product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-SMARCA2 antibody produced in rabbit
catalog :
HPA029981
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:1000; fig 1a
Jelinic P, Schlappe B, Conlon N, Tseng J, Olvera N, Dao F, et al. Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type. Mod Pathol. 2016;29:60-6 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig s4
Jamshidi F, Bashashati A, Shumansky K, Dickson B, Gokgoz N, Wunder J, et al. The genomic landscape of epithelioid sarcoma cell lines and tumours. J Pathol. 2016;238:63-73 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; fig 1
  • western blot; human; fig 5
Karnezis A, Wang Y, Ramos P, Hendricks W, Oliva E, D Angelo E, et al. Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type. J Pathol. 2016;238:389-400 pubmed publisher
Ehrenhöfer Wölfer K, Puchner T, Schwarz C, Rippka J, Blaha Ostermann S, Strobl U, et al. SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines. Sci Rep. 2019;9:11661 pubmed publisher
Farnaby W, Koegl M, Roy M, Whitworth C, Diers E, Trainor N, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019;15:672-680 pubmed publisher
Kubota Y, Arakawa Y, Sekiguchi M, Watanabe K, Hiwatari M, Kishimoto H, et al. A case of malignant rhabdoid tumor mimicking yolk sac tumor. Pediatr Blood Cancer. 2019;66:e27784 pubmed publisher
Jiang W, Dulaimi E, Devarajan K, Parsons T, Wang Q, O Neill R, et al. Intratumoral heterogeneity analysis reveals hidden associations between protein expression losses and patient survival in clear cell renal cell carcinoma. Oncotarget. 2017;8:37423-37434 pubmed publisher
Jiang W, Dulaimi E, Devarajan K, Parsons T, Wang Q, Liao L, et al. Immunohistochemistry Successfully Uncovers Intratumoral Heterogeneity and Widespread Co-Losses of Chromatin Regulators in Clear Cell Renal Cell Carcinoma. PLoS ONE. 2016;11:e0164554 pubmed publisher
Karnezis A, Hoang L, Coatham M, Ravn S, Almadani N, Tessier Cloutier B, et al. Loss of switch/sucrose non-fermenting complex protein expression is associated with dedifferentiation in endometrial carcinomas. Mod Pathol. 2016;29:302-14 pubmed publisher
product information
Product No. :
HPA029981
Product Name :
Anti-SMARCA2 antibody produced in rabbit
Host :
rabbit
Conjugate :
unconjugated
Antibody Type :
polyclonal
Applications/Description :
Suitable for immunofluorescence: 0.25-2 μg/mL; immunohistochemistry: 1:500-1:1000
Species Reactivity :
human
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA