This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Tumor Necrosis Factor-α human
catalog :
H8916
citations: 117
Reference
Bruikman C, Vreeken D, Hoogeveen R, Bom M, Danad I, Pinto Sietsma S, et al. Netrin-1 and the Grade of Atherosclerosis Are Inversely Correlated in Humans. Arterioscler Thromb Vasc Biol. 2020;40:462-472 pubmed publisher
Yang S, Wang J, Guo S, Huang D, Lorigados I, Nie X, et al. Transcriptional activation of USP16 gene expression by NFκB signaling. Mol Brain. 2019;12:120 pubmed publisher
Kouam P, Rezniczek G, Adamietz I, Buhler H. Ionizing radiation increases the endothelial permeability and the transendothelial migration of tumor cells through ADAM10-activation and subsequent degradation of VE-cadherin. BMC Cancer. 2019;19:958 pubmed publisher
Fan X, Yan K, Meng Q, Sun R, Yang X, Yuan D, et al. Abnormal expression of SIRTs in psoriasis: Decreased expression of SIRT 1-5 and increased expression of SIRT 6 and 7. Int J Mol Med. 2019;44:157-171 pubmed publisher
Zhu X, Liu Y, Yu J, Du J, Guo R, Feng Y, et al. LncRNA HOXA-AS2 represses endothelium inflammation by regulating the activity of NF-κB signaling. Atherosclerosis. 2019;281:38-46 pubmed publisher
Zhu X, Du J, Yu J, Guo R, Feng Y, Qiao L, et al. LncRNA NKILA regulates endothelium inflammation by controlling a NF-κB/KLF4 positive feedback loop. J Mol Cell Cardiol. 2019;126:60-69 pubmed publisher
Ham Y, Song H, Kwon J, Jeon H, Baek H, Kim C, et al. Effects of fermented Sorghum bicolor L. Moench extract on inflammation and thickness in a vascular cell and atherosclerotic mice model. J Nat Med. 2019;73:34-46 pubmed publisher
Buchrieser J, Oliva Martin M, Moore M, Long J, Cowley S, Perez Simon J, et al. RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation. Cell Death Dis. 2018;9:973 pubmed publisher
Schotte H, Schmidt H, Gaubitz M, Drynda S, Kekow J, Willeke P, et al. Interleukin-6 promoter haplotypes are associated with etanercept response in patients with rheumatoid arthritis. Clin Rheumatol. 2015;34:2021-8 pubmed publisher
Harris K, Coyne C. Unc93b Induces Apoptotic Cell Death and Is Cleaved by Host and Enteroviral Proteases. PLoS ONE. 2015;10:e0141383 pubmed publisher
Yang P, Chiang T, Hsieh C, Huang Y, Wong L, Hung M, et al. The effect of ephrin-A1 on resistance to Photofrin-mediated photodynamic therapy in esophageal squamous cell carcinoma cells. Lasers Med Sci. 2015;30:2353-61 pubmed publisher
Ohana O, Ozer J, Prinsloo I, Benharroch D, Gopas J. Hodgkin lymphoma cell lines bind to platelets. Incubation with platelets induces CD15 and P-selectin dependent adhesion of the cell lines to Human Umbilical Vein Endothelial cells (HUVEC). Cancer Biol Ther. 2015;16:1651-9 pubmed publisher
Goodall L, Ovecka M, Rycroft D, Friel S, Sanderson A, Mistry P, et al. Pharmacokinetic and Pharmacodynamic Characterisation of an Anti-Mouse TNF Receptor 1 Domain Antibody Formatted for In Vivo Half-Life Extension. PLoS ONE. 2015;10:e0137065 pubmed publisher
Cataldi M, Shah N, Felt S, Grdzelishvili V. Breaking resistance of pancreatic cancer cells to an attenuated vesicular stomatitis virus through a novel activity of IKK inhibitor TPCA-1. Virology. 2015;485:340-54 pubmed publisher
Wilhelmsen K, Xu F, Farrar K, Tran A, Khakpour S, Sundar S, et al. Extracellular signal-regulated kinase 5 promotes acute cellular and systemic inflammation. Sci Signal. 2015;8:ra86 pubmed publisher
Mahata B, Biswas S, Rayman P, Chahlavi A, Ko J, Bhattacharjee A, et al. GBM Derived Gangliosides Induce T Cell Apoptosis through Activation of the Caspase Cascade Involving Both the Extrinsic and the Intrinsic Pathway. PLoS ONE. 2015;10:e0134425 pubmed publisher
Peters E, Geraci S, Heemskerk S, Wilmer M, Bilos A, Kraenzlin B, et al. Alkaline phosphatase protects against renal inflammation through dephosphorylation of lipopolysaccharide and adenosine triphosphate. Br J Pharmacol. 2015;172:4932-45 pubmed publisher
Tian X, Xu L, Wang P. MiR-191 inhibits TNF-α induced apoptosis of ovarian endometriosis and endometrioid carcinoma cells by targeting DAPK1. Int J Clin Exp Pathol. 2015;8:4933-42 pubmed
Croes M, Oner F, Kruyt M, Blokhuis T, Bastian O, Dhert W, et al. Proinflammatory Mediators Enhance the Osteogenesis of Human Mesenchymal Stem Cells after Lineage Commitment. PLoS ONE. 2015;10:e0132781 pubmed publisher
Zhou Y, Yamada N, Tanaka T, Hori T, Yokoyama S, Hayakawa Y, et al. Crucial roles of RSK in cell motility by catalysing serine phosphorylation of EphA2. Nat Commun. 2015;6:7679 pubmed publisher
Rom S, Dykstra H, Zuluaga Ramirez V, Reichenbach N, Persidsky Y. miR-98 and let-7g* protect the blood-brain barrier under neuroinflammatory conditions. J Cereb Blood Flow Metab. 2015;35:1957-65 pubmed publisher
He D, Kou X, Yang R, Liu D, Wang X, Luo Q, et al. M1-like Macrophage Polarization Promotes Orthodontic Tooth Movement. J Dent Res. 2015;94:1286-94 pubmed publisher
Jeon Y, Kee J, Kim D, Han Y, Kim S, Kim S, et al. Effects of Ixeris dentata water extract and caffeic acid on allergic inflammation in vivo and in vitro. BMC Complement Altern Med. 2015;15:196 pubmed publisher
Watson R, Buck J, Levin L, Winger R, Wang J, Arase H, et al. Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration. J Exp Med. 2015;212:1021-41 pubmed publisher
Xue Q, Lu Y, Eisele M, Sulistijo E, Khan N, Fan R, et al. Analysis of single-cell cytokine secretion reveals a role for paracrine signaling in coordinating macrophage responses to TLR4 stimulation. Sci Signal. 2015;8:ra59 pubmed publisher
Zhao J, Zhao D, Poage G, Mazumdar A, Zhang Y, Hill J, et al. Death-associated protein kinase 1 promotes growth of p53-mutant cancers. J Clin Invest. 2015;125:2707-20 pubmed publisher
Boosani C, Dhar K, Agrawal D. Down-regulation of hsa-miR-1264 contributes to DNMT1-mediated silencing of SOCS3. Mol Biol Rep. 2015;42:1365-76 pubmed publisher
Liu C, Mei W, Tang J, Yuan Q, Huang L, Lu M, et al. Mefunidone attenuates tubulointerstitial fibrosis in a rat model of unilateral ureteral obstruction. PLoS ONE. 2015;10:e0129283 pubmed publisher
Li S, Wang J, He W, Feng S, Li Y, Wang X, et al. Thioredoxin 2 Is a Novel E2-Interacting Protein That Inhibits the Replication of Classical Swine Fever Virus. J Virol. 2015;89:8510-24 pubmed publisher
Brito H, Martins A, Lavrado J, Mendes E, Francisco A, Santos S, et al. Targeting KRAS Oncogene in Colon Cancer Cells with 7-Carboxylate Indolo[3,2-b]quinoline Tri-Alkylamine Derivatives. PLoS ONE. 2015;10:e0126891 pubmed publisher
Fraser R, Whitley G, Thilaganathan B, Cartwright J. Decidual natural killer cells regulate vessel stability: implications for impaired spiral artery remodelling. J Reprod Immunol. 2015;110:54-60 pubmed publisher
Fauster A, Rebsamen M, Huber K, Bigenzahn J, Stukalov A, Lardeau C, et al. A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis. Cell Death Dis. 2015;6:e1767 pubmed publisher
Wu Z, Huang X, Burton A, Swift K. Glycoprotein labeling with click chemistry (GLCC) and carbohydrate detection. Carbohydr Res. 2015;412:1-6 pubmed publisher
Marshall D, Lyman S, McCauley S, Kovalenko M, Spangler R, Liu C, et al. Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer. PLoS ONE. 2015;10:e0127063 pubmed publisher
Maiuri A, Breier A, Gora L, Parkins R, Ganey P, Roth R. Cytotoxic Synergy Between Cytokines and NSAIDs Associated With Idiosyncratic Hepatotoxicity Is Driven by Mitogen-Activated Protein Kinases. Toxicol Sci. 2015;146:265-80 pubmed publisher
Wang L, Tai C, Chien C, Chiang F, Chen J. Vitamin D decreases the secretion of matrix metalloproteinase-2 and matrix metalloproteinase-9 in fibroblasts derived from Taiwanese patients with chronic rhinosinusitis with nasal polyposis. Kaohsiung J Med Sci. 2015;31:235-40 pubmed publisher
Li L, Ryoo J, Lee K, Choi B, Baek K. Genetic variation in the Mcp-1 gene promoter associated with the risk of polycystic ovary syndrome. PLoS ONE. 2015;10:e0123045 pubmed publisher
Dong C, He M, Tu W, Konishi T, Liu W, Xie Y, et al. The differential role of human macrophage in triggering secondary bystander effects after either gamma-ray or carbon beam irradiation. Cancer Lett. 2015;363:92-100 pubmed publisher
Walter B, Purmessur D, Likhitpanichkul M, Weinberg A, Cho S, Qureshi S, et al. Inflammatory Kinetics and Efficacy of Anti-inflammatory Treatments on Human Nucleus Pulposus Cells. Spine (Phila Pa 1976). 2015;40:955-63 pubmed publisher
Mamat U, Wilke K, Bramhill D, Schromm A, Lindner B, Kohl T, et al. Detoxifying Escherichia coli for endotoxin-free production of recombinant proteins. Microb Cell Fact. 2015;14:57 pubmed publisher
Cristofanon S, Abhari B, Krueger M, Tchoghandjian A, Momma S, Calaminus C, et al. Identification of RIP1 as a critical mediator of Smac mimetic-mediated sensitization of glioblastoma cells for Drozitumab-induced apoptosis. Cell Death Dis. 2015;6:e1724 pubmed publisher
Xu P, Lin S, Yang X, Gu D, Yan T, Wei L, et al. C-reactive protein enhances activation of coagulation system and inflammatory response through dissociating into monomeric form in antineutrophil cytoplasmic antibody-associated vasculitis. BMC Immunol. 2015;16:10 pubmed publisher
Seu L, Sabbaj S, Duverger A, Wagner F, Anderson J, Davies E, et al. Stable Phenotypic Changes of the Host T Cells Are Essential to the Long-Term Stability of Latent HIV-1 Infection. J Virol. 2015;89:6656-72 pubmed publisher
Jungck D, Knobloch J, Körber S, Lin Y, Konradi J, Yanik S, et al. Endothelin receptor B protects granulocyte macrophage colony-stimulating factor mRNA from degradation. J Pharmacol Exp Ther. 2015;353:564-72 pubmed publisher
Yano C, Saeki H, Komine M, Kagami S, Tsunemi Y, Ohtsuki M, et al. Mechanism of Macrophage-Derived Chemokine/CCL22 Production by HaCaT Keratinocytes. Ann Dermatol. 2015;27:152-6 pubmed publisher
Ng C, Fong L, Sulaiman M, Moklas M, Yong Y, Hakim M, et al. Interferon-Gamma Increases Endothelial Permeability by Causing Activation of p38 MAP Kinase and Actin Cytoskeleton Alteration. J Interferon Cytokine Res. 2015;35:513-22 pubmed publisher
Lv Q, Zhen Q, Liu L, Gao R, Yang S, Zhou H, et al. AMP-kinase pathway is involved in tumor necrosis factor alpha-induced lipid accumulation in human hepatoma cells. Life Sci. 2015;131:23-9 pubmed publisher
Wang J, Cao S, Wang A, To E, Law G, Gao J, et al. CFH Y402H polymorphism is associated with elevated vitreal GM-CSF and choroidal macrophages in the postmortem human eye. Mol Vis. 2015;21:264-72 pubmed
Dudek Perić A, Ferreira G, Muchowicz A, Wouters J, Prada N, Martin S, et al. Antitumor immunity triggered by melphalan is potentiated by melanoma cell surface-associated calreticulin. Cancer Res. 2015;75:1603-14 pubmed publisher
Fuchs S, Hsieh L, Saarberg W, Erdelmeier C, Wichelhaus T, Schaefer L, et al. Haemanthus coccineus extract and its main bioactive component narciclasine display profound anti-inflammatory activities in vitro and in vivo. J Cell Mol Med. 2015;19:1021-32 pubmed publisher
Beggs K, Maiuri A, Fullerton A, Poulsen K, Breier A, Ganey P, et al. Trovafloxacin-induced replication stress sensitizes HepG2 cells to tumor necrosis factor-alpha-induced cytotoxicity mediated by extracellular signal-regulated kinase and ataxia telangiectasia and Rad3-related. Toxicology. 2015;331:35-46 pubmed publisher
Arcos J, Diangelo L, Scordo J, Sasindran S, Moliva J, Turner J, et al. Lung Mucosa Lining Fluid Modification of Mycobacterium tuberculosis to Reprogram Human Neutrophil Killing Mechanisms. J Infect Dis. 2015;212:948-58 pubmed publisher
de Mare Bredemeijer E, Mancham S, Verstegen M, De Ruiter P, van Gent R, O NEILL D, et al. Human graft-derived mesenchymal stromal cells potently suppress alloreactive T-cell responses. Stem Cells Dev. 2015;24:1436-47 pubmed publisher
Konishi H, Shirabe K, Nakagawara H, Harimoto N, Yamashita Y, Ikegami T, et al. Suppression of silent information regulator 1 activity in noncancerous tissues of hepatocellular carcinoma: Possible association with non-B non-C hepatitis pathogenesis. Cancer Sci. 2015;106:542-9 pubmed publisher
Liu X, Lai F, Yan X, Jiang C, Guo S, Wang C, et al. RIP1 Kinase Is an Oncogenic Driver in Melanoma. Cancer Res. 2015;75:1736-48 pubmed publisher
Enesa K, Moll H, Luong L, Ferran C, Evans P. A20 suppresses vascular inflammation by recruiting proinflammatory signaling molecules to intracellular aggresomes. FASEB J. 2015;29:1869-78 pubmed publisher
Martín R, Sánchez B, Urdaci M, Langella P, Suárez J, Bermúdez Humarán L. Effect of iron on the probiotic properties of the vaginal isolate Lactobacillus jensenii CECT 4306. Microbiology. 2015;161:708-18 pubmed publisher
Lee E, Seong D, Seo J, Jeong M, Lee H, Song J. USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics. Cell Death Differ. 2015;22:1463-76 pubmed publisher
Elsheikh E, Younoszai Z, Otgonsuren M, Hunt S, Raybuck B, Younossi Z. Markers of endothelial dysfunction in patients with non-alcoholic fatty liver disease and coronary artery disease. J Gastroenterol Hepatol. 2014;29:1528-34 pubmed
Yousaf N, Low W, Onipinla A, Mein C, Caulfield M, Munroe P, et al. Differences between disease-associated endoplasmic reticulum aminopeptidase 1 (ERAP1) isoforms in cellular expression, interactions with tumour necrosis factor receptor 1 (TNF-R1) and regulation by cytokines. Clin Exp Immunol. 2015;180:289-304 pubmed publisher
Ferreira V, Dizzell S, Nazli A, Kafka J, Mueller K, Nguyen P, et al. Medroxyprogesterone Acetate Regulates HIV-1 Uptake and Transcytosis but Not Replication in Primary Genital Epithelial Cells, Resulting in Enhanced T-Cell Infection. J Infect Dis. 2015;211:1745-56 pubmed publisher
Karlberg H, Tan Y, Mirazimi A. Crimean-Congo haemorrhagic fever replication interplays with regulation mechanisms of apoptosis. J Gen Virol. 2015;96:538-46 pubmed publisher
Snyder N, Golin Bisello F, Gao Y, Blair I, Freeman B, Wendell S. 15-Oxoeicosatetraenoic acid is a 15-hydroxyprostaglandin dehydrogenase-derived electrophilic mediator of inflammatory signaling pathways. Chem Biol Interact. 2015;234:144-53 pubmed publisher
Lee H, Ha H, Lee J, Park S, Jeong S, Shin H. The Leaves of Broussonetia kazinoki Siebold Inhibit Atopic Dermatitis-Like Response on Mite Allergen-Treated Nc/Nga Mice. Biomol Ther (Seoul). 2014;22:438-44 pubmed publisher
Goda S, Kato Y, Domae E, Hayashi H, Tani Ishii N, Iida J, et al. Effects of JNK1/2 on the inflammation cytokine TNF-α-enhanced production of MMP-3 in human dental pulp fibroblast-like cells. Int Endod J. 2015;48:1122-8 pubmed publisher
Ishida M, Shimabukuro M, Yagi S, Nishimoto S, Kozuka C, Fukuda D, et al. MicroRNA-378 regulates adiponectin expression in adipose tissue: a new plausible mechanism. PLoS ONE. 2014;9:e111537 pubmed publisher
Suzuki S, Morimoto S, Fujishiro M, Kawasaki M, Hayakawa K, Miyashita T, et al. Inhibition of the insulin-like growth factor system is a potential therapy for rheumatoid arthritis. Autoimmunity. 2015;48:251-8 pubmed publisher
Lee H, Park W, Ryu H, Jeon N. A microfluidic platform for quantitative analysis of cancer angiogenesis and intravasation. Biomicrofluidics. 2014;8:054102 pubmed publisher
Zennadi R. MEK inhibitors, novel anti-adhesive molecules, reduce sickle red blood cell adhesion in vitro and in vivo, and vasoocclusion in vivo. PLoS ONE. 2014;9:e110306 pubmed publisher
Raulf N, El Attar R, Kulms D, Lecis D, Delia D, Walczak H, et al. Differential response of head and neck cancer cell lines to TRAIL or Smac mimetics is associated with the cellular levels and activity of caspase-8 and caspase-10. Br J Cancer. 2014;111:1955-64 pubmed publisher
Moriyama K, Kukita A, Li Y, Uehara N, Zhang J, Takahashi I, et al. Regulation of osteoclastogenesis through Tim-3: possible involvement of the Tim-3/galectin-9 system in the modulation of inflammatory bone destruction. Lab Invest. 2014;94:1200-11 pubmed publisher
McIntyre B, Kushwah R, Mechael R, Shapovalova Z, Alev C, Bhatia M. Innate immune response of human pluripotent stem cell-derived airway epithelium. Innate Immun. 2015;21:504-11 pubmed publisher
Davaine J, Quillard T, Brion R, Lapérine O, Guyomarch B, Merlini T, et al. Osteoprotegerin, pericytes and bone-like vascular calcification are associated with carotid plaque stability. PLoS ONE. 2014;9:e107642 pubmed publisher
Alexiou P, Papakyriakou A, Ntougkos E, Papaneophytou C, Liepouri F, Mettou A, et al. Rationally designed less toxic SPD-304 analogs and preliminary evaluation of their TNF inhibitory effects. Arch Pharm (Weinheim). 2014;347:798-805 pubmed publisher
Lonati P, Brembilla N, Montanari E, Fontao L, Gabrielli A, Vettori S, et al. High IL-17E and low IL-17C dermal expression identifies a fibrosis-specific motif common to morphea and systemic sclerosis. PLoS ONE. 2014;9:e105008 pubmed publisher
Fukuda S, Kohsaka H, Takayasu A, Yokoyama W, Miyabe C, Miyabe Y, et al. Cannabinoid receptor 2 as a potential therapeutic target in rheumatoid arthritis. BMC Musculoskelet Disord. 2014;15:275 pubmed publisher
Ji W, Yang M, Praggastis A, Li Y, Zhou H, He Y, et al. Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death. PLoS ONE. 2014;9:e103224 pubmed publisher
Eletxigerra U, Martinez Perdiguero J, Merino S, Villalonga R, Pingarrón J, Campuzano S. Amperometric magnetoimmunoassay for the direct detection of tumor necrosis factor alpha biomarker in human serum. Anal Chim Acta. 2014;838:37-44 pubmed publisher
Cisterne A, Baraz R, Khan N, Welschinger R, Basnett J, Fung C, et al. Silencer of death domains controls cell death through tumour necrosis factor-receptor 1 and caspase-10 in acute lymphoblastic leukemia. PLoS ONE. 2014;9:e103383 pubmed publisher
Donlin L, Jayatilleke A, Giannopoulou E, Kalliolias G, Ivashkiv L. Modulation of TNF-induced macrophage polarization by synovial fibroblasts. J Immunol. 2014;193:2373-83 pubmed publisher
Nymo S, Niyonzima N, Espevik T, Mollnes T. Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF. Immunobiology. 2014;219:786-92 pubmed publisher
Chattopadhyay A, Hood B, Conrads T, Redner R. Extrinsic apoptosis is impeded by direct binding of the APL fusion protein NPM-RAR to TRADD. Mol Cancer Res. 2014;12:1283-91 pubmed publisher
Kanellis D, Bursac S, Tsichlis P, Volarevic S, Eliopoulos A. Physical and functional interaction of the TPL2 kinase with nucleophosmin. Oncogene. 2015;34:2516-26 pubmed publisher
Li S, Ren J, Xu N, Zhang J, Geng Q, Cao C, et al. MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor. J Mol Cell Cardiol. 2014;75:49-57 pubmed publisher
Pavlosky A, Lau A, Su Y, Lian D, Huang X, Yin Z, et al. RIPK3-mediated necroptosis regulates cardiac allograft rejection. Am J Transplant. 2014;14:1778-90 pubmed publisher
Lv X, Qiu M, Chen D, Zheng N, Jin Y, Wu Z. Apigenin inhibits enterovirus 71 replication through suppressing viral IRES activity and modulating cellular JNK pathway. Antiviral Res. 2014;109:30-41 pubmed publisher
Jeong M, Kim J, Lee H, Seo S. Calcitriol May Down-Regulate mRNA Over-Expression of Toll-Like Receptor-2 and -4, LL-37 and Proinflammatory Cytokines in Cultured Human Keratinocytes. Ann Dermatol. 2014;26:296-302 pubmed publisher
Manecka D, Lelievre V, Anouar Y. Inhibition of constitutive TNF production is associated with PACAP-mediated differentiation in PC12 cells. FEBS Lett. 2014;588:3008-14 pubmed publisher
Arenaccio C, Chiozzini C, Columba Cabezas S, Manfredi F, Federico M. Cell activation and HIV-1 replication in unstimulated CD4+ T lymphocytes ingesting exosomes from cells expressing defective HIV-1. Retrovirology. 2014;11:46 pubmed publisher
Hamilton K, Phong B, Corey C, Cheng J, Gorentla B, ZHONG X, et al. T cell receptor-dependent activation of mTOR signaling in T cells is mediated by Carma1 and MALT1, but not Bcl10. Sci Signal. 2014;7:ra55 pubmed publisher
Tamarozzi F, Wright H, Johnston K, Edwards S, Turner J, Taylor M. Human filarial Wolbachia lipopeptide directly activates human neutrophils in vitro. Parasite Immunol. 2014;36:494-502 pubmed publisher
Tjin E, Krebbers G, Meijlink K, van de Kasteele W, Rosenberg E, Sanders J, et al. Immune-escape markers in relation to clinical outcome of advanced melanoma patients following immunotherapy. Cancer Immunol Res. 2014;2:538-46 pubmed publisher
Schafer P, Parton A, Capone L, Cedzik D, Brady H, Evans J, et al. Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity. Cell Signal. 2014;26:2016-29 pubmed publisher
Liu M, Saeki K, Matsunobu T, Okuno T, Koga T, Sugimoto Y, et al. 12-Hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor. J Exp Med. 2014;211:1063-78 pubmed publisher
Chu X, Chen W, Li N, Hu X, Du C, Yu S, et al. Cytosolic double-stranded DNA induces nonnecroptotic programmed cell death in trophoblasts via IFI16. J Infect Dis. 2014;210:1476-86 pubmed publisher
Mizrahi K, Ash S, Peled T, Yaniv I, Stein J, Askenasy N. Negative selection by apoptosis enriches progenitors in naïve and expanded human umbilical cord blood grafts. Bone Marrow Transplant. 2014;49:942-9 pubmed publisher
Konieczkowski D, Johannessen C, Abudayyeh O, Kim J, Cooper Z, Piris A, et al. A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors. Cancer Discov. 2014;4:816-27 pubmed publisher
Odobasic D, Yang Y, Muljadi R, O Sullivan K, Kao W, Smith M, et al. Endogenous myeloperoxidase is a mediator of joint inflammation and damage in experimental arthritis. Arthritis Rheumatol. 2014;66:907-17 pubmed publisher
Jeon J, Lee J, Park K, Byun H, Lee H, Lee Y, et al. Brazilin selectively disrupts proximal IL-1 receptor signaling complex formation by targeting an IKK-upstream signaling components. Biochem Pharmacol. 2014;89:515-25 pubmed publisher
Liu J, Ren Y, Kang L, Zhang L. Overexpression of CCN3 inhibits inflammation and progression of atherosclerosis in apolipoprotein E-deficient mice. PLoS ONE. 2014;9:e94912 pubmed publisher
Karakawa M, Komine M, Hanakawa Y, Tsuda H, Sayama K, Tamaki K, et al. CCL27 is downregulated by interferon gamma via epidermal growth factor receptor in normal human epidermal keratinocytes. J Cell Physiol. 2014;229:1935-45 pubmed publisher
Ha J, Shil P, Zhu P, Gu L, Li Q, Chung S. Ocular inflammation and endoplasmic reticulum stress are attenuated by supplementation with grape polyphenols in human retinal pigmented epithelium cells and in C57BL/6 mice. J Nutr. 2014;144:799-806 pubmed publisher
Lee E, Song D, Kim Y, Choi B, Chung Y, Kim S, et al. PTX3 stimulates osteoclastogenesis by increasing osteoblast RANKL production. J Cell Physiol. 2014;229:1744-52 pubmed publisher
Kim B, Oh I, Kim J, Jeon J, Jeon B, Shin J, et al. Anti-inflammatory activity of compounds isolated from Astragalus sinicus L. in cytokine-induced keratinocytes and skin. Exp Mol Med. 2014;46:e87 pubmed publisher
Xiao Y, Sun M, Zhan Z, Ye Y, Huang M, Zou Y, et al. Increased phosphorylation of ezrin is associated with the migration and invasion of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Rheumatology (Oxford). 2014;53:1291-300 pubmed publisher
Fukuyo S, Yamaoka K, Sonomoto K, Oshita K, Okada Y, Saito K, et al. IL-6-accelerated calcification by induction of ROR2 in human adipose tissue-derived mesenchymal stem cells is STAT3 dependent. Rheumatology (Oxford). 2014;53:1282-90 pubmed publisher
Kwon B, Kumar P, Lee H, Zeng L, Walsh K, Fu Q, et al. Aberrant cell cycle reentry in human and experimental inclusion body myositis and polymyositis. Hum Mol Genet. 2014;23:3681-94 pubmed publisher
Vandanmagsar B, Haynie K, Wicks S, Bermudez E, Mendoza T, Ribnicky D, et al. Artemisia dracunculus L. extract ameliorates insulin sensitivity by attenuating inflammatory signalling in human skeletal muscle culture. Diabetes Obes Metab. 2014;16:728-38 pubmed publisher
Shimizu K, Kotera Y, Aruga A, Takeshita N, Katagiri S, Ariizumi S, et al. Postoperative dendritic cell vaccine plus activated T-cell transfer improves the survival of patients with invasive hepatocellular carcinoma. Hum Vaccin Immunother. 2014;10:970-6 pubmed
Alique M, Civantos E, Sanchez Lopez E, Lavoz C, Rayego Mateos S, Rodrígues Díez R, et al. Integrin-linked kinase plays a key role in the regulation of angiotensin II-induced renal inflammation. Clin Sci (Lond). 2014;127:19-31 pubmed publisher
Noyola Martínez N, Díaz L, Zaga Clavellina V, Avila E, Halhali A, Larrea F, et al. Regulation of CYP27B1 and CYP24A1 gene expression by recombinant pro-inflammatory cytokines in cultured human trophoblasts. J Steroid Biochem Mol Biol. 2014;144 Pt A:106-9 pubmed publisher
Kanji S, Das M, Aggarwal R, Lu J, Joseph M, Basu S, et al. Nanofiber-expanded human umbilical cord blood-derived CD34+ cell therapy accelerates murine cutaneous wound closure by attenuating pro-inflammatory factors and secreting IL-10. Stem Cell Res. 2014;12:275-88 pubmed publisher
Wei H, Zhang W, Leboeuf R, Frei B. Copper induces--and copper chelation by tetrathiomolybdate inhibits--endothelial activation in vitro. Redox Rep. 2014;19:40-8 pubmed publisher
Verbeek R, Siersema P, ten Kate F, Fluiter K, Souza R, Vleggaar F, et al. Toll-like receptor 4 activation in Barrett's esophagus results in a strong increase in COX-2 expression. J Gastroenterol. 2014;49:1121-34 pubmed publisher
Neve A, Corrado A, Cantatore F. Immunomodulatory effects of vitamin D in peripheral blood monocyte-derived macrophages from patients with rheumatoid arthritis. Clin Exp Med. 2014;14:275-83 pubmed publisher
Parameswaran N, Patial S. Tumor necrosis factor-? signaling in macrophages. Crit Rev Eukaryot Gene Expr. 2010;20:87-103 pubmed
Winder A, Wohlford Lenane C, Scheetz T, Nardy B, Manzel L, Look D, et al. Differential effects of cytokines and corticosteroids on toll-like receptor 2 expression and activity in human airway epithelia. Respir Res. 2009;10:96 pubmed publisher
product information
Catalog Number :
H8916
Product Name :
Tumor Necrosis Factor-α human
Product Type :
GROWTH FACTORS
Product Group :
Cell Biology
Product Description :
TNF-?, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA