| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; loading ...; fig 1e
| Liu J, Liu J, Holmström K, Menazza S, Parks R, Fergusson M, et al. MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload. Cell Rep. 2016;16:1561-1573 pubmed publisher |
- western blot knockout validation; mouse; 1:400; fig 1
| Antony A, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, et al. MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration. Nat Commun. 2016;7:10955 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig e1a
| Paggio A, Checchetto V, Campo A, Menabò R, Di Marco G, Di Lisa F, et al. Identification of an ATP-sensitive potassium channel in mitochondria. Nature. 2019;572:609-613 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 6
| Phillips C, Tsai C, Tsai M. The conserved aspartate ring of MCU mediates MICU1 binding and regulation in the mitochondrial calcium uniporter complex. elife. 2019;8: pubmed publisher |
- western blot; human; 1:300; fig s2
| Vais H, Mallilankaraman K, Mak D, Hoff H, Payne R, Tanis J, et al. EMRE Is a Matrix Ca(2+) Sensor that Governs Gatekeeping of the Mitochondrial Ca(2+) Uniporter. Cell Rep. 2016;14:403-410 pubmed publisher |
| Calvo Rodríguez M, Hou S, Snyder A, Kharitonova E, Russ A, Das S, et al. Increased mitochondrial calcium levels associated with neuronal death in a mouse model of Alzheimer's disease. Nat Commun. 2020;11:2146 pubmed publisher |
| Di Marco G, Vallese F, Jourde B, Bergsdorf C, Sturlese M, De Mario A, et al. A High-Throughput Screening Identifies MICU1 Targeting Compounds. Cell Rep. 2020;30:2321-2331.e6 pubmed publisher |
| Gottschalk B, Klec C, Leitinger G, Bernhart E, Rost R, Bischof H, et al. MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex. Nat Commun. 2019;10:3732 pubmed publisher |
| Niemann J, Zehm C, Waterstradt R, Tiedge M, Baltrusch S. Cytosolic and mitochondrial Ca2+ concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. Cell Calcium. 2019;82:102055 pubmed publisher |
| Koval O, Nguyen E, Santhana V, Fidler T, Sebag S, Rasmussen T, et al. Loss of MCU prevents mitochondrial fusion in G1-S phase and blocks cell cycle progression and proliferation. Sci Signal. 2019;12: pubmed publisher |
| Tomar D, Jaña F, Dong Z, Quinn W, Jadiya P, Breves S, et al. Blockade of MCU-Mediated Ca2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation. Cell Rep. 2019;26:3709-3725.e7 pubmed publisher |
| Xing Y, Wang M, Wang J, Nie Z, Wu G, Yang X, et al. Dimerization of MICU Proteins Controls Ca2+ Influx through the Mitochondrial Ca2+ Uniporter. Cell Rep. 2019;26:1203-1212.e4 pubmed publisher |
| Marchi S, Corricelli M, Branchini A, Vitto V, Missiroli S, Morciano G, et al. Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca2+ levels and tumor growth. EMBO J. 2019;38: pubmed publisher |
| Morra E, Rodrigues P, Jesus I, Do Val Lima P, Ávila R, Zanardo T, et al. Endurance training restores spatially distinct cardiac mitochondrial function and myocardial contractility in ovariectomized rats. Free Radic Biol Med. 2019;130:174-188 pubmed publisher |
| Wettmarshausen J, Goh V, Huang K, Arduino D, Tripathi U, Leimpek A, et al. MICU1 Confers Protection from MCU-Dependent Manganese Toxicity. Cell Rep. 2018;25:1425-1435.e7 pubmed publisher |
| Kamer K, Sancak Y, Fomina Y, Meisel J, Chaudhuri D, Grabarek Z, et al. MICU1 imparts the mitochondrial uniporter with the ability to discriminate between Ca2+ and Mn2+. Proc Natl Acad Sci U S A. 2018;115:E7960-E7969 pubmed publisher |
| Suarez J, Cividini F, Scott B, Lehmann K, Díaz Juárez J, Diemer T, et al. Restoring mitochondrial calcium uniporter expression in diabetic mouse heart improves mitochondrial calcium handling and cardiac function. J Biol Chem. 2018;293:8182-8195 pubmed publisher |
| Zeng F, Chen X, Cui W, Wen W, Lu F, Sun X, et al. RIPK1 Binds MCU to Mediate Induction of Mitochondrial Ca2+ Uptake and Promotes Colorectal Oncogenesis. Cancer Res. 2018;78:2876-2885 pubmed publisher |
| Saita S, Tatsuta T, Lampe P, König T, Ohba Y, Langer T. PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria. EMBO J. 2018;37: pubmed publisher |
| Verma M, Callio J, Otero P, Sekler I, Wills Z, Chu C. Mitochondrial Calcium Dysregulation Contributes to Dendrite Degeneration Mediated by PD/LBD-Associated LRRK2 Mutants. J Neurosci. 2017;37:11151-11165 pubmed publisher |
| Kamer K, Grabarek Z, Mootha V. High-affinity cooperative Ca2+ binding by MICU1-MICU2 serves as an on-off switch for the uniporter. EMBO Rep. 2017;18:1397-1411 pubmed publisher |
| Naon D, Zaninello M, Giacomello M, Varanita T, Grespi F, Lakshminaranayan S, et al. Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum-mitochondria tether. Proc Natl Acad Sci U S A. 2016;113:11249-11254 pubmed |
| de la Fuente S, Fernandez Sanz C, Vail C, Agra E, Holmström K, Sun J, et al. Strategic Positioning and Biased Activity of the Mitochondrial Calcium Uniporter in Cardiac Muscle. J Biol Chem. 2016;291:23343-23362 pubmed |
| Lee Y, Min C, Kim T, Song H, Lim Y, Kim D, et al. Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter. EMBO Rep. 2015;16:1318-33 pubmed publisher |
