Gerakopoulos V, Ngo P, Tsiokas L. Loss of polycystins suppresses deciliation via the activation of the centrosomal integrity pathway. Life Sci Alliance. 2020;3: pubmed publisher

Tasaka G, Feigin L, Maor I, Groysman M, DeNardo L, Schiavo J, et al. The Temporal Association Cortex Plays a Key Role in Auditory-Driven Maternal Plasticity. Neuron. 2020;: pubmed publisher

Hoevenaar W, Janssen A, Quirindongo A, Ma H, Klaasen S, Teixeira A, et al. Degree and site of chromosomal instability define its oncogenic potential. Nat Commun. 2020;11:1501 pubmed publisher

Vitos Faleato J, Real S, Gutierrez Prat N, Villanueva A, Llonch E, Drosten M, et al. Requirement for epithelial p38α in KRAS-driven lung tumor progression. Proc Natl Acad Sci U S A. 2020;117:2588-2596 pubmed publisher

Yoo H, Lee Y, Park C, Son D, Choi D, Park J, et al. Epigenetic priming by Dot1l in lymphatic endothelial progenitors ensures normal lymphatic development and function. Cell Death Dis. 2020;11:14 pubmed publisher

Wall N, Neumann P, BEIER K, Mokhtari A, Luo L, Malenka R. Complementary Genetic Targeting and Monosynaptic Input Mapping Reveal Recruitment and Refinement of Distributed Corticostriatal Ensembles by Cocaine. Neuron. 2019;104:916-930.e5 pubmed publisher

Bok I, Vera O, Xu X, Jasani N, Nakamura K, Reff J, et al. A versatile ES cell-based melanoma mouse modeling platform. Cancer Res. 2019;: pubmed publisher

Ye L, Lin C, Wang X, Li Q, Li Y, Wang M, et al. Epigenetic silencing of SALL2 confers tamoxifen resistance in breast cancer. EMBO Mol Med. 2019;11:e10638 pubmed publisher

Chiang M, Michieletto D, Brackley C, Rattanavirotkul N, Mohammed H, Marenduzzo D, et al. Polymer Modeling Predicts Chromosome Reorganization in Senescence. Cell Rep. 2019;28:3212-3223.e6 pubmed publisher

Wang Y, Wu H, Fontanet P, Codeluppi S, Akkuratova N, Petitpré C, et al. A cell fitness selection model for neuronal survival during development. Nat Commun. 2019;10:4137 pubmed publisher

Zhang H, Alsaleh G, Feltham J, Sun Y, Napolitano G, Riffelmacher T, et al. Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence. Mol Cell. 2019;76:110-125.e9 pubmed publisher

Carvalho C, L Hôte V, Courbeyrette R, Kratassiouk G, Pinna G, Cintrat J, et al. Glucocorticoids delay RAF-induced senescence promoted by EGR1. J Cell Sci. 2019;132: pubmed publisher

Farley B, Morozova E, Dion J, Wang B, Harvey B, Gianni D, et al. Evoked potentials as a translatable biomarker to track functional remyelination. Mol Cell Neurosci. 2019;99:103393 pubmed publisher

Giannotti G, Heinsbroek J, Yue A, Deisseroth K, Peters J. Prefrontal cortex neuronal ensembles encoding fear drive fear expression during long-term memory retrieval. Sci Rep. 2019;9:10709 pubmed publisher

Lionarons D, Hancock D, Rana S, East P, Moore C, Murillo M, et al. RAC1P29S Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance. Cancer Cell. 2019;: pubmed publisher

Hallock H, Quillian H, Mai Y, Maynard K, Hill J, Martinowich K. Manipulation of a genetically and spatially defined sub-population of BDNF-expressing neurons potentiates learned fear and decreases hippocampal-prefrontal synchrony in mice. Neuropsychopharmacology. 2019;: pubmed publisher

Wang W, Ishibashi J, Trefely S, Shao M, Cowan A, Sakers A, et al. A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate. Cell Metab. 2019;: pubmed publisher

Ortiz Sánchez P, Villalba Orero M, López Olañeta M, Larrasa Alonso J, Sanchez Cabo F, Martí Gómez C, et al. Loss of SRSF3 in Cardiomyocytes Leads to Decapping of Contraction-Related mRNAs and Severe Systolic Dysfunction. Circ Res. 2019;125:170-183 pubmed publisher

Matos M, Visser E, Kramvis I, van der Loo R, Gebuis T, Zalm R, et al. Memory strength gates the involvement of a CREB-dependent cortical fear engram in remote memory. Nat Commun. 2019;10:2315 pubmed publisher

Ji J, Min S, Chae S, Ha G, Kim Y, Park Y, et al. De novo phosphorylation of H2AX by WSTF regulates transcription-coupled homologous recombination repair. Nucleic Acids Res. 2019;47:6299-6314 pubmed publisher

Teo Y, Rattanavirotkul N, Olova N, Salzano A, Quintanilla A, Tarrats N, et al. Notch Signaling Mediates Secondary Senescence. Cell Rep. 2019;27:997-1007.e5 pubmed publisher

Caldwell L, Davies N, Cavone L, Mysiak K, Semenova S, Panula P, et al. Regeneration of Dopaminergic Neurons in Adult Zebrafish Depends on Immune System Activation and Differs for Distinct Populations. J Neurosci. 2019;39:4694-4713 pubmed publisher

Mizuhashi K, Nagata M, Matsushita Y, Ono W, Ono N. Growth Plate Borderline Chondrocytes Behave as Transient Mesenchymal Precursor Cells. J Bone Miner Res. 2019;34:1387-1392 pubmed publisher

Wang G, Xie H, Wang L, Luo W, Wang Y, Jiang J, et al. Switching From Fear to No Fear by Different Neural Ensembles in Mouse Retrosplenial Cortex. Cereb Cortex. 2019;29:5085-5097 pubmed publisher

Dey A, Yang W, Gegonne A, Nishiyama A, Pan R, Yagi R, et al. BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses. EMBO J. 2019;38: pubmed publisher

Hass D, Barnstable C. Mitochondrial Uncoupling Protein 2 Knock-out Promotes Mitophagy to Decrease Retinal Ganglion Cell Death in a Mouse Model of Glaucoma. J Neurosci. 2019;39:3582-3596 pubmed publisher

Bossart E, Tasdemir N, Sikora M, Bahreini A, Levine K, Chen J, et al. SNAIL is induced by tamoxifen and leads to growth inhibition in invasive lobular breast carcinoma. Breast Cancer Res Treat. 2019;175:327-337 pubmed publisher

Wang Y, Xiong H, Liu D, Hill C, Ertay A, Li J, et al. Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells. Autophagy. 2019;15:886-899 pubmed publisher

DeNardo L, Liu C, Allen W, Adams E, Friedmann D, Fu L, et al. Temporal evolution of cortical ensembles promoting remote memory retrieval. Nat Neurosci. 2019;22:460-469 pubmed publisher

Liddiard K, Ruis B, Kan Y, Cleal K, Ashelford K, Hendrickson E, et al. DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase. Nucleic Acids Res. 2019;47:2402-2424 pubmed publisher

Toyama B, Arrojo e Drigo R, Lev Ram V, Ramachandra R, Deerinck T, Lechene C, et al. Visualization of long-lived proteins reveals age mosaicism within nuclei of postmitotic cells. J Cell Biol. 2019;218:433-444 pubmed publisher

Liuyu T, Yu K, Ye L, Zhang Z, Zhang M, Ren Y, et al. Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS. Cell Res. 2019;29:67-79 pubmed publisher

Kamerkar S, Kraus F, Sharpe A, Pucadyil T, Ryan M. Dynamin-related protein 1 has membrane constricting and severing abilities sufficient for mitochondrial and peroxisomal fission. Nat Commun. 2018;9:5239 pubmed publisher

Medina Cano D, Ucuncu E, Nguyen L, Nicouleau M, Lipecka J, Bizot J, et al. High N-glycan multiplicity is critical for neuronal adhesion and sensitizes the developing cerebellum to N-glycosylation defect. elife. 2018;7: pubmed publisher

Stone O, El Brolosy M, Wilhelm K, Liu X, Romão A, Grillo E, et al. Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells. Nat Commun. 2018;9:4077 pubmed publisher

Chowdhury A, Caroni P. Time units for learning involving maintenance of system-wide cFos expression in neuronal assemblies. Nat Commun. 2018;9:4122 pubmed publisher

Verma M, Asakura Y, Murakonda B, Pengo T, Latroche C, Chazaud B, et al. Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling. Cell Stem Cell. 2018;23:530-543.e9 pubmed publisher

van Lidth de Jeude J, Spaan C, Meijer B, Smit W, Soeratram T, Wielenga M, et al. Heterozygosity of Chaperone Grp78 Reduces Intestinal Stem Cell Regeneration Potential and Protects against Adenoma Formation. Cancer Res. 2018;78:6098-6106 pubmed publisher

Rademacher B, Meske L, Matkowskyj K, Hanlon B, Carchman E. Genetic inhibition of autophagy in a transgenic mouse model of anal cancer. J Carcinog. 2018;17:3 pubmed publisher

Jørgensen M, de Lichtenberg K, Collin C, Klinck R, Ekberg J, Engelstoft M, et al. Neurog3-dependent pancreas dysgenesis causes ectopic pancreas in Hes1 mutant mice. Development. 2018;145: pubmed publisher

Zhang T, Wang Q, Fredimoses M, Gao G, Wang K, Chen H, et al. The Ashitaba (Angelica keiskei) Chalcones 4-hydroxyderricin and Xanthoangelol Suppress Melanomagenesis By Targeting BRAF and PI3K. Cancer Prev Res (Phila). 2018;11:607-620 pubmed publisher

Su T, Stanley G, Sinha R, D Amato G, Das S, Rhee S, et al. Single-cell analysis of early progenitor cells that build coronary arteries. Nature. 2018;559:356-362 pubmed publisher

Sustarsic E, Ma T, Lynes M, Larsen M, Karavaeva I, Havelund J, et al. Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis. Cell Metab. 2018;28:159-174.e11 pubmed publisher

Canovas B, Igea A, Sartori A, Gomis R, Paull T, Isoda M, et al. Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells. Cancer Cell. 2018;33:1094-1110.e8 pubmed publisher

Baghdadi M, Castel D, Machado L, Fukada S, Birk D, Relaix F, et al. Reciprocal signalling by Notch-Collagen V-CALCR retains muscle stem cells in their niche. Nature. 2018;557:714-718 pubmed publisher

Pichol Thievend C, Betterman K, Liu X, Ma W, Skoczylas R, Lesieur E, et al. A blood capillary plexus-derived population of progenitor cells contributes to genesis of the dermal lymphatic vasculature during embryonic development. Development. 2018;145: pubmed publisher

Oldrini B, Curiel García A, Marques C, Matia V, Uluçkan O, Graña Castro O, et al. Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling. Nat Commun. 2018;9:1466 pubmed publisher

Gouveia L, Betsholtz C, Andrae J. PDGF-A signaling is required for secondary alveolar septation and controls epithelial proliferation in the developing lung. Development. 2018;145: pubmed publisher

Wong N, Wong W. Engineering a Dual Small Molecule Gated ZAP70 Switch in T Cells. ACS Synth Biol. 2018;7:969-977 pubmed publisher

Dresselhaus E, Boersma M, Meffert M. Targeting of NF-κB to Dendritic Spines Is Required for Synaptic Signaling and Spine Development. J Neurosci. 2018;38:4093-4103 pubmed publisher

Tasaka G, Guenthner C, Shalev A, Gilday O, Luo L, Mizrahi A. Genetic tagging of active neurons in auditory cortex reveals maternal plasticity of coding ultrasonic vocalizations. Nat Commun. 2018;9:871 pubmed publisher

Rhee S, Chung J, King D, D Amato G, Paik D, Duan A, et al. Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease. Nat Commun. 2018;9:368 pubmed publisher

Ding L, Zhang Y, Han L, Fu L, Mei X, Wang J, et al. Activating and sustaining c-Myc by depletion of miR-144/451 gene locus contributes to B-lymphomagenesis. Oncogene. 2018;37:1293-1307 pubmed publisher

Yui S, Azzolin L, Maimets M, Pedersen M, Fordham R, Hansen S, et al. YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration. Cell Stem Cell. 2018;22:35-49.e7 pubmed publisher

Chang C, Kuo C, Ito T, Su Y, Jiang S, Chiu M, et al. CK1? ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation. Proc Natl Acad Sci U S A. 2017;114:E8035-E8044 pubmed publisher

Chen X, Clark J, Wunderlich M, Fan C, Davis A, Chen S, et al. Autophagy is dispensable for Kmt2a/Mll-Mllt3/Af9 AML maintenance and anti-leukemic effect of chloroquine. Autophagy. 2017;13:955-966 pubmed publisher

Alsharif F, Dave K, Samy A, Saleh K, Amin M, Perumal O. Influence of Hydroalcoholic Vehicle on In Vitro Transport of 4-Hydroxy Tamoxifen Through the Mammary Papilla (Nipple). AAPS PharmSciTech. 2017;18:1366-1373 pubmed publisher

Fagnocchi L, Cherubini A, Hatsuda H, Fasciani A, Mazzoleni S, Poli V, et al. A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity. Nat Commun. 2016;7:11903 pubmed publisher

Kroon P, Gadiot J, Peeters M, Gasparini A, Deken M, Yagita H, et al. Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma. Cancer Immunol Immunother. 2016;65:753-63 pubmed publisher

Li Z, Hodgkinson T, Gothard E, Boroumand S, Lamb R, Cummins I, et al. Epidermal Notch1 recruits RORγ(+) group 3 innate lymphoid cells to orchestrate normal skin repair. Nat Commun. 2016;7:11394 pubmed publisher

Yeo S, Itahana Y, Guo A, Han R, Iwamoto K, Nguyen H, et al. Transglutaminase 2 contributes to a TP53-induced autophagy program to prevent oncogenic transformation. elife. 2016;5:e07101 pubmed publisher

Han H, Chen Y, Cheng L, Prochownik E, Li Y. microRNA-206 impairs c-Myc-driven cancer in a synthetic lethal manner by directly inhibiting MAP3K13. Oncotarget. 2016;7:16409-19 pubmed publisher

Ray J, Mirata F, Pérollier C, Arotcarena M, Bayoudh S, Resmini M. Smart coumarin-tagged imprinted polymers for the rapid detection of tamoxifen. Anal Bioanal Chem. 2016;408:1855-61 pubmed publisher

D Amato G, Luxán G, del Monte Nieto G, Martínez Poveda B, Torroja C, Walter W, et al. Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016;18:7-20 pubmed publisher

Hussien Y, Podojil J, Robinson A, Lee A, Miller S, Popko B. ER Chaperone BiP/GRP78 Is Required for Myelinating Cell Survival and Provides Protection during Experimental Autoimmune Encephalomyelitis. J Neurosci. 2015;35:15921-33 pubmed publisher

Uematsu T, Iizasa E, Kobayashi N, Yoshida H, Hara H. Loss of CARD9-mediated innate activation attenuates severe influenza pneumonia without compromising host viral immunity. Sci Rep. 2015;5:17577 pubmed publisher

Vitre B, Holland A, Kulukian A, Shoshani O, Hirai M, Wang Y, et al. Chronic centrosome amplification without tumorigenesis. Proc Natl Acad Sci U S A. 2015;112:E6321-30 pubmed publisher

Tan P, Guan H, Xie L, Mi B, Fang Z, Li J, et al. FOXO1 inhibits osteoclastogenesis partially by antagnozing MYC. Sci Rep. 2015;5:16835 pubmed publisher

Lee O, Ivancic D, Allu S, Shidfar A, Kenney K, Helenowski I, et al. Local transdermal therapy to the breast for breast cancer prevention and DCIS therapy: preclinical and clinical evaluation. Cancer Chemother Pharmacol. 2015;76:1235-46 pubmed publisher

Liu T, Yu H, Ding L, Wu Z, Gonzalez De Los Santos F, Liu J, et al. Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis. PLoS ONE. 2015;10:e0142547 pubmed publisher

Raju K, Taneja I, Valicherla G, Challagundla M, Rashid M, Syed A, et al. No effect on pharmacokinetics of tamoxifen and 4-hydroxytamoxifen by multiple doses of red clover capsule in rats. Sci Rep. 2015;5:16126 pubmed publisher

Le Roux I, Konge J, Le Cam L, Flamant P, Tajbakhsh S. Numb is required to prevent p53-dependent senescence following skeletal muscle injury. Nat Commun. 2015;6:8528 pubmed publisher

Wu X, Bekker Jensen I, Christensen J, Rasmussen K, Sidoli S, Qi Y, et al. Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals. Cell Res. 2015;25:1205-18 pubmed publisher

Nurmi H, Saharinen P, Zarkada G, Zheng W, Robciuc M, Alitalo K. VEGF-C is required for intestinal lymphatic vessel maintenance and lipid absorption. EMBO Mol Med. 2015;7:1418-25 pubmed publisher

Le Gal K, Ibrahim M, Wiel C, Sayin V, Akula M, Karlsson C, et al. Antioxidants can increase melanoma metastasis in mice. Sci Transl Med. 2015;7:308re8 pubmed publisher

Jacome A, Gutierrez Martinez P, Schiavoni F, Tenaglia E, Martinez P, Rodríguez Acebes S, et al. NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity. EMBO J. 2015;34:2604-19 pubmed publisher

Amin D, Ahuja D, Yaswen P, Moasser M. A TORC2-Akt Feed-Forward Topology Underlies HER3 Resiliency in HER2-Amplified Cancers. Mol Cancer Ther. 2015;14:2805-17 pubmed publisher

Clocchiatti A, Di Giorgio E, Viviani G, Streuli C, Sgorbissa A, Picco R, et al. The MEF2-HDAC axis controls proliferation of mammary epithelial cells and acini formation in vitro. J Cell Sci. 2015;128:3961-76 pubmed publisher

Dolatshad H, Biggs D, Diaz R, Hortin N, Preece C, Davies B. A versatile transgenic allele for mouse overexpression studies. Mamm Genome. 2015;26:598-608 pubmed publisher

Xue X, Yang Y, Zhang A, Fong K, Kim J, Song B, et al. LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer. Oncogene. 2016;35:2746-55 pubmed publisher

Ghaye A, Bergemann D, Tarifeño Saldivia E, Flasse L, Von Berg V, Peers B, et al. Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration. BMC Biol. 2015;13:70 pubmed publisher

Mosimann C, Panáková D, Werdich A, Musso G, Burger A, Lawson K, et al. Chamber identity programs drive early functional partitioning of the heart. Nat Commun. 2015;6:8146 pubmed publisher

Ledee D, Smith L, Bruce M, Kajimoto M, Isern N, Portman M, et al. c-Myc Alters Substrate Utilization and O-GlcNAc Protein Posttranslational Modifications without Altering Cardiac Function during Early Aortic Constriction. PLoS ONE. 2015;10:e0135262 pubmed publisher

Gazy I, Zeevi D, Renbaum P, Zeligson S, Eini L, Bashari D, et al. TODRA, a lncRNA at the RAD51 Locus, Is Oppositely Regulated to RAD51, and Enhances RAD51-Dependent DSB (Double Strand Break) Repair. PLoS ONE. 2015;10:e0134120 pubmed publisher

Serra H, Chivite I, Angulo Urarte A, Soler A, Sutherland J, Arruabarrena Aristorena A, et al. PTEN mediates Notch-dependent stalk cell arrest in angiogenesis. Nat Commun. 2015;6:7935 pubmed publisher

Chesney J, Clark J, Lanceta L, Trent J, Telang S. Targeting the sugar metabolism of tumors with a first-in-class 6-phosphofructo-2-kinase (PFKFB4) inhibitor. Oncotarget. 2015;6:18001-11 pubmed

Wang H, Tao L, Qi K, Zhang H, Feng D, Wei W, et al. Quercetin reverses tamoxifen resistance in breast cancer cells. J BUON. 2015;20:707-13 pubmed

Karthik G, Ma R, Lövrot J, Kis L, Lindh C, Blomquist L, et al. mTOR inhibitors counteract tamoxifen-induced activation of breast cancer stem cells. Cancer Lett. 2015;367:76-87 pubmed publisher

Lizama C, Hawkins J, Schmitt C, Bos F, Zape J, Cautivo K, et al. Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition. Nat Commun. 2015;6:7739 pubmed publisher

Kim S, Lee J, Oh S, Nam S, Lee J. Differential effect of EGFR inhibitors on tamoxifen-resistant breast cancer cells. Oncol Rep. 2015;34:1613-9 pubmed publisher

Hong S, Wu P, Karkhanis M, Park J. ERK1/2 can feedback-regulate cellular MEK1/2 levels. Cell Signal. 2015;27:1939-48 pubmed publisher

Wardell S, Nelson E, Chao C, Alley H, McDonnell D. Evaluation of the pharmacological activities of RAD1901, a selective estrogen receptor degrader. Endocr Relat Cancer. 2015;22:713-24 pubmed publisher

Liu Z, Miao T, Feng T, Jiang Z, Li M, Zhou L, et al. miR-451a Inhibited Cell Proliferation and Enhanced Tamoxifen Sensitive in Breast Cancer via Macrophage Migration Inhibitory Factor. Biomed Res Int. 2015;2015:207684 pubmed publisher

Chen S, Hsieh J, Huang R, Sakamuru S, Hsin L, Xia M, et al. Cell-Based High-Throughput Screening for Aromatase Inhibitors in the Tox21 10K Library. Toxicol Sci. 2015;147:446-57 pubmed publisher

Drooger J, Jager A, Lam M, den Boer M, Sleijfer S, Mathijssen R, et al. Development and validation of an UPLC-MS/MS method for the quantification of tamoxifen and its main metabolites in human scalp hair. J Pharm Biomed Anal. 2015;114:416-25 pubmed publisher

Huang J, Urtatiz O, Van Raamsdonk C. Oncogenic G Protein GNAQ Induces Uveal Melanoma and Intravasation in Mice. Cancer Res. 2015;75:3384-97 pubmed publisher

Liu Y, Miao Q, Yuan J, Han S, Zhang P, Li S, et al. Ascl1 Converts Dorsal Midbrain Astrocytes into Functional Neurons In Vivo. J Neurosci. 2015;35:9336-55 pubmed publisher

Koike M, Nojiri H, Ozawa Y, Watanabe K, Muramatsu Y, Kaneko H, et al. Mechanical overloading causes mitochondrial superoxide and SOD2 imbalance in chondrocytes resulting in cartilage degeneration. Sci Rep. 2015;5:11722 pubmed publisher

Arif K, Hussain I, Rea C, El Sheemy M. The role of Nanog expression in tamoxifen-resistant breast cancer cells. Onco Targets Ther. 2015;8:1327-34 pubmed publisher

Mitschka S, Ulas T, Goller T, Schneider K, Egert A, Mertens J, et al. Co-existence of intact stemness and priming of neural differentiation programs in mES cells lacking Trim71. Sci Rep. 2015;5:11126 pubmed publisher

Cuevas M, Gaska J, Gist A, King J, Sheller R, Todd M. Estrogen-dependent expression and subcellular localization of the tight junction protein claudin-4 in HEC-1A endometrial cancer cells. Int J Oncol. 2015;47:650-6 pubmed publisher

Yousefi S, Morshed M, Amini P, Stojkov D, Simon D, von Gunten S, et al. Basophils exhibit antibacterial activity through extracellular trap formation. Allergy. 2015;70:1184-8 pubmed publisher

Jiang X, Nevins J, Shats I, Chi J. E2F1-Mediated Induction of NFYB Attenuates Apoptosis via Joint Regulation of a Pro-Survival Transcriptional Program. PLoS ONE. 2015;10:e0127951 pubmed publisher

Pällmann N, Braig M, Sievert H, Preukschas M, Hermans Borgmeyer I, Schweizer M, et al. Biological Relevance and Therapeutic Potential of the Hypusine Modification System. J Biol Chem. 2015;290:18343-60 pubmed publisher

Huang Y, Hamana T, Liu J, Wang C, An L, You P, et al. Prostate Sphere-forming Stem Cells Are Derived from the P63-expressing Basal Compartment. J Biol Chem. 2015;290:17745-52 pubmed publisher

Tagore M, McAndrew M, Gjidoda A, Floer M. The Lineage-Specific Transcription Factor PU.1 Prevents Polycomb-Mediated Heterochromatin Formation at Macrophage-Specific Genes. Mol Cell Biol. 2015;35:2610-25 pubmed publisher

Shai A, Dankort D, Juan J, Green S, McMahon M. TP53 Silencing Bypasses Growth Arrest of BRAFV600E-Induced Lung Tumor Cells in a Two-Switch Model of Lung Tumorigenesis. Cancer Res. 2015;75:3167-80 pubmed publisher

Lee J, Hur H, Yun H, Kim Y, Yang S, Kim S, et al. HOXB5 Promotes the Proliferation and Invasion of Breast Cancer Cells. Int J Biol Sci. 2015;11:701-11 pubmed publisher

Kloet D, Polderman P, Eijkelenboom A, Smits L, van Triest M, van den Berg M, et al. FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21(Cip1/Waf1). Biochem J. 2015;469:289-98 pubmed publisher

Fujita Sato S, Galeas J, Truitt M, Pitt C, Urisman A, Bandyopadhyay S, et al. Enhanced MET Translation and Signaling Sustains K-Ras-Driven Proliferation under Anchorage-Independent Growth Conditions. Cancer Res. 2015;75:2851-62 pubmed publisher

Zhang M, Qiu Q, Li Z, Sachdeva M, Min H, Cardona D, et al. HIF-1 Alpha Regulates the Response of Primary Sarcomas to Radiation Therapy through a Cell Autonomous Mechanism. Radiat Res. 2015;183:594-609 pubmed

Zhang Y, Chen G, Liu Z, Tian S, Zhang J, Carey C, et al. Genetic vaccines to potentiate the effective CD103+ dendritic cell-mediated cross-priming of antitumor immunity. J Immunol. 2015;194:5937-47 pubmed publisher

Zhang M, Zhu X, Zhang Y, Cai Y, Chen J, Sivaprakasam S, et al. RCAD/Ufl1, a Ufm1 E3 ligase, is essential for hematopoietic stem cell function and murine hematopoiesis. Cell Death Differ. 2015;22:1922-34 pubmed publisher

Zhang Y, Tian S, Liu Z, Zhang J, Zhang M, Bosenberg M, et al. Dendritic cell-derived interleukin-15 is crucial for therapeutic cancer vaccine potency. Oncoimmunology. 2014;3:e959321 pubmed

Goldstein M, Kastan M. Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding. Cancer Res. 2015;75:2699-707 pubmed publisher

Bonsignore L, Butler J, Klinge C, Schaner Tooley C. Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesis. Oncotarget. 2015;6:12248-63 pubmed

Montes M, Nielsen M, Maglieri G, Jacobsen A, Højfeldt J, Agrawal Singh S, et al. The lncRNA MIR31HG regulates p16(INK4A) expression to modulate senescence. Nat Commun. 2015;6:6967 pubmed publisher

Baral A, Irani N, Fujimoto M, Nakano A, Mayor S, Mathew M. Salt-induced remodeling of spatially restricted clathrin-independent endocytic pathways in Arabidopsis root. Plant Cell. 2015;27:1297-315 pubmed publisher

McFarlane M, Cantoria M, Linden A, January B, Liang G, Engelking L. Scap is required for sterol synthesis and crypt growth in intestinal mucosa. J Lipid Res. 2015;56:1560-71 pubmed publisher

Chang B, Tessneer K, McManus J, Liu X, Hahn S, Pasula S, et al. Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development. Nat Commun. 2015;6:6380 pubmed publisher

Bianchi R, Teijeira A, Proulx S, Christiansen A, Seidel C, Rülicke T, et al. A transgenic Prox1-Cre-tdTomato reporter mouse for lymphatic vessel research. PLoS ONE. 2015;10:e0122976 pubmed publisher

Raha P, Thomas S, Thurn K, Park J, Munster P. Combined histone deacetylase inhibition and tamoxifen induces apoptosis in tamoxifen-resistant breast cancer models, by reversing Bcl-2 overexpression. Breast Cancer Res. 2015;17:26 pubmed publisher

Piasecka Srader J, Blanco F, Delman D, Dixon D, Geiser J, Ciereszko R, et al. Tamoxifen prevents apoptosis and follicle loss from cyclophosphamide in cultured rat ovaries. Biol Reprod. 2015;92:132 pubmed publisher

Otsuka K, Iwasaki T. Effects of dose rates on radiation-induced replenishment of intestinal stem cells determined by Lgr5 lineage tracing. J Radiat Res. 2015;56:615-22 pubmed publisher

Li Y, Qi X, Liu B, Huang H. The STAT5-GATA2 pathway is critical in basophil and mast cell differentiation and maintenance. J Immunol. 2015;194:4328-38 pubmed publisher

Tan J, Sirey T, Honti F, Graham B, Piovesan A, Merkenschlager M, et al. Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells. Genome Res. 2015;25:655-66 pubmed publisher

Kim Y, Larsen H, Rué P, Lemaire L, Ferrer J, Grapin Botton A. Cell cycle-dependent differentiation dynamics balances growth and endocrine differentiation in the pancreas. PLoS Biol. 2015;13:e1002111 pubmed publisher

Schnell S, Ambesi Impiombato A, Sanchez Martin M, Belver L, Xu L, Qin Y, et al. Therapeutic targeting of HES1 transcriptional programs in T-ALL. Blood. 2015;125:2806-14 pubmed publisher

You L, Yan K, Zou J, Zhao H, Bertos N, Park M, et al. The chromatin regulator Brpf1 regulates embryo development and cell proliferation. J Biol Chem. 2015;290:11349-64 pubmed publisher

Li T, Shi Y, Wang P, Guachalla L, Sun B, Joerss T, et al. Smg6/Est1 licenses embryonic stem cell differentiation via nonsense-mediated mRNA decay. EMBO J. 2015;34:1630-47 pubmed publisher

Moding E, Castle K, Perez B, Oh P, Min H, Norris H, et al. Tumor cells, but not endothelial cells, mediate eradication of primary sarcomas by stereotactic body radiation therapy. Sci Transl Med. 2015;7:278ra34 pubmed publisher

Yeung A, Hale C, Xia J, Tate P, Goulding D, Keane J, et al. Conditional-ready mouse embryonic stem cell derived macrophages enable the study of essential genes in macrophage function. Sci Rep. 2015;5:8908 pubmed publisher

Carr T, Feehan R, Hall M, Rüegg M, Shantz L. Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors. Carcinogenesis. 2015;36:487-97 pubmed publisher

Flament H, Alonso Ramirez R, Prémel V, Joncker N, Jacquet A, Scholl S, et al. Modeling the specific CD4+ T cell response against a tumor neoantigen. J Immunol. 2015;194:3501-12 pubmed publisher

Kwong L, Boland G, Frederick D, Helms T, Akid A, Miller J, et al. Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma. J Clin Invest. 2015;125:1459-70 pubmed publisher

Jo A, Yun H, Kim J, Lim S, Choi H, Kang B, et al. Prolyl isomerase PIN1 negatively regulates SGK1 stability to mediate tamoxifen resistance in breast cancer cells. Anticancer Res. 2015;35:785-94 pubmed

Martin T, Plautz S, Pannier A. Temporal endogenous gene expression profiles in response to polymer-mediated transfection and profile comparison to lipid-mediated transfection. J Gene Med. 2015;17:33-53 pubmed publisher

Blij S, Parenti A, Tabatabai Yazdi N, Ralston A. Cdx2 efficiently induces trophoblast stem-like cells in naïve, but not primed, pluripotent stem cells. Stem Cells Dev. 2015;24:1352-65 pubmed publisher

Perna D, Karreth F, Rust A, Perez Mancera P, Rashid M, Iorio F, et al. BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model. Proc Natl Acad Sci U S A. 2015;112:E536-45 pubmed publisher

Kumar R, Bach M, Mainoldi F, Maruya M, Kishigami S, Jumaa H, et al. Antibody repertoire diversification through VH gene replacement in mice cloned from an IgA plasma cell. Proc Natl Acad Sci U S A. 2015;112:E450-7 pubmed publisher

Barcus C, Holt E, Keely P, Eliceiri K, Schuler L. Dense collagen-I matrices enhance pro-tumorigenic estrogen-prolactin crosstalk in MCF-7 and T47D breast cancer cells. PLoS ONE. 2015;10:e0116891 pubmed publisher

Wu Q, Fukuda K, Weinstein M, Graff J, Saga Y. SMAD2 and p38 signaling pathways act in concert to determine XY primordial germ cell fate in mice. Development. 2015;142:575-86 pubmed publisher

Zarkada G, Heinolainen K, Makinen T, Kubota Y, Alitalo K. VEGFR3 does not sustain retinal angiogenesis without VEGFR2. Proc Natl Acad Sci U S A. 2015;112:761-6 pubmed publisher

He W, Liu R, Yang S, Yuan F. Chemotherapeutic effect of tamoxifen on temozolomide-resistant gliomas. Anticancer Drugs. 2015;26:293-300 pubmed publisher

Gu Y, Bouwman P, Greco D, Saarela J, Yadav B, Jonkers J, et al. Suppression of BRCA1 sensitizes cells to proteasome inhibitors. Cell Death Dis. 2014;5:e1580 pubmed publisher

Li Z, Yu J, Hosohama L, Nee K, Gkountela S, Chaudhari S, et al. The Sm protein methyltransferase PRMT5 is not required for primordial germ cell specification in mice. EMBO J. 2015;34:748-58 pubmed publisher

Washkowitz A, Schall C, Zhang K, Wurst W, Floss T, Mager J, et al. Mga is essential for the survival of pluripotent cells during peri-implantation development. Development. 2015;142:31-40 pubmed publisher

Trembley M, Velasquez L, de Mesy Bentley K, Small E. Myocardin-related transcription factors control the motility of epicardium-derived cells and the maturation of coronary vessels. Development. 2015;142:21-30 pubmed publisher

Henriksson S, Rassoolzadeh H, Hedström E, Coucoravas C, Julner A, Goldstein M, et al. The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair. Genes Dev. 2014;28:2726-38 pubmed publisher

Wagner K, Cherfils Vicini J, Hosen N, Hohenstein P, Gilson E, Hastie N, et al. The Wilms' tumour suppressor Wt1 is a major regulator of tumour angiogenesis and progression. Nat Commun. 2014;5:5852 pubmed publisher

Salvatierra J, Lee D, Zibetti C, Duran Moreno M, Yoo S, Newman E, et al. The LIM homeodomain factor Lhx2 is required for hypothalamic tanycyte specification and differentiation. J Neurosci. 2014;34:16809-20 pubmed publisher

Xu C, Hasan S, Schmidt I, Rocha S, Pitulescu M, Bussmann J, et al. Arteries are formed by vein-derived endothelial tip cells. Nat Commun. 2014;5:5758 pubmed publisher

Simmini S, Bialecka M, Huch M, Kester L, van de Wetering M, Sato T, et al. Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2. Nat Commun. 2014;5:5728 pubmed publisher

Stanisavljevic J, Loubat Casanovas J, Herrera M, Luque T, Peña R, Lluch A, et al. Snail1-expressing fibroblasts in the tumor microenvironment display mechanical properties that support metastasis. Cancer Res. 2015;75:284-95 pubmed publisher

Antunes M, Raymundo S, de Oliveira V, Staudt D, Gössling G, Peteffi G, et al. Ultra-high performance liquid chromatography tandem mass spectrometric method for the determination of tamoxifen, N-desmethyltamoxifen, 4-hydroxytamoxifen and endoxifen in dried blood spots--development, validation and clinical application during bre. Talanta. 2015;132:775-84 pubmed publisher

Zhao B, Wu Z, Grillet N, Yan L, Xiong W, Harkins Perry S, et al. TMIE is an essential component of the mechanotransduction machinery of cochlear hair cells. Neuron. 2014;84:954-67 pubmed publisher

Ishii A, Furusho M, Dupree J, Bansal R. Role of ERK1/2 MAPK signaling in the maintenance of myelin and axonal integrity in the adult CNS. J Neurosci. 2014;34:16031-45 pubmed publisher

Luciani Torres M, Moore D, Goodson W, Dairkee S. Exposure to the polyester PET precursor--terephthalic acid induces and perpetuates DNA damage-harboring non-malignant human breast cells. Carcinogenesis. 2015;36:168-76 pubmed publisher

Alao J, Michlikova S, Dinér P, Grøtli M, Sunnerhagen P. Selective inhibition of RET mediated cell proliferation in vitro by the kinase inhibitor SPP86. BMC Cancer. 2014;14:853 pubmed publisher

WANG Y, McAllister F, Bailey J, Scott S, Hendley A, Leach S, et al. Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia. PLoS ONE. 2014;9:e113127 pubmed publisher

Lenz A, Toren Haritan G, Efrat S. Redifferentiation of adult human β cells expanded in vitro by inhibition of the WNT pathway. PLoS ONE. 2014;9:e112914 pubmed publisher

Willer A, Jakobsen J, Ohlsson E, Rapin N, Waage J, Billing M, et al. TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia. Leukemia. 2015;29:1018-31 pubmed publisher

Kockx M, Karunakaran D, Traini M, Xue J, Huang K, Nawara D, et al. Pharmacological inhibition of dynamin II reduces constitutive protein secretion from primary human macrophages. PLoS ONE. 2014;9:e111186 pubmed publisher

Gehrke N, Garcia Bardon D, Mann A, Schad A, Alt Y, Wörns M, et al. Acute organ failure following the loss of anti-apoptotic cellular FLICE-inhibitory protein involves activation of innate immune receptors. Cell Death Differ. 2015;22:826-37 pubmed publisher

DiTommaso T, Cottle D, Pearson H, Schlüter H, Kaur P, Humbert P, et al. Keratin 76 is required for tight junction function and maintenance of the skin barrier. PLoS Genet. 2014;10:e1004706 pubmed publisher

Rožman S, Yousefi S, Oberson K, Kaufmann T, Benarafa C, Simon H. The generation of neutrophils in the bone marrow is controlled by autophagy. Cell Death Differ. 2015;22:445-56 pubmed publisher

Tam E, Nguyen T, Lim C, Lee P, Li Z, Jiang X, et al. 3-Deazaneplanocin A and neplanocin A analogues and their effects on apoptotic cell death. ChemMedChem. 2015;10:173-82 pubmed publisher

Reid J, Goetz M, Buhrow S, Walden C, Safgren S, Kuffel M, et al. Pharmacokinetics of endoxifen and tamoxifen in female mice: implications for comparative in vivo activity studies. Cancer Chemother Pharmacol. 2014;74:1271-8 pubmed publisher

Sweeney E, Fan P, Jordan V. Molecular modulation of estrogen-induced apoptosis by synthetic progestins in hormone replacement therapy: an insight into the women's health initiative study. Cancer Res. 2014;74:7060-8 pubmed publisher

Germann M, Xu H, Malaterre J, Sampurno S, Huyghe M, Cheasley D, et al. Tripartite interactions between Wnt signaling, Notch and Myb for stem/progenitor cell functions during intestinal tumorigenesis. Stem Cell Res. 2014;13:355-66 pubmed publisher

Redmond A, Byrne C, Bane F, Brown G, Tibbitts P, O brien K, et al. Genomic interaction between ER and HMGB2 identifies DDX18 as a novel driver of endocrine resistance in breast cancer cells. Oncogene. 2015;34:3871-80 pubmed publisher

Radde B, Ivanova M, Mai H, Salabei J, Hill B, Klinge C. Bioenergetic differences between MCF-7 and T47D breast cancer cells and their regulation by oestradiol and tamoxifen. Biochem J. 2015;465:49-61 pubmed publisher

Vizioli M, Santos J, Pilotti S, Mazzoni M, Anania M, Miranda C, et al. Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved. Oncotarget. 2014;5:8270-83 pubmed

Overton K, Spencer S, Noderer W, Meyer T, Wang C. Basal p21 controls population heterogeneity in cycling and quiescent cell cycle states. Proc Natl Acad Sci U S A. 2014;111:E4386-93 pubmed publisher

Vitaliano Prunier A, Halftermeyer J, Ablain J, de Reynies A, Peres L, Le Bras M, et al. Clearance of PML/RARA-bound promoters suffice to initiate APL differentiation. Blood. 2014;124:3772-80 pubmed publisher

Steger J, Füller E, Garcia Cuellar M, Hetzner K, Slany R. Insulin-like growth factor 1 is a direct HOXA9 target important for hematopoietic transformation. Leukemia. 2015;29:901-8 pubmed publisher

Chang Q, Tang W, Kim Y, Lin X. Timed conditional null of connexin26 in mice reveals temporary requirements of connexin26 in key cochlear developmental events before the onset of hearing. Neurobiol Dis. 2015;73:418-27 pubmed publisher

Fan P, Cunliffe H, Griffith O, Agboke F, Ramos P, Gray J, et al. Identification of gene regulation patterns underlying both oestrogen- and tamoxifen-stimulated cell growth through global gene expression profiling in breast cancer cells. Eur J Cancer. 2014;50:2877-86 pubmed publisher

Wang W, Kissig M, Rajakumari S, Huang L, Lim H, Won K, et al. Ebf2 is a selective marker of brown and beige adipogenic precursor cells. Proc Natl Acad Sci U S A. 2014;111:14466-71 pubmed publisher

Koike H, Ouchi R, Ueno Y, Nakata S, Obana Y, Sekine K, et al. Polycomb group protein Ezh2 regulates hepatic progenitor cell proliferation and differentiation in murine embryonic liver. PLoS ONE. 2014;9:e104776 pubmed publisher

Morel L, Higashimori H, Tolman M, Yang Y. VGluT1+ neuronal glutamatergic signaling regulates postnatal developmental maturation of cortical protoplasmic astroglia. J Neurosci. 2014;34:10950-62 pubmed publisher

Chesney J, Clark J, KLARER A, Imbert Fernandez Y, Lane A, Telang S. Fructose-2,6-bisphosphate synthesis by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth. Oncotarget. 2014;5:6670-86 pubmed

Pinto C, Grimaldi M, Boulahtouf A, Pakdel F, Brion F, Aït Aïssa S, et al. Selectivity of natural, synthetic and environmental estrogens for zebrafish estrogen receptors. Toxicol Appl Pharmacol. 2014;280:60-9 pubmed publisher

Zhang T, Cronshaw J, Kanu N, Snijders A, Behrens A. UBR5-mediated ubiquitination of ATMIN is required for ionizing radiation-induced ATM signaling and function. Proc Natl Acad Sci U S A. 2014;111:12091-6 pubmed publisher

Chiu Y, Lin I, Su S, Wang K, Yang S, Tsai D, et al. Transcription factor ABF-1 suppresses plasma cell differentiation but facilitates memory B cell formation. J Immunol. 2014;193:2207-17 pubmed publisher

Duan L, Danzer B, Levenson V, Maki C. Critical roles for nitric oxide and ERK in the completion of prosurvival autophagy in 4OHTAM-treated estrogen receptor-positive breast cancer cells. Cancer Lett. 2014;353:290-300 pubmed publisher

Ito T, Yokoyama M, Yoshida Y, Nojima A, Kassai H, Oishi K, et al. A crucial role for CDC42 in senescence-associated inflammation and atherosclerosis. PLoS ONE. 2014;9:e102186 pubmed publisher

Ngo T, Barisone G, Lam K, Dίaz E. MXD3 regulation of DAOY cell proliferation dictated by time course of activation. BMC Cell Biol. 2014;15:30 pubmed publisher

Putluri N, Maity S, Kommagani R, Kommangani R, Creighton C, Putluri V, et al. Pathway-centric integrative analysis identifies RRM2 as a prognostic marker in breast cancer associated with poor survival and tamoxifen resistance. Neoplasia. 2014;16:390-402 pubmed publisher

Wei Y, Lai X, Yu S, Chen S, Ma Y, Zhang Y, et al. Exosomal miR-221/222 enhances tamoxifen resistance in recipient ER-positive breast cancer cells. Breast Cancer Res Treat. 2014;147:423-31 pubmed publisher

Smeets M, DeLuca E, Wall M, Quach J, Chalk A, Deans A, et al. The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis. J Clin Invest. 2014;124:3551-65 pubmed publisher

Liu X, Kwak D, Lu Z, Xu X, Fassett J, Wang H, et al. Endoplasmic reticulum stress sensor protein kinase R-like endoplasmic reticulum kinase (PERK) protects against pressure overload-induced heart failure and lung remodeling. Hypertension. 2014;64:738-44 pubmed publisher

Chen J, Fu R, Cui Y, Pan J, Li Y, Zhang X, et al. LIM-homeodomain transcription factor Isl-1 mediates kisspeptin's effect on insulin secretion in mice. Mol Endocrinol. 2014;28:1276-90 pubmed publisher

Montavon G, Jauquier N, Coulon A, Peuchmaur M, Flahaut M, Bourloud K, et al. Wild-type ALK and activating ALK-R1275Q and ALK-F1174L mutations upregulate Myc and initiate tumor formation in murine neural crest progenitor cells. Oncotarget. 2014;5:4452-66 pubmed

Sun L, Yamaguchi S, Hirano K, Ichisaka T, Kuroda T, Tada T. Nanog co-regulated by Nodal/Smad2 and Oct4 is required for pluripotency in developing mouse epiblast. Dev Biol. 2014;392:182-92 pubmed publisher

Shives K, Beatman E, Chamanian M, O Brien C, Hobson Peters J, Beckham J. West nile virus-induced activation of mammalian target of rapamycin complex 1 supports viral growth and viral protein expression. J Virol. 2014;88:9458-71 pubmed publisher

Huang O, Xie Z, Zhang W, Lou Y, Mao Y, Liu H, et al. A771726, an anti-inflammatory drug, exerts an anticancer effect and reverses tamoxifen resistance in endocrine-resistant breast cancer cells. Oncol Rep. 2014;32:627-34 pubmed publisher

DeFalco T, Bhattacharya I, Williams A, Sams D, Capel B. Yolk-sac-derived macrophages regulate fetal testis vascularization and morphogenesis. Proc Natl Acad Sci U S A. 2014;111:E2384-93 pubmed publisher

Wu X, Yang Z, Wang X, Zhang Y, Wan H, Song Y, et al. Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosis. Cell Death Differ. 2014;21:1709-20 pubmed publisher

Yeh W, Lin H, Wu H, Chen D. Combination treatment of tamoxifen with risperidone in breast cancer. PLoS ONE. 2014;9:e98805 pubmed publisher

Bowen M, Ayturk U, Kurek K, Yang W, Warman M. SHP2 regulates chondrocyte terminal differentiation, growth plate architecture and skeletal cell fates. PLoS Genet. 2014;10:e1004364 pubmed publisher

Liu Y, He Y, Jin A, Tikunov A, Zhou L, Tollini L, et al. Ribosomal protein-Mdm2-p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation. Proc Natl Acad Sci U S A. 2014;111:E2414-22 pubmed publisher

Itahana Y, Han R, Barbier S, Lei Z, Rozen S, Itahana K. The uric acid transporter SLC2A9 is a direct target gene of the tumor suppressor p53 contributing to antioxidant defense. Oncogene. 2015;34:1799-810 pubmed publisher

Sievert H, Pällmann N, Miller K, Hermans Borgmeyer I, Venz S, Sendoel A, et al. A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformation. Dis Model Mech. 2014;7:963-76 pubmed publisher

Maximov P, Fernandes D, McDaniel R, Myers C, Curpan R, Jordan V. Influence of the length and positioning of the antiestrogenic side chain of endoxifen and 4-hydroxytamoxifen on gene activation and growth of estrogen receptor positive cancer cells. J Med Chem. 2014;57:4569-83 pubmed publisher

Gopinathan L, Tan S, Padmakumar V, Coppola V, Tessarollo L, Kaldis P. Loss of Cdk2 and cyclin A2 impairs cell proliferation and tumorigenesis. Cancer Res. 2014;74:3870-9 pubmed publisher

Zhou Y, Liu X, Xu L, Hunter Z, Cao Y, Yang G, et al. Transcriptional repression of plasma cell differentiation is orchestrated by aberrant over-expression of the ETS factor SPIB in Waldenström macroglobulinaemia. Br J Haematol. 2014;166:677-89 pubmed publisher

Yang W, Lee Y, Jones A, Woolnough J, Zhou D, Dai Q, et al. The histone H2A deubiquitinase Usp16 regulates embryonic stem cell gene expression and lineage commitment. Nat Commun. 2014;5:3818 pubmed publisher

Hayes C, Shicora A, Keough M, Snook A, Burns M, Gilmour S. Polyamine-blocking therapy reverses immunosuppression in the tumor microenvironment. Cancer Immunol Res. 2014;2:274-85 pubmed publisher

Bourassa P, Thomas T, Tajmir Riahi H. Locating the binding sites of antitumor drug tamoxifen and its metabolites with DNA. J Pharm Biomed Anal. 2014;95:193-9 pubmed publisher

Wong P, Yeoh C, Ahmad A, Chelala C, Gillett C, Speirs V, et al. Identification of MAGEA antigens as causal players in the development of tamoxifen-resistant breast cancer. Oncogene. 2014;33:4579-88 pubmed publisher

Wilson C, Gamper I, Perfetto A, Auw J, Littlewood T, Evan G. The kinetics of ER fusion protein activation in vivo. Oncogene. 2014;33:4877-80 pubmed publisher

Shiue C, Nematollahi Mahani A, Wright A. Myc-induced anchorage of the rDNA IGS region to nucleolar matrix modulates growth-stimulated changes in higher-order rDNA architecture. Nucleic Acids Res. 2014;42:5505-17 pubmed publisher

Reynolds C, Roderick J, LaBelle J, Bird G, Mathieu R, Bodaar K, et al. Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia. Leukemia. 2014;28:1819-27 pubmed publisher

Kim K, Kim G, Kim J, Yun H, Lim S, Choi H. Interleukin-22 promotes epithelial cell transformation and breast tumorigenesis via MAP3K8 activation. Carcinogenesis. 2014;35:1352-61 pubmed publisher

Jordan N, Dutkowski C, Barrow D, Mottram H, Hutcheson I, Nicholson R, et al. Impact of dual mTORC1/2 mTOR kinase inhibitor AZD8055 on acquired endocrine resistance in breast cancer in vitro. Breast Cancer Res. 2014;16:R12 pubmed publisher

Heger K, Fierens K, Vahl J, Aszodi A, Peschke K, Schenten D, et al. A20-deficient mast cells exacerbate inflammatory responses in vivo. PLoS Biol. 2014;12:e1001762 pubmed publisher

Khaw S, Merino D, Anderson M, Glaser S, Bouillet P, Roberts A, et al. Both leukaemic and normal peripheral B lymphoid cells are highly sensitive to the selective pharmacological inhibition of prosurvival Bcl-2 with ABT-199. Leukemia. 2014;28:1207-15 pubmed publisher

Alique M, Civantos E, Sanchez Lopez E, Lavoz C, Rayego Mateos S, Rodrígues Díez R, et al. Integrin-linked kinase plays a key role in the regulation of angiotensin II-induced renal inflammation. Clin Sci (Lond). 2014;127:19-31 pubmed publisher

Hsu H, Liu C, Lin J, Hsu T, Su K, Hung S. Repair of naphthalene-induced acute tracheal injury by basal cells depends on β-catenin. J Thorac Cardiovasc Surg. 2014;148:322-32 pubmed publisher

Prather P, Francisdevaraj F, Dates C, Greer A, Bratton S, Ford B, et al. CB1 and CB2 receptors are novel molecular targets for Tamoxifen and 4OH-Tamoxifen. Biochem Biophys Res Commun. 2013;441:339-43 pubmed publisher

Olive V, SABIO E, Bennett M, De Jong C, Biton A, McGann J, et al. A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis. elife. 2013;2:e00822 pubmed publisher

Khattak S, Schuez M, Richter T, Knapp D, Haigo S, Sandoval Guzmán T, et al. Germline transgenic methods for tracking cells and testing gene function during regeneration in the axolotl. Stem Cell Reports. 2013;1:90-103 pubmed publisher

Drosten M, Lechuga C, Barbacid M. Ras signaling is essential for skin development. Oncogene. 2014;33:2857-65 pubmed publisher

Pitta C, Papageorgis P, Charalambous C, Constantinou A. Reversal of ER-? silencing by chromatin modifying agents overrides acquired tamoxifen resistance. Cancer Lett. 2013;337:167-76 pubmed publisher

Li M, Nilsen A, Shi Y, Fusser M, Ding Y, Fu Y, et al. ALKBH4-dependent demethylation of actin regulates actomyosin dynamics. Nat Commun. 2013;4:1832 pubmed publisher

Cottle D, Kretzschmar K, Schweiger P, Quist S, Gollnick H, Natsuga K, et al. c-MYC-induced sebaceous gland differentiation is controlled by an androgen receptor/p53 axis. Cell Rep. 2013;3:427-41 pubmed publisher

Hooijkaas A, Gadiot J, Morrow M, Stewart R, Schumacher T, Blank C. Selective BRAF inhibition decreases tumor-resident lymphocyte frequencies in a mouse model of human melanoma. Oncoimmunology. 2012;1:609-617 pubmed

Contrepois K, Thuret J, Courbeyrette R, Fenaille F, Mann C. Deacetylation of H4-K16Ac and heterochromatin assembly in senescence. Epigenetics Chromatin. 2012;5:15 pubmed publisher

Koutsopoulos O, Koch C, Tosch V, Böhm J, North K, Laporte J. Mild functional differences of dynamin 2 mutations associated to centronuclear myopathy and Charcot-Marie Tooth peripheral neuropathy. PLoS ONE. 2011;6:e27498 pubmed publisher

Yao L, Yan X, Dong H, Nelson D, Liu C, Li X. Expression of an IRF-3 fusion protein and mouse estrogen receptor, inhibits hepatitis C viral replication in RIG-I-deficient Huh 7.5 cells. Virol J. 2011;8:445 pubmed publisher

Boersma M, Dresselhaus E, De Biase L, Mihalas A, Bergles D, Meffert M. A requirement for nuclear factor-kappaB in developmental and plasticity-associated synaptogenesis. J Neurosci. 2011;31:5414-25 pubmed publisher

Winpenny E, Lebel Potter M, Fernandez M, Brill M, Gotz M, Guillemot F, et al. Sequential generation of olfactory bulb glutamatergic neurons by Neurog2-expressing precursor cells. Neural Dev. 2011;6:12 pubmed publisher

Ye X, Wang Y, Rattner A, Nathans J. Genetic mosaic analysis reveals a major role for frizzled 4 and frizzled 8 in controlling ureteric growth in the developing kidney. Development. 2011;138:1161-72 pubmed publisher

Jimenez Guri E, Udina F, Colas J, Sharpe J, Padron Barthe L, Torres M, et al. Clonal analysis in mice underlines the importance of rhombomeric boundaries in cell movement restriction during hindbrain segmentation. PLoS ONE. 2010;5:e10112 pubmed publisher

Tureckova J, Vojtechova M, Krausova M, Sloncova E, Korinek V. Focal adhesion kinase functions as an akt downstream target in migration of colorectal cancer cells. Transl Oncol. 2009;2:281-90 pubmed

Zimmermann M, Tilghman S, Boue S, Salvo V, Elliott S, Williams K, et al. Glyceollin I, a novel antiestrogenic phytoalexin isolated from activated soy. J Pharmacol Exp Ther. 2010;332:35-45 pubmed publisher

Chisamore M, Cunningham M, Flores O, Wilkinson H, Chen J. Characterization of a novel small molecule subtype specific estrogen-related receptor alpha antagonist in MCF-7 breast cancer cells. PLoS ONE. 2009;4:e5624 pubmed publisher

Lee G, White L, Hurov K, Stappenbeck T, Piwnica Worms H. Response of small intestinal epithelial cells to acute disruption of cell division through CDC25 deletion. Proc Natl Acad Sci U S A. 2009;106:4701-6 pubmed publisher

Bechard M, Dalton S. Subcellular localization of glycogen synthase kinase 3beta controls embryonic stem cell self-renewal. Mol Cell Biol. 2009;29:2092-104 pubmed publisher

Algar E, Muscat A, Dagar V, Rickert C, Chow C, Biegel J, et al. Imprinted CDKN1C is a tumor suppressor in rhabdoid tumor and activated by restoration of SMARCB1 and histone deacetylase inhibitors. PLoS ONE. 2009;4:e4482 pubmed publisher

Cinelli P, Casanova E, Uhlig S, Lochmatter P, Matsuda T, Yokota T, et al. Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3. BMC Dev Biol. 2008;8:57 pubmed publisher

Zheng Y, Sun D, Sharma A, Chen G, Amin S, Lazarus P. Elimination of antiestrogenic effects of active tamoxifen metabolites by glucuronidation. Drug Metab Dispos. 2007;35:1942-8 pubmed

Yu D, Forman B. Simple and efficient production of (Z)-4-hydroxytamoxifen, a potent estrogen receptor modulator. J Org Chem. 2003;68:9489-91 pubmed

Jørgensen M, Vendelbo B, Skakkebaek N, Leffers H. Assaying estrogenicity by quantitating the expression levels of endogenous estrogen-regulated genes. Environ Health Perspect. 2000;108:403-12 pubmed

McCague R, Leclercq G, Jordan V. Nonisomerizable analogues of (Z)- and (E)-4-hydroxytamoxifen. Synthesis and endocrinological properties of substituted diphenylbenzocycloheptenes. J Med Chem. 1988;31:1285-90 pubmed

Osborne C, Coronado E, Allred D, Wiebe V, DeGregorio M. Acquired tamoxifen resistance: correlation with reduced breast tumor levels of tamoxifen and isomerization of trans-4-hydroxytamoxifen. J Natl Cancer Inst. 1991;83:1477-82 pubmed

Osborne C, Wiebe V, McGuire W, Ciocca D, DeGregorio M. Tamoxifen and the isomers of 4-hydroxytamoxifen in tamoxifen-resistant tumors from breast cancer patients. J Clin Oncol. 1992;10:304-10 pubmed