M. Effect of ketoprofen and indomethacin on methotrexate pharmacokinetics in mice plasma and tumor tissues. Eur J Drug Metab Pharmacokinet. 2013;38:27-32 pubmed publisher
Gaudio P, Auriemma G, Mencherini T, Porta G, Reverchon E, Aquino R. Design of alginate-based aerogel for nonsteroidal anti-inflammatory drugs controlled delivery systems using prilling and supercritical-assisted drying. J Pharm Sci. 2013;102:185-94 pubmed publisher
Brogliato A, Antunes C, Carvalho R, Monteiro A, Tinoco R, Bozza M, et al. Ketoprofen impairs immunosuppression induced by severe sepsis and reveals an important role for prostaglandin E2. Shock. 2012;38:620-9 pubmed publisher
El Toni A, Khan A, Ibrahim M, Al Hoshan M, Labis J. Fabrication of mesoporous silica shells on solid silica spheres using anionic surfactants and their potential application in controlling drug release. Molecules. 2012;17:13199-210 pubmed publisher
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Mazzocchi A, Montanaro F. Observational study of the use of Symphytum 5CH in the management of pain and swelling after dental implant surgery. Homeopathy. 2012;101:211-6 pubmed publisher
Fischer S, Parmentier J, Buckley S, Reimold I, Brandl M, Fricker G. Oral bioavailability of ketoprofen in suspension and solution formulations in rats: the influence of poloxamer 188. J Pharm Pharmacol. 2012;64:1631-7 pubmed publisher
Lehman P, Raney S. In vitro percutaneous absorption of ketoprofen and testosterone: comparison of pluronic lecithin organogel vs. pentravan cream. Int J Pharm Compd. 2012;16:248-52 pubmed
Macocinschi D, Filip D, Vlad S, Butnaru M, Knieling L. Evaluation of polyurethane based on cellulose derivative-ketoprofen biosystem for implant biomedical devices. Int J Biol Macromol. 2013;52:32-7 pubmed publisher
Degim I, Kadioglu D. Cheap, suitable, predictable and manageable nanoparticles for drug delivery: quantum dots. Curr Drug Deliv. 2013;10:32-8 pubmed
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product information
Catalog Number :
K1751
Product Name :
Ketoprofen
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98% (TLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA