product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-FUS antibody produced in rabbit
catalog :
HPA008784
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:10,000; loading ...; fig s1a
Matějů D, Franzmann T, Patel A, Kopach A, Boczek E, Maharana S, et al. An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function. EMBO J. 2017;36:1669-1687 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000; fig 5
  • western blot; human; fig 6
Kawakami I, Kobayashi Z, Arai T, Yokota O, Nonaka T, Aoki N, et al. Chorea as a clinical feature of the basophilic inclusion body disease subtype of fused-in-sarcoma-associated frontotemporal lobar degeneration. Acta Neuropathol Commun. 2016;4:36 pubmed publisher
Nolan M, Scott C, Gamarallage M, Lunn D, Carpenter K, McDonough E, et al. Quantitative patterns of motor cortex proteinopathy across ALS genotypes. Acta Neuropathol Commun. 2020;8:98 pubmed publisher
Picchiarelli G, Demestre M, Zuko A, Been M, Higelin J, Dieterlé S, et al. FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis. Nat Neurosci. 2019;22:1793-1805 pubmed publisher
Deshpande D, Higelin J, Schoen M, Vomhof T, Boeckers T, Demestre M, et al. Synaptic FUS Localization During Motoneuron Development and Its Accumulation in Human ALS Synapses. Front Cell Neurosci. 2019;13:256 pubmed publisher
Baskota S, Lopez O, Greenamyre J, Kofler J. Spectrum of tau pathologies in Huntington's disease. Lab Invest. 2018;: pubmed publisher
Mackenzie I, Nicholson A, Sarkar M, Messing J, Purice M, Pottier C, et al. TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics. Neuron. 2017;95:808-816.e9 pubmed publisher
Schoen M, Reichel J, Demestre M, Putz S, Deshpande D, Proepper C, et al. Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons. Front Cell Neurosci. 2015;9:496 pubmed publisher
Ziskin J, Greicius M, Zhu W, Okumu A, Adams C, Plowey E. Neuropathologic analysis of Tyr69His TTR variant meningovascular amyloidosis with dementia. Acta Neuropathol Commun. 2015;3:43 pubmed publisher
Barmada S, Ju S, Arjun A, Batarse A, Archbold H, Peisach D, et al. Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1. Proc Natl Acad Sci U S A. 2015;112:7821-6 pubmed publisher
Nakamura M, Bieniek K, Lin W, Graff Radford N, Murray M, Castanedes Casey M, et al. A truncating SOD1 mutation, p.Gly141X, is associated with clinical and pathologic heterogeneity, including frontotemporal lobar degeneration. Acta Neuropathol. 2015;130:145-57 pubmed publisher
Ferrer I, Legati A, García Monco J, Gomez Beldarrain M, Carmona M, Blanco R, et al. Familial behavioral variant frontotemporal dementia associated with astrocyte-predominant tauopathy. J Neuropathol Exp Neurol. 2015;74:370-9 pubmed publisher
product information
Product No. :
HPA008784
Product Name :
Anti-FUS antibody produced in rabbit
Host :
rabbit
Conjugate :
unconjugated
Antibody Type :
polyclonal
Applications/Description :
Suitable for immunoblotting: 0.04-0.4 μg/mL; immunohistochemistry: 1:1000-1:2500; immunofluorescence: 0.25-2 μg/mL
Species Reactivity :
mouse, rat, human
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA