| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunocytochemistry; human; 1:100; loading ...; fig 2f
- immunohistochemistry; mouse; 1:100; loading ...; fig 4f
- western blot; mouse; 1:1000; loading ...; fig 2g
| Tripathi P, Guo H, Dreser A, Yamoah A, Sechi A, Jesse C, et al. Pathomechanisms of ALS8: altered autophagy and defective RNA binding protein (RBP) homeostasis due to the VAPB P56S mutation. Cell Death Dis. 2021;12:466 pubmed publisher |
- immunocytochemistry; human; loading ...; fig s2b
| Gao G, Zhu C, Liu E, Nabi I. Reticulon and CLIMP-63 regulate nanodomain organization of peripheral ER tubules. PLoS Biol. 2019;17:e3000355 pubmed publisher |
- western blot; mouse; 1:500; loading ...; fig 9f
| Quaranta V, Rainer C, Nielsen S, Raymant M, Ahmed M, Engle D, et al. Macrophage-Derived Granulin Drives Resistance to Immune Checkpoint Inhibition in Metastatic Pancreatic Cancer. Cancer Res. 2018;78:4253-4269 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 1a
- western blot; human; loading ...; fig 1s1c
| Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig 4c
- western blot; mouse; loading ...; fig 4a
| Hubert V, Peschel A, Langer B, Groger M, Rees A, Kain R. LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes. Biol Open. 2016;5:1516-1529 pubmed publisher |
- western blot; mouse; loading ...; fig 1b
- western blot; African green monkey; loading ...; fig 4a
| McLelland G, Lee S, McBride H, Fon E. Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system. J Cell Biol. 2016;214:275-91 pubmed publisher |
- immunocytochemistry; human; fig 1
- western blot; human; fig 1
| Ren H, Elgner F, Jiang B, Himmelsbach K, Medvedev R, Ploen D, et al. The Autophagosomal SNARE Protein Syntaxin 17 Is an Essential Factor for the Hepatitis C Virus Life Cycle. J Virol. 2016;90:5989-6000 pubmed publisher |
| Wang B, Xiao X, Huang F, Liu R. Syntaxin-17-Dependent Mitochondrial Dynamics is Essential for Protection Against Oxidative-Stress-Induced Apoptosis. Antioxidants (Basel). 2019;8: pubmed publisher |
| Gu Y, Princely Abudu Y, Kumar S, Bissa B, Choi S, Jia J, et al. Mammalian Atg8 proteins regulate lysosome and autolysosome biogenesis through SNAREs. EMBO J. 2019;38:e101994 pubmed publisher |
| Tian X, Zheng P, Zhou C, Wang X, Ma H, Ma W, et al. DIPK2A promotes STX17- and VAMP7-mediated autophagosome-lysosome fusion by binding to VAMP7B. Autophagy. 2019;:1-14 pubmed publisher |
| Vats S, Manjithaya R. A reversible autophagy inhibitor blocks autophagosome-lysosome fusion by preventing Stx17 loading onto autophagosomes. Mol Biol Cell. 2019;:mbcE18080482 pubmed publisher |
| Xian H, Yang Q, Xiao L, Shen H, Liou Y. STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism. Nat Commun. 2019;10:2059 pubmed publisher |
| Yang H, Shen H, Li J, Guo L. SIGMAR1/Sigma-1 receptor ablation impairs autophagosome clearance. Autophagy. 2019;:1-19 pubmed publisher |
| Turco E, Witt M, Abert C, Bock Bierbaum T, Su M, Trapannone R, et al. FIP200 Claw Domain Binding to p62 Promotes Autophagosome Formation at Ubiquitin Condensates. Mol Cell. 2019;74:330-346.e11 pubmed publisher |
| Kumar S, Gu Y, Abudu Y, Bruun J, Jain A, Farzam F, et al. Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation. Dev Cell. 2019;: pubmed publisher |
| Xia Y, Liu N, Xie X, Bi G, Ba H, Li L, et al. The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion. Autophagy. 2019;15:960-975 pubmed publisher |
| Wu M, Lao Y, Tan H, Lu G, Ren Y, Zheng Z, et al. Oblongifolin C suppresses lysosomal function independently of TFEB nuclear translocation. Acta Pharmacol Sin. 2019;40:929-937 pubmed publisher |
| Wang C, Wang H, Zhang D, Luo W, Liu R, Xu D, et al. Phosphorylation of ULK1 affects autophagosome fusion and links chaperone-mediated autophagy to macroautophagy. Nat Commun. 2018;9:3492 pubmed publisher |
| Barbero Camps E, Roca Agujetas V, Bartolessis I, de Dios C, Fernandez Checa J, Mari M, et al. Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion. Autophagy. 2018;14:1129-1154 pubmed publisher |
| Matsui T, Jiang P, Nakano S, Sakamaki Y, Yamamoto H, Mizushima N. Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17. J Cell Biol. 2018;217:2633-2645 pubmed publisher |
| Hua R, Han S, Zhang N, Dai Q, Liu T, Li J. cPKC?-Modulated Sequential Reactivation of mTOR Inhibited Autophagic Flux in Neurons Exposed to Oxygen Glucose Deprivation/Reperfusion. Int J Mol Sci. 2018;19: pubmed publisher |
| Kimura H, Arasaki K, Ohsaki Y, Fujimoto T, Ohtomo T, Yamada J, et al. Syntaxin 17 promotes lipid droplet formation by regulating the distribution of acyl-CoA synthetase 3. J Lipid Res. 2018;59:805-819 pubmed publisher |
| Fu R, Deng Q, Zhang H, Hu X, Li Y, Liu Y, et al. A novel autophagy inhibitor berbamine blocks SNARE-mediated autophagosome-lysosome fusion through upregulation of BNIP3. Cell Death Dis. 2018;9:243 pubmed publisher |
| Kumar S, Jain A, Farzam F, Jia J, Gu Y, Choi S, et al. Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins. J Cell Biol. 2018;217:997-1013 pubmed publisher |
| Jung J, Behrends C. Protocol for Establishing a Multiplex Image-based Autophagy RNAi Screen in Cell Cultures. Bio Protoc. 2017;7:27982478 pubmed publisher |
| Uematsu M, Nishimura T, Sakamaki Y, Yamamoto H, Mizushima N. Accumulation of undegraded autophagosomes by expression of dominant-negative STX17 (syntaxin 17) mutants. Autophagy. 2017;13:1452-1464 pubmed publisher |
| Beckerman P, Bi Karchin J, Park A, Qiu C, Dummer P, Soomro I, et al. Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice. Nat Med. 2017;23:429-438 pubmed publisher |
| Kimura T, Jia J, Kumar S, Choi S, Gu Y, Mudd M, et al. Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy. EMBO J. 2017;36:42-60 pubmed publisher |
| Zhen Y, Li W. Impairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33A(D251E) mutation. Autophagy. 2015;11:1608-22 pubmed publisher |
| Diao J, Liu R, Rong Y, Zhao M, Zhang J, Lai Y, et al. ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes. Nature. 2015;520:563-6 pubmed publisher |
