This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
N G -Hydroxy-L-arginine acetate salt
catalog :
H7278
citations: 7
Reference
Bollenbach A, Cordts K, Hanff E, Atzler D, Choe C, Schwedhelm E, et al. Evidence by GC-MS that lysine is an arginase-catalyzed metabolite of homoarginine in vitro and in vivo in humans. Anal Biochem. 2019;577:59-66 pubmed publisher
Pera T, Zuidhof A, Smit M, Menzen M, Klein T, Flik G, et al. Arginase inhibition prevents inflammation and remodeling in a guinea pig model of chronic obstructive pulmonary disease. J Pharmacol Exp Ther. 2014;349:229-38 pubmed publisher
Daghigh F, Fukuto J, Ash D. Inhibition of rat liver arginase by an intermediate in NO biosynthesis, NG-hydroxy-L-arginine: implications for the regulation of nitric oxide biosynthesis by arginase. Biochem Biophys Res Commun. 1994;202:174-80 pubmed
Boucher J, Custot J, Vadon S, Delaforge M, Lepoivre M, Tenu J, et al. N omega-hydroxyl-L-arginine, an intermediate in the L-arginine to nitric oxide pathway, is a strong inhibitor of liver and macrophage arginase. Biochem Biophys Res Commun. 1994;203:1614-21 pubmed
Klatt P, Schmidt K, Uray G, Mayer B. Multiple catalytic functions of brain nitric oxide synthase. Biochemical characterization, cofactor-requirement, and the role of N omega-hydroxy-L-arginine as an intermediate. J Biol Chem. 1993;268:14781-7 pubmed
Pufahl R, Wishnok J, Marletta M. Hydrogen peroxide-supported oxidation of NG-hydroxy-L-arginine by nitric oxide synthase. Biochemistry. 1995;34:1930-41 pubmed
Campos K, Giovanelli J, Kaufman S. Characteristics of the nitric oxide synthase-catalyzed conversion of arginine to N-hydroxyarginine, the first oxygenation step in the enzymic synthesis of nitric oxide. J Biol Chem. 1995;270:1721-8 pubmed
product information
Catalog Number :
H7278
Product Name :
N G -Hydroxy-L-arginine acetate salt
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA