| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; loading ...; fig 3c
| Cao X, Shu Y, Chen Y, Xu Q, Guo G, Wu Z, et al. Mettl14-Mediated m6A Modification Facilitates Liver Regeneration by Maintaining Endoplasmic Reticulum Homeostasis. Cell Mol Gastroenterol Hepatol. 2021;12:633-651 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 7e
- western blot; human; loading ...; fig 5a
- western blot; mouse; loading ...; fig 1g
| Lü Z, Liu H, Song N, Liang Y, Zhu J, Chen J, et al. METTL14 aggravates podocyte injury and glomerulopathy progression through N6-methyladenosine-dependent downregulating of Sirt1. Cell Death Dis. 2021;12:881 pubmed publisher |
- immunohistochemistry; mouse; fig 2d
- western blot; mouse; loading ...; fig 2b
| Teng Y, Liu Z, Chen X, Liu Y, Geng F, Le W, et al. Conditional deficiency of m6A methyltransferase Mettl14 in substantia nigra alters dopaminergic neuron function. J Cell Mol Med. 2021;25:8567-8572 pubmed publisher |
- immunocytochemistry; mouse; 1:1000; loading ...; fig s2d
| Yu J, Chen M, Huang H, Zhu J, Song H, Zhu J, et al. Dynamic m6A modification regulates local translation of mRNA in axons. Nucleic Acids Res. 2018;46:1412-1423 pubmed publisher |
- western blot; human; loading ...; fig 2c
| Lin S, Choe J, Du P, Triboulet R, Gregory R. The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells. Mol Cell. 2016;62:335-345 pubmed publisher |
| Wang A, Tao W, Tong J, Gao J, Wang J, Hou G, et al. m6A modifications regulate intestinal immunity and rotavirus infection. elife. 2022;11: pubmed publisher |
| Chen S, Kumar S, Espada C, Tirumuru N, Cahill M, Hu L, et al. N6-methyladenosine modification of HIV-1 RNA suppresses type-I interferon induction in differentiated monocytic cells and primary macrophages. PLoS Pathog. 2021;17:e1009421 pubmed publisher |
| Kim G, Siddiqui A. N6-methyladenosine modification of HCV RNA genome regulates cap-independent IRES-mediated translation via YTHDC2 recognition. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher |
| He J, Li Z, Rong Z, Gao J, Mu Y, Guan Y, et al. m6A Reader YTHDC2 Promotes Radiotherapy Resistance of Nasopharyngeal Carcinoma via Activating IGF1R/AKT/S6 Signaling Axis. Front Oncol. 2020;10:1166 pubmed publisher |
| Xu H, Dzhashiashvili Y, Shah A, Kunjamma R, Weng Y, Elbaz B, et al. m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination. Neuron. 2020;105:293-309.e5 pubmed publisher |
| Mao Y, Dong L, Liu X, Guo J, Ma H, Shen B, et al. m6A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2. Nat Commun. 2019;10:5332 pubmed publisher |
| Liu J, Luo G, Sun J, Men L, Ye H, He C, et al. METTL14 is essential for β-cell survival and insulin secretion. Biochim Biophys Acta Mol Basis Dis. 2019;: pubmed publisher |
| Wang H, Hu X, Huang M, Liu J, Gu Y, Ma L, et al. Mettl3-mediated mRNA m6A methylation promotes dendritic cell activation. Nat Commun. 2019;10:1898 pubmed publisher |
| Park O, Ha H, Lee Y, Boo S, Kwon D, Song H, et al. Endoribonucleolytic Cleavage of m6A-Containing RNAs by RNase P/MRP Complex. Mol Cell. 2019;74:494-507.e8 pubmed publisher |
| Selberg S, Blokhina D, Aatonen M, Koivisto P, Siltanen A, Mervaala E, et al. Discovery of Small Molecules that Activate RNA Methylation through Cooperative Binding to the METTL3-14-WTAP Complex Active Site. Cell Rep. 2019;26:3762-3771.e5 pubmed publisher |
| Song H, Feng X, Zhang H, Luo Y, Huang J, Lin M, et al. METTL3 and ALKBH5 oppositely regulate m6A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes. Autophagy. 2019;: pubmed publisher |
| Yang Y, Shen F, Huang W, Qin S, Huang J, Sergi C, et al. Glucose Is Involved in the Dynamic Regulation of m6A in Patients With Type 2 Diabetes. J Clin Endocrinol Metab. 2019;104:665-673 pubmed publisher |
| Panneerdoss S, Eedunuri V, Yadav P, Timilsina S, Rajamanickam S, Viswanadhapalli S, et al. Cross-talk among writers, readers, and erasers of m6A regulates cancer growth and progression. Sci Adv. 2018;4:eaar8263 pubmed publisher |
| Lesbirel S, Viphakone N, Parker M, Parker J, Heath C, Sudbery I, et al. The m6A-methylase complex recruits TREX and regulates mRNA export. Sci Rep. 2018;8:13827 pubmed publisher |
| Liu J, Eckert M, Harada B, Liu S, Lu Z, Yu K, et al. m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018;20:1074-1083 pubmed publisher |
| Koranda J, Dore L, Shi H, Patel M, Vaasjo L, Rao M, et al. Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning. Neuron. 2018;99:283-292.e5 pubmed publisher |
| Sorci M, Ianniello Z, Cruciani S, Larivera S, Ginistrelli L, Capuano E, et al. METTL3 regulates WTAP protein homeostasis. Cell Death Dis. 2018;9:796 pubmed publisher |
| Zhou J, Wan J, Shu X, Mao Y, Liu X, Yuan X, et al. N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response. Mol Cell. 2018;69:636-647.e7 pubmed publisher |
| Wang Y, Li Y, Yue M, Wang J, Kumar S, Wechsler Reya R, et al. N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications. Nat Neurosci. 2018;21:195-206 pubmed publisher |
| Weng H, Huang H, Wu H, Qin X, Zhao B, Dong L, et al. METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification. Cell Stem Cell. 2018;22:191-205.e9 pubmed publisher |
| Tan B, Liu H, Zhang S, da Silva S, Zhang L, Meng J, et al. Viral and cellular N6-methyladenosine and N6,2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018;3:108-120 pubmed publisher |
| Coots R, Liu X, Mao Y, Dong L, Zhou J, Wan J, et al. m6A Facilitates eIF4F-Independent mRNA Translation. Mol Cell. 2017;68:504-514.e7 pubmed publisher |
| Herzog V, Reichholf B, Neumann T, Rescheneder P, Bhat P, Burkard T, et al. Thiol-linked alkylation of RNA to assess expression dynamics. Nat Methods. 2017;14:1198-1204 pubmed publisher |
| Vu L, Pickering B, Cheng Y, Zaccara S, Nguyen D, Minuesa G, et al. The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. Nat Med. 2017;23:1369-1376 pubmed publisher |
| Liu N, Zhou K, Parisien M, Dai Q, Diatchenko L, Pan T. N6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein. Nucleic Acids Res. 2017;45:6051-6063 pubmed publisher |
| Tirumuru N, Zhao B, Lu W, Lu Z, He C, Wu L. N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression. elife. 2016;5: pubmed publisher |
| Zhou J, Wan J, Gao X, Zhang X, Jaffrey S, Qian S. Dynamic m(6)A mRNA methylation directs translational control of heat shock response. Nature. 2015;526:591-4 pubmed publisher |
| Liu N, Dai Q, Zheng G, He C, Parisien M, Pan T. N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions. Nature. 2015;518:560-4 pubmed publisher |
