This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
product type :
antibody
product name :
Anti-KMT2D antibody produced in rabbit
catalog :
HPA035977
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry
citations: 7
Reference
Li H, Li Q, Lian J, Chu Y, Fang K, Xu A, et al. MLL2 promotes cancer cell lymph node metastasis by interacting with RelA and facilitating STC1 transcription. Cell Signal. 2020;65:109457 pubmed publisher
Toska E, Castel P, Chhangawala S, Arruabarrena Aristorena A, Chan C, Hristidis V, et al. PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression. Cell Rep. 2019;27:294-306.e5 pubmed publisher
Koutsioumpa M, Hatziapostolou M, Polytarchou C, Tolosa E, Almada L, Mahurkar Joshi S, et al. Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming. Gut. 2019;68:1271-1286 pubmed publisher
Hillman R, Celestino J, Terranova C, Beird H, Gumbs C, Little L, et al. KMT2D/MLL2 inactivation is associated with recurrence in adult-type granulosa cell tumors of the ovary. Nat Commun. 2018;9:2496 pubmed publisher
Dhar S, Zhao D, Lin T, Gu B, Pal K, Wu S, et al. MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes. Mol Cell. 2018;70:825-841.e6 pubmed publisher
Lin Shiao E, Lan Y, Coradin M, Anderson A, Donahue G, Simpson C, et al. KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis. Genes Dev. 2018;32:181-193 pubmed publisher
Zhang J, Dominguez Sola D, Hussein S, Lee J, Holmes A, Bansal M, et al. Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis. Nat Med. 2015;21:1190-8 pubmed publisher
product information
Product No. :
HPA035977
Product Name :
Anti-KMT2D antibody produced in rabbit
Host :
rabbit
Conjugate :
unconjugated
Antibody Type :
polyclonal
Applications/Description :
Suitable for immunofluorescence: 0.25-2 μg/mL; immunohistochemistry: 1:200-1:500
Species Reactivity :
human
Storage :
Store at -20°C
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA