This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Interleukin-4 human
catalog :
I4269
citations: 86
Reference
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Thiemann S, Man J, Chang M, Lee B, Baum L. Galectin-1 regulates tissue exit of specific dendritic cell populations. J Biol Chem. 2015;290:22662-77 pubmed publisher
Ellegård R, Crisci E, Andersson J, Shankar E, Nyström S, Hinkula J, et al. Impaired NK Cell Activation and Chemotaxis toward Dendritic Cells Exposed to Complement-Opsonized HIV-1. J Immunol. 2015;195:1698-704 pubmed publisher
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Shiau M, Lu H, Chang Y, Chiu Y, Shih Y. Characterization of proteins regulated by interleukin-4 in 3T3-L1 adipocytes. Springerplus. 2015;4:242 pubmed publisher
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Ptaschinski C, Mukherjee S, Moore M, Albert M, Helin K, Kunkel S, et al. RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis In Vivo. PLoS Pathog. 2015;11:e1004978 pubmed publisher
Perriard G, Mathias A, Enz L, Canales M, Schluep M, Gentner M, et al. Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes. J Neuroinflammation. 2015;12:119 pubmed publisher
Purwada A, Jaiswal M, Ahn H, Nojima T, Kitamura D, Gaharwar A, et al. Ex vivo engineered immune organoids for controlled germinal center reactions. Biomaterials. 2015;63:24-34 pubmed publisher
Hedbrant A, Wijkander J, Seidal T, Delbro D, Erlandsson A. Macrophages of M1 phenotype have properties that influence lung cancer cell progression. Tumour Biol. 2015;36:8715-25 pubmed publisher
Hoffmann P, Panigada M, Soprana E, Terry F, Bandar I, Napolitano A, et al. Preclinical development of HIvax: Human survivin highly immunogenic vaccines. Hum Vaccin Immunother. 2015;11:1585-95 pubmed publisher
De Falco F, Sabatini R, Del Papa B, Falzetti F, Di Ianni M, Sportoletti P, et al. Notch signaling sustains the expression of Mcl-1 and the activity of eIF4E to promote cell survival in CLL. Oncotarget. 2015;6:16559-72 pubmed
Lee H, Hos D, Blanco T, Bock F, Reyes N, Mathew R, et al. Involvement of corneal lymphangiogenesis in a mouse model of allergic eye disease. Invest Ophthalmol Vis Sci. 2015;56:3140-8 pubmed publisher
Guo M, Yan R, Wang C, Shi H, Sun M, Guo S, et al. IFN Regulatory Factor-1 Modulates the Function of Dendritic Cells in Patients with Acute Coronary Syndrome. Cell Physiol Biochem. 2015;36:599-610 pubmed
Zhang Y, Chen G, Liu Z, Tian S, Zhang J, Carey C, et al. Genetic vaccines to potentiate the effective CD103+ dendritic cell-mediated cross-priming of antitumor immunity. J Immunol. 2015;194:5937-47 pubmed publisher
Wang S, Li Y, Piao H, Hong X, Zhang D, Xu Y, et al. PD-1 and Tim-3 pathways are associated with regulatory CD8+ T-cell function in decidua and maintenance of normal pregnancy. Cell Death Dis. 2015;6:e1738 pubmed publisher
Ayinde D, Bruel T, Cardinaud S, Porrot F, Prado J, Moris A, et al. SAMHD1 Limits HIV-1 Antigen Presentation by Monocyte-Derived Dendritic Cells. J Virol. 2015;89:6994-7006 pubmed
Bouchery T, Kyle R, Camberis M, Shepherd A, Filbey K, Smith A, et al. ILC2s and T cells cooperate to ensure maintenance of M2 macrophages for lung immunity against hookworms. Nat Commun. 2015;6:6970 pubmed publisher
Li C, Liang S, Zhang C, LIU Y, Yang M, Zhang J, et al. Allogenic dendritic cell and tumor cell fused vaccine for targeted imaging and enhanced immunotherapeutic efficacy of gastric cancer. Biomaterials. 2015;54:177-87 pubmed publisher
Jaguin M, Fardel O, Lecureur V. AhR-dependent secretion of PDGF-BB by human classically activated macrophages exposed to DEP extracts stimulates lung fibroblast proliferation. Toxicol Appl Pharmacol. 2015;285:170-8 pubmed publisher
Lathrop S, Binder K, Starr T, Cooper K, Chong A, Carmody A, et al. Replication of Salmonella enterica Serovar Typhimurium in Human Monocyte-Derived Macrophages. Infect Immun. 2015;83:2661-71 pubmed publisher
Dutta D, Potnis P, Rhodes K, Wood S. Wear particles derived from metal hip implants induce the generation of multinucleated giant cells in a 3-dimensional peripheral tissue-equivalent model. PLoS ONE. 2015;10:e0124389 pubmed publisher
Ohkuma K, Matsuda K, Kariya R, Goto H, Kamei S, Hamamoto T, et al. Anti-inflammatory effects of activated protein C on human dendritic cells. Microbiol Immunol. 2015;59:381-8 pubmed publisher
Gardner J, Mamotte C, Patel P, Yeoh T, Jackaman C, Nelson D. Mesothelioma tumor cells modulate dendritic cell lipid content, phenotype and function. PLoS ONE. 2015;10:e0123563 pubmed publisher
Bolisetty S, Zarjou A, Hull T, Traylor A, Perianayagam A, Joseph R, et al. Macrophage and epithelial cell H-ferritin expression regulates renal inflammation. Kidney Int. 2015;88:95-108 pubmed publisher
Liu X, Song N, Liu Y, Liu Y, Li J, Ding J, et al. Efficient induction of anti-tumor immune response in esophageal squamous cell carcinoma via dendritic cells expressing MAGE-A3 and CALR antigens. Cell Immunol. 2015;295:77-82 pubmed publisher
Armitage C, O Meara C, Beagley K. Chlamydia pneumoniae and Chlamydia Trachomatis Infection Differentially Modulates Human Dendritic Cell Line (MUTZ) Differentiation and Activation. Scand J Immunol. 2015;82:48-54 pubmed publisher
Lyrio E, Campos Souza I, Corrêa L, Lechuga G, Verícimo M, Castro H, et al. Interaction of Mycobacterium leprae with the HaCaT human keratinocyte cell line: new frontiers in the cellular immunology of leprosy. Exp Dermatol. 2015;24:536-42 pubmed publisher
Kanayasu Toyoda T, Tanaka T, Ishii Watabe A, Kitagawa H, Matsuyama A, Uchida E, et al. Angiogenic Role of MMP-2/9 Expressed on the Cell Surface of Early Endothelial Progenitor Cells/Myeloid Angiogenic Cells. J Cell Physiol. 2015;230:2763-75 pubmed publisher
Paparini D, Gori S, Grasso E, Scordo W, Calo G, Perez Leiros C, et al. Acetylcholine contributes to control the physiological inflammatory response during the peri-implantation period. Acta Physiol (Oxf). 2015;214:237-47 pubmed publisher
Qin T, Wang C, Chen X, Duan C, Zhang X, Zhang J, et al. Dopamine induces growth inhibition and vascular normalization through reprogramming M2-polarized macrophages in rat C6 glioma. Toxicol Appl Pharmacol. 2015;286:112-23 pubmed publisher
Lu H, Huang D, Yao K, Li C, Chang S, Dai Y, et al. Insulin enhances dendritic cell maturation and scavenger receptor-mediated uptake of oxidised low-density lipoprotein. J Diabetes Complications. 2015;29:465-71 pubmed publisher
Lin S, Wu S, Chou Y, Lin J, Huang Y, Chen M, et al. Novel expression and regulation of TIMP-1 in Epstein Barr virus-infected cells and its impact on cell survival. Virology. 2015;481:24-33 pubmed publisher
Chen Y, Li L, Lu Y, Su Q, Sun Y, Liu Y, et al. Upregulation of miR-155 in CD4(+) T Cells Promoted Th1 Bias in Patients With Unstable Angina. J Cell Physiol. 2015;230:2498-509 pubmed publisher
Zhu H, Jin X, Zhao J, Dong Z, Ma X, Xu F, et al. Probucol Protects Against Atherosclerosis Through Lipid-lowering and Suppressing Immune Maturation of CD11c+ Dendritic Cells in STZ-induced Diabetic LDLR-/- Mice. J Cardiovasc Pharmacol. 2015;65:620-7 pubmed publisher
Liu X, Sun N, Dong Y, Li J, Liu Y, Ren Y, et al. Anticancer effects of adenovirus-mediated calreticulin and melanoma-associated antigen 3 expression on non-small cell lung cancer cells. Int Immunopharmacol. 2015;25:416-24 pubmed publisher
Liu X, Fan B, Bai J, Wang H, Li Y, Jiang P. The N-N non-covalent domain of the nucleocapsid protein of type 2 porcine reproductive and respiratory syndrome virus enhances induction of IL-10 expression. J Gen Virol. 2015;96:1276-86 pubmed publisher
Panek C, Ramos M, Mejías M, Abrey Recalde M, Fernandez Brando R, Gori M, et al. Differential expression of the fractalkine chemokine receptor (CX3CR1) in human monocytes during differentiation. Cell Mol Immunol. 2015;12:669-80 pubmed publisher
Zeissig S, Petersen B, Tomczak M, Melum E, Huc Claustre E, Dougan S, et al. Early-onset Crohn's disease and autoimmunity associated with a variant in CTLA-4. Gut. 2015;64:1889-97 pubmed publisher
Salánki R, Hos C, Orgovan N, Peter B, Sándor N, Bajtay Z, et al. Single cell adhesion assay using computer controlled micropipette. PLoS ONE. 2014;9:e111450 pubmed publisher
Rizzo M, Bayo J, Piccioni F, Malvicini M, Fiore E, Peixoto E, et al. Low molecular weight hyaluronan-pulsed human dendritic cells showed increased migration capacity and induced resistance to tumor chemoattraction. PLoS ONE. 2014;9:e107944 pubmed publisher
Platzer B, Baker K, Vera M, Singer K, Panduro M, Lexmond W, et al. Dendritic cell-bound IgE functions to restrain allergic inflammation at mucosal sites. Mucosal Immunol. 2015;8:516-32 pubmed publisher
Normanton M, Alvarenga H, Hamerschlak N, Ribeiro A, Kondo A, Rizzo L, et al. Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion. PLoS ONE. 2014;9:e106673 pubmed publisher
Wang S, Wang Y, Liu J, Shao S, Li X, Gao J, et al. Silencing B7-H1 enhances the anti-tumor effect of bladder cancer antigen-loaded dendritic cell vaccine in vitro. Onco Targets Ther. 2014;7:1389-96 pubmed publisher
Wang L, Zhang L, Feng X, Xing L, Zhang W, Jiang K, et al. The Functional Difference of Dendritic Cells in HBeAg Negative Chronic Hepatitis B Patients with Three Different Spleen Deficiency Syndromes and the Therapeutic Evaluation of Chinese Medicine Intervention Based on Syndrome Differentiation. Evid Based Complement Alternat Med. 2014;2014:802402 pubmed publisher
Hynönen U, Kant R, Lähteinen T, Pietila T, Beganović J, Smidt H, et al. Functional characterization of probiotic surface layer protein-carrying Lactobacillus amylovorus strains. BMC Microbiol. 2014;14:199 pubmed publisher
Rivellese F, Suurmond J, de Paulis A, Marone G, Huizinga T, Toes R. IgE and IL-33-mediated triggering of human basophils inhibits TLR4-induced monocyte activation. Eur J Immunol. 2014;44:3045-55 pubmed publisher
Kweon H, Kim S, Choi J. Inhibition of foreign body giant cell formation by 4- hexylresorcinol through suppression of diacylglycerol kinase delta gene expression. Biomaterials. 2014;35:8576-84 pubmed publisher
Williams M, Mayer S, Johnson W, Chen R, Volkova E, Vilcarromero S, et al. Lineage II of Southeast Asian/American DENV-2 is associated with a severe dengue outbreak in the Peruvian Amazon. Am J Trop Med Hyg. 2014;91:611-20 pubmed publisher
Wei R, Dong L, Xiao Q, Sun D, Li X, Nian H. Engagement of Toll-like receptor 2 enhances interleukin (IL)-17(+) autoreactive T cell responses via p38 mitogen-activated protein kinase signalling in dendritic cells. Clin Exp Immunol. 2014;178:353-63 pubmed publisher
Tanaka A, Zhu Q, Tan H, Horiba H, Ohnuki K, Mori Y, et al. Biological activities and phytochemical profiles of extracts from different parts of bamboo (Phyllostachys pubescens). Molecules. 2014;19:8238-60 pubmed publisher
Hernandez C, Barrachina M, Cosin Roger J, Ortiz Masia D, Alvarez A, Terrádez L, et al. Progastrin represses the alternative activation of human macrophages and modulates their influence on colon cancer epithelial cells. PLoS ONE. 2014;9:e98458 pubmed publisher
Winkelmann R, Sandrock L, Kirberg J, Jack H, Schuh W. KLF2--a negative regulator of pre-B cell clonal expansion and B cell activation. PLoS ONE. 2014;9:e97953 pubmed publisher
Horiuchi K, Imai K, Mitsui Sekinaka K, Yeh T, Ochs H, Durandy A, et al. Analysis of somatic hypermutations in the IgM switch region in human B cells. J Allergy Clin Immunol. 2014;134:411-9 pubmed publisher
Valente M, Baey C, Louche P, Dutertre C, Vimeux L, Marañon C, et al. Apoptotic cell capture by DCs induces unexpectedly robust autologous CD4+ T-cell responses. Eur J Immunol. 2014;44:2274-86 pubmed publisher
Wang X, Zhang F, Zhao H, Lu X, Sun Y, Xiong Z, et al. Human IP10-scFv and DC-induced CTL synergistically inhibit the growth of glioma in a xenograft model. Tumour Biol. 2014;35:7781-91 pubmed publisher
Smith I, Christensen J, Arneborg N, Jespersen L. Yeast modulation of human dendritic cell cytokine secretion: an in vitro study. PLoS ONE. 2014;9:e96595 pubmed publisher
Favila M, Geraci N, Zeng E, Harker B, Condon D, Cotton R, et al. Human dendritic cells exhibit a pronounced type I IFN signature following Leishmania major infection that is required for IL-12 induction. J Immunol. 2014;192:5863-72 pubmed publisher
Dong W, Zhang J, Shao N, Tian T, Li L, Jian J, et al. Development and immunological evaluation of HLA-specific chronic myeloid leukemia polyepitope vaccine in Chinese population. Vaccine. 2014;32:3501-8 pubmed publisher
Rappocciolo G, Jais M, Piazza P, Reinhart T, Berendam S, García Expósito L, et al. Alterations in cholesterol metabolism restrict HIV-1 trans infection in nonprogressors. MBio. 2014;5:e01031-13 pubmed publisher
Kobayashi M, Shimodaira S, Nagai K, Ogasawara M, Takahashi H, Abe H, et al. Prognostic factors related to add-on dendritic cell vaccines on patients with inoperable pancreatic cancer receiving chemotherapy: a multicenter analysis. Cancer Immunol Immunother. 2014;63:797-806 pubmed publisher
Gaffal E, Glodde N, Jakobs M, Bald T, Tüting T. Cannabinoid 1 receptors in keratinocytes attenuate fluorescein isothiocyanate-induced mouse atopic-like dermatitis. Exp Dermatol. 2014;23:401-6 pubmed publisher
Ciszewski W, Wagner W, Kania K, Dastych J. Interleukin-4 enhances PARP-dependent DNA repair activity in vitro. J Interferon Cytokine Res. 2014;34:734-40 pubmed publisher
Rydnert F, Lundberg K, Greiff L, Lindstedt M. Circulating CD1c(+) DCs are superior at activating Th2 responses upon Phl p stimulation compared with basophils and pDCs. Immunol Cell Biol. 2014;92:557-60 pubmed publisher
Saleh R, Wedeh G, Herrmann H, Bibi S, Cerny Reiterer S, Sadovnik I, et al. A new human mast cell line expressing a functional IgE receptor converts to tumorigenic growth by KIT D816V transfection. Blood. 2014;124:111-20 pubmed publisher
Rebhandl S, Huemer M, Zaborsky N, Gassner F, Catakovic K, Felder T, et al. Alternative splice variants of AID are not stoichiometrically present at the protein level in chronic lymphocytic leukemia. Eur J Immunol. 2014;44:2175-87 pubmed publisher
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Stenger R, Meiring H, Kuipers B, Poelen M, van Gaans van den Brink J, Boog C, et al. Bordetella pertussis proteins dominating the major histocompatibility complex class II-presented epitope repertoire in human monocyte-derived dendritic cells. Clin Vaccine Immunol. 2014;21:641-50 pubmed publisher
Marique L, Van Regemorter V, Gérard A, Craps J, Senou M, Marbaix E, et al. The expression of dual oxidase, thyroid peroxidase, and caveolin-1 differs according to the type of immune response (TH1/TH2) involved in thyroid autoimmune disorders. J Clin Endocrinol Metab. 2014;99:1722-32 pubmed publisher
Cho D, Kim M, Jeong H, Jeong H, Jeong M, Yoon S, et al. Mesenchymal stem cells reciprocally regulate the M1/M2 balance in mouse bone marrow-derived macrophages. Exp Mol Med. 2014;46:e70 pubmed publisher
Futterleib J, Feng H, Tigelaar R, Choi J, Edelson R. Activation of GILZ gene by photoactivated 8-methoxypsoralen: potential role of immunoregulatory dendritic cells in extracorporeal photochemotherapy. Transfus Apher Sci. 2014;50:379-87 pubmed publisher
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Lee I, Kim J, Ko E, Jeoung E, Kwon Y, Choe J. Interleukin-4 inhibits the vascular endothelial growth factor- and basic fibroblast growth factor-induced angiogenesis in vitro. Mol Cells. 2002;14:115-21 pubmed
Yokota T, Otsuka T, Mosmann T, Banchereau J, Defrance T, Blanchard D, et al. Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities. Proc Natl Acad Sci U S A. 1986;83:5894-8 pubmed
product information
Catalog Number :
I4269
Product Name :
Interleukin-4 human
Product Type :
GROWTH FACTORS
Product Group :
Cell Biology
Product Description :
IL-4, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA