Anti-CMTM6 antibody produced in rabbit | MilliporeSigma HPA026980 product information

product summary

company name :

MilliporeSigma

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science

product type :

antibody

product name :

Anti-CMTM6 antibody produced in rabbit

catalog :

HPA026980

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, western blot knockout validation, immunocytochemistry knockout validation

more info or order :

MilliporeSigma product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; human; 1:500; loading ...; fig 4a immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 1a	Muranushi R, Araki K, Yokobori T, Chingunjav B, Hoshino K, Dolgormaa G, et al. High membrane expression of CMTM6 in hepatocellular carcinoma is associated with tumor recurrence. Cancer Sci. 2021;112:3314-3323 pubmed publisher
immunocytochemistry knockout validation; human; loading ...; fig 2c western blot; human; loading ...; fig 1d	Burr M, Sparbier C, Chan Y, Williamson J, Woods K, Beavis P, et al. CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity. Nature. 2017;549:101-105 pubmed publisher
immunohistochemistry; human; loading ...; fig 1c western blot; human; loading ...; fig 1g, 4e	Liu Y, Li X, Zhang H, Zhang M, Wei Y. HuR up-regulates cell surface PD-L1 via stabilizing CMTM6 transcript in cancer. Oncogene. 2021;40:2230-2242 pubmed publisher
	Chen L, Yang Q, Li Y, Yang L, Liu J, Li H, et al. Targeting CMTM6 Suppresses Stem Cell-Like Properties and Enhances Antitumor Immunity in Head and Neck Squamous Cell Carcinoma. Cancer Immunol Res. 2020;8:179-191 pubmed publisher
	Mezzadra R, Sun C, Jae L, Gomez Eerland R, de Vries E, Wu W, et al. Identification of CMTM6 and CMTM4 as PD-L1 protein regulators. Nature. 2017;549:106-110 pubmed publisher

product information

Product No. :

HPA026980

Product Name :

Anti-CMTM6 antibody produced in rabbit

Host :

rabbit

Conjugate :

unconjugated

Antibody Type :

polyclonal

Applications/Description :

Suitable for immunoblotting: 0.04-0.4 μg/mL; immunohistochemistry: 1:50-1:200; immunofluorescence: 0.25-2 μg/mL

Species Reactivity :

human

Storage :

Store at -20°C

more info or order :

MilliporeSigma product webpage