This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Interleukin-2 human
catalog :
H7041
citations: 126
Reference
Sarracino A, Gharu L, Kula A, Pasternak A, Avettand Fenoel V, Rouzioux C, et al. Posttranscriptional Regulation of HIV-1 Gene Expression during Replication and Reactivation from Latency by Nuclear Matrix Protein MATR3. MBio. 2018;9: pubmed publisher
Sharma S, Arunachalam P, Menon M, Ragupathy V, Satya R, Jebaraj J, et al. PTAP motif duplication in the p6 Gag protein confers a replication advantage on HIV-1 subtype C. J Biol Chem. 2018;293:11687-11708 pubmed publisher
Schellhorn M, Haustein M, Frank M, Linnebacher M, Hinz B. Celecoxib increases lung cancer cell lysis by lymphokine-activated killer cells via upregulation of ICAM-1. Oncotarget. 2015;6:39342-56 pubmed publisher
Deisting W, Raum T, Kufer P, Baeuerle P, Münz M. Impact of Diverse Immune Evasion Mechanisms of Cancer Cells on T Cells Engaged by EpCAM/CD3-Bispecific Antibody Construct AMG 110. PLoS ONE. 2015;10:e0141669 pubmed publisher
Okita R, Shimizu K, Nojima Y, Yukawa T, Maeda A, Saisho S, et al. Lapatinib enhances trastuzumab-mediated antibody-dependent cellular cytotoxicity via upregulation of HER2 in malignant mesothelioma cells. Oncol Rep. 2015;34:2864-70 pubmed
Zhang Y, Tam J, Mena P, van der Velden A, Bliska J. CCR2+ Inflammatory Dendritic Cells and Translocation of Antigen by Type III Secretion Are Required for the Exceptionally Large CD8+ T Cell Response to the Protective YopE69-77 Epitope during Yersinia Infection. PLoS Pathog. 2015;11:e1005167 pubmed publisher
Salmond R, Brownlie R, Meyuhas O, Zamoyska R. Mechanistic Target of Rapamycin Complex 1/S6 Kinase 1 Signals Influence T Cell Activation Independently of Ribosomal Protein S6 Phosphorylation. J Immunol. 2015;195:4615-22 pubmed publisher
Quast I, Keller C, Maurer M, Giddens J, Tackenberg B, Wang L, et al. Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity. J Clin Invest. 2015;125:4160-70 pubmed publisher
Sanchez C, Baier C, Colle J, Chelbi R, Rihet P, Le Treut T, et al. Natural killer cells in patients with polycythemia vera. Hum Immunol. 2015;76:644-50 pubmed publisher
Ames E, Canter R, Grossenbacher S, Mac S, Smith R, Monjazeb A, et al. Enhanced targeting of stem-like solid tumor cells with radiation and natural killer cells. Oncoimmunology. 2015;4:e1036212 pubmed
Oldreive C, Skowronska A, Davies N, Parry H, Agathanggelou A, Krysov S, et al. T-cell number and subtype influence the disease course of primary chronic lymphocytic leukaemia xenografts in alymphoid mice. Dis Model Mech. 2015;8:1401-12 pubmed publisher
Jahn J, Spielau M, Brandsch C, Stangl G, Delank K, Bähr I, et al. Decreased NK cell functions in obesity can be reactivated by fat mass reduction. Obesity (Silver Spring). 2015;23:2233-41 pubmed publisher
Issekutz A, Derfalvi B, Käsermann F, Rowter D. Potentiation of cytokine-induced proliferation of human Natural Killer cells by intravenous immunoglobulin G. Clin Immunol. 2015;161:373-83 pubmed publisher
Sakamoto N, Ishikawa T, Kokura S, Okayama T, Oka K, Ideno M, et al. Phase I clinical trial of autologous NK cell therapy using novel expansion method in patients with advanced digestive cancer. J Transl Med. 2015;13:277 pubmed publisher
Hiyoshi M, Okuma K, Tateyama S, Takizawa K, Saito M, Kuramitsu M, et al. Furin-dependent CCL17-fused recombinant toxin controls HTLV-1 infection by targeting and eliminating infected CCR4-expressing cells in vitro and in vivo. Retrovirology. 2015;12:73 pubmed publisher
Kim J, Balamurugan A, Azari K, Hofmann C, Ng H, Reed E, et al. Clonal CD8+ T Cell Persistence and Variable Gene Usage Bias in a Human Transplanted Hand. PLoS ONE. 2015;10:e0136235 pubmed publisher
Niu P, Smagul A, Wang L, Sadvakas A, Sha Y, Pérez L, et al. Transcriptional profiling of interleukin-2-primed human adipose derived mesenchymal stem cells revealed dramatic changes in stem cells response imposed by replicative senescence. Oncotarget. 2015;6:17938-57 pubmed
Sakaguchi S, Hainberger D, Tizian C, Tanaka H, Okuda T, Taniuchi I, et al. MAZR and Runx Factors Synergistically Repress ThPOK during CD8+ T Cell Lineage Development. J Immunol. 2015;195:2879-87 pubmed publisher
Sumption N, Goodhead D, Anderson R. Alpha-Particle-Induced Complex Chromosome Exchanges Transmitted through Extra-Thymic Lymphopoiesis In Vitro Show Evidence of Emerging Genomic Instability. PLoS ONE. 2015;10:e0134046 pubmed publisher
Zou Y, Bao J, Pan X, Lu Y, Liao S, Wang X, et al. NKP30-B7-H6 Interaction Aggravates Hepatocyte Damage through Up-Regulation of Interleukin-32 Expression in Hepatitis B Virus-Related Acute-On-Chronic Liver Failure. PLoS ONE. 2015;10:e0134568 pubmed publisher
Scoville S, Keller K, Cheng S, Zhang M, Zhang X, Caligiuri M, et al. Rapid Column-Free Enrichment of Mononuclear Cells from Solid Tissues. Sci Rep. 2015;5:12490 pubmed publisher
Liang L, Zhang Z, Wang Y, Nong L, Zheng Y, Qu L, et al. The Genetic Deletion of 6q21 and PRDM1 and Clinical Implications in Extranodal NK/T Cell Lymphoma, Nasal Type. Biomed Res Int. 2015;2015:435423 pubmed publisher
Godon O, Evlachev A, Bourgine M, Meritet J, Martin P, Inchauspe G, et al. Recognition of core-derived epitopes from a novel HBV-targeted immunotherapeutic by T-cells from patients infected by different viral genotypes. Vaccine. 2015;33:4548-53 pubmed publisher
Bai A, Kokkotou E, Zheng Y, Robson S. Role of acid sphingomyelinase bioactivity in human CD4+ T-cell activation and immune responses. Cell Death Dis. 2015;6:e1828 pubmed publisher
Lisovsky I, Isitman G, Song R, DaFonseca S, Tremblay McLean A, Lebouché B, et al. A Higher Frequency of NKG2A+ than of NKG2A- NK Cells Responds to Autologous HIV-Infected CD4 Cells irrespective of Whether or Not They Coexpress KIR3DL1. J Virol. 2015;89:9909-19 pubmed publisher
Kelsen J, Dawany N, Moran C, Petersen B, Sarmady M, Sasson A, et al. Exome sequencing analysis reveals variants in primary immunodeficiency genes in patients with very early onset inflammatory bowel disease. Gastroenterology. 2015;149:1415-24 pubmed publisher
Pega J, Di Giacomo S, Bucafusco D, Schammas J, Malacari D, Barrionuevo F, et al. Systemic Foot-and-Mouth Disease Vaccination in Cattle Promotes Specific Antibody-Secreting Cells at the Respiratory Tract and Triggers Local Anamnestic Responses upon Aerosol Infection. J Virol. 2015;89:9581-90 pubmed publisher
Schilbach K, Alkhaled M, Welker C, Eckert F, Blank G, Ziegler H, et al. Cancer-targeted IL-12 controls human rhabdomyosarcoma by senescence induction and myogenic differentiation. Oncoimmunology. 2015;4:e1014760 pubmed
Pesce S, Tabellini G, Cantoni C, Patrizi O, Coltrini D, Rampinelli F, et al. B7-H6-mediated downregulation of NKp30 in NK cells contributes to ovarian carcinoma immune escape. Oncoimmunology. 2015;4:e1001224 pubmed
Kreymborg K, Haak S, Murali R, Wei J, Waitz R, Gasteiger G, et al. Ablation of B7-H3 but Not B7-H4 Results in Highly Increased Tumor Burden in a Murine Model of Spontaneous Prostate Cancer. Cancer Immunol Res. 2015;3:849-54 pubmed publisher
Mikucki M, Fisher D, Matsuzaki J, Skitzki J, Gaulin N, Muhitch J, et al. Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints. Nat Commun. 2015;6:7458 pubmed publisher
Siernicka M, Winiarska M, Bajor M, Firczuk M, Muchowicz A, Bobrowicz M, et al. Adenanthin, a new inhibitor of thiol-dependent antioxidant enzymes, impairs the effector functions of human natural killer cells. Immunology. 2015;146:173-83 pubmed publisher
Shafiee H, Kanakasabapathy M, Juillard F, Keser M, Sadasivam M, Yuksekkaya M, et al. Printed Flexible Plastic Microchip for Viral Load Measurement through Quantitative Detection of Viruses in Plasma and Saliva. Sci Rep. 2015;5:9919 pubmed publisher
Zhang S, Bakshi R, Suneetha P, Fytili P, Antunes D, Vieira G, et al. Frequency, Private Specificity, and Cross-Reactivity of Preexisting Hepatitis C Virus (HCV)-Specific CD8+ T Cells in HCV-Seronegative Individuals: Implications for Vaccine Responses. J Virol. 2015;89:8304-17 pubmed publisher
Odorizzi P, Pauken K, Paley M, Sharpe A, Wherry E. Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells. J Exp Med. 2015;212:1125-37 pubmed publisher
García Gallego S, Díaz L, Jiménez J, Gómez R, de la Mata F, Muñoz Fernández M. HIV-1 antiviral behavior of anionic PPI metallo-dendrimers with EDA core. Eur J Med Chem. 2015;98:139-48 pubmed publisher
McLaren P, Gawanbacht A, Pyndiah N, Krapp C, Hotter D, Kluge S, et al. Identification of potential HIV restriction factors by combining evolutionary genomic signatures with functional analyses. Retrovirology. 2015;12:41 pubmed publisher
Borsa M, Ferreira P, Petry A, Ferreira L, Camargo M, Bou Habib D, et al. HIV infection and antiretroviral therapy lead to unfolded protein response activation. Virol J. 2015;12:77 pubmed publisher
Wojta Stremayr D, Neunkirchner A, Srinivasan B, Trapin D, Schmetterer K, Pickl W. CD8+ T Cell Fate and Function Influenced by Antigen-Specific Virus-Like Nanoparticles Co-Expressing Membrane Tethered IL-2. PLoS ONE. 2015;10:e0126034 pubmed publisher
Ueshima C, Kataoka T, Hirata M, Koyanagi I, Honda T, Tsuruyama T, et al. NKp46 regulates the production of serine proteases and IL-22 in human mast cells in urticaria pigmentosa. Exp Dermatol. 2015;24:675-9 pubmed publisher
Desvignes L, Weidinger C, Shaw P, Vaeth M, Ribierre T, Liu M, et al. STIM1 controls T cell-mediated immune regulation and inflammation in chronic infection. J Clin Invest. 2015;125:2347-62 pubmed publisher
Lampe K, Endale M, Cashman S, Fang H, Mattner J, Hildeman D, et al. Slp-76 is a critical determinant of NK-cell mediated recognition of missing-self targets. Eur J Immunol. 2015;45:2072-83 pubmed publisher
Ling Y, Cypowyj S, Aytekin C, Galicchio M, Camcioglu Y, Nepesov S, et al. Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis. J Exp Med. 2015;212:619-31 pubmed publisher
Litjens N, Boer K, Zuijderwijk J, Klepper M, Peeters A, Prens E, et al. Allogeneic Mature Human Dendritic Cells Generate Superior Alloreactive Regulatory T Cells in the Presence of IL-15. J Immunol. 2015;194:5282-93 pubmed publisher
Zhao P, Ma L, Ji H, Yu L, Feng J, Wang J, et al. The expression of TLR-9, CD86, and CD95 phenotypes in circulating B cells of patients with chronic viral hepatitis B or C before and after antiviral therapy. Mediators Inflamm. 2015;2015:762709 pubmed publisher
Ramstead A, Schepetkin I, Todd K, Loeffelholz J, Berardinelli J, Quinn M, et al. Aging influences the response of T cells to stimulation by the ellagitannin, oenothein B. Int Immunopharmacol. 2015;26:367-77 pubmed publisher
Marusic C, Novelli F, Salzano A, Scaloni A, Benvenuto E, Pioli C, et al. Production of an active anti-CD20-hIL-2 immunocytokine in Nicotiana benthamiana. Plant Biotechnol J. 2016;14:240-51 pubmed publisher
Liu L, Patel B, Ghanem M, Bundoc V, Zheng Z, Morgan R, et al. Novel CD4-Based Bispecific Chimeric Antigen Receptor Designed for Enhanced Anti-HIV Potency and Absence of HIV Entry Receptor Activity. J Virol. 2015;89:6685-94 pubmed publisher
Aurisicchio L, Roscilli G, Marra E, Luberto L, Mancini R, La Monica N, et al. Superior Immunologic and Therapeutic Efficacy of a Xenogeneic Genetic Cancer Vaccine Targeting Carcinoembryonic Human Antigen. Hum Gene Ther. 2015;26:386-98 pubmed publisher
Taniguchi M, Ogiso H, Takeuchi T, Kitatani K, Umehara H, Okazaki T. Lysosomal ceramide generated by acid sphingomyelinase triggers cytosolic cathepsin B-mediated degradation of X-linked inhibitor of apoptosis protein in natural killer/T lymphoma cell apoptosis. Cell Death Dis. 2015;6:e1717 pubmed publisher
Wu Z, Frascaroli G, Bayer C, Schmal T, Mertens T. Interleukin-2 from Adaptive T Cells Enhances Natural Killer Cell Activity against Human Cytomegalovirus-Infected Macrophages. J Virol. 2015;89:6435-41 pubmed publisher
Nagahama K, Eto N, Shimojo T, Kondoh T, Nakahara K, Sakakibara Y, et al. Effect of kumquat (Fortunella crassifolia) pericarp on natural killer cell activity in vitro and in vivo. Biosci Biotechnol Biochem. 2015;79:1327-36 pubmed publisher
Che J, Selin L, Welsh R. Evaluation of non-reciprocal heterologous immunity between unrelated viruses. Virology. 2015;482:89-97 pubmed publisher
Vassena L, Giuliani E, Koppensteiner H, Bolduan S, Schindler M, Doria M. HIV-1 Nef and Vpu Interfere with L-Selectin (CD62L) Cell Surface Expression To Inhibit Adhesion and Signaling in Infected CD4+ T Lymphocytes. J Virol. 2015;89:5687-700 pubmed publisher
Tian X, Zhang A, Qiu C, Wang W, Yang Y, Qiu C, et al. The upregulation of LAG-3 on T cells defines a subpopulation with functional exhaustion and correlates with disease progression in HIV-infected subjects. J Immunol. 2015;194:3873-82 pubmed publisher
Sarhan D, Palma M, Mao Y, Adamson L, Kiessling R, Mellstedt H, et al. Dendritic cell regulation of NK-cell responses involves lymphotoxin-α, IL-12, and TGF-β. Eur J Immunol. 2015;45:1783-93 pubmed publisher
Telwatte S, Hearps A, Johnson A, Latham C, Moore K, Agius P, et al. Silent mutations at codons 65 and 66 in reverse transcriptase alleviate indel formation and restore fitness in subtype B HIV-1 containing D67N and K70R drug resistance mutations. Nucleic Acids Res. 2015;43:3256-71 pubmed publisher
Liu J, Gaj T, Wallen M, Barbas C. Improved cell-penetrating zinc-finger nuclease proteins for precision genome engineering. Mol Ther Nucleic Acids. 2015;4:e232 pubmed publisher
Edri Brami M, Sharoni H, Hayoun D, Skutelsky L, Nemirovsky A, Porgador A, et al. Development of stage-dependent glycans on the Fc domains of IgG antibodies of ALS animals. Exp Neurol. 2015;267:95-106 pubmed publisher
Fenoglio D, Parodi A, Lavieri R, Kalli F, Ferrera F, Tagliamacco A, et al. Immunogenicity of GX301 cancer vaccine: Four (telomerase peptides) are better than one. Hum Vaccin Immunother. 2015;11:838-50 pubmed publisher
Seidel D, Shibina A, Siebert N, Wels W, Reynolds C, Huebener N, et al. Disialoganglioside-specific human natural killer cells are effective against drug-resistant neuroblastoma. Cancer Immunol Immunother. 2015;64:621-34 pubmed publisher
Li G, Wu K, Tao K, Lu X, Ma J, Mao Z, et al. Vasoactive intestinal peptide induces CD14+HLA-DR‑/low myeloid-derived suppressor cells in gastric cancer. Mol Med Rep. 2015;12:760-8 pubmed publisher
Pereboeva L, Harkins L, Wong S, Lamb L. The safety of allogeneic innate lymphocyte therapy for glioma patients with prior cranial irradiation. Cancer Immunol Immunother. 2015;64:551-62 pubmed publisher
Jha S, Chakraborty N, Singh P, Mukherji B, Dorsky D. Knockdown of T-bet expression in Mart-127-35 -specific T-cell-receptor-engineered human CD4(+)  CD25(-) and CD8(+) T cells attenuates effector function. Immunology. 2015;145:124-35 pubmed publisher
Garcia Alonso M, Caballero M, Umpierrez A, Lluch Bernal M, Knaute T, Rodriguez Perez R. Relationships between T cell and IgE/IgG4 epitopes of the Anisakis simplex major allergen Ani s 1. Clin Exp Allergy. 2015;45:994-1005 pubmed publisher
Bengs S, Marttila J, Susi P, Ilonen J. Elicitation of T-cell responses by structural and non-structural proteins of coxsackievirus B4. J Gen Virol. 2015;96:322-30 pubmed publisher
Santegoets K, Wenink M, van den Berg W, Radstake T. Fc gamma receptor IIb on GM-CSF macrophages controls immune complex mediated inhibition of inflammatory signals. PLoS ONE. 2014;9:e110966 pubmed publisher
Ardolino M, Azimi C, Iannello A, Trevino T, Horan L, Zhang L, et al. Cytokine therapy reverses NK cell anergy in MHC-deficient tumors. J Clin Invest. 2014;124:4781-94 pubmed publisher
Rygh C, Wang J, Thuen M, Gras Navarro A, Huuse E, Thorsen F, et al. Dynamic contrast enhanced MRI detects early response to adoptive NK cellular immunotherapy targeting the NG2 proteoglycan in a rat model of glioblastoma. PLoS ONE. 2014;9:e108414 pubmed publisher
Ren Y, Yang B, Yin Y, Leng X, Jiang Y, Zhang L, et al. Aberrant CD200/CD200R1 expression and its potential role in Th17 cell differentiation, chemotaxis and osteoclastogenesis in rheumatoid arthritis. Rheumatology (Oxford). 2015;54:712-21 pubmed publisher
Coffey G, Betz A, DeGuzman F, Pak Y, Inagaki M, Baker D, et al. The novel kinase inhibitor PRT062070 (Cerdulatinib) demonstrates efficacy in models of autoimmunity and B-cell cancer. J Pharmacol Exp Ther. 2014;351:538-48 pubmed publisher
Purdy A, Alvarez Arias D, Oshinsky J, James A, Serebriiskii I, Campbell K. The ap-2 clathrin adaptor mediates endocytosis of an inhibitory killer cell Ig-like receptor in human NK cells. J Immunol. 2014;193:4675-83 pubmed publisher
Kurktschiev P, Raziorrouh B, Schraut W, Backmund M, Wächtler M, Wendtner C, et al. Dysfunctional CD8+ T cells in hepatitis B and C are characterized by a lack of antigen-specific T-bet induction. J Exp Med. 2014;211:2047-59 pubmed publisher
Venner J, Famulski K, Badr D, Hidalgo L, Chang J, Halloran P. Molecular landscape of T cell-mediated rejection in human kidney transplants: prominence of CTLA4 and PD ligands. Am J Transplant. 2014;14:2565-76 pubmed publisher
Ban S, Salzer E, Eibl M, Linder A, Geier C, Santos Valente E, et al. Combined immunodeficiency evolving into predominant CD4+ lymphopenia caused by somatic chimerism in JAK3. J Clin Immunol. 2014;34:941-53 pubmed publisher
Mata M, Vera J, Gerken C, Rooney C, Miller T, Pfent C, et al. Toward immunotherapy with redirected T cells in a large animal model: ex vivo activation, expansion, and genetic modification of canine T cells. J Immunother. 2014;37:407-15 pubmed publisher
Côté Maurais G, Bernier J. Silver and fullerene nanoparticles' effect on interleukin-2-dependent proliferation of CD4 (+) T cells. Toxicol In Vitro. 2014;28:1474-81 pubmed publisher
Wang J, Nanjundappa R, Shameli A, Clemente Casares X, Yamanouchi J, Elliott J, et al. The cross-priming capacity and direct presentation potential of an autoantigen are separable and inversely related properties. J Immunol. 2014;193:3296-307 pubmed publisher
Kim S, Chung H, Lee K, Lim J. Identification of novel epitopes from human papillomavirus type 18 E7 that can sensitize PBMCs of multiple HLA class I against human cervical cancer. J Transl Med. 2014;12:229 pubmed publisher
Au Yeung B, Zikherman J, Mueller J, Ashouri J, Matloubian M, Cheng D, et al. A sharp T-cell antigen receptor signaling threshold for T-cell proliferation. Proc Natl Acad Sci U S A. 2014;111:E3679-88 pubmed publisher
Chudley L, McCann K, Coleman A, Cazaly A, Bidmon N, Britten C, et al. Harmonisation of short-term in vitro culture for the expansion of antigen-specific CD8(+) T cells with detection by ELISPOT and HLA-multimer staining. Cancer Immunol Immunother. 2014;63:1199-211 pubmed publisher
Macleod B, Bedoui S, Hor J, Mueller S, Russell T, Hollett N, et al. Distinct APC subtypes drive spatially segregated CD4+ and CD8+ T-cell effector activity during skin infection with HSV-1. PLoS Pathog. 2014;10:e1004303 pubmed publisher
Bending D, Pesenacker A, Ursu S, Wu Q, Lom H, Thirugnanabalan B, et al. Hypomethylation at the regulatory T cell-specific demethylated region in CD25hi T cells is decoupled from FOXP3 expression at the inflamed site in childhood arthritis. J Immunol. 2014;193:2699-708 pubmed publisher
Yu K, Lee J, Kim H, Hong I, Choi S, Seo Y, et al. A p38 MAPK-mediated alteration of COX-2/PGE2 regulates immunomodulatory properties in human mesenchymal stem cell aging. PLoS ONE. 2014;9:e102426 pubmed publisher
Malecek K, Grigoryan A, Zhong S, Gu W, Johnson L, Rosenberg S, et al. Specific increase in potency via structure-based design of a TCR. J Immunol. 2014;193:2587-99 pubmed publisher
Beverley P, Ruzsics Z, Hey A, Hutchings C, Boos S, Bolinger B, et al. A novel murine cytomegalovirus vaccine vector protects against Mycobacterium tuberculosis. J Immunol. 2014;193:2306-16 pubmed publisher
Arenaccio C, Chiozzini C, Columba Cabezas S, Manfredi F, Affabris E, Baur A, et al. Exosomes from human immunodeficiency virus type 1 (HIV-1)-infected cells license quiescent CD4+ T lymphocytes to replicate HIV-1 through a Nef- and ADAM17-dependent mechanism. J Virol. 2014;88:11529-39 pubmed publisher
Shen Y, Liu Q, Luo Y, Zhang P, Bai F, Cheng S, et al. Enhancement of the cytotoxic activity of cytokine-induced killer cells transfected with IL3PE38KDEL gene against acute myeloid leukemia cells. Ann Hematol. 2014;93:2019-28 pubmed publisher
Wu L, Wang C, Boisson B, Misra S, Rayman P, Finke J, et al. The differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signaling. J Immunol. 2014;193:1590-9 pubmed publisher
Leuenberger T, Pfueller C, Luessi F, Bendix I, Paterka M, Prozorovski T, et al. Modulation of dendritic cell immunobiology via inhibition of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase. PLoS ONE. 2014;9:e100871 pubmed publisher
Otsuki H, Yoneda M, Igarashi T, Miura T. Generation of a monkey-tropic human immunodeficiency virus type 1 carrying env from a CCR5-tropic subtype C clinical isolate. Virology. 2014;460-461:1-10 pubmed publisher
Knowlden S, Capece T, Popovic M, Chapman T, Rezaee F, Kim M, et al. Regulation of T cell motility in vitro and in vivo by LPA and LPA2. PLoS ONE. 2014;9:e101655 pubmed publisher
Martinelli R, Zeiger A, Whitfield M, Sciuto T, Dvorak A, Van Vliet K, et al. Probing the biomechanical contribution of the endothelium to lymphocyte migration: diapedesis by the path of least resistance. J Cell Sci. 2014;127:3720-34 pubmed publisher
Takahashi R, Yamagishi M, Nakano K, Yamochi T, Yamochi T, Fujikawa D, et al. Epigenetic deregulation of Ellis Van Creveld confers robust Hedgehog signaling in adult T-cell leukemia. Cancer Sci. 2014;105:1160-9 pubmed publisher
GUERRERO A, Dong M, Zhao Y, Lau Kilby A, Tarbell K. Interleukin-2-mediated inhibition of dendritic cell development correlates with decreased CD135 expression and increased monocyte/macrophage precursors. Immunology. 2014;143:640-50 pubmed publisher
Gao N, Dresel J, Eckstein V, Gellert R, Störch H, Venigalla R, et al. Impaired suppressive capacity of activation-induced regulatory B cells in systemic lupus erythematosus. Arthritis Rheumatol. 2014;66:2849-61 pubmed publisher
Volpe E, Pattarini L, Martinez Cingolani C, Meller S, Donnadieu M, Bogiatzi S, et al. Thymic stromal lymphopoietin links keratinocytes and dendritic cell-derived IL-23 in patients with psoriasis. J Allergy Clin Immunol. 2014;134:373-81 pubmed publisher
Meager A, Wadhwa M. Detection of anti-cytokine antibodies and their clinical relevance. Expert Rev Clin Immunol. 2014;10:1029-47 pubmed publisher
Pretto F, Elia G, Castioni N, Neri D. Preclinical evaluation of IL2-based immunocytokines supports their use in combination with dacarbazine, paclitaxel and TNF-based immunotherapy. Cancer Immunol Immunother. 2014;63:901-10 pubmed publisher
Zhu S, Phatarpekar P, Denman C, Senyukov V, Somanchi S, Nguyen Jackson H, et al. Transcription of the activating receptor NKG2D in natural killer cells is regulated by STAT3 tyrosine phosphorylation. Blood. 2014;124:403-11 pubmed publisher
Wang H, Wang Y, Jiang X, Wang Z, Zhong B, Fang Y. The molecular mechanism of curcumol on inducing cell growth arrest and apoptosis in Jurkat cells, a model of CD4⁺ T cells. Int Immunopharmacol. 2014;21:375-82 pubmed publisher
Kleijn A, Kloezeman J, Treffers Westerlaken E, Fulci G, Leenstra S, Dirven C, et al. The in vivo therapeutic efficacy of the oncolytic adenovirus Delta24-RGD is mediated by tumor-specific immunity. PLoS ONE. 2014;9:e97495 pubmed publisher
Molfetta R, Quatrini L, Capuano C, Gasparrini F, Zitti B, Zingoni A, et al. c-Cbl regulates MICA- but not ULBP2-induced NKG2D down-modulation in human NK cells. Eur J Immunol. 2014;44:2761-70 pubmed publisher
Traitanon O, Gorbachev A, Bechtel J, Keslar K, Baldwin W, Poggio E, et al. IL-15 induces alloreactive CD28(-) memory CD8 T cell proliferation and CTLA4-Ig resistant memory CD8 T cell activation. Am J Transplant. 2014;14:1277-89 pubmed publisher
Geffner L, Basile J, Yokobori N, Kviatcovsky D, Sabio Y García C, Ritacco V, et al. Mycobacterium tuberculosis multidrug resistant strain M induces an altered activation of cytotoxic CD8+ T cells. PLoS ONE. 2014;9:e97837 pubmed publisher
Valente M, Baey C, Louche P, Dutertre C, Vimeux L, Marañon C, et al. Apoptotic cell capture by DCs induces unexpectedly robust autologous CD4+ T-cell responses. Eur J Immunol. 2014;44:2274-86 pubmed publisher
Breman E, van Miert P, van der Steen D, Heemskerk M, Doxiadis I, Roelen D, et al. HLA monomers as a tool to monitor indirect allorecognition. Transplantation. 2014;97:1119-27 pubmed publisher
Freeman M, Roberts A, Burkum C, Woodland D, Blackman M. Promotion of a subdominant CD8 T cell response during murine gammaherpesvirus 68 infection in the absence of CD4 T cell help. J Virol. 2014;88:7862-9 pubmed publisher
Leipe J, Schramm M, Prots I, Schulze Koops H, Skapenko A. Increased Th17 cell frequency and poor clinical outcome in rheumatoid arthritis are associated with a genetic variant in the IL4R gene, rs1805010. Arthritis Rheumatol. 2014;66:1165-75 pubmed publisher
Cecil D, Holt G, Park K, Gad E, Rastetter L, Childs J, et al. Elimination of IL-10-inducing T-helper epitopes from an IGFBP-2 vaccine ensures potent antitumor activity. Cancer Res. 2014;74:2710-8 pubmed publisher
Lettau M, Kliche S, Kabelitz D, Janssen O. The adapter proteins ADAP and Nck cooperate in T cell adhesion. Mol Immunol. 2014;60:72-9 pubmed publisher
Tong Q, He S, Xie F, Mochizuki K, Liu Y, Mochizuki I, et al. Ezh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice. J Immunol. 2014;192:5012-22 pubmed publisher
Wang D, Feng X, Lu L, Konkel J, Zhang H, Chen Z, et al. A CD8 T cell/indoleamine 2,3-dioxygenase axis is required for mesenchymal stem cell suppression of human systemic lupus erythematosus. Arthritis Rheumatol. 2014;66:2234-45 pubmed publisher
Kizima L, Rodriguez A, Kenney J, Derby N, Mizenina O, Menon R, et al. A potent combination microbicide that targets SHIV-RT, HSV-2 and HPV. PLoS ONE. 2014;9:e94547 pubmed publisher
Drewes J, Szeto G, Engle E, Liao Z, Shearer G, Zink M, et al. Attenuation of pathogenic immune responses during infection with human and simian immunodeficiency virus (HIV/SIV) by the tetracycline derivative minocycline. PLoS ONE. 2014;9:e94375 pubmed publisher
Roider J, Meissner T, Kraut F, Vollbrecht T, Stirner R, Bogner J, et al. Comparison of experimental fine-mapping to in silico prediction results of HIV-1 epitopes reveals ongoing need for mapping experiments. Immunology. 2014;143:193-201 pubmed publisher
Hosoi H, Ikeda H, Imai N, Amaike C, Wang L, Orito Y, et al. Stimulation through very late antigen-4 and -5 improves the multifunctionality and memory formation of CD8⁺ T cells. Eur J Immunol. 2014;44:1747-58 pubmed publisher
Mishra S, Losikoff P, Self A, Terry F, Ardito M, Tassone R, et al. Peptide-pulsed dendritic cells induce the hepatitis C viral epitope-specific responses of naïve human T cells. Vaccine. 2014;32:3285-92 pubmed publisher
Ruan M, Thorn K, Liu S, Li S, Yang W, Zhang C, et al. The secretion of IL-6 by CpG-ODN-treated cancer cells promotes T-cell immune responses partly through the TLR-9/AP-1 pathway in oral squamous cell carcinoma. Int J Oncol. 2014;44:2103-10 pubmed publisher
Rebhandl S, Huemer M, Zaborsky N, Gassner F, Catakovic K, Felder T, et al. Alternative splice variants of AID are not stoichiometrically present at the protein level in chronic lymphocytic leukemia. Eur J Immunol. 2014;44:2175-87 pubmed publisher
God J, Zhao D, Cameron C, Amria S, Bethard J, Haque A. Disruption of HLA class II antigen presentation in Burkitt lymphoma: implication of a 47,000 MW acid labile protein in CD4+ T-cell recognition. Immunology. 2014;142:492-505 pubmed publisher
Guma S, Lee D, Ling Y, Gordon N, Kleinerman E. Aerosol interleukin-2 induces natural killer cell proliferation in the lung and combination therapy improves the survival of mice with osteosarcoma lung metastasis. Pediatr Blood Cancer. 2014;61:1362-8 pubmed publisher
Fujiyama T, Ito T, Ogawa N, Suda T, Tokura Y, Hashizume H. Preferential infiltration of interleukin-4-producing CXCR4+ T cells in the lesional muscle but not skin of patients with dermatomyositis. Clin Exp Immunol. 2014;177:110-20 pubmed publisher
McCarthy S, Jung D, Sakac D, Branch D. c-Src and Pyk2 protein tyrosine kinases play protective roles in early HIV-1 infection of CD4+ T-cell lines. J Acquir Immune Defic Syndr. 2014;66:118-26 pubmed publisher
Xie B, Yang J, Li H, Zhang B, Chen W, Zhou B, et al. Dendritic cells transfected with hepatocellular carcinoma (HCC) total RNA induce specific immune responses against HCC in vitro and in vivo. Clin Transl Oncol. 2014;16:753-60 pubmed publisher
Jacobs S, Plessers J, Pinxteren J, Roobrouck V, Verfaillie C, Van Gool S. Mutual interaction between human multipotent adult progenitor cells and NK cells. Cell Transplant. 2014;23:1099-110 pubmed publisher
product information
Catalog Number :
H7041
Product Name :
Interleukin-2 human
Product Type :
GROWTH FACTORS
Product Group :
Cell Biology
Product Description :
IL-2, recombinant, expressed in HEK 293 cells, cell culture tested, endotoxin tested
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA