This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-Insulin antibody produced in guinea pig
catalog :
I8510
clonality :
polyclonal
host :
guinea-pigs
conjugate :
nonconjugated
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, radioimmunoassay, immunohistochemistry - paraffin section
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; loading ...; fig 2c
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2c
Keller M, Paul P, Rabaglia M, Stapleton D, Schueler K, Broman A, et al. The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets. PLoS Genet. 2016;12:e1006466 pubmed publisher
  • immunohistochemistry; human; 1:500; loading ...; fig s6a
  • immunocytochemistry; mouse; 1:2000; loading ...; fig 1e
  • immunohistochemistry; mouse; 1:500; loading ...; fig 5d
Li J, Casteels T, Frogne T, Ingvorsen C, Honore C, Courtney M, et al. Artemisinins Target GABAA Receptor Signaling and Impair ? Cell Identity. Cell. 2017;168:86-100.e15 pubmed publisher
Pasquier A, Vivot K, Erbs E, Spiegelhalter C, Zhang Z, Aubert V, et al. Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes. Nat Commun. 2019;10:3312 pubmed publisher
Burchfield J, Kebede M, Meoli C, Stöckli J, Whitworth P, Wright A, et al. High dietary fat and sucrose results in an extensive and time-dependent deterioration in health of multiple physiological systems in mice. J Biol Chem. 2018;293:5731-5745 pubmed publisher
Liu K, Leuckx G, Sakano D, Seymour P, Mattsson C, Rautio L, et al. Inhibition of Cdk5 Promotes β-Cell Differentiation From Ductal Progenitors. Diabetes. 2018;67:58-70 pubmed publisher
Paul P, Rabaglia M, Wang C, Stapleton D, Leng N, Kendziorski C, et al. Histone chaperone ASF1B promotes human β-cell proliferation via recruitment of histone H3.3. Cell Cycle. 2016;15:3191-3202 pubmed
Lu J, Liu K, Schulz N, Karampelias C, Charbord J, Hilding A, et al. IGFBP1 increases ?-cell regeneration by promoting ?- to ?-cell transdifferentiation. EMBO J. 2016;35:2026-44 pubmed publisher
Li J, Klughammer J, Farlik M, Penz T, Spittler A, Barbieux C, et al. Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types. EMBO Rep. 2016;17:178-87 pubmed publisher
Denroche H, Quong W, Bruin J, Tudurí E, Asadi A, Glavas M, et al. Leptin administration enhances islet transplant performance in diabetic mice. Diabetes. 2013;62:2738-46 pubmed publisher
product information
cat no :
I8510
brand :
SIGMA
name :
Anti-Insulin antibody produced in guinea pig
prod type :
Chemical
name suffix :
whole antiserum
storage :
-20C
storage temp :
-20C
shipped in :
dry ice
mdl no :
MFCD00162564
unspsc code :
12352203
wgk :
3
antibody form :
whole antiserum
application(s) :
radioimmunoassay: 1:80,000
species reactivity :
pig, human, bovine
immunogen :
pig insulin
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA