This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
3-Iodo-L-tyrosine
catalog :
I8250
citations: 22
Reference
Robles Murguia M, Rao D, Finkelstein D, Xu B, Fan Y, Demontis F. Muscle-derived Dpp regulates feeding initiation via endocrine modulation of brain dopamine biosynthesis. Genes Dev. 2020;34:37-52 pubmed publisher
Monier M, Nöbel S, Danchin E, Isabel G. Dopamine and Serotonin Are Both Required for Mate-Copying in Drosophila melanogaster. Front Behav Neurosci. 2018;12:334 pubmed publisher
Kato Y. An engineered bacterium auxotrophic for an unnatural amino acid: a novel biological containment system. Peerj. 2015;3:e1247 pubmed publisher
Korner G, Noain D, Ying M, Hole M, Flydal M, Scherer T, et al. Brain catecholamine depletion and motor impairment in a Th knock-in mouse with type B tyrosine hydroxylase deficiency. Brain. 2015;138:2948-63 pubmed publisher
Liu S, Wang M, Li X. Overexpression of Tyrosine hydroxylase and Dopa decarboxylase associated with pupal melanization in Spodoptera exigua. Sci Rep. 2015;5:11273 pubmed publisher
Tomita J, Ueno T, Mitsuyoshi M, Kume S, Kume K. The NMDA Receptor Promotes Sleep in the Fruit Fly, Drosophila melanogaster. PLoS ONE. 2015;10:e0128101 pubmed publisher
Ohtake K, Yamaguchi A, Mukai T, Kashimura H, Hirano N, Haruki M, et al. Protein stabilization utilizing a redefined codon. Sci Rep. 2015;5:9762 pubmed publisher
Hornung M, Kosian P, Haselman J, Korte J, Challis K, Macherla C, et al. In Vitro, Ex Vivo, and In Vivo Determination of Thyroid Hormone Modulating Activity of Benzothiazoles. Toxicol Sci. 2015;146:254-64 pubmed publisher
Studer J, Bartsch C, Haas C. Tyrosine hydroxylase TH01 9.3 allele in the occurrence of sudden infant death syndrome in Swiss Caucasians. J Forensic Sci. 2014;59:1650-3 pubmed publisher
Schutte R, Schutte S, Algara J, Barragan E, Gilligan J, Staber C, et al. Knock-in model of Dravet syndrome reveals a constitutive and conditional reduction in sodium current. J Neurophysiol. 2014;112:903-12 pubmed publisher
Hamad M, Engen W, Morris K. Impact of hydration state and molecular oxygen on the chemical stability of levothyroxine sodium. Pharm Dev Technol. 2015;20:314-9 pubmed publisher
Hayashi S, Nakata E, Morita A, Mizuno K, Yamamura K, Kato A, et al. Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pai. Bioorg Med Chem. 2010;18:7675-99 pubmed publisher
Grice C, Tays K, Savall B, Wei J, Butler C, Axe F, et al. Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity. J Med Chem. 2008;51:4150-69 pubmed publisher
Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed
Sakamoto K, Hayashi A, Sakamoto A, Kiga D, Nakayama H, Soma A, et al. Site-specific incorporation of an unnatural amino acid into proteins in mammalian cells. Nucleic Acids Res. 2002;30:4692-9 pubmed
Kucerova Z, Ticha M. Aromatic amino acids and their derivatives as ligands for the isolation of aspartic proteinases. J Chromatogr B Analyt Technol Biomed Life Sci. 2002;770:121-8 pubmed
Harsing L, Zigmond M. Influence of dopamine on GABA release in striatum: evidence for D1-D2 interactions and non-synaptic influences. Neuroscience. 1997;77:419-29 pubmed
Ness D, Foley G, Villar D, Hansen L. Effects of 3-iodo-L-tyrosine, a tyrosine hydroxylase inhibitor, on eye pigmentation and biogenic amines in the planarian, Dugesia dorotocephala. Fundam Appl Toxicol. 1996;30:153-61 pubmed
Muller E, Locatelli V, Cella S, Penalva A, Novelli A, Cocchi D. Prolactin-lowering and -releasing drugs. Mechanisms of action and therapeutic applications. Drugs. 1983;25:399-432 pubmed
Tan S, Lewis J, Berk L, Wilcox R. Extrathyroidal physiology of monoiodotyrosine in humans. Clin Physiol Biochem. 1990;8:109-15 pubmed
Fitzpatrick P. Steady-state kinetic mechanism of rat tyrosine hydroxylase. Biochemistry. 1991;30:3658-62 pubmed
Smythe G, Compton P, Lazarus L. The stimulation of human prolactin secretion by 3-Iodo-L-tyrosine. J Clin Endocrinol Metab. 1975;40:714-6 pubmed
product information
Catalog Number :
I8250
Product Name :
3-Iodo-L-tyrosine
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA