This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Jasplakinolide
catalog :
J4580
citations: 46
Reference
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Shamipour S, Kardos R, Xue S, Hof B, Hannezo E, Heisenberg C. Bulk Actin Dynamics Drive Phase Segregation in Zebrafish Oocytes. Cell. 2019;: pubmed publisher
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Rampérez A, Bartolomé Martín D, Garcia Pascual A, Sánchez Prieto J, Torres M. Photoconversion of FM1-43 Reveals Differences in Synaptic Vesicle Recycling and Sensitivity to Pharmacological Disruption of Actin Dynamics in Individual Synapses. ACS Chem Neurosci. 2019;10:2045-2059 pubmed publisher
Moreno Vicente R, Pavón D, Martin Padura I, Català Montoro M, Díez Sánchez A, Quílez Álvarez A, et al. Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP. Cell Rep. 2018;25:1622-1635.e6 pubmed publisher
Collinson J, Lindström N, Neves C, Wallace K, Meharg C, Charles R, et al. The developmental and genetic basis of 'clubfoot' in the peroneal muscular atrophy mutant mouse. Development. 2018;145: pubmed publisher
Wigerius M, Quinn D, Diab A, Clattenburg L, Kolar A, Qi J, et al. The polarity protein Angiomotin p130 controls dendritic spine maturation. J Cell Biol. 2018;217:715-730 pubmed publisher
Stadler R, White L, Hu K, Helmke B, Guilford W. Direct measurement of cortical force generation and polarization in a living parasite. Mol Biol Cell. 2017;28:1912-1923 pubmed publisher
Gabl M, Winther M, Welin A, Karlsson A, Oprea T, Bylund J, et al. P2Y2 receptor signaling in neutrophils is regulated from inside by a novel cytoskeleton-dependent mechanism. Exp Cell Res. 2015;336:242-52 pubmed publisher
Prod homme V, Boyer L, Dubois N, Mallavialle A, Munro P, Mouska X, et al. Cherubism allele heterozygosity amplifies microbe-induced inflammatory responses in murine macrophages. J Clin Invest. 2015;125:1396-400 pubmed publisher
Trendowski M. Exploiting the cytoskeletal filaments of neoplastic cells to potentiate a novel therapeutic approach. Biochim Biophys Acta. 2014;1846:599-616 pubmed publisher
Choy J, Lu X, Yang J, Zhang Z, Kassab G. Endothelial actin depolymerization mediates NADPH oxidase-superoxide production during flow reversal. Am J Physiol Heart Circ Physiol. 2014;306:H69-77 pubmed publisher
Zouani O, Rami L, Lei Y, Durrieu M. Insights into the osteoblast precursor differentiation towards mature osteoblasts induced by continuous BMP-2 signaling. Biol Open. 2013;2:872-81 pubmed publisher
Dandekar S, Park J, Peng G, Onuffer J, Lim W, Weiner O. Actin dynamics rapidly reset chemoattractant receptor sensitivity following adaptation in neutrophils. Philos Trans R Soc Lond B Biol Sci. 2013;368:20130008 pubmed publisher
Aw Yong K, Zeng Y, Vindivich D, Phillip J, Wu P, Wirtz D, et al. Morphological effects on expression of growth differentiation factor 15 (GDF15), a marker of metastasis. J Cell Physiol. 2014;229:362-73 pubmed publisher
Kojo K, Higaki T, Kutsuna N, Yoshida Y, Yasuhara H, Hasezawa S. Roles of cortical actin microfilament patterning in division plane orientation in plants. Plant Cell Physiol. 2013;54:1491-503 pubmed publisher
Dai Z, Wu F, Chen J, Xu H, Wang H, Guo F, et al. Actin microfilament mediates osteoblast Cbfa1 responsiveness to BMP2 under simulated microgravity. PLoS ONE. 2013;8:e63661 pubmed publisher
Iwase S, Sato R, De Bock P, Gevaert K, Fujiki S, Tawada T, et al. Activation of ADF/cofilin by phosphorylation-regulated Slingshot phosphatase is required for the meiotic spindle assembly in Xenopus laevis oocytes. Mol Biol Cell. 2013;24:1933-46 pubmed publisher
Hellmann J, Perschmann N, Spatz J, Frischknecht F. Tunable substrates unveil chemical complementation of a genetic cell migration defect. Adv Healthc Mater. 2013;2:1162-9 pubmed publisher
Schweikart K, Guo L, Shuler Z, Abrams R, Chiao E, Kolaja K, et al. The effects of jaspamide on human cardiomyocyte function and cardiac ion channel activity. Toxicol In Vitro. 2013;27:745-51 pubmed publisher
Dinic J, Ashrafzadeh P, Parmryd I. Actin filaments attachment at the plasma membrane in live cells cause the formation of ordered lipid domains. Biochim Biophys Acta. 2013;1828:1102-11 pubmed publisher
Mourad N, Nenquin M, Henquin J. Amplification of insulin secretion by acetylcholine or phorbol ester is independent of β-cell microfilaments and distinct from metabolic amplification. Mol Cell Endocrinol. 2013;367:11-20 pubmed publisher
Zhang X, Cui X, Cheng L, Guan X, Li H, Li X, et al. Actin stabilization by jasplakinolide affects the function of bone marrow-derived late endothelial progenitor cells. PLoS ONE. 2012;7:e50899 pubmed publisher
Preira P, Grandné V, Forel J, Gabriele S, Camara M, Theodoly O. Passive circulating cell sorting by deformability using a microfluidic gradual filter. Lab Chip. 2013;13:161-70 pubmed publisher
Noro J, Kalaitzis J, Neilan B. Bioactive natural products from Papua New Guinea marine sponges. Chem Biodivers. 2012;9:2077-95 pubmed publisher
Bartolini F, Ramalingam N, Gundersen G. Actin-capping protein promotes microtubule stability by antagonizing the actin activity of mDia1. Mol Biol Cell. 2012;23:4032-40 pubmed publisher
Whalen K, Reitzel A, Hamdoun A. Actin polymerization controls the activation of multidrug efflux at fertilization by translocation and fine-scale positioning of ABCB1 on microvilli. Mol Biol Cell. 2012;23:3663-72 pubmed publisher
Sörensen P, Iacob R, Fritzsche M, Engen J, Brieher W, Charras G, et al. The natural product cucurbitacin E inhibits depolymerization of actin filaments. ACS Chem Biol. 2012;7:1502-8 pubmed
Amin L, Ercolini E, Shahapure R, Migliorini E, Torre V. The role of membrane stiffness and actin turnover on the force exerted by DRG lamellipodia. Biophys J. 2012;102:2451-60 pubmed publisher
Thaiparambil J, Eggers C, Marcus A. AMPK regulates mitotic spindle orientation through phosphorylation of myosin regulatory light chain. Mol Cell Biol. 2012;32:3203-17 pubmed publisher
Shawl A, Park K, Kim B, Higashida C, Higashida H, Kim U. Involvement of actin filament in the generation of Ca2+ mobilizing messengers in glucose-induced Ca2+ signaling in pancreatic β-cells. Islets. 2012;4:145-51 pubmed publisher
Kavanagh E, Vlachos P, Emourgeon V, Rodhe J, Joseph B. p57(KIP2) control of actin cytoskeleton dynamics is responsible for its mitochondrial pro-apoptotic effect. Cell Death Dis. 2012;3:e311 pubmed publisher
Villanueva J, Torres V, Torregrosa Hetland C, Garcia Martinez V, Lopez Font I, Viniegra S, et al. F-actin-myosin II inhibitors affect chromaffin granule plasma membrane distance and fusion kinetics by retraction of the cytoskeletal cortex. J Mol Neurosci. 2012;48:328-38 pubmed
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Miklavc P, Hecht E, Hobi N, Wittekindt O, Dietl P, Kranz C, et al. Actin coating and compression of fused secretory vesicles are essential for surfactant secretion--a role for Rho, formins and myosin II. J Cell Sci. 2012;125:2765-74 pubmed publisher
Whiteman I, Minamide L, Goh D, Bamburg J, Goldsbury C. Rapid changes in phospho-MAP/tau epitopes during neuronal stress: cofilin-actin rods primarily recruit microtubule binding domain epitopes. PLoS ONE. 2011;6:e20878 pubmed publisher
Wilson C, Tsuchida M, Allen G, Barnhart E, Applegate K, Yam P, et al. Myosin II contributes to cell-scale actin network treadmilling through network disassembly. Nature. 2010;465:373-7 pubmed publisher
Lee C, Han J, Bamburg J, Han L, Lynn R, Zheng J. Regulation of acetylcholine receptor clustering by ADF/cofilin-directed vesicular trafficking. Nat Neurosci. 2009;12:848-56 pubmed publisher
van der Heijden M, Versteilen A, Sipkema P, van Nieuw Amerongen G, Musters R, Groeneveld A. Rho-kinase-dependent F-actin rearrangement is involved in the inhibition of PI3-kinase/Akt during ischemia-reperfusion-induced endothelial cell apoptosis. Apoptosis. 2008;13:404-12 pubmed publisher
Holzinger A. Jasplakinolide. An actin-specific reagent that promotes actin polymerization. Methods Mol Biol. 2001;161:109-20 pubmed
product information
Catalog Number :
J4580
Product Name :
Jasplakinolide
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥97% (HPLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA