Ahn S, Jang D, Park S, An S, Shin J, Han B, et al. Cyclin-Dependent Kinase 5 Inhibitor Butyrolactone I Elicits a Partial Agonist Activity of Peroxisome Proliferator-Activated Receptor γ. Biomolecules. 2020;10: pubmed publisher

Zhao L, Zhou Y, Zhao Y, Li Q, Zhou J, Mao Y. Long non-coding RNA TUSC8 inhibits breast cancer growth and metastasis via miR-190b-5p/MYLIP axis. Aging (Albany NY). 2020;12:2974-2991 pubmed publisher

Chen L, Marsiglia W, Chen H, Katigbak J, Erdjument Bromage H, Kemble D, et al. Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation. Nat Chem Biol. 2020;16:267-277 pubmed publisher

Helsley R, Varadharajan V, Brown A, Gromovsky A, Schugar R, Ramachandiran I, et al. Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease. elife. 2019;8: pubmed publisher

Schalkwijk J, Allman E, Jansen P, de Vries L, Verhoef J, Jackowski S, et al. Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum. Sci Transl Med. 2019;11: pubmed publisher

Martinov T, Swanson L, Breed E, Tucker C, Dwyer A, Johnson J, et al. Programmed Death-1 Restrains the Germinal Center in Type 1 Diabetes. J Immunol. 2019;203:844-852 pubmed publisher

Li Q, Dixon G, Verma N, Rosen B, Gordillo M, Luo R, et al. Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation. Nat Genet. 2019;: pubmed publisher

Stedden C, Menegas W, Zajac A, Williams A, Cheng S, Ozkan E, et al. Planar-Polarized Semaphorin-5c and Plexin A Promote the Collective Migration of Epithelial Cells in Drosophila. Curr Biol. 2019;: pubmed publisher

Sposato V, Canu N, Fico E, Fusco S, Bolasco G, Ciotti M, et al. The Medial Septum Is Insulin Resistant in the AD Presymptomatic Phase: Rescue by Nerve Growth Factor-Driven IRS1 Activation. Mol Neurobiol. 2019;56:535-552 pubmed publisher

Silva A, Sárkány Z, Fraga J, Taboada P, Macedo Ribeiro S, Martins P. Probing the Occurrence of Soluble Oligomers through Amyloid Aggregation Scaling Laws. Biomolecules. 2018;8: pubmed publisher

Akhshabi S, Biazar E, Singh V, Keshel S, Geetha N. The effect of the carbodiimide cross-linker on the structural and biocompatibility properties of collagen-chondroitin sulfate electrospun mat. Int J Nanomedicine. 2018;13:4405-4416 pubmed publisher

Boteon Y, Wallace L, Boteon A, Mirza D, Mergental H, Bhogal R, et al. An effective protocol for pharmacological defatting of primary human hepatocytes which is non-toxic to cholangiocytes or intrahepatic endothelial cells. PLoS ONE. 2018;13:e0201419 pubmed publisher

Musselman L, Fink J, Maier E, Gatto J, Brent M, Baranski T. Seven-Up Is a Novel Regulator of Insulin Signaling. Genetics. 2018;208:1643-1656 pubmed publisher

Gutmann T, Kim K, Grzybek M, Walz T, Coskun U. Visualization of ligand-induced transmembrane signaling in the full-length human insulin receptor. J Cell Biol. 2018;217:1643-1649 pubmed publisher

Chen J, Nagle A, Wang Y, Boone D, Lee A. Controlled dimerization of insulin-like growth factor-1 and insulin receptors reveals shared and distinct activities of holo and hybrid receptors. J Biol Chem. 2018;293:3700-3709 pubmed publisher

Musselman L, Fink J, Grant A, Gatto J, Tuthill B, Baranski T. A Complex Relationship between Immunity and Metabolism in Drosophila Diet-Induced Insulin Resistance. Mol Cell Biol. 2018;38: pubmed publisher

Viviano A, Yin X, Zampetaki A, Fava M, Gallagher M, Mayr M, et al. Proteomics of the epicardial fat secretome and its role in post-operative atrial fibrillation. Europace. 2018;20:1201-1208 pubmed publisher

Budel L, Djabali K. Rapid isolation and expansion of skin-derived precursor cells from human primary fibroblast cultures. Biol Open. 2017;6:1745-1755 pubmed publisher

Shen H, Campanello G, Flicker D, Grabarek Z, Hu J, Luo C, et al. The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B12. Cell. 2017;171:771-782.e11 pubmed publisher

Oliver S, Brooke B. The effects of ingestion of hormonal host factors on the longevity and insecticide resistance phenotype of the major malaria vector Anopheles arabiensis (Diptera: Culicidae). PLoS ONE. 2017;12:e0180909 pubmed publisher

Gupta R, Ma Y, Wang M, Whim M. AgRP-Expressing Adrenal Chromaffin Cells Are Involved in the Sympathetic Response to Fasting. Endocrinology. 2017;158:2572-2584 pubmed publisher

Esteban Martínez L, Sierra Filardi E, McGreal R, Salazar Roa M, Mariño G, Seco E, et al. Programmed mitophagy is essential for the glycolytic switch during cell differentiation. EMBO J. 2017;36:1688-1706 pubmed publisher

García Sanz P, Mirasierra M, Moratalla R, Vallejo M. Embryonic defence mechanisms against glucose-dependent oxidative stress require enhanced expression of Alx3 to prevent malformations during diabetic pregnancy. Sci Rep. 2017;7:389 pubmed publisher

Alzebdeh D, Matthew H. Metabolic Oscillations in Co-Cultures of Hepatocytes and Mesenchymal Stem Cells: Effects of Seeding Arrangement and Culture Mixing. J Cell Biochem. 2017;118:3003-3015 pubmed publisher

Ebner M, Sinkovics B, Szczygieł M, Ribeiro D, Yudushkin I. Localization of mTORC2 activity inside cells. J Cell Biol. 2017;216:343-353 pubmed publisher

Lancina M, Shankar R, Yang H. Chitosan nanofibers for transbuccal insulin delivery. J Biomed Mater Res A. 2017;105:1252-1259 pubmed publisher

Meerson A, Yehuda H. Leptin and insulin up-regulate miR-4443 to suppress NCOA1 and TRAF4, and decrease the invasiveness of human colon cancer cells. BMC Cancer. 2016;16:882 pubmed

Lin M, Sambo D, Khoshbouei H. Methamphetamine Regulation of Firing Activity of Dopamine Neurons. J Neurosci. 2016;36:10376-10391 pubmed

Varinli H, Osmond McLeod M, Molloy P, Vallotton P. LipiD-QuanT: a novel method to quantify lipid accumulation in live cells. J Lipid Res. 2015;56:2206-16 pubmed publisher

Kohyama Koganeya A, Kurosawa M, Hirabayashi Y. Differential Effects of Tissue-Specific Deletion of BOSS on Feeding Behaviors and Energy Metabolism. PLoS ONE. 2015;10:e0133083 pubmed publisher

Adzovic L, Lynn A, D Angelo H, Crockett A, Kaercher R, Royer S, et al. Insulin improves memory and reduces chronic neuroinflammation in the hippocampus of young but not aged brains. J Neuroinflammation. 2015;12:63 pubmed publisher

Kobayashi A, Okuda H, Xing F, Pandey P, Watabe M, Hirota S, et al. Bone morphogenetic protein 7 in dormancy and metastasis of prostate cancer stem-like cells in bone. J Exp Med. 2011;208:2641-55 pubmed publisher

Dayal S, Nedbal J, Hobson P, Cooper A, Gould H, Gellert M, et al. High resolution analysis of the chromatin landscape of the IgE switch region in human B cells. PLoS ONE. 2011;6:e24571 pubmed publisher

Li H, Baldwin B, Zahnow C. LIP expression is regulated by IGF-1R signaling and participates in suppression of anoikis. Mol Cancer. 2011;10:100 pubmed publisher

Kwon Y, Cukierman E, Godwin A. Differential expressions of adhesive molecules and proteases define mechanisms of ovarian tumor cell matrix penetration/invasion. PLoS ONE. 2011;6:e18872 pubmed publisher

Salvagiotto G, Burton S, Daigh C, Rajesh D, Slukvin I, Seay N. A defined, feeder-free, serum-free system to generate in vitro hematopoietic progenitors and differentiated blood cells from hESCs and hiPSCs. PLoS ONE. 2011;6:e17829 pubmed publisher

Lira F, Rosa J, Cunha C, Ribeiro E, do Nascimento C, Oyama L, et al. Supplementing alpha-tocopherol (vitamin E) and vitamin D3 in high fat diet decrease IL-6 production in murine epididymal adipose tissue and 3T3-L1 adipocytes following LPS stimulation. Lipids Health Dis. 2011;10:37 pubmed publisher

Verstraeten V, Renes J, Ramaekers F, Kamps M, Kuijpers H, Verheyen F, et al. Reorganization of the nuclear lamina and cytoskeleton in adipogenesis. Histochem Cell Biol. 2011;135:251-61 pubmed publisher

Cinova J, De Palma G, Stepankova R, Kofronova O, Kverka M, Sanz Y, et al. Role of intestinal bacteria in gliadin-induced changes in intestinal mucosa: study in germ-free rats. PLoS ONE. 2011;6:e16169 pubmed publisher

Corpet A, de Koning L, Toedling J, Savignoni A, Berger F, Lemaître C, et al. Asf1b, the necessary Asf1 isoform for proliferation, is predictive of outcome in breast cancer. EMBO J. 2011;30:480-93 pubmed publisher

Jung H, Kim Y, Lee J. Duration and magnitude of extracellular signal-regulated protein kinase phosphorylation determine adipogenesis or osteogenesis in human bone marrow-derived stem cells. Yonsei Med J. 2011;52:165-72 pubmed publisher

Hommelberg P, Plat J, Sparks L, Schols A, van Essen A, Kelders M, et al. Palmitate-induced skeletal muscle insulin resistance does not require NF-?B activation. Cell Mol Life Sci. 2011;68:1215-25 pubmed publisher

Zimmerlin L, Donnenberg A, Rubin J, Basse P, Landreneau R, Donnenberg V. Regenerative therapy and cancer: in vitro and in vivo studies of the interaction between adipose-derived stem cells and breast cancer cells from clinical isolates. Tissue Eng Part A. 2011;17:93-106 pubmed publisher

Hyun E, Ramachandran R, Cenac N, Houle S, Rousset P, Saxena A, et al. Insulin modulates protease-activated receptor 2 signaling: implications for the innate immune response. J Immunol. 2010;184:2702-9 pubmed publisher

de Koning L, Savignoni A, Boumendil C, Rehman H, Asselain B, Sastre Garau X, et al. Heterochromatin protein 1alpha: a hallmark of cell proliferation relevant to clinical oncology. EMBO Mol Med. 2009;1:178-91 pubmed publisher

Evers B, Schut E, van der Burg E, Braumuller T, Egan D, Holstege H, et al. A high-throughput pharmaceutical screen identifies compounds with specific toxicity against BRCA2-deficient tumors. Clin Cancer Res. 2010;16:99-108 pubmed publisher

Wu M, Yang X, Chan C. A dynamic analysis of IRS-PKR signaling in liver cells: a discrete modeling approach. PLoS ONE. 2009;4:e8040 pubmed publisher

Iliopoulos D, Polytarchou C, Hatziapostolou M, Kottakis F, Maroulakou I, Struhl K, et al. MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells. Sci Signal. 2009;2:ra62 pubmed publisher

Yang L, RAZZAGHI H, Hokanson J, Kamboh M. Identification and characterization of a novel 5 bp deletion in a putative insulin response element in the lipoprotein lipase gene. Biochim Biophys Acta. 2009;1791:1057-65 pubmed publisher

Chen Z, Leibiger I, Katz A, Bertorello A. Pals-associated tight junction protein functionally links dopamine and angiotensin II to the regulation of sodium transport in renal epithelial cells. Br J Pharmacol. 2009;158:486-93 pubmed publisher

Wiltzius J, Sievers S, Sawaya M, Eisenberg D. Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process. Protein Sci. 2009;18:1521-30 pubmed publisher

Fournier M, Fata J, Martin K, Yaswen P, Bissell M. Interaction of E-cadherin and PTEN regulates morphogenesis and growth arrest in human mammary epithelial cells. Cancer Res. 2009;69:4545-52 pubmed publisher

Henry R, Acevedo Suárez C, Thomas J. Functional silencing is initiated and maintained in immature anti-insulin B cells. J Immunol. 2009;182:3432-9 pubmed publisher

Hammond G, Sim Y, Lagnado L, Irvine R. Reversible binding and rapid diffusion of proteins in complex with inositol lipids serves to coordinate free movement with spatial information. J Cell Biol. 2009;184:297-308 pubmed publisher

Dubrovska A, Kim S, Salamone R, Walker J, Maira S, Garcia Echeverria C, et al. The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations. Proc Natl Acad Sci U S A. 2009;106:268-73 pubmed publisher

Haram P, Kemi O, Lee S, Bendheim M, Al Share Q, Waldum H, et al. Aerobic interval training vs. continuous moderate exercise in the metabolic syndrome of rats artificially selected for low aerobic capacity. Cardiovasc Res. 2009;81:723-32 pubmed publisher

Gutierrez G, Kong E, Sabbagh Y, Brown N, Lee J, Demay M, et al. Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice. Proc Natl Acad Sci U S A. 2008;105:18402-7 pubmed publisher

Aoto J, Nam C, Poon M, Ting P, Chen L. Synaptic signaling by all-trans retinoic acid in homeostatic synaptic plasticity. Neuron. 2008;60:308-20 pubmed publisher

Pais T, Figueiredo C, Peixoto R, Braz M, Chatterjee S. Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway. J Neuroinflammation. 2008;5:43 pubmed publisher

Chowdhury M, Forouhi O, Dayal S, McCloskey N, Gould H, Felsenfeld G, et al. Analysis of intergenic transcription and histone modification across the human immunoglobulin heavy-chain locus. Proc Natl Acad Sci U S A. 2008;105:15872-7 pubmed publisher

Beazley K, Nurminskaya M, Talbot C, Linsenmayer T. Corneal epithelial nuclear ferritin: developmental regulation of ferritin and its nuclear transporter ferritoid. Dev Dyn. 2008;237:2529-41 pubmed publisher

Uffort D, Grimm E, Ellerhorst J. NF-kappaB mediates mitogen-activated protein kinase pathway-dependent iNOS expression in human melanoma. J Invest Dermatol. 2009;129:148-54 pubmed publisher

Shao L, Shi H, Ayala G, Rowley D, Zhang M. Haploinsufficiency of the maspin tumor suppressor gene leads to hyperplastic lesions in prostate. Cancer Res. 2008;68:5143-51 pubmed publisher

Green M, Spate L, Parks T, Kimura K, Murphy C, Williams J, et al. Nutritional skewing of conceptus sex in sheep: effects of a maternal diet enriched in rumen-protected polyunsaturated fatty acids (PUFA). Reprod Biol Endocrinol. 2008;6:21 pubmed publisher

Johns D, Wong M, Athanasiou K. Clinically relevant cell sources for TMJ disc engineering. J Dent Res. 2008;87:548-52 pubmed

Sivabalan S, Renuka S, Menon V. Fat feeding potentiates the diabetogenic effect of dexamethasone in Wistar rats. Int Arch Med. 2008;1:7 pubmed publisher

Na S, Collin O, Chowdhury F, Tay B, Ouyang M, Wang Y, et al. Rapid signal transduction in living cells is a unique feature of mechanotransduction. Proc Natl Acad Sci U S A. 2008;105:6626-31 pubmed publisher

Ng E, Davis R, Stanley E, Elefanty A. A protocol describing the use of a recombinant protein-based, animal product-free medium (APEL) for human embryonic stem cell differentiation as spin embryoid bodies. Nat Protoc. 2008;3:768-76 pubmed publisher

Wang K, Chen S, Xie W, Wan Y. Retinoids induce cytochrome P450 3A4 through RXR/VDR-mediated pathway. Biochem Pharmacol. 2008;75:2204-13 pubmed publisher