Ng Blichfeldt J, de Jong T, Kortekaas R, Wu X, Lindner M, Guryev V, et al. TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation. Am J Physiol Lung Cell Mol Physiol. 2019;317:L14-L28 pubmed publisher

Saunders V, Lafitte M, Adrados I, Quereda V, Feurstein D, Ling Y, et al. Identification of an EGFRvIII-JNK2-HGF/c-Met-Signaling Axis Required for Intercellular Crosstalk and Glioblastoma Multiforme Cell Invasion. Mol Pharmacol. 2015;88:962-9 pubmed publisher

Nakamura M, Ono Y, Kanemura M, Tanaka T, Hayashi M, Terai Y, et al. Hepatocyte growth factor secreted by ovarian cancer cells stimulates peritoneal implantation via the mesothelial-mesenchymal transition of the peritoneum. Gynecol Oncol. 2015;139:345-54 pubmed publisher

Gao W, Kim H, Ho M. Human Monoclonal Antibody Targeting the Heparan Sulfate Chains of Glypican-3 Inhibits HGF-Mediated Migration and Motility of Hepatocellular Carcinoma Cells. PLoS ONE. 2015;10:e0137664 pubmed publisher

Fagoonee S, Famulari E, Silengo L, Tolosano E, Altruda F. Long Term Liver Engraftment of Functional Hepatocytes Obtained from Germline Cell-Derived Pluripotent Stem Cells. PLoS ONE. 2015;10:e0136762 pubmed publisher

Kherrouche Z, Monte D, Werkmeister E, Stoven L, De Launoit Y, Cortot A, et al. PEA3 transcription factors are downstream effectors of Met signaling involved in migration and invasiveness of Met-addicted tumor cells. Mol Oncol. 2015;9:1852-67 pubmed publisher

Husmann K, Ducommun P, Sabile A, Pedersen E, Born W, Fuchs B. Signal transduction and downregulation of C-MET in HGF stimulated low and highly metastatic human osteosarcoma cells. Biochem Biophys Res Commun. 2015;464:1222-1227 pubmed publisher

Peron M, Lovisa F, Poli E, Basso G, Bonvini P. Understanding the Interplay between Expression, Mutation and Activity of ALK Receptor in Rhabdomyosarcoma Cells for Clinical Application of Small-Molecule Inhibitors. PLoS ONE. 2015;10:e0132330 pubmed publisher

Xie C, Sun H, Wang F, Li Z, Yin Y, Fang Q, et al. Integrated analysis of gene expression and DNA methylation changes induced by hepatocyte growth factor in human hepatocytes. Mol Med Rep. 2015;12:4250-4258 pubmed publisher

Ren X, Meng Z, Yang H, Li H, Xu K, Zheng W, et al. Synergistic Effects of Combining Anti-Midkine and Hepatocyte Growth Factor Therapies Against Diabetic Nephropathy in Rats. Am J Med Sci. 2015;350:47-54 pubmed publisher

Wu H, Fan F, Liu Z, Shen C, Wang A, Lu Y. Norcantharidin combined with EGFR-TKIs overcomes HGF-induced resistance to EGFR-TKIs in EGFR mutant lung cancer cells via inhibition of Met/PI3k/Akt pathway. Cancer Chemother Pharmacol. 2015;76:307-15 pubmed publisher

Ozawa Y, Nakamura Y, Fujishima F, Felizola S, Takeda K, Okamoto H, et al. c-Met in esophageal squamous cell carcinoma: an independent prognostic factor and potential therapeutic target. BMC Cancer. 2015;15:451 pubmed publisher

Bill K, Garnett J, Ma X, May C, Bolshakov S, Lazar A, et al. The hepatocyte growth factor receptor as a potential therapeutic target for dedifferentiated liposarcoma. Lab Invest. 2015;95:951-61 pubmed publisher

Montagne R, Berbon M, Doublet L, Debreuck N, Baranzelli A, Drobecq H, et al. Necrosis- and apoptosis-related Met cleavages have divergent functional consequences. Cell Death Dis. 2015;6:e1769 pubmed publisher

Furcht C, Buonato J, Lazzara M. EGFR-activated Src family kinases maintain GAB1-SHP2 complexes distal from EGFR. Sci Signal. 2015;8:ra46 pubmed publisher

Wang L, Lin L, Chen X, Sun L, Liao Y, Huang N, et al. Metastasis-associated in colon cancer-1 promotes vasculogenic mimicry in gastric cancer by upregulating TWIST1/2. Oncotarget. 2015;6:11492-506 pubmed

Zoratti G, Tanabe L, Varela F, Murray A, Bergum C, Colombo Ã, et al. Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling. Nat Commun. 2015;6:6776 pubmed publisher

Ohta K, Hoshino H, Wang J, Ono S, Iida Y, Hata K, et al. MicroRNA-93 activates c-Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A. Oncotarget. 2015;6:3211-24 pubmed

Chang J, Wang S, Zhang Z, Liu X, Wu Z, Geng R, et al. Multiple receptor tyrosine kinase activation attenuates therapeutic efficacy of the fibroblast growth factor receptor 2 inhibitor AZD4547 in FGFR2 amplified gastric cancer. Oncotarget. 2015;6:2009-22 pubmed

Heffernan J, Overstreet D, Le L, Vernon B, Sirianni R. Bioengineered Scaffolds for 3D Analysis of Glioblastoma Proliferation and Invasion. Ann Biomed Eng. 2015;43:1965-77 pubmed publisher

Steward O, Sharp K, Yee K, Hatch M, Bonner J. Characterization of ectopic colonies that form in widespread areas of the nervous system with neural stem cell transplants into the site of a severe spinal cord injury. J Neurosci. 2014;34:14013-21 pubmed publisher

Cazet A, Charest J, Bennett D, Sambrooks C, Contessa J. Mannose phosphate isomerase regulates fibroblast growth factor receptor family signaling and glioma radiosensitivity. PLoS ONE. 2014;9:e110345 pubmed publisher

Kikkawa Y, Nakagawa T, Ying L, Tabata Y, Tsubouchi H, Ido A, et al. Growth factor-eluting cochlear implant electrode: impact on residual auditory function, insertional trauma, and fibrosis. J Transl Med. 2014;12:280 pubmed publisher

Koh S, Kim M, Lee K, Kim S, Kim J. RhoGDI2 is associated with HGF-mediated tumor invasion through VEGF in stomach cancer. Clin Exp Metastasis. 2014;31:805-15 pubmed publisher

Kanteti R, Dhanasingh I, Kawada I, Lennon F, Arif Q, Bueno R, et al. MET and PI3K/mTOR as a potential combinatorial therapeutic target in malignant pleural mesothelioma. PLoS ONE. 2014;9:e105919 pubmed publisher

Pennacchietti S, Cazzanti M, Bertotti A, Rideout W, Han M, Gyuris J, et al. Microenvironment-derived HGF overcomes genetically determined sensitivity to anti-MET drugs. Cancer Res. 2014;74:6598-609 pubmed publisher

Gangemi R, Amaro A, Gino A, Barisione G, Fabbi M, Pfeffer U, et al. ADAM10 correlates with uveal melanoma metastasis and promotes in vitro invasion. Pigment Cell Melanoma Res. 2014;27:1138-48 pubmed publisher

Zhou J, Chen X, Zhao J, Bao Z, Chen X, Zhang P, et al. MicroRNA-34a overcomes HGF-mediated gefitinib resistance in EGFR mutant lung cancer cells partly by targeting MET. Cancer Lett. 2014;351:265-71 pubmed publisher

Zhang Z, Wang J, Ji D, Wang C, Liu R, Wu Z, et al. Functional genetic approach identifies MET, HER3, IGF1R, INSR pathways as determinants of lapatinib unresponsiveness in HER2-positive gastric cancer. Clin Cancer Res. 2014;20:4559-73 pubmed publisher

Tsai P, Chu C, Chiu C, Chang L, Lin S. Cardiotoxin III suppresses hepatocyte growth factor-stimulated migration and invasion of MDA-MB-231 cells. Cell Biochem Funct. 2014;32:485-95 pubmed publisher

Tsai P, Chu C, Tseng C, Chen Y, Chang L, Lin S. Inhibitory action of naphtho[1,2-b]furan-4,5-dione on hepatocyte growth factor-induced migration and invasion of MDA-MB-231 cells: mechanisms of action. Clin Exp Pharmacol Physiol. 2014;41:716-26 pubmed publisher

Patnaik A, Weiss G, Papadopoulos K, Hofmeister C, Tibes R, Tolcher A, et al. Phase I ficlatuzumab monotherapy or with erlotinib for refractory advanced solid tumours and multiple myeloma. Br J Cancer. 2014;111:272-80 pubmed publisher

Arlov Ø, Aachmann F, Sundan A, Espevik T, Skjåk Bræk G. Heparin-like properties of sulfated alginates with defined sequences and sulfation degrees. Biomacromolecules. 2014;15:2744-50 pubmed publisher

Oppelt A, Haugsten E, Zech T, Danielsen H, Sveen A, Lobert V, et al. PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1. Biochem J. 2014;461:383-90 pubmed publisher

Lim Y, Kang H, Moon J. C-Met pathway promotes self-renewal and tumorigenecity of head and neck squamous cell carcinoma stem-like cell. Oral Oncol. 2014;50:633-9 pubmed publisher

Ménard L, Parker P, Kermorgant S. Receptor tyrosine kinase c-Met controls the cytoskeleton from different endosomes via different pathways. Nat Commun. 2014;5:3907 pubmed publisher

Pannem R, Dorn C, Hellerbrand C, Massoumi R. Cylindromatosis gene CYLD regulates hepatocyte growth factor expression in hepatic stellate cells through interaction with histone deacetylase 7. Hepatology. 2014;60:1066-81 pubmed publisher

Diem M, Hyun L, Yi F, Hippensteel R, Kuhar E, Lowenstein C, et al. Selection of high-affinity Centyrin FN3 domains from a simple library diversified at a combination of strand and loop positions. Protein Eng Des Sel. 2014;27:419-29 pubmed publisher

Liu J, Pan G, Liang T, Huang P. HGF/c-Met signaling mediated mesenchymal stem cell-induced liver recovery in intestinal ischemia reperfusion model. Int J Med Sci. 2014;11:626-33 pubmed publisher

Ito Y, Correll K, Schiel J, Finigan J, Prekeris R, Mason R. Lung fibroblasts accelerate wound closure in human alveolar epithelial cells through hepatocyte growth factor/c-Met signaling. Am J Physiol Lung Cell Mol Physiol. 2014;307:L94-105 pubmed publisher

Sharp K, Yee K, Steward O. A re-assessment of long distance growth and connectivity of neural stem cells after severe spinal cord injury. Exp Neurol. 2014;257:186-204 pubmed publisher

Nakagawa T, Matsushima T, Kawano S, Nakazawa Y, Kato Y, Adachi Y, et al. Lenvatinib in combination with golvatinib overcomes hepatocyte growth factor pathway-induced resistance to vascular endothelial growth factor receptor inhibitor. Cancer Sci. 2014;105:723-30 pubmed publisher

Fang J, Lee S. Matriptase is required for the active form of hepatocyte growth factor induced Met, focal adhesion kinase and protein kinase B activation on neural stem/progenitor cell motility. Biochim Biophys Acta. 2014;1843:1285-94 pubmed publisher

Tabernero J, Elez M, Herranz M, Rico I, Prudkin L, Andreu J, et al. A pharmacodynamic/pharmacokinetic study of ficlatuzumab in patients with advanced solid tumors and liver metastases. Clin Cancer Res. 2014;20:2793-804 pubmed publisher

Kusunoki H, Taniyama Y, Otsu R, Rakugi H, Morishita R. Anti-inflammatory effects of hepatocyte growth factor on the vicious cycle of macrophages and adipocytes. Hypertens Res. 2014;37:500-6 pubmed publisher

Meng L, Shu M, Chen Y, Yang D, He Q, Zhao H, et al. A novel lead compound CM-118: antitumor activity and new insight into the molecular mechanism and combination therapy strategy in c-Met- and ALK-dependent cancers. Cancer Biol Ther. 2014;15:721-34 pubmed publisher

Liu H, Yang Y, Xiao J, Yang S, Liu Y, Kang W, et al. Semaphorin 4D expression is associated with a poor clinical outcome in cervical cancer patients. Microvasc Res. 2014;93:1-8 pubmed publisher

Valletta D, Czech B, Spruss T, Ikenberg K, Wild P, Hartmann A, et al. Regulation and function of the atypical cadherin FAT1 in hepatocellular carcinoma. Carcinogenesis. 2014;35:1407-15 pubmed publisher

Isono K, Jono H, Ohya Y, Shiraki N, Yamazoe T, Sugasaki A, et al. Generation of familial amyloidotic polyneuropathy-specific induced pluripotent stem cells. Stem Cell Res. 2014;12:574-83 pubmed publisher

Kim J, Kim W, Sung Y, Kwack M, Song S, Choi J, et al. The molecular mechanism underlying the proliferating and preconditioning effect of vitamin C on adipose-derived stem cells. Stem Cells Dev. 2014;23:1364-76 pubmed publisher

Okada M, Ishkitiev N, Yaegaki K, Imai T, Tanaka T, Fukuda M, et al. Hydrogen sulphide increases hepatic differentiation of human tooth pulp stem cells compared with human bone marrow stem cells. Int Endod J. 2014;47:1142-50 pubmed publisher

Mahtouk K, Tjin E, Spaargaren M, Pals S. The HGF/MET pathway as target for the treatment of multiple myeloma and B-cell lymphomas. Biochim Biophys Acta. 2010;1806:208-19 pubmed publisher

Inada M, Follenzi A, Cheng K, Surana M, Joseph B, Benten D, et al. Phenotype reversion in fetal human liver epithelial cells identifies the role of an intermediate meso-endodermal stage before hepatic maturation. J Cell Sci. 2008;121:1002-13 pubmed publisher

Yang S. Gene amplifications at chromosome 7 of the human gastric cancer genome. Int J Mol Med. 2007;20:225-31 pubmed

Nakamura T, Nishizawa T, Hagiya M, Seki T, Shimonishi M, Sugimura A, et al. Molecular cloning and expression of human hepatocyte growth factor. Nature. 1989;342:440-3 pubmed

Rubin J, Chan A, Bottaro D, Burgess W, Taylor W, Cech A, et al. A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor. Proc Natl Acad Sci U S A. 1991;88:415-9 pubmed